Walter Birchmeier
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(Suggest an Edit or Addition)Walter Birchmeier's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Functional interaction of β-catenin with the transcription factor LEF-1 (1996) (2651)
- Met, metastasis, motility and more (2003) (2460)
- A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome (2005) (2368)
- E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells (1991) (1625)
- Wnt signalling and its impact on development and cancer (2008) (1524)
- Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. (1998) (1300)
- β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin (2001) (1296)
- Functional interaction of beta-catenin with the transcription factor LEF-1. (1996) (1258)
- Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. (1994) (1111)
- Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. (2005) (1085)
- Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors (2002) (1082)
- Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion (1989) (1018)
- Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene (1993) (963)
- Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex (2002) (857)
- Targeting MET in cancer: rationale and progress (2012) (837)
- Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy (2004) (790)
- Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells (1990) (710)
- E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton (1994) (685)
- Requirement for beta-catenin in anterior-posterior axis formation in mice. (2000) (662)
- Wnt signaling in stem and cancer stem cells. (2013) (604)
- Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. (2010) (591)
- Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. (1992) (587)
- Balancing cell adhesion and Wnt signaling, the key role of β-catenin (2006) (581)
- Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. (2008) (576)
- Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis (1996) (574)
- New aspects of Wnt signaling pathways in higher vertebrates. (2001) (569)
- Targeting MET in cancer: rationale and progress (2012) (548)
- E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. (1991) (544)
- Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling (2008) (532)
- beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. (2003) (515)
- Hot papers in cell biology - J. Behrens, J.P. von Kries, M. Kuehl, L. Bruhn, D. Wedlich, R. Grosschedl, W. Birchmeier: "Functional interaction of beta-catenin with the transcription factor LEF-1" - Comments by Walter Birchmeier (1999) (475)
- Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. (1993) (461)
- MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis (2009) (460)
- E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. (1993) (447)
- Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. (2006) (428)
- The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells (1993) (417)
- Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling (2006) (376)
- Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response (2003) (362)
- Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses (2000) (351)
- Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. (2004) (350)
- Inhibitory action of transforming growth factor beta on endothelial cells. (1987) (331)
- Hepatocyte growth factor/scatter factor induces a variety of tissue- specific morphogenic programs in epithelial cells (1995) (327)
- The role of Axin2 in calvarial morphogenesis and craniosynostosis (2005) (325)
- β-Catenin Is Required for Specification of Proximal/Distal Cell Fate during Lung Morphogenesis* (2003) (323)
- Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland (1995) (320)
- c-Met is essential for wound healing in the skin (2007) (308)
- Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. (2002) (302)
- Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. (2005) (301)
- E‐cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming (2011) (300)
- E-cadherin gene mutations in human gastric carcinoma cell lines. (1994) (299)
- Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly (2003) (292)
- Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin (1985) (291)
- Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. (2009) (289)
- Transforming growth factor-beta inhibits endothelial cell proliferation. (1986) (282)
- Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation (2004) (282)
- Stress fiber sarcomeres of fibroblasts are contractile (1980) (277)
- Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo (2000) (277)
- Epithelial-mesenchymal transitions in cancer progression. (1996) (275)
- Rap1 Regulates the Formation of E-Cadherin-Based Cell-Cell Contacts (2004) (267)
- How to make tubes: signaling by the Met receptor tyrosine kinase. (2003) (248)
- Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. (2001) (236)
- The tyrosine phosphatase Shp2 in development and cancer. (2010) (233)
- V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift (1995) (230)
- Molecular aspects of mesenchymal-epithelial interactions. (1993) (230)
- Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase (2018) (229)
- Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. (2001) (229)
- Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. (2008) (228)
- Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. (2006) (227)
- A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. (1992) (225)
- Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation (2006) (224)
- The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer. (2006) (213)
- Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility (1999) (212)
- The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. (1991) (211)
- On the mechanism of ATP-induced shape changes in the human erythrocyte membranes: the role of ATP (1977) (198)
- Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis (2007) (195)
- Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. (2003) (195)
- β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation (2003) (193)
- Down‐regulation of E‐cadherin expression in madin darby canine kidney (MDCK) cells inside tumors of nude mice (1991) (189)
- Hot spots in β-catenin for interactions with LEF-1, conductin and APC (2000) (188)
- E-cadherin as a tumor (invasion) suppressor gene. (1995) (182)
- Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking (2008) (180)
- Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency. (2012) (174)
- Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation (2001) (173)
- The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras. (1994) (172)
- Deletion of β-catenin impairs T cell development (2003) (169)
- The ankyrin repeat protein Diversin recruits Casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling (2002) (165)
- Prognostic value of E‐cadherin expression in 413 gastric carcinomas (1996) (164)
- Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo. (1995) (156)
- Evidence for the identy of human scatter factor and human hepatocyte growth factor. (1991) (156)
- Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. (2006) (156)
- Mechanisms Identified in the Transcriptional Control of Epithelial Gene Expression (*) (1996) (155)
- Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. (2003) (153)
- Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas. (1994) (152)
- Cell-cell interaction and polarity of epithelial cells: Specific perturbation using a monoclonal antibody (1983) (152)
- Reconstitution of Mammary Gland Development In Vitro: Requirement of c-met and c-erbB2 Signaling for Branching and Alveolar Morphogenesis (1998) (150)
- Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL* (2000) (150)
- Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. (2007) (149)
- New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals (2015) (145)
- &bgr;-Catenin Downregulation Is Required for Adaptive Cardiac Remodeling (2007) (138)
- Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. (1994) (136)
- A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential. (2009) (130)
- Role of morphogenetic factors in metastasis of mammary carcinoma cells (1998) (126)
- Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. (1994) (123)
- Multiple roles of mesenchymal β-catenin during murine limb patterning (2006) (122)
- Sustained epithelial β-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation (2008) (120)
- A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. (2016) (119)
- The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif (2001) (117)
- Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. (1995) (115)
- Cell adhesion in invasion and metastasis. (1992) (114)
- Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors. (2017) (109)
- The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. (2002) (107)
- Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas. (1993) (106)
- Motogenic and morphogenic activity of epithelial receptor tyrosine kinases (1996) (105)
- Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo (1998) (105)
- The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development (2009) (104)
- Cytoplasmic aspartate aminotransferase: syncatalytic sulfhydryl group modification. (1973) (103)
- In vivo distribution and turnover of fluorescently labeled actin microinjected into human fibroblasts. (1979) (103)
- Requirement for β-Catenin in Anterior-Posterior Axis Formation in Mice (2000) (101)
- Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine (2014) (100)
- Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo. (2018) (100)
- Monoclonal antibodies inhibit the adhesion of mouse B 16 melanoma cells in vitro and block lung metastasis in vivo. (1983) (99)
- Expression of E-cadherin and catenins in invasive mammary carcinomas. (1997) (97)
- Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells (2012) (96)
- Wnt signaling in stem and cancer stem cells. (2010) (93)
- Immunohistological analysis of E-cadherin, α-, β- and γ-catenin expression in colorectal cancer: implications for cell adhesion and signaling (1999) (93)
- Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas. (1995) (93)
- Microinjection of fluorescently labeled proteins into living cells with emphasis on cytoskeletal proteins. (1982) (92)
- Adherens junction proteins in tumour progression. (1995) (91)
- Deletion of beta-catenin impairs T cell development. (2003) (91)
- Multiple roles of mesenchymal beta-catenin during murine limb patterning. (2006) (90)
- Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons. (2007) (88)
- Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met. (1993) (85)
- Negative Regulation of Ros Receptor Tyrosine Kinase Signaling (2001) (85)
- Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients (2020) (84)
- Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells (1993) (83)
- Wnt/β‐catenin signalling induces MLL to create epigenetic changes in salivary gland tumours (2013) (82)
- The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway (2004) (80)
- Selection of Multipotent Stem Cells during Morphogenesis of Small Intestinal Crypts of Lieberkühn Is Perturbed by Stimulation of Lef-1/β-Catenin Signaling* (2002) (79)
- Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination (2014) (79)
- Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells (2010) (79)
- Hot spots in beta-catenin for interactions with LEF-1, conductin and APC. (2000) (78)
- Dominant and recessive genes involved in tumor cell invasion. (1991) (76)
- E-Cadherin in human brain tumours: loss of immunoreactivity in malignant meningiomas (1998) (75)
- Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain. (2019) (74)
- Deletion of the E‐cadherin gene in hepatitis B virus–positive chinese hepatocellular carcinomas (1993) (73)
- The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis (2018) (73)
- Diversin regulates heart formation and gastrulation movements in development (2006) (72)
- Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo (2007) (69)
- Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells. (1997) (67)
- Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways (2014) (66)
- The transcriptional repressor Glis2 is a novel binding partner for p120 catenin. (2007) (66)
- The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells (2004) (66)
- Epithelial-mesenchymal transitions in development and tumor progression. (1995) (65)
- Combined Wnt/β-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome. (2013) (64)
- New surface component of fibroblast's focal contacts identified by a monoclonal antibody (1982) (64)
- The impact of c‐met/scatter factor receptor on dendritic cell migration (2002) (64)
- Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF‐dependent transcription in medulloblastomas (2007) (61)
- Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo (2015) (61)
- Long-term, multilineage hematopoiesis occurs in the combined absence of -catenin and -catenin (2007) (61)
- Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development (2013) (59)
- Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts. (1980) (59)
- Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas (2004) (58)
- Molecular characteristics of HGF-SF and its role in cell motility and invasion. (1993) (58)
- Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism. (2006) (58)
- BCL9-2 promotes early stages of intestinal tumor progression. (2011) (57)
- Epithelial differentiation and the control of metastasis in carcinomas. (1996) (56)
- The role of E-cadherin and scatter factor in tumor invasion and cell motility. (1991) (56)
- E-cadherin as an invasion suppressor. (1995) (56)
- Control of cell locomotion: perturbation with an antibody directed against specific glycoproteins (1985) (56)
- Hepatocyte growth factor/scatter factor (HGF/SF) signals via the STAT3/APRF transcription factor in human hepatoma cells and hepatocytes (1997) (55)
- Monoclonal antibodies which prevent experimental lung metastases (1984) (54)
- Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling. (1999) (53)
- Monoclonal antibodies that prevent adhesion of B 16 melanoma cells and reduce metastases in mice: crossreaction with human tumor cells. (1983) (52)
- Interaction of integral and peripheral membrane proteins: affinity labeling of yeast cytochrome oxidase by modified yeast cytochrome c. (1976) (52)
- Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis (2013) (50)
- Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin. (2012) (49)
- Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling (2009) (48)
- Analysis of the E‐cadherin and P‐cadherin promoters in murine keratinocyte cell lines from different stages of mouse skin carcinogenesis (1997) (48)
- Attempts to Understand Metastasis Formation I (1996) (47)
- The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42 (2007) (46)
- Cytoskeleton structure and function (1984) (45)
- Monoclonal antibodies NORM-1 and NORM-2 induce more normal behavior of tumor cells in vitro and reduce tumor growth in vivo (1985) (45)
- Orchestrating Wnt signalling for metabolic liver zonation (2016) (44)
- Transforming growth factor beta as a potent promoter in two-stage BALB/c 3T3 cell transformation. (1988) (44)
- Chemical evidence for syncatalytic conformational changes in aspartate aminotransferase (1971) (41)
- RNF4-Dependent Oncogene Activation by Protein Stabilization (2016) (40)
- Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer (2005) (40)
- Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. (2019) (39)
- Characterization of the Scatter Factor/Hepatocyte Growth Factor Gene Promoter (1995) (39)
- Tracing tumorigenesis in a solid tumor model at single-cell resolution (2020) (36)
- Role of Epiprofin, a zinc-finger transcription factor, in limb development. (2010) (36)
- β‐Catenin regulates P‐cadherin expression in mammary basal epithelial cells (2007) (33)
- Developmental Signaling in Myocardial Progenitor Cells: A Comprehensive View of Bmp- and Wnt/β-Catenin Signaling (2009) (31)
- Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence. (2015) (31)
- The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β * (2016) (30)
- Association between coated vesicles and microtubules. (1983) (30)
- The role of Irf6 in tooth epithelial invagination. (2012) (30)
- Molecular signaling mechanisms of axon–glia communication in the peripheral nervous system (2015) (30)
- Cell adhesion and signal transduction in cancer (2005) (29)
- Intracellular and extracellular components involved in the formation of ventral surfaces of fibroblasts. (1982) (28)
- Comparison of human hemoglobin A carrying glutathione as a mixed disulfide with the naturally occurring human hemoglobin A. (1973) (27)
- SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling (2019) (26)
- Summary β-Catenin regulates Cripto-and Wnt 3-dependent gene expression programs in mouse axis and mesoderm formation (26)
- The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney. (2011) (26)
- The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness (2020) (26)
- YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer (2021) (26)
- ATP-induced endocytosis in human erythrocyte ghosts. Characterization of the process and isolation of the endocytosed vesicles. (1979) (25)
- Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells (2019) (25)
- The ankyrin repeat protein Diversin recruits Casein kinase I (cid:1) to the (cid:2) -catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling (2002) (24)
- Stem cells: Orphan receptors find a home (2011) (23)
- Mesenchymal-epithelial transitions. (1994) (23)
- The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis (2014) (21)
- Fibroblast's focal contacts (1981) (21)
- The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling. (2009) (20)
- Shp2 signaling suppresses senescence in PyMT‐induced mammary gland cancer in mice (2015) (19)
- Shp2 signaling suppresses senescence in PyMT‐induced mammary gland cancer in mice (2015) (19)
- Cell adhesion and metastasis: a monoclonal antibody approach (1983) (18)
- Reaction of cytoplasmic aspartate aminotransferase with tetranitromethane. (1973) (18)
- Epithelial Morphogenesis in Development and Disease (1999) (18)
- Muscle G-actin is an inhibitor of ATP-induced erythrocyte ghost shape changes and endocytosis. (1977) (18)
- The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer. (2019) (18)
- The reactive sulfhydryl groups of cytoplasmic aspartate aminotransferase. Localization in the primary structure and spectral properties of their mixed disulfide derivatives with N-dansylcysteine. (1974) (17)
- Cell-cell adhesion in invasion and metastasis of carcinomas. (1994) (17)
- Reversion of the transformed phenotype of B16 mouse melanoma: Involvement of an 83 kd cell surface glycoprotein in specific growth inhibition (1986) (16)
- The E-cadherin promoter : Functional analysis of a GC-rich region and an epithelial cell-specific palindromic regulatory element ( epithelium-specific gene expression / initiator element / keratin promoter regulatory element / tumor differentiation / tutmor invasion ) (15)
- Attempts to understand metastasis formation. I. Metastasis-related molecules. Introduction. (1996) (15)
- Keratinocyte‐specific ablation of protease‐activated receptor 2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease (2018) (14)
- The Transcriptional Repressor Glis 2 Is a Novel Binding Partner for p 120 Catenin (2007) (12)
- beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation. (2004) (11)
- The reaction of cytoplasmic aspartate aminotransferase with bromopyruvate. Syncatalytic modification simulates affinity labeling. (1974) (11)
- Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy (2021) (10)
- High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53 (2021) (10)
- C-met activation is necessary but not sufficient for liver colonization by B16 murine melanoma cells (1998) (10)
- From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement. (2020) (10)
- Expression of E-cadherin/catenin complexes in breast cancer. (1997) (9)
- Making tubes: step by step. (2004) (9)
- Syncatalytic modification of cytoplasmic aspartate aminotransferase: Identification of a peptide containing the modified cysteinyl residue (1972) (9)
- Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain (2017) (8)
- Attempts to understand metastasis formation. II. Regulatory factors. Introduction. (1996) (7)
- The A-kinase anchoring protein ( AKAP ) glycogen synthase kinase 3 { beta } interaction protein ( GSKIP ) regulates { beta }-catenin through its interactions with both protein kinase A ( PKA ) and GSK 3 { beta } (2017) (7)
- Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury (2018) (7)
- Conference on Cadherins, Catenins and Cancer (2005) (7)
- Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice (2014) (7)
- Targeting Wnt/β-Catenin Signaling by TET1/FOXO4 Inhibits Metastatic Spreading and Self-Renewal of Cancer Stem Cells in Gastric Cancer (2022) (6)
- Metastasis-related molecules (1996) (6)
- Wnt / b-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours (2013) (6)
- The thiol groups of human hemoglobin carrying heme only on the -chains. (1972) (6)
- Syncatalytic enzyme modification: characteristic features and differentiation from affinity labeling. (1977) (6)
- Global Increase of p16INK4a in APC-Deficient Mouse Liver Drives Clonal Growth of p16INK4a-Negative Tumors (2014) (6)
- [Transforming growth factor beta and fibroblast growth factor have opposite effects on the proliferation of endothelial cells]. (1986) (5)
- Phosphorylation and dephosphorylation of spectrin from human erythrocyte ghosts under physiological conditions: autocatalysis rather than reaction with separate kinase and phosphatase. (1980) (5)
- Erratum: Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice (The EMBO Journal (2015) 34 (1493-1508) 10.15252/embj.201489004) (2015) (4)
- Molecular aspects of the loss of cell adhesion and gain of invasiveness in carcinomas. (1994) (3)
- The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis (2018) (3)
- Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency (2012) (3)
- Attempts to Understand Metastasis Formation II (1996) (3)
- in mice-catenin β disease : conditional loss-and gain-of-function mutations of Deciphering the function of canonical Wnt signals in development and (2008) (3)
- Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling (2021) (3)
- A C/EBPα–Wnt connection in gut homeostasis and carcinogenesis (2018) (3)
- YAP and β-catenin co-operate to drive oncogenesis in basal breast cancer (2020) (2)
- MLL1 is required for maintenance of intestinal stem cells (2021) (2)
- Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice (2021) (2)
- Wnt / β-catenin signaling induces MLL to create epigenetic changes in salivary gland tumors (2013) (2)
- Undercoat-constitutive proteins of cell-cell adherens junctions. (1993) (1)
- Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients (2020) (1)
- Thanks to Reviewers (2007) (1)
- myelination replaces Nrg 1 / ErbB 3 signals during Schwann cell development and Activation of MAPK overrides the termination of myelin growth and Material (2014) (1)
- Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses (2022) (1)
- Towards improved cancer diagnosis and treatment founded on current developments in the basic sciences: options for intensified European efforts. An EORTC Research Branch Scientific Advisory Board Consensus Paper. (1991) (1)
- Establishment of Kidney Cancer Organoid Cultures (2020) (1)
- E-Cadherin Expression in Primary and Metastatic Gastric Cancer: Down-Regulation Correlates with Cellular Dedifferentiation and Glandular Disintegration1 (2006) (1)
- Molecular Aspects of the Invasion of Carcinoma Cells (1992) (1)
- Cell-Cell and Cell-Substrate Contacts : Investigation by Functionally Active Monoclonal Antibodies (1985) (1)
- c-Met is essential for wound healing (2008) (1)
- Attempts to understand metastasis formation. III. Therapeutic approaches for metastasis treatment. Introduction. (1996) (1)
- Structure of cytochromec oxidase from baker's yeast—a progress report. Preparation of four subunits for amino acid sequence determination and attempts to localize the cytochromec binding site (1977) (1)
- TYROSINE KINASE RECEPTORS AS DRIVING FORCES FOR GROWTH, MOTTLTTY AND DIFFERENTIATION OF EPITHELIAL CELLS (2003) (0)
- Small-molecule inhibitors of the PDZ domain of Dishevelled 1 proteins interrupt Wnt signalling 2 3 (2021) (0)
- Regulation of neuronal differentiation by the novel neurite-outgrowth multiadaptor (NOMA) (2006) (0)
- SHP2 is a regulator of peripheral glia development and myelination (2008) (0)
- The Wnt-Driven Mll 1 Epige nome Regulates Salivary Gland and Head and Neck Cancer Graphical (2019) (0)
- E-cadherin is crucial for ESC pluripotency and can replace Oct 4 during somatic cell reprogramming (2010) (0)
- Global Increase of p 16 INK 4 a in APC-De fi cient Mouse Liver Drives Clonal Growth of p 16 INK 4 a-Negative Tumors (2014) (0)
- Negative Tumors (2017) (0)
- Supplemental Information RNF 4-Dependent Oncogene Activation by Protein Stabilization (2016) (0)
- A method for detecting the differentiation and invasiveness of carcinoma cells (1991) (0)
- Abstract P051: Function of shp-1 and shp-2 phosphatases in T cell-mediated anti-tumor response (2022) (0)
- CULTURED KERATINOCYTE GRAFTS AS PROTOTYPES FOR EPITHELIAL MORPHOGENESIS DURING WOUND HEALING (2003) (0)
- Multiple roles of mesenchymal (cid:2) -catenin during murine limb patterning (2006) (0)
- 2288Oxidized LDL/CD36/PPARg circuitry is a trigger of adipogenesis in arrhythmogenic cardiomyopathy (2019) (0)
- 3. Molecular Architecture of Oligomeric Membrane Proteins (1978) (0)
- Regulation of neurite outgrowth by the neurite-outgrowth multiadaptor RhoGAP protein, NOMA-GAP (2008) (0)
- Title Gab 1 and Mapk Signaling Are Essential in the Hair Cycle andHair Follicle Stem Cell Quiescence (2019) (0)
- Tracing tumorigenesis in a solid tumor model at single-cell resolution (2020) (0)
- RNF 4-Dependent Oncogen e Activation by Protein Stabilization Graphical Abstract Highlights (2016) (0)
- Microfilaments and Fibronectin Fibers Involved in the Formation of Fibroblast'S Focal Contacts (1982) (0)
- Regulatorische Mechanismen der Lymphozyten-Migration in der Homöostase und Immunpathologie (2007) (0)
- Shp-2 Is Dispensable for E stablishing T Cell Exhaustion and for PD-1 Signaling In Vivo Graphical (2018) (0)
- Therapeutic approaches for metastasis treatment (1996) (0)
- Regulation of cortical development by the neurite-outgrowth multiAdaptor protein, NOMA-GAP (2010) (0)
- Surface compontent at focal contacts of fibroblasts defined by a monoclonal antibody. Abstr. (1982) (0)
- Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastases (2015) (0)
- Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors (2022) (0)
- The Motility Signal of Scatter FactorlHepatocyte Growth Factor Mediated through the (1994) (0)
- Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors (2022) (0)
- Wnt/[beta]-catenin controls stem cells in regeneration and tumor formation (2010) (0)
- T-cell development occurs in the combined absence of the canonical Wnt signal-transducers beta- and gamma-catenin (2008) (0)
- Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells (2019) (0)
- Late abstracts 186–187 (2005) (0)
- MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML (2020) (0)
- Structure of cytochrome c oxidase from baker's yeast - a progress report. Preparation of four subunits for amino acid sequence determination and attempts to localize the cytochrome c binding site. (1977) (0)
- Wnt Signaling in Cancer (2016) (0)
- The co-activators of de-regulated Wnt/ß-catenin signaling, BCL9-2 and Pygo2, are potential targets for colon cancer therapy (2016) (0)
- Signaling by MET (2016) (0)
- Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain (2017) (0)
- Tumour promoting activity of TGF β (1987) (0)
- Abstract A12: YAP and cancer stem cells in basal-like breast cancer (2020) (0)
- The role of SF/HGF and E-cadherin in the formation of spontaneous metastases in nude mice (2007) (0)
- 95 POSTER Invasion knock down of human colon cancer cells by siRNA specific for S100A4, a newly identified target gene of beta-catenin/TCF signaling (2006) (0)
- Transforming Growth Factor ßas a Potent Promoter in Two-Stage BALB/c 3T3 Cell Transformation1 (2006) (0)
- Spatially Restricted Strom al Wnt Signaling Restrains Prostate Epithelial Progenitor Growth throughDirect and Indirect Mechanisms Graphical (2019) (0)
- Cover Picture: Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo (ChemMedChem 5/2015) (2015) (0)
- Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase (2018) (0)
- Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors (2023) (0)
- NOMA-GAP-dependent inhibition of Cdc 42 and activation of cofilin Neocortical dendritic complexity is controlled during development by Material Supplemental (2012) (0)
- HGF/SF c‐Met Signaling in the Epithelial–Mesenchymal Transition and Migration of Muscle Progenitor Cells (2005) (0)
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What Schools Are Affiliated With Walter Birchmeier?
Walter Birchmeier is affiliated with the following schools:
