W. Mark Saltzman
American academic
W. Mark Saltzman's AcademicInfluence.com Rankings
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Chemistry
W. Mark Saltzman's Degrees
- Bachelors Chemical Engineering University of Cincinnati
Why Is W. Mark Saltzman Influential?
(Suggest an Edit or Addition)According to Wikipedia, William Mark Saltzman was named the Goizueta Foundation Professor of Biomedical and Chemical Engineering at Yale University on July 1, 2002 and became the founding chair of Yale's Department of Biomedical Engineering in 2003. Saltzman's research aims to promote new methods for drug delivery and develop new biotechnologies to combat human disease. A pioneer in the fields of biomaterials, nanobiotechnology, and tissue engineering, Saltzman has contributed to the design and implementation of a number of clinical technologies that have become essential to medical practice today. His popular course Frontiers of Biomedical Engineering is available to everyone through Open Yale Courses.
W. Mark Saltzman's Published Works
Published Works
- Synthetic DNA delivery systems (2000) (1582)
- MicroRNA silencing for cancer therapy targeted to the tumor microenvironment (2014) (665)
- Selective cell transplantation using bioabsorbable artificial polymers as matrices. (1988) (573)
- Enhancement of transfection by physical concentration of DNA at the cell surface (2000) (532)
- Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling (2010) (496)
- Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma (2012) (440)
- Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA (2009) (425)
- Enhanced and prolonged cross‐presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles (2006) (401)
- The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. (2009) (381)
- Poly(ethylene glycol)-Conjugated PAMAM Dendrimer for Biocompatible, High-Efficiency DNA Delivery (2002) (356)
- Antibody diffusion in human cervical mucus. (1994) (345)
- Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. (2011) (337)
- PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. (2009) (322)
- Polymeric nanoparticles for drug delivery to the central nervous system. (2012) (310)
- Building drug delivery into tissue engineering design (2002) (299)
- A holistic approach to targeting disease with polymeric nanoparticles (2015) (296)
- Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain. (1998) (282)
- Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. (2009) (282)
- Therapeutic siRNA: Principles, Challenges, and Strategies (2012) (270)
- Pharmacokinetics of the Carmustine Implant (2002) (249)
- Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus. (2009) (240)
- The influence of microchannels on neurite growth and architecture. (2005) (233)
- Drug Delivery: Engineering Principles for Drug Therapy (2001) (211)
- Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma (2013) (208)
- Biomaterials with hierarchically defined micro- and nanoscale structure. (2004) (203)
- Fibronectin terminated multilayer films: protein adsorption and cell attachment studies. (2007) (200)
- Distribution of nerve growth factor following direct delivery to brain interstitium (1995) (198)
- Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification. (2004) (195)
- Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model. (2008) (186)
- Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting. (2005) (186)
- Chemotherapeutic Drugs Released from Polymers: Distribution of 1,3-bis(2-chloroethyl)-l-nitrosourea in the Rat Brain (1996) (184)
- Surface-mediated gene transfer from nanocomposites of controlled texture (2004) (182)
- Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. (2009) (177)
- Neutrophil motility in extracellular matrix gels: mesh size and adhesion affect speed of migration. (1997) (172)
- Drugs released from polymers: diffusion and elimination in brain tissue (1991) (171)
- A self-assembled, modular DNA delivery system mediated by silica nanoparticles. (2004) (162)
- Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. (2012) (162)
- Controlled DNA Delivery Systems (1999) (161)
- Controlled release for local delivery of drugs: barriers and models. (2014) (155)
- Polyanhydride microspheres as drug carriers. II. Microencapsulation by solvent removal (1988) (144)
- Tissue‐engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel (2011) (143)
- Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties. (2003) (142)
- Transport rates of proteins in porous materials with known microgeometry. (1989) (140)
- Transplantation of brain cells assembled around a programmable synthetic microenvironment (2001) (135)
- Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. (2010) (132)
- Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies (2015) (131)
- Targeted for drug delivery (2005) (130)
- A Sunblock Based On Bioadhesive Nanoparticles (2015) (125)
- New Methods for Direct Delivery of Chemotherapy for Treating Brain Tumors (2006) (124)
- miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer. (2016) (121)
- Nanotechnology for delivery of drugs to the brain for epilepsy (2009) (120)
- Cellular Fate of a Modular DNA Delivery System Mediated by Silica Nanoparticles (2008) (116)
- Topographical control of human neutrophil motility on micropatterned materials with various surface chemistry. (2002) (116)
- Fabrication and characterization of microfluidic probes for convection enhanced drug delivery. (2006) (114)
- Novel Delivery Strategies for Glioblastoma (2012) (111)
- Mathematical modeling of molecular diffusion through mucus. (2009) (111)
- Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides. (2011) (110)
- Quantification of human neutrophil motility in three-dimensional collagen gels. Effect of collagen concentration. (1992) (110)
- Controlled release of dopamine from a polymeric brain implant: In vivo characterization (1989) (110)
- Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels. (2005) (108)
- In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery. (2011) (108)
- Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors (2011) (107)
- Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy. (2011) (106)
- Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues (2004) (106)
- The effect of hyperbranched polyglycerol coatings on drug delivery using degradable polymer nanoparticles. (2014) (104)
- In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery (2016) (103)
- High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine. (2008) (102)
- Multilayer nanofilms as substrates for hepatocellular applications. (2008) (102)
- In utero nanoparticle delivery for site-specific genome editing (2018) (100)
- Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery. (2009) (99)
- Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles (2007) (96)
- Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells. (2007) (95)
- Nanosystems for simultaneous imaging and drug delivery to T cells (2007) (93)
- Centrifugal seeding increases seeding efficiency and cellular distribution of bone marrow stromal cells in porous biodegradable scaffolds. (2007) (92)
- Cellular distribution of injected PLGA-nanoparticles in the liver. (2016) (92)
- Controlled release of nerve growth factor from a polymeric implant (1990) (92)
- A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres. (2006) (91)
- Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization. (2010) (90)
- Transport and elimination of recombinant human NGF during long-term delivery to the brain (1996) (89)
- Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection. (2012) (88)
- Design opportunities for actively targeted nanoparticle vaccines. (2008) (88)
- Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys (2017) (87)
- Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. (2011) (87)
- Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants. (1995) (86)
- Intracranial Delivery of Recombinant Nerve Growth Factor: Release Kinetics and Protein Distribution for Three Delivery Systems (1999) (85)
- Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization. (2016) (81)
- Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. (2012) (80)
- Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix. (1994) (78)
- Drug delivery: Stealth particles give mucus the slip. (2009) (77)
- Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates. (2011) (76)
- An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds. (2013) (74)
- Diffusion of nerve growth factor in rat striatum as determined by multiphoton microscopy. (2003) (73)
- Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo (2012) (73)
- Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells (2020) (72)
- Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium (2015) (72)
- Sustained delivery of proangiogenic microRNA‐132 by nanoparticle transfection improves endothelial cell transplantation (2014) (71)
- Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery. (2012) (71)
- Biodegradable Microspheres with Enhanced Capacity for Covalently Bound Surface Ligands (2004) (69)
- Oral immunization with an anti–idiotypic antibody to the exoglycolipid antigen protects against experimental Chlamydia trachomatis infection (1996) (68)
- Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells (2017) (68)
- Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation (2008) (68)
- Stabilization of nerve growth factor in controlled release polymers and in tissue. (1996) (67)
- Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9. (2015) (67)
- Macromolecules released from polymers: diffusion into unstirred fluids. (1990) (66)
- Cell aggregation and neurite growth in gels of extracellular matrix molecules (1994) (66)
- Surface-Modified Nanoparticles Enhance Transurothelial Penetration and Delivery of Survivin siRNA in Treating Bladder Cancer (2013) (65)
- Surface chemistry governs cellular tropism of nanoparticles in the brain (2017) (65)
- Polymeric vehicles for nucleic acid delivery. (2020) (63)
- Focus on Fundamentals: Achieving Effective Nanoparticle Targeting. (2018) (62)
- Polymeric controlled release of dexamethasone in normal rat brain (1991) (62)
- Nanoparticle-mediated intratumoral inhibition of miR-21 for improved survival in glioblastoma. (2019) (61)
- Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders. (1996) (59)
- In vitro cytotoxicity and in vivo distribution after direct delivery of PEG-camptothecin conjugates to the rat brain. (2004) (59)
- Millimeter-scale positioning of a nerve-growth-factor source and biological activity in the brain. (1999) (59)
- Bioengineering Approaches to Controlled Protein Delivery (2008) (59)
- Cell-binding Peptides Conjugated to Poly(ethylene glycol) Promote Neural Cell Aggregation (1994) (59)
- The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus. (2014) (58)
- Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities (2017) (58)
- Controlled release of dopamine from a polymeric brain implant: In vitro characterization (1989) (57)
- DNA diffusion in mucus: effect of size, topology of DNAs, and transfection reagents. (2006) (57)
- Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors. (2016) (57)
- PC12 CELL AGGREGATION AND NEURITE GROWTH IN GELS OF COLLAGEN, LAMININ AND FIBRONECTIN (1996) (56)
- Blocking MHC class II on human endothelium mitigates acute rejection. (2016) (56)
- Growth versus Function in the Three‐Dimensional Culture of Single and Aggregated Hepatocytes within Collagen Gels (1993) (55)
- Pericytes modulate endothelial sprouting. (2013) (55)
- Systemic delivery of blood–brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue (2015) (54)
- Human aortic smooth muscle cells promote arteriole formation by coengrafted endothelial cells. (2009) (54)
- A holistic approach to targeting disease with polymeric nanoparticles (2015) (53)
- Micron-scale positioning of features influences the rate of polymorphonuclear leukocyte migration. (2001) (53)
- Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix. (2003) (53)
- The NIH Somatic Cell Genome Editing program (2021) (53)
- Multi-layered nanoparticles for combination gene and drug delivery to tumors. (2014) (52)
- Controlled vaginal delivery of antibodies in the mouse. (1992) (52)
- Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing (2018) (51)
- Leukocytes migrate through three-dimensional gels of midcycle cervical mucus. (1994) (51)
- Improved i.p. drug delivery with bioadhesive nanoparticles (2016) (51)
- Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters. (2011) (50)
- Synthetic polymers alter the structure of cervical mucus. (2001) (50)
- Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy (2017) (50)
- Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. (2013) (50)
- Nanotechnology for delivery of peptide nucleic acids (PNAs). (2016) (49)
- Three‐dimensional Cell Cultures Mimic Tissues a (1992) (49)
- Nonviral gene delivery: Thinking of silica (2006) (49)
- Canonical and non-canonical barriers facing antimiR cancer therapeutics. (2013) (48)
- 3D bioprinting of a vascularized and perfusable skin graft using human keratinocytes, (...). (2019) (47)
- The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats (2010) (47)
- Initial evaluation of the use of USPIO cell labeling and noninvasive MR monitoring of human tissue‐engineered vascular grafts in vivo (2008) (47)
- The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation. (2014) (46)
- PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma. (2016) (46)
- Cell interactions with polymers (2020) (46)
- Degradable bioadhesive nanoparticles for prolonged intravaginal delivery and retention of elvitegravir. (2017) (45)
- Controlled growth factor delivery induces differential neurite outgrowth in three-dimensional cell cultures (1993) (44)
- Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. (2018) (44)
- Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance (2021) (44)
- Distribution of drugs following controlled delivery to the brain interstitium (1995) (43)
- Fibroblast and hepatocyte behavior on synthetic polymer surfaces. (1991) (43)
- Radiolabeling of Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomography (2014) (41)
- In vitro evaluation of biodegradable microspheres with surface-bound ligands. (2006) (41)
- Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery. (2020) (40)
- Biodegradable PEG-poly(ω-pentadecalactone-co-p-dioxanone) nanoparticles for enhanced and sustained drug delivery to treat brain tumors. (2018) (40)
- Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance (2015) (39)
- Unadjuvanted intranasal spike vaccine booster elicits robust protective mucosal immunity against sarbecoviruses (2022) (39)
- Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery. (2011) (39)
- Fibroblast aggregation by suspension with conjugates of poly(ethylene glycol) and RGD (2000) (39)
- A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery. (2018) (38)
- Influence of synthetic polymers on neutrophil migration in three-dimensional collagen gels. (1999) (38)
- Poly(lactide-co-glycolide) nanoparticle assembly for highly efficient delivery of potent therapeutic agents from medical devices. (2010) (38)
- Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses (2022) (37)
- Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion (2004) (36)
- Localized Delivery of Proteins in the Brain: Can Transport Be Customized? (1998) (36)
- Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. (2014) (36)
- Hydraulic resistance of red cell beds in an unstirred filtration cell (1989) (36)
- Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice (2013) (36)
- Biomedical Engineering: Bridging Medicine and Technology (2015) (35)
- Controlled antibody release from a matrix of poly(ethylene‐co‐vinyl acetate) fractionated with a supercritical fluid (1993) (35)
- Delivering tissue regeneration (1999) (35)
- Modified Poly(lactic‐co‐glycolic Acid) Nanoparticles for Enhanced Cellular Uptake and Gene Editing in the Lung (2015) (34)
- Biomimetic design in microparticulate vaccines. (2003) (34)
- Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA (2013) (33)
- Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair (2020) (33)
- Nerve growth factor delivery systems. (1998) (33)
- Polymers for tissue engineering (1996) (32)
- Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A (2014) (32)
- Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating. (2010) (32)
- Correction of F508del CFTR in airway epithelium using nanoparticles delivering triplex-forming PNAs (2015) (32)
- Targeted genome modification via triple helix formation. (2021) (32)
- Escaping the endosome: Assessing cellular trafficking mechanisms of non-viral vehicles. (2021) (32)
- CHAPTER 19 – CELL INTERACTIONS WITH POLYMERS (2000) (31)
- Tunability of Biodegradable Poly(amine- co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications. (2018) (31)
- A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. (2007) (31)
- Residence half-life of IgG administered topically to the mouse vagina. (1996) (31)
- From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection (2017) (30)
- N‐acetylglucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response (1994) (30)
- N‐acetylglucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response (1994) (30)
- Novel systems for controlled delivery of macromolecules. (1996) (29)
- Pigment epithelium‐derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade (2016) (29)
- Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5 (2013) (29)
- Optimizing Biodegradable Nanoparticle Size for Tissue-Specific Delivery. (2019) (28)
- Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells (2016) (28)
- Controlling human polymorphonuclear leukocytes motility using microfabrication technology. (2000) (28)
- Polymeric controlled delivery for immunization. (1997) (28)
- Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures. (2009) (27)
- Topical antibody delivery systems produce sustained levels in mucosal tissue and blood (1998) (27)
- Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures. (2006) (26)
- Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate. (1999) (26)
- Lysis of cold‐storage‐induced microvascular obstructions for ex vivo revitalization of marginal human kidneys (2020) (26)
- The anti-idiotypic antibody to chlamydial glycolipid exoantigen (GLXA) protects mice against genital infection with a human biovar of Chlamydia trachomatis. (2001) (26)
- Nanomedicine gets personal (2015) (26)
- Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. (2010) (26)
- Antigen-releasing polymer rings and microspheres stimulate mucosal immunity in the vagina. (1998) (26)
- Clostridium perfringens enterotoxin C‐terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy‐resistant ovarian cancer (2015) (26)
- Long-term vaginal antibody delivery: delivery systems and biodistribution. (2000) (26)
- Shining light on a new class of hydrogels (2009) (26)
- Growth-Factor Delivery in Tissue Engineering (1996) (25)
- Synthesis and characterization of polymer-(multi)-peptide conjugates for control of specific cell aggregation. (1998) (24)
- Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel. (2013) (24)
- Oligosaccharyltransferase Inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity (2018) (24)
- Development of a model system for preliminary evaluation of tissue-engineered vascular conduits. (2006) (24)
- Nanoparticle delivery of miR-223 to attenuate macrophage fusion. (2016) (24)
- Extracellular Matrix and Cell Adhesion (2010) (24)
- Quantitative image analysis for developing microstructural descriptions of heterogeneous materials (1987) (24)
- Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity. (2010) (24)
- Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic. (2008) (23)
- Controlled release of macromolecules from a degradable polyanhydride matrix. (1994) (23)
- Nanomedicine: Downsizing tumour therapeutics. (2012) (23)
- Controlled Antibody Delivery Systems (1992) (23)
- Prevention of K-Ras- and Pten-mediated intravaginal tumors by treatment with camptothecin-loaded PLGA nanoparticles (2011) (22)
- Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas (2017) (22)
- Nanomaterials for convection-enhanced delivery of agents to treat brain tumors. (2017) (20)
- Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension (2021) (20)
- In vivo correction of anaemia in beta-thalassemic mice by gammaPNA-mediated gene editing with nanoparticle delivery (2019) (20)
- Replacement of bone marrow by bone in rat femurs: the bone bioreactor. (2008) (20)
- Dextran Retention in the Rat Brain Following Release from a Polymer Implant (1992) (20)
- PEGylation of poly(amine-co-ester) polyplexes for tunable gene delivery. (2021) (19)
- Simultaneous release of multiple molecules from poly(lactide-co-glycolide) nanoparticles assembled onto medical devices. (2009) (19)
- Biodegradable bioadhesive nanoparticle incorporation of broad‐spectrum organic sunscreen agents (2018) (18)
- Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele. (2019) (18)
- Aggregation enhances catecholamine secretion in cultured cells. (2001) (18)
- Antibodies to CD18 influence neutrophil migration through extracellular matrix (1999) (17)
- Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver. (2019) (17)
- Multifunctional Poly(amine-co-ester-co-ortho ester) for Efficient and Safe Gene Delivery. (2016) (17)
- Polymer delivery systems for site-specific genome editing. (2011) (15)
- Conjugation to increase treatment volume during local therapy: a case study with PEGylated camptothecin. (2007) (14)
- Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. (2019) (14)
- Nerve growth factor delivery and cell aggregation enhance choline acetyltransferase activity after neural transplantation. (1996) (14)
- Antibodies for treating and preventing disease: the potential role of polymeric controlled release. (1993) (14)
- Nonsurgical treatment of skin cancer with local delivery of bioadhesive nanoparticles (2021) (14)
- Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. (2019) (13)
- Chapter Twenty – Cell Interactions with Polymers (2007) (12)
- Simultaneous delivery of an active protein and neutralizing antibody: creation of separated regions of biological activity. (2001) (12)
- Cultures of cells from fetal rat brain: methods to control composition, morphology, and biochemical activity. (1999) (12)
- Debugging the genetic code: non-viral in vivo delivery of therapeutic genome editing technologies. (2018) (12)
- Influence of structural parameters on the ring‐opening polymerization of new alkyl malolactonate monomers and on the biocompatibility of polymers therefrom (2002) (12)
- The Yale Center for Biomedical Innovation and Technology (CBIT): One Model to Accelerate Impact From Academic Health Care Innovation. (2019) (12)
- Protein delivery from nondegradable polymer matrices. (1997) (11)
- Controlled Intracranial Delivery of Antibodies in the Rat (1994) (11)
- The effect of synthetic polymers on the migration of monocytes through human cervical mucus. (2004) (11)
- Surface-modified biodegradable microspheres for DNA vaccine delivery. (2006) (11)
- Fas ligand and nitric oxide combination to control smooth muscle growth while sparing endothelium. (2019) (11)
- Tuning protein half-life in mouse using sequence-defined biopolymers functionalized with lipids (2022) (10)
- Spermicide permeation through biocompatible polymers. (1991) (10)
- Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo. (2020) (9)
- Direct targeting of amplified gene loci for pro-apoptotic anticancer therapy (2021) (9)
- Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence (2015) (9)
- Nanoparticles for Delivery of Agents to Fetal Lungs. (2021) (9)
- Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism. (2005) (9)
- Microstructural Models for Diffusive Transport in Porous Polymers (1987) (9)
- Glycoprotein-130 Expression Is Associated with Aggressive Bladder Cancer and Is a Potential Therapeutic Target (2018) (8)
- Efficacy of camptothecin and polymer-conjugated camptothecin in tumor spheroids and solid tumors (2007) (8)
- Controlled protein delivery in the generation of microvascular networks (2015) (8)
- Surface patterning and biological evaluation of semi-interpenetrated poly(HEMA)/poly(alkyl β-malolactonate)s (2003) (7)
- Controlled delivery of antibodies against leukocyte adhesion molecules from polymer matrices (1996) (7)
- Interstitial Transport in the Brain: Principles for Local Drug Delivery (2006) (7)
- Are We Studying What Matters? Health Priorities and NIH-Funded Biomedical Engineering Research (2010) (7)
- Inhalable polymer nanoparticles for versatile mRNA delivery and mucosal vaccination (2022) (6)
- High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents (2020) (6)
- A microstructural approach for modelling diffusion of bioactive macromolecules in porous polymers (1987) (6)
- Novel Drug Delivery Systems for Posterior Segment Ocular Disease (2006) (6)
- Enhanced growth and hepatic differentiation of fetal liver epithelial cells through combinational and temporal adjustment of soluble factors (2012) (6)
- Computer Based Visualization for Quantitative and Qualitative Analysis of the Distribution of Matrix-Bound Proteins (1988) (6)
- Fish passage through culverts (1971) (6)
- Improved threshold selection for the determination of volume of distribution of nanoparticles administered by convection-enhanced delivery (2017) (5)
- Stealth particles give mucus the slip (2014) (5)
- Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes. (2017) (5)
- ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage (2022) (5)
- Surface Topography of Polyethylene Glycol Shell Nanoparticles Formed from Bottlebrush Block Copolymers Controls Interactions with Proteins and Cells. (2021) (5)
- 3D bioprinting of an implantable xeno‐free vascularized human skin graft (2022) (5)
- 4.30 Nanomaterials for Drug Delivery to the Brain (2017) (4)
- Transport in Porous Polymers (1990) (4)
- Development of PTH eluting microspheres for the treatment of hypoparathyroidism. (2007) (4)
- In vivo correction of cystic fibrosis mediated by PNA nanoparticles (2022) (4)
- Extracellular vesicles mediated exocytosis of antisense peptide nucleic acids (2021) (4)
- Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium (2020) (4)
- Long‐acting and extended‐release implant and nanoformulations with a synergistic antiretroviral two‐drug combination controls HIV‐1 infection in a humanized mouse model (2021) (4)
- Weaving cartilage at zero g: the reality of tissue engineering in space. (1997) (4)
- Intrathecal Delivery and its Applications in Leptomeningeal Disease. (2022) (4)
- Direct, Quantitative, and Noninvasive Imaging of the Transport of Active Agents Through Intact Brain with Positron Emission Tomography (2013) (4)
- Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis. (2022) (3)
- Cost-reducing protein production and delivery for sexually transmitted disease prevention. (2003) (3)
- Malolactonate polymers and copolymers for biomedical applications (2003) (3)
- Drug discovery and delivery. (1995) (3)
- Micro-engineered biomineralized materials for bone tissue engineering (2002) (3)
- Polyglycerol and Poly(ethylene glycol) exhibit different effects on pharmacokinetics and antibody generation when grafted to nanoparticle surfaces. (2022) (2)
- Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy (2022) (2)
- EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2013) (2)
- Enzymatic synthesis of poly(amine-co-esters) for gene delivery (2013) (2)
- Cross-platform analysis reveals cellular and molecular landscape of glioblastoma invasion. (2022) (2)
- Drug delivery systems (2018) (2)
- [18F]PEG-Biotin labeled nanoparticles for tracking drug delivery and tumor therapy (2011) (2)
- Engineering alginate microparticles for optimized accumulation in Fetal Rat Myelomeningocele. (2021) (2)
- Biomedical Engineering: Index (2009) (1)
- 1055 SURFACE MODIFICATIONS OF POLY(LACTIDE-CO-GLYCOLIDE) NANOPARTICLES CAN INCREASE ITS UPTAKE BY BLADDER CANCER CELLS (2011) (1)
- Tissue-Engineered Microvasculature to Reperfuse Isolated Renal Glomeruli. (2015) (1)
- Cell and Tissue Mechanics (2004) (1)
- Small Pedf Peptides Encapsulated in Controlled Release Poly (Lactic–co–Glycolic) Acid Microspheres Protect Retinal Ganglion Cells From Transient Ischemic Injury (2005) (1)
- Effect of vorinostat (V)-loaded PLGA nanoparticles (NP) surface modified with a PSMA ligand on prostate cancer (PC) cells. (2010) (1)
- Polymers for cancer gene therapy: Browsing the library (2005) (1)
- DNA vaccines : methods and protocols (2006) (1)
- New encounters with the Sphinx (1998) (1)
- Inflammasome-activating biodegradable nanoparticulates as vaccine delivery systems (135.80) (2009) (1)
- LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY (2012) (1)
- Diffusion measurements for drug design (2005) (1)
- Transport of 1,3-bis(1,2-chloroethyl)-1-nitrosourea (BCNU) in the brain transport of following controlled release by a polymer (1995) (1)
- Nanoparticle Targeting with Antibodies in the Central Nervous System (2023) (1)
- Intra-amniotic Injection of Poly(lactic-co-glycolic Acid) Microparticles Loaded with Growth Factor: Effect on Tissue Coverage and Cellular Apoptosis in the Rat Model of Myelomeningocele. (2022) (1)
- MP-04.16 Uptake of Surface Modified Poly(Lactide-Co-Glycolide) Nanoparticles in Bladder Cancer Cells and in Human Ureter and Mouse Bladder (2011) (1)
- Knowledge Discovery by Decision Tree to Model the Rate of Drug Release from Matrix Substrates (2016) (1)
- Cell Structure and Motion, Extracellular Matrix and Cell Adhesion (2003) (1)
- Synthetic biodegradable polyesters for implantable controlled-release devices (2022) (1)
- Abstract 364: In vivo targeting of CD44+ ovarian cancer stem cells (CSC) by Clostridium Perfringens Enterotoxin binding domain (CPE-peptide) conjugated to poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP) (2012) (1)
- Abstract 663: Systemic targeting of therapeutic RNA to cancer via a novel, cell-penetrating and nucleic acid binding, monoclonal antibody (2022) (1)
- Biomedical Engineering: Biomechanics (2009) (1)
- Biomedical Engineering: Biomolecular Engineering I: Biotechnology (2009) (0)
- Biomedical Engineering: Bioinstrumentation (2009) (0)
- Depot implant with controlled drug delivery for treatment of diseases of the nervous system. (1988) (0)
- 578 Improved local drug delivery with bioadhesive nanoparticles in the treatment of skin cancer (2020) (0)
- Abstract 4937: Fluorescence imaging usingClostridium Perfringens Enterotoxincarboxi-terminal fragment (c-CPE) to target metastatic chemotherapy-resistant human ovarian cancer in xenograft mice (2014) (0)
- Abstract A86: Preclinical refinement of a highly-penetrative polymeric nanoparticle drug delivery system for the treatment of glioblastoma multiforme. (2013) (0)
- Biomedical Engineering: Cellular Principles (2009) (0)
- Biomedical Engineering: Biomolecular Principles (2009) (0)
- A novel polymer-coated nanoparticle (NP) for urothelium penetration and drug delivery. (2013) (0)
- Biomedical Engineering: Biomedical Engineering and Cancer (2009) (0)
- Long-term delivery of antibodies to the vaginal mucosal surface using controlled-release polymer devices (1997) (0)
- Abstract 1075: Chemically modified gamma PNAs targeting oncomiR-210 as a potential anticancer therapy (2016) (0)
- Bioengineered Controlled Delivery System for the Treatment of Acute Liver Failure (2011) (0)
- Calcium sensitive feedback release of parathyroid hormone as a potential treatment of hypoparathyroidism (2004) (0)
- 666 Biodegradable poly(lactic acid)-hyperbranched polyglycerol nanoparticle encapsulated drug delivery for skin cancer treatment (2017) (0)
- Biomedical Engineering: Biomolecular Engineering II: Engineering of Immunity (2009) (0)
- Engineered molecular delivery for control and enhancement of transplanted endothelial cell fate in tissue engineering (2009) (0)
- HG-112LOCAL DELIVERY OF RADIOSENSITIZING NANOPARTICLES FOR THE TREATMENT OF PEDIATRIC BRAINSTEM GLIOMAS. (2016) (0)
- Interstitial Transport in the Brain: The 10–100 Micron Size Scale (1999) (0)
- LB998 Lymph node delivery of immunstimulatory agent monophosphoryl lipid A via bioadhesive nanoparticles in the treatment of cutaneous melanoma (2022) (0)
- Controlled protein delivery in the generation of microvascular networks (2012) (0)
- Room Temperature Mid-Infrared Light Detection Based on Graphene Plasmons (2018) (0)
- Biomedical Engineering: Biomaterials and Artificial Organs (2009) (0)
- Cell Aggregation and Tissue Equivalents (2004) (0)
- Biomedical Engineering: Introduction: What Is Biomedical Engineering? (2009) (0)
- 1358 NANOPARTICLE DELIVERY OF THE HISTONE DEACETYLASE INHIBITOR PXD101 FACILITATES BLADDER CANCER CELL UPTAKE AND CYTOTOXICITY (2011) (0)
- Drug Permeation through Biological Barriers (2001) (0)
- Biomedical Engineering: Units and Conversion Factors (2009) (0)
- Replacement of Bone Marrow by Bone in Rat Femurs: The Bone Bioreactor (2008) (0)
- PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2010) (0)
- Biomedical Engineering: Physiological Parameters (2009) (0)
- Biomedical Engineering: MOLECULAR AND CELLULAR PRINCIPLES (2009) (0)
- Biomedical Engineering: Chemical Parameters (2009) (0)
- 436 EFFECT OF SURVIVIN SIRNA AND VEGF SIRNA COMPLEXED IN NANOPARTICLES ON BLADDER CANCER CELLS AND UROTHELIAL TISSUES (2010) (0)
- Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications (2022) (0)
- MP49-10 KNOCKDOWN OF GLYCOPROTEIN-130 INHIBITS BLADDER CANCER PROGRESSION AND MIGRATION (2015) (0)
- Abstract A21: High-throughput small molecule screening of genetically diverse glioblastoma stem cells (2012) (0)
- Cell Delivery and Recirculation (2004) (0)
- Analysis of endocytic sorting on regulation of exogenous antigen presentation (2005) (0)
- Cellular delivery for vascularization of engineered tissues: Reduction of contraction by mural cells (2011) (0)
- Abstract 755: Fas Ligand- and Nitric Oxide-Releasing Stent (2019) (0)
- Large Molecule Therapeutics Surface-Modi fi ed Nanoparticles Enhance Transurothelial Penetration and Delivery of Survivin siRNA in Treating Bladder Cancer (2014) (0)
- Dynamic behavior of nerve growth factor upon administration to the rat brain parenchyma (2002) (0)
- Erratum: Long-term vaginal antibody deliver: Delivey systems and biodistribution (Biotechnology and Bioengineering (2001) 67 (253-264)) (2001) (0)
- Biomedical Engineering: Circulation (2009) (0)
- Chemically Modified Gamma PNAs Targeting microRNA-210 as a Novel Anticancer Therapy With Specificity for Hypoxic Solid Tumors (2016) (0)
- Design and testing of polymeric implants for the long-term release of dopamine (1988) (0)
- Biomedical Engineering: Communication Systems in the Body (2009) (0)
- Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells (2022) (0)
- MOLECULAR AND CELLULAR PRINCIPLES (2015) (0)
- Biomedical Engineering: Biomolecular Principles: Nucleic Acids (2009) (0)
- Biomolecular Principles: Proteins (2009) (0)
- NITRIC OXIDE- AND FAS LIGAND- ELUTING COMPOSITIONS AND DEVICES AND METHODS OF TREATMENT USING SAME (2019) (0)
- Convection-Enhanced Delivery of Nanoparticle-Encapsulated Radiosensitizers for Treatment of Malignant Glioma (2016) (0)
- Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment (2023) (0)
- Biomedical Engineering: Preface (2009) (0)
- Biomedical Engineering: Bioimaging (2009) (0)
- 1070 Biodegradable bioadhesive nanoparticle delivery of camptothecin for the treatment of PDV squamous cell carcinoma (2018) (0)
- Biomedical Engineering: Removal of Molecules from the Body (2009) (0)
- Osteopontin eluting microspheres decrease calcification in tissue engineered heart valves (2006) (0)
- Fabrication of PLGA polymer microspheres for U. S. mediated gene delivery (2004) (0)
- Abstract 4747: Redirecting the endogenous immune response against prostate cancer using an antibody-recruiting small molecule (2012) (0)
- 580 Biodegradable bioadhesive nanoparticle delivery of chemotherapy for the treatment of cutaneous malignancies (2022) (0)
- Targeting of Melanoma by pH (Low) Insertion Peptide (pHLIP) (2013) (0)
- Nucleic Acid Delivery to the Vascular Endothelium. (2022) (0)
- Imaging and Treating Tumors by Targeting their Acidity with Phlip, a Ph-Sensitve Insertion Peptide (2014) (0)
- 1019 Biodegradable bioadherent nanoparticle formulation for the local nonsurgical treatment of cutaneous malignancy (2019) (0)
- Nanoparticle-Encapsulated NAMPT Inhibitors Administered via Convection Enhanced Delivery as a Novel Glioma Radiosensitization Strategy (2020) (0)
- Correction for Kudalkar et al., From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection (2018) (0)
- UNCORRECTED PROOF 1 Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic 2 ligand conjugates (2011) (0)
- Biomedical Engineering: Engineering Balances: Respiration and Digestion (2009) (0)
- Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection (2018) (0)
- pHLIP® Targeting and Delivery of PNA to Silence MicroRNA in Tumor Cells§ (2015) (0)
- Chapter 23: PEGylated PLGA Nanoparticles for the Improved Delivery of Doxorubicin (2017) (0)
- Vivo Characterization of Microfluidic Probes for Convection Enhanced Drug Delivery (2005) (0)
- Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells (2017) (0)
- 761 Development of a novel broad-spectrum sunscreen via bioadhesive nanoparticle encapsulation of organic UV filters (2017) (0)
- Polymer nanocarriers for targeted local delivery of agents in treating brain tumors (2022) (0)
- 1068 Formulation and evaluation of topical products with Cannabis Sativa oil (2018) (0)
- In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic hernia (2022) (0)
- Oral anti-idiotypic antibody to chlamydial GLXA reduces genital infection and dissemination to joints (1999) (0)
- Abstract P135: Systemic targeting of a CNS tumor (medulloblastoma) using a novel cell-penetrating, nucleic acid binding, monoclonal antibody (2021) (0)
- Abstract 294: Exploiting mutant PPM1D-induced metabolic defects with nanoparticle-encapsulated NAMPT inhibitors (2022) (0)
- In utero nanoparticle delivery for site-specific genome editing (2018) (0)
- A digital pathology tool for quantification of color features in histologic specimens (2021) (0)
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