William Paul Duprex
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William Paul Duprexbiology Degrees
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Biology
William Paul Duprex's Degrees
- Bachelors Microbiology University of Oxford
Why Is William Paul Duprex Influential?
(Suggest an Edit or Addition)According to Wikipedia, William Paul Duprex is a British scientist and advocate for vaccines and global health. He serves as Director of the University of Pittsburgh's Center for Vaccine Research and Regional Biocontainment Laboratory. Duprex holds the Jonas Salk Chair in Vaccine Research. He is also a professor of microbiology and molecular genetics at the University of Pittsburgh School of Medicine and serves as Editor-in-Chief of the Journal of General Virology, which is published by the Microbiology Society, and a senior editor of mSphere, published by the American Society for Microbiology. Duprex is an expert in measles and mumps viruses and studies viral spillover from animals to humans, including the SARS-CoV-2 virus that caused the COVID-19 pandemic. Duprex is a Fellow of the American Academy of Microbiology.
William Paul Duprex's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Animal models for COVID-19 (2020) (582)
- Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling (2002) (529)
- Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (453)
- Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape (2021) (296)
- Predominant Infection of CD150+ Lymphocytes and Dendritic Cells during Measles Virus Infection of Macaques (2007) (251)
- Taxonomy of the order Mononegavirales: update 2019 (2019) (237)
- Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2 (2020) (228)
- Early Target Cells of Measles Virus after Aerosol Infection of Non-Human Primates (2011) (202)
- Observation of Measles Virus Cell-to-Cell Spread in Astrocytoma Cells by Using a Green Fluorescent Protein-Expressing Recombinant Virus (1999) (196)
- Natural deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape (2020) (160)
- Measles Immune Suppression: Lessons from the Macaque Model (2012) (156)
- Molecular biology, pathogenesis and pathology of mumps virus (2015) (144)
- 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2020) (122)
- Polyploid measles virus with hexameric genome length (2002) (120)
- Dynamics of Viral RNA Synthesis during Measles Virus Infection (2005) (114)
- Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5. (2014) (114)
- Molecular mechanisms of measles virus persistence. (2005) (113)
- Measles Virus Host Invasion and Pathogenesis (2016) (113)
- Morbilliviruses and human disease (2006) (108)
- In Vivo Tropism of Attenuated and Pathogenic Measles Virus Expressing Green Fluorescent Protein in Macaques (2010) (104)
- SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts (2020) (102)
- Analysis of receptor (CD46, CD150) usage by measles virus. (2002) (102)
- Phocine Distemper Virus: Current Knowledge and Future Directions (2014) (99)
- Modulating the Function of the Measles Virus RNA-Dependent RNA Polymerase by Insertion of Green Fluorescent Protein into the Open Reading Frame (2002) (97)
- Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus* (2010) (90)
- Measles virus suppresses RIG-I-like receptor activation in dendritic cells via DC-SIGN-mediated inhibition of PP1 phosphatases. (2014) (85)
- Recent Mumps Outbreaks in Vaccinated Populations: No Evidence of Immune Escape (2011) (84)
- Deletion disrupts a conserved antibody epitope in a SARS-CoV-2 variant of concern (2021) (83)
- Measles virus M and F proteins associate with detergent-resistant membrane fractions and promote formation of virus-like particles. (2007) (78)
- SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients (2020) (77)
- Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses (2021) (73)
- Pathological consequences of systemic measles virus infection (2015) (73)
- The H Gene of Rodent Brain-Adapted Measles Virus Confers Neurovirulence to the Edmonston Vaccine Strain (1999) (72)
- Establishment of a Rescue System for Canine Distemper Virus (2000) (66)
- Intractable COVID-19 and Prolonged SARS-CoV-2 Replication in a CAR-T-cell Therapy Recipient: A Case Study. (2021) (66)
- Taxonomy of the order Mononegavirales: second update 2018 (2019) (66)
- Morbillivirus Infections: An Introduction (2015) (65)
- In Vitro and In Vivo Infection of Neural Cells by a Recombinant Measles Virus Expressing Enhanced Green Fluorescent Protein (2000) (64)
- Wild-type measles virus infection of primary epithelial cells occurs via the basolateral surface without syncytium formation or release of infectious virus. (2010) (62)
- Measles Virus Infection of Epithelial Cells in the Macaque Upper Respiratory Tract Is Mediated by Subepithelial Immune Cells (2013) (58)
- Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike (2021) (56)
- A Prominent Role for DC-SIGN+ Dendritic Cells in Initiation and Dissemination of Measles Virus Infection in Non-Human Primates (2012) (56)
- The measles virus replication cycle. (2009) (56)
- Chronic Infection of Domestic Cats with Feline Morbillivirus, United States (2016) (54)
- Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors (2016) (52)
- Live-Attenuated Measles Virus Vaccine Targets Dendritic Cells and Macrophages in Muscle of Nonhuman Primates (2014) (51)
- BRCA1 Interacts with and Is Required for Paclitaxel-Induced Activation of Mitogen-Activated Protein Kinase Kinase Kinase 3 (2004) (51)
- Foot-and-Mouth Disease Virus, but Not Bovine Enterovirus, Targets the Host Cell Cytoskeleton via the Nonstructural Protein 3Cpro (2008) (50)
- Gain-of-function experiments: time for a real debate (2014) (50)
- Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study (2021) (49)
- Rational Attenuation of a Morbillivirus by Modulating the Activity of the RNA-Dependent RNA Polymerase (2005) (48)
- Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike (2021) (48)
- Recombinant Canine Distemper Virus Strain Snyder Hill Expressing Green or Red Fluorescent Proteins Causes Meningoencephalitis in the Ferret (2012) (47)
- Rinderpest eradication: lessons for measles eradication? (2012) (45)
- The F Gene of Rodent Brain-Adapted Mumps Virus Is a Major Determinant of Neurovirulence (2007) (45)
- Measles Vaccination of Nonhuman Primates Provides Partial Protection against Infection with Canine Distemper Virus (2014) (45)
- 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2021) (44)
- Using the ferret model to study morbillivirus entry, spread, transmission and cross-species infection. (2014) (43)
- Efficient and Robust Paramyxoviridae Reverse Genetics Systems (2017) (43)
- SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients (2020) (43)
- Development of a Challenge-Protective Vaccine Concept by Modification of the Viral RNA-Dependent RNA Polymerase of Canine Distemper Virus (2007) (43)
- Streptococcus pneumoniae Enhances Human Respiratory Syncytial Virus Infection In Vitro and In Vivo (2015) (42)
- Towards ambient temperature-stable vaccines: the identification of thermally stabilizing liquid formulations for measles virus using an innovative high-throughput infectivity assay. (2011) (41)
- Infection of lymphoid tissues in the macaque upper respiratory tract contributes to the emergence of transmissible measles virus. (2013) (41)
- The pathogenesis of measles. (2012) (40)
- Mapping the evolutionary trajectories of morbilliviruses: what, where and whither (2016) (39)
- Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses (2021) (37)
- Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses (2017) (36)
- Delineating morbillivirus entry, dissemination and airborne transmission by studying in vivo competition of multicolor canine distemper viruses in ferrets (2017) (36)
- Non-detection of Chlamydia species in carotid atheroma using generic primers by nested PCR in a population with a high prevalence of Chlamydia pneumoniae antibody (2001) (35)
- Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis (2016) (33)
- A mouse model of persistent brain infection with recombinant Measles virus. (2006) (32)
- 'Rescue' of mini-genomic constructs and viruses by combinations of morbillivirus N, P and L proteins. (2005) (31)
- Approaches in the understanding of morbillivirus neurovirulence. (2002) (30)
- Paramyxovirus infections in ex vivo lung slice cultures of different host species. (2013) (28)
- Gene-Specific Contributions to Mumps Virus Neurovirulence and Neuroattenuation (2011) (27)
- Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection (2017) (27)
- Molecular differences between two Jeryl Lynn mumps virus vaccine component strains, JL5 and JL2 (2009) (26)
- Recombinant Subgroup B Human Respiratory Syncytial Virus Expressing Enhanced Green Fluorescent Protein Efficiently Replicates in Primary Human Cells and Is Virulent in Cotton Rats (2014) (25)
- Determination of Spontaneous Mutation Frequencies in Measles Virus under Nonselective Conditions (2012) (25)
- Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. (2020) (24)
- Macrophages and Dendritic Cells Are the Predominant Cells Infected in Measles in Humans (2018) (23)
- A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting (2009) (22)
- Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents (2016) (21)
- Measles Virus-Induced Disruption of the Glial-Fibrillary-Acidic Protein Cytoskeleton in an Astrocytoma Cell Line (U-251) (2000) (21)
- Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae (2019) (21)
- Versatile, Multivalent Nanobody Cocktails Efficiently Neutralize SARS-CoV-2 (2020) (21)
- CD9-dependent regulation of Canine distemper virus-induced cell-cell fusion segregates with the extracellular domain of the haemagglutinin. (2006) (21)
- Measles virus superinfection immunity and receptor redistribution in persistently infected NT2 cells. (2005) (21)
- Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist (2009) (20)
- New concepts in measles virus replication: getting in and out in vivo and modulating the host cell environment. (2011) (19)
- Limited in vivo production of type I or type III interferon after infection of macaques with vaccine or wild-type strains of measles virus. (2015) (18)
- Inhibition of Nipah Virus by Defective Interfering Particles. (2020) (18)
- Discrimination of Mumps Virus Small Hydrophobic Gene Deletion Effects from Gene Translation Effects on Virus Virulence (2011) (18)
- Measles virus minigenomes encoding two autofluorescent proteins reveal cell-to-cell variation in reporter expression dependent on viral sequences between the transcription units. (2007) (17)
- Two functionally linked amino acids in the stem 2 region of measles virus haemagglutinin determine infectivity and virulence in the rodent central nervous system. (2007) (17)
- Presence of lysine at aa 335 of the hemagglutinin-neuraminidase protein of mumps virus vaccine strain Urabe AM9 is not a requirement for neurovirulence. (2009) (13)
- Optimization and Dose Estimation of Aerosol Delivery to Non-Human Primates. (2016) (12)
- Measles pathogenesis, immune suppression and animal models. (2020) (12)
- Evaluation of synthetic infection-enhancing lipopeptides as adjuvants for a live-attenuated canine distemper virus vaccine administered intra-nasally to ferrets. (2012) (11)
- Comparative analysis of human immune responses following SARS-CoV-2 vaccination with BNT162b2, mRNA-1273, or Ad26.COV2.S (2021) (11)
- Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis (2020) (11)
- Cross-Reactive and Cross-Neutralizing Activity of Human Mumps Antibodies Against a Novel Mumps Virus From Bats (2016) (9)
- Human Respiratory Syncytial Virus Subgroup A and B Infections in Nasal, Bronchial, Small-Airway, and Organoid-Derived Respiratory Cultures (2021) (9)
- 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2022) (8)
- Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (7)
- Taxonomy of the order Mononegavirales: second update 2018 (2019) (7)
- The phosphoprotein genes of measles viruses from subacute sclerosing panencephalitis cases encode functional as well as non-functional proteins and display reduced editing. (2016) (7)
- Paramyxovirus Infections in Ex Vivo Lung Slice Cultures of Different Host Species (2018) (6)
- Using green fluorescent protein to monitor measles virus cell-to-cell spread by time-lapse confocal microscopy. (2002) (6)
- Novel feline viruses: Emerging significance of gammaherpesvirus and morbillivirus infections (2018) (6)
- In memoriam--Richard M. Elliott (1954-2015). (2015) (5)
- Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization (2022) (5)
- Four principles to establish a universal virus taxonomy (2023) (5)
- Bifurcated monocyte states are predictive of mortality in severe COVID-19 (2021) (5)
- Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales (2021) (5)
- Sustained Replication of Synthetic Canine Distemper Virus Defective Genomes In Vitro and In Vivo (2021) (5)
- Infection of human oligodendroglioma cells by a recombinant measles virus expressing enhanced green fluorescent protein (2011) (5)
- A Cross-Sectional Study of SARS-CoV-2 Seroprevalence between Fall 2020 and February 2021 in Allegheny County, Western Pennsylvania, USA (2021) (5)
- People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden (2021) (4)
- Virology under the Microscope—a Call for Rational Discourse (2023) (4)
- Super-immunity by broadly protective nanobodies to sarbecoviruses (2021) (4)
- In vivo comparison of a laboratory-adapted and clinical-isolate-based recombinant human respiratory syncytial virus. (2020) (4)
- Rift Valley Fever Virus Infection Causes Acute Encephalitis in the Ferret (2020) (4)
- Recombinant subtype A and B human respiratory syncytial virus clinical isolates co-infect the respiratory tract of cotton rats. (2020) (4)
- Human Paramyxoviruses and Infections of the Central Nervous System (2013) (3)
- Title: SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and prolonged shedding of infectious virus from both respiratory and gastrointestinal tracts (2020) (3)
- Superimmunity by pan-sarbecovirus nanobodies (2022) (3)
- Live-cell visualization of transmembrane protein oligomerization and membrane fusion using two-fragment haptoEGFP methodology. (2012) (3)
- Completion of an Experiment (2018) (3)
- mSphere of Influence: the View from the Microbiologists of the Future (2019) (3)
- Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages (2022) (1)
- Falling down the Rabbit Hole: aTRIP Toward Lexiconic Precision in the “Gain-of-Function” Debate (2014) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Whether you are a virus or a learned society-based virology journal, evolution is critical for success! (2018) (1)
- FeMV is a cathepsin-dependent unique morbillivirus infecting the kidneys of domestic cats (2022) (1)
- Foot-and-Mouth Disease Virus, but Not Bovine Enterovirus, Targets the Host Cell Cytoskeleton via the Nonstructural Protein 3C pro (cid:1) (2008) (1)
- A novel mutation in the neuraminidase gene of the 2009 pandemic H1N1 influenza A virus confers multidrug resistance. (2018) (1)
- Measles skin rash: infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to keratinocytes in the epidermis (2019) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry (2022) (0)
- Protein Expressing Enhanced Green Fluorescent by a Recombinant Measles Virus In Vitro and In Vivo Infection of Neural Cells (2000) (0)
- Comparable Infection Level and Tropism of Measles Virus and Canine Distemper Virus in Organotypic Brain Slice Cultures Obtained from Natural Host Species (2021) (0)
- Canine Distemper Virus Establishment of a Rescue System for (2014) (0)
- Live-attenuated measles virus vaccine targets dendritic cells 1 and macrophages in the muscle of non-human primates (2014) (0)
- Correction: Predominant Infection of CD150+ Lymphocytes and Dendritic Cells during Measles Virus Infection of Macaques (2008) (0)
- Taxonomy of the order Mononegavirales: update 2019 (2019) (0)
- Animal models for COVID-19 (2020) (0)
- Biodistribution and toxicology evaluation of a recombinant measles Schwarz‐based Lassa vaccine in cynomolgus macaques (2022) (0)
- Mumps Virus (0)
- Subacute sclerosing panencephalitis and measles inclusion body encephalitis (2017) (0)
- UvA-DARE ( Digital Academic Repository ) Early Target Cells of Measles Virus after Aerosol Infection of Non-Human Primates (2011) (0)
- Molecular assembly of measles and Nipah virus: specific lipid binding drives conformational change and matrix polymerization (2021) (0)
- Measles Virus (2021) (0)
- Communicate, educate: tackling misconceptions to boost vaccine uptake (2015) (0)
- Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection (2017) (0)
- Comparative analysis of human immune responses following SARS-CoV-2 vaccination with BNT162b2, mRNA-1273, or Ad26.COV2.S (2022) (0)
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