Wendy Havran
American immunologist
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Biology
Wendy Havran's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Immunology Stanford University
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(Suggest an Edit or Addition)According to Wikipedia, Wendy Havran was an American immunologist at the Scripps Research Institute. She specialized in T cells, showing that they are scarce in certain areas of the body. Life Havran was born in Houston, Texas, and would visit science museums and natural parks with her family. She attended Duke University, where she learned about immunology and received a bachelor's degree in zoology. Havran attended the University of Chicago and worked in the laboratory of Dr.Frank Fitch for her doctorate degrees. Havran completed her post-doctoral training with Dr. James P. Allison at the University of California. This is where she earned the Lucille P. Markey Scholar in Biomedical grant.
Wendy Havran's Published Works
Published Works
- Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity (1983) (1028)
- Modulation of epithelial cell growth by intraepithelial gamma delta T cells. (1994) (631)
- A Role for Skin γδ T Cells in Wound Repair (2002) (567)
- Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors (1988) (543)
- Protection of the intestinal mucosa by intraepithelial γδ T cells (2002) (443)
- Recognition of self antigens by skin-derived T cells with invariant gamma delta antigen receptors. (1991) (346)
- The immunobiology of T cells with invariant γδ antigen receptors (1991) (323)
- Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors (1990) (318)
- γδ T cells in homeostasis and host defence of epithelial barrier tissues (2017) (303)
- A role for human skin–resident T cells in wound healing (2007) (281)
- Epithelial decision makers: in search of the 'epimmunome' (2010) (278)
- Chemokine expression by intraepithelial gamma delta T cells. Implications for the recruitment of inflammatory cells to damaged epithelia. (1996) (256)
- Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1 (2005) (232)
- Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes (1987) (230)
- Epidermal T Cells and Wound Healing (2010) (169)
- The Junctional Adhesion Molecule JAML Is a Costimulatory Receptor for Epithelial γδ T Cell Activation (2010) (165)
- Skin γδ T‐cell functions in homeostasis and wound healing (2007) (164)
- γδ T cell–induced hyaluronan production by epithelial cells regulates inflammation (2005) (152)
- Limited diversity of T-cell receptor gamma-chain expression of murine Thy-1+ dendritic epidermal cells revealed by V gamma 3-specific monoclonal antibody. (1989) (147)
- An innate view of γδ T cells (1997) (138)
- T Cell Receptor (TCR)-induced Death of Immature CD4+CD8+ Thymocytes by Two Distinct Mechanisms Differing in Their Requirement for CD28 Costimulation: Implications for Negative Selection in the Thymus (1997) (133)
- The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. (2012) (127)
- Positive and Negative Regulation of V(D)J Recombination by the E2A Proteins (1999) (127)
- Functions of skin-resident γδ T cells (2011) (127)
- Dendritic epidermal T cells regulate skin antimicrobial barrier function. (2013) (124)
- A Keratinocyte-Responsive γδ TCR Is Necessary for Dendritic Epidermal T Cell Activation by Damaged Keratinocytes and Maintenance in the Epidermis1 (2004) (123)
- The Molecular Interaction of CAR and JAML Recruits the Central Cell Signal Transducer PI3K (2010) (120)
- Skin gammadelta T-cell functions in homeostasis and wound healing. (2007) (109)
- A Role for CD81 in Early T Cell Development (1996) (106)
- Developmental expression of the αIELβ7 integrin on T cell receptor γδ and T cell receptor αβ T cells (1994) (98)
- The immunobiology of T cells with invariant gamma delta antigen receptors. (1991) (91)
- Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice. (1997) (90)
- Cutting Edge: Dendritic Epidermal γδ T Cell Ligands Are Rapidly and Locally Expressed by Keratinocytes following Cutaneous Wounding (2012) (84)
- A keratinocyte-responsive gamma delta TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis. (2004) (83)
- Gammadelta T cells in host defense and epithelial cell biology. (1998) (78)
- γδ T Cell Homeostasis Is Controlled by IL-7 and IL-15 Together with Subset-Specific Factors1 (2005) (76)
- Regulation of skin cell homeostasis by gamma delta T cells. (2004) (71)
- Integrin α6Aβ1 Induces CD81-dependent Cell Motility without Engaging the Extracellular Matrix Migration Substrate (1997) (70)
- CD81 and CD28 Costimulate T Cells Through Distinct Pathways1 (2000) (69)
- B lymphocyte activation: Entry into cell cycle is accompanied by decreased expression of IgD but not IgM (1983) (68)
- Activation and function of γδ T cells (1994) (67)
- IL-1β–Dependent Activation of Dendritic Epidermal T Cells in Contact Hypersensitivity (2014) (65)
- Skin-Resident T Cells Sense Ultraviolet Radiation–Induced Injury and Contribute to DNA Repair (2014) (64)
- Axon growth and guidance genes identify T‐dependent germinal centre B cells (2008) (58)
- Cell Surface Structures Involved in T Cell Activation (1984) (56)
- Epithelial and mucosal γδ T cells (2006) (56)
- Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response (2011) (53)
- Reduced gut intraepithelial lymphocytes in VLA1 null mice. (2000) (53)
- Preferential Activation of an IL-2 Regulatory Sequence Transgene in TCRγδ and NKT Cells: Subset-Specific Differences in IL-2 Regulation1 (2004) (50)
- T-cell effector mechanisms: γδ and CD1d-restricted subsets (2003) (50)
- An innate view of gamma delta T cells. (1997) (50)
- Phenotypic and functional analysis of γδ T cell receptor-positive murine dendritic epidermal clones (1989) (48)
- Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells (2017) (48)
- Epithelial cells and their neighbors. III. Interactions between intraepithelial lymphocytes and neighboring epithelial cells. (2005) (44)
- All hands on DE(T)C: Epithelial-resident γδ T cells respond to tissue injury. (2015) (44)
- Molecular and cellular biology of dendritic epidermal T cells. (1996) (43)
- Epithelial and mucosal gamma delta T cells. (2006) (41)
- Characterization of an anti-Ly-6 monoclonal antibody which defines and activates cytolytic T lymphocytes. (1988) (41)
- Characterization of the thyroid microsomal antigen, and its relationship to thyroid peroxidase, using monoclonal antibodies. (1988) (41)
- Protection against colitis by CD100 dependent modulation of intraepithelial γδ T lymphocyte function (2013) (39)
- mIgM:mIgD ratios on B cells: mean mIgD expression exceeds mIgM by 10-fold on most splenic B cells. (1984) (39)
- Murine T cells with invariant gamma delta antigen receptors: origin, repertoire, and specificity. (1991) (35)
- Dendritic epidermal T-cell activation. (2005) (33)
- A role for epithelial γδ T cells in tissue repair (2000) (32)
- Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation. (2004) (32)
- Molecular aspects of epithelial γδ T cell regulation. (2011) (32)
- NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity (2015) (31)
- Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. (1994) (29)
- Cross‐talk between intraepithelial γδ T cells and epithelial cells (2013) (26)
- The Role of Tissue-resident γδ T Cells in Stress Surveillance and Tissue Maintenance (2020) (22)
- Integrin alpha 6A beta 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate. (1997) (21)
- T-cell effector mechanisms: gammadelta and CD1d-restricted subsets. (2003) (20)
- Antibodies to the L3T4 and Lyt-2 molecules interfere with antigen receptor-driven activation of cloned murine T cells. (1987) (19)
- Gamma delta T cells in murine epithelia: origin, repertoire, and function. (1991) (19)
- Enrichment of viable lymphocytes in defined cycle phases by sorting on the basis of pulse width of axial light extinction. (1982) (19)
- Characterization of murine cytolytic-helper hybrid T cell clones (1987) (16)
- A role for epithelial gamma delta T cells in tissue repair. (2000) (15)
- Frontline T cells: gammadelta T cells and intraepithelial lymphocytes. (2007) (13)
- Coreceptors and Their Ligands in Epithelial γδ T Cell Biology (2018) (12)
- Identification of a brain theta-positive, secretory cell from hematopoietic tissues. (1981) (12)
- Expression and function of cd3 on murine thymocytes (1988) (12)
- Multiple Receptor-Ligand Interactions Direct Tissue-Resident γδ T Cell Activation (2014) (11)
- EPCR: a stress trigger for γδ T cells (2012) (10)
- The role of intraepithelial γδ T cells: a gut-feelling (1999) (10)
- Innate functions of epithelial gamma delta T cells. (1998) (9)
- Activation and function of gamma delta T cells. (1994) (9)
- Molecular insights into γδ T cell costimulation by an anti-JAML antibody. (2011) (9)
- Immunology: Oiling the wheels of autoimmunity (2014) (9)
- Limited diversity of T-cell receptor y-chain expression of murine Thy-1+ dendritic epidermal cells revealed by Vy3-specific monoclonal antibody (2003) (8)
- Phenotypic and functional analysis of gamma delta T cell receptor-positive murine dendritic epidermal clones. (1989) (7)
- The role of intraepithelial gammadelta T cells: a gut-feeling. (1999) (6)
- T-Cell Development: T-cell lineage commitment revisited (1995) (6)
- Monoclonal antibodies to human trabecular endothelium. A preliminary report on production and characterization. (1986) (6)
- JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy (2021) (6)
- Introduction to Cellular Immunology Special Issue on γδ T cells. (2015) (5)
- Koch's postulates and the molecular biology of T-cell function. (1988) (5)
- Degradable Hydrogels for the Delivery of Immune-modulatory Proteins in the Wound Environment. (2020) (5)
- cDNA Sequence and Fab Crystal Structure of HL4E10, a Hamster IgG Lambda Light Chain Antibody Stimulatory for γδ T Cells (2011) (5)
- Intraepithelial gamma delta T cells exposed by functional genomics (2001) (4)
- A role for epithelial γδ T cells in tissue repair (2009) (4)
- ENTPD1(CD39) expression inhibits ultraviolet radiation-induced DNA damage repair via purinergic signaling and is associated with metastasis in human cutaneous squamous cell carcinoma. (2021) (4)
- Interleukin-2 differentially regulates IL-2 receptors on murine cloned cytolytic and helper T cells. (1986) (4)
- Costimulating epithelial γδ T Cells (2011) (3)
- Molecular Insights into gamma delta T Cell Costimulation by an Anti-JAML Antibody (2011) (3)
- Innate Functions of Epithelial γδ T Cells (1998) (3)
- Hspa8 and ICAM‐1 as damage‐induced mediators of γδ T cell activation (2021) (3)
- Specialized Antitumor Functions for Skin γδ T Cells (2018) (3)
- Effects of anti-Lyt-2 and anti-L3T4 monoclonal antibodies on the function of cytotoxic T lymphocyte/helper T lymphocyte hybrid T cell clones. (1988) (2)
- Intraepithelial T cells exposed by functional genomics (2001) (2)
- γδ T cells and IgE team up to prevent tumors (2018) (2)
- T CELLS WITH INVARIANT yb ANTIGEN RECEPTORS (1991) (2)
- B1 and B2 kinin receptor blockade improves psoriasis‐like disease (2020) (2)
- Visualizing skin {gamma}{delta} T cell antigen expression during wound repair (2008) (1)
- TCR-ligand interactions are required for murine epidermal Vγ3Vδ1 T cell development (2019) (1)
- Anti-L3T4 monoclonal antibody inhibits T-cell activation by anti-T-cell receptor antibody through a pathway not involving "associative recognition". (1987) (1)
- γδ T cells & intraepithelial lymphocytes (2007) (1)
- Novel functional roles for JAML and CAR in epithelial {gamma}{delta} T cell-specific costimulation (2009) (1)
- Introduction: Dendritic epidermal T cells (1996) (1)
- Dendritic Epidermal T Cells Promote Wound Healing by Production of Vascular Endothelial Growth Factor Mediated by HIF‐1α Signaling (2008) (1)
- Function and Specificity of Γ/Δ T Cells. Based on a Workshop Held 14-16 October 1990, Schloss Elmau, Bavaria, Germany.K. Pfeffer , K. Heeg , H. Wagner , G. Riethmuller (1992) (0)
- γδ T cells and IgE team up to prevent tumors (2018) (0)
- Visualizing skin γδ T cell antigen expression during wound repair (2008) (0)
- Factors and IL-15 Together with Subset-Specific T Cell Homeostasis Is Controlled by IL-7 δγ (2005) (0)
- Role of human skin resident T cells in wound healing (B116) (2007) (0)
- Novel functional roles for JAML and CAR in epithelial γδ T cell-specific costimulation (135.68) (2009) (0)
- Epithelial γδ T cell‐specific costimulation mediated by JAML‐CAR interactions (2008) (0)
- The role of JAML-CAR costimulation in gamma delta T cell-mediated repair of the intestinal epithelium (2020) (0)
- Woundingby Keratinocytes following Cutaneous Ligands Are Rapidly and Locally Expressed T Cell d g Cutting Edge: Dendritic Epidermal (2012) (0)
- Multiple receptor-ligand interactions direct activation of epidermal γδ T cells in response to keratinocyte damage (63.7) (2011) (0)
- Development of immunology laboratory techniques for high school chemistry students (1996) (0)
- Regulation of Activation of Cloned Murine T Cells (1986) (0)
- 494 UV-induced CD39 expression promotes epidermal DNA damage and development of cutaneous squamous cell carcinoma (2019) (0)
- Analysis of peripheral blood γδ T cell levels in inflammatory bowel disease (1998) (0)
- Epithelial and bone marrow derived sources of Cd1d contribute to wound repair (2016) (0)
- JAML-CAR – A Mechanism of T Cell Antitumor Immunity (2019) (0)
- Epithelial: T Cell Interactions (2009) (0)
- CD100 modulation of intraepithelial lymphocyte function during colitis: P-0012 (2007) (0)
- Using differentiated instruction to teach immunological concepts to a diverse group of learners. (51.6) (2011) (0)
- Skin-resident T cells limit UV damage through sensing the danger signal ATP (P3246) (2013) (0)
- γδ T cell activation in response to a keratinocyte wound signature (2019) (0)
- 741 UV-induced CD39 expression on immunosuppressive memory T cells in human cutaneous squamous cell carcinoma (2019) (0)
- 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells (2018) (0)
- Author response: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells (2017) (0)
- Endothelial Protein C Receptor regulates skin gamma delta T cell functions (2016) (0)
- Visualizing the rapid and localized keratinocyte expression of dendritic epidermal T cell antigens in response to wounding (93.3) (2009) (0)
- Multiple receptor-ligand interactions direct activation of epidermal {gamma}{delta} T cells in response to keratinocyte damage (2011) (0)
- The Biology of γδ T Cells: What Is the Relationship between γδ T Cells and Cancer? Will an Increased Number and/or Function of γδ T Cells Result in Lower Cancer Incidence? (2005) (0)
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