Werner Sieghart

Q: What Schools Are Affiliated With Werner Sieghart

Werner Sieghart is affiliated with the following schools: University of Innsbruck, Medical University of Vienna, Yale University, Normandy University Group, University of Oxford, University of Salzburg, University of Turku, University of Vienna

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Werner Sieghart

Physics

#4130

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#5727

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Physics

Werner Sieghart's Degrees

PhD Physics University of Vienna
Masters Physics University of Vienna
Bachelors Physics University of Vienna

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Werner Sieghart's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. (1995) (1365)
International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. (1998) (1321)
GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain (2000) (1232)
International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update (2008) (974)
Subunit composition, distribution and function of GABA(A) receptor subtypes. (2002) (901)
Segregation of Different GABAA Receptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells (1998) (886)
GABAA receptors: Subtypes provide diversity of function and pharmacology (2009) (883)
GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. (2000) (669)
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. (1999) (528)
Stoichiometry and Assembly of a Recombinant GABAA Receptor Subtype (1997) (505)
Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells. (1996) (404)
Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord (1996) (393)
GABAA receptors: ligand-gated Cl- ion channels modulated by multiple drug-binding sites. (1992) (383)
GABAA receptor subunits in the rat hippocampus I: Immunocytochemical distribution of 13 subunits (1997) (350)
Ligand-Gated Ion Channel Subunit Partnerships: GABAAReceptor α6 Subunit Gene Inactivation Inhibits δ Subunit Expression (1997) (319)
Molecular heterogeneity of benzodiazepine receptors (1980) (309)
Structure, pharmacology, and function of GABAA receptor subtypes. (2006) (302)
Structure and subunit composition of GABAA receptors (1999) (300)
Bidirectional Alterations of GABAA Receptor Subunit Peptide Levels in Rat Cortex During Chronic Ethanol Consumption and Withdrawal (1997) (277)
GABAA receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain (2002) (231)
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein. (1980) (228)
A propofol binding site on mammalian GABAA receptors identified by photolabeling (2013) (214)
Subunit Composition and Quantitative Importance of Hetero-oligomeric Receptors: GABAA Receptors Containing α6 Subunits (1998) (210)
Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. (2002) (200)
GABAA Receptor Phosphorylation and Functional Modulation in Cortical Neurons by a Protein Kinase C-dependent Pathway* (2000) (199)
Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain (2013) (194)
Photoaffinity Labeling of Benzodiazepine Receptor Proteins with the Partial Inverse Agonist [3H]Ro 15–4513: A Biochemical and Autoradiographic Study (1987) (187)
Colocalization of multiple GABAA receptor subtypes with gephyrin at postsynaptic sites (2000) (177)
The γ2 Subunit of the GABAA Receptor is Concentrated in Synaptic Junctions Containing the α1 and β 2 3 Subunits in Hippocampus, Cerebellum and Globus Pallidus (1996) (177)
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands. (2012) (176)
Distribution of the major γ‐aminobutyric acidA receptor subunits in the basal ganglia and associated limbic brain areas of the adult rat (2001) (172)
GABAA receptor subunits in the rat hippocampus II: Altered distribution in kainic acid-induced temporal lobe epilepsy (1997) (171)
GABA Expression Dominates Neuronal Lineage Progression in the Embryonic Rat Neocortex and Facilitates Neurite Outgrowth via GABAA Autoreceptor/Cl− Channels (2001) (170)
Functional Correlation of GABAA Receptor α Subunits Expression with the Properties of IPSCs in the Developing Thalamus (2000) (164)
Allosteric modulation of GABAA receptors via multiple drug-binding sites. (2015) (161)
Antibodies Specific for GABAA Receptor α Subunits Reveal that Chronic Alcohol Treatment Down‐Regulates α‐Subunit Expression in Rat Brain Regions (1993) (160)
Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze‐fracture replica immunolabelling (2010) (160)
Comparative modeling of GABAA receptors: limits, insights, future developments (2003) (156)
Multiplicity of GABAA--benzodiazepine receptors. (1989) (148)
Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell (1978) (148)
Deficits in Phosphorylation of GABAA Receptors by Intimately Associated Protein Kinase C Activity Underlie Compromised Synaptic Inhibition during Status Epilepticus (2008) (148)
Comparative Models of GABAA Receptor Extracellular and Transmembrane Domains: Important Insights in Pharmacology and Functions⃞ (2005) (140)
GABAA receptor subunits in the rat hippocampus III: altered messenger RNA expression in kainic acid-induced epilepsy (1997) (135)
Binge alcohol drinking is associated with GABAA α2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala (2011) (135)
The alpha 6 subunit of the GABAA receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells (1996) (132)
Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia (1998) (129)
No evidence for in vivo regulation of midbrain serotonin transporter availability by serotonin transporter promoter gene polymorphism (2001) (128)
Altered receptor subtypes in the forebrain of GABAA receptor δ subunit-deficient mice: recruitment of γ2 subunits (2002) (127)
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines (2012) (126)
Gephyrin, the enigmatic organizer at GABAergic synapses (2012) (123)
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to α4/6β3δ GABAA receptors (2006) (121)
Distribution of α1, α4, γ2, and δ subunits of GABAA receptors in hippocampal granule cells (2004) (120)
From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors (2007) (118)
Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the α6 subunit gene (1999) (116)
Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakistani patients (1999) (114)
Differential Regulation of GABAA Receptor Gene Expression by Ethanol in the Rat Hippocampus Versus Cerebral Cortex (1998) (114)
International Union of Basic and Clinical Pharmacology. CVI: GABAA Receptor Subtype- and Function-selective Ligands: Key Issues in Translation to Humans (2018) (111)
Subunit composition and quantitative importance of GABAA receptor subtypes in the cerebellum of mouse and rat (2003) (110)
Synaptic Control of Glycine and GABAA Receptors and Gephyrin Expression in Cultured Motoneurons (1999) (99)
Protein Kinase C Phosphorylation Regulates Membrane Insertion of GABAA Receptor Subtypes That Mediate Tonic Inhibition* (2010) (99)
GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain. (2002) (99)
A Significant Part of Native γ-Aminobutyric AcidAReceptors Containing α4 Subunits Do Not Contain γ or δ Subunits* (1999) (99)
Genome scan for susceptibility loci for schizophrenia and bipolar disorder (2002) (97)
Molecular Basis of the γ-Aminobutyric Acid A Receptor α3 Subunit Interaction with the Clustering Protein Gephyrin* (2011) (97)
European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms. (1998) (96)
Targeted Disruption of the GABAA Receptor δ Subunit Gene Leads to an Up-regulation of γ2Subunit-containing Receptors in Cerebellar Granule Cells* (2001) (94)
The GABAA Receptor α+β− Interface: A Novel Target for Subtype Selective Drugs (2011) (94)
Cultured Hippocampal Pyramidal Neurons Express Two Kinds of GABAA Receptors (2005) (90)
Ectopic expression of the GABAA receptor α6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition (2002) (89)
Affinity of various ligands for benzodiazepine receptors in rat cerebellum and hippocampus. (1984) (89)
Immunohistochemical localization of the α 1, α 2 and α 3 subunit of the GABAA receptor in the rat brain (1991) (88)
Photoaffinity labeling of benzodiazepine receptors with a partial inverse agonist. (1984) (87)
Rat beta 3 subunits expressed in human embryonic kidney 293 cells form high affinity [35S]t-butylbicyclophosphorothionate binding sites modulated by several allosteric ligands of gamma-aminobutyric acid type A receptors. (1995) (86)
Interaction of allosteric ligands with GABAA receptors containing one, two, or three different subunits. (1996) (82)
Association of protein kinase C with GABAA receptors containing α1 and α4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption (2002) (82)
Pharmacological Properties of GABAA Receptors Containing γ1 Subunits (2006) (82)
Genome Scan for Susceptibility Loci for Schizophrenia (2000) (81)
PHARMACOLOGY OF BENZODIAZEPINE RECEPTORS: AN UPDATE (1994) (81)
Increased Expression of GABAA Receptor β‐Subunits in the Hippocampus of Patients with Temporal Lobe Epilepsy (2003) (78)
Unraveling the function of GABAA receptor subtypes (2000) (77)
Protein Kinase Cδ Regulates Ethanol Intoxication and Enhancement of GABA-Stimulated Tonic Current (2008) (76)
TAURINE UPTAKE IN SYNAPTOSOMAL FRACTIONS OF RAT CEREBRAL CORTEX 1 (1975) (76)
GABA(A) receptor subunits in the rat hippocampus II: altered distribution in kainic acid-induced temporal lobe epilepsy. (1997) (76)
Alternate Use of Distinct Intersubunit Contacts Controls GABAA Receptor Assembly and Stoichiometry (2001) (75)
A novel GABAA receptor pharmacology: drugs interacting with the α+β‐ interface (2012) (73)
Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor γ2 subunit (2004) (73)
The citalopram challenge test in patients with major depression and in healthy controls (1999) (71)
Are GABAA Receptors Containing α5 Subunits Contributing to the Sedative Properties of Benzodiazepine Site Agonists? (2008) (71)
Cellular localization and differential distribution of GABAA receptor subunit proteins and messenger RNAs within hypothalamic magnocellular neurons (1995) (70)
GABAA Receptor Assembly (2000) (69)
gamma-Aminobutyric acid, acting through gamma -aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus. (2000) (68)
Deficits in spatial memory correlate with modified γ-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus (2009) (67)
Ca2+ and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue. (1979) (67)
An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models. (2007) (66)
Non‐association of dopamine D4 and D2 receptor genes with personality in healthy individuals (2000) (66)
Various proteins from rat brain, specifically and irreversibly labeled by [3H]flunitrazepam, are distinct α-subunits of the GABA-benzodiazepine receptor complex (1988) (65)
The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus. (1996) (64)
Evidence for the existence of several different α- and β-subunits of the GABA/benzodiazepine receptor complex from rat brain (1989) (63)
Neurosteroid Analog Photolabeling of a Site in the Third Transmembrane Domain of the β3 Subunit of the GABAA Receptor (2012) (63)
Several new benzodiazepines selectively interact with a benzodiazepine receptor subtype (1983) (62)
Possible association between childhood absence epilepsy and the gene encoding GABRB3 (1999) (62)
Irreversible Binding of [3H]Flunitrazepam to Different Proteins in Various Brain Regions (1983) (61)
Distribution of alpha1, alpha4, gamma2, and delta subunits of GABAA receptors in hippocampal granule cells. (2004) (61)
Long-Range Interactions in Neuronal Gene Expression: Evidence from Gene Targeting in the GABAA Receptor β2–α6–α1–γ2 Subunit Gene Cluster (2000) (61)
Light Treatment in Depressive Illness (1986) (61)
Properties of [3H]flunitrazepam binding to different benzodiazepine binding proteins. (1983) (59)
PWZ-029, a compound with moderate inverse agonist functional selectivity at GABAA receptors containing α5 subunits, improves passive, but not active, avoidance learning in rats (2008) (59)
Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure (2010) (59)
Separation of a1, a2 and a3 subunits of the GABAA-benzodiazepine receptor complex by immunoaffinity chromatography (1991) (59)
Postnatal Development of Proteins Associated with Different Benzodiazepine Receptors (1986) (58)
Deep Amino Acid Sequencing of Native Brain GABAA Receptors Using High-Resolution Mass Spectrometry* (2011) (57)
Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models. (2009) (57)
Composition of the GABAA Receptors of Retinal Dopaminergic Neurons (1999) (56)
Benzodiazepine-mediated regulation of α1, α2, β1–3 and γ2 GABAA receptor subunit proteins in the rat brain hippocampus and cortex ∗ Portions of this work have appeared in abstract form: Soc. Neurosci. Abstr. (1996) Abstract 22, 1285. ∗ (1999) (56)
Immunoaffinity purification of gamma-aminobutyric acidA (GABAA) receptors containing gamma 1-subunits. Evidence for the presence of a single type of gamma-subunit in GABAA receptors. (1994) (55)
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptors. (2006) (55)
Clusters of GABAA receptors on cultured hippocampal cells correlate only partially with functional synapses (1999) (54)
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit. (2004) (53)
Immunocytochemical localization of the alpha 1 and beta 2/3 subunits of the GABAA receptor in relation to specific GABAergic synapses in the dentate gyrus. (1995) (53)
Azemiopsin from Azemiops feae Viper Venom, a Novel Polypeptide Ligand of Nicotinic Acetylcholine Receptor* (2012) (52)
Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains (2009) (50)
GABA influences the development of the ventromedial nucleus of the hypothalamus. (2001) (50)
Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits. (2002) (49)
Clustering of Extrasynaptic GABAA Receptors Modulates Tonic Inhibition in Cultured Hippocampal Neurons* (2004) (49)
EVIDENCE FOR SPECIFIC SYNAPTOSOMAL LOCALIZATION OF EXOGENOUS ACCUMULATED TAURINE 1 (1974) (48)
GABAA Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors (2011) (48)
Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of α1‐subunit‐deficient mice (2006) (47)
GABA(A) receptor alpha1, alpha4, and beta3 subunit mRNA and protein expression in the frontal cortex of human alcoholics. (1998) (47)
The parvalbumin-positive interneurons in the mouse dentate gyrus express GABAA receptor subunits alpha1, beta2, and delta along their extrasynaptic cell membrane (2013) (46)
Novel positive allosteric modulators of GABAA receptors: Do subtle differences in activity at α1 plus α5 versus α2 plus α3 subunits account for dissimilarities in behavioral effects in rats? (2010) (46)
gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties. (1994) (46)
Subtype selectivity of α+β− site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors (2013) (46)
Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β− interface (2013) (45)
Properties of a high affinity binding site for [3H]avermectin B1a. (1984) (45)
The point mutation gamma 2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes. (2010) (45)
Synthesis, in vitro affinity, and efficacy of a bis 8-ethynyl-4H-imidazo[1,5a]- [1,4]benzodiazepine analogue, the first bivalent alpha5 subtype selective BzR/GABA(A) antagonist. (2003) (45)
Isolation of type I and type II GABAA‐benzodiazepine receptors by immunoaffinity chromatography (1991) (45)
Pharmacological properties of GABAA receptors containing gamma1 subunits. (2006) (44)
Antibodies specific for GABAA receptor alpha subunits reveal that chronic alcohol treatment down-regulates alpha-subunit expression in rat brain regions. (1993) (44)
Comparison of benzodiazepine receptor binding in membranes from human or rat brain (1985) (43)
Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor γ2 F77I point mutation (2005) (43)
Plasticity of GABAA Receptors after Ethanol Pre-Exposure in Cultured Hippocampal Neurons (2011) (41)
Aberrant GABAA Receptor Expression in the Dentate Gyrus of the Epileptic Mutant Mouse Stargazer (2006) (40)
Neurotoxins from Snake Venoms and α-Conotoxin ImI Inhibit Functionally Active Ionotropic γ-Aminobutyric Acid (GABA) Receptors* (2015) (40)
Endogenous [3H]flunitrazepam binding in human embryonic kidney cell line 293. (1995) (40)
Biological evaluation of 2'-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET. (2004) (40)
Potassium-evoked release of taurine from synaptosomal fractions of rat cerebral cortex (1976) (40)
Polyclonal Antibodies Directed Against an Epitope Specific for the α4‐Subunit of GABAA Receptors Identify a 67‐kDa Protein in Rat Brain Membranes (1994) (40)
Detection and Binding Properties of GABAA Receptor Assembly Intermediates* (2001) (40)
Increased expression of GABA(A) receptor beta-subunits in the hippocampus of patients with temporal lobe epilepsy. (2003) (40)
The Cell Adhesion Molecule Neuroplastin-65 Is a Novel Interaction Partner of γ-Aminobutyric Acid Type A Receptors* (2012) (39)
Assembly of GABAA receptors (Review) (2008) (39)
Behavioral effects of tryptophan depletion in seasonal affective disorder associated with the serotonin transporter gene? (1999) (38)
Regulation of GABAA Receptor Dynamics by Interaction with Purinergic P2X2 Receptors* (2011) (37)
γ-Aminobutyric Acid Receptor (GABAA) Subunits in Rat Nucleus Tractus Solitarii (NTS) Revealed by Polymerase Chain Reaction (PCR) and Immunohistochemistry (2001) (36)
GABAA receptor subunits in the human amygdala and hippocampus: Immunohistochemical distribution of 7 subunits (2018) (36)
Molecular basis of pharmacological heterogeneity of GABAA receptors. (1992) (34)
Gel-based mass spectrometric analysis of recombinant GABA(A) receptor subunits representing strongly hydrophobic transmembrane proteins. (2008) (34)
Development of γ‐aminobutyric acidergic synapses in cultured hippocampal neurons (2006) (33)
Postnatal development of proteins irreversibly labeled by [3H]flunitrazepam (1982) (33)
In vivo and in vitro evaluation of [18F]FETO with respect to the adrenocortical and GABAergic system in rats (2003) (33)
Development of gamma-aminobutyric acidergic synapses in cultured hippocampal neurons. (2006) (32)
Initially expressed early rat embryonic GABAA receptor Cl– ion channels exhibit heterogeneous channel properties (1998) (32)
Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability. (2018) (32)
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. (2008) (31)
UPTAKE OF TAURINE INTO SUBCELLULAR FRACTIONS OF C‐6 GLIOMA CELLS 1 (1976) (31)
Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain. (1979) (31)
Homologous sites of GABAA receptor α1, β3 and γ2 subunits are important for assembly (2002) (31)
Binding of γ‐Aminobutyric AcidA Receptors to Tubulin (1994) (30)
Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption. (2002) (29)
Schizophrenia and the dopamine‐β‐hydroxylase gene: results of a linkage and association study (1996) (29)
Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor. (1984) (29)
N‐Deglycosylation and immunological identification indicates the existence of β‐subunit isoforms of the rat GABAA receptor (1991) (29)
Localization of GABA‐A receptor alpha subunits on neurochemically distinct cell types in the rat locus coeruleus (2011) (29)
Interaction between serotonin 5-HT2A receptor gene and dopamine transporter (DAT1) gene polymorphisms influences personality trait of persistence in Austrian Caucasians (2010) (29)
Neuronal localization of specific brain phosphoproteins (1978) (29)
Association Studies of Candidate Genes in Bipolar Disorders (2000) (28)
Subunit Compensation and Plasticity of Synaptic GABAA Receptors Induced by Ethanol in α4 Subunit Knockout Mice (2011) (28)
Phosphorylation of a single mast cell protein in response to drugs that inhibit secretion. (1981) (28)
Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model (2004) (28)
Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: blood levels, EEG mapping and safety evaluation. (1993) (28)
Comparison of Benzodiazepine Receptors in Cerebellum and Inferior Colliculus (1986) (27)
New insights on the role of gephyrin in regulating both phasic and tonic GABAergic inhibition in rat hippocampal neurons in culture (2009) (27)
Differential localization of GABAA receptor subunits in relation to rat striatopallidal and pallidopallidal synapses (2011) (27)
First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. (2016) (26)
Unraveling the function of GABA(A) receptor subtypes. (2000) (26)
Identification of α 1-, α 2- and α 3-subunit isoforms of the GABAA-benzodiazepine receptor in the rat brain (1991) (25)
Identification of an amino acid sequence within GABAA receptor β3 subunits that is important for receptor assembly (2002) (25)
Role of the GABAA receptor γ2 subunit in the development of gonadotropin‐releasing hormone neurons in vivo (2000) (25)
GABAA α6-Containing Receptors Are Selectively Compromised in Cerebellar Granule Cells of the Ataxic Mouse, Stargazer* (2007) (25)
Allosteric modulation of [3H]flunitrazepam binding to recombinant GABAA receptors. (1995) (25)
Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABAA receptors (2019) (24)
No association of the neuropeptide Y (Leu7Pro) and ghrelin gene (Arg51Gln, Leu72Met, Gln90Leu) single nucleotide polymorphisms with eating disorders (2011) (24)
Transient transfection coupled to baculovirus infection for rapid protein expression screening in insect cells. (2012) (24)
Light treatment in depressive illness. Polysomnographic, psychometric and neuroendocrinological findings. (1986) (23)
Benzodiazepine-mediated regulation of alpha1, alpha2, beta1-3 and gamma2 GABA(A) receptor subunit proteins in the rat brain hippocampus and cortex. (1999) (23)
Comparative Bioavailability Studies with a New Mixed-micelles Solution of Diazepam Utilizing Radioreceptor Assay, Psychometry and EEG Brain Mapping (1988) (23)
Extensive Heterogeneity of Recombinant γ-Aminobutyric AcidA Receptors Expressed in α4β3γ2-Transfected Human Embryonic Kidney 293 Cells (1996) (23)
GABA(A) receptor assembly. Identification and structure of gamma(2) sequences forming the intersubunit contacts with alpha(1) and beta(3) subunits. (2000) (23)
Cerebellar α6‐subunit‐containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders (2018) (22)
Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase. (2009) (22)
Potency of several type I-benzodiazepine receptor ligands for inhibition of [3H]flunitrazepam binding in different rat brain tissues. (1991) (22)
[3H]clonazepam, like [3H]flunitrazepam, is a photoaffinity label for the central type of benzodiazepine receptors. (1982) (21)
Removal of GABAA Receptor γ2 Subunits from Parvalbumin Neurons Causes Wide-Ranging Behavioral Alterations (2011) (21)
Identification of subunits mediating clustering of GABAA receptors by rapsyn (1999) (21)
Sedimentation characteristics of subcellular vesicles derived from three glial systems (1978) (21)
Differential Degradation of Different Benzodiazepine Binding Proteins by Incubation of Membranes from Cerebellum or Hippocampus with Trypsin (1985) (20)
N-Substituted 4-amino-3,3-dipropyl-2(3H)-furanones: new positive allosteric modulators of the GABA(A) receptor sharing electrophysiological properties with the anticonvulsant loreclezole. (2002) (20)
Possible linkage of schizophrenia and bipolar affective disorder to chromosome 3q29; a follow-up. (2004) (20)
Long-range interactions in neuronal gene expression: evidence from gene targeting in the GABA(A) receptor beta2-alpha6-alpha1-gamma2 subunit gene cluster. (2000) (20)
Histaminergic pharmacology of homo-oligomeric β3 γ-aminobutyric acid type A receptors characterized by surface plasmon resonance biosensor technology. (2012) (20)
Synthesis and GABAA receptor activity of 6-oxa-analogs of neurosteroids (2000) (19)
Estimating the efficiency of benzodiazepines on GABAA receptors comprising γ1 or γ2 subunits (2008) (19)
Structural and Functional Remodeling of Amygdala GABAergic Synapses in Associative Fear Learning (2019) (19)
Improved radioimmunoassay of melatonin in serum. (1987) (19)
The α6 subunit-containing GABAA receptor: A novel drug target for inhibition of trigeminal activation (2018) (19)
A Novel Site on γ3 Subunits Important for Assembly of GABAA Receptors* (2002) (19)
The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development (2016) (18)
Removal of GABA ( A ) Receptor gamma 2 Subunits from Parvalbumin Neurons Causes Wide-Ranging Behavioral Alterations (18)
Glutamate‐Stimulated Phosphorylation of a Specific Protein in P2 Fractions of Rat Cerebral Cortex (1981) (18)
Binge Drinking: In Search of its Molecular Target via the GABAA Receptor (2011) (18)
[35S]tert.-butylbicyclophosphorothionate and avermectin bind to different sites associated with the γ-aminobutyric acid-benzodiazepine receptor complex (1984) (17)
Association study of schizophrenia spectrum disorders and dopamine D3 receptor gene: is schizoaffective disorder special? (2000) (17)
65-13 Association of GABAA receptor subunit genes with childhood absence epilepsy (1997) (17)
Evidence for the Existence of Differential O‐Glycosylated α5‐Subunits of the γ‐Aminobutyric AcidA Receptor in the Rat Brain (1993) (17)
Somatostatin-induced phosphorylation of mast cell proteins. (1981) (16)
Identification of amino acid residues important for assembly of GABAA receptor α1 and γ2 subunits (2006) (16)
Sedimentation and release properties of glial particles present in P2-fractions isolated from rat cerebral cortex (1979) (15)
Subunit Composition and Pharmacological Characterization ofγ -Aminobutyric Acid Type A Receptors in Frog Pituitary Melanotrophs. (2000) (15)
5-[1'-(2'-N-Arylsulfonyl-1',2',3',4'-tetrahydroisoquinolyl)]-4, 5-dihydro-2(3H)-furanones: positive allosteric modulators of the GABA(A) receptor with a new mode of action. (2000) (15)
Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice (2016) (15)
Immunohistochemical distribution of 10 GABAA receptor subunits in the forebrain of the rhesus monkey Macaca mulatta (2020) (15)
Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain (2012) (15)
AMPA and kainate receptors mediate mutually exclusive effects on GABAA receptor expression in cultured mouse cerebellar granule neurones (2007) (14)
Heterogeneity of GABAA-benzodiazepine receptors. (1991) (14)
Homologous sites of GABA(A) receptor alpha(1), beta(3) and gamma(2) subunits are important for assembly. (2002) (14)
Photoaffinity Labeling of Different Benzodiazepine Receptors at Physiological Temperature (1984) (14)
Extensive heterogeneity of recombinant gamma-aminobutyric acidA receptors expressed in alpha 4 beta 3 gamma 2-transfected human embryonic kidney 293 cells. (1996) (14)
Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β− Site (2014) (13)
Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: The approximated activation of receptor subtypes may explain behavioral effects (2014) (13)
Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys (2018) (13)
Early postnatal switch in GABAA receptor α-subunits in the reticular thalamic nucleus. (2016) (13)
Benzodiazepine receptors: Multiple receptors or multiple conformations? (2005) (13)
A Novel Serine Kinase with Specificity for β3-Subunits Is Tightly Associated with GABAA Receptors* (1999) (13)
Immunohistochemical localization of the alpha 1, alpha 2 and alpha 3 subunit of the GABAA receptor in the rat brain. (1991) (13)
Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomes. (2013) (13)
Neurosteroid analogue photolabeling of a site in the TM 3 domain of the β 3 subunit of the GABAA receptor (2012) (13)
17 β-estradiol modulates GABAergic synaptic transmission and tonic currents during development in vitro (2007) (12)
Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABAA receptors (2013) (12)
Immunohistochemical and neurochemical evidence for GABAA receptor heterogeneity between the hypothalamus and cortex (1994) (12)
Clustering of Extrasynaptic GABA A Receptors Modulates Tonic Inhibition in Cultured Hippocampal Neurons* (2004) (12)
Properties of benzodiazepine receptors in rat retina. (1982) (12)
Comparison of Tryptic Peptides of Benzodiazepine Binding Proteins Photolabeled with [3H]Flunitrazepam or [3H]Ro 15–4513 (1987) (12)
Pharmaco‐EEG, behavioural methods and blood levels in the comparison of temazepam and flunitrazepam (1986) (12)
Subunit Composition and Structure of GABAA-Receptor Subtypes (2007) (12)
Additional support for linkage of schizophrenia and bipolar disorder to chromosome 3q29 (2007) (11)
Mutagenesis and computational docking studies support the existence of a histamine binding site at the extracellular β3+β3− interface of homooligomeric β3 GABAA receptors (2016) (11)
A novel site on gamma 3 subunits important for assembly of GABA(A) receptors. (2002) (11)
Use of bicuculline, a GABA antagonist, as a template for the development of a new class of ligands showing positive allosteric modulation of the GABA(A) receptor. (2000) (11)
Pharmacology of benzodiazepine receptors: an update. (1992) (11)
Binding of gamma-aminobutyric acidA receptors to tubulin. (1994) (10)
Comparison of two different benzodiazepine binding proteins by peptide mapping after limited proteolysis (1988) (10)
HETEROGENEITY OF GABAA RECEPTORS (1992) (10)
Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits. (2006) (10)
Subcellular distribution of dopamine-sensitive adenylate cyclase (1976) (10)
[Orally-administered taurine in therapy-resistant epilepsy (author's transl)]. (1977) (9)
GABAA receptors as targets for different classes of drugs (2006) (9)
α6-Containing GABAA Receptors: Functional Roles and Therapeutic Potentials (2022) (9)
Spontaneous Cross-link of Mutated α1 Subunits during GABAA Receptor Assembly* (2007) (9)
α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia (2020) (9)
BENZODIAZEPINE-MEDIATED REGULATION OF a 1 , a 2 , b 1 – 3 AND g 2 GABAA RECEPTOR SUBUNIT PROTEINS IN THE RAT BRAIN HIPPOCAMPUS AND CORTEX (1999) (9)
Separation of alpha 1, alpha 2 and alpha 3 subunits of the GABAA-benzodiazepine receptor complex by immunoaffinity chromatography. (1991) (8)
Biochemical, immunological, and pharmacological characterization of GABAA-benzodiazepine receptor subtypes. (1992) (8)
Association of proteins irreversibly labeled by 3H-flunitrazepam with different benzodiazepine. (1983) (8)
Nocturnal Traffic Noise, Sleep, and Quality of Awakening: Neurophysiologic, Psychometric, and Receptor Activity Changes after Quazepam (1985) (8)
A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis. (2008) (8)
INTERACTIONS OF ANXIOLYTIC DRUGS WITH BENZODIAZEPINE RECEPTORS (1981) (8)
Alterations in GABAA Receptor Subunit Expression in the Amygdala and Entorhinal Cortex in Human Temporal Lobe Epilepsy. (2019) (8)
Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits. (1996) (8)
Differential cross talk of ROD compounds with the benzodiazepine binding site. (2001) (8)
Distribution of GABAAreceptor alpha 1 subunit‐like immunoreactivity in comparision with that of enkephalin and substance P in the rat forebrain (1995) (7)
Spontaneous cross-link of mutated alpha1 subunits during GABA(A) receptor assembly. (2007) (7)
Evidence for the existence of several different alpha- and beta-subunits of the GABA/benzodiazepine receptor complex from rat brain. (1989) (7)
Evidence for the existence of differential O-glycosylated alpha 5-subunits of the gamma-aminobutyric acidA receptor in the rat brain. (1993) (7)
Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABAA Receptors. (2018) (6)
Pharmacological Properties of GABA A Receptors Containing 1 Subunits □ S (2006) (6)
Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits. (2008) (6)
A Significant Part of Native g -Aminobutyric Acid A Receptors Containing a 4 Subunits Do Not Contain g or d Subunits* (1999) (6)
Unravelling the role of GABAA receptor subtypes in distinct neurons and behaviour (2012) (5)
GABA , Receptor al , a 4 , and p 3 Subunit mRNA and Protein Expression in the Frontal Cortex of Human Alcoholics (2006) (5)
No proof of linkage between schizophrenia-related disorders including schizophrenia and chromosome 2q21 region (2005) (5)
GABA receptor associated drug receptors. (1981) (5)
GABA(A) receptor subtype-selectivity of novel bicuculline derivatives. (2015) (5)
Insights into functional pharmacology of α1 GABAA receptors: how much does partial activation at the benzodiazepine site matter? (2013) (5)
Identification of alpha 1-, alpha 2- and alpha 3-subunit isoforms of the GABAA-benzodiazepine receptor in the rat brain. (1991) (5)
Targeting α6GABAA receptors as a novel therapy for schizophrenia: A proof-of-concept preclinical study using various animal models. (2022) (4)
Properties of [3H]taurine release from crude synaptosomal fractions of rat cerebral cortex (1979) (4)
Modification of the apparent molecular weight of different benzodiazepine binding proteins from rat brain membranes by various endoglycosidases (1988) (4)
Interaction of benzodiazepine agonists and antagonists with different benzodiazepine receptors. (1983) (4)
The point mutation γ 2 F 77 I changes the potency and ef fi cacy of benzodiazepine site ligands in different GABAA receptor subtypes (2010) (3)
Benzodiazepine receptor subtypes and their possible clinical significance. (1989) (3)
GABAA receptors in GtoPdb v.2021.3. (2021) (3)
RFLP linkage study in schizophrenia on chromosome 2 (1992) (3)
Subunit composition and pharmacological characterization of gamma-aminobutyric acid type A receptors in frog pituitary melanotrophs. (2000) (3)
European multicentre evaluation of the analytical performance of the Abbott AxSYM Abused Drugs Assays. (1997) (3)
Normal personality traits related to neurotransmitter receptor genes (1996) (3)
GABAA receptor subtypes: structural variety raises hope for new therapy concepts (2015) (3)
347. The role of the serotinin transporter gene on the behavioral effects of tryptophan depletion in patients with seasonal affective disorder (1998) (3)
Use of Bicuculline, a GABA Antagonist, as a Template for the Development of a New Class of Ligands Showing Positive Allosteric Modulation of the GABAA Receptor. (2001) (3)
On the Value of CNS, ANS and Behavioral Measures in Early Clinical Psychopharmacology (1985) (2)
The influence of phenotype on the outcome of linkage analysis of schizophrenia (1996) (2)
Neurotoxins from Snake Venoms and α-Conotoxin ImI Inhibit Functionally Active Ionotropic GABA Receptors* (2015) (2)
REGULATION OF-AMINOBUTYRIC ACID A ( GABA A ) RECEPTOR DYNAMICS BY INTERACTION WITH PURINERGIC P 2 X 2 RECEPTORS (2011) (2)
6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors. (2008) (2)
Development of GABAergic Synapses in Cultured Hippocampal Neurons (2011) (2)
Ca 2 + and cyclic AMP regulate phosphorylation of same two membrane-associated proteins specific to nerve tissue ( protein kinase / protein phosphorylation / synaptic membranes / synaptosomes ) (2)
Advances in Pharmacology (2006) (2)
Novelty seeking and harm avoidance and dopamine 4 and serotonine 2A receptor gene polymorphisms (2000) (2)
[3H]propyl-6-azido-beta-carboline-3-carboxylate: a new photoaffinity label for the GABAA-benzodiazepine receptor. (1995) (2)
[GABA(A) benzodiazepine receptors and epilepsy]. (1990) (2)
GABAA receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (2)
subunit of the GABAA receptor (2012) (1)
Corrigendum to “Histaminergic pharmacology of homo-oligomeric β3 γ-aminobutyric acid type A receptors characterized by surface plasmon resonance biosensor technology” [Biochem. Pharmacol. 84 (2012) 341–351] (2012) (1)
Mutation screen of the GABAA receptor beta3 subunit gene in patients with childhood absence epilepsy (2004) (1)
Anxioselective anxiolytics: additional perspective. (2013) (1)
Residual effects of zolpidem on GABAA receptor-mediated mIPSCs of hippocampal neurons in F77I gamma2 subunit point mutant mice. (2004) (1)
Fear learning triggers structural changes at GABAergic synapses in the basal amygdala (2010) (1)
Sedimentation and release properties of P2 fractions derived from rat cerebral cortex slices incubated with radiolabeled GABA for a short or long time period (1981) (1)
Proteomic Study of Hydrophobic (Membrane) Proteins and Hydrophobic Protein Complexes (2008) (1)
370. Dopamine transporter (DAT 1) genotypes and [123I]-β-CIT SPECT imaging of DAT in Tourette Disorder (TD) (2000) (1)
Apparent identity ofα-subunit of pyruvate dehydrogenase and the protein phosphorylated in the presence of glutamate in P2-fractions of rat cerebral cortex (2005) (1)
Positive modulation of cerebellar α6GABAA receptors for treating essential tremor: a proof-of-concept study in harmaline-treated mice (2021) (1)
Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice (2016) (1)
8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABAA Receptor (2021) (1)
Binding of Various Benzodiazepine Receptor Ligands to Different Benzodiazepine Receptor Subtypes (1985) (1)
Benzodiazepines modulate GABAA receptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity (2009) (0)
Fornai DIFFERENTIAL LOCALIZATION OF GABAA RECEPTOR SUBUNITS IN RELATION TO RAT STRIATO-PALLIDAL AND PALLIDO-PALLIDAL SYNAPSES (2012) (0)
α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia (2020) (0)
Drug interactions with cyclic nucleotide and protein phosphorylation systems. (1979) (0)
NeuronsCurrents in Rat Suprachiasmatic Zinc and Flunitrazepam Modulation of (2015) (0)
17beta-estradiol alters tonic and phasic GABAergic currents during development in vitro (2007) (0)
14-83 Blunted response to the citalopram challenge test in patients with opioid dependence (1997) (0)
SEVERAL NEW BEN~IAZEPINES SELECFlVEL¥ IN~ILACT WITH A BENZODIAZEPINE ~OR SUBTYPE (1983) (0)
Linkage and association study of schizophrenia and DNA-markers on chromosome 9q (1995) (0)
39-52 Two-trait-locus linkage analysis: An application to schizophrenia (1997) (0)
P.1.149 Neuroendocrine responses to the citalopram challenge test in major depression (1997) (0)
Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β− Site (2013) (0)
Understanding subtype-selective allosteric modulation of GABAAreceptors (2012) (0)
Dopamine D2, D3 and serotonin 2A receptor genes in schizophrenia: results of an association study (1996) (0)
Identification of alpha 2- and alpha 3-subunits of the GABAA-benzodiazepine receptor complex purified from the brains of young rats. (1990) (0)
Cerebellar α6GABAA Receptors as a Therapeutic Target for Essential Tremor: Proof-of-Concept Study with Ethanol and Pyrazoloquinolinones (2023) (0)
Fear learning induces structural and functional plasticity at GABAergic synapses in the basolateral amygdala (2011) (0)
Pharmacological Properties of GABA A Receptors Containing (cid:1) 1 Subunits □ S (2006) (0)
Comparing the high affinity benzodiazepine binding site with the homologous “CGS 9895” site in GABA‐A receptors (1059.1) (2014) (0)
Author Index and Subject Index (2000) (0)
RELP-LINKAGE STUDIES OF SCHIZOPHRENIA ON CHROMOSOME 2 (1991) (0)
Engineering GABAA receptors to modulate the activity of selected types of neurons (2004) (0)
Establishing a new mouse model for investigating the function of amygdala neurons in anxiety (2008) (0)
Insights into functional pharmacology of α1 GABAA receptors: how much does partial activation at the benzodiazepine site matter? (2013) (0)
Subject Index Vol. 25, Suppl 2, 1986 (1986) (0)
Heterogeneity of GABA ,-benzodiazepine receptors (2009) (0)
Normal CAG repeats in the Huntington gene in a family with benign familial chorea. (1996) (0)
Localization of a functional GABA-A receptor in the guinea pig myenteric plexus (2003) (0)
Characterization of the binding site between the GABAA receptor3 subunit and gephyrin (2010) (0)
Subject Index Vol. 42, 2000 (2000) (0)
P-11-28 Blunted response in the citalopram challenge test (CCT) in diabetes (1995) (0)
49-1 Dopamine and serotonin receptor genotypes and therpeutic response to neuroleptics in schizophrenia (1997) (0)
Understanding subtype-selective allosteric modulation of GABAA receptors (2012) (0)
Search for alpha 3 beta 2/3 gamma 2 subtype selective ligands that are stable on human liver microsomes (2012) (0)
Flumazenil Failed to Rapidly Terminate Midazolam Anesthesia in an Opiate Addict (1991) (0)
P.1.057 Neuroendocrine challenge of serotonergic function with citalopram in healthy volunteers (1996) (0)
Schizophrenia linkage studies on chromosome 2q (1993) (0)
P.1.135 Neuroendocrine challenge with citalopram in healthy volunteers (1997) (0)
The cerebellar α6 subunit-containing GABA A receptor: A novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders (2018) (0)
P.1.056 Blunted reaction to the citalopram challenge test in patients with major depression (1996) (0)
Identification of amino acid residues important for assembly of GABAA receptor a 1 and c 2 subunits (2006) (0)
501. Neuroendocrine responses to the citalopram challenge test in depression (1996) (0)
Using Multiple Approaches in Docking Pose Evaluation – Application to the GABAA Receptor (2009) (0)
A Novel Target for Migraine Therapy: the α6 Subunit-Containing GABA A Receptor (2018) (0)
EDPC: a novel high affinity ligand for the benzodiazepine site on rat GABAA receptors (1999) (0)
Meet Our Editorial Board Member (2018) (0)
Molecular Heterogeneity of GABAA-Benzodiazepine Receptors (1989) (0)
P-2-27 The Citalopram Challenge Test (CCT) as a probe for serotonergic function in depression (1995) (0)
SCHIZOPHRENIA FAMILY STUDY:MOLECULARGENETICS, PERSONALITIES (1992) (0)
A Novel Drug Target for Migraine: The GABAA Receptor α6 Subtype in Trigeminal Ganglia (2019) (0)
Apparent identity of alpha-subunit of pyruvate dehydrogenase and the protein phosphorylated in the presence of glutamate in P2-fractions of rat cerebral cortex. (1984) (0)
Contents Vol. 42, 2000 (2000) (0)
N-substituted 1- (butyrolactone) -isochinoline for the treatment of nerve disorders (2000) (0)
Proposal of a new GABAA-benzodiazepine receptor nomenclature based on the subunit composition of GABAA receptors (1991) (0)
INTERACTION OF GABAA RECEPTORS WITH PURINERGIC P2X2 RECEPTORS (2010) (0)

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