Warren J. Strittmatter
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Why Is Warren J. Strittmatter Influential?
(Suggest an Edit or Addition)Warren J. Strittmatter's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. (1993) (8659)
- Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. (1993) (4208)
- Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease (1993) (2765)
- Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease (1994) (1772)
- Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. (1993) (1436)
- Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. (1993) (1329)
- Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. (1993) (1107)
- Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines (2002) (1008)
- A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia (2009) (462)
- Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. (1994) (458)
- Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype (1994) (454)
- Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH (1996) (453)
- Apolipoprotein E and Alzheimer disease. (1995) (452)
- Transthyretin sequesters amyloid beta protein and prevents amyloid formation. (1994) (396)
- ApoE genotype and survival from intracerebral haemorrhage (1995) (299)
- Apolipoprotein E and Alzheimer's disease. (2000) (290)
- beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling. (1979) (285)
- Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. (1997) (276)
- Apolipoprotein E Is Localized to the Cytoplasm of Human Cortical Neurons: A Light and Electron Microscopic Study (1994) (197)
- Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease (1995) (188)
- Inhibition of Polyglutamine Protein Aggregation and Cell Death by Novel Peptides Identified by Phage Display Screening* (2000) (172)
- Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes. (1979) (172)
- Apolipoprotein E Is Present in Hippocampal Neurons without Neurofibrillary Tangles in Alzheimer's Disease and in Age-Matched Controls (1994) (152)
- The role of apolipoprotein E in the nervous system. (1994) (147)
- E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. (1996) (142)
- Clinical application of apolipoprotein E genotyping to Alzheimer's disease (1994) (134)
- Rat myoblast fusion requires metalloendoprotease activity (1983) (131)
- Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila. (2003) (128)
- Impairment of the Blood–Nerve and Blood–Brain Barriers in Apolipoprotein E Knockout Mice (2001) (119)
- Benzodiazepine and β-adrenergic receptor ligands independently stimulate phospholipid methylation (1979) (113)
- Genome-wide scan of copy number variation in late-onset Alzheimer's disease. (2010) (112)
- In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease. (2003) (108)
- Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes. (1979) (105)
- Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. (1997) (100)
- Glutamate and dynorphin release from a subcellular fraction enriched in hippocampal mossy fiber synaptosomes (1988) (98)
- Polyglutamine Domains Are Substrates of Tissue Transglutaminase: Does Transglutaminase Play a Role in Expanded CAG/Poly‐Q Neurodegenerative Diseases? (1997) (97)
- Crosslinking of Apolipoprotein E by Products of Lipid Peroxidation (1996) (97)
- The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. (2000) (96)
- Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer’s disease pathology (2001) (94)
- Preliminary Report on the Association of Apolipoprotein E Polymorphisms, with Postoperative Peak Serum Creatinine Concentrations in Cardiac Surgical Patients (2000) (86)
- Requirement for metalloendoprotease in exocytosis: Evidence in mast cells and adrenal chromaffin cells (1985) (85)
- Molecular biology of apolipoprotein E (2002) (85)
- Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease (1994) (83)
- Modification of calmodulin function by enzymatic carboxyl methylation (1981) (82)
- Differential Binding of Apolipoprotein E Isoforms to Tau and Other Cytoskeletal Proteins (1996) (81)
- APOE genotype-specific differences in human and mouse macrophage nitric oxide production (2004) (79)
- Apolipoprotein E Binds to and Potentiates the Biological Activity of Ciliary Neurotrophic Factor (1997) (78)
- Pathogenesis of Inclusion Bodies in (CAG)n/Qn‐Expansion Diseases with Special Reference to the Role of Tissue Transglutaminase and to Selective Vulnerability (1999) (78)
- alpha-Adrenergic receptors in rat parotid cells. II. Desensitization of receptor binding sites and potassium release. (1977) (77)
- Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells. (1997) (65)
- Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice (2007) (62)
- [3H]Dihydroergocryptine binding in rat brain (1977) (61)
- Intraoperative Magnesium Administration Does Not Improve Neurocognitive Function After Cardiac Surgery (2013) (60)
- alpha-Adrenergic receptors in rat parotid cells. I. Correlation of [3H]dihydroergocryptine binding and catecholamine-stimulated potassium efflux. (1977) (59)
- Attenuation of the neurotoxic effect of Aβ amyloid peptide by apolipoprotein E (1994) (59)
- Interaction of Apolipoprotein E with Laminin Increases Neuronal Adhesion and Alters Neurite Morphology (1995) (59)
- Risky apolipoprotein in brain (1994) (54)
- Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm. (1987) (53)
- Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries. (2008) (53)
- Evidence for involvement of metalloendoproteases in a step in sea urchin gamete fusion (1988) (53)
- ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation (1995) (52)
- Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts. (1984) (52)
- Novel Large Apolipoprotein E‐Containing Lipoproteins of Density 1.006–1.060 g/ml in Human Cerebrospinal Fluid (1998) (51)
- Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. (2006) (48)
- Protease inhibitors implicate metalloendoprotease in synaptic transmission at the mammalian neuromuscular junction. (1983) (48)
- Expanded polyglutamine stretches form an ‘aggresome’ (2002) (47)
- Toxicity of expanded polyglutamine‐domain proteins in Escherichia coli (1996) (46)
- Apolipoprotein E E4 allele and risk of dementia. (1995) (45)
- Peripheral Sensory Nerve Defects in Apolipoprotein E Knockout Mice (1998) (42)
- Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland. (1978) (38)
- Apolipoprotein E in Creutzfeldt-Jakob disease (1995) (38)
- Old Drug, New Hope for Alzheimer's Disease (2012) (38)
- Inhibitors of metalloendoproteases block spiculogenesis in sea urchin primary mesenchyme cells. (1989) (36)
- Amino acid sequence requirements of peptides that inhibit polyglutamine-protein aggregation and cell death. (2001) (35)
- ApoE genotype-specific inhibition of apoptosiss⃞s⃞ The online version of this article (available at http://www.jlr.org) contains two supplemental figures. Published, JLR Papers in Press, May 16, 2003. DOI 10.1194/jlr.M300097-JLR200 (2003) (34)
- APOE genotype is a risk factor for neuropathy severity in diabetic patients (2003) (32)
- Glyceraldehyde 3-Phosphate Dehydrogenase Abnormality in Metabolically Stressed Huntington Disease Fibroblasts (1998) (31)
- Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms. (2001) (31)
- Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases (2013) (29)
- The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. (1995) (29)
- Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity. (2004) (28)
- APOE4-VLDL Inhibits the HDL-Activated Phosphatidylinositol 3-Kinase/Akt Pathway via the Phosphoinositol Phosphatase SHIP2 (2006) (27)
- Apolipoprotein E alleles and sensorineural hearing loss (2007) (26)
- Bathing the brain. (2013) (25)
- Avid Binding of βA Amyloid Peptide to Its Own Precursor (1993) (24)
- Expanded Polyglutamine Domain Proteins Bind Neurofilament and Alter the Neurofilament Network (1999) (23)
- Cellular functions of metallo-endoproteinases. (1991) (23)
- 18F-florbetapir Positron Emission Tomography–determined Cerebral &bgr;-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery (2018) (21)
- The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases (2011) (19)
- Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. (1981) (19)
- Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial (2019) (19)
- Disrupted Spermine Homeostasis: A Novel Mechanism in Polyglutamine-Mediated Aggregation and Cell Death (2004) (18)
- Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E. (1994) (18)
- Depression of sustained evoked potentials and glial depolarization in the spinal cord by barbiturates and by diphenylhydantoin. (1973) (18)
- Correction: A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia (2009) (17)
- An Exploratory Phase IIa Study of the PPAR delta/gamma Agonist T3D-959 Assessing Metabolic and Cognitive Function in Subjects with Mild to Moderate Alzheimer’s Disease (2019) (17)
- Low yield in the diagnostic evaluation of transient ischemic attacks (1990) (15)
- Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia (2008) (13)
- Human apolipoprotein E accelerates microtubule polymerization in vitro (1998) (13)
- Alzheimer's disease. Risky apolipoprotein in brain. (1994) (12)
- Polyglutamine Domain Proteins with Expanded Repeats Bind Neurofilament, Altering the Neurofilament Network (1999) (12)
- Phospholipid methylation: a possible mechanism of signal transduction across biomembranes. (1981) (12)
- Binding of IgG to amyloid βA4 peptide via the heavy-chain hinge region with preservation of antigen binding (1993) (11)
- Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay. (2007) (11)
- Increased amyloid , 8-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease ( phenotype / APOE 4 gene ) (2005) (11)
- Apolipoprotein E and Alzheimer’s Disease: State of the Field After Two Years (1996) (10)
- High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDLs⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of 3 figures. Published, JLR Papers in Press, January 30, 2007. (2007) (10)
- Apolipoprotein E and Alzheimer's Disease (2000) (10)
- Apolipoprotein E and brain injury: implications for children. (2005) (10)
- Avid binding of beta A amyloid peptide to its own precursor. (1993) (9)
- Sequestration of amyloid beta-peptide. (1993) (9)
- Alzheimer’s disease: the new promise. (2012) (9)
- Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly-Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions? (1998) (9)
- Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis (1984) (9)
- Studies on benzodiazepine receptors. (1980) (8)
- Apolipoprotein E: Emerging Story in the Pathogenesis of Alzheimer's Disease (1995) (8)
- Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases. (1996) (7)
- Regulation of beta-adrenergic receptors by phospholipid methylation. (1980) (6)
- Chapter 7 – Role of Proteins in the Fusion of Biological Membranes (1985) (6)
- Alzheimer's disease — reassessing the data (1992) (6)
- PROTEIN CARBOXYL‐METHYLASE MODIFIES CALMODULIN FUNCTION * (1980) (5)
- The effect of simvastatin on cerebrospinal fluid levels of apolipoprotein E in patients with alzheimer's disease (1995) (4)
- Phage display screening for peptides that inhibit polyglutamine aggregation. (2006) (4)
- ApoE genotype-specific inhibition of apoptosis (2003) (4)
- Role of Metalloendoprotease in the Fusion of Biological Membranes (1987) (3)
- PHOSPHOLIPID METHYLATION, MEMBRANE FLUIDITY AND COUPLING OF THE β-ADRENERGIC RECEPTOR (1979) (3)
- Molecular mechanisms of exocytosis: The adrenal chromaffin cell as a model system (1988) (2)
- Will neurotrophic agents be harmful in Alzheimer's disease? (1989) (2)
- ApolipoproteinE and Alzheimer's Disease (2000) (2)
- Apolipoprotein E in Creutzfeldt-Jacob disease. (1995) (2)
- The soluble metalloendoprotease required in myoblast fusion remains intracellular. (1987) (2)
- Reply to “A role for GAPDH in apoptosis and neurodegeneration” (1996) (2)
- Apolipoprotein E and Alzheimer’s Disease: Therapeutic Implications (1994) (2)
- APOE 4-VLDL Inhibits the HDL-Activated Phosphatidylinositol 3-Kinase / Akt Pathway via the Phosphoinositol Phosphatase SHIP 2 (2006) (2)
- APOLIPOPROTEIN E EPSILON 4. AUTHORS' REPLY (1994) (2)
- Apolipoprotein E-e4 and apolipoprotein E-e2 are susceptibility genes that affect the rate of disease expressivity of late-onset familial and sporadic Alzheimer disease (1994) (2)
- Specific inhibitors implicate a soluble metalloendoproteinase in exocytosis (1987) (2)
- Neuropathological and neuropsychological changes in Alzheimer's disease. Relationship of biologic markers to behavioral markers. (1989) (1)
- The PIONEER Study: A multi‐center, randomized, double‐blind, placebo‐controlled phase 2 trial of the effects of T3D‐959 on safety, cognition, function and plasma biomarkers in mild to moderate Alzheimer’s disease subjects: Rationale and study design (2020) (1)
- Apolipoprotein E (APOE) Genotype as a Determinant of Survival in Women with Chronic Lymphocytic Leukemia. (2007) (1)
- Interactions of Apolipoprotein E with Microtubule-Associated Proteins (1996) (1)
- Integrative functions of the autonomic nervous system. edited by Chandler McC. Brooks, Kiyomi Koizumi, and Akio Sato. Elsevierlnorth‐holland biomedical press, amsterdam, 1979 508 pp, illustrated, $85.25 (1981) (1)
- Re: Apolipoprotein E ε4 (1994) (0)
- Methods to detect Alzheimer's disease. (1993) (0)
- The PIONEER Study: A Multi‐center, Randomized, Double‐blind, Placebo‐controlled Phase 2 Trial of the Effects of T3D‐959 on Safety, Cognition, Function and Plasma Biomarkers in Mild to Moderate Alzheimer’s Disease Subjects: Study Update. (2022) (0)
- Verwendunf of ApoE for binding TAU and MAP2c proteins and for the treatment of Alzheimer's disease (1994) (0)
- 217. Apolipoprotein is a susceptibility genetic locus that affects the expression of late-onset familial and sporadic Alzheimer's disease (1996) (0)
- Apolipoprotein E ε4 (1994) (0)
- The 18 th Annual Meeting of the European (2017) (0)
- Towards a more representative Alzheimer’s disease clinical trial: Ethnic differences in underlying pathology call for demographic consideration in drug label development (2022) (0)
- Vascular abnormalities in APOE4,4 and APOE3,3 Alzheimer's disease (2000) (0)
- EFFECTS OF A PPAR DELTA/GAMMA AGONIST, T3D-959, ON METABOLIC AND COGNITIVE FUNCTIONS IN MILD TO MODERATE ALZHEIMER’S DISEASE SUBJECTS (2018) (0)
- Apoliporotein E is a susceptibility locus for Alzheimer disease (1995) (0)
- Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases (2013) (0)
- Who Progresses from Mild Cognitive Impairment to Alzheimer Disease (2007) (0)
- Is APOE a Risk Factor for Cerebrovascular Injury (2006) (0)
- Interrelationships of Energy Metabolism to Oxidative Damage and Neurodegeneration (1998) (0)
- Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease (2011) (0)
- f 3-Adrenergic receptor agonists increase phospholipid methylation , membrane fluidity , and fl-adrenergic receptor-adenylate cyclase coupling ( membrane translocation / fluidity / S-adenosylmethionine / reticulocytes ) (0)
- Traitement de maladies neurodegeneratives (2006) (0)
- ORIGINAL ARTICLE Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia (2008) (0)
- Aging Chromosomes, Alzheimer Disease, and APOE (2006) (0)
- Isoform-Specific Metabolism of Apolipoprotein E: Implications for Alzheimer ’s Disease (1997) (0)
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