Werner Arber | Academic Influence

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Werner Arber

Biology

#97

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#174

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Microbiology

#47

World Rank

#63

Historical Rank

Genetics

#75

World Rank

#108

Historical Rank

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Biology

Werner Arber's Degrees

PhD Natural Sciences University of Geneva

Why Is Werner Arber Influential?

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Areas of Specialization: Microbiology
Werner Arber is a geneticist and microbiologist. He studied at the Swiss Federal Institute of Technology and the University of Geneva. His doctorate was completed at the University of Geneva, where he studied electron microscopy and lambda bacteriophages.

Arber has worked with students, scientists and researchers at the University of Southern California, the University of Geneva, the University of California, Berkeley and the University of Basel.

He was among the first to work in the University of Basel’s new interdisciplinary research center, the Biozentrum. His work on restriction endonucleases (and arguably his experience working with Daisy Roulland-Dussoix, a PhD student) led to a shared Nobel Prize in Physiology or Medicine.

He has provided exceptional scientific leadership, serving as a member of the World Knowledge Dialogue Scientific Board and the Pontifical Academy of Sciences. In 2011, he became the first protestant to be appointed as President of the Pontifical Academy of Sciences. He is co-founder of the World Cultural Council and a fellow of the American Academy of Arts and Sciences.

Arber has been generous with his time, sharing his expertise and knowledge with future scientists through the Lindau Nobel Laureate Meetings. Through these interactions, he is able to mentor young scientists and nurture a spirit of inquiry and deep curiosity.

Featured in Top Influential Biologists Today

According to Wikipedia, Werner Arber is a Swiss microbiologist and geneticist. Along with American researchers Hamilton Smith and Daniel Nathans, Werner Arber shared the 1978 Nobel Prize in Physiology or Medicine for the discovery of restriction endonucleases. Their work would lead to the development of recombinant DNA technology.

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Werner Arber's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

DNA modification and restriction. (1969) (569)
Host specificity of DNA produced by Escherichia coli. 9. Host-controlled modification of bacteriophage fd. (1966) (362)
Genetic variation: molecular mechanisms and impact on microbial evolution. (2000) (286)
Genomic evolution during a 10,000-generation experiment with bacteria. (1999) (269)
Host specificity of DNA produced by Escherichia coli. II. Control over acceptance of DNA from infecting phage lambda. (1962) (206)
Transduction of chromosomal genes and episomes in Escherichia coli. (1960) (189)
Host-Controlled Modification of Bacteriophage (1965) (180)
Experimental Methods for Use with Lambda (1983) (177)
Host specificity of DNA produced by Escherichia coli, X. In vitro restriction of phage fd replicative form. (1962) (175)
Host specificity of DNA produced by Escherichia coli (1964) (175)
Electron microscopical studies of phage multiplication. I. A method for quantitative analysis of particle suspensions. (1957) (166)
Insertion sequence-related genetic variation in resting Escherichia coli K-12. (1994) (146)
Genetic manipulation : impact on man and society (1984) (141)
Nucleotide sequence of IS26, a new prokaryotic mobile genetic element. (1983) (131)
CHAPTER 4 – Prokaryotic IS Elements (1983) (119)
Mutational analysis of a prokaryotic recombinational enhancer element with two functions. (1989) (113)
Host specificity of DNA produced by Escherichia coli. I. Host controlled modification of bacteriophage lambda. (1962) (112)
HOST SPECIFICITY OF DNA PRODUCED BY Escherichia coli, XI. In vitro MODIFICATION OF PHAGE FD REPLICATIVE FORM (1968) (107)
Host-controlled modification of bacteriophage. (1963) (104)
HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA COLI V . THE ROLE OF METHIONINE IN THE PRODUCTION OF HOST SPECIFICITY. (1965) (103)
Dynamics of IS-related genetic rearrangements in resting Escherichia coli K-12. (1995) (99)
A site‐specific, conservative recombination system carried by bacteriophage P1. Mapping the recombinase gene cin and the cross‐over sites cix for the inversion of the C segment. (1982) (89)
Host specificity of DNA produced by Escherichia coli. XV. The role of nucleotide methylation in in vitro B-specific modification. (1972) (85)
Two DNA antirestriction systems of bacteriophage P1, darA, and darB: characterization of darA- phages. (1987) (84)
Horizontal Gene Transfer among Bacteria and Its Role in Biological Evolution (2014) (83)
DNA restriction--modification genes of phage P1 and plasmid p15B. Structure and in vitro transcription. (1983) (79)
DNA modification and restriction. (1974) (78)
Nucleotide sequence of the prokaryotic mobile genetic element IS30. (1984) (78)
Rearrangements of genetic material in Escherichia coli as observed on the bacteriophage P1 plasmid. (1979) (74)
An Escherichia coli mutant which inhibits the injection of phage λ DNA (1974) (73)
Phage λ DNA injection into Escherichia coli pel− mutants is restored by mutations in phage genes V or H (1976) (64)
Evolution of prokaryotic genomes. (1993) (58)
DNA inversion regions Min of plasmid p15B and Cin of bacteriophage P1: evolution of bacteriophage tail fiber genes (1992) (58)
TEMPERATURE-SENSITIVE MUTANTS OF COLIPHAGE LAMBDA. (1964) (57)
Polylysogeny for Bacteriophage Lambda. (1960) (55)
Promotion and limitation of genetic exchange. (1979) (55)
Functional characterization of the prokaryotic mobile genetic element IS26 (2004) (52)
Host specificity of DNA produced by Escherichia coli. XII. The two restriction and modification systems of strain 15T-. (1970) (52)
Three functions of bacteriophage P1 involved in cell lysis (1996) (51)
Site-specific DNA inversion is enhanced by a DNA sequence element in cis. (1985) (50)
Terminal inverted repeats of insertion sequence IS30 serve as targets for transposition (1997) (49)
The insertion element IS1 is a natural constituent of coliphage P1 DNA. (1978) (49)
Elements for a theory of molecular evolution. (2003) (47)
HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA COLI. IV. HOST SPECIFICITY OF INFECTIOUS DNA FROM BACTERIOPHAGE LAMBDA. (1965) (44)
The N-terminal domain of the insertion sequence 30 transposase interacts specifically with the terminal inverted repeats of the element. (1990) (44)
Plaque-forming transducing bacteriophage P1 derivatives and their behaviour in lysogenic conditions. (1976) (42)
Physical mapping of BglII, BamHI, EcoRI, HindIII and PstI Restriction fragments of bacteriophage P1 DNA (1977) (40)
Genesis and natural history of IS-mediated transposons. (1981) (40)
E. coli K-12 pel mutants, which block phage λ DNA injection, coincide with ptsM, which determines a component of a sugar transport system (1978) (40)
IS2 insertion is a major cause of spontaneous mutagenesis of the bacteriophage P1: non‐random distribution of target sites. (1983) (39)
Gene organization and target specificity of the prokaryotic mobile genetic element IS26 (2004) (39)
The kanamycin resistance transposon Tn2680 derived from the R plasmid Rts1 and carried by phage P1Km has flanking 0.8-kb-long direct repeats. (1982) (38)
Bent DNA is needed for recombinational enhancer activity in the site-specific recombination system Cin of bacteriophage P1. The role of FIS protein. (1989) (38)
Erweiterung des Wirtsbereiches des Bakteriophagen λauf Escherichia coli B (1961) (37)
Elements in microbial evolution (1991) (37)
Formation of the tandem repeat (IS30)2 and its role in IS30-mediated transpositional DNA rearrangements (1993) (36)
Genetic engineering compared to natural genetic variations. (2010) (35)
Bleomycin-resistance gene derived from the transposon Tn5 confers selective advantage to Escherichia coli K-12. (1991) (34)
Die Struktur des Schwanzes der Phagen T2 und T4 und der Mechanismus der irreversiblen Adsorption (1955) (33)
Host specificity of DNA produced by Escherichia coli (1965) (31)
Promotion of RNA transcription on the insertion element IS30 of E. coli K12. (1985) (30)
Terminal inverted repeats of prokaryotic transposable element IS186 which can generate duplications of variable length at an identical target sequence. (1986) (29)
Study of the properties of seven defective-lysogenic strains derived from Escherichia coli K12 (lambda). (1958) (29)
Accessory genes in the darA operon of bacteriophage P1 affect antirestriction function, generalized transduction, head morphogenesis, and host cell lysis. (1998) (29)
Plaque forming specialized transducing phage P1: Isolation of P1CmSmSu, a precursor of P1Cm (1977) (28)
The sequence of the bacteriophage P1 genome region serving as hot target for IS2 insertion. (1983) (28)
Vector for IS element entrapment and functional characterization based on turning on expression of distal promoterless genes. (1996) (27)
Is the IS1-flanked r-determinant of the R plasmid NR1 a transposon? (1981) (26)
Transposable element IS1 intrinsically generates target duplications of variable length. (1985) (26)
The bacteriophage P1 site-specific recombinase cin: recombination events and DNA recognition sequences. (1984) (24)
Does the insertion element IS1 transpose preferentially into A+T-rich DNA segments? (2004) (24)
Promotion and limitation of genetic exchange (1979) (23)
Characterization of in vitro constructed IS30-flanked transposons. (1989) (23)
Generation of genetic diversity by DNA rearrangements in resting bacteria (1994) (23)
The Min DNA inversion enzyme of plasmid p15B of Escherichia coli 15T−: a new member of the Din family of site‐specific recombinases (1990) (22)
IS30, a new insertion sequence of Escherichia coli K12 (2004) (22)
Site-specific DNA recombination system Min of plasmid p15B: a cluster of overlapping invertible DNA segments. (1990) (22)
Bacteriophage P1 gene 10 encodes a trans-activating factor required for late gene expression (1991) (22)
An Escherichia coli mutant which inhibits the injection of phage lambda DNA. (1974) (21)
A Beginner’s Guide to Lambda Biology (1983) (21)
APPENDIX I Spontaneous Mutations in the Escherichia coli Prophage P1 and IS-Mediated Processes (1981) (21)
The generation of variation in bacterial genomes (2004) (21)
Host specificity of DNA produced by Escherichia coli. XIV. The role of nucleotide methylation in in vivo B-specific modification. (1972) (21)
Genetic Variation and Molecular Evolution (2006) (20)
[Mutational loss of the B-specific restriction in bacteriophage fd]. (1967) (19)
Sequence relations among the IncY plasmid p15B, P1, and P7 prophages. (1986) (19)
Occurrence and properties of composite transposon Tn2672: evolution of multiple drug resistance transposons (1982) (19)
The Major Histocompatibility Antigens in Various Species (1970) (18)
Phage lambda DNA injection into Escherichia coli pel- mutants is restored by mutations in phage genes V or H. (1976) (17)
Gene organization in the multiple DNA inversion region min of plasmid p15B of E.coli 15T-: assemblage of a variable gene. (1991) (17)
Mechanisms in microbial evolution. (1990) (17)
Bacteriophage P1 tail-fibre and dar operons are expressed from homologous phage-specific late promoter sequences. (1989) (16)
Involvement of Gene Products in Bacterial Evolution (1999) (16)
Mutational analysis of the bacteriophage P1 late promoter sequence Ps. (1992) (16)
ON THE HOST-CONTROLLED MODIFICATION OF BACTERIOPHAGE LAMBDA. (1963) (16)
Host-controlled restriction and modification of filamentous 1- and F-specific bacteriophages. (1969) (15)
Physical analysis of the genomes of hybrid phages between phage P1 and plasmid p15B. (1983) (15)
Biological evolution: lessons to be learned from microbial population biology and genetics. (2004) (15)
Host specificity of DNA produced by Escherichia coli. 8. Its acquisition by phage lambda and its persistence through consecutive growth cycles. (1966) (15)
On the segregation of IS1-mediated cointegrates between bacteriophage P1 DNA and plasmid pBR322 derivatives (1982) (15)
On the role of IS1 in the formation of hybrids between the bacteriophage P1 and the R plasmid NR1 (2004) (14)
The characterization of terminators of RNA transcription on IS30 and an analysis of their role in IS element-mediated polarity. (1986) (14)
A cloned DNA fragment from bacteriophage P1 enhances IS2 insertion (1987) (14)
Parental fd DNA is efficiently transferred into progeny bacteriophage particles even at low multiplicity of infection. (1969) (12)
A transcriptional terminator sequence in the prokaryotic transposable element IS1 (1987) (12)
Organization of the bacteriophage P1 tail-fibre operon. (1989) (12)
The impact of science and technology on the civilization. (2009) (12)
Bacteriophage P1 gene 10 is expressed from a promoter-operator sequence controlled by C1 and Bof proteins (1992) (12)
Roots, strategies and prospects of functional genomics (2002) (11)
Cointegrates between bacteriophage P1 DNA and plasmid pBR322 derivatives suggest molecular mechanisms for P1-mediated transduction of small plasmids (2004) (11)
Random mutagenesis using degenerate oligodeoxyribonucleotides. (1988) (11)
Multiple physical differences in the genome structure of functionally related bacteriophages P1 and P7 (1979) (10)
Biodiversity as a source for synthetic domestication of useful specific traits (2013) (10)
Molecular mechanisms driving Darwinian evolution (2008) (9)
Bacteriophage P1 derivatives unaffected in their growth by a large inversion or by IS insertions at various locations. (1985) (9)
The evolutionary strategy of DNA acquisition as a possible reason for a universal genetic code. (2006) (9)
Morphologie von Leberglykogen (1957) (8)
On the Role of IS 1 in the Formation of Hybrids between the Bacteriophage P 1 and the R Plasmid NR 1 (8)
Molecular Darwinism: The Contingency of Spontaneous Genetic Variation (2011) (8)
Chapter 4 Host-controlled Variation (1971) (8)
Restriction endonucleases. (1978) (8)
Bacterial "inserted sequence" elements and their influence on genetic stability and evolution. (1983) (7)
Cin-mediated recombination at secondary crossover sites on the Escherichia coli chromosome (1995) (7)
APPENDIX II Analysis of Transposition of IS1-kan and Its Relatives (1981) (7)
Amplification of drug resistance genes flanked by inversely repeated IS1 elements: involvement of IS1-promoted DNA rearrangements before amplification (1987) (7)
Dual Nature of the Genome: Genes for the Individual Life and Genes for the Evolutionary Progress of the Population (2005) (7)
Lack of hotspot targets: a constraint for IS30 transposition in Salmonella. (1999) (6)
DNA restriction-modification enzymes of phage P1 and plasmid p15B (1983) (6)
Evolution of prokaryotic genomes. (2002) (6)
Gene products with evolutionary functions (2005) (6)
Evolutionary relevance of genetic rearrangements involving plasmids. (1985) (6)
HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA COLI. 3. EFFECTS ON TRANSDUCTION MEDIATED BY LAMBDA DG. (1964) (5)
What is the function of DNA restriction enzymes (1977) (4)
Crossover sites cix for inversion of the invertible DNA segment C on the bacteriophage P7 genome. (1985) (4)
Towards a Sustainable Use of Natural Resources by Respecting the Laws of Nature (2016) (4)
Genome fusion mediated by the site specific DNA inversion system of bacteriophage P1 (2004) (4)
Genetic Variation and Molecular Darwinism (2011) (4)
An active variant of the prokaryotic transposable element IS903 carries an amber stop codon in the middle of an open reading frame (2004) (4)
Systemic aspects of biological evolution. (2009) (4)
MOLECULAR EVOLUTION: COMPARISON OF NATURAL AND ENGINEERED GENETIC VARIATIONS (2013) (4)
Société Suisse de Microbiologie/ Schweizerische Mikrobiologische Gesellschaft (1952) (3)
Genetic engineering represents a safe approach for innovations improving nutritional contents of major food crops (2017) (3)
Mechanisms involved in the formation of plaque-forming derivatives from over-sized hybrid phages between bacteriophage P1 and the R plasmid NR1 (1987) (3)
The Scientific Legacy of the 20th Century : the Proceedings of the Plenary Session, 28 October – 1 November, 2010 (2011) (2)
On the Origin of Genetic Diversity (1995) (2)
Host specificity of DNA produced by Escherichia coli. 13. Breakdown of cellular DNA upon growth in ethionine of strains with r plus-15, r plus-P1 or r plus-N3 restriction phenotypes. (1970) (2)
Host specificity of DNA produced by Escherichia coli. XVI. Phage lambda DNA carries a single site of affinity for A-specific restriction and modification. (1972) (2)
[Origin and properties of type A host specificity in Escherichia coli]. (1969) (2)
Host specificity of DNA produced byEscherichia coli (1966) (2)
Contemplations on genes and biological functions. (1991) (1)
[Research on the fine structure of a bacteriophage with the help of oxydative decomposition]. (1955) (1)
The 2009 Lindau Nobel Laureate Meeting: Werner Arber, Physiology or Medicine 1978 (2010) (1)
Genetically encoded generators of genetic variants. (2009) (1)
[Not all risks of medical progress and biological basic research are predictable]. (1980) (1)
Evolutionary Interplay Between Spontaneous Mutation and Selection: Aleatoric Contributions of Molecular Reaction Mechanisms (1994) (1)
STOCHASTIC GENETIC VARIATIONS AND THEIR ROLE IN BIOLOGICAL EVOLUTION (2013) (1)
Involvement of transposable elements in the formation of hybrid phages between bacteriophage P1 and the R plasmid NR1 (1987) (1)
"Investing in Science, Technology and Innovation: Challenges and Opportunities for Parliaments" (2007) (1)
[THE ROLE OF DNA METHYLATION IN THE CONTROL MY THE HOST OF MODIFICATION OF THE BACTERIOPHAGE]. (1965) (1)
Diversity of Life in a Changing World (1995) (1)
Plaque-Forming Recombinants between Bacteriophage P1 and R factor NR1 and their Behaviour in Lysogenic Conditions (1974) (1)
[Defectiveness of lambda phage transductor]. (1957) (1)
[Enlargement of the host area of bacteriophage lambda for Escherichia coli B]. (1961) (1)
Erratum: Host Specificity of DNA Produced by Escherichia coli (1970) (1)
Restriction Enzymes: From Their Discovery to Their Applications (2012) (1)
Index reriim ad Vol. XXX (1967) (0)
[In vitro modification of the replicative form of fd bacteriophage]. (1969) (0)
Natural mechanisms of interspecific gene transfer (1987) (0)
Host-Controlled Modification of DNA (1968) (0)
Letter from Werner Arber to Joshua Lederberg (1959) (0)
3 The theory of molecular evolution and its medical implications (2005) (0)
Letter from Werner and Silvia Arber to Joshua Lederberg (1978) (0)
[Biological specificities of desoxyribonucleic acid]. (1962) (0)
[Factors of antibiotic resistance. Viewpoint of the molecular geneticist]. (1967) (0)
Natural Strategies of Spontaneous Genetic Variation: The Driving Force of Biological Evolution (2018) (0)
Incompatibilities and Restrictions in Plasmid Transmission (2008) (0)
ASYMMETRIC HYDROFORMYLATION OF OLEFINIC HYDROCARBONS BY PLATINUM CATALYSTS (1978) (0)
Reversion of a truncated gene for ampicillin resistance by genetic rearrangements in Escherichia coli K12 (2004) (0)
Bioengineering at the Interface between Science and Society (2011) (0)
DNA fingerprinting. (2020) (0)
Nobel Laureate's views on higher education (2006) (0)
Transdisciplinarity in Science Education and in Science Communication (2020) (0)
Complexity and Analogy in Science : Theoretical, Methodological and Epistemological Aspects ; The Proceedings of the Plenary Session, 5-7 November 2012 (2015) (0)
Untersuchung der Feinstruktur eines Bakteriophagen mit Hilfe von oxydativem Abbau (1955) (0)
NUCLEOTIDE SEQUENCE SPECIFICITY OF RESTRICTION ENDONUCLEASES (1999) (0)
Schweizerische Mikrobiologische Gesellschaft/ Société Suisse de Microbiologie (2004) (0)
Current Topics in Microbiology and Immunology (1981) (0)
Closing Session: Future Directions: Strategies and Perspectives (1999) (0)
Referees 1997 (1997) (0)
Buchbesprechungen-BookReviews-LivresNouveaux (1951) (0)
Research letterStructures of oversized genomes of phage P1 derivatives carrying lac genes of Escherichia coli K12 (1987) (0)
THE IMPACT OF MICROBIAL GENETICS ON THE DEVELOPMENT OF GENOMICS AND BIOTECHNOLOGY (2013) (0)
Report of the CGIAR Science Partnership Committee (2001) (0)
Molecular Darwinism and its Relevance for Translational Genetic Research (2011) (0)
In vitro Modifikation der replikativen Form des Bakteriophagen fd (1969) (0)
Stability and alteration of insertion sequence IS1-mediated chloramphenicol transposons (1981) (0)
Normal expression of the viral gene N interferes with growth of bacteriophage lambda in Escherichia coli 15T-. (1977) (0)
Ernst Wïesmann zum 60. Geburtstag (1969) (0)
Human-Nature Co-Evolution (2014) (0)
Letter from Werner Arber to Joshua and Esther Lederberg (1958) (0)
The Proceedings of the Plenary Session on Predictability in Science: Accuracy and Limitations: 3-6 November 2006 (2008) (0)
Ursprung und Eigenschaften des Wirtsspezifittstypus A in Escherichia coli (1969) (0)
Index autorum ad Vol. XXX (1967) (0)
Normal expression of the viral gene N interferes with growth of bacteriophage λ in Escherichia coli 15T- (1977) (0)
Today’s molecular biological research. (2010) (0)
FROM MICROBIAL GENETICS TO MOLECULAR DARWINISM AND BEYOND (2013) (0)
Letter from Werner Arber to Esther Lederberg (1958) (0)
Book Review – Buchbesprechung – Livre nouveau (1974) (0)
DNA inversion mediated by the r-determinant of plasmid NR1: Evidence for the intramolecular replicative transposition of a 23 kb IS1-flanked transposon? (1986) (0)
Structures of oversized genomes of phage P1 derivatives carrying lac genes of Escherichia coli K12 (1987) (0)
Mitglieder-Liste der Schweizerischen Mikrobiologischen Gesellschaft (1951) (0)
Complexity of Life and Its Dependence on the Environment (2020) (0)
Transduction By P1 of Gal and Lp Regions From Heterogenotic Donors (1959) (0)
Roots, promotion and impact of technological innovation (2008) (0)
Insight into the natural potency to evolve, can indicate safe procedures for genetic engineering (2012) (0)
Microbiology: impact on research in life sciences. (2001) (0)
Concluding Remarks (1999) (0)
Self-Organization of the Biological Evolution (2019) (0)

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