Wendy Barclay
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British virologist
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Biology
Why Is Wendy Barclay Influential?
(Suggest an Edit or Addition)According to Wikipedia, Wendy Sue Fox is a British virologist. She is currently head of Department of Infectious Disease and chair in Influenza Virology at Imperial College London. She leads a team of scientists studying the influenza virus and its physiology and morphology to discover novel vaccines. In particular, they are trying to understand more about influenza virus mutations, and how they can allow scientists to create new vaccines against possible flu pandemics.
Wendy Barclay's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion (2021) (737)
- Cellular immune correlates of protection against symptomatic pandemic influenza (2013) (718)
- RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection (2010) (541)
- Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection (2013) (504)
- Mapping the human genetic architecture of COVID-19 (2021) (455)
- Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study (2021) (444)
- The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets (2021) (411)
- A Complicated Message: Identification of a Novel PB1-Related Protein Translated from Influenza A Virus Segment 2 mRNA (2009) (397)
- Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study (2020) (384)
- The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection (2020) (319)
- Host and viral determinants of influenza A virus species specificity (2018) (285)
- Identification of a cis-Acting Replication Element within the Poliovirus Coding Region (2000) (275)
- Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice (2020) (268)
- Infection of Human Airway Epithelium by Human and Avian Strains of Influenza A Virus (2006) (260)
- Effect of previous SARS-CoV-2 infection on humoral and T-cell responses to single-dose BNT162b2 vaccine (2021) (252)
- The origins of SARS-CoV-2: A critical review (2021) (235)
- The mechanism of resistance to favipiravir in influenza (2018) (219)
- Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia (2021) (210)
- Functional Analysis of Cell Surface-Expressed Hepatitis C Virus E2 Glycoprotein (1999) (203)
- Species difference in ANP32A underlies influenza A virus polymerase host restriction (2015) (187)
- The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry (2022) (179)
- The M1 matrix protein controls the filamentous phenotype of influenza A virus. (2004) (176)
- A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria. (2004) (172)
- Antibody prevalence for SARS-CoV-2 in England following first peak of the pandemic: REACT2 study in 100,000 adults (2020) (168)
- The 5'-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translation (1994) (162)
- Investigating SARS-CoV-2 surface and air contamination in an acute healthcare setting during the peak of the COVID-19 pandemic in London (2020) (155)
- A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine. (2009) (150)
- SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic (2021) (139)
- Viral determinants of influenza A virus host range. (2014) (137)
- Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study (2021) (136)
- Declining prevalence of antibody positivity to SARS-CoV-2: a community study of 365,000 adults (2020) (135)
- Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination (2021) (134)
- Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults (2022) (120)
- Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway. (2006) (112)
- Investigating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Surface and Air Contamination in an Acute Healthcare Setting During the Peak of the Coronavirus Disease 2019 (COVID-19) Pandemic in London (2020) (110)
- SARS-CoV-2 one year on: evidence for ongoing viral adaptation (2021) (107)
- Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey (2020) (105)
- Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase (2010) (101)
- Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study (2021) (98)
- Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection (2021) (98)
- Expression of a foreign protein by influenza A virus (1994) (95)
- NS1 Proteins of Avian Influenza A Viruses Can Act as Antagonists of the Human Alpha/Beta Interferon Response (2006) (95)
- Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK (2021) (94)
- Structure of an avian influenza A virus NS1 protein effector domain. (2008) (91)
- Increased transmission of SARS-CoV-2 lineage B.1.1.7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape (2021) (88)
- Avian Influenza Virus Glycoproteins Restrict Virus Replication and Spread through Human Airway Epithelium at Temperatures of the Proximal Airways (2009) (86)
- HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation (2009) (86)
- The SARS-CoV-2 variants associated with infections in India, B.1.617, show enhanced spike cleavage by furin (2021) (83)
- Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant (2021) (82)
- Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom (2014) (81)
- The time course of the humoral immune response to rhinovirus infection (1989) (80)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol. (2020) (79)
- The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells (2020) (79)
- Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study (2021) (77)
- Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor (2014) (76)
- Resurgence of SARS-CoV-2: Detection by community viral surveillance (2021) (76)
- Viral factors in influenza pandemic risk assessment (2016) (76)
- Glycomic Characterization of Respiratory Tract Tissues of Ferrets (2014) (76)
- Rapid increase in Omicron infections in England during December 2021: REACT-1 study (2021) (75)
- Mutations in H5N1 Influenza Virus Hemagglutinin that Confer Binding to Human Tracheal Airway Epithelium (2009) (75)
- Knowns and unknowns of influenza B viruses. (2016) (75)
- Restrictions to the Adaptation of Influenza A Virus H5 Hemagglutinin to the Human Host (2004) (74)
- Characterization of recombinant influenza B viruses with key neuraminidase inhibitor resistance mutations. (2005) (74)
- Assessing a novel, lab-free, point-of-care test for SARS-CoV-2 (CovidNudge): a diagnostic accuracy study (2020) (73)
- Obesity and susceptibility to severe outcomes following respiratory viral infection (2013) (72)
- The Short Stalk Length of Highly Pathogenic Avian Influenza H5N1 Virus Neuraminidase Limits Transmission of Pandemic H1N1 Virus in Ferrets (2013) (72)
- Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus (1994) (70)
- A poliovirus replicon containing the chloramphenicol acetyltransferase gene can be used to study the replication and encapsidation of poliovirus RNA (1992) (70)
- Molecular studies of influenza B virus in the reverse genetics era. (2011) (68)
- Handheld Point-of-Care System for Rapid Detection of SARS-CoV-2 Extracted RNA in under 20 min (2021) (67)
- SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19 (2021) (66)
- SARS-CoV-2 B.1.617.2 Delta variant replication, sensitivity to neutralising antibodies and vaccine breakthrough (2021) (65)
- Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness (2010) (65)
- A Reverse Genetics Approach for Recovery of Recombinant Influenza B Viruses Entirely from cDNA (2002) (65)
- Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility (2013) (63)
- Population antibody responses following COVID-19 vaccination in 212,102 individuals (2022) (61)
- Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry. (2015) (60)
- Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020 (2020) (60)
- Prevalence of antibody positivity to SARS-CoV-2 following the first peak of infection in England: Serial cross-sectional studies of 365,000 adults (2021) (60)
- Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase (2011) (60)
- Community prevalence of SARS-CoV-2 virus in England during May 2020: REACT study (2020) (56)
- Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK (2021) (56)
- Changes in in vitro susceptibility of influenza A H3N2 viruses to a neuraminidase inhibitor drug during evolution in the human host. (2004) (55)
- The Effect of the PB2 Mutation 627K on Highly Pathogenic H5N1 Avian Influenza Virus Is Dependent on the Virus Lineage (2013) (54)
- Alterations in Receptor Binding Properties of Recent Human Influenza H3N2 Viruses Are Associated with Reduced Natural Killer Cell Lysis of Infected Cells (2007) (53)
- Receptor Binding Profiles of Avian Influenza Virus Hemagglutinin Subtypes on Human Cells as a Predictor of Pandemic Potential (2010) (51)
- Adjuvant-Free Immunization with Hemagglutinin-Fc Fusion Proteins as an Approach to Influenza Vaccines (2010) (51)
- The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein (2022) (51)
- Species specific differences in use of ANP32 proteins by influenza A virus (2019) (51)
- Host ANP32A mediates the assembly of the influenza virus replicase (2020) (50)
- COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study (2021) (49)
- Investigation of Influenza Virus Polymerase Activity in Pig Cells (2012) (48)
- Lack of transmission of a human influenza virus with avian receptor specificity between ferrets is not due to decreased virus shedding but rather a lower infectivity in vivo. (2011) (48)
- Antigenic mapping of an H9N2 avian influenza virus reveals two discrete antigenic sites and a novel mechanism of immune escape (2016) (47)
- Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry (2015) (47)
- Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines (2001) (47)
- Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England (2022) (47)
- Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments (2018) (47)
- Encapsidation studies of poliovirus subgenomic replicons. (1998) (45)
- Influenza B viruses with site-specific mutations introduced into the HA gene (1995) (44)
- ANP32 Proteins Are Essential for Influenza Virus Replication in Human Cells (2019) (44)
- Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance (2016) (44)
- Low Dose Influenza Virus Challenge in the Ferret Leads to Increased Virus Shedding and Greater Sensitivity to Oseltamivir (2014) (44)
- Transmission of a 2009 H1N1 Pandemic Influenza Virus Occurs before Fever Is Detected, in the Ferret Model (2012) (43)
- REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (2021) (43)
- Unstable Polymerase-Nucleoprotein Interaction Is Not Responsible for Avian Influenza Virus Polymerase Restriction in Human Cells (2012) (43)
- Determining the Mutation Bias of Favipiravir in Influenza Virus Using Next-Generation Sequencing (2018) (43)
- SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study (2021) (42)
- The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells (2021) (42)
- Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study (2021) (42)
- Pause on avian flu transmission research. (2012) (41)
- Urgent challenges in implementing live attenuated influenza vaccine. (2018) (41)
- Exponential growth, high prevalence of SARS-CoV-2 and vaccine effectiveness associated with Delta variant in England during May to July 2021 (2021) (40)
- Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion (2017) (40)
- REACT-2 Round 5: increasing prevalence of SARS-CoV-2 antibodies demonstrate impact of the second wave and of vaccine roll-out in England (2021) (40)
- Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge (2022) (40)
- The N-Terminal Extension of the Influenza B Virus Nucleoprotein Is Not Required for Nuclear Accumulation or the Expression and Replication of a Model RNA (1998) (39)
- The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK (2022) (39)
- The evolutionary dynamics of influenza A virus adaptation to mammalian hosts (2013) (39)
- Antiviral Screening of Multiple Compounds against Ebola Virus (2016) (39)
- Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy (2018) (38)
- M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza (2017) (38)
- Transmission Studies Resume for Avian Flu (2013) (37)
- Predominance of heterosubtypic IFN‐γ‐only‐secreting effector memory T cells in pandemic H1N1 naive adults (2012) (36)
- Fatal Cases of Influenza A in Childhood (2009) (34)
- Computational and molecular analysis of conserved influenza A virus RNA secondary structures involved in infectious virion production (2016) (33)
- Usability and acceptability of home-based self-testing for SARS-CoV-2 antibodies for population surveillance. (2020) (33)
- Suitability of PER.C6 cells to generate epidemic and pandemic influenza vaccine strains by reverse genetics. (2009) (33)
- Immunogenicity and antigenicity of chimeric picornaviruses which express hepatitis A virus (HAV) peptide sequences: evidence for a neutralization domain near the amino terminus of VP1 of HAV. (1992) (33)
- Generation of candidate human influenza vaccine strains in cell culture – rehearsing the European response to an H7N1 pandemic threat (2007) (33)
- Pause on Avian Flu Transmission Research (2012) (32)
- Influenza A virus PB1-F2 protein prolongs viral shedding in chickens lengthening the transmission window (2016) (32)
- Phosphorylation of the M2 protein of influenza A virus is not essential for virus viability. (1998) (31)
- Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics (2017) (29)
- A Single Amino Acid in the HA of pH1N1 2009 Influenza Virus Affects Cell Tropism in Human Airway Epithelium, but Not Transmission in Ferrets (2011) (29)
- Preparing for a challenging winter 2020/21 (2020) (28)
- Entry of the bat influenza H17N10 virus into mammalian cells is enabled by the MHC class II HLA-DR receptor (2019) (28)
- Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study (2019) (26)
- Immune Responses in Pigs Vaccinated with Adjuvanted and Non-Adjuvanted A(H1N1)pdm/09 Influenza Vaccines Used in Human Immunization Programmes (2012) (26)
- Host Determinants of Influenza RNA Synthesis. (2019) (26)
- Usability and Acceptability of Home-based Self-testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies for Population Surveillance (2020) (26)
- Context-specific emergence and growth of the SARS-CoV-2 Delta variant (2021) (26)
- Resistance of endothelial cells to SARS-CoV-2 infection in vitro (2020) (25)
- Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice (2018) (25)
- An influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo (2012) (25)
- High prevalence of SARS-CoV-2 swab positivity and increasing R number in England during October 2020: REACT-1 round 6 interim report (2020) (24)
- Influenza Pandemics (1961) (24)
- REACT-1 round 7 updated report: regional heterogeneity in changes in prevalence of SARS-CoV-2 infection during the second national COVID-19 lockdown in England (2020) (24)
- Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission (2020) (23)
- SARS-CoV-2 variant biology: immune escape, transmission and fitness (2023) (23)
- Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway (2022) (23)
- An ELISA for the detection of rhinovirus specific antibody in serum and nasal secretion (1987) (22)
- Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A (2019) (22)
- One‐way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential (2015) (22)
- The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies (2021) (21)
- Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2018) (21)
- A common TMPRSS2 variant has a protective effect against severe COVID-19 (2022) (21)
- Development of a Reverse Genetics System Enabling theRescue of Recombinant Avian Influenza Virus A/Turkey/England/50-92/91 (H5N1) (2007) (20)
- Pandemic risks from bird flu (2004) (20)
- Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity (2020) (20)
- RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals (2019) (20)
- The Development of a Reverse Genetics System Enabling the Rescue of Recombinant Avian Influenza Virus, A/turkey/england/50-92/91 (H5N1) (2007) (19)
- Influenza Virus with Increased pH of Hemagglutinin Activation Has Improved Replication in Cell Culture but at the Cost of Infectivity in Human Airway Epithelium (2019) (19)
- An early warning system for emerging SARS-CoV-2 variants (2022) (19)
- Resurgence of SARS-CoV-2 in England: detection by community antigen surveillance (2020) (19)
- Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease (2013) (19)
- SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): a series of cross-sectional random community surveys (2022) (18)
- Swine ANP32A Supports Avian Influenza Virus Polymerase (2020) (18)
- M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. (2017) (18)
- The value of open-source clinical science in pandemic response: lessons from ISARIC (2021) (17)
- Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England (2022) (17)
- Regulation of influenza a virus mRNA splicing by CLK1. (2019) (17)
- Assays to Measure the Activity of Influenza Virus Polymerase. (2018) (17)
- A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future. (2021) (17)
- SARS-CoV-2 environmental contamination from hospitalised patients with COVID-19 receiving aerosol-generating procedures (2021) (17)
- Evaluation of an enzyme‐linked immunosorbent assay that measures rhinovirus‐specific antibodies in human sera and nasal secretions (1988) (16)
- Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort study (2022) (16)
- REACT-1 round 6 updated report: high prevalence of SARS-CoV-2 swab positivity with reduced rate of growth in England at the start of November 2020 (2020) (16)
- Variant-specific symptoms of COVID-19 among 1,542,510 people in England (2022) (15)
- Probing the receptor interactions of an H5 avian influenza virus using a baculovirus expression system and functionalised poly(acrylic acid) ligands. (2007) (15)
- Reduced incorporation of the influenza B virus BM2 protein in virus particles decreases infectivity. (2004) (15)
- Author Correction: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (2019) (15)
- Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2 (2022) (15)
- Neutralising antibody activity against SARS-CoV-2 variants, including Omicron, in an elderly cohort vaccinated with BNT162b2 (2021) (14)
- Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model (2020) (14)
- Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England (2021) (14)
- Favipiravir-resistant influenza A virus shows potential for transmission (2020) (14)
- Community Transmission and Viral Load Kinetics of SARS-CoV-2 Delta (B.1.617.2)Variant in Vaccinated and Unvaccinated Individuals (2021) (14)
- Affinity purified immunoglobulin G transfers immediate hypersensitivity to guinea pig colonic epithelium in vitro. (1987) (14)
- High prevalence of SARS-CoV-2 swab positivity in England during September 2020: interim report of round 5 of REACT-1 study (2020) (14)
- Post-peak dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 (2022) (13)
- Introduction of foreign sequences into the genome of influenza A virus. (1994) (13)
- REACT-1 study round 14: High and increasing prevalence of SARS-CoV-2 infection among school-aged children during September 2021 and vaccine effectiveness against infection in England (2021) (13)
- NB protein does not affect influenza B virus replication in vitro and is not required for replication in or transmission between ferrets. (2016) (13)
- REACT-1 round 8 final report: high average prevalence with regional heterogeneity of trends in SARS-CoV-2 infection in the community in England during January 2021 (2021) (13)
- Transient dynamics of SARS-CoV-2 as England exited national lockdown (2020) (12)
- Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England (2022) (12)
- A handheld point-of-care system for rapid detection of SARS-CoV-2 in under 20 minutes (2020) (12)
- Inactivation of SARS-CoV-2 in chlorinated swimming pool water (2021) (12)
- Context-specific emergence and growth of the SARS-CoV-2 Delta variant (2022) (12)
- Amino acid substitution D222N from fatal influenza infection affects receptor-binding properties of the influenza A(H1N1)pdm09 virus. (2015) (12)
- Ultrastructure of cell trafficking pathways and coronavirus: how to recognise the wolf amongst the sheep (2020) (12)
- REACT-1 round 9 final report: Continued but slowing decline of prevalence of SARS-CoV-2 during national lockdown in England in February 2021 (2021) (12)
- The cellular localization of avian influenza virus PB1-F2 protein alters the magnitude of IFN2 promoter and NFκB-dependent promoter antagonism in chicken cells. (2019) (12)
- High and increasing prevalence of SARS-CoV-2 swab positivity in England during end September beginning October 2020: REACT-1 round 5 updated report (2020) (12)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol (2021) (11)
- REACT-1 round 7 interim report: fall in prevalence of swab-positivity in England during national lockdown (2020) (11)
- REACT-1 round 13 interim report: acceleration of SARS-CoV-2 Delta epidemic in the community in England during late June and early July 2021 (2021) (11)
- Vaccine uptake and SARS-CoV-2 antibody prevalence among 207,337 adults during May 2021 in England: REACT-2 study (2021) (11)
- SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2 (2021) (11)
- Rapid generation of a well-matched vaccine seed from a modern influenza A virus primary isolate without recourse to eggs. (2010) (11)
- REACT-1 round 9 interim report: downward trend of SARS-CoV-2 in England inFebruary 2021 but still at high prevalence (2021) (10)
- Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study (2022) (10)
- REACT-1 round 8 interim report: SARS-CoV-2 prevalence during the initial stages of the third national lockdown in England (2021) (10)
- Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5 (2022) (10)
- The 1918 Influenza Pandemic: one hundred years of progress, but where now? (2018) (10)
- Appropriately smoothing prevalence data to inform estimates of growth rate and reproduction number (2022) (10)
- SARS-CoV-2 lineage dynamics in England from January to March 2021 inferred from representative community samples (2021) (9)
- Dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 in England (2022) (9)
- Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium (2022) (9)
- An engineered avian-origin influenza A virus for pancreatic ductal adenocarcinoma virotherapy. (2016) (9)
- Host Cell Factors That Interact with Influenza Virus Ribonucleoproteins. (2020) (9)
- The Functional Study of the N-Terminal Region of Influenza B Virus Nucleoprotein (2015) (9)
- Molecular characterization of Iranian wheat stripe virus shows its taxonomic position as a distinct species in the genus Tenuivirus (2006) (9)
- Population implications of the deployment of novel universal vaccines against epidemic and pandemic influenza (2020) (8)
- REACT-1 round 15 final report: Increased breakthrough SARS-CoV-2 infections among adults who had received two doses of vaccine, but booster doses and first doses in children are providing important protection (2021) (8)
- SARS-CoV-2 variants of concern Alpha, Beta, Gamma and Delta have extended ACE2 receptor host-ranges (2021) (8)
- Unravelling the mysteries of influenza (2002) (8)
- Characterising the persistence of RT-PCR positivity and incidence in a community survey of SARS-CoV-2 (2021) (7)
- Passage of influenza A/H3N2 viruses in human airway cells removes artefactual variants associated with neuraminidase-mediated binding (2019) (7)
- Naïve Human Macrophages Are Refractory to SARS-CoV-2 Infection and Exhibit a Modest Inflammatory Response Early in Infection (2022) (7)
- The Omicron SARS-CoV-2 epidemic in England during February 2022 (2022) (7)
- The Emergence of H7N7 Highly Pathogenic Avian Influenza Virus from Low Pathogenicity Avian Influenza Virus Using an in ovo Embryo Culture Model (2020) (7)
- Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study (2022) (7)
- Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway (2021) (7)
- Transmission of SARS-CoV-2 by children attending school. Interim report on an observational, longitudinal sampling study of infected children, contacts, and the environment (2021) (6)
- Transmission of SARS-CoV-2 by children to contacts in schools and households: a prospective cohort and environmental sampling study in London (2022) (6)
- Ferret airway epithelial cell cultures support efficient replication of influenza B virus but not mumps virus. (2015) (6)
- Receptor for bat influenza virus uncovers potential risk to humans (2019) (6)
- Publisher Correction: Host and viral determinants of influenza A virus species specificity (2018) (6)
- Influenza: a world of discoveries, outbreaks and controversy. (2017) (6)
- Increasing SARS-CoV-2 antibody prevalence in England at the start of the second wave: REACT-2 Round 4 cross-sectional study in 160,000 adults (2021) (6)
- Acceptability, Usability, and Performance of Lateral Flow Immunoassay Tests for Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies: REACT-2 Study of Self-Testing in Nonhealthcare Key Workers (2021) (6)
- A natural variant in ANP32B impairs influenza virus replication in human cells (2021) (6)
- Breakthrough SARS-CoV-2 infections in double and triple vaccinated adults and single dose vaccine effectiveness among children in Autumn 2021 in England: REACT-1 study (2022) (6)
- The new normal? Dynamics and scale of the SARS-CoV-2 variant Omicron epidemic in England (2022) (5)
- Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza (2019) (5)
- The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome (2022) (5)
- Multisystem screening reveals SARS‐CoV‐2 in neurons of the myenteric plexus and in megakaryocytes (2022) (5)
- 2020 Hindsight: Should evolutionary virologists have expected the unexpected during a pandemic? (2021) (5)
- SARS-CoV-2 variants of concern alpha, beta, gamma and delta have extended ACE2 receptor host ranges. (2022) (5)
- Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19 (2022) (5)
- REACT-1 round 10 report: Level prevalence of SARS-CoV-2 swab-positivity in England during third national lockdown in March 2021 (2021) (5)
- Isolation and characterization of a transfectant influenza B virus altered in RNA segment 6. (1999) (5)
- Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing (2018) (5)
- Pregnancy-related immune suppression leads to altered influenza vaccine recall responses. (2019) (4)
- REACT-1 round 11 report: low prevalence of SARS-CoV-2 infection in the community prior to the third step of the English roadmap out of lockdown (2021) (4)
- Delta variant emergence , replication and sensitivity to 1 neutralising antibodies 2 3 (2021) (4)
- Quantifying mechanistic traits of influenza viral dynamics using in vitro data. (2020) (4)
- Omicron breakthrough infections in vaccinated or previously infected hamsters (2022) (4)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol [version 1;peer review: awaiting peer review] (2020) (4)
- Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys (2022) (4)
- Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1 (2022) (4)
- CovidNudge: diagnostic accuracy of a novel lab-free point-of-care diagnostic for SARS-CoV-2 (2020) (4)
- Robustness of the Ferret Model for Influenza Risk Assessment Studies: a Cross-Laboratory Exercise (2022) (3)
- Using Reverse Genetics to Improve Influenza Vaccines (2012) (3)
- Is there evidence for genetic change in SARS-CoV-2 and if so, do mutations affect virus phenotype? (3)
- Enzalutamide, a prostate cancer therapeutic, downregulates TMPRSS2 in lung and reduces cellular entry of SARS-CoV-2 (2021) (3)
- ACE2: The Only Thing That Matters? (2020) (3)
- SARS-CoV-2 environmental contamination from hospitalised COVID-19 patients receiving aerosol generating procedures (2021) (3)
- Trends in SARS-CoV-2 infection prevalence during England’s roadmap out of lockdown, January to July 2021 (2022) (3)
- Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study (3)
- Ultrastructural insight into SARS-CoV-2 attachment, entry and budding in human airway epithelium (2021) (3)
- Can defective interfering RNAs affect the live attenuated influenza vaccine? - Authors' reply. (2017) (3)
- Mammalian ANP32A and ANP32B proteins drive alternative avian influenza virus polymerase adaptations (2020) (3)
- Host and viral determinants of influenza A virus species specificity (2018) (2)
- REACT-1 round 15 interim report: High and rising prevalence of SARS-CoV-2 infection in England from end of September 2021 followed by a fall in late October 2021 (2021) (2)
- SARS-CoV-2 Antibody Lateral Flow Assay for antibody prevalence studies following vaccine roll out: a Diagnostic Accuracy Study (2021) (2)
- Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection (2021) (2)
- Acceptability, usability and performance of lateral flow immunoassay tests for SARS-CoV-2 antibodies: REACT-2 study of self-testing in non-healthcare key workers (2021) (2)
- Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis (2022) (2)
- A rare variant in ANP32B impairs influenza virus replication in human cells (2020) (2)
- A self-amplifying RNA vaccine protects against SARS-CoV-2 (D614G) and Alpha variant of concern (B.1.1.7) in a transmission-challenge hamster model (2022) (2)
- Cellular reproduction number, generation time and growth rate differ between human- and avian-adapted influenza strains (2019) (2)
- Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice (2020) (2)
- Aberrant RNA replication products of highly pathogenic avian influenza viruses and its impact in the mammalian associated cytokine storm (2019) (2)
- The impact of an updated pandemic H1N1 strain on shedding and immunogenicity to Russian-backbone live attenuated influenza vaccine among children in The Gambia: an open-label, observational, phase 4 study (2019) (2)
- Context-specific emergence and growth of the SARS-CoV-2 Delta variant (2021) (1)
- Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study (2023) (1)
- Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature upon SARS-CoV-2 sensing by monocytes in COVID-19 (2022) (1)
- Amino acid substitutions in the H5N1 avian influenza haemagglutinin alter pH of fusion and receptor binding to promote a highly pathogenic phenotype in chickens (2021) (1)
- A new combination testing methodology to identify accurate and economical point-of-care testing strategies (2021) (1)
- Publisher Correction: Host and viral determinants of influenza A virus species specificity (2018) (1)
- Viral Emissions into the Air and Environment after SARS-CoV-2 Human Challenge: A Phase 1, Open Label, First-in-Human Study (2022) (1)
- Considerations in the deployment of novel universal vaccines against epidemic and pandemic influenza (2019) (1)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody lateral flow assay for antibody prevalence studies following vaccination: a diagnostic accuracy study. (2021) (1)
- Overexpression of α-2,6-Sialyltransferase in PER.C6® cells leads to increased susceptibility for human influenza strains Submitted for publication (2010) (1)
- Symptom‐based case definitions for COVID‐19: Time and geographical variations for detection at hospital admission among 260,000 patients (2022) (1)
- How long will vaccines continue to protect against COVID ? (2021) (1)
- Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study (2022) (1)
- Avian ANP32B does not support influenza A virus polymerase and influenza A virus relies exclusively on ANP32A in chicken cells (2019) (1)
- Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model (2022) (1)
- Quantifying changes in the IFR and IHR over 23 months of the SARS-CoV-2 pandemic in England (2022) (1)
- Viral Infectivity in Patients Undergoing Tracheotomy With COVID-19: A Preliminary Study (2021) (1)
- Validity of Self-testing at Home With Rapid Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Detection by Lateral Flow Immunoassay (2022) (1)
- Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo (2022) (1)
- Polymer formulated self-amplifying RNA vaccine is partially protective against influenza virus infection in ferrets (2022) (1)
- Amino acid substitution D 222 N from fatal in fl uenza infection affects receptor-binding properties of the in fl uenza A ( H 1 N 1 ) pdm 09 virus (2015) (1)
- Design and Implementation of a National SARS-CoV-2 Monitoring Program in England: REACT-1 Study. (2023) (1)
- REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol [version 1; peer review: 1 approved, 1 approved with reservations] (2021) (1)
- Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway. (2021) (1)
- Rapid emergence of transmissible SARS-CoV-2 variants in mild community cases (2023) (0)
- Supplementary material from "Population implications of the deployment of novel universal vaccines against epidemic and pandemic influenza" (2020) (0)
- Propylene glycol inactivates respiratory viruses and prevents airborne transmission (2023) (0)
- Treatment of irritant contact dermatitis in healthcare settings during the COVID19 pandemic: The emollient Dermol 500 exhibits virucidal activity against influenza A virus and SARS-CoV-2. (2021) (0)
- acute healthcare 1 setting during the peak of the COVID-19 pandemic in London 2 3 Running Title : SARS-CoV-2 air and surface contamination (2020) (0)
- Population antibody responses following COVID-19 vaccination in 212,102 individuals (2022) (0)
- The use of representative community samples to assess SARS-CoV-2 lineage competition: Alpha outcompetes Beta and wild-type in England from January to March 2021 (2023) (0)
- The SARS-CoV-2 variants associated with 1 infections in India, B.1.617, show 2 enhanced spike cleavage by furin 3 (2021) (0)
- Host ANP32A mediates the assembly of the influenza virus replicase (2020) (0)
- SARS-CoV-2 B.1.617.2 Delta variant replication, sensitivity to neutralising antibodies 1 and vaccine breakthrough 2 (2021) (0)
- Behavioural responses to SARS-CoV-2 antibody testing in England: REACT-2 study (2021) (0)
- Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people: a large community cross-sectional study in England (2023) (0)
- UvA-DARE ( Digital Academic Repository ) New technologies for the control of influenza Koudstaal (2010) (0)
- Computational molecular of conserved virus RNA (2016) (0)
- Activity in Pig Cells Investigation of Influenza Virus Polymerase (2014) (0)
- Attenuating mutations in the influenza virus genome which may increase the safety of vaccine production (2004) (0)
- Primary macrophages exhibit a modest inflammatory response early in SARS-CoV-2 infection (2022) (0)
- Receptor for bat influenza virus uncovers potential risk to humans (2019) (0)
- The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis (2023) (0)
- In vitro expression studies of three proteins of Iranian wheat stripe virus (2008) (0)
- The MHC class-II HLA-DR receptor mediates bat influenza A-like H17N10 virus entry into mammalian cells (2019) (0)
- Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types (2023) (0)
- Evaluation of the impact of pre-analytical conditions on sample stability for the detection of SARS-CoV-2 RNA (2022) (0)
- The Consequences of Egg Adaptation in the H3N2 Component to the Immunogenicity of Live Attenuated Influenza Vaccine (2019) (0)
- SARS-CoV-2 surface and air contamination in an acute healthcare setting during the first and second pandemic waves (2022) (0)
- ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19 (2022) (0)
- Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential (2023) (0)
- P251 The induction of early, dynamic airway mucosal and systemic immune responses following recent SARS-CoV-2 household exposure (2021) (0)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody lateral flow assay for antibody prevalence studies following vaccination: a diagnostic accuracy study (2022) (0)
- Studying the mammalian adaptation potential of influenza A viruses in a single infection cycle (2019) (0)
- Update on Immunity to SARS CoV2 (0)
- Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus (2023) (0)
- Modelling Of Influenza A-Induced Acute Lung Injury (ALI) And Repair: The Development Of Novel Ex Vivo And In Vitro Models (2012) (0)
- in the United Kingdom A(H1N1)pdm09 Influenza Virus in Humans Mutations during Circulation of Accumulation of Human-Adapting (2014) (0)
- This is a repository copy of Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children (2019) (0)
- Tropism and neutralisation studies on bat influenza H17N10 (2020) (0)
- Influenza virus lethal assortants (2014) (0)
- Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines (2001) (0)
- Visualising influenza virus replication using a click chemistry approach (2019) (0)
- Binding of SARS-CoV-2 to the avb6 Integrins May Promote Severe COVID in Patients with IPF (2021) (0)
- The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection (2023) (0)
- Type I interferon signaling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice (2022) (0)
- Correction to: The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK (2022) (0)
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