William C. Knowler
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American diabetes researcher
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Medical Philosophy
William C. Knowler's Degrees
- PhD Epidemiology University of California, Berkeley
- Masters Epidemiology University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)William C. Knowler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. (2002) (17532)
- Report of the expert committee on the diagnosis and classification of diabetes mellitus. (1999) (11399)
- Follow-up report on the diagnosis of diabetes mellitus. (2003) (3690)
- International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes (2009) (2534)
- 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. (2009) (2301)
- Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. (1993) (1558)
- Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. (2013) (1520)
- Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes (2007) (1502)
- Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes (2011) (1360)
- Reduced rate of energy expenditure as a risk factor for body-weight gain. (1988) (1191)
- Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. (2000) (1150)
- Prevalence of Diabetes and Impaired Glucose Tolerance and Plasma Glucose Levels in U.S. Population Aged 20–74 Yr (1987) (1148)
- Adiponectin and development of type 2 diabetes in the Pima Indian population (2002) (1138)
- Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. (2011) (841)
- TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. (2006) (796)
- Using the ADAP Learning Algorithm to Forecast the Onset of Diabetes Mellitus (1988) (777)
- Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. (1990) (741)
- Development of Questionnaire to Examine Relationship of Physical Activity and Diabetes in Pima Indians (1990) (740)
- Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? (1994) (737)
- Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. (2003) (683)
- Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus. (1988) (677)
- Predictors of Progression From Impaired Glucose Tolerance to NIDDM: An Analysis of Six Prospective Studies (1997) (658)
- Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota. (1978) (650)
- Severe Periodontitis and Risk for Poor Glycemic Control in Patients with Non-Insulin-Dependent Diabetes Mellitus. (1996) (632)
- Diabetes incidence in Pima indians: contributions of obesity and parental diabetes. (1981) (617)
- MYH9 is associated with nondiabetic end-stage renal disease in African Americans (2008) (614)
- Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis. (1990) (612)
- Components of the "metabolic syndrome" and incidence of type 2 diabetes. (2002) (611)
- The 1997 American Diabetes Association and 1999 World Health Organization criteria for hyperglycemia in the diagnosis and prediction of diabetes. (2000) (554)
- Comparison of tests for glycated haemoglobin and fasting and two hour plasma glucose concentrations as diagnostic methods for diabetes (1994) (540)
- Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy. (1983) (522)
- Congenital Susceptibility to NIDDM: Role of Intrauterine Environment (1988) (520)
- Native American mitochondrial DNA analysis indicates that the Amerind and the Nadene populations were founded by two independent migrations. (1992) (498)
- The natural history of impaired glucose tolerance in the Pima Indians. (1988) (488)
- Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies. (2000) (473)
- Long-term Effects of Lifestyle Intervention or Metformin on Diabetes Development and Microvascular Complications: the DPP Outcomes Study (2015) (455)
- Childhood obesity, other cardiovascular risk factors, and premature death. (2010) (454)
- Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. (2005) (453)
- Periodontal disease and mortality in type 2 diabetes. (2005) (450)
- Racial differences in the relation between blood pressure and insulin resistance. (1991) (442)
- Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. Diabetic Renal Disease Study Group. (1996) (442)
- Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. (2005) (425)
- Increasing prevalence of Type II diabetes in American Indian children (1998) (421)
- Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. (1998) (409)
- Periodontal Disease and NIDDM in Pima Indians (1990) (405)
- Gm3;5,13,14 and type 2 diabetes mellitus: an association in American Indians with genetic admixture. (1988) (404)
- Type 2 diabetes mellitus and periodontal disease. (1990) (390)
- An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. (1995) (380)
- Amerindian mitochondrial DNAs have rare Asian mutations at high frequencies, suggesting they derived from four primary maternal lineages. (1990) (378)
- Increased incidence of retinopathy in diabetics with elevated blood pressure. A six-year follow-up study in Pima Indians. (1980) (375)
- Vitamin D Supplementation and Prevention of Type 2 Diabetes. (2019) (366)
- Long-Term Safety, Tolerability, and Weight Loss Associated With Metformin in the Diabetes Prevention Program Outcomes Study (2012) (345)
- Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima Diabetes Genes Group. (1998) (339)
- Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. (2003) (339)
- Breastfeeding and incidence of non-insulin-dependent diabetes mellitus in Pima Indians (1997) (336)
- Insulin resistance associated with lower rates of weight gain in Pima Indians. (1991) (332)
- The effect of lifestyle intervention and metformin on preventing or delaying diabetes among women with and without gestational diabetes: the Diabetes Prevention Program outcomes study 10-year follow-up. (2015) (326)
- Non-insulin dependent diabetes mellitus and alveolar bone loss progression over 2 years. (1998) (322)
- Obesity in the Pima Indians: its magnitude and relationship with diabetes. (1991) (318)
- In Vivo Insulin Action Is Familial Characteristic in Nondiabetic Pima Indians (1987) (317)
- Prevalence of Diabetes in Mexican Americans, Cubans, and Puerto Ricans From the Hispanic Health and Nutrition Examination Survey, 1982–1984 (1991) (316)
- The prevalence of retinopathy in impaired glucose tolerance and recent‐onset diabetes in the Diabetes Prevention Program (2007) (314)
- Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study. (2016) (312)
- Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial. (2016) (308)
- SEQUENTIAL CHANGES IN SERUM INSULIN CONCENTRATION DURING DEVELOPMENT OF NON-INSULIN-DEPENDENT DIABETES (1989) (307)
- Gestational Diabetes: Infant and Maternal Complications of Pregnancy in Relation to Third-Trimester Glucose Tolerance in the Pima Indians (1980) (301)
- A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. (2000) (301)
- Diabetes and Obesity in the Offspring of Pima Indian Women With Diabetes During Pregnancy (1993) (293)
- Effect of diabetes in pregnancy on offspring: follow-up research in the Pima Indians. (2000) (290)
- Effect of Periodontitis on Overt Nephropathy and End-Stage Renal Disease in Type 2 Diabetes (2007) (289)
- Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
- Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians. (2006) (280)
- Birth weight, type 2 diabetes, and insulin resistance in Pima Indian children and young adults. (1999) (275)
- Familial predisposition to renal disease in two generations of Pima Indians with Type 2 (non-insulin-dependent) diabetes mellitus (1990) (270)
- Physical activity, obesity, and the incidence of type 2 diabetes in a high-risk population. (2003) (268)
- Medial arterial calcification and its association with mortality and complications of diabetes (1988) (263)
- A two-step model for development of non-insulin-dependent diabetes. (1991) (259)
- Lower-Extremity Amputations in NIDDM: 12-Yr Follow-Up Study in Pima Indians (1988) (246)
- Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program (2010) (244)
- Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring. (2006) (237)
- Gestational Diabetes Mellitus and Impaired Glucose Tolerance During Pregnancy: Long-Term Effects on Obesity and Glucose Tolerance in the Offspring (1985) (235)
- Familial dependence of the resting metabolic rate. (1986) (232)
- Long-term effects of the intrauterine environment, birth weight, and breast-feeding in Pima Indians. (1998) (226)
- Low incidence of fatal coronary heart disease in Pima Indians despite high prevalence of non-insulin-dependent diabetes. (1990) (212)
- Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. (2014) (211)
- Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus. (1990) (210)
- Plasma glucose and prediction of microvascular disease and mortality: evaluation of 1997 American Diabetes Association and 1999 World Health Organization criteria for diagnosis of diabetes. (2000) (208)
- Abnormal Glucose Tolerance During Pregnancy in Pima Indian Women: Long-Term Effects on Offspring (1991) (205)
- Type 2 diabetes and low birth weight: the role of paternal inheritance in the association of low birth weight and diabetes. (2000) (199)
- Identification of PVT1 as a Candidate Gene for End-Stage Renal Disease in Type 2 Diabetes Using a Pooling-Based Genome-Wide Single Nucleotide Polymorphism Association Study (2007) (197)
- Effectiveness of Lifestyle Interventions for Individuals With Severe Obesity and Type 2 Diabetes (2011) (195)
- Diabetes Mellitus and Its Vascular Complications in Japanese Migrants on the Island of Hawaii (1979) (192)
- Visual lung-sound characterization by time-expanded wave-form analysis. (1977) (189)
- Duration of Obesity Increases the Incidence of NIDDM (1992) (189)
- Dramatic founder effects in Amerindian mitochondrial DNAs. (1985) (185)
- The interleukin-6 (−174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians (2003) (185)
- Effect of Proteinuria on Mortality in NIDDM (1988) (184)
- Rheumatoid arthritis and mortality. A longitudinal study in Pima Indians. (1993) (178)
- Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians. (2003) (175)
- Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study. (2000) (174)
- Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program (2011) (173)
- The Diabetes Prevention Program: recruitment methods and results. (2002) (172)
- Relationship between insulin-mediated glucose disposal and lipid metabolism in man. (1985) (171)
- Obesity in Offspring of Diabetic Pima Indian Women Despite Normal Birth Weight (1987) (171)
- DEVELOPMENT OF RETINOPATHY AND PROTEINURIA IN RELATION TO PLASMA-GLUCOSE CONCENTRATIONS IN PIMA INDIANS (1980) (170)
- High incidence and prevalence of rheumatoid arthritis in Pima Indians. (1989) (169)
- Childhood Predictors of Young-Onset Type 2 Diabetes (2007) (168)
- Heritability of the severity of diabetic retinopathy: the FIND-Eye study. (2008) (163)
- Impact of Intensive Lifestyle Intervention on Depression and Health-Related Quality of Life in Type 2 Diabetes: The Look AHEAD Trial (2014) (163)
- The incidence of rheumatoid arthritis is predicted by rheumatoid factor titer in a longitudinal population study. (1988) (161)
- Regression From Pre-Diabetes to Normal Glucose Regulation in the Diabetes Prevention Program (2009) (157)
- The prevention of type 2 diabetes (2008) (155)
- Preventing Non-Insulin-Dependent Diabetes (1995) (154)
- Linkage of Chromosomal Markers on 4q With a Putative Gene Determining Maximal Insulin Action in Pima Indians (1993) (153)
- GM allotypes in Native Americans: evidence for three distinct migrations across the Bering land bridge. (1985) (152)
- Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24. (2003) (151)
- Association Analysis of Variation in/Near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B With Type 2 Diabetes and Related Quantitative Traits in Pima Indians (2009) (150)
- International Criteria for the Diagnosis of Diabetes and Impaired Glucose Tolerance (1985) (149)
- Impact of an Intensive Lifestyle Intervention on Use and Cost of Medical Services Among Overweight and Obese Adults With Type 2 Diabetes: The Action for Health in Diabetes (2014) (149)
- Incidence of proteinuria in type 2 diabetes mellitus in the Pima Indians. (1989) (149)
- Genome-Wide Scans for Diabetic Nephropathy and Albuminuria in Multiethnic Populations (2007) (148)
- Diabetes mellitus in the Pima Indians: genetic and evolutionary considerations. (1983) (147)
- Polymorphism in the 5' flanking region of the human insulin gene: a genetic marker for non-insulin-dependent diabetes. (1983) (147)
- Distribution of In Vivo Insulin Action in Pima Indians as Mixture of Three Normal Distributions (1989) (142)
- Primary prevention of non-insulin-dependent diabetes mellitus. (1992) (136)
- Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND) (2015) (135)
- A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping. (2007) (134)
- Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes. (2004) (134)
- Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. (2007) (133)
- Ethnic-difference markers for use in mapping by admixture linkage disequilibrium. (2002) (132)
- Prevalence of gallstone disease in Hispanic populations in the United States. (1989) (131)
- A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. (2010) (130)
- Glomerular function in Pima Indians with noninsulin-dependent diabetes mellitus of recent onset. (1991) (129)
- Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes (2003) (128)
- Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study (2017) (124)
- Incidence of end-stage renal disease in Type 2 (non-insulin-dependent) diabetes mellitus in pima indians (1988) (123)
- Assessment of risk of overt nephropathy in diabetic patients from albumin excretion in untimed urine specimens. (1991) (121)
- Type 2 Diabetes–Associated Missense Polymorphisms KCNJ11 E23K and ABCC8 A1369S Influence Progression to Diabetes and Response to Interventions in the Diabetes Prevention Program (2007) (120)
- Randomized clinical trial of lifestyle interventions in Pima Indians: a pilot study (1998) (120)
- Decreasing incidence and prevalence of rheumatoid arthritis in Pima Indians over a twenty-five-year period. (1994) (119)
- Incidence of retinopathy and nephropathy in youth-onset compared with adult-onset type 2 diabetes. (2003) (119)
- Determinants of Diabetes Mellitus in the Pima Indians (1993) (118)
- Stabilization of glucose in blood samples: why it matters. (2009) (116)
- Relationship of Glycosylated Hemoglobin to Oral Glucose Tolerance: Implications for Diabetes Screening (1988) (112)
- The long-term effectiveness of a lifestyle intervention in severely obese individuals. (2013) (111)
- Mexican American ancestry-informative markers: examination of population structure and marker characteristics in European Americans, Mexican Americans, Amerindians and Asians (2004) (110)
- Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of type 2 diabetes and BMI in Pima Indians. (2001) (110)
- Genome-wide linkage analysis of serum adiponectin in the Pima Indian population. (2003) (108)
- Genome-Wide Linkage Analyses to Identify Loci for Diabetic Retinopathy (2007) (108)
- Comparison of screening tests for non-insulin-dependent diabetes mellitus. (1993) (106)
- Rate of Weight Gain, Weight Fluctuation, and Incidence of NIDDM (1995) (106)
- Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program (2008) (106)
- Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program (2012) (105)
- Diagnosing diabetes mellitus – do we need new criteria? (1997) (104)
- Insulin and Hypertension: Relationship to Obesity and Glucose Intolerance in Pima Indians (1990) (102)
- Risk factors for gallstone disease in the Hispanic populations of the United States. (1990) (101)
- Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes (2014) (101)
- A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array (2007) (100)
- Lifestyle interventions limit gestational weight gain in women with overweight or obesity: LIFE-Moms prospective meta-analysis (2018) (100)
- The association of physical activity with obesity, fat distribution and glucose intolerance in Pima Indians (1993) (99)
- Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study (2010) (98)
- Plasma and lipoprotein cholesterol and triglyceride concentrations in the Pima Indians: distributions differing from those of Caucasians. (1983) (98)
- Resistance Versus Aerobic Exercise Acute effects on glycemia in type 1 diabetes (2012) (97)
- The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. (2005) (96)
- Incidence and Determinants of Elevated Urinary Albumin Excretion in Pima Indians With NIDDM (1995) (94)
- Plasma and Lipoprotein Cholesterol and Triglyceride in the Pima Indian Population: Comparison of Diabetics and Nondiabetics (1984) (92)
- Segregation analysis of diabetic nephropathy in Pima Indians. (2000) (92)
- Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study (2020) (91)
- Proliferative Retinopathy in NIDDM: Incidence and Risk Factors in Pima Indians (1989) (90)
- Perinatal characteristics and risk of rheumatoid arthritis (2003) (90)
- Association of physical activity and serum insulin concentrations in two populations at high risk for type 2 diabetes but differing by BMI. (2001) (90)
- Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes (2013) (90)
- Survey of the diet of Pima Indians using quantitative food frequency assessment and 24-hour recall. Diabetic Renal Disease Study. (1996) (89)
- TCF7L2 Is Not a Major Susceptibility Gene for Type 2 Diabetes in Pima Indians (2007) (88)
- Habitual physical activity in children: the role of genes and the environment. (2005) (87)
- Diabetic retinopathy assessed by fundus photography in Pima Indians with impaired glucose tolerance and NIDDM (1997) (87)
- Glucose, insulin concentrations and obesity in childhood and adolescence as predictors of NIDDM (1994) (87)
- Factors Associated With Diabetes Onset During Metformin Versus Placebo Therapy in the Diabetes Prevention Program (2007) (87)
- Optimizing a Proteomics Platform for Urine Biomarker Discovery* (2010) (84)
- A Locus Influencing Total Serum Cholesterol on Chromosome 19p: Results From an Autosomal Genomic Scan of Serum Lipid Concentrations in Pima Indians (2000) (84)
- Progression to Type 2 Diabetes Characterized by Moderate Then Rapid Glucose Increases (2007) (82)
- Insulin Treatment, Endogenous Insulin Concentration, and ECG Abnormalities in Diabetic Pima Indians: Cross-Sectional and Prospective Analyses (1992) (82)
- Relationship between inpatient hyperglycemia and insulin treatment after kidney transplantation and future new onset diabetes mellitus. (2010) (82)
- Diabetes and oral disease: implications for health professionals (2012) (81)
- COVID-19 in People With Diabetes: Urgently Needed Lessons From Early Reports (2020) (80)
- Association of Weight Loss Maintenance and Weight Regain on 4-Year Changes in CVD Risk Factors: the Action for Health in Diabetes (Look AHEAD) Clinical Trial (2016) (80)
- Islet amyloid polypeptide in diabetic and non-diabetic Pima Indians (1990) (80)
- Comparison of World Health Organization and National Diabetes Data Group Procedures to Detect Abnormalities of Glucose Tolerance During Pregnancy (1994) (79)
- Albuminuria in Type 2 (non-insulin-dependent) diabetes mellitus and impaired glucose tolerance in Pima Indians (1989) (79)
- Interaction Between an 11&bgr;HSD1 Gene Variant and Birth Era Modifies the Risk of Hypertension in Pima Indians (2004) (78)
- Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major-gene effect. (1995) (78)
- Early renal function decline in type 2 diabetes. (2012) (77)
- Diabetic Kidney Disease in Pima Indians (1993) (77)
- HbA1c as a Predictor of Diabetes and as an Outcome in the Diabetes Prevention Program: A Randomized Clinical Trial (2014) (77)
- Gamma globulin levels predict type 2 diabetes in the Pima Indian population. (2001) (75)
- Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial (2014) (75)
- The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program (2012) (74)
- Impact of NIDDM on Mortality and Causes of Death in Pima Indians (1992) (74)
- Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program (2008) (73)
- Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program (2009) (73)
- Screening for NIDDM: Opportunities for detection, treatment, and prevention (1994) (73)
- The Pro12Ala variant at the peroxisome proliferator-activated receptor γ gene and change in obesity-related traits in the Diabetes Prevention Program (2007) (72)
- Can New-Onset Diabetes After Kidney Transplant Be Prevented? (2013) (72)
- Coffee consumption and the incidence of type 2 diabetes. (2003) (72)
- Mortality as a function of obesity and diabetes mellitus. (1982) (71)
- Pretransplant Risk Score for New-Onset Diabetes After Kidney Transplantation (2011) (71)
- Low plasma adiponectin concentrations do not predict weight gain in humans. (2002) (71)
- Longitudinal studies of incidence and progression of diabetic retinopathy assessed by retinal photography in pima indians. (2003) (70)
- Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians. (2001) (70)
- Increased In Vivo Insulin Resistance in Nondiabetic Pima Indians Compared with Caucasians (1982) (69)
- Structural Predictors of Loss of Renal Function in American Indians with Type 2 Diabetes. (2016) (69)
- Obesity in Pima Indians: large increases among post-World War II birth cohorts. (1993) (69)
- Antidepressant Medicine Use and Risk of Developing Diabetes During the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study (2010) (69)
- DRD2 haplotypes containing the TaqI A1 allele: implications for alcoholism research. (1996) (68)
- Hip osteoarthritis prevalence estimates by three radiographic scoring systems. (1998) (68)
- Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study (2019) (67)
- The diabetes prevention program and its global implications. (2003) (67)
- First versus repeat treatment with a lifestyle intervention program: attendance and weight loss outcomes (2008) (67)
- Progression of overt nephropathy in non-insulin-dependent diabetes. (1995) (66)
- Insulinemia in Children at Low and High Risk of NIDDM (1993) (65)
- The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population. (2003) (65)
- HbA1c and the Prediction of Type 2 Diabetes in Children and Adults (2016) (65)
- Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials (2015) (64)
- Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death. (2011) (64)
- Glucose tolerance and mortality, including a substudy of tolbutamide treatment (1997) (64)
- A Genome-Wide Association Study in American Indians Implicates DNER as a Susceptibility Locus for Type 2 Diabetes (2013) (63)
- Development of lithogenic bile during puberty in Pima indians. (1979) (63)
- Depression symptoms and antidepressant medicine use in Diabetes Prevention Program participants. (2005) (62)
- Meta-analysis reveals association between most common class II haplotype in full-heritage Native Americans and rheumatoid arthritis. (1995) (62)
- Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program (2008) (61)
- Genome-Wide Scan for Estimated Glomerular Filtration Rate in Multi-Ethnic Diabetic Populations (2008) (61)
- Differential methylation of genes in individuals exposed to maternal diabetes in utero (2017) (60)
- Cardiovascular disease risk factors, depression symptoms and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes (2010) (60)
- SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians. (2011) (60)
- Diabetic Retinopathy, Promoter (4G/5G) Polymorphism of PAI-1 Gene, and PAI-1 Activity in Pima Indians With Type 2 Diabetes (1997) (60)
- Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians. (2005) (59)
- Activity patterns of obese adults with type 2 diabetes in the look AHEAD study. (2010) (59)
- Lower Metabolic Rate in Individuals Heterozygous for Either a Frameshift or a Functional Missense MC4R Variant (2008) (59)
- The U-shaped association between body mass index and mortality: relationship with weight gain in a Native American population. (1995) (58)
- Absence of Linkage of Obesity and Energy Metabolism to Markers Flanking Homologues of Rodent Obesity Genes in Pima Indians (1996) (58)
- Potential epigenetic dysregulation of genes associated with MODY and type 2 diabetes in humans exposed to a diabetic intrauterine environment: an analysis of genome-wide DNA methylation. (2014) (57)
- Effects of Metformin and Weight Loss on Serum Alanine Aminotransferase Activity in the Diabetes Prevention Program (2010) (57)
- Comparison of Body Size Measurements as Predictors of NIDDM in Pima Indians (1995) (57)
- Early growth in offspring of diabetic mothers. (2005) (57)
- Alcohol consumption predicts hypertension but not diabetes. (2004) (57)
- Four-Year Change in Cardiorespiratory Fitness and Influence on Glycemic Control in Adults With Type 2 Diabetes in a Randomized Trial (2013) (56)
- Arsenic exposure and incidence of type 2 diabetes in Southwestern American Indians. (2013) (56)
- Evidence for Linkage Between a Region on Chromosome 1p and the Acute Insulin Response in Pima Indians (1995) (56)
- Diabetes Mellitus in Hopi and Navajo Indians: Prevalence of Microvascular Complications (1983) (56)
- Transient impaired glucose tolerance in Pima Indians: is it important? (1988) (56)
- Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians. (1998) (56)
- Strong Parent-of-Origin Effects in the Association of KCNQ1 Variants With Type 2 Diabetes in American Indians (2013) (56)
- Regional differences in albuminuria among American Indians: an epidemic of renal disease. (1996) (55)
- Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes (2016) (54)
- Depression, diabetes, and glycemic control in an American Indian community. (2008) (54)
- Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment (2017) (54)
- Family and genetic studies of indices of insulin sensitivity and insulin secretion in Pima Indians † ‡ (2001) (54)
- Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians (2011) (53)
- Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q (2006) (52)
- Linkage Analysis of Acute Insulin Secretion With GLUT2 and Glucokinase in Pima Indians and the Identification of a Missense Mutation in GLUT2 (1994) (52)
- The Relationship of Menstrual Irregularity to Type 2 Diabetes in Pima Indian Women (1998) (52)
- The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program. (2009) (52)
- Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2‐h plasma glucose concentrations (2007) (51)
- Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of birth weight (2002) (51)
- Tumor necrosis factor receptors 1 and 2 are associated with early glomerular lesions in type 2 diabetes (2015) (51)
- Common Variation in SIM1 Is Reproducibly Associated With BMI in Pi ma Indians (2009) (50)
- Genomewide Linkage Scan for Diabetic Renal Failure and Albuminuria: The FIND Study (2011) (49)
- Albuminuria within the "normal" range and risk of cardiovascular disease and death in American Indians: the Strong Heart Study. (2007) (49)
- Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study (2017) (49)
- Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program (2012) (47)
- Predictive power of sequential measures of albuminuria for progression to ESRD or death in Pima Indians with type 2 diabetes. (2008) (47)
- Studies of the etiology of obesity in Pima Indians. (1991) (46)
- ELMO1 variants and susceptibility to diabetic nephropathy in American Indians. (2010) (46)
- Pre-diabetic blood pressure predicts urinary albumin excretion after the onset of Type 2 (non-insulin-dependent) diabetes mellitus in Pima Indians (1993) (46)
- The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial (2017) (46)
- Kidney Diseases in Diabetes (1996) (45)
- The magnitude and origin of European-American admixture in the Gila River Indian Community of Arizona: a union of genetics and demography. (1992) (45)
- Strategies to identify adults at high risk for type 2 diabetes: the Diabetes Prevention Program. (2005) (45)
- The Association of Arsenic Exposure and Metabolism With Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study (2016) (44)
- Evaluation of A2BP1 as an Obesity Gene (2010) (44)
- The angiotensin-I converting enzyme (ACE) gene I/D polymorphism and ACE levels in Pima Indians. (1996) (44)
- A High-Carbohydrate, High-Fiber, Low-Fat Diet Results in Weight Loss among Adults at High Risk of Type 2 Diabetes. (2017) (44)
- The association of plasma fibrinogen concentration with diabetic microvascular complications in young adults with early-onset of type 2 diabetes. (2008) (43)
- Genetics of diabetic nephropathy in the pima indians (2001) (43)
- Early excess weight gain of children in the Pima Indian population. (2002) (43)
- A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes (2017) (43)
- Comparison of serum cystatin C, serum creatinine, measured GFR, and estimated GFR to assess the risk of kidney failure in American Indians with diabetic nephropathy. (2013) (43)
- Bene fi ts of ModestWeight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes (2011) (43)
- Familial and metabolic factors related to blood pressure in Pima Indian children. (1994) (42)
- Describing patterns of weight changes using principal components analysis: results from the Action for Health in Diabetes (Look AHEAD) research group. (2009) (42)
- Racial/ethnic differences in the burden of type 2 diabetes over the life course: a focus on the USA and India (2019) (42)
- Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS) (2019) (42)
- Absence of glutamic acid decarboxylase antibodies in Pima Indian children with diabetes mellitus (1999) (42)
- Factors Affecting the Decline in Incidence of Diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS) (2014) (42)
- FTO predicts weight regain in the Look AHEAD Clinical Trial (2013) (42)
- Determinants of end-stage renal disease in Pima Indians with Type 2 (non-insulin-dependent) diabetes mellitus and proteinuria (1993) (41)
- Polymorphism in the 5' flanking region of the human insulin gene. Relationships with noninsulin-dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians. (1984) (41)
- Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation (2017) (41)
- Early detection and intervention in diabetes mellitus: is it effective? (1984) (41)
- Diabetes Prevention Program (DPP) (2020) (41)
- Does diabetes prevention translate into reduced long-term vascular complications of diabetes? (2019) (40)
- Increased Mortality with Gallstone Disease: Results of a 20-Year Population-Based Survey in Pima Indians (1993) (39)
- Meprin β metalloprotease gene polymorphisms associated with diabetic nephropathy in the Pima Indians (2005) (39)
- Glycated haemoglobin, plasma glucose and diabetic retinopathy: cross-sectional and prospective analyses (1993) (38)
- ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes (2015) (38)
- Self-reported diabetes in Mexican Americans: HHANES 1982-84. (1989) (38)
- Plasma lipoproteins and incidence of non-insulin-dependent diabetes mellitus in Pima Indians: protective effect of HDL cholesterol in women. (1997) (37)
- Islet cell antibodies and diabetes mellitus in Pima Indians (1979) (37)
- First versus repeat treatment with a lifestyle intervention program: attendance and weight loss outcomes (2009) (36)
- Variation at the Melanocortin 4 Receptor gene and response to weight-loss interventions in the Diabetes Prevention Program (2013) (36)
- Cytosine methylation predicts renal function decline in American Indians. (2018) (36)
- An epidemiologic study of trends in prevalence of rheumatoid factor seropositivity in Pima Indians: evidence of a decline due to both secular and birth-cohort influences. (2002) (36)
- Promoter (4G/5G) plasminogen activator inhibitor-1 genotype in Pima Indians: relationship to plasminogen activator inhibitor-1 levels and features of the insulin resistance syndrome (1996) (36)
- A cross-sectional and longitudinal comparison of the Rome criteria for active rheumatoid arthritis (equivalent to the American College of Rheumatology 1958 criteria) and the American College of Rheumatology 1987 criteria for rheumatoid arthritis. (1994) (35)
- Glycated haemoglobin predicts progression to diabetes mellitus in Pima Indians with impaired glucose tolerance (1994) (35)
- Incidence, prevalence and risk factors for non-insulin-dependent diabetes mellitus. (1988) (35)
- Value of Urinary Albumin-to-Creatinine Ratio as a Predictor of Type 2 Diabetes in Pre-Diabetic Individuals (2008) (35)
- The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals (2008) (35)
- Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program (2012) (34)
- Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes (2007) (34)
- One-hour and two-hour postload plasma glucose concentrations are comparable predictors of type 2 diabetes mellitus in Southwestern Native Americans (2017) (34)
- Associations between persistent organic pollutants, type 2 diabetes, diabetic nephropathy and mortality (2017) (34)
- HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion (2011) (33)
- Exploring residual risk for diabetes and microvascular disease in the Diabetes Prevention Program Outcomes Study (DPPOS) (2017) (33)
- Rheumatoid arthritis in the Pima Indians: the intersection of epidemiologic, demographic, and genealogic data. (1998) (33)
- Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians (2010) (33)
- Four-Year Analysis of Cardiovascular Disease Risk Factors, Depression Symptoms, and Antidepressant Medicine Use in the Look AHEAD (Action for Health in Diabetes) Clinical Trial of Weight Loss in Diabetes (2013) (33)
- Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program (2012) (33)
- Consent for genetics studies among clinical trial participants: findings from Action for Health in Diabetes (Look AHEAD) (2006) (32)
- Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project (2015) (32)
- Which Test for Diagnosing Diabetes? (1995) (32)
- Gravidity, obesity, and non-insulin-dependent diabetes among Pima Indian women. (1994) (32)
- Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study (2018) (31)
- Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial (2020) (31)
- Greater Impact of Melanocortin-4 Receptor De fi ciency on Rates of Growth and Risk of Type 2 Diabetes Mellitus During Childhood Compared With Adulthood in Pima Indians (2011) (31)
- Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants (2015) (31)
- Whole Exome Sequencing Identifies Variation in CYB5A and RNF10 Associated with Adiposity and Type 2 Diabetes (2013) (31)
- HDL cholesterol subfractions and risk of developing type 2 diabetes among Pima Indians. (1999) (31)
- Severe periodontitis and risk for poor glycemic control in patients with non-insulin-dependent diabetes mellitus. (1996) (30)
- Low prevalences of chronic widespread pain and shoulder disorders among the Pima Indians. (1996) (30)
- Hematocrit and the incidence of type 2 diabetes in the pima indians. (2004) (30)
- Gm 3;5,13,14 and stated-admixture: independent estimates of admixture in American Indians. (1986) (30)
- Changing glomerular filtration with progression from impaired glucose tolerance to Type II diabetes mellitus (Short Communications) (1999) (30)
- Reliability of urinary albumin, total protein, and creatinine assays after prolonged storage: the Family Investigation of Nephropathy and Diabetes. (2007) (30)
- A Genome‐Wide Association Study of BMI in American Indians (2011) (29)
- Variants in the Cav2.3 (α1E) Subunit of Voltage-Activated Ca2+ Channels Are Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians (2007) (28)
- TCF7L2 Polymorphism, Weight Loss and Proinsulin∶Insulin Ratio in the Diabetes Prevention Program (2011) (28)
- A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians (2017) (28)
- Diabetes and atherosclerosis in the Pima Indians. (1982) (28)
- Correlation Between Baseline GFR and Subsequent Change in GFR in Norwegian Adults Without Diabetes and in Pima Indians. (2019) (28)
- Depression as a Predictor of Weight Regain Among Successful Weight Losers in the Diabetes Prevention Program (2013) (28)
- Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure (2014) (27)
- Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study (2012) (27)
- Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program (2014) (27)
- Incidence of cataract extraction in Pima Indians. Diabetes as a risk factor. (1985) (27)
- Depression, diabetes, and glycemic control in Pima Indians. (2004) (27)
- The Impact of Physical Activity on the Prevention of Type 2 Diabetes: Evidence and Lessons Learned From the Diabetes Prevention Program, a Long-Standing Clinical Trial Incorporating Subjective and Objective Activity Measures. (2020) (27)
- Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus. (2015) (27)
- Predictive Value of Albuminuria in American Indian Youth With or Without Type 2 Diabetes (2010) (27)
- A Two-Step Strategy for Identification of High-Risk Subjects for a Clinical Trial of Prevention of NIDDM (1996) (26)
- Human Cardiovascular Disease IBC Chip-Wide Association with Weight Loss and Weight Regain in the Look AHEAD Trial (2013) (26)
- Do Genetic Modifiers of High-Density Lipoprotein Cholesterol and Triglyceride Levels Also Modify Their Response to a Lifestyle Intervention in the Setting of Obesity and Type-2 Diabetes Mellitus?: The Action for Health in Diabetes (Look AHEAD) Study (2013) (26)
- Familial Relationships Between Obesity and NIDDM (1995) (26)
- Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians (1996) (26)
- MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation (2013) (26)
- Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children (2014) (26)
- Effect of severe obesity in childhood and adolescence on risk of type 2 diabetes in youth and early adulthood in an American Indian population (2018) (25)
- Validation of a Pretransplant Risk Score for New-Onset Diabetes After Kidney Transplantation (2013) (25)
- Diabetic nephropathy in American Indians, with a special emphasis on the pima Indians (2008) (25)
- Genetic Risk of Progression to Type 2 Diabetes and Response to Intensive Lifestyle or Metformin in Prediabetic Women With and Without a History of Gestational Diabetes Mellitus (2014) (25)
- A Genome-Wide Search for Linkage of Estimated Glomerular Filtration Rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND) (2013) (25)
- Variants in the LEPR gene are nominally associated with higher BMI and lower 24 hour energy expenditure in Pima Indians (2012) (25)
- Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study (2021) (24)
- Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study (2022) (24)
- Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes. (2005) (24)
- The Kidney and Hypertension in Diabetes Mellitus (1994) (24)
- Endogenous glucose production, insulin sensitivity, and insulin secretion in normal glucose-tolerant Pima Indians with low birth weight. (2004) (23)
- Change in the Distribution of Albuminuria According to Estimated Glomerular Filtration Rate in Pima Indians With Type 2 Diabetes (2009) (23)
- 674 ASSOCIATION OF PHYSICAL ACTIVITY AND PLASMA INSULIN LEVELS IN A POPULATION AT HIGH RISK FOR NIDDM (1994) (23)
- Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans (2012) (23)
- Variants in ASK1 Are Associated With Skeletal Muscle ASK1 Expression, In Vivo Insulin Resistance, and Type 2 Diabetes in Pima Indians (2010) (23)
- Association of CREBRF variants with obesity and diabetes in Pacific Islanders from Guam and Saipan (2019) (23)
- The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function. (2014) (23)
- Intact Proinsulin, des 31,32 Proinsulin, and Specific Insulin Concentrations Among Nondiabetic and Diabetic Subjects in Populations at Varying Risk of Type 2 Diabetes (1998) (23)
- Homocysteine and vitamin B12 concentrations and mortality rates in type 2 diabetes (2007) (23)
- An explanation for the increase in heart disease mortality rates in diabetic Pima Indians: effect of renal replacement therapy. (2004) (22)
- Population Comparisons of the Frequency of Diabetic Nephropathy (1988) (22)
- Association of variants in the carnosine peptidase 1 gene (CNDP1) with diabetic nephropathy in American Indians. (2011) (21)
- Metabolic Risk Factors and Type 2 Diabetes Incidence in American Indian Children. (2016) (21)
- Idiopathic type 1 diabetes? (2001) (21)
- Relationship of Locus of Control to Physical Activity Among People With and Without Diabetes (1996) (21)
- Long-term Association of Depression Symptoms and Antidepressant Medication Use With Incident Cardiovascular Events in the Look AHEAD (Action for Health in Diabetes) Clinical Trial of Weight Loss in Type 2 Diabetes (2019) (21)
- Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression (2015) (20)
- Confirming glycemic status in the Diabetes Prevention Program: implications for diagnosing diabetes in high risk adults. (2013) (20)
- Cost of intervention delivery in a lifestyle weight loss trial in type 2 diabetes: results from the Look AHEAD clinical trial (2017) (20)
- Diabetic nephropathy: a risk factor for diabetes mellitus in offspring (1995) (20)
- Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program (2019) (19)
- One-year postpartum anthropometric outcomes in mothers and children in the LIFE-Moms lifestyle intervention clinical trials (2019) (19)
- Childhood Predictors of Adult Acute Insulin Response and Insulin Action (2009) (19)
- Functional Variants in MBL2 Are Associated With Type 2 Diabetes and Pre-Diabetes Traits in Pima Indians and the Old Order Amish (2010) (19)
- Impact of intensive lifestyle intervention on preference‐based quality of life in type 2 diabetes: Results from the Look AHEAD trial (2016) (19)
- Brain-Derived Neurotrophic Factor in Human Subjects with Function-Altering Melanocortin-4 Receptor Variants (2013) (19)
- Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial (2015) (19)
- Measurement of glycosylated whole-blood protein for assessing glucose control in diabetes: collection and storage of capillary blood on filter paper. (1985) (19)
- Changes in Albumin Excretion in the Diabetes Prevention Program (2009) (19)
- White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes (2017) (19)
- Serum cholesterol and mortality rates in a Native American population with low cholesterol concentrations: a U-shaped association. (1997) (19)
- Plasminogen Activator Inhibitor (PAI-1) and Non-insulin-dependent Diabetes in Pima Indians, South Asians and Europeans (1996) (19)
- Genetic admixture and gallbladder disease in Mexican Americans. (1998) (19)
- Parental longevity and diabetes risk in the Diabetes Prevention Program. (2011) (19)
- A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians. (2015) (18)
- Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes (2013) (18)
- HLA-A2 and Type 2 (insulin independent) diabetes mellitus in Pima Indians: An association of allele frequency with age (1981) (18)
- Urine metabolites are associated with glomerular lesions in type 2 diabetes (2018) (18)
- Cardiovascular autonomic neuropathy associates with nephropathy lesions in American Indians with type 2 diabetes. (2016) (18)
- Screening for mtDNA diabetes mutations in Pima Indians with NIDDM. (1995) (17)
- Obesity in Pima Indians: genetic segregation analyses of body mass index complicated by temporal increases in obesity. (1994) (17)
- Prevention of non-insulin-dependent diabetes mellitus. (1994) (17)
- Incidence of diabetes mellitus in women following impaired glucose tolerance in pregnancy is lower than following impaired glucose tolerance in the non-pregnant state (1996) (16)
- Molecular variation at the HLA-A, B, C, DRB1, DQA1, and DQB1 loci in full heritage American Indians in Arizona: private haplotypes and their evolution. (2009) (16)
- Diabetes autoantibodies do not predict progression to diabetes in adults: the Diabetes Prevention Program (2014) (16)
- Measurement characteristics of the ankle–brachial index: results from the Action for Health in Diabetes study (2008) (16)
- One-Hour Plasma Glucose Compared With Two-Hour Plasma Glucose in Relation to Diabetic Retinopathy in American Indians (2018) (16)
- Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex‐specific diabetes signals in GLIS3 and ZFAND3 (2017) (16)
- Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. (2015) (16)
- Weight fluctuation, mortality and vascular disease in Pima Indians. (1996) (16)
- Early and late insulin response as predictors of NIDDM in Pima Indians with impaired glucose tolerance (1995) (16)
- Plasma lipoproteins and the incidence of abnormal excretion of albumin in diabetic American Indians: The Strong Heart Study (1998) (16)
- Preventing diabetes in obese Latino youth with prediabetes: a study protocol for a randomized controlled trial (2017) (16)
- Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation (2017) (16)
- Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study (2020) (15)
- Weight Loss Experiences of African American, Hispanic, and Non‐Hispanic White Men and Women with Type 2 Diabetes: The Look AHEAD Trial (2019) (15)
- Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention (2017) (15)
- Parental hypertension and proteinuria in Pima Indians with NIDDM (1996) (15)
- Electrocardiographic abnormalities predict deaths from cardiovascular disease and ischemic heart disease in Pima Indians with type 2 diabetes. (2006) (15)
- Hypertension in Pima Indians: prevalence and predictors. (1996) (15)
- Survival During Renal Replacement Therapy for Diabetic End-Stage Renal Disease in Pima Indians (1996) (15)
- Long-Term Effects of Lifestyle Intervention and Metformin during DPP on Appendicular Lean Mass (2018) (15)
- Effect of Intrauterine Diabetes Exposure on the Incidence of End-Stage Renal Disease in Young Adults With Type 2 Diabetes (2010) (15)
- Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis (2021) (15)
- HLA and B-lymphocyte alloantigens in Gila River Indians. (2008) (14)
- Genetic Ancestry Markers and Difference in A1c Between African American and White in the Diabetes Prevention Program (2018) (14)
- Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes. (2020) (14)
- Growth Tracking in Severely Obese or Underweight Children (2017) (14)
- Autoantibodies against PFDN2 are associated with an increased risk of type 2 diabetes: A case‐control study (2017) (14)
- Infertility, gravidity, and risk of diabetes among high-risk women in the Diabetes Prevention Program Outcomes Study. (2020) (13)
- Trends in heart disease death rates in diabetic and nondiabetic Pima Indians. (2006) (13)
- Use of graded Semmes Weinstein monofilament testing for ascertaining peripheral neuropathy in people with and without diabetes. (2019) (13)
- Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians (2016) (13)
- Obesity in Pima Indians. Distribution characteristics and possible thresholds for genetic studies. (1992) (13)
- Between-Monitor Differences in Step Counts Are Related to Body Size: Implications for Objective Physical Activity Measurement (2011) (13)
- H. pylori seroprevalence and risk of diabetes: An ancillary case-control study nested in the diabetes prevention program. (2017) (13)
- Natural history of diabetic nephropathy in non-insulin-dependent diabetes mellitus. (1991) (12)
- Genome‐wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations—significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group (2009) (12)
- Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study (2021) (12)
- Response to Comment on: Chakkera et al. Can New-Onset Diabetes After Kidney Transplant Be Prevented? Diabetes Care 2013;36:1406–1412 (2013) (12)
- Development of Impaired Glucose Tolerance With or Without Weight Gain (1993) (12)
- Weight maintenance from young adult weight predicts better health outcomes (2014) (12)
- Familial Aggregation of Medial Arterial Calcification in Pima Indians With and Without Diabetes (1996) (12)
- Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion (2015) (12)
- Vitamin D supplementation for prevention of cancer: the D2d cancer outcomes (D2dCA) ancillary study. (2021) (12)
- Association of Serum Amyloid A with Kidney Outcomes and All-Cause Mortality in American Indians with Type 2 Diabetes (2017) (11)
- Secular Trends in Treatment and Control of Type 2 Diabetes in an American Indian Population: A 30-Year Longitudinal Study (2010) (11)
- Islet autoantibody positivity in overweight and obese adults with type 2 diabetes (2018) (11)
- Impact of an 8‐Year Intensive Lifestyle Intervention on an Index of Multimorbidity (2020) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Preventing Diabetes in American Indian Communities (2013) (11)
- Long-term Effect of Losartan on Kidney Disease in American Indians With Type 2 Diabetes: A Follow-up Analysis of a Randomized Clinical Trial (2016) (11)
- Depressive Symptoms, Antidepressant Medication Use, and Inflammatory Markers in the Diabetes Prevention Program (2017) (10)
- Maternal Influence, Not Diabetic Intrauterine Environment, Predicts Children's Energy Intake (2009) (10)
- Depressive Symptoms, Antidepressant Medication Use, and New Onset of Diabetes in Participants of the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study (2015) (10)
- Replication of the Association of BDNF and MC4R Variants With Dietary Intake in the Diabetes Prevention Program (2016) (10)
- Cardiometabolic risk profile based on body mass index in American Indian children and adolescents (2017) (10)
- Association of albuminuria with all-cause and cardiovascular disease mortality in diabetes: the Strong Heart Study: (2005) (10)
- Assessing the Role of 98 Established Loci for Body Mass Index in American Indians (2019) (10)
- Genealogy construction in a historically isolated population: Application to genetic studies of rheumatoid arthritis in the Pima Indian (1999) (10)
- Four-Year Change in Cardiorespiratory FitnessandIn fl uenceonGlycemicControl in AdultsWith Type 2 Diabetes in a Randomized Trial The Look AHEAD Trial (2012) (10)
- Characterization of exome variants and their metabolic impact in 6,716 American Indians from Southwest US (2020) (10)
- Obesity indices derived from weight and height. (1982) (9)
- The effect of differing patterns of childhood body mass index gain on adult physiology in American Indians (2015) (9)
- HLA*A2 confers mortality risk for cardiovascular disease in Pimans. (1996) (9)
- Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP (2014) (9)
- Effect of different methods of accounting for antihypertensive treatment when assessing the relationship between diabetes or obesity and systolic blood pressure. (2017) (9)
- Genetic factors and susceptibility to diabetic nephropathy. (1988) (9)
- Quantitative trait linkage studies of diabetes-related traits (2003) (9)
- Birthweight and early-onset type 2 diabetes in American Indians: differential effects in adolescents and young adults and additive effects of genotype, BMI and maternal diabetes (2019) (8)
- Paleoindian Mitochondrial DNAs Have Rate Asian Mutations at High Frequencies Suggesting a Limited Number of Founders (1989) (8)
- Report of the North American Indian anthropology section (1992) (8)
- Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors (2019) (8)
- Changing course of diabetic nephropathy in the Pima Indians. (2008) (8)
- Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA (2018) (8)
- Assessing FOXO1A as a Potential Susceptibility Locus for Type 2 Diabetes and Obesity in American Indians (2015) (8)
- Incidence of Arg506 → GIn Mutation (Factor V Leiden) in Pima Indians (1997) (8)
- A Polygenic Lipodystrophy Genetic Risk Score Characterizes Risk Independent of BMI in the Diabetes Prevention Program (2019) (8)
- Dietary calcium and blood pressure in a Native American population. (1998) (8)
- Perspectives in Diabetes Preventing Non-Insulin-Dependent Diabetes (1995) (8)
- Prevalence of Non-Insulin-Dependent Diabetes (2005) (7)
- Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial (2018) (7)
- Study design of the Maycoba Project: obesity and diabetes in Mexican Pimas. (2014) (7)
- Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians. (2019) (7)
- Waist Circumference Change During Intensive Lifestyle Intervention and Cardiovascular Morbidity and Mortality in the Look AHEAD Trial (2020) (7)
- Interaction of diabetes genetic risk and successful lifestyle modification in the Diabetes Prevention Programme (2020) (7)
- Prevention of type 2 diabetes: comment on "Lifestyle modification and prevention of type 2 diabetes in overweight Japanese with impaired fasting glucose levels". (2011) (7)
- Pharmacologic Randomized Clinical Trials in Prevention of Type 2 Diabetes (2019) (7)
- Serum lipids and mortality in an American Indian population: A longitudinal study. (2018) (7)
- Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
- Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD (2015) (6)
- Physiology of the Aging Vasculature The Gly 482 Ser genotype at the PPARGC 1 A gene and elevated blood pressure : a meta-analysis involving 13 , 949 individuals (2008) (6)
- The natural history of renal disease in non-insulin-dependent diabetes mellitus: lessons from the Pima Indians. (1995) (6)
- Weight tracking in childhood and adolescence and type 2 diabetes risk (2020) (6)
- 37-OR: Racial and Socioeconomic Disparities in the Use of Newer Classes of Diabetes Medications (2020) (6)
- Effect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes (2021) (6)
- High risk of sacroiliitis in HLA--B27-positive Pima Indian men. (1982) (6)
- Variants in ASK 1 are Associated with Skeletal Muscle ASK 1 Expression , in vivo Insulin Resistance , and Type 2 Diabetes in Pima Indians Running (2010) (6)
- TCF 7 L 2 Polymorphism , Weight Loss and Proinsulin : Insulin Ratio in the Diabetes Prevention Program (2011) (6)
- Impact of weight loss on ankle‐brachial index and interartery blood pressures (2014) (6)
- Within-Trial Cost-Effectiveness of a Structured Lifestyle Intervention in Adults With Overweight/Obesity and Type 2 Diabetes: Results From the Action for Health in Diabetes (Look AHEAD) Study. (2020) (6)
- Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program (2016) (6)
- Antecedent events for non-insulin dependent diabetes mellitus. (1988) (5)
- Prediabetic blood pressure and familial predisposition to renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. (1995) (5)
- Familial Factors in Diabetic Nephropathy (2000) (5)
- Pima Indian Contributions to Our Understanding of Diabetic Kidney Disease (2021) (5)
- The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience (2022) (5)
- The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience (2022) (5)
- Effect of diabetes in pregnancy on offspring: Follow-up research in the pima indians (2000) (5)
- History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial (2020) (5)
- Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials (2009) (5)
- Approaches to Studying the Genetics of Type 2 Diabetes (1993) (5)
- Epidemiology of cholelithiasis in the Pima Indians (1984) (5)
- A genome-wide admixture scan identifies MYH 9 as a candidate locus associated with non-diabetic end stage renal disease in African Americans (2009) (5)
- Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d)Study:ADiabetesPrevention Trial (2014) (5)
- Attenuated Early Pregnancy Weight Gain by Prenatal Lifestyle Interventions Does Not Prevent Gestational Diabetes in the LIFE-Moms Consortium. (2020) (5)
- The relationship between insulin sensitivity and maximal oxygen uptake is confounded by method of adjustment for body composition (2013) (5)
- Assessing Accuracy of Genotype Imputation in American Indians (2014) (5)
- Analytic strategies to detect linkage to a common disorder with genetically determined age of onset: Diabetes mellitus in Pima Indians (1998) (5)
- The separate and joint effects of prolonged QT interval and heart rate on mortality. (2010) (4)
- Reproducibility of a prediabetes classification in a contemporary population (2020) (4)
- Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) (2016) (4)
- Yields and costs of recruitment methods with participant phenotypic characteristics for a diabetes prevention research study in an underrepresented pediatric population (2020) (4)
- Seroprevalence study of hantavirus antibodies in Pima Indians with renal disease. (1995) (4)
- Self-Reported Gastrointestinal Symptoms in Type 2 Diabetes Improve With an Intensive Lifestyle Intervention: Results From the Action for Health in Diabetes (Look AHEAD) Clinical Trial (2015) (4)
- Association of Trp64Arg mutation of the beta 3-adrenergic receptor gene with NIDDM. (1996) (4)
- Non‐Caucasian North American Populations: Native Americans (2002) (4)
- Weight Change During the Postintervention Follow-up of Look AHEAD. (2022) (4)
- American Indian Demographic History and Cultural Affiliation : A Discussion of Certain Limitations on the Use of mtDNA and Y Chromosome Testing (2002) (4)
- Stability of Body Weight in Type 2 Diabetes (2006) (4)
- THE ASSOCIATION BETWEEN PHYSICAL ACTIVITY AND GALLBLADDER DISEASE AMONG PIMA INDIANS.: 325 (1995) (4)
- Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study—a randomized trial in persons with prediabetes (2022) (3)
- Changing Glucose Tolerance during Pregnancy—Implications for Diagnosis of Gestational Diabetes Mellitus (GDM) (2018) (3)
- Symptom prevalence differences of depression as measured by BDI and PHQ scales in the Look AHEAD study (2019) (3)
- Energy expenditure and body-weight gain. (1988) (3)
- Diabetes, Hypertension, and Kidney Disease in the Pima Indians (2000) (3)
- Exome Sequencing of 21 Bardet‐Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians (2021) (3)
- Identification and functional analysis of a novel G310D variant in the insulin‐like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians (2018) (3)
- Exome sequencing identifies a nonsense variant in DAO associated with reduced energy expenditure in American Indians. (2020) (3)
- Diabetes mellitus, obesity and cholelithiasis (1984) (3)
- Simple Anthropometrics Are More Correlated with Health Variables than Are Estimates of Body Composition in Yup’ik People (2012) (3)
- The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS) (2022) (3)
- Effects of a Diabetes Prevention Program on Type 2 Diabetes Risk Factors and Quality of Life Among Latino Youths With Prediabetes (2022) (3)
- Risk Factors for the Development of Retinopathy in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Experience. (2022) (2)
- Erratum. Association of Weight Loss Maintenance and Weight Regain on 4-Year Changes in CVD Risk Factors: the Action for Health in Diabetes (Look AHEAD) Clinical Trial. Diabetes Care 2016;39:1345—1355 (2016) (2)
- Erratum. Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes. Diabetes 2013;62:3224–3231 (2018) (2)
- Urine metabolites are associated with glomerular lesions in type 2 diabetes (2018) (2)
- Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study (2020) (2)
- Diabetes, Hypertension, and Kidney Disease in the Pima Indians Compared with Other Populations (1994) (2)
- White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes. (2017) (2)
- Per- and polyfluoroalkyl substance plasma concentrations and metabolomic markers of type 2 diabetes in the Diabetes Prevention Program trial. (2020) (2)
- Erratum: Steroid sex hormones, sex hormone binding globulin, and diabetes incidence in the diabetes prevention program (The Journal of Clinical Endocrinology & Metabolism (2015) 100:10 (3778-3786) DOI: 10.1210/jc.2015-2328) (2015) (2)
- Recent epidemiological contributions to the pathogenesis and etiology of non-insulin dependent diabetes. (1987) (2)
- Impact of Weight Loss on Ankle-Brachial Index and Inter-Artery Blood Pressures in Overweight and Obese Adults with Diabetes (2013) (2)
- Diabetic kidneys do deserve a lifestyle change. (2014) (2)
- Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence (2020) (2)
- Changes in mood and health‐related quality of life in Look AHEAD 6 years after termination of the lifestyle intervention (2021) (2)
- Genetic Predictors of Change in Waist Circumference and Waist-To-Hip Ratio with Lifestyle Intervention: the Trans-NIH consortium for Genetics of Weight Loss Response to Lifestyle Intervention (2022) (2)
- Preventing Diabetes in American Indian Communities. Diabetes Care (2014) (2)
- Effect of a Long-Term Behavioral Weight Loss Intervention on Nephropathy in Overweight or Obese Adults with Type 2 Diabetes: the Look AHEAD Randomized Clinical Trial (2015) (2)
- Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668–1677 (2018) (1)
- Association of Metformin With the Development of Age-Related Macular Degeneration. (2022) (1)
- Enlarged acetabular labra in the Pima Indians. (1997) (1)
- Response to Comment on Knowler et al. Preventing Diabetes in American Indian Communities. Diabetes Care 2013;36:1820–1822 (2014) (1)
- RETRACTED ARTICLE: Common variation in PPARGC1A/B and progression to diabetes or change in metabolic traits following preventive interventions: the Diabetes Prevention Program (2013) (1)
- Treatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort (2015) (1)
- Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians (2022) (1)
- Genetic Score Based on 34 Con fi rmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program (2011) (1)
- 1709-P: Assessing the Role of 211 “Established” Type 2 Diabetes Variants in American Indians (2019) (1)
- Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index. (2021) (1)
- 28-OR: Identification of Ancestry-Specific Alleles in a Genome-Wide Association Study (GWAS) for Metformin (MET) Response in the Diabetes Prevention Program (DPP) (2021) (1)
- The Moderating Effects of Genetic Variations on Changes in Physical Activity Level and Cardiorespiratory Fitness in Response to a Life-Style Intervention: A Randomized Controlled Trial (2021) (1)
- 1715-P: Identifying Potentially Functional Variants in Regulatory Regions in KCNQ1 that Associate with Type 2 Diabetes in American Indians (2019) (1)
- Response to Comment on: Chakkera et al. Pretransplant Risk Score for New-Onset Diabetes After Kidney Transplantation. Diabetes Care 2011;34:2141–2145 (2012) (1)
- Abstract A23: Cancer outcomes in the diabetes prevention program outcomes study (2015) (1)
- Diabetes and Chronic Kidney Disease (2010) (1)
- Associations of Dietary Carbohydrates and Carbohydrate Subtypes with Diabetes Risk Factors in the Diabetes Prevention Program (2016) (1)
- Abstract 13378: Objectively Measured Total Physical Activity Rather Than Moderate-to-Vigorous Activity is Associated with Cardiovascular Risk Factors in Yup'ik Eskimo People (2011) (1)
- The Look AHEAD study: a missed opportunity--authors' reply. (2014) (1)
- Identification of Genetic Variation Influencing Metformin Response in a Multi-Ancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP). (2022) (1)
- Abstract MP13: Lipid Peroxidation And Inflammatory Response Differentiate With Changes In Liver Fat Among Obese Latino Youth Following Lifestyle Intervention (2021) (1)
- Cardiorespiratory Fitness, BMI, Mortality, and Cardiovascular Disease in Adults with Overweight/Obesity and Type 2 Diabetes (2022) (1)
- Increased Adiposity and Low Height-for-age in Early Childhood are Associated with Later Metabolic Risk in American Indian Children and Adolescents. (2022) (1)
- Albuminuria and GFR distributions in diabetes Change in the distribution of albuminuria according to estimated glomerular filtration rate in Pima Indians with type 2 diabetes (2009) (1)
- Adiposity, related biomarkers, and type 2 diabetes after gestational diabetes: The Diabetes Prevention Program (2021) (1)
- Abstract P100: Changes In Adiponectin But Not Tnfα Predict Changes In Insulin Sensitivity Following Health Behavior Intervention Among Latino Youth (2022) (0)
- Plasmaandlipoprotein cholesterol andtriglyceride concentrations inthePimaIndians: distributions differing fromthose ofCaucasians (1983) (0)
- Abstract 48: Long-term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Evidence of Left Ventricular Hypertrophy: The Action for Health in Diabetes (Look AHEAD) Trial (2016) (0)
- 1241-P: Prevalence of Prediabetes and Type 2 Diabetes among a High-Risk Adolescent and Young Adult Population (2020) (0)
- Abstract 4058: A longitudinal Study of Risk Factors for the Incident Abnormal Albuminuria in Diabetic American Indians: The Strong Heart Study (2006) (0)
- Advanced Glycation End-Products Predict Loss of Renal Function and Correlate with Lesions of Diabetic Kidney Disease in American Indians with Type 2 Diabetes Running title : AGEs and Kidney Disease in Type 2 Diabetes (2016) (0)
- 363-OR: Weight Loss, Lifestyle Intervention, and Metformin Effects on the Longitudinal Relationship between Insulin Secretion and Sensitivity in the Diabetes Prevention Program (DPP) (2022) (0)
- 307-OR: Interaction of Diabetes Genetic Risk and Successful Lifestyle Modification in the Diabetes Prevention Program (2019) (0)
- Epidemiology of Type 2 Diabetes in Indigenous Communities in the United States (2021) (0)
- Impact of Lifestyle Q : 1 and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation (2017) (0)
- GWAS results in the Diabetes Prevention Program EXTENSION OF TYPE 2 DIABETES GENOME-WIDE ASSOCIATION SCAN RESULTS IN THE DIABETES PREVENTION PROGRAM (2008) (0)
- Genome-Wide Scan for Estimated GFR in Multi-Ethnic Diabetic Populations: The Family Investigation of Nephropathy and Diabetes of Nephropathy (2007) (0)
- 1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians (2020) (0)
- The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population (2023) (0)
- The Utility of a Type 2 Diabetes (T2D) Polygenic Score in Addition to Clinical Variables for Prediction of T2D Incidence in Birth, Youth, and Adult Cohorts (2021) (0)
- 1701-P: Genome-Wide Association Study Identifies Novel Potential Associations with Birth Weight in a Southwestern American Indian Population (2019) (0)
- 1184-P: Adolescent Growth Spurt and Type 2 Diabetes Risk in an American Indian Population (2022) (0)
- 1327-P: Baseline Characteristics of Latino Youth with Prediabetes: The Preventing Diabetes in Latino Youth Cohort (2019) (0)
- 11. FAMILIAL FACTORS IN DIABETIC NEPHROPAmV (1998) (0)
- 1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population (2020) (0)
- 1119-P: Persistent and Heterogeneous Long-Term Effects of the Diabetes Prevention Program (DPP) Intensive Lifestyle (ILS) Intervention on Diabetes Incidence (2022) (0)
- Lifestyle Intervention Fails to Reduce Rate of CV Events in T2DM but Has Favorable Effect on other Measures (2013) (0)
- Do Genetic Variations Predict Physical Activity Response To Lifestyle Intervention Among Obese Adults With Diabetes? (2020) (0)
- Letter: HL-A W27, and juvenile rheumatoid arthritis. (1975) (0)
- Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) (2016) (0)
- 987-P: Cost-Effectiveness of a Diabetes Prevention Program among Latino Youth with Prediabetes (2022) (0)
- Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders (2018) (0)
- 2116-P: A Pipeline to Explore Rare Variation Which Can Contribute to Extreme Obesity in American Indians (2019) (0)
- Changes in Fitness following a Behavioral Weight Loss Program in Severely Obese Individuals: 3056 (2011) (0)
- deserve a lifestyle change (2014) (0)
- 141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits (2022) (0)
- Relationship Between Insulin Secretion and Insulin Sensitivity and Its Role in Development of Type 2 Diabetes: Beyond the Disposition Index (2021) (0)
- American Indian DNAs Have Rare Asian Mutations. Draft for Review For Publication in American Journal of Human Genetics (1987) (0)
- 249-OR: Type 2 Diabetes (T2D) Genetic Clusters for Association with Glycemic Responses to Intervention for Diabetes Prevention (2021) (0)
- Correction to: Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP) (2018) (0)
- Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes (2013) (0)
- Clinical Characteristics and Outcomes of Pediatric Patients with Confirmed or Suspected COVID-19 within a Large Public Hospital System (2020) (0)
- Indices of hepatic steatosis and fibrosis in prediabetes and association with diabetes development in the vitamin D and type 2 diabetes study. (2023) (0)
- 1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis (2020) (0)
- 1653-P: Association between Genetic Admixture Estimates for Five Ancestral Populations and Diabetes-Related Traits in Pacific Islanders (2020) (0)
- Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index. (2021) (0)
- 1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes (2021) (0)
- 252-OR: Cardiorespiratory Fitness Predicts Lower Mortality Rates in Type 2 Diabetes (2019) (0)
- P12 Factor VII gene polymorphisms in Pima Indians: relationship to factor VII antigen levels and features of the insulin resistance syndrome (1998) (0)
- Long-Term Complications in Youth-Onset Type 2 Diabetes. (2021) (0)
- Prevention of Non-insulin-dependent Diabetes Mellitus - an Emerging Challenge for India (1995) (0)
- Periodontal disease incidence in type 2 diabetes (1990) (0)
- Contents Vol. 75, 2013 (2013) (0)
- Critical Appraisal Lifestyle intervention or treatment with metformin Which delays onset of type 2 diabetes (2002) (0)
- Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668—1677 (2019) (0)
- 347-OR: Effects of a Diabetes Prevention Program among Latino Youth with Prediabetes (2022) (0)
- Polymorphism inthe5'Flanking Region oftheHumanInsulin Gene (1984) (0)
- Theangiotensin-I converting enzyme (ACE) gene I/Dpolymorphism andACE levels in PimaIndians (1996) (0)
- 1253-P: Yields and Costs of Recruitment Methods with Participant Baseline Characteristics for a Diabetes Prevention Research Study in an Underserved Pediatric Population (2020) (0)
- Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index (2021) (0)
- Tests for diagnosing diabetes mellitus: Authors' reply (1994) (0)
- Erratum. Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Diabetes Care 2021;44:1062–1069 (2021) (0)
- Insulin resistance associated with lower rates of weight gain in Pima (2017) (0)
- Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults (2020) (0)
- Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels (2018) (0)
- OBESITY (1941) (0)
- Effect of Diabetes on Peripheral Neuropathy in an Adult U.S. Population (2018) (0)
- Cost-Effectiveness of Structured Lifestyle Intervention in Overweight and Obese Adults with Type 2 Diabetes—Results from the Action for Health in Diabetes (Look AHEAD) Study (2018) (0)
- The rising prevalence of obesity and high prevalence of diabetes among Pima Indians suggest that the incidence of diabetes (2007) (0)
- Genome-Wide Search for Linkage of Estimated Glomerular Filtration Rate (eGFR) in the Family and Diabetes (2013) (0)
- Relationship between Obesity, Cognitive Function, and Quality of Life Among Inner-City Minority Youth (2021) (0)
- 1507-P: Baseline Metabolite Profiles of Incident Type 2 Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program (DPP) (2019) (0)
- Weight loss, lifestyle intervention, and metformin affect longitudinal relationship of insulin secretion and sensitivity. (2022) (0)
- Adolescent Growth Spurt and Type 2 Diabetes Risk in Southwestern American Indians. (2023) (0)
- Genetic linkage of alcoholism and antisocial alcoholism: (552692012-024) (1998) (0)
- Comparison of ETDRS 7-Field to 4-Widefield Digital Imaging in the Evaluation of Diabetic Retinopathy Severity (2022) (0)
- The angiotensin-converting enzyme (ACE) gene I/D polymorphism and the association with plasma ACE levels in Pima Indians and Caucasian vascular disease patients (1995) (0)
- Differential Effects of Birth Weight on Early-Onset Type 2 Diabetes in Adolescents and Young Adults (2018) (0)
- Genetic Predictors ofWeight Loss and Weight Regain After Intensive Lifestyle Modi fi cation , Metformin Treatment , or Standard Care in the Diabetes Prevention Program (2011) (0)
- Running Title : Candidate genes in the Diabetes Prevention Program (2010) (0)
- Front & Back Matter (2013) (0)
- Habitual physical activity in children : the role of genes and the environment 1 – 3 (2005) (0)
- Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children (2014) (0)
- Supplementary Material for: Association of Serum Amyloid A with Kidney Outcomes and All-Cause Mortality in American Indians with Type 2 Diabetes (2017) (0)
- Optimal diet for glycemia and lipids. (2006) (0)
- Per- and polyfluoroalkyl substance plasma concentrations and metabolomic markers in the Diabetes Prevention Program (2020) (0)
- 1499-P: Apolipoprotein C-III as a Novel Predictor for T2D Incidence in Amerindians (2019) (0)
- Diabetic end-stage renal disease. (1990) (0)
- 125-OR: Child Growth Tracking and Type 2 Diabetes Risk: A Life Course Analysis (2019) (0)
- 2007-P: Weight Change and Intentionality of Weight Loss Relate to Mortality Risk in the Postintervention (Years 8-16) Phase of Look AHEAD (2020) (0)
- Genetic Markers Explain Differences in HbA1c Levels between African-American (AA) and Non-Hispanic White (NHW) Participants of the Diabetes Prevention Program (DPP) (2018) (0)
- 1526-P: Time-Dependent Effect of Kidney Disease on All-Cause and CVD Mortality in Adults with Type 2 Diabetes: A Secondary Analysis of the Look AHEAD Clinical Trial (2020) (0)
- Thirty-year trends in mortality among Pima Indians with and without diabetes Is ischemic heart disease an emerging problem? (2001) (0)
- Cardio-Metabolic Risk Profile Based on Body Mass Index in American Indian Children (2015) (0)
- Correction to: Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study—a randomized trial in persons with prediabetes (2022) (0)
- Body weight, parental hypertension, insulin, and birthweight as predictors of blood pressure in young adults (1995) (0)
- of a Pretransplant Risk Score for New-Onset Diabetes Mellitus After Kidney Transplantation (2013) (0)
- Public Health Genomics of Type 1 Diabetes, Type 2 Diabetes, and Diabetic Complications (2010) (0)
- 160-OR: Increased Adiposity and Low Height-for-Age in Early Childhood Is Associated with Later Metabolic Risk in American Indian Children and Adolescents (2021) (0)
- 200-OR: Optimal Use of Measures of Insulin Secretion and Sensitivity in Predicting Diabetes: Beyond the Disposition Index (2021) (0)
- Provider Preference for Growth Charts in Tracking Children with Obesity. (2020) (0)
- Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP) (2022) (0)
- Classification, epidemiology, diagnosis, and risk factors of diabetes (2014) (0)
- [Non-insulin-dependent diabetes mellitus: what we have learnt from studies carried out among Pima Indians]. (1990) (0)
- Genetic linkage of alcoholism and antisocial alcoholism (1999) (0)
- Plasminogen activator inhibitor-1 activity and 4G/5G promoter polymorphism in Pima Indians with and without diabetes (1995) (0)
- Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences. (2021) (0)
- RELATIONSHIP OF LOCUS OF CONTROL TO PHYSICAL ACTIVITY AMONG INDIVIDUALS WITH AND WITHOUT DIABETES.: 226 (1995) (0)
- 1998-P: Waist Circumference Change in the First Year of the Look AHEAD Trial Is Associated with Risk for Cardiovascular Morbidity and Mortality (2020) (0)
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What Schools Are Affiliated With William C. Knowler?
William C. Knowler is affiliated with the following schools:
