William Robert Bruce

William Robert Bruce's AcademicInfluence.com Rankings

Chemistry

#2894

World Rank

#3864

Historical Rank

Physical Chemistry

#361

World Rank

#410

Historical Rank

chemistry Degrees

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Chemistry

William Robert Bruce's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry Stanford University

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William Robert Bruce's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Chemical induction of sperm abnormalities in mice. (1975) (875)
Colon cancer and dietary fat, phosphate, and calcium: a hypothesis. (1984) (549)
Comparison of the Sensitivity of Normal Hematopoietic and Transplanted Lymphoma Colony-Forming Cells to Chemotherapeutic Agents Administered In Vivo (1966) (498)
A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo (1963) (427)
Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. (2006) (347)
Identification and quantification of aberrant crypt foci and microadenomas in the human colon. (1991) (330)
Insulin promotion of colon tumors in rats. (1996) (304)
The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays. (1979) (294)
Nitrite and nitrate are formed by endogenous synthesis in the human intestine. (1978) (285)
Calcium ameliorates the toxic effect of deoxycholic acid on colonic epithelium. (1983) (258)
Possible mechanisms relating diet and risk of colon cancer. (2000) (244)
A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps. (1988) (203)
Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways. (2006) (197)
Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods. (1989) (195)
Mechanisms Linking Diet and Colorectal Cancer: The Possible Role of Insulin Resistance (2000) (188)
A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps. Toronto Polyp Prevention Group. (1994) (184)
Cellular composition of fractions of mouse testis cells following velocity sedimentation separation. (1973) (179)
Classification of aberrant crypt foci and microadenomas in human colon. (1991) (165)
Abnormalities in the shape of murine sperm after acute testicular x-irradiation. (1974) (164)
K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis. (1993) (161)
Effects of calcium and pH on the mucosal damage produced by deoxycholic acid in the rat colon. (1986) (149)
THE EFFECT OF ERYTHROPOIETIC STIMULATION ON THE HEMOPOIETIC COLONY-FORMING CELLS OF MICE. (1964) (144)
The separation, physical characterization, and differentiation kinetics of spermatogonial cells of the mouse. (1970) (142)
Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo. (2006) (136)
Effect of high fat consumption on cell proliferation activity of colorectal mucosa and on soluble faecal bile acids. (1988) (133)
Proliferative activity of rectal mucosa and soluble fecal bile acids in patients with normal colons and in patients with colonic polyps or cancer. (1988) (132)
Cellular toxicity of fecal water depends on diet. (1987) (128)
Initiation and promotion of colonic aberrant crypt foci in rats by 5-hydroxymethyl-2-furaldehyde in thermolyzed sucrose. (1993) (125)
Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo. (1967) (111)
Comparison of the dose- and timesurvival curves for normal hematopoietic and lymphoma colony-forming cells exposed to vinblastine, vincristine, arabinosylcytosine, and amethopterin. (1969) (105)
Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat. (1990) (101)
Diet, aberrant crypt foci and colorectal cancer. (1993) (100)
Comparison of the Fecal Microflora in Rural Japanese and Urban Canadians (1986) (99)
Effect of calcium supplementation on mucosal cell proliferation in high risk patients for colon cancer. (1989) (94)
IN VITRO PRODUCTION OF COLONY‐STIMULATING ACTIVITY. I. EXPOSURE OF MOUSE PERITONEAL CELLS TO ENDOTOXIN (1974) (93)
Toxicity of glyoxals--role of oxidative stress, metabolic detoxification and thiamine deficiency. (2003) (90)
Structures of fecapentaenes, the mutagens of bacterial origin isolated from human feces. (1983) (88)
Comparison of the sensitivity of hematopoietic colony-forming cells in different proliferative states to 5-fluorouracil. (1967) (87)
Fructose and carbonyl metabolites as endogenous toxins. (2009) (86)
Nuclear aberrations as a short-term test for genotoxicity to the colon: evaluation of nineteen agents in mice. (1983) (86)
Insulin resistance and promotion of aberrant crypt foci in the colons of rats on a high-fat diet. (1997) (84)
The biosynthesis of protamine during spermatogenesis of the mouse: Extraction, partial characterization, and site of synthesis (1971) (83)
Histone synthesis and replacement during spermatogenesis in the mouse. (1977) (81)
Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein. (1992) (80)
Recent hypotheses for the origin of colon cancer. (1987) (78)
Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats. (2003) (75)
Aberrant crypt foci and microadenoma as markers for colon cancer. (1992) (75)
The effect of dietary ascorbic acid and α-tocopherol on fecal mutagenicity (1982) (73)
Effect of dietary calcium and cholic acid on the proliferative indices of murine coionic epithelium (1986) (71)
Comparison of the sensitivity of hematopoietic colony-forming cells in different proliferative states to vinblastine. (1967) (71)
A Convenient 137Cs Unit for Irradiating Cell Suspensions and Small Laboratory Animals (1965) (68)
Sucrose enhancement of the early steps of colon carcinogenesis in mice. (1993) (66)
Reevaluation of nitrate and nitrite levels in the human intestine. (1981) (59)
Chromosomal abnormalities and the morphology of mouse sperm heads. (1975) (58)
Physical characteristics of mouse sperm nuclei. (1976) (58)
Colonic fermentation and markers of colorectal-cancer risk. (1992) (57)
On the mechanism of the lethal action of 5-fluorouracil on mouse L cells. (1968) (56)
Colonic protein fermentation and promotion of colon carcinogenesis by thermolyzed casein. (1995) (56)
Studies on the persistence of methotrexate, cytosine arabinoside, and leucovorin in serum of mice. (1969) (56)
Early histopathologic events to evolution of colon cancer in C57BL/6 and CF1 mice treated with 1,2-dimethylhydrazine. (1983) (55)
A preliminary investigation of the metabolism of dietary phenolics in humans (1983) (53)
Comparison of the effects of 1,2-dimethylhydrazine and cyclophosphamide on micronucleus incidence in bone marrow and colon. (1983) (50)
Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to tritiated thymidine. (1965) (49)
Sensitivity of L Cells in Exponential and Stationary Phase to 5-Fluorouracil (1967) (48)
Volatile N-nitrosamines in the urine of normal donors and of bladder cancer patients. (1979) (47)
Strategies for dietary intervention studies in colon cancer (1981) (46)
Hematological recovery in the mouse following single doses of gamma radiation and cyclophosphamide. (1968) (46)
Effects of cannabinoids on sperm morphology. (1979) (46)
Aberrant crypts, putative precancerous lesions, in the study of the role of diet in the aetiology of colon cancer. (1989) (46)
Wheat-bran and oat-bran supplements' effects on blood lipids and lipoproteins. (1992) (44)
Aberrant crypt focus promotion and glucose intolerance: correlation in the rat across diets differing in fat, n-3 fatty acids and energy. (1998) (44)
Toxicity of orally administered fat to the colonic epithelium of mice. (1985) (44)
Synergistic action of cyclophosphamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on a transplanted murine lymphoma. (1968) (42)
Differences in glyoxal and methylglyoxal metabolism determine cellular susceptibility to protein carbonylation and cytotoxicity. (2011) (41)
Detection of nuclear anomalies in the colonic epithelium of the mouse. (1985) (41)
THE LINEAR ENERGY TRANSFER DISTRIBUTIONS RESULTING FROM PRIMARY AND SCATTERED X-RAYS AND GAMMA RAYS WITH PRIMARY HVL'S FROM 1.25 MM CU TO 11 MM PB. (1963) (40)
Studies relating to a fecal mutagen. (1980) (38)
The dependence of depth dose on focal skin distance. (1958) (38)
Glycoprotein glycosyltransferase levels during spermatogenesis in mice. (1974) (38)
Marginal dietary thiamin deficiency induces the formation of colonic aberrant crypt foci (ACF) in rats. (2003) (38)
Proliferative activity of murine mammary epithelium as affected by dietary fat and calcium. (1987) (37)
LOCAL PLASMA VOLUME AND VASCULAR PERMEABILITY OF RABBIT SKIN AFTER IRRADIATION. (1964) (36)
Thermally oxidized dietary fat and colon carcinogenesis in rodents. (1998) (36)
DISSEMINATION AND GROWTH OF TRANSPLANTED ISOLOGOUS MURINE LYMPHOMA CELLS. (1964) (36)
THE RADIATION SENSITIVITY OF TRANSPLANTED LYMPHOMA CELLS AS DETERMINED BY THE SPLEEN COLONY METHOD. (1964) (35)
Natural history of aberrant crypt foci (1996) (35)
Gastrointestinal cancer : endogenous factors (1981) (35)
Increase by deoxycholic acid of the colonic nuclear damage induced by known carcinogens in C57BL/6J mice. (1986) (34)
Characterization of cytotoxic steroids in human faeces and their putative role in the etiology of human colonic cancer. (1986) (34)
On distribution of different fecapentaenes, the fecal mutagens, in the human population. (1984) (33)
Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells of mice to vinblastine administered in vivo. (1966) (32)
Dietary factors affecting the proliferation of epithelial cells in the mouse colon. (1988) (30)
Inhibition of rat mammary tumorigenesis by dietary cholesterol. (1996) (30)
Effect of dietary calcium and cholic acid on the proliferative indices of murine colonic epithelium. (1986) (30)
A model for the action of vinblastine in vivo. (1966) (30)
Serum Endotoxins and Flagellin and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort (2016) (29)
The Association between Glyceraldehyde-Derived Advanced Glycation End-Products and Colorectal Cancer Risk (2015) (29)
Mutagenicity of different fractions of extracts of human feces. (1983) (29)
Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. (2011) (29)
Damaging effect of dietary components to colon epithelial cells in vivo: effect of mutagenic heterocyclic amines. (1984) (29)
An in vitro assay for growth-inhibiting activity of vinblastine. (1965) (28)
The colonic protein fermentation and insulin resistance hypotheses for colon cancer etiology: experimental tests using precursor lesions. (1996) (27)
Natural history of aberrant crypt foci. A surgical approach. (1996) (27)
Reduction of colony-forming cell sensitivity to arabinosylcytosine by halothane anesthesia. (1970) (27)
Radiation induction of mutations affecting sperm morphology in mice. (1983) (26)
THE SPECTRA OF X RAYS SCATTERED IN LOW ATOMIC NUMBER MATERIALS (1960) (26)
Survival of Mice Bearing a Transplanted Syngeneic Lymphoma Following Treatment With Cyclophosphamide, 5-Fiuorouracil, or 1,3-Bis(2-chloroethyl)-1-nitrosourea (1967) (25)
The effects of partial thiamin deficiency and oxidative stress (i.e., glyoxal and methylglyoxal) on the levels of α‐oxoaldehyde plasma protein adducts in Fischer 344 rats (2005) (25)
Incorporation of 5-iododeoxyuridine 1311 in spontaneous C3H mouse mammary tumours. (1962) (22)
Absence of volatile nitrosamines in human feces. (1981) (21)
[Altered sensitivity of hematopoietic stem cells to 5-fluorouracil (NSC-19893) following endotoxin (NSC-189681), cyclophosphamide (NSC-26271), or irradiation]. (1974) (21)
Polyethylene glycol reduces inflammation and aberrant crypt foci in carcinogen-initiated rats. (2005) (20)
The effect of dietary ascorbic acid and alpha-tocopherol on fecal mutagenicity. (1982) (19)
A thermolyzed diet increases oxidative stress, plasma alpha-aldehydes and colonic inflammation in the rat. (2007) (19)
Rapid quantitation of thermal oxidation products in fats and oils by 1H-NMR spectroscopy. (1998) (19)
Counterpoint: From animal models to prevention of colon cancer. Criteria for proceeding from preclinical studies and choice of models for prevention studies. (2003) (18)
Kinetics of Histone and Protamine Synthesis During Meiosis and Spermiogenesis in the Mouse * (2009) (17)
The action of chemotherapeutic agents at the cellular level and the effects of these agents on hematopoietic and lymphomatous tissue. (1967) (16)
Chemotherapy of the transplanted KHT fibrosarcoma in mice. (1972) (16)
Polyethylene glycol 8000 and colon carcinogenesis: inhibition in the F344 rat, promotion in the Min mouse. (2000) (16)
RESEARCH ON OCULAR EFFECTS PRODUCED BY THERMAL RADIATION (1966) (16)
Hepatocyte inflammation model for cytotoxicity research: fructose or glycolaldehyde as a source of endogenous toxins (2009) (16)
Biochemical changes as a result of increased fiber consumption (1984) (16)
Manipulation of fecal pH by dietary means. (1990) (15)
THE RADIATION SENSITIVITY OF TRANSPLANTED MURINE LYMPHOMA AS DETERMINED BY TWO DIFFERENT ASSAY METHODS. (1965) (15)
Human fecal fractions can produce nuclear damage in the colonic epithelial cells of mice. (1984) (15)
Dietary cholesterol inhibits the development of aberrant crypt foci in the colon. (1996) (15)
Genotoxicity of two fecal steroids in murine colonic epithelium assessed by the sister chromatid exchange technique. (1987) (14)
Quantitation of nuclear aberrations as a screen for agents damaging to mammary epithelium. (1986) (14)
Non-volatile N-nitroso compounds in human feces. (1978) (14)
Spermatogenesis in hybrid mice treated with oestrogen and testosterone. (1977) (14)
An empirical cellular approach to the improvement of cancer chemotherapy. (1969) (13)
Effects of sodium sulfate on fecal pH and proliferation of colonic mucosa in patients at high risk for colon cancer. (1990) (13)
A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation (2005) (13)
Endotoxin-induced sensitivity of hematopoietic stem cells to chemotherapeutic agents. (1972) (13)
Effect of high-fat and low-fiber meals on the cell proliferation activity of colorectal mucosa. (1991) (13)
Experimentally determined electron energy distribution produced by cobalt 60 gamma rays. (1955) (12)
Aberrant crypt foci in the detection of colon carcinogens. (1990) (11)
Sperm size abnormalities in homozygous and heterozygous In(5)9Rk mice. (1979) (11)
Ocular Effects of Near Infrared Laser Radiation for Safety Criteria (1972) (11)
Genetic control of the kinetics of mouse spermatogenesis. (1973) (11)
Marginal thiamine deficiency increases oxidative markers in the plasma and selected tissues in F344 rats (2007) (9)
What chemicals are responsible for colon cancer? (1986) (9)
Dehydroalanine and lysinoalanine in thermolyzed casein do not promote colon cancer in the rat. (2008) (9)
General structure of “fecapentaenes” — the mutagenic substances in human faeces (1982) (8)
Ocular Effects of Repetitive Laser Pulses (1972) (8)
Comparison of Monte Carlo calculations and experimental measurements of scattered radiation produced in a water phantom by primary radiations with half-value layers from 1.25 mm Cu to 11 mm Pb. (1962) (8)
Concanavalin A (NSC-143504): its action on experimental tumor cells and possible use in cancer chemotherapy. (1975) (8)
Survival of mice bearing a transplanted syngeneic lymphoma following treatment with cyclophosphamide, 5-fluorouracil, or 1,3-bis(2-chloroethyl)-1-nitrosourea. (1968) (7)
Dietary fiber and cancer: a supplement for intervention studies. (1985) (7)
Analysis and formation of nitrosamines in the human intestine. (1982) (7)
Risk factors for colorectal cancer in man induce aberrant crypt foci in rats: Preliminary findings (2015) (7)
The electronic determination of the size distribution of L-cell minicolonies. (1969) (7)
Spectral distribution of scattered radiation in a water phantom irradiated with cesium-137 gamma rays. (1962) (6)
Effects of cyclophosphamide(cy), 1,3-bis(2-cholroethyl)-1-nitrosourea (bcnu), vinblastine(vlb) and cytosine arabinoside(ara-c) on lymphoma cells from the spontaneous lymphoma of akr mice. Abstr. (1969) (6)
The Suppression by Cortisone of the Acute Local Radiation Reaction in the Rabbit Ear (1960) (6)
Induction and transmission of elevated levels of abnormally-shaped murine sperm. Abstr. (1976) (6)
A minicolony assay for the viability of mammalian cells in vitro. (1968) (6)
Transmission of radiation-induced elevations in abnormally-shaped murine sperm (1978) (6)
Monte Carlo Calculations on the Spectrum of Scattered Radiation Produced in Water by X-Ray Beams of Interest in Radiotherapy (1957) (5)
Fructose‐Derived Endogenous Toxins (2010) (5)
Diet-related factors in the origin of cancer of the large bowel--a molecular scientist's point of view. (1986) (5)
A CHO cell line resistant to deoxycholic acid. (1987) (5)
An analytical method for simple N-nitrosamides. (1982) (5)
SURVIVAL OF PATIENTS TREATED FOR CANCER OF THE BREAST, CERVIX, LUNG, AND UPPER RESPIRATORY TRACT AT THE ONTARIO CANCER INSTITUTE (TORONTO) FROM 1930 TO 1957. (1963) (5)
Possible mechanisms relating diet to colorectal cancer risk. (2002) (4)
A cellular approach to the chemotherapy of spontaneous leukemia of AKR mice. (1972) (4)
Endogenous toxins : diet, genetics, disease and treatment (2010) (4)
A strategy using short‐term assays to identify carcinogens that act in man (1978) (4)
Fluorescence angiography of chorioretinal burns. (1967) (4)
Effect of dietary fat levels on the susceptibility of colonic cells to nuclear-damaging agents. (1986) (3)
The effect of lowering faecal pH on the rate of proliferation of the normal colonic mucosa. (1992) (3)
Lipophilic substances in human faeces (1982) (3)
Chorioretinal burn: body temperature dependence. (1971) (3)
Role of body temperature in the definition of retinal burn threshold. (1971) (3)
Biomarkers of exposure to endogenous oxidative and aldehyde stress (2011) (3)
Long-Term Effects of Dietary Calcium on Risk Markers for Colon Cancer in Familial Polyposis Patients (1990) (2)
Report of group A of the American Cancer Society Research Workshop on Cancer and Nutrition: panel on human studies. (1993) (2)
Experimental approaches to colon cancer prevention in humans. (1988) (2)
Lifestyle, Endogenous Toxins, and Colorectal Cancer Risk (2010) (2)
Monte Carlo Calculations of the Scattering of X-Rays in Low Atomic Number Materials. (1956) (2)
Effect of dietary calcium on the toxicity of bile acid and orally administered fat to colonic epithelium. (1986) (2)
Studies of the Genetic Implications of Abnormal Spermatozoa (1976) (2)
Selective action of concanavalin a on transplanted tumors of the mouse. Abstr. (1971) (2)
Two in vivo assays for mutagenicity compared: The sperm abnormality and micronucleus assays (1978) (1)
Toxicity of dietary components to colonic mucosa in vivo. Abstr. (1983) (1)
Physical and chemical studies of sperm production. (1970) (1)
Promotion of Colonie Microadenoma Growth in Mice and Rats Fed Cooked Sugar or Cooked Casein and Fat1 (2006) (1)
Short-term tests and long-term prospects for colon cancer prevention (1990) (1)
Effect of dietary fibers on cholic acid induced cell proliferation in the colonic epithelium of C57BL/6J mice (1986) (1)
The concentration of bile acids in the fecal stream as a risk factor for colon cancer. (1986) (1)
Chemotherapy of a transplanted mouse sarcoma. Abstr. (1970) (1)
On the application of results from a model system to the treatment of leukemia in man. (1967) (1)
Power-Frequency Electromagnetic Fields and Exposure Geometry (2001) (1)
Insulin Promotion of Colon Tumors in (1996) (1)
EXPERIENCE WITH A REMOTELY CONNECTED TIME-SHARING COMPUTER TERMINAL. (1970) (1)
Point/Counterpoint Counterpoint: From Animal Models to Prevention of Colon Cancer. Criteria for Proceeding from Preclinical Studies and Choice of Models for Prevention Studies 1 (2003) (0)
EVALUATION OF EYE HAZARDS FROM NUCLEAR DETONATIONS. 1. RETINAL BURNS AND FLASHBLINDNESS (1969) (0)
Does cooked Western diet initiate colon carcinogenesis in rats (2008) (0)
Comprar Endogenous Toxins: Targets for Disease Treatment and Prevention | Thom Rooke | 9783527323630 | Wiley (2009) (0)
1025 The association between glyceraldehyde-derived advanced glycation end-products and colorectal cancer risk: A case-control study nested within the European prospective investigation into cancer and nutrition cohort (2015) (0)
The western diet, endogenous cytotoxin and genotoxin formation, a possible cause of carcinogenesis (2008) (0)
Nuclear aberration assay as an in vivo short-term test for colon carcinogens and cocarcinogens (1987) (0)
Approaches to understanding the relationship between diet and colon cancer. (1985) (0)
The radiosensitivity of murine lymphoma cells in vivo as determined by a splenic colony method. Abstr. (1963) (0)
The dissemination and growth of transplanted isologous murine lymphoma cells using the spleen colony method. Abstr. (1964) (0)
The effect of calcium on the pathogenicity of high fat diets to the colon. (1985) (0)
COMPARATIVE STUDY OF THE EFFECTS OF ULTRAVIOLET RADIATION ON THE EYE. Final Report, October 1, 1968--September 30, 1969. (1970) (0)
A STUDY OF THE PRODUCTION OF CHORIORENTINAL LESIONS BY THERMAL RADIATION. (1966) (0)
A model system for examining the action of anti-cancer agents at the cellular level in vivo. (1967) (0)
The suppression by cortisone of the acute local radiation in the rabbit ear. (1960) (0)
CELL PROTECTION BY ANESTHESIA (1971) (0)
A diet high in saturated fat and low in calcium is more detrimental to bone health of male Wistar rats than a fructose‐rich diet (2013) (0)
Absence of Volatile Nitrosamines in Human Feces1 (2006) (0)
Mice treated with 1,2-dimethylhydrazine. Abstr. (1983) (0)
Advances in Brief Polyethylene Glycol 8000 and Colon Carcinogenesis : Inhibition in the F 344 Rat , Promotion in the Min Mouse 1 (2000) (0)
The measurement of the effects of anti-cancer agents (1974) (0)
VolatileN-Nitrosaminesin the Urineof NormalDonorsand of Bladder Cancer Patients (1979) (0)
Inhibition of 1,2-dimethylhydrazine-induced colonic genotoxicity by dietary disulfiram. Abstr. (1982) (0)
Effects ofcalcium andpHon themucosal damage produced bydeoxycholic acid intheratcolon (1986) (0)
Cellular composition of fractions of mouse testis cells following velocity sedimentation separation. (1973) (0)
Abstract B34: Association of endogenous oxidative and aldehyde stress: Implications for studies of colon carcinogenesis (2010) (0)
Steps between diet and colon cancer. (1988) (0)
In search of human colon carcinogens: two approaches to their detection and identification. (1983) (0)

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What Schools Are Affiliated With William Robert Bruce?

William Robert Bruce is affiliated with the following schools:

University of Toronto