Wiebke Arlt

Q: What Schools Are Affiliated With Wiebke Arlt

Wiebke Arlt is affiliated with the following schools: University of Freiburg, University of Cologne, University of Birmingham, University of California, San Francisco, University of Würzburg, University of Manchester

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Wiebke Arlt

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#5736

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#8625

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#2959

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#4044

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Philosophy

Wiebke Arlt's Degrees

PhD Endocrinology University of Cologne
Doctorate Medicine University of Cologne

Why Is Wiebke Arlt Influential?

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According to Wikipedia, Wiebke Arlt is a German endocrinologist and William Withering Chair of Medicine at the University of Birmingham. She specialises in adrenal disease and disorders of sex development. Career Arlt studied medicine at the University of Cologne, completing a MBChB in 1990 and an academic MD in 1993. She trained in endocrinology at Universitätsklinikum Würzburg and finished her training in 1998. She then embarked on a research career, beginning in the University of California in San Francisco under the supervision of pediatric endocrinologist Walter L. Miller, with a fellowship grant from the German Research Council. She returned to Würzburg as a consultant endocrinologist briefly in 2001, before moving to the University of Birmingham in England in 2002 with another fellowship from the German Research Council. She became a senior lecturer at the university in 2004, the same year that she received a Medical Research Council clinical fellowship. She was promoted to Head of the Centre for Endocrinology, Diabetes and Metabolism in 2008 and William Withering Chair of Medicine in 2014. She is also director of Birmingham's Institute of Metabolism and Systems Research , and is an honorary consultant endocrinologist at the Queen Elizabeth Hospital Birmingham, where she specialises in adrenal and gonadal disease.

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Wiebke Arlt's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline. (2016) (987)
Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. (2016) (982)
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine (2008) (807)
Dehydroepiandrosterone replacement in women with adrenal insufficiency. (1999) (611)
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome (2004) (457)
Congenital adrenal hyperplasia (1966) (396)
Health Status of Adults with Congenital Adrenal Hyperplasia: A Cohort Study of 203 Patients (2010) (388)
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study (2004) (337)
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS) (2010) (333)
Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency (2003) (311)
Urine Steroid Metabolomics as a Biomarker Tool for Detecting Malignancy in Adrenal Tumors (2011) (307)
Consensus statement on the diagnosis, treatment and follow‐up of patients with primary adrenal insufficiency (2014) (307)
Combination chemotherapy in advanced adrenocortical carcinoma. (2012) (275)
The Regulation of Steroid Action by Sulfation and Desulfation (2015) (275)
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017 (2018) (253)
TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood. (2010) (251)
Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis. (2007) (250)
Diagnosis and management of adrenal insufficiency. (2015) (247)
Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline. (2014) (239)
Hyperandrogenemia Predicts Metabolic Phenotype in Polycystic Ovary Syndrome: The Utility of Serum Androstenedione (2014) (237)
Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer. (2012) (235)
Modified-release hydrocortisone to provide circadian cortisol profiles. (2009) (226)
Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D. (2002) (201)
Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. (1998) (199)
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100. (2012) (187)
Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis (2014) (178)
Society for Endocrinology UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development (Revised 2015) (2015) (178)
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism (2017) (176)
The approach to the adult with newly diagnosed adrenal insufficiency. (2009) (162)
Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5. (2004) (161)
Adrenal corticosteroid biosynthesis, metabolism, and action. (2005) (160)
Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature (2007) (159)
Genetics of congenital adrenal hyperplasia. (2009) (158)
11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome (2016) (157)
DHEA treatment: myth or reality? (2002) (154)
Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline. (2018) (153)
Adrenal insufficiency. (2003) (152)
Inactivating PAPSS2 mutations in a patient with premature pubarche. (2009) (151)
Dehydroepiandrosterone as a regulator of immune cell function (2010) (150)
UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development (2011) (149)
Thiazolidinediones but Not Metformin Directly Inhibit the Steroidogenic Enzymes P450c17 and 3β-Hydroxysteroid Dehydrogenase* (2001) (148)
Dehydroepiandrosterone supplementation in healthy men with an age-related decline of dehydroepiandrosterone secretion. (2001) (145)
Quality of glucocorticoid replacement in adrenal insufficiency: clinical assessment vs. timed serum cortisol measurements (2006) (145)
Biotransformation of oral dehydroepiandrosterone in elderly men: significant increase in circulating estrogens. (1999) (144)
Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome. (2003) (141)
Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review (2019) (141)
Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency. (2009) (138)
Adrenal crisis in treated Addison's disease: a predictable but under-managed event. (2010) (135)
Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years. (2012) (134)
Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement. (2013) (130)
Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. (2017) (128)
Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase (2016) (127)
MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis (2016) (122)
Pheochromocytoma Is Characterized by Catecholamine-Mediated Myocarditis, Focal and Diffuse Myocardial Fibrosis, and Myocardial Dysfunction. (2016) (121)
Premature adrenarche: novel lessons from early onset androgen excess. (2011) (119)
Dehydroepiandrosterone and ageing. (2004) (112)
Congenital adrenal hyperplasia and P450 oxidoreductase deficiency (2007) (111)
Genotype-Phenotype Analysis in Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency (2011) (109)
Intracrine androgen biosynthesis, metabolism and action revisited (2017) (109)
A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia. (2015) (108)
Deletion of the adrenocorticotropin receptor gene in human adrenocortical tumors: implications for tumorigenesis. (1997) (107)
AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome (2017) (106)
Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database (2018) (105)
Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) (2017) (104)
Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome. (2009) (104)
Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. (2002) (103)
Health Problems in Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency (2011) (103)
A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids (2017) (101)
Dehydroepiandrosterone replacement in women with adrenal insufficiency: effects on body composition, serum leptin, bone turnover, and exercise capacity. (2001) (101)
Androgen therapy in women. (2006) (101)
Approach to the patient: the adult with congenital adrenal hyperplasia. (2013) (100)
Changes Over Time in Sex Assignment for Disorders of Sex Development (2014) (100)
Gorham‐Stout Disease—Stabilization During Bisphosphonate Treatment (2004) (100)
THERAPY OF ENDOCRINE DISEASE: Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing's syndrome: a systematic review and meta-analysis. (2016) (97)
Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol (2015) (96)
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatographytandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma (2013) (95)
A pharmacokinetic and pharmacodynamic study of delayed‐ and extended‐release hydrocortisone (ChronocortTM) vs. conventional hydrocortisone (CortefTM) in the treatment of congenital adrenal hyperplasia (2010) (95)
OX40 Ligand and CD30 Ligand Are Expressed on Adult but Not Neonatal CD4+CD3− Inducer Cells: Evidence That IL-7 Signals Regulate CD30 Ligand but Not OX40 Ligand Expression1 (2005) (92)
Genotype-Phenotype Correlation in 153 Adult Patients With Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency: Analysis of the United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE) Cohort (2012) (92)
Hormones and immune function: implications of aging (2004) (92)
Prenatal diagnosis of P450 oxidoreductase deficiency (ORD): A disorder causing low pregnancy estriol, maternal and fetal virilization, and the Antley–Bixler syndrome phenotype (2004) (90)
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency. (2008) (89)
An oral multiparticulate, modified‐release, hydrocortisone replacement therapy that provides physiological cortisol exposure (2014) (88)
Congenital adrenal hyperplasia - current insights in pathophysiology, diagnostics and management. (2021) (88)
The cortisol stress response induced by surgery: A systematic review and meta‐analysis (2018) (88)
Dhea Replacement in Women with Adrenal Insufficiency—Pharmacokinetics, Bioconversion and Clinical Effects on Well-Being, Sexuality and Cognition (2000) (88)
Novel Associations in Disorders of Sex Development: Findings From the I-DSD Registry (2013) (87)
Octreotide LAR® treatment throughout pregnancy in an acromegalic woman (2001) (86)
Adrenal insufficiency (2003) (84)
No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: in vivo and in vitro studies. (2005) (84)
MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease (2017) (83)
Functional consequences of seven novel mutations in the CYP11B1 gene: four mutations associated with nonclassic and three mutations causing classic 11{beta}-hydroxylase deficiency. (2010) (83)
Treatment and health outcomes in adults with congenital adrenal hyperplasia (2014) (82)
A Missense Mutation in the Human Cytochrome b5 Gene causes 46,XY Disorder of Sex Development due to True Isolated 17,20 Lyase Deficiency (2011) (82)
Biochemical diagnosis of Antley–Bixler syndrome by steroid analysis (2004) (81)
Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma. (2015) (81)
DIAGNOSIS OF ENDOCRINE DISEASE: The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis. (2016) (80)
CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma (2018) (80)
Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study (2020) (79)
Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock. (2006) (78)
Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality (2017) (78)
Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P. (2007) (77)
Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone. (2016) (77)
A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics (2019) (75)
What is the best diagnostic and therapeutic management strategy for an Addison patient during pregnancy? (2013) (72)
Impairment of adrenocortical function associated with increased plasma tumor necrosis factor-alpha and interleukin-6 concentrations in African trypanosomiasis. (1994) (72)
Mapping the proteo-genomic convergence of human diseases (2021) (72)
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of adrenal insufficiency (2020) (70)
Expression of adrenocorticotrophic hormone receptor mRNA in human adrenocortical neoplasms: correlation with P450scc expression (1997) (70)
Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM). (2017) (69)
PAPSS2 Deficiency Causes Androgen Excess via Impaired DHEA Sulfation—In Vitro and in Vivo Studies in a Family Harboring Two Novel PAPSS2 Mutations (2015) (69)
Dehydroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation. (2010) (69)
Cortisol, DHEA sulphate, their ratio, and all-cause and cause-specific mortality in the Vietnam Experience Study. (2010) (68)
Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess (2019) (65)
Epidemiology of adrenal tumours in Olmsted County, Minnesota, USA: a population-based cohort study. (2020) (65)
Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency (2010) (64)
Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers (2017) (64)
Adult Consequences of Congenital Adrenal Hyperplasia (2007) (64)
The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer (2016) (63)
SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients (2016) (63)
Guidelines for the management of glucocorticoids during the peri‐operative period for patients with adrenal insufficiency (2020) (62)
Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women (2015) (60)
Mutation of proline 409 to arginine in the meander region of cytochrome p450c17 causes severe 17 alpha-hydroxylase deficiency. (2001) (58)
Management of hypoparathyroidism during pregnancy--report of twelve cases. (1998) (58)
Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism (2019) (58)
Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) (2013) (56)
Prevention of Adrenal Crisis: Cortisol Responses to Major Stress Compared to Stress Dose Hydrocortisone Delivery (2020) (56)
How to avoid precipitating an acute adrenal crisis (2012) (56)
DAX-1 expression in human adrenocortical neoplasms: implications for steroidogenesis. (1998) (55)
Clinical, Biochemical, and Radiological Characteristics of a Single-Center Retrospective Cohort of 705 Large Adrenal Tumors (2017) (54)
A diagnosis not to be missed: nonclassic steroid 11β-hydroxylase deficiency presenting with premature adrenarche and hirsutism. (2013) (53)
Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake (2013) (53)
Cortisone-reductase deficiency associated with heterozygous mutations in 11β-hydroxysteroid dehydrogenase type 1 (2011) (52)
Participation of adults with disorders/differences of sex development (DSD) in the clinical study dsd-LIFE: design, methodology, recruitment, data quality and study population (2017) (52)
Localization and expression of adrenocorticotropic hormone receptor mRNA in normal and neoplastic human adrenal cortex. (1998) (51)
Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia (2013) (51)
Increased COVID-19 infections in women with polycystic ovary syndrome: a population-based study (2021) (49)
Cortisol, DHEAS, their ratio and the metabolic syndrome: evidence from the Vietnam Experience Study. (2010) (49)
Fluconazole inhibits human adrenocortical steroidogenesis in vitro. (2012) (47)
The Journal of Steroid Biochemistry and Molecular Biology (2011) (46)
Neuroendocrine Dysfunction in African Trypanosomiasis: The Role of Cytokines a (1998) (46)
Pubertal Presentation in Seven Patients with Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency (2010) (45)
Beyond Adrenal and Ovarian Androgen Generation: Increased Peripheral 5??-reductase Activity in Women With Polycystic Ovary Syndrome (2003) (44)
Frequency and frequently overlooked: Treatment-induced endocrine dysfunction in adult long-term survivors of primary brain tumors (1997) (43)
Increased Infection Risk in Addison’s Disease and Congenital Adrenal Hyperplasia (2019) (43)
The human fetal adrenal cortex and the window of sexual differentiation (2006) (42)
Should androgen supplementation be used for poor ovarian response in IVF? (2012) (42)
Adrenocortical function in patients with macrometastases of the adrenal gland. (2000) (41)
Steroid 17alpha-hydroxylase deficiency: functional characterization of four mutations (A174E, V178D, R440C, L465P) in the CYP17A1 gene. (2009) (41)
Novel H6PDH mutations in two girls with premature adrenarche: ‘apparent’ and ‘true’ CRD can be differentiated by urinary steroid profiling (2012) (41)
Natural history of adrenal incidentalomas with and without mild autonomous cortisol excess; a systematic review and meta-analysis (2018) (41)
Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging. (2005) (40)
Relationship between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE). (2014) (40)
Prenatal Diagnosis of Congenital Adrenal Hyperplasia Caused by P450 Oxidoreductase Deficiency (2013) (39)
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease (2019) (39)
Ectopic ACTH production by a bronchial carcinoid tumour responsive to desmopressin in vivo and in vitro (1997) (38)
Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome (2016) (38)
Gonadal function in adult male patients with congenital adrenal hyperplasia. (2018) (38)
Role of ALADIN in Human Adrenocortical Cells for Oxidative Stress Response and Steroidogenesis (2015) (38)
Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment. (2014) (37)
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice (2017) (36)
Fine tuning for quality of life: 21st century approach to treatment of Addison's disease. (2009) (35)
Alternative pathway androgen biosynthesis and human fetal female virilization (2019) (35)
Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme cyp11a2. (2013) (35)
Serum testosterone, sex hormone‐binding globulin and sex‐specific risk of incident type 2 diabetes in a retrospective primary care cohort (2018) (35)
Matrix relevance LVQ in steroid metabolomics based classification of adrenal tumors (2012) (35)
Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy (2018) (35)
11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial (2019) (35)
Strategies for managing ACTH dependent mineralocorticoid excess induced by abiraterone. (2013) (34)
Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome. (2000) (34)
Guidance for the prevention and emergency management of adult patients with adrenal insufficiency. (2020) (34)
Nomenclature for alleles of the cytochrome P450 oxidoreductase gene. (2009) (34)
Causes, Patterns, and Severity of Androgen Excess in 1205 Consecutively Recruited Women (2018) (33)
The utility of ultra-high performance supercritical fluid chromatography-tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis. (2018) (33)
POR R457H is a global founder mutation causing Antley–Bixler syndrome with autosomal recessive trait (2006) (32)
Diagnosis of a malignant adrenal mass: the role of urinary steroid metabolite profiling (2017) (32)
Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty (2016) (32)
Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cells (2011) (31)
Dehydroepiandrosterone replacement therapy (2001) (30)
Urine Steroid Metabolomics as a Novel Tool for Detection of Recurrent Adrenocortical Carcinoma (2019) (30)
Monogenic Disorders of Adrenal Steroidogenesis (2018) (30)
Age-specific changes in sex steroid biosynthesis and sex development. (2007) (30)
P450 oxidoreductase deficiency and Antley–Bixler syndrome (2007) (30)
Assessment of the Safety of Glucocorticoid Regimens in Combination With Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer (2019) (30)
The Steroid Metabolome in the Isolated Ovarian Follicle and Its Response to Androgen Exposure and Antagonism (2017) (29)
Suramin in adrenocortical cancer: limited efficacy and serious toxicity (1994) (29)
DHEA: why, when, and how much--DHEA replacement in adrenal insufficiency. (2007) (29)
Influence of oral dehydroepiandrosterone (DHEA) on urinary steroid metabolites in males and females (2000) (29)
Circulating steroid hormone variations throughout different stages of prostate cancer. (2017) (29)
Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome (2015) (28)
Androgen replacement therapy in women (2005) (28)
Quantitative Brain MRI in Congenital Adrenal Hyperplasia: In Vivo Assessment of the Cognitive and Structural Impact of Steroid Hormones (2017) (28)
Significant Benefits of AIP Testing and Clinical Screening in Familial Isolated and Young-onset Pituitary Tumors (2020) (27)
Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study (2019) (27)
A novel entity of clinically isolated adrenal insufficiency caused by a partially inactivating mutation of the gene encoding for P450 side chain cleavage enzyme (CYP11A1). (2011) (26)
Concomitant Mutations in the P450 Oxidoreductase and Androgen Receptor Genes Presenting with 46,XY Disordered Sex Development and Androgenization at Adrenarche (2010) (26)
Delayed diagnosis of adrenal insufficiency in a patient with severe penoscrotal hypospadias due to two novel P450 side-change cleavage enzyme (CYP11A1) mutations (p.R360W; p.R405X) (2012) (26)
Adrenal insufficiency (2021) (26)
Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1 (2018) (26)
Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors (2022) (26)
Endocrinology in the time of COVID-19 (2020) (25)
Human fetal adrenal cells retain age‐related stem‐ and endocrine‐differentiation potential in culture (2018) (24)
Correction to: Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017 (2018) (24)
Major depressive disorder, generalised anxiety disorder, and their comorbidity: Associations with cortisol in the Vietnam Experience Study (2011) (24)
Linking Antley–Bixler syndrome and congenital adrenal hyperplasia: A novel case of P450 oxidoreductase deficiency (2006) (23)
A detour guide to the Endocrine Society Clinical Practice Guideline on case detection, diagnosis and treatment of patients with primary aldosteronism. (2010) (22)
Cushing's syndrome due to an ectopic ACTH‐secreting pituitary tumour mimicking occult paraneoplastic ectopic ACTH production (1999) (22)
Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia (2021) (22)
A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio (2012) (21)
Characterization of the molecular genetic pathology in patients with 11β‐hydroxylase deficiency (2015) (21)
Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling. (2019) (21)
Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency. (2019) (21)
Functional characterization of three CYP21A2 sequence variants (p.A265V, p.W302S, p.D322G) employing a yeast co‐expression system (2009) (20)
A Male Twin Infant with Skull Deformity and Elevated Neonatal 17–Hydroxyprogesterone: A Prismatic Case of P450 Oxidoreductase Deficiency (2004) (19)
Glucocorticoid activation by 11β‐hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross‐sectional study (2018) (19)
Bilateral Testicular Tumors Resulting in Recurrent Cushing Disease After Bilateral Adrenalectomy (2017) (18)
Mapping the Steroid Response to Major Trauma From Injury to Recovery: A Prospective Cohort Study (2019) (18)
DHEA replacement in adrenal insufficiency. (2003) (18)
Influence of 17-Hydroxyprogesterone, Progesterone and Sex Steroids on Mineralocorticoid Receptor Transactivation in Congenital Adrenal Hyperplasia (2015) (17)
Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis (2016) (17)
Age-dependent and sex-dependent disparity in mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: an international, retrospective, cohort study. (2022) (17)
SURAMIN FOR TREATMENT OF ADRENOCORTICAL CARCINOMA (1989) (16)
Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. (2014) (16)
11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension (2020) (16)
Surgery for Cushing's disease in pregnancy: our experience and a literature review. (2019) (16)
The impact of Connshing's syndrome - mild cortisol excess in primary aldosteronism drives diabetes risk. (2017) (16)
Causes, patterns and severity of androgen excess in 487 consecutively recruited pre- and post-pubertal children (2018) (15)
Update on primary bilateral macronodular adrenal hyperplasia (PBMAH) (2021) (15)
Karyotype - Phenotype Associations in Patients with Turner Syndrome. (2019) (14)
Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma (2018) (14)
Prolactinomas diagnosed in the postmenopausal period: Clinical phenotype and outcomes (2017) (14)
Implicating androgen excess in propagating metabolic disease in polycystic ovary syndrome (2020) (14)
Quality of life in Addison’s disease – the case for DHEA replacement * (2002) (14)
Cortisol, dehydroepiandrosterone sulphate, their ratio and hypertension: evidence of associations in male veterans from the Vietnam Experience Study (2011) (14)
Understanding the Role of Androgen Action in Female Adipose Tissue. (2019) (14)
Supine or sitting? Economic considerations regarding patient position during plasma metanephrine analysis for the exclusion of chromaffin tumours (2015) (14)
Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells (2016) (13)
Impact of menopause on outcomes in prolactinomas after dopamine agonist treatment withdrawal (2018) (13)
Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure. (2021) (13)
Accurate non‐invasive diagnosis and staging of non‐alcoholic fatty liver disease using the urinary steroid metabolome (2020) (12)
[Adrenal crisis. Diagnostic and therapeutic management of acute adrenal cortex insufficiency]. (2003) (12)
11-oxygenated C 19 steroids are the predominant androgens in polycystic ovary syndrome (2016) (12)
Residual Adrenal Function in Autoimmune Addison’s Disease—Effect of Dual Therapy With Rituximab and Depot Tetracosactide (2019) (12)
Self- and proxy-reported outcomes after surgery in people with disorders/differences of sex development (DSD) in Europe (dsd-LIFE). (2020) (12)
Final Height in Relation to Health Outcomes in Adults with Congenital Adrenal Hyperplasia: United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE) (2014) (11)
Comment on primary localization of an ectopic ACTH-producing bronchial carcinoid tumor by indium111 pentetreotide scintigraphy. (1999) (11)
A rare cause of congenital adrenal hyperplasia: Antley-Bixler syndrome due to POR deficiency. (2011) (11)
The adrenal cortex and sexual differentiation during early human development (2009) (11)
Simulation via instant messaging-Birmingham advance (SIMBA) model helped improve clinicians’ confidence to manage cases in diabetes and endocrinology (2019) (11)
Incidence, risk factors and clinical significance of postoperative haemodynamic instability after adrenalectomy for phaeochromocytoma. (2019) (11)
The modulation of corticosteroid metabolism by hydrocortisone therapy in patients with hypopituitarism increases tissue glucocorticoid exposure. (2015) (11)
S-GRAS score for prognostic classification of adrenocortical carcinoma: an international, multicenter ENSAT study (2021) (11)
Novel methods in adrenal research: a metabolomics approach (2019) (10)
Clinical Spectrum of Primary Adrenal Lymphoma: Results of a Multicenter Cohort Study. (2020) (9)
Insights from the genetic characterization of central precocious puberty associated with multiple anomalies. (2020) (9)
Comparison of strategies to learn from imbalanced classes for computer aided diagnosis of inborn steroidogenic disorders (2017) (9)
Neutrophil function in young and old caregivers. (2016) (9)
Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion (2020) (9)
A liquid chromatography-tandem mass spectrometry assay for the profiling of classical and 11-oxygenated androgens in saliva (2019) (9)
Results of the ADIUVO Study, the First Randomized Trial on Adjuvant Mitotane in Adrenocortical Carcinoma Patients (2021) (9)
Rare and common genetic determinants of metabolic individuality and their effects on human health (2022) (8)
Oral glucose tolerance testing but not intravenous glucose administration uncovers hyper‐responsiveness of hypothalamo–pituitary–adrenal axis in patients with adrenal incidentalomas (2000) (8)
A feminizing adrenocortical carcinoma in the context of a late onset 21-hydroxylase deficiency. (2014) (8)
A novel high-throughput assay for the measurement of salivary progesterone by liquid chromatography tandem mass spectrometry (2018) (8)
Exploration of knowledge and understanding in patients with primary adrenal insufficiency: a mixed methods study (2017) (7)
Gonadectomy In Conditions Affecting Sex Development - A Registry-Based Cohort Study. (2021) (7)
11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool (2020) (7)
Simultaneous parameter estimation and variable selection via the logit-normal continuous analogue of the spike-and-slab prior (2018) (7)
Management of the androgen-deficient woman. (2003) (7)
Nutritional supplement (2020) (7)
46,XY Disorder of Sex Development in a Sudanese Patient Caused by a Novel Mutation in the HSD17B3 Gene (2014) (7)
Acute Hypercortisolemia Exerts Depot-Specific Effects on Abdominal and Femoral Adipose Tissue Function (2017) (7)
Increased central adiposity and decreased subcutaneous adipose tissue 11β‐hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance—A longitudinal cohort study (2019) (7)
Adrenal crisis causing critical illness related reversible myocardial dysfunction (2008) (7)
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens. (2020) (6)
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo (2020) (6)
Synergistic effects of ageing and stress on neutrophil function (2009) (6)
Utility of Simulation via Instant Messaging – Birmingham Advance (Simba) in Medical Education during Covid-19 Pandemic (2021) (6)
The natural history of adrenal incidentaloma - results from the international prospective multi-centre EURINE-ACT study (2017) (6)
Learning pharmacokinetic models for in vivo glucocorticoid activation. (2018) (5)
Cardiometabolic Outcomes and Mortality in Patients with Adrenal Adenomas: A Population-Based Cohort Study. (2021) (5)
Relationships between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) (2014) (5)
Residual adrenal function in autoimmune addison s disease effect of dual therapy with rituximab and depot tetracosactide (2018) (5)
Immediate versus modified release hydrocortisone in mitotane‐treated patients with adrenocortical cancer (2017) (5)
Androgen replacement in women. (2007) (5)
Measurement of selected androgens using liquid chromatography–tandem mass spectrometry in reproductive-age women with Type 1 diabetes (2018) (5)
Natural History of Adrenal Steroidogenesis in Autoimmune Addison’s Disease Following Diagnosis and Treatment (2020) (5)
Relevance Learning Vector Quantization in Variable Dimensional Spaces (2016) (5)
AKR 1 C 3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome (2017) (5)
Quality of Life in Men With Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency (2021) (5)
Abiraterone switches castration‐resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling (2022) (5)
Diagnosis and management of adrenal insuffi ciency (2015) (5)
11b-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial (2020) (4)
Multicenter case series of primary adrenal lymphoma (2016) (4)
First randomized trial on adjuvant mitotane in adrenocortical carcinoma patients: The Adjuvo study. (2022) (4)
Polycystic ovary syndrome and risk of adverse obstetric outcomes: a retrospective population-based matched cohort study in England (2022) (4)
Dehydroepiandrosterone substitution in women. (1999) (4)
11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool. (2021) (4)
Association between hypercortisolaemia and adipose tissue blood flow in vivo (2015) (4)
Validation of circulating steroid hormone measurements across different matrices by liquid chromatography–tandem mass spectrometry (2021) (3)
Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review (2020) (3)
Dehydroepiandrosterone (DHEA) and androstenedione (2001) (3)
Altered cortisol metabolism in individuals with HNF1A-MODY. (2020) (3)
Hyperandrogenaemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione (2014) (3)
Dehydroepiandrosterone supplementation in elderly men: the role of estrogens versus androgens on the male skeleton. (2002) (3)
Relationship of current glucocorticoid dose with metabolic outcomes in CAH: analysis of the United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE) cohort (2012) (3)
Outcome of non-functioning pituitary adenomas that regrow after primary treatment: a study from two large specialist UK centers (2017) (3)
[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial (2023) (3)
A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT (2021) (3)
Mitotane treatment in patients with metastatic testicular Leydig cell tumor associated with severe androgen excess (2018) (3)
Improving Data Quality in Disease Registries and Clinical Trials: A Case Study from the ENSAT-CANCER Project (2015) (3)
Pathology and (3)
Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery in adrenal insufficiency (2020) (3)
University of Birmingham Diagnosis and management of adrenal insufficiency (2016) (3)
Urine steroid metabolomics as a diagnostic tool in primary aldosteroinism (2015) (3)
Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomized controlled trial (2022) (3)
The endocrine response to severe trauma: the Steroids and Immunity from injury to Rehabilitation (SIR) study (2014) (3)
The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series (2021) (3)
Polycystic Ovary Syndrome, Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study (2021) (3)
Monogenic forms of hyperandrogenism due to defects in cortisol metabolism (2007) (2)
11-Ketotestosterone is the Predominant Androgen in Castration Resistant Prostate Cancer (2020) (2)
Adrenocortical insufficiency in Rhodesian sleeping sickness is not attributable to suramin. (1995) (2)
The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy (2020) (2)
OR25-02 A Phase 3 Study of a Modified-Release Hydrocortisone in the Treatment of Congenital Adrenal Hyperplasia (2020) (2)
SIMBA: using Kolb’s learning theory in simulation-based learning to improve participants’ confidence (2021) (2)
Reply to Flück et al.: Alternative androgen pathway biosynthesis drives fetal female virilization in P450 oxidoreductase deficiency (2020) (2)
Steroid metabolomics for accurate and rapid diagnosis of inborn steroidogenic disorders (2017) (2)
26th International Congress of the European Association for Endoscopic Surgery (EAES), London, United Kingdom, 30 May–1 June 2018: Poster Presentations (2018) (2)
Supine or sitting plasma metanephrine screening? A unifying solution for patients and doctors (2015) (2)
Urine steroid metabolomics is a highly sensitive tool for post-operative recurrence detection in adrenocortical carcinoma (2016) (2)
Junior doctors' working hours and the circadian rhythm of hormones. (2006) (2)
Consider Addison’s disease in differential diagnosis of eating disorders in children and young people (2018) (2)
[Postpartum rupture of a kidney cyst in familial polycystic kidney degeneration and HELLP syndrome]. (1996) (2)
DHEA replacement in adrenal insufficiency. Authors' reply (2003) (2)
The immune-endocrine mechanisms of trauma-induced sarcopenia (2014) (2)
[Treatment of metastatic adrenal carcinoma with suramin]. (1989) (2)
TAC3/TACR3 Mutations Reveal Preferential Activation of GnRH Release by Neurokinin B in Neonatal Life Followed by Reversal in Adulthood (2010) (2)
Broad phenotypic spectrum of 17[alpha]-hydroxylase deficiency: Functional characterisation of 4 novel mutations in the CYP17A1 gene (2012) (2)
Results of the ADIUVO trial, the first randomized study on post-operative adjuvant mitotane in patients with adrenocortical carcinoma (2021) (2)
Current management, morbidity and genotypephenotype correlation in adults with congenital adrenal hyperplasia – analysis of the United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE) cohort [Abstract] (2009) (2)
The Endocrine and Metabolic Response in Male Survivors of Major Trauma (2019) (2)
Concurrent analysis of 10 serum steroids by mass spectrometry: investigation of the viability of the Perkin-Elmer CHS[trade] MSMS steroids kit on a waters xevo mass spectrometer with acquity UPLC system (2011) (2)
11-Ketotestosterone is the predominant active androgen in prostate cancer patients after castration (2021) (2)
Global impact of PCOS awareness month: challenges and opportunities (2022) (2)
Modified GRAS Score for Prognostic Classification of Adrenocortical Carcinoma: An ENSAT Multicentre Study (2020) (2)
The adult with CAH: results of the UK congenital adrenal hyperplasia, adult study executive (CaHASE) (2010) (1)
Prevalence of obesity and its association with metabolic diseases in women from low-and-middle income countries (LMICs): A systematic review and meta-analysis (2021) (1)
Staging of non-alcoholic fatty liver disease through LC-MS/MS analysis of the urinary steroid metabolome (2018) (1)
Can dehydroepiandrosterone or testosterone replacement effectively treat the symptoms of aging? (2007) (1)
Intracrine activation of 11-oxygenated androgens by AKR1C3 modulates lipid metabolism in human female adipose tissue (2019) (1)
Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency (2020) (1)
Impaired DHEA sulfation defines androgen excess in women with polycystic ovarian syndrome (PCOS) (2016) (1)
Steroid sulfatase contributes to systemic androgen activation in pre-pubertal boys: lessons from steroid sulfatase deficiency (2014) (1)
Clinical qualification of plasma androgen receptor (pAR) status and outcome on abiraterone acetate (AA) plus prednisone or dexamethasone (+P/D) in a phase II multi-institutional study in metastatic castration resistant prostate cancer (mCRPC). (2018) (1)
University of Birmingham Bilateral testicular tumors resulting in recurrent Cushing's syndrome after bilateral adrenalectomy (2016) (1)
The spectrum of associated congenital anomalies in disorders of sex development: a review of the I-DSD Registry (2013) (1)
Gonadectomy for adults with DSD conditions at risk of hypogonadism in the international disorders of sex development registry (2018) (1)
Timed urinary steroid profiling of patients with different degrees of cortisol excess: a proposal for a new test for the diagnosis of Cushing's syndrome (2018) (1)
Effect of IL-1 receptor antagonism on hyperandrogenemia in women with polycystic ovary syndrome (2021) (1)
Impaired quality of life in patients with adrenal insufficiency evidence that improved glucocorticoid replacement strategies are needed (2006) (1)
A systematic review of lived experiences of people with polycystic ovary syndrome highlights the need for holistic care and co-creation of educational resources (2022) (1)
Suramin in adrenocortical cancer (1994) (1)
T cell immunity and caregiving stress in young and older caregivers (2015) (1)
Multi-parametric cardiovascular magnetic resonance imaging detects subclinical myocardial involvement in patients diagnosed with phaeochromocytoma (2015) (1)
University of Birmingham Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty (2016) (1)
The urinary steroid metabolome as a non-invasive tool to stage non-alcoholic fatty liver disease (2016) (1)
Increased infection risk in Addison’s disease and congenital adrenal hyperplasia: a primary care database cohort study (2019) (1)
Pubertal Presentation in Congenital Adrenal Hyperplasia Due to P450 Oxidoreductase Deficiency. (2010) (1)
Diagnosis and Management of Congenital Adrenal Hyperplasia in Children and Adults (2019) (1)
Adrenal emergency is a regular event for treated Addison's patients (2008) (1)
Prevention of adrenal crisis in stress (The PACS Study): serum cortisol during elective surgery, acute trauma and sepsis in comparison to 'stress dose' hydrocortisone administration in adrenal insufficiency (2015) (1)
Corticosteroids in critically III patients : A long and winding rood. Author's reply (2006) (1)
Improving diabetes and endocrinology specialty training with modest resources: the Health Education West Midlands model (2021) (1)
A randomised controlled pilot trial of oral 11Î²-HSD1 inhibitor AZD4017 for wound healing in adults with type 2 diabetes mellitus (2021) (1)
Testosterone: Dehydroepiandrosterone and androstenedione (2012) (1)
Biochemical and clinical characteristics of polysystic ovarian syndrome (PCOS) in women with and without type 1 diabetes (TID) (2017) (1)
Interpretable Models Capable of Handling Systematic Missingness in Imbalanced Classes and Heterogeneous Datasets (2022) (1)
Urinary Steroid Profiling as a High-Throughput Screening Tool for the Detection of Malignancy in Patients with Adrenal Tumors (2010) (1)
Congenital Adrenal Hyperplasia : The Lancet Seminar Series (2017) (1)
Adrenal tumours and hormone excess. Editorial. (2009) (1)
Diagnostic Work-Up and Nonsurgical Management of Pituitary Disease (2014) (1)
Androgen excess is highly prevalent in women with idiopathic intracranial hypertension and is biochemically distinct from polycystic ovary syndromes (2017) (1)
122 Cardiac Abnormalities are Common in Patients Diagnosed with Phaeochromocytoma as Detected by Cardiovascular Magnetic Resonance Imaging (2014) (1)
[Paraneoplastic hypertrichosis lanuginosa et terminalis in a 27-year old woman with parotid carcinoma]. (1999) (1)
Adrenal function testing in 273 patients with severe sepsis reveals baseline cortisol as a reliable predictor of outcome (2008) (1)
Steroid biomarkers and the diagnosis of adrenal cortical carcinoma (2019) (1)
Impaired quality of life in CAH adults is associated with adiposity and insulin resistance (2013) (1)
Mild autonomous cortisol excess in adrenal incidentalomas - metabolic disease burden and urinary steroid metabolome in 1201 prospectively recruited patients (2017) (1)
Neuroendocrine Activation (2020) (1)
THE ANDRO-METABOLIC SIGNATURE OF IIH COMPARED WITH PCOS AND SIMPLE OBESITY (2016) (1)
The role of androgens in PCOS-related insulin resistance (2015) (1)
In the arena of adrenal disorders significant progress has been made over the last few years. Preface. (2009) (1)
Simulation via instant messaging − birmingham advance (SIMBA) as a tool to bridge gaps in clinical knowledge and expectations between physicians and patients with polycystic ovary syndrome (2022) (0)
Modified-release hydrocortisone improves androgen excess and facilitates glucocorticoid dose reduction in patients with classic congenital adrenal hyperplasia: non-invasive monitoring in saliva and urine (2021) (0)
Testosterone enhances GLP-1 efficacy at the plasma membrane and endosomes to augment insulin secretion in male pancreatic β cells (2020) (0)
24-hour urinary glucocorticoid metabolites are associated with hyperinsulinaemia independent of BMI in patients with the polycystic ovary syndrome (2012) (0)
Demographics of adrenal incidentaloma - results from an international prospective multi-centre study in 2190 patients (2016) (0)
Use of the morning urinary cortisol to creatinine ratio in the diagnosis of mild Cushing's disease in patients with discordant test results (2008) (0)
20 year experience in the surgical management of cushing's disease in a UK tertiary referral centre (2011) (0)
Assessment of Steroid Hormones in Both Saliva and Blood During a Phase 2 Clinical Trial for the Use of Tildacerfont in Adults With Classic Congenital Adrenal Hyperplasia (2021) (0)
Relationship between final height and cardiometabolic risk and quality of life in adults with congenital adrenal hyperplasia: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) (2014) (0)
Isolated ACTH deficiency as a cause of impaired well-being in patients with primary hypothyroidism (2008) (0)
Phenotypic presentation of P450 oxidoreductase deficiency during puberty (2010) (0)
Differential impact of PAPS synthases on human sulfation pathways (2014) (0)
16. Androgen metabolism in tissue slice cultures of CRPC patients tissue, a metabolic biopsy: Castration-resistant prostate tumor tissue synthesizes testosterone itself (2014) (0)
Molecular basis of a new form of congenital adrenal hyperplasia (2004) (0)
[Adrenal cortex insufficiency: diagnosis and therapy]. (1999) (0)
University of Birmingham Pheochromocytoma is Characterized By Catecholamine Myocarditis, Focal and Diffuse Fibrosis, and Persistent Subclinical Systolic and Diastolic Dysfunction (2016) (0)
Modelling the salivary cortisone to serum cortisol inter-relationship to predict serum cortisol under physiological conditions and after hydrocortisone (2015) (0)
University of Birmingham Influence of 17-Hydroxyprogesterone, Progesterone and Sex Steroids on Mineralocorticoid Receptor Transactivation in Congenital Adrenal Hyperplasia (2016) (0)
Development of urinary steroid profiling as a high-throughput screening tool for the detection of malignancy in patients with adrenal tumours (2010) (0)
Antioxidant pathway targeting as a therapeutic approach in adrenocortical carcinoma (2017) (0)
Androgen profiling by liquid chromatography-mass spectrometry (LC-MS) in reproductive-age women with and without diabetes (2017) (0)
[Malignant tumors of the adrenal cortex]. (2002) (0)
PCOS SEVa: High prevalence anxiety and body dysmorphia in women with PCOS in the UK and India (2021) (0)
Functional characterisation of 21-hydroxylase gene mutations is a valuable tool for genetic counselling: in vitro and in silico analysis of six novel CYP21A2 sequence variants (2010) (0)
University of Birmingham Monogenic disorders of adrenal steroidogenesis (2018) (0)
P450 oxidoreductase and androgen metabolism (2006) (0)
Management of adrenal disorders in pregnancy (2011) (0)
Identification of clinical parameters predictive of ARMC5 mutation in a large cohort of primary bilateral macronodular adrenal hyperplasia (PBMAH) patients. (2020) (0)
The effect of adrenalectomy on cardiovascular morbidity in adrenal tumor patients with subclinical Cushing's syndrome: systematic review and meta-analysis (2015) (0)
Genes Presenting with 46 , XY Disordered Sex Development and Androgenization Concomitant Mutations in the P 450 Oxidoreductase and Androgen Receptor (2010) (0)
Glucocorticoid Deficiency Nonclassic Lipoid Congenital Adrenal Hyperplasia Masquerading as Familial (2009) (0)
Altered steroid metabolism in patients following severe trauma: the golden hour study (2022) (0)
Polycystic ovary syndrome ( PCOS ) , androgen excess and the risk of non-alcoholic fatty liver disease ( NAFLD ) in women : a longitudinal study based on a UK primary care database (2018) (0)
Using a morning cortisol to predict adrenal reserve and guide management (2015) (0)
Cardiometabolic disease burden and urine steroid metabolome in benign adrenocortical tumours: a case-control study (2021) (0)
SIMBA for Students: teaching preclinical medical and pharmacy students endocrinology through online simulation - a pilot study (2022) (0)
Replicating the normal cortisol circadian rhythm using a formulation of modified-release hydrocortisone (2009) (0)
University of Birmingham Measurement of selected androgens using liquid chromatography-tandem mass spectrometry in reproductive-age women with Type 1 diabetes (2018) (0)
tandem mass spectrometry : utility for diagnosis of dopamine-producing metastatic − chromatography Analysis of plasma 3-methoxytyramine , normetanephrine and metanephrine by ultraperformance liquid (2013) (0)
Further advances in diagnosis of adrenal cancer: a high-throughput urinary steroid profiling method using liquid chromatography tandem mass spectrometry (LC-MS/MS) (2015) (0)
Steroid metabolomics for diagnosis of inborn steroidogenic disorders – bridging the gap between clinician and scientist through computational approaches (2016) (0)
Immunesenescence and steroid hormones (2007) (0)
The German Adrenocortical Carcinoma (ACC) Registry – establishment and first results (2004) (0)
Urinary steroid metabolomics for adrenocortical cancer diagnosis. Comparison of gas chromatography mass spectrometry to liquid chromatography mass spectrometry (2022) (0)
Circulating cell-free DNA for prognostication and disease surveillance in adrenocortical carcinoma (2021) (0)
Combined pituitary hormone deficiency (CPHD) with adult-onset corticotropin deficiency but without evidence for PROP-1 or HESX1 mutations (2003) (0)
Vanishing bone: Stabilisation of Gorham-Stout disease during antiresorptive therapy (2003) (0)
Contents Vol. 83, 2015 (2015) (0)
277 AR driven growth in CRPC depends predominantly on androgen precursors secreted by the adrenal gland (2015) (0)
5[beta]-reductase (AKR1D1) is a potent regulator of carbohydrate and lipid metabolism and inflammation in human liver (2017) (0)
The differential impact of PAPS synthase isoforms on DHEAS may be explained by an isoform-specific interaction of SULT2A1 with PAPSS2, but not PAPSS1 (2015) (0)
Validation of multiplex steroid hormone measurements in prostate cancer using plasma for multimodality biomarker studies (2020) (0)
Urinary steroid profiling demonstrates induction of CYP3A4 and inhibition of 5alpha-reductase by mitotane treatment for adrenocortical carcinoma (2012) (0)
Assessing anxiety, depression and body dysmorphia in young women with and without PCOS: the Blue Morpho Gen Y Survey (2021) (0)
Normothermic machine liver perfusion as a tool to study human androgen metabolism (2022) (0)
Sex, electrons and the adrenal - why endocrinology excites (2009) (0)
What lies beneath: cutaneous Kaposi's sarcoma as a first manifestation of ectopic ACTH-dependent Cushing's syndrome (2018) (0)
Multiplex serum steroid profiling using liquid chromatography mass spectrometry with post column infusion ammonium fluoride (2022) (0)
COVID‐19‐related adrenal haemorrhage: Multicentre UK experience and systematic review of the literature (2023) (0)
Women with idiopathic intracranial hypertension have a distinct andro-metabolic signature compared to polycystic ovary syndrome and simple obesity (2016) (0)
[Cushing syndrome: diagnosis and therapy]. (1999) (0)
Evidence for the existence and significance of an alternative pathway towards androgen synthesis during early human life (2011) (0)
Differential roles of PAPSS1 and PAPSS2 in the control of androgen synthesis (2010) (0)
Characterisation of seven novel 11[beta]-hydroxylase (CYP11B1) gene mutations: three severe and four mild mutations (2008) (0)
11-oxygenated C19 Steroids in Normal Weight, Overweight, and Hyperandrogenic Girls and Pituitary (2020) (0)
The changing 'steroid metabolome' across the spectrum of non-alcoholic fatty liver disease (2016) (0)
Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation. (2023) (0)
Androgen replacement therapy in women. (2012) (0)
Pathophysiology and genetics of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency (2005) (0)
Urinary Glucocorticoid Metabolite Excretion is Associated with Insulin Resistance Independent of BMI in Patients with Polycystic Ovary Syndrome (2012) (0)
Characterising fat distribution and response to weight loss in idiopathic intracranial hypertension (2015) (0)
Impact of menopause on the natural history of pre-existing prolactinomas (2017) (0)
The diverse manifestations of impaired androgen biosynthesis (2006) (0)
DHEA but not DHEAS exerts anti-glucocorticoid action in human preadipocytes (2007) (0)
Abstract C97: Beyond intratumoural steroidogenesis: abiraterone resistance mediated by AR variants and glucocorticoid receptor signalling (2015) (0)
Advantages in the measurement of steroid hormones (2014) (0)
Steroid Metabolomics : A Powerful Technique for Differentiating Inborn Disorders of Steroidogenesis (2018) (0)
A Prospective Cross-Over Study of Tissue Glucocorticoid Metabolism in Patients With Adrenal Insufficiency: The Effects of Dual-Release Hydrocortisone Therapy (2021) (0)
Urinary steroid profiling as a biomarker tool for the detection of adrenal malignancy: results of the EURINE ACC Study (2009) (0)
Prenatal diagnosis of the low-oestriol disorders Smith-Lemli-Opitz syndrome (SLOS), oxidoreductase deficiency (ORD) and sulfatase deficienciy (STSD) (2006) (0)
PCOS pearls - gathering perceptions and opinions from lived experiences of people with polycystic ovary syndrome (2021) (0)
dsd-LIFE: clinical European outcome study of disorders of sex development (2014) (0)
Cortisol, DHEA and DHEAS in severe sepsis - a paradigm revisited (2005) (0)
Interventions for preventing adrenal crisis - behavioural insights (2022) (0)
A defect in the DHEA-DHEAS shuttle defines a novel cause of polycystic ovary syndrome (2005) (0)
Increased risk of infections in Addison's disease and congenital adrenal hyperplasia patients: a longitudinal study based on a United Kingdom primary care database (2019) (0)
Nicotinamide nucleotide transhydrogenase (NNT) as a novel molecular target in adrenocortical carcinoma - impact of NNT knockdown on adrenocortical cell proliferation, redox balance and steroidogenesis (2015) (0)
Phenotypic variability in P450 oxidoreductase deficiency may be caused by differential effects of P450 oxidoreductase mutations on steroidogenesis (2006) (0)
RNA Sequencing Reveals the Pathways Perturbed by Redox Imbalance in Nicotinamide Nucleotide Transhydrogenase Null Mice (2015) (0)
Expanding the clinical and genetic spectrum of 17α-Hydroxylase/17,20-Lyase deficiency: 7 cases and 5 novel mutations in the CYP17A1 gene (2020) (0)
Classic and 11-oxygenated androgens in serum and saliva across adulthood and the menstrual cycle - a mass spectrometry-based cross-sectional study (2021) (0)
Severe glucorticoid deficiency in 17-hydroxylase deficiency - novel mutation in the CYP17A1 gene (2009) (0)
Identification and functional impact of novel mutations in the gene encoding 11[beta]-hydroxysteroid dehydrogenase type 1 in patients with hyperandrogenism (2010) (0)
Society for Endocrinology Medal Lecture (2010) (0)
Steroid metabolomics in adrenocortical carcinoma reveals mitotane as an inducer of CYP3A4 and an inhibitor of 5alpha-reductase activity with major implications for drug metabolism and hydrocortisone replacement (2012) (0)
Glucocorticoid metabolism in human obesity; increased 5[alpha]-reductase activity is associated with insulin resistance in both men and women (2008) (0)
Reduced temperature and the chemical chaperone 4-phenylbutyrate enhance stability of CYP21A2 mutations (2016) (0)
Modifying impact of 17-hydroxyprogesterone and sex steroids on mineralocorticoid receptor transactivation by aldosterone (2012) (0)
PCOS pearls - findings from the qualitative study assessing the lived experience of people with polycystic ovary syndrome (2022) (0)
203 Patients Health Status of Adults with Congenital Adrenal Hyperplasia: A Cohort Study of (2010) (0)
Response to Letter to the Editor: “Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery” (2020) (0)
Simulation via Instant Messaging - Birmingham Advance (SIMBA): First steps towards standardising online simulation-based learning in clinical endocrinology (2021) (0)
Comparison of prednisolone and modified-release hydrocortisone capsules in the treatment of congenital adrenal hyperplasia: dose and disease control (2022) (0)
Progesterone inactivation in human osteoblasts (2005) (0)
Lack of Hepatic Conversion of Dehydroepiandrosterone Sulfate (DHEAS) to DHEA (2004) (0)
P450 oxidoreductase deficiency at puberty in a 46, XY individual with Antley-Bixler syndrome (2009) (0)
RNA-sequencing of mouse adrenals reveals the pathways perturbed by loss of nicotinamide nucleotide transhydrogenase (2015) (0)
Functionally significant reductions in white matter in patients with congenital adrenal hyperplasia (2016) (0)
Faculty Opinions recommendation of A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. (2006) (0)
11 2-Hydroxylase Deficiency Mutations Associated with Nonclassic and Three Mutations Causing Classic Gene : FourCYP 11 B 1 Functional Consequences of Seven Novel Mutations in the Society (2010) (0)
Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase (2015) (0)
Novel brain biomarkers of cognitive abnormalities identified in patients with congenital adrenal hyperplasia (2016) (0)
Sex steroid biosynthesis in human peripheral blood mononuclear cells changes with aging (2004) (0)
11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool. (2021) (0)
Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance (2016) (0)
University of Birmingham 11-hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension (2020) (0)
Hyperandrogenaemia in women with type 1 diabetes mellitus; associations with lipids and lipoprotein particle size, and early vascular disease (2018) (0)
Response Letter to the Editor from Sweeney AT: "CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma". (2020) (0)
Mass spectrometry-based assessment of childhood androgen excess in 487 consecutive patients (2018) (0)
Evaluation of Molecular Characteristics and Steroid Metabolomics in a Large Cohort of Children with 3β-Hydroxysteroid Dehydrogenase 2 Deficiency (2019) (0)
Circulating cell-free DNA-based biomarkers as a tool for disease surveillance in adrenocortical carcinoma (2021) (0)
Steroid metabolome analysis reveals that prostate cancer has potent 5[alpha]-reductase, 3[alpha]- and 17[beta]-hydroxysteroid dehydrogenase activities, but lacks 17-hydroxylase/17,20-lyase (2015) (0)
9. Newly Diagnosed Adrenal Insufficiency (2010) (0)
Gonadectomy for Adults with DSD Conditions in the International Disorders of Sex Development Registry (2018) (0)
Defining 17[alpha]-hydroxylase in zebrafish: expression pattern of two paralog genes (zCyp17a1; zCyp17a2) and comparative in vitro and in silico analysis (2012) (0)
Mass Spectrometry-Based Assessment of Childhood Androgen Excess in 487 Consecutive Patients Over 5 Years (2018) (0)
PF311 ISOLATED PRIMARY ADRENAL LYMPHOMA (IPAL) - AN EMERGING LYMPHOMA ENTITY? RESULTS OF A RETROSPECTIVE MULTICENTER STUDY (2019) (0)
RF12 | PSUN117 Sex-Specific Obesity and Cardiometabolic Disease Risks In Low- and Middle-Income Countries: A Meta-Analysis Involving 2,624,289 Individuals (2022) (0)
Prediction of Germ Cell Cancer Occurrence in Postpubertal Individuals with Androgen Insensitivity Based on Pathological Findings and Cancer Predisposition SNPs (2015) (0)
Thyroid dysfunction in African trypanosomiasis (1993) (0)
Quality of life in adult patients with congenital adrenal hyperplasia - results of the congenital adrenal hyperplasia adult study executive (2009) (0)
University of Birmingham Health Status of Adults with Congenital Adrenal Hyperplasia: A Cohort (2010) (0)
How would school children design a poster about diabetes, obesity, health technologies and emotional wellbeing awareness? (2021) (0)
Truncal fat distribution is associated with enhanced glucocorticoid excretion, increased 5[alpha]-reductase activity and higher insulin resistance independent of BMI in women with polycystic ovary syndrome (2013) (0)
Dehydroepiandrosterone inhibits differentiation, proliferation and 11β-hydroxysteroid dehydrogenase type 1 activity in human preadipocytes (2006) (0)
University of Birmingham Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia (2017) (0)
Radiation-induced hypothalamic-pituitary damage in long term survivors of primary brain tumours is reflected by endocrine dysfunction and impaired health-related quality of life (2008) (0)
Steroid replacement: an unusual alternative to oral therapy via 24-h s.c. infusion device (2010) (0)
A case of unilateral post-COVID-19 adrenal haemorrhage and follow-up during pregnancies (2022) (0)
Differential effects of P450 oxidoreductase mutants on CYP17 activity provides evidence for an alternative pathway in human androgen biosynthesis (2007) (0)
OR09-5 Importance of Islet Intracrinology for Glucose-Stimulated Insulin Secretion (GSIS) in the Male (2019) (0)
Bilateral adrenal haemorrhage. (2017) (0)
Urine metabolomic phenotyping for detection of adrenocortical carcinoma: still a long way to go - Authors' reply. (2020) (0)
Increased risk of cardiometabolic disease in patients with benign adrenal tumours with and without cortisol excess: a casecontrol study (2021) (0)
PAPS synthase 2 is the major PAPS-supplying enzyme for DHEA sulfation (2017) (0)
Phase 3 and extension study of modified-release hydrocortisone in the treatment of congenital adrenal hyperplasia (2021) (0)
University of Birmingham Mapping the steroid response to major trauma from injury to recovery (2020) (0)
Therapeutic management of adults with CAH (2012) (0)
The ultra-acute steroid response to traumatic injury: a cohort study. (2023) (0)
University of Birmingham Congenital Adrenal Hyperplasia: The Lancet Seminar Series (2017) (0)
Running head : Caregiving and neutrophil function Neutrophil function in young and old caregivers (2015) (0)
University of Polycystic ovary syndrome (PCOS), androgen excess and the risk of non-alcoholic fatty liver disease (NAFLD) in women: a longitudinal study based on a UK primary care database (2018) (0)
[A hairy case]. (1999) (0)
Impact of mutant P450 oxydoreductase on metabolic capacity of cytochrome P450 enzymes (2009) (0)
OR29-2 Mild Autonomous Cortisol Excess (MACE) in Adrenal Incidentalomas - Metabolic Risk Profile and Urinary Steroid Metabolome Analysis in 1208 Prospectively Recruited Patients (2019) (0)
Progressive adrenal insufficiency and 46,XY DSD caused by two novel mutations in the cytochrome P450 side-chain cleavage (CYP11A1) gene (2012) (0)
Phenotypic variability of 17[alpha]-hydroxylase (CYP17A1) deficiency (2011) (0)
Modelling oral adrenal cortisol support (2020) (0)
Urinary glucocorticoid metabolite excretion is associated with insulin resistance independent of body mass index (BMI) in patients with polycystic ovary syndrome (2012) (0)
CHARACTERISING FAT DISTRIBUTION AND RESPONSE TO WEIGHT LOSS IN IIH (2016) (0)
Response to Letter to the Editor from Chee et al: “Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery” (2020) (0)
Functional and structural analysis of three novel mutations (A174E, V178D, L465P) in the CYP17A1 gene causing steroid 17-hydroxylase deficiency (2008) (0)
Associated health conditions and occupational status are risk factors for adrenal crisis in treated Addison's disease (2009) (0)
Incident Cardiometabolic Outcomes in Adrenal Adenomas: A Population-Based Cohort Study of 1,004 Patients (2021) (0)
Fertility in congenital adrenal hyperplasia (CAH) patients on modified release hydrocortisone capsules (MRHC, Efmody) (2022) (0)
Steroid deconjugation by helix pomatia - can we overcome snail speed? (2019) (0)
Mass spectrometry-based assessment of androgen excess in 1205 consecutive patients over 5 years: PCOS most common diagnosis, but severe androgen excess indicates other ovarian and adrenal pathology (2017) (0)
University of Birmingham 11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome (2017) (0)
Urine steroid metabolomics as a novel diagnostic tool for recurrent adrenocortical carcinoma detection (2019) (0)
Hypercortisolaemia increases femoral adipose tissue blood flow but not net fatty acid release in vivo (2015) (0)
Outcomes of bilateral adrenalectomy in ACTH-dependent Cushing's syndrome (2018) (0)
Steroid and global metabolome in benign adrenal tumours with mild autonomous cortisol secretion: analysis by mass spectrometry and machine learning to understand metabolic risk (2022) (0)
Simultaneous Parameter Estimation and Variable Selection via the LN-CASS Prior (2018) (0)
Stressed to death - antioxidant pathway targeting as a novel therapeutic approach in adrenocortical carcinoma (2016) (0)
Unusually mild phenotypic presentation in a family with CYP17A1 deficiency detected by urinary steroid profiling (2007) (0)
Assessing emotional wellbeing in women with PCOS living in the UK and Indian community: the Blue Morpho Survey (2021) (0)
Modified-release hydrocortisone is associated with lower plasma renin activity in patients with salt-wasting congenital adrenal hyperplasia. (2023) (0)
University A novel high-throughput assay for the measurement of salivary progesterone by liquid chromatography tandem mass spectrometry (2018) (0)
Accurate staging of non-alcoholic fatty liver disease through analysis of the urinary steroid metabolome (2017) (0)
RF09 | PSAT70 Comparison of Prednisolone Versus Modified-release Hydrocortisone (Efmody) in the Treatment of Congenital Adrenal Hyperplasia (CAH) (2022) (0)
Functional and structural characterisation of three CYP21A2 mutations associated with simple virilising and non classic congenital adrenal hyperplasia (2008) (0)
Mitotane ameliorates testostoxicosis due to metastatic Leydig cell tumour (2014) (0)
University of Groningen Comparison of strategies to learn from imbalanced classes for computer aided diagnosis of inborn steroidogenic disorders Ghosh, (2018) (0)
Comment on "A Modern Assessment of Cancer Risk in Adrenal Incidentalomas: Analysis of 2219 Patients" by Kahramangil B et al. (2021) (0)
A case series report on outcome of fertility treatment in thalassemia major patients (2012) (0)
OR27-07 11-oxygenated C19 Steroids in Normal Weight, Overweight, and Hyperandrogenic Girls (2020) (0)
PCOS SEVa: High prevalence anxiety and body dysmorphia in women with PCOS attending specialist care in the UK and India (2022) (0)
Double trouble: two cases of dual adrenal pathologies in one adrenal mass (2019) (0)
Switching patients with Congenital Adrenal Hyperplasia to Modified release hydrocortisone capsules: relative bioavailability and disease control (2023) (0)
Should the 1 mg -overnight dexamethasone suppression test be repeated in patients with benign adrenal incidentalomas and no overt hormone excess? (2021) (0)
A systematic review and meta-analysis assessing psychosexual wellbeing in people with polycystic ovary syndrome (2022) (0)
Male sex hormone and reduced plakoglobin jointly impair atrial conduction and cardiac sodium currents (2022) (0)
5[beta]-reductase (AKR1D1) is a potent regulator of hepatic insulin sensitivity, carbohydrate and lipid metabolism in vitro and in vivo (2018) (0)
Emotional and psychosexual wellbeing is influenced by ethnicity and birthplace in women and individuals with polycystic ovary syndrome in the UK and India. (2023) (0)
Resistance to thyroid hormone alpha: molecular, biochemical and physiological approach to diagnosis and therapy (2022) (0)
The trick is the combination (2008) (0)
A novel method for analysis of 11 oestrogens using high-throughput liquid chromatography tandem mass spectrometry (2019) (0)
Glucocorticoid regimen options in combination with abiraterone acetate: an international, multicenter, randomized, open-label phase 2 study (2019) (0)
Direct measurement of adrenal DHEA and DHEAS secretion provides evidence for a pivotal role of extraadrenal sulphonation for peripheral DHEA availability (2006) (0)
Abstract GMM-032: UNRAVELLING THE STEROID METABOLOME IN EPITHELIAL OVARIAN CANCER (2019) (0)
Novel methods in adrenal research: a metabolomics approach (2019) (0)
University of Birmingham A new dawn for androgens (2016) (0)
Perceptions and experiences of women with polycystic ovary syndrome- a systematic review (2022) (0)
Androgenemic Phenotype Predicts Metabolic Disease and Androgen Burden in Polycystic Ovary Syndrome (2013) (0)
Neuroimmunomodulation Editors Induction by Cytokines of the Pattern of Pituitary Hormone 2 Secretion in Infection Impairment of Adrenocortical Function Associated with 14 Increased Plasma Tumor Necrosis Factor-alpha and Interleu- Kin-6 Concentrations in African Trypanosomiasis Release of Immunoreact (0)
Progressive adrenal insufficiency in a patient with 46,XY DSD caused by two novel mutations in the cytochrome P450 side-chain cleavage (CYP11A1) gene (2012) (0)
at Adrenarche Genes Presenting with 46,XY Disordered Sex Development and Androgenization Concomitant Mutations in the P450 Oxidoreductase and Androgen Receptor (2010) (0)
Complex management of unilateral post-Covid-19 adrenal haemorrhage during pregnancy (2021) (0)
Multiple Malformations Extending the Phenotypic Spectrum of Antley-Bixler Syndrome in a Patient with P450 Oxidoreductase Deficiency due to Two Novel Mutations of the POR Gene (2015) (0)
University of Birmingham Molecular and clinical evidence for an ARMC5 tumor syndrome (2016) (0)
Quality of life relates to glucocorticoid treatment regimen, adiposity and insulin resistance in adults with congenital adrenal hyperplasia: UK Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) (2013) (0)
Prolactinomas diagnosed after menopause: presentation and outcomes from a large specialist centre (2017) (0)
Simulation via instant messaging - Birmingham advance (SIMBA): an innovative simulation-based learning model that helped to keep medical education continue during the COVID-19 pandemic. (2021) (0)
From bench to bedside and beyond: a novel therapy to improve wound healing in type 2 diabetes (2019) (0)
Upregulation of subcutaneous adipose AKR1C3 expression in obese females: evidence for depot- and sex-specific effects (2014) (0)
Sunitinib decreases adrenocortical cancer cell proliferation and specifically inhibits adrenal steroidogenesis (2010) (0)
Identification of a duplicated P450 side-chain cleavage enzyme (zCyp11a2) defines initiation and maintenance of steroidogenesis in zebrafish (2013) (0)
Hypospadias in a Male Patient with 21-Hydroxylase Deficiency and Atypical Clinical Course: Presentation of Two Brothers (2014) (0)
Urine steroid metabolome analysis allows for metabolic risk stratification in 1309 prospectively recruited patients with benign adrenal tumours and different degrees of cortisol excess (2019) (0)
Incidence of COVID-19 in People with Primary Adrenal Insufficiency in the UK and Reported Self-Management - A prospective study (2022) (0)
Urine steroid metabolomics as a novel diagnostic tool for early detection of recurrence in adrenocortical carcinoma (2015) (0)
Prenatal diagnosis of P450 oxidoreductase deficiency (2006) (0)
Clinical Endocrinology Trust Award [amp] Lecture (2016) (0)
Insulin upregulates AKR1C3 expression in female adipose tissue: in vivo and in vitro evidence for adipose androgen generation in polycystic ovary syndrome (PCOS) (2014) (0)
Impact of COVID-19 on patients with primary adrenal insufficiency: a cross-sectional study (2021) (0)
SAT-LB002 Steroid Metabolome Analysis Reveals 11-Ketotestosterone as the Most Abundant Androgen in Castration-Resistant Prostate Cancer Patients on Second-Line Therapies (2019) (0)
Bacterial and yeast co-expression studies reveal hexose-6-phosphate dehydrogenase to be a crucial regulator of 11beta-hydroxysteroid dehydrogenase type 1 oxoreductase activity (2004) (0)
PCOS SEVa: High prevalence of anxiety, depression and body dysmorphia in people with PCOS suggesting we need to rethink how we screen and manage emotional wellbeing in people with PCOS (2021) (0)
OR04-5 Circulating Cell-Free DNA-Based Biomarkers For Prognostication and Disease Surveillance in Adrenocortical Carcinoma (2022) (0)
High incidence of cardiac involvement in patients diagnosed with phaeochromocytoma: a clinical study using cardiovascular magnetic resonance imaging (2014) (0)
Differential regulation of 5[beta]-reductase (AKR1D1) expression and activity by glucocorticoids in human and rodent liver (2019) (0)
Introducing the New Faces of Endocrine Reviews. (2015) (0)
Enhanced hypothalamic-pituitary-adrenal axis activation, 5[alpha]-reductase activity and insulin resistance distinguishes polycystic ovary syndrome from simple obesity (2008) (0)
European Journal of Endocrinology Prize Winner (2009) (0)
Mutant cytochrome b5 causing 46,XY disorder of sex development (DSD) due to apparent CYP17A1 17,20 lyase deficiency (2011) (0)
The role of serum and urinary steroids in the monitoring of adults with congenital adrenal hyperplasia (2009) (0)
Systematic review of behavioural change interventions for the prevention of adrenal crisis in adults with primary adrenal insufficiency - An infographic interpretation (2021) (0)
Development of a liquid chromatography tandem mass spectrometry assay for the profiling of salivary androgens and gestagens (2017) (0)
Early truncation of the human CYP17A1 protein results in severe neonatal adrenal insufficiency (2008) (0)
Subject Index Vol. 68, Suppl. 5, 2007 (2007) (0)
SAT-368 Natural History Of Adrenal Incidentalomas With And Without Mild Autonomous Cortisol Excess; A Systematic Review And Meta-analysis (2019) (0)
Dissecting the androgen excess phenotype of women with idiopathic intracranial hypertension (2017) (0)
Simulation via Instant Messaging - Birmingham Advance helps to narrow the gap of knowledge and expectations between clinicians and women with polycystic ovary syndrome: A SIMBA-PCOS mixed-method study (2022) (0)
Optimizing mineralocorticoid replacement therapy in patients with congenital adrenal hyperplasia and Addison's disease (2019) (0)
Double trouble: pseudo-phaeochromocytoma in a patient with adrenocortical cancer (2014) (0)
University of Birmingham Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA (2018) (0)
MON-447 Impact Of Cortisone And Glucocorticoid Metabolites On Bone Turnover Markers in Male Patients With Hypopituitarism (2019) (0)
A Phase III randomized, controlled trial of a modified-release hydrocortisone formulation in the treatment of classic congenital adrenal hyperplasia (2020) (0)
Reduced 5α-reductase activity in peripheral blood mononuclear cells in polycystic ovarian syndrome a compensatory mechanism for androgen excess? (2007) (0)
PAPSS2 deficiency: a novel monogenic cause of androgen excess (2009) (0)
Simulation via Instant Messaging - Birmingham Advance (SIMBA): Impact of online simulation-based learning on doctors’ confidence in managing cases during the COVID-19 pandemic (2021) (0)
Acute changes in steroid biosynthesis in patients following severe trauma: the golden hour study (2019) (0)
University of Birmingham AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome (2017) (0)
Urine steroid metabolomics as a diagnostic tool for detection of adrenocortical malignancy - a prospective test validation study (2018) (0)
Intelligent Computation meets bio-medical research: recent developments in computational biology (2014) (0)
Inactivating progesterone metabolism in human osteoblasts (2004) (0)
Dehydroepiandrosterone exerts anti-glucocorticoid action on proliferation, differentiation and insulin sensitivity in human preadipocytes (2008) (0)
Predominant activation of 11-oxygenated androgens by peripheral blood mononuclear cells (2020) (0)
University of Birmingham Quantitative brain MRI in congenital adrenal hyperplasia (2018) (0)
Mitotane treatment for metastatic Leydig cell tumour (2015) (0)
Molecular Architecture of Androgen Receptor Pathways Amplifying Glucagon-Like Peptide-1 Insulinotropic Action in Male Pancreatic β-Cells (2022) (0)
The Prevention of Adrenal Crisis in Stress (PACS) study: serum cortisol during elective surgery and acute trauma in comparison to stress dose hydrocortisone in adrenal insufficiency (2014) (0)
Reduced androgen activation in peripheral blood mononuclear cells in polycystic ovarian syndrome – a compensatory mechanism for hyperandrogenaemia? (2007) (0)
Improved biochemical control with modified-release hydrocortisone overturns the impaired fludrocortisone effect in salt-wasting CAH patients (2022) (0)
Cortisol, DHEAS and immunesenescence (2011) (0)
AKR1C3-mediated adipose androgen generation drives lipotoxicity in polycystic ovary syndrome (2017) (0)
Visceral fat drives 5[alpha]-reductase activity independent of BMI in women with polycystic ovarian syndrome (2015) (0)
11C-metomidate PET CT versus Adrenal Vein Sampling for diagnosing surgically curable primary aldosteronism: prospective test validation, and impact of somatic genotype and ethnicity on outcomes (2021) (0)
The hitchhiker's guide to the steroid galaxy (2010) (0)
Clinical Endocrinology Trust Lecture (2015) (0)
Ligand Expression Signals Regulate CD 30 Ligand but Not OX 40 Inducer Cells : Evidence That IL-7 − CD 3 + Expressed on Adult but Not Neonatal CD 4 OX 40 Ligand and CD 30 Ligand Are Erlandsson (2005) (0)
Synergistic Effects of Aging and Stress on Neutrophil Function (2019) (0)
Steroid metabolomics: a rapid computational approach for accurate differentiation of inborn disorders of steroidogenesis (2019) (0)
Chronic inflammation regulates androgen metabolism and exposure in Macrophages (2021) (0)
Identification of Novel Central Nervous System Imaging Biomarkers Associated with Cognitive Abnormalities in Patients with Congenital Adrenal Hyperplasia (2016) (0)
Adrenal Incidentaloma (2021) (0)
Best Practice & Research Clinical Endocrinology & Metabolism (2009) (0)
Management of Adrenal Insufficiency (2021) (0)
Phaeochromocytomas Most Commonly Present As Adrenal Incidentalomas - A Large Tertiary Centre Experience (2022) (0)
The biochemical investigation of PCOS: a UK wide survey of laboratory practice (2022) (0)
Simulation via Instant Messaging Birmingham Advance (SIMBA) model helps improve clinicians confidence to manage various endocrine conditions during the COVID-19 pandemic (2021) (0)
MON-203 Local Activation of 11-Oxygenated Androgens by AKR1C3 Is the Predominant Source of Androgens in Human Female Adipose Tissue (2019) (0)
Jumping the gun: an audit of adrenal biopsies in a tertiary referral centre (2014) (0)
A novel approach to serum multi-steroid profiling using ultra high-performance liquid chromatography-tandem mass spectrometry with post column infusion ammonium fluoride (2021) (0)
ADRENAL-HYPERTENSION Clinical Factors Associated with Insulin Secretion and Sensitivity in Patients with Primary Aldosteronism (2020) (0)
Increased anxiety, depression and body dysmorphia in women with polycystic ovary syndrome: Results from blue morpho survey (2021) (0)
Modified release hydrocortisone capsules (MRHC, Efmody) improve control of congenital adrenal hyperplasia (CAH) on a lower glucocorticoid dose than standard treatment (2022) (0)
Pheochromocytoma is Characterized By Catecholamine Myocarditis, Focal and Diffuse Fibrosis, and Persistent Subclinical Systolic and Diastolic Dysfunction (2016) (0)
A novel entity of isolated adrenal insufficiency caused by partial inactivation of P450 side-chain cleavage (CYP11A1) enzyme (2011) (0)
No evidence for hepatic conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA – in vivo and in vitro studies (2004) (0)
Chronocort[reg], a multiparticulate modified release hydrocortisone formulation, shows dose linearity and twice daily dosing provides physiological cortisol exposure (2013) (0)
Distinct patterns of glucocorticoid metabolism in patients with HNF1A-MODY have the potential to confer a beneficial metabolic phenotype (2017) (0)
Clinical outcomes in adrenocortical carcinoma: evaluation of single and combined prognostic markers in a UK single centre cohort (2019) (0)
Using corticosteroids in intensive care. (2006) (0)
Alternative pathway synthesis dominates androgen production in patients with congenital adrenal hyperplasia and is decreased by Chronocort ® more than by conventional glucocorticoid therapy (2015) (0)
MAPPING THE STEROID METABOLOME IN INBORN STEROIDOGENIC DISORDERS: PERFORMANCE OF A NOVEL COMPUTATIONAL APPROACH IN COMPARISON TO CONVENTIONAL GC-MS ANALYSIS (2017) (0)
Mining the steroid metabolome in adrenal hormone excess (2015) (0)
Sex-specific risk of obesity and cardiometabolic disease in low- and middle-income countries (LMICs): a meta-analysis in 681929 individuals (2021) (0)
Adipose tissue-specific androgen generation fuels an adverse metabolic phenotype in patients with polycystic ovary syndrome (2015) (0)
Blue Morpho: An international survey investigating differences in emotional and psychosexual wellbeing by ethnicity and birthplace in women with polycystic ovary syndrome (2022) (0)
Post-operative haemodynamic instability after adrenalectomy for phaeochromocytoma: is routine intensive care admission necessary? (2018) (0)
24-hour urinary steroid metabolites as predictors of response to chemotherapy in metastatic adrenocortical carcinoma (mACC). (2014) (0)
Referees (2008) (0)
Breaking the habit. (2004) (0)
EU-Study: DSD-LIFE (2015) (0)
Autophagy controls the homeostatic environment in the male accessory organs which is essential for fertility (2019) (0)

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