W. R. Wayne Martin
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(Suggest an Edit or Addition)W. R. Wayne Martin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. (1976) (2890)
- Pharmacology of opioids. (1983) (702)
- The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog. (1976) (479)
- Naltrexone, an antagonist for the treatment of heroin dependence. Effects in man. (1973) (353)
- The human pharmacology and abuse potential of N-allylnoroxymorphone (naloxone). (1967) (292)
- Methadone--a reevaluation. (1973) (257)
- Methods for evaluating addiction liability. (A) "Attitude" of opiate addicts toward opiate-like drugs. (B) a short-term "direct" addiction test. (1961) (253)
- Physiological parameters of morphine dependence in man--tolerance, early abstinence, protracted abstinence. (1969) (250)
- Opioid antagonists. (1967) (199)
- Opioid analgesics and antagonists (1990) (183)
- A comparative study of physiological and subjective effects of heroin and morphine administered intravenously in postaddicts. (1961) (165)
- Tolerance to and physical dependence on morphine in rats (1963) (154)
- Studies of the dependence-producing potential of the narcotic antagonist 2-cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (cyclazocine, WIN-20,740, ARC II-c-3). (1965) (131)
- A COMPARISON BETWEEN ACUTE AND CHRONIC PHYSICAL DEPENDENCE IN THE CHRONIC SPINAL DOG. (1964) (130)
- Effects of short‐ and long‐term administration of pentazocine in man (1970) (128)
- Antagonism of the subjective, behavioral, pupillary, and respiratory depressant effects of cyclazocine by naloxone (1968) (127)
- An experimental study in the treatment of narcotic addicts with cyclazocine (1966) (124)
- History and development of mixed opioid agonists, partial agonists and antagonists. (1979) (118)
- Antagonism of the convulsant effects of heroin, d-propoxyphene, meperidine, normeperidine and thebaine by naloxone in mice. (1975) (95)
- Demonstration of tolerance to and physical dependence of N-allylnormorphine (nalorphine). (1965) (82)
- Demonstration of tolerance and physical dependence in the dog following a short-term infusion of morphine. (1961) (82)
- Morphine physical dependence in the dog. (1974) (77)
- The effect of the narcotic antagonists naloxone, naltrexone and nalorphine on spinal cord C-fiber reflexes evoked by electrical stimulation or radiant heat. (1977) (76)
- Effects of morphine, nalorphine, cyclazocine, and naloxone on the flexor reflex. (1967) (68)
- Studies of the dependence‐producing properties of GPA‐1657, profadol, and propiram in man (1971) (66)
- The effect of a benzodiazepine antagonist, RO15-1788, in diazepam dependent rats. (1982) (65)
- Neuropharmacology and Neurochemistry of Subjective Effects, Analgesia, Tolerance, and Dependence Produced by Narcotic Analgesics (1977) (64)
- Diazepam and pentobarbital dependence in the rat. (1982) (63)
- The comparative binding characteristics of nicotinic ligands and their pharmacology (1988) (61)
- Suspected Chromium Picolinate‐Induced Rhabdomyolysis (1998) (61)
- The respiratory effects of morphine during a cycle of dependence. (1968) (56)
- Nature of nicotine binding to rat brain P2 fraction (1984) (50)
- Innervation of the spinal cord by sympathetic fibers (1980) (49)
- Chlorpromazine. III. The effects of chlorpromazine and chlorpromazine sulfoxide on vascular responses to L-epinephrine and levarterenol. (1960) (46)
- FACTORS INFLUENCING BRAIN AND TISSUE LEVELS OF TRYPTAMINE: SPECIES, DRUGS AND LESIONS (1975) (45)
- Physical dependence on diazepam and lorazepam in the dog. (1983) (45)
- Possible medullary kappa hyperalgesic mechanism. I. A new potential role for endogenous opioid peptides in pain perception. (1983) (45)
- Catecholamine and 17-hydroxycorticosteroid excretion during a cycle of morphine dependence in man. (1969) (43)
- AGONISTS AND ANTAGONISTS (2006) (42)
- Psychopathic State Inventory (PSI): development of a short test for measuring psychopathic states. (1980) (41)
- Sleep suppression induced by intravenous and intraventricular infusions of methoxamine in the dog (1977) (40)
- USE OF HINDLIMB REFLEXES OF THE CHRONIC SPINAL DOG FOR COMPARING ANALGESICS. (1964) (40)
- Opioid and nicotinic analgesic and hyperalgesic loci in the rat brain stem. (1992) (39)
- Liver disease in narcotic addicts I. The role of the drug (1968) (38)
- The Use of the Polaroid CU Camera in Pupillography (1967) (37)
- Hyperalgesic and analgesic actions of morphine, U50-488, naltrexone, and (−)-lobeline in the rat brainstem (1994) (37)
- Aspects of the psychopathology and pathophysiology of addiction. (1977) (37)
- Assessment of the Abuse Potential of Narcotic Analgesics in Animals (1977) (37)
- A sustained release depot for narcotic antagonists. (1974) (36)
- Gender differences in adolescent psychiatric outpatient substance use: associated behaviors and feelings. (1997) (36)
- XVI. A homeostatic and redundancy theory of tolerance to and dependence on narcotic analgesics. (1968) (36)
- Use of the chronic spinal dog for the assessment of the abuse potentiality and utility of narcotic analgesics and narcotic antagonists (1978) (34)
- Interaction between nicotine and endogenous opioid mechanisms in the unanesthetized dog (1982) (32)
- An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog. (1983) (30)
- Precipitated abstinence in orally dosed benzodiazepine-dependent dogs. (1990) (29)
- Factors regulating oral consumption of an opioid (etonitazene) by morphine-addicted rats (1963) (29)
- Precipitated abstinence in the diazepam-dependent rat (1993) (27)
- Antagonism of the spinal cord effects of morphine and cyclazocine by naloxone and thebaine. (1967) (26)
- The Evolution of Concepts (2011) (25)
- A pharmacological study on the Renshaw cell. (1960) (24)
- Subjective and physiologic effects of morphine, pentobarbital, and meprobamate (1976) (23)
- Studies of tryptamine and lysergic acid diethylamide (LSD) on cutaneous C-fiber and polysynaptic reflexes in the cat. (1974) (23)
- Effects of infused tryptamine in man (2004) (22)
- Chlorpromazine. I. The action of chlorpromazine and related phenothiazines on the EEG and its activation. (1958) (22)
- Comparative effects of codeine and morphine in man. (1967) (22)
- Actions of methoxamine and tryptamine and their interactions with cyproheptadine and phenoxybenzamine on cat spinal cord segmental reflexes. (1976) (22)
- Pharmacology and Classification of LSD-like Hallucinogens (1977) (22)
- Antagonism of the effects of pentobarbital in the chronic spinal dog by naltrexone. (1977) (21)
- Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs. (1988) (21)
- The identification of LSD-like hallucinogens using the chronic spinal dog. (1978) (21)
- A comparison of fentanyl, droperidol, and morphine (1965) (21)
- Binding characteristics of (−)- and (+)-nicotine to the rat brain P2 fraction (1985) (21)
- Morphine, sedative/hypnotic and alcohol dependence (1977) (21)
- The Pathophysiology of Morphine Dependence and its Treatment with Opioid Antagonists (1968) (21)
- Addiction liability of an isoquinoline analgesic, 1‐(p‐chlorophenethyl)‐2‐methyl‐6,7‐dimethoxy‐1,2,3,4‐tetrahydroisoquinoline (1961) (20)
- Brain levels of tryptamine (2004) (20)
- INTERACTIONS BETWEEN NALORPHINE AND MORPHINE IN THE DECEREBRATE CAT (1962) (19)
- Assessment of the Abuse Potentiality of Amphetamines and LSD-Like Hallucinogens in Man and its Relationship to Basic Animal Assessment Programs (1973) (19)
- Lack of antiemetic effects of delta9-tetrahydrocannabinol in apomorphine-induced emesis in the dog. (1978) (19)
- Opioid and nicotinic medullary hyperalgesic influences in the decerebrated rat (1988) (18)
- A pharmacologic comparison of 3,4-methylenedioxyamphetamine and LSD in the chronic spinal dog. (1977) (18)
- Pharmacologic characteristics of a medullary hyperalgesic center. (1993) (18)
- Comparison of graded single intramuscular doses of morphine and pentobarbital in man (1974) (17)
- Psychometric comparisons of sociopathic and psychopathological behaviors of alcoholics and drug abusers versus a low drug use control population. (1980) (17)
- Medullary kappa hyperalgesic mechanisms II. The effects of ethylketazocine administered into the fourth cerebral ventricle of the conscious dog. (1983) (17)
- A comparison of fentanyl, droperidol, and morphine. (1966) (17)
- N-desmethyldiazepam physical dependence in dogs. (1985) (17)
- Sigma effects of nalorphine in the chronic spinal dog. (1976) (17)
- Structure-activity relationships of some pyridine, piperidine, and pyrrolidine analogues for enhancing and inhibiting the binding of (+/-)-[3H]nicotine to the rat brain P2 preparation. (1985) (17)
- Physiologic evidence for descending tryptaminergic pathways in the spinal cord. (1976) (16)
- The effect of L-tryptophan on spinal cord C-fiber reflexes. (1976) (15)
- An analysis of naltrexone precipitated abstinence in morphine-dependent chronic spinal dogs. (1987) (15)
- General Problems of Drug Abuse and Drug Dependence (1977) (15)
- Cyclazocine, an Adjunct in the Treatment of Narcotic Addiction (1967) (14)
- A pharmacologic comparison of 2,5-dimethoxyamphetamine and LSD in the chronic spinal dog (1977) (14)
- Comparison of the effects of single Doses of morphine and thebaine on body temperature, activity, and brain and heart levels of catecholamines and serotonin (1962) (14)
- Effect of the chronic dose of diazepam on the intensity and characteristics of the precipitated abstinence syndrome in the dog. (1993) (14)
- Pharmacological studies of spinal cord adrenergic and cholinergic mechanisms and their relation to physical dependence on morphine (1967) (14)
- Measurement of psychopathy as a state. (1978) (13)
- Effects of naloxone and fentanyl in acutely decerebrated dogs. (1982) (13)
- A comparison of the physical dependence inducing properties of flunitrazepam and diazepam (1991) (13)
- Multiple nicotine binding sites in rat brain P2 fraction. (1983) (13)
- The action of tryptamine on the dog spinal cord and its relationship to the agonistic actions of LSD-like psychotogens (2004) (12)
- New and Experimental Therapeutic Roles for Naloxone and Related Opioid Antagonists (2012) (12)
- Drug Dependence of Specific Opiate Antagonist Type (1970) (11)
- Dependence-producing properties of alprazolam in the dog (1990) (11)
- Responses of the flexor reflex to LSD, tryptamine, 5-hydroxytryptophan, methoxamine, and d-amphetamine in acute and chronic spinal rats (1977) (11)
- Chlorpromazine II. The effects of chlorpromazine on evoked potentials in the midbrain reticular formation. (1958) (11)
- Cardiovascular and respiratory effects of an opioid kappa agonist ethylketazocine and sigma agonist N-allylnormetazocine in acutely decerebrated dogs (1989) (11)
- Tolerance to and physical dependence on N-allylnormetazocine (NANM) in chronic spinal dogs. (1980) (11)
- Assessment of the dependence‐producing properties of dihydrocodeinone and codoxime (1967) (11)
- Analgesic actions of dynorphin A(1–13) antiserum in the rat brain stem (1992) (10)
- Thermally evoked tail avoidance reflex: Input-output relationships and their modulation (1992) (10)
- Mechanisms involved in the respiratory depressant actions of nicotine in anesthetized rats (1989) (10)
- Flumazenil oral absorption in dogs (1988) (10)
- THE MODE OF ACTION OF LSD-LIKE HALLUCINOGENS AND THEIR IDENTIFICATION (1978) (10)
- Some Clinical Aspects of Addiction to Narcotic Analgesics (1965) (9)
- Chronic administration of and dependence on halazepam, diazepam, and nordiazepam in the dog. (1991) (9)
- The effect of addiction to and abstinence from morphine on rat tissue catecholamine and serotonin levels (1963) (9)
- Interactions between norepinephrine antagonists and potentiators (chlorpromazine, chlorpromazine sulfoxide and imipramine) and sympathetic amines (amphetamine and methoxamine) on the flexor reflex of the chronic spinal dog. (1968) (9)
- Stereospecificity of 2-methylpiperidine binding to a nicotinic up-regulatory site in the rat brain P2 preparation. (1985) (9)
- The inhibition of food intake in the dog by LDS, mescaline, psilocin, d-amphetamine and phenylisopropylamine derivatives. (1979) (9)
- Realistic goals for antagonist therapy. (1975) (9)
- Chemotherapy of Narcotic Addiction (1977) (8)
- Single dose and cross tolerance studies of beta-phenethylamine, d-amphetamine and LSD in the chronic spinal dog. (1978) (8)
- A comparative study of the effect of drugs on activating and vasomotor responses evoked by midbrain stimulation: Atropine, pentobarbital, chlorpromazine and chlorpromazine sulfoxide (1960) (8)
- LSD and tryptamine effects on sleep/wakefulness and electrocorticogram patterns in intact cats (1978) (8)
- A study of the peripheral and central actions of dibromopyruvic acid. (1958) (8)
- Relationship of CNS tryptaminergic processes and the action of LSD-like hallucinogens (1986) (8)
- Development of a combined high-performance liquid chromatographic-fluorometric quantitative assay for enkephalins (1980) (7)
- The Evolution of Concepts of Opioid Receptors (1988) (7)
- Actions of amphetamine and antagonists on pupil diameter in the chronic sympathectomized dog (1977) (7)
- Noradrenergic action of amphetamine following degeneration of descending monoaminergic fibers in the spinal cord (2004) (7)
- Opiate Dependence in Women (1980) (7)
- Multiple Nicotinic Receptors: Nicotinic Ligands with Different Specificities (1987) (7)
- Effects of central nervous system depressants on inhibition and facilitation of the patellar reflex. (1960) (7)
- Benzodiazepine antagonist, CGS-8216, in diazepam- or pentobarbital-dependent and non-dependent rats. (1986) (6)
- Role of agonist-antagonist analgesics in medicine. (1985) (6)
- Use of gastric fistula rats for the study of sedative, hypnotic and antianxiety drugs. (1981) (6)
- Thoughts about the relevance of neurochemistry, neurophysiology and neuropsychopharmacology to the social problems of drug abuse. (1983) (5)
- Phenomenology and theoretical basis of tolerance and dependence. (1984) (5)
- A pharmacological comparison of 3-methoxy-4,5-methylenedioxyamphetamine and LSD in the dog. (1978) (5)
- Tryptamine in the brain and spinal cord: its role in the LSD response. (1976) (5)
- The effects of naltrexone in the chronic spinal dog and acute spinal cat; possible interaction with naturally-occurring morphine-like agonists. (1976) (5)
- Brain-plasma distribution of free and total benzodiazepines in dogs physically dependent on different doses of diazepa (1995) (5)
- Physical dependence of benzodiazepines in the rat and dog. (1986) (5)
- Synthesis and binding activity of 4-azanicotine (1991) (5)
- Relationship of Biological Influences on the Subjective States of Addicts (1984) (5)
- An analysis of naltrexone and naloxone's possible agonistic actions in the dog. (1985) (4)
- The effects of flumazenil-precipitated abstinence on the pharmacokinetics of chronic oxazepam in dogs (1990) (4)
- The pharmacology of thebaine in the chronic spinal dog. (1978) (4)
- Distribution of diazepam, nordiazepam, and oxazepam between brain extraneuronal space, brain tissue, plasma, and cerebrospinal fluid in diazepam and nordiazepam dependent dogs (2005) (4)
- The demonstration of tryptamine in regional perfusates of the dog brain (1974) (4)
- SYMPATHETIC INNERVATION OF THE SPINAL CORD (1979) (4)
- Fourth ventricle effects of nicotine, 2-methylpiperidine and cytisine in dogs (1986) (4)
- Clinical evidence for different narcotic receptors and relevance for the clinician. (1986) (4)
- D – Analgesic and Antipyretic Drugs (1963) (4)
- Transcallosally evoked potentials and the EEG in the decerebrate dog: actions of tryptaminergic, dopaminergic and adrenergic agonists. (1977) (3)
- Physiologic parameters of morphine dependence in man--tolerance, early abstinence, protracted abstinence. (1970) (3)
- The possible role of tryptamine in brain function and its relationship to the actions of LSD-like hallucinogens. (1974) (3)
- The absence of an effect of L-tryptophan on the C-fiber reflex in the chronic spinal cat. (1977) (3)
- Cross tolerance to tryptamine in the LSD tolerant dog (2004) (3)
- Emerging concepts concerning drug abuse. (1980) (2)
- Skin conductance responses to hypercapnia in man during a cycle of addiction to morphine (2004) (2)
- Pharmacokinetics and metabolism of halazepam in naive and dependent dogs (1991) (2)
- Amphetamine, psychotogen, and marihuana dependence (1977) (2)
- Neurochemical evidence for tryptaminergic ascending and descending pathways in the spinal cord of the dog (1975) (2)
- A method for bioassay of physical dependence on sedative drugs in dog (1976) (2)
- A history of the development of narcotic antagonists for the treatment of narcotic addiction. (1978) (1)
- Treatment of heroin dependence with naltrexone. (1975) (1)
- XXIX. The basis and possible utility of the use of opioid antagonists in the ambulatory treatment of the addict. (1968) (1)
- Analgesic actions of local anesthetics and cobalt chloride in the rat brain stem (1992) (1)
- Pharmacologic factors in relapse and the possible use of the narcotic antagonists in treatment. (1966) (1)
- Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog (2004) (1)
- [Action of mephenesin on Renshaw's cells]. (1957) (0)
- Dystonia. Volume 94, Advances in Neurology. 2004. Edited by Stanley Fahn, Mark Hallett, Mahlon R. DeLong. Published by Lippincott Williams and Wilkins, Philadelphia. 312 pages. C$220 approx. (2004) (0)
- Benzodiazepine dependence studies in rodents. (1980) (0)
- The nature of opioid and LSD receptors: structural activity relationship implications. (1978) (0)
- Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs (1993) (0)
- STRUCTURE-ACTIVITY RELATIONSHIPS OF SOME PYRIDINE, PIPERIDINE, AND PYRROLIDINE ANALOGS FOR ENHANCING AND INHIBITING THE BINDING OF (.+-.)-(3H)NICOTINE TO THE RAT BRAIN P2 PREPARATION (1985) (0)
- Parkinson's Disease and Parkinsonism in the Elderly. 2000. Edited by Jolyon Meara, William Koller. Published by Cambridge University Press. 251 pages. C$73.42 approx. (2001) (0)
- Drug effects on interneurones: effects of central nervous system depressants on spinal cord reflexes. (1959) (0)
- Actions of 2-methylpiperidine (MP) and its interactions with (-)-nicotine (N) in the dog and rat (1986) (0)
- Drug abuse strategies. (1990) (0)
- Tolerance and Physical Dependence (1989) (0)
- A steric theory of opioid agonists, antagonists, agonist-antagonists, and partial agonists. (1984) (0)
- PET AND NMR . Series: Neurology and Neurobiology, Volume 21. Edited by Leontino Battistin and Franz Gerstenbrand. Published by Alan R. Liss, Inc., New York, 518 pages. $119Cdn approx. (1988) (0)
- Synthesis and Binding Activity of 4-Azanicotine. (1991) (0)
- Tourette Syndrome: Genetics, Neurobiology, and Treatment. Advances in Neurology, Volume 58. 1992. Edited by N. Chase Thomas, J. Friedhoff Arnold, J. Cohen Donald. Published by Raven Press. 399 pages. $138.00 Cdn. (1993) (0)
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