William A. Catterall
American pharmacologist
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William A. Catterall's Degrees
- Bachelors Chemistry University of Washington
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(Suggest an Edit or Addition)According to Wikipedia, William Albert Catterall is an American pharmacologist and neurobiologist, who researches ion channels. He currently serves as a professor of pharmacology at the University of Washington School of Medicine in Seattle, Washington and is known for the discovery of the sodium and calcium voltage-gated ion channels. Catterall received his B.A. in chemistry from Brown University in 1968 and his Ph.D. in physiological chemistry from Johns Hopkins University School of Medicine in 1972. He did his postdoctoral training in neurobiology and molecular pharmacology as a Muscular Dystrophy Association Fellow with Marshall Nirenberg at the NIH from 1972 to 1974. After three years as a staff scientist at the NIH, Catterall joined the University of Washington in 1977 as an associate professor of pharmacology. He earned full professorship in 1981 and served as chair of the University of Washington's pharmacology department from 1984 to 2016.
William A. Catterall's Published Works
Published Works
- International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels (2003) (7161)
- Structure and regulation of voltage-gated Ca2+ channels. (2000) (2313)
- From Ionic Currents to Molecular Mechanisms The Structure and Function of Voltage-Gated Sodium Channels (2000) (1989)
- International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels (2005) (1469)
- Nomenclature of Voltage-Gated Sodium Channels (2000) (1391)
- Voltage-gated calcium channels. (2011) (1292)
- International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels (2005) (1284)
- THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL (2011) (1233)
- Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. (1980) (1170)
- The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands (2015) (1100)
- Structure and function of voltage-sensitive ion channels. (1988) (1089)
- Nomenclature of Voltage-Gated Calcium Channels (2000) (895)
- Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy (2006) (842)
- Molecular determinants of state-dependent block of Na+ channels by local anesthetics. (1994) (816)
- A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation. (1992) (797)
- Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits (1993) (764)
- Cellular and molecular biology of voltage-gated sodium channels. (1992) (727)
- Modulation of Ca2+ channels βγ G-protein py subunits (1996) (719)
- Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. (1992) (676)
- Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. (2000) (661)
- Overview of the voltage-gated sodium channel family (2003) (652)
- Calcium Channel Regulation and Presynaptic Plasticity (2008) (624)
- Structure and function of voltage-gated ion channels. (1995) (611)
- Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels (1995) (601)
- Auxiliary subunits of voltage-gated ion channels (1994) (557)
- Voltage-gated ion channels and gating modifier toxins. (2007) (551)
- Molecular properties of voltage-sensitive sodium channels. (1986) (537)
- Voltage‐gated sodium channels at 60: structure, function and pathophysiology (2012) (535)
- Structure and function of voltage-gated ion channels (1993) (534)
- Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons (1990) (502)
- Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit (1992) (500)
- Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif (1995) (474)
- Ca2+/calmodulin binds to and modulates P/Q-type calcium channels (1999) (468)
- Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. (1996) (462)
- Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily (2005) (453)
- Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle. (1987) (444)
- Calcium Channel Types with Distinct Presynaptic Localization Couple Differentially to Transmitter Release in Single Calyx-Type Synapses (1999) (439)
- Identification of a syntaxin-binding site on N-Type calcium channels (1994) (439)
- The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis (2004) (438)
- Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology (2010) (438)
- Autistic behavior in Scn1a+/− mice and rescue by enhanced GABAergic transmission (2012) (437)
- Crystal structure of a voltage-gated sodium channel in two potentially inactivated states (2012) (426)
- Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules. (1984) (420)
- Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons (1989) (420)
- Molecular Determinants of High Affinity Binding of α-Scorpion Toxin and Sea Anemone Toxin in the S3-S4 Extracellular Loop in Domain IV of the Na+ Channel α Subunit* (1996) (414)
- Structure and function of neuronal Ca2+ channels and their role in neurotransmitter release. (1998) (398)
- Identification of an intracellular peptide segment involved in sodium channel inactivation. (1988) (391)
- Localization of Ca2+ Channel Subtypes on Rat Spinal Motor Neurons, Interneurons, and Nerve Terminals (1998) (389)
- The naming of voltage-gated calcium channels (1994) (371)
- Calcium-dependent interaction of N-type calcium channels with the synaptic core complex (1996) (367)
- Molecular determinants of drug binding and action on L-type calcium channels. (1997) (363)
- Receptor sites for Ca2+ channel antagonists. (1992) (358)
- Sodium Channel β4, a New Disulfide-Linked Auxiliary Subunit with Similarity to β2 (2003) (352)
- Neuromodulation of Na+ channels: An unexpected form of cellular platicity (2001) (349)
- NaV1.1 channels and epilepsy (2010) (348)
- Functional modulation of brain sodium channels by protein kinase C phosphorylation. (1991) (330)
- Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25. (1996) (321)
- Modulation of Ca2+ channels by G-protein βγ subunits (1996) (320)
- A rat brain na+ channel α subunit with novel gating properties (1988) (314)
- Voltage Sensor–Trapping Enhanced Activation of Sodium Channels by β-Scorpion Toxin Bound to the S3–S4 Loop in Domain II (1998) (313)
- The molecular basis of neuronal excitability. (1984) (310)
- International Union of Pharmacology. XL. Compendium of Voltage-Gated Ion Channels: Calcium Channels (2003) (302)
- An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart (2002) (298)
- The sodium channel from rat brain. Purification and subunit composition. (1984) (297)
- Inhibition of Neurotransmission by Peptides Containing the Synaptic Protein Interaction Site of N-Type Ca2+ Channels (1996) (291)
- Common modes of drug action on Na+ channels: local anesthetics, antiarrhythmics and anticonvulsants (1987) (289)
- Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase. (1996) (288)
- Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel. (1992) (287)
- Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retina (1990) (286)
- Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy (2007) (282)
- Structural basis for Ca2+ selectivity of a voltage-gated calcium channel (2013) (279)
- Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease (2018) (278)
- Gating pore current in an inherited ion channelopathy (2007) (274)
- Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase (1993) (270)
- Interactions of Presynaptic Ca2+ Channels and Snare Proteins in Neurotransmitter Release (1999) (268)
- Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase. (1993) (268)
- Modulation of Ca2+ channels by G-protein beta gamma subunits. (1996) (260)
- A phosphorylation site in the Na+ channel required for modulation by protein kinase C. (1991) (258)
- Mice Lacking Sodium Channel β1 Subunits Display Defects in Neuronal Excitability, Sodium Channel Expression, and Nodal Architecture (2004) (258)
- Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker. (1992) (258)
- The Concise Guide to PHARMACOLOGY 2015/16: Overview (2015) (256)
- Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome (2012) (252)
- Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R. (1998) (252)
- Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP (2005) (251)
- The Concise Guide to Pharmacology 2013/14: Ion Channels (2013) (249)
- Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome (2017) (245)
- Distinct Subcellular Localization of Different Sodium Channel &agr; and &bgr; Subunits in Single Ventricular Myocytes From Mouse Heart (2004) (243)
- Functional modulation of brain sodium channels by cAMP-dependent phosphorylation (1992) (243)
- Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases (2008) (240)
- Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene. (1990) (239)
- Molecular Determinants of Voltage-dependent Gating and Binding of Pore-blocking Drugs in Transmembrane Segment IIIS6 of the Na+ Channel α Subunit* (2001) (239)
- Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. (1985) (233)
- β-Adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15 (2003) (230)
- Structural basis for gating charge movement in the voltage sensor of a sodium channel (2011) (227)
- Reduced Sodium Current in Purkinje Neurons from NaV1.1 Mutant Mice: Implications for Ataxia in Severe Myoclonic Epilepsy in Infancy (2007) (227)
- Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs. (1991) (226)
- Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels. (2006) (226)
- Sudden unexpected death in a mouse model of Dravet syndrome. (2013) (222)
- IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels (2008) (220)
- Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. (1992) (219)
- Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit. (1997) (216)
- Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase. (1985) (216)
- Inhibition of inactivation of single sodium channels by a site-directed antibody. (1989) (215)
- Molecular properties of dihydropyridine-sensitive calcium channels in skeletal muscle. (1988) (213)
- Role of Amino Acid Residues in Transmembrane Segments IS6 and IIS6 of the Na+ Channel α Subunit in Voltage-dependent Gating and Drug Block* (2002) (211)
- Functional Co-expression of the 1 and Type IIA Subunits of Sodium Channels in a Mammalian Cell Line (*) (1995) (210)
- N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons. (1996) (208)
- Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit. (1992) (204)
- An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node (2003) (201)
- Biosynthesis and processing of the α subunit of the voltage-sensitive sodium channel in rat brain neurons (1986) (199)
- Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy (2009) (199)
- Enhancement of Inhibitory Neurotransmission by GABAA Receptors Having α2,3-Subunits Ameliorates Behavioral Deficits in a Mouse Model of Autism (2014) (195)
- Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel β2-subunits (2002) (195)
- Excitation-contraction coupling in vertebrate skeletal muscle: A tale of two calcium channels (1991) (194)
- The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels (2015) (193)
- A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation* (1998) (190)
- Primary Structure and Function of an A Kinase Anchoring Protein Associated with Calcium Channels (1998) (189)
- A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase β (2000) (187)
- The adult rat brain β1 subunit modifies activation and inactivation gating of multiple sodium channel α subunits (1994) (186)
- Alteration of Ca2+ Dependence of Neurotransmitter Release by Disruption of Ca2+ Channel/Syntaxin Interaction (1997) (185)
- Purification of the saxitoxin receptor of the sodium channel from rat brain. (1981) (185)
- Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. (2003) (184)
- Molecular Mechanism of Calcium Channel Regulation in the Fight-or-Flight Response (2010) (184)
- Increased Expression of the Cardiac L-type Calcium Channel in Estrogen Receptor–deficient Mice (1997) (183)
- Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase. (1993) (183)
- International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands (2014) (183)
- Membrane potential-dependent binding of scorpion toxin to the action potential Na+ ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination. (1977) (183)
- The Extracellular Matrix Molecule Hyaluronic Acid Regulates Hippocampal Synaptic Plasticity by Modulating Postsynaptic L-Type Ca2+ Channels (2010) (183)
- Ca2+/Calmodulin-Dependent Facilitation and Inactivation of P/Q-Type Ca2+ Channels (2000) (183)
- Structure and function of voltage‐gated sodium channels at atomic resolution (2014) (181)
- Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. (1982) (181)
- A Critical Role for Transmembrane Segment IVS6 of the Sodium Channel α Subunit in Fast Inactivation (*) (1995) (180)
- Activation of the action potential Na+ ionophore of cultured neuroblastoma cells by veratridine and batrachotoxin. (1975) (179)
- Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase. (1994) (179)
- Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C‐terminal domain (2006) (178)
- The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy. (2007) (178)
- Sodium channel β1 and β3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain (2001) (178)
- Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins (1998) (178)
- Differential modulation of Cav2.1 channels by calmodulin and Ca2+-binding protein 1 (2002) (177)
- A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel. (1990) (176)
- Interaction of the synprint site of N-type Ca2+ channels with the C2B domain of synaptotagmin I. (1997) (176)
- Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by local anesthetics. (1984) (175)
- Ca 2 + / calmodulin binds to andmodulates P / Q-typecalciumchannels (174)
- Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome (2014) (174)
- Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes. (1979) (173)
- Muscarinic Modulation of Sodium Current by Activation of Protein Kinase C in Rat Hippocampal Neurons (1996) (173)
- Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit. (1993) (172)
- Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin (1999) (171)
- Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels (2010) (171)
- Subunits of purified calcium channels: a 212-kDa form of alpha 1 and partial amino acid sequence of a phosphorylation site of an independent beta subunit. (1989) (170)
- An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations (2012) (167)
- Functional subunit structure of voltage-gated calcium channels. (1991) (167)
- Biochemical properties and subcellular distribution of the neuronal class E calcium channel alpha 1 subunit (1995) (165)
- Restoration of inactivation and block of open sodium channels by an inactivation gate peptide (1994) (164)
- Dopaminergic Modulation of Sodium Current in Hippocampal Neurons via cAMP-Dependent Phosphorylation of Specific Sites in the Sodium Channel α Subunit (1997) (164)
- Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels. (1990) (161)
- Progress in Understanding and Treating SCN2A-Mediated Disorders (2018) (161)
- Molecular properties of brain sodium channels: an important target for anticonvulsant drugs. (1999) (161)
- The sodium channel from rat brain. Separation and characterization of subunits. (1985) (160)
- Upregulation of L-Type Ca2+ Channels in Reactive Astrocytes after Brain Injury, Hypomyelination, and Ischemia (1998) (159)
- Voltage-dependent gating of sodium channels: correlating structure and function (1986) (159)
- Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle. (1994) (159)
- Transmitter Modulation of Slow, Activity-Dependent Alterations in Sodium Channel Availability Endows Neurons with a Novel Form of Cellular Plasticity (2003) (158)
- Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin. (1980) (157)
- Molecular Determinants of Na+ Channel Function in the Extracellular Domain of the β1 Subunit* (1998) (156)
- Sodium uptake associated with activation of action potential ionophores of cultured neuroblastoma and muscle cells. (1973) (156)
- Binding of batrachotoxinin A 20-alpha-benzoate to a receptor site associated with sodium channels in synaptic nerve ending particles. (1981) (155)
- Regulation of Presynaptic CaV2.1 Channels by Ca2+ Sensor Proteins Mediates Short-Term Synaptic Plasticity (2008) (155)
- Palmitylation, sulfation, and glycosylation of the alpha subunit of the sodium channel. Role of post-translational modifications in channel assembly. (1987) (155)
- Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during β1-adrenergic regulation (2006) (154)
- Phosphorylation of the Synaptic Protein Interaction Site on N-type Calcium Channels Inhibits Interactions with SNARE Proteins (1997) (154)
- Tissue-specific expression of the RI and RII sodium channel subtypes. (1987) (153)
- Muscarinic acetylcholine receptors in developing chick heart. (1977) (153)
- Molecular determinants of Ca2+/calmodulin-dependent regulation of Cav2.1 channels (2003) (152)
- Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology. (1989) (151)
- Localization of sodium channels in axon hillocks and initial segments of retinal ganglion cells. (1986) (151)
- Sodium channels, inherited epilepsy, and antiepileptic drugs. (2014) (151)
- Adenosine triphosphatase from rat liver mitochondria. I. Purification, homogeneity, and physical properties. (1971) (151)
- Cyclic AMP-dependent phosphorylation of the alpha subunit of the sodium channel in synaptic nerve ending particles. (1984) (151)
- Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain. (2000) (149)
- Functional reconstitution of the purified brain sodium channel in planar lipid bilayers. (1985) (146)
- Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels (2015) (146)
- Structure of the Cardiac Sodium Channel (2019) (146)
- Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore. (1978) (145)
- Characterization of the two size forms of the alpha 1 subunit of skeletal muscle L-type calcium channels. (1991) (145)
- Physical Link and Functional Coupling of Presynaptic Calcium Channels and the Synaptic Vesicle Docking/Fusion Machinery (1998) (144)
- A Gating Hinge in Na+ Channels A Molecular Switch for Electrical Signaling (2004) (144)
- Identification of peptide components of the brevetoxin receptor site of rat brain sodium channels. (1994) (143)
- Molecular mechanisms of gating and drug block of sodium channels. (2002) (143)
- The Concise Guide to Pharmacology 2013/14: Overview (2013) (143)
- Neuromodulation of Na+ Channel Slow Inactivation via cAMP-Dependent Protein Kinase and Protein Kinase C (2006) (143)
- International Union of Pharmacology. XXXIX. Compendium of Voltage-Gated Ion Channels: Sodium Channels (2003) (143)
- The Concise Guide to Pharmacology 2013/14: Overview (2013) (143)
- Binding of scorpion toxin to receptor sites associated with sodium channels in frog muscle. Correlation of voltage-dependent binding with activation (1979) (142)
- Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase. (1997) (142)
- Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit. (1991) (141)
- Solution structure of the sodium channel inactivation gate. (1999) (141)
- Identification of a 15-kDa cAMP-dependent Protein Kinase-anchoring Protein Associated with Skeletal Muscle L-type Calcium Channels* (1997) (140)
- Glycosylation is required for maintenance of functional sodium channels in neuroblastoma cells. (1983) (140)
- Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP‐dependent protein kinase in hippocampal neurons. (1995) (139)
- Selective phosphorylation of the alpha subunit of the sodium channel by cAMP-dependent protein kinase. (1982) (138)
- A Novel Leucine Zipper Targets AKAP15 and Cyclic AMP-dependent Protein Kinase to the C Terminus of the Skeletal Muscle Ca2+ Channel and Modulates Its Function* (2002) (138)
- Modulation of Cardiac Na+ Channel Expression in Xenopus Oocytes by β1 Subunits (*) (1995) (137)
- Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs (2016) (136)
- Sequential formation of ion pairs during activation of a sodium channel voltage sensor (2009) (136)
- Reconstitution of the voltage-sensitive calcium channel purified from skeletal muscle transverse tubules. (1986) (135)
- Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain (1992) (135)
- Identification of 1,4-dihydropyridine binding regions within the alpha 1 subunit of skeletal muscle Ca2+ channels by photoaffinity labeling with diazipine. (1991) (134)
- Differential Modulation of Sodium Channel Gating and Persistent Sodium Currents by the β1, β2, and β3 Subunits (2001) (133)
- The sodium channel from rat brain (1986) (133)
- Molecular Determinants of High Affinity Phenylalkylamine Block of L-type Calcium Channels (*) (1995) (132)
- Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine. (1984) (132)
- The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunits. (1982) (131)
- Identification of the sites of selective phosphorylation and dephosphorylation of the rat brain Na+ channel alpha subunit by cAMP-dependent protein kinase and phosphoprotein phosphatases. (1993) (131)
- Ion Permeation through a Voltage- Sensitive Gating Pore in Brain Sodium Channels Having Voltage Sensor Mutations (2005) (131)
- The chemical basis for electrical signaling. (2017) (130)
- Electrical activity, cAMP, and cytosolic calcium regulate mRNA encoding sodium channel α subunits in rat muscle cells (1989) (129)
- Role of the C-terminal domain in inactivation of brain and cardiac sodium channels (2001) (128)
- Signaling complexes of voltage-gated sodium and calcium channels (2010) (127)
- A mutation in segment IVS6 disrupts fast inactivation of sodium channels. (1994) (126)
- Overview of the Alliance for Cellular Signaling (2002) (125)
- Calcium Channels and Short-term Synaptic Plasticity* (2013) (124)
- Na+ channel subunits and Ig domains (1996) (123)
- Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel. (1995) (122)
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels (2021) (122)
- Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin* (2006) (122)
- G-Protein β-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca2+ Channels (1998) (121)
- Membrane potential dependent binding of scorpion toxin to action potential Na+ ionophore. (1976) (121)
- Cooperative activation of action potential Na+ ionophore by neurotoxins. (1975) (121)
- Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice. (2011) (120)
- Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels (2003) (119)
- Localization of sodium channels in cultured neural cells (1981) (118)
- Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation (2008) (118)
- A large intracellular pool of inactive Na channel alpha subunits in developing rat brain. (1985) (118)
- Ca2+-dependent and -independent interactions of the isoforms of the alpha1A subunit of brain Ca2+ channels with presynaptic SNARE proteins. (1997) (118)
- AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling. (2014) (118)
- Molecular Determinants of High Affinity Dihydropyridine Binding in L-type Calcium Channels (*) (1996) (117)
- Selectivity of cations and nonelectrolytes for acetylcholine-activated channels in cultured muscle cells (1978) (117)
- Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C. (1994) (117)
- Role of calcium channel subtypes in calcium transients in hippocampal CA3 neurons (1995) (116)
- Persistent Sodium Currents through Brain Sodium Channels Induced by G Protein βγ Subunits (1997) (115)
- Purification of a toxic protein from scorpion venom which activates the action potential Na+ ionophore. (1976) (114)
- Activation of purified calcium channels by stoichiometric protein phosphorylation. (1989) (113)
- Molecular Determinants of High Affinity Phenylalkylamine Block of l-type Calcium Channels in Transmembrane Segment IIIS6 and the Pore Region of the α1Subunit* (1997) (112)
- Ion flux studies of voltage-sensitive sodium channels in synaptic nerve-ending particles. (1981) (111)
- Movement of the Na+ Channel Inactivation Gate during Inactivation* (1996) (110)
- Ins and outs (1994) (110)
- Mapping the receptor site for α-scorpion toxins on a Na+ channel voltage sensor (2011) (109)
- Catalysis of Na+ permeation in the bacterial sodium channel NaVAb (2013) (109)
- Interaction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel. (1998) (108)
- cAMP-dependent Phosphorylation of Two Sites in the α Subunit of the Cardiac Sodium Channel* (1996) (107)
- Biochemical properties of sodium channels in a wide range of excitable tissues studied with site-directed antibodies. (1988) (107)
- Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels. (2020) (107)
- Functional properties and differential neuromodulation of Nav1.6 channels (2008) (106)
- Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy (2017) (105)
- Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit. (1988) (105)
- Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1.1 channels in skeletal muscle. (2005) (104)
- Primary Structure and Functional Expression of the β 1 Subunit of the Rat Brain Sodium Channel (1992) (104)
- Voltage-Dependent Neuromodulation of Na+ Channels by D1-Like Dopamine Receptors in Rat Hippocampal Neurons (1999) (103)
- Mechanism of action of a polypeptide neurotoxin from the coral Goniopora on sodium channels in mouse neuroblastoma cells. (1986) (103)
- Efficient expression of rat brain type IIA Na+ channel α subunits in a somatic cell line (1992) (103)
- Solubilization of the calcium antagonist receptor from rat brain. (1983) (103)
- Structures of closed and open states of a voltage-gated sodium channel (2017) (103)
- The sodium channel from rat brain. Reconstitution of neurotoxin-activated ion flux and scorpion toxin binding from purified components. (1984) (102)
- Molecular Mechanism of Convergent Regulation of Brain Na+ Channels by Protein Kinase C and Protein Kinase A Anchored to AKAP-15 (2002) (101)
- Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel (2019) (101)
- Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C (1996) (101)
- Depolarization-activated gating pore current conducted by mutant sodium channels in potassium-sensitive normokalemic periodic paralysis (2008) (100)
- Toxin T4(6) from Ptychodiscus brevis (formerly Gymnodinium breve) enhances activation of voltage-sensitive sodium channels by veratridine. (1981) (100)
- Axonal L-type Ca2+ channels and anoxic injury in rat CNS white matter. (2001) (100)
- Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain (2008) (100)
- Electrical activity and cytosolic calcium regulate levels of tetrodotoxin-sensitive sodium channels in cultured rat muscle cells. (1984) (99)
- Localization of receptor sites for insect-selective toxins on sodium channels by site-directed antibodies. (1992) (98)
- Analysis of the Dihydropyridine Receptor Site ofl-type Calcium Channels by Alanine-scanning Mutagenesis* (1997) (97)
- Functional properties of rat brain sodium channels expressed in a somatic cell line. (1990) (97)
- Cyclic-AMP-dependent phosphorylation of voltage-sensitive sodium channels in primary cultures of rat brain neurons. (1987) (97)
- Dissecting the phenotypes of Dravet syndrome by gene deletion. (2015) (96)
- Modulation of CaV2.1 Channels by the Neuronal Calcium-Binding Protein Visinin-Like Protein-2 (2005) (95)
- Binding of scorpion toxin to receptor sites associated with voltage-sensitive sodium channels in synaptic nerve ending particles. (1978) (95)
- Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels (2003) (94)
- Identification of an intracellular domain of the sodium channel having multiple cAMP-dependent phosphorylation sites. (1987) (92)
- Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1. (2002) (92)
- A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation (2009) (92)
- Modulation of the Cloned Skeletal Muscle L-Type Ca2+Channel by Anchored cAMP-Dependent Protein Kinase (1997) (91)
- Inhibition of sodium channels by D600. (1979) (89)
- Inhibition of Sodium Channel Gating by Trapping the Domain II Voltage Sensor with Protoxin II (2008) (89)
- Molecular properties of sodium and calcium channels (1996) (89)
- AKAP15 Anchors cAMP-dependent Protein Kinase to Brain Sodium Channels* (1998) (88)
- NaV1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms (2012) (86)
- Evidence for a voltage-dependent enhancement of neurotransmitter release mediated via the synaptic protein interaction site of N-type Ca2+ channels. (1998) (86)
- The Extracellular Domain of the β1 Subunit Is Both Necessary and Sufficient for β1-like Modulation of Sodium Channel Gating* (1999) (86)
- Activation of the action potential Na+ ionophore by neurotoxins. An allosteric model. (1977) (86)
- Deletion of the Distal C Terminus of CaV1.2 Channels Leads to Loss of β-Adrenergic Regulation and Heart Failure in Vivo* (2011) (85)
- Computational Design of Transmembrane Pores (2020) (84)
- Mechanism of SNARE protein binding and regulation of Cav2 channels by phosphorylation of the synaptic protein interaction site (2005) (84)
- The Hodgkin-Huxley Heritage: From Channels to Circuits (2012) (83)
- Voltage clamp analysis of tetrodotoxin-sensitive and -insensitive sodium channels in rat muscle cells developing in vitro (1985) (83)
- Differential Proteolysis of the Full‐Length Form of the L‐Type Calcium Channel α1 Subunit by Calpain (1994) (83)
- Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini. (1994) (82)
- Molecular Analysis of the Putative Inactivation Particle in the Inactivation Gate of Brain Type IIA Na+ Channels (1997) (82)
- Modulation of brain Na+ channels by a G-protein-coupled pathway. (1994) (81)
- Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel. (1997) (80)
- Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons (2017) (80)
- Calcium Binding in the Pore of L-type Calcium Channels Modulates High Affinity Dihydropyridine Binding (*) (1995) (80)
- Class I and IV antiarrhythmic drugs and cytosolic calcium regulate mRNA encoding the sodium channel alpha subunit in rat cardiac muscle. (1992) (79)
- Phosphorylation of an alpha 1-like subunit of an omega-conotoxin-sensitive brain calcium channel by cAMP-dependent protein kinase and protein kinase. (1991) (79)
- Adenosine triphosphatase from rat liver mitochondria. 3. Subunit composition. (1973) (78)
- Subtype-selective reconstitution of synaptic transmission in sympathetic ganglion neurons by expression of exogenous calcium channels (2003) (77)
- High Affinity Binding of Pyrethroids to the α Subunit of Brain Sodium Channels (1997) (77)
- Molecular Determinants for Modulation of Persistent Sodium Current by G-Protein βγ Subunits (2005) (76)
- Interaction of brevetoxin A with a new receptor site on the sodium channel. (1985) (76)
- Biochemical properties and subcellular distribution of the BI and rbA isoforms of alpha 1A subunits of brain calcium channels (1996) (75)
- Dravet Syndrome: A Sodium Channel Interneuronopathy. (2018) (75)
- Cyclic adenosine 3':5'-monophosphate and cytosolic calcium exert opposing effects on biosynthesis of tetrodotoxin-sensitive sodium channels in rat muscle cells (1985) (75)
- The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits. (1994) (75)
- Beta 1 subunits of sodium channels. Studies with subunit-specific antibodies. (1990) (75)
- Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Cavβ subunits (2001) (74)
- Phosphoinositide 3-Kinase &ggr; Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases (2012) (74)
- Neutralization of Gating Charges in Domain II of the Sodium Channel α Subunit Enhances Voltage-Sensor Trapping by a β-Scorpion Toxin (2001) (74)
- Dopaminergic Modulation of Voltage-Gated Na+ Current in Rat Hippocampal Neurons Requires Anchoring of cAMP-Dependent Protein Kinase (1999) (72)
- Structure-Function Map of the Receptor Site for β-Scorpion Toxins in Domain II of Voltage-gated Sodium Channels* (2011) (71)
- Sodium transport by the acetylcholine receptor of cultured muscle cells. (1975) (71)
- Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor (2011) (71)
- Functional Roles of the Extracellular Segments of the Sodium Channel α Subunit in Voltage-dependent Gating and Modulation by β1 Subunits* (1999) (70)
- Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome (2015) (69)
- Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations (2010) (69)
- Differential Regulation of CaV2.1 Channels by Calcium-Binding Protein 1 and Visinin-Like Protein-2 Requires N-Terminal Myristoylation (2005) (68)
- Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome (2015) (68)
- The newborn rabbit sino‐atrial node expresses a neuronal type I‐like Na+ channel. (1997) (68)
- Molecular Analysis of Potential Hinge Residues in the Inactivation Gate of Brain Type IIA Na+ Channels (1997) (68)
- Developmental regulation of sodium channel expression in the rat forebrain. (1989) (68)
- Specific Modulation of Na+ Channels in Hippocampal Neurons by Protein Kinase Cϵ (2005) (67)
- Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry. (2013) (67)
- Cyclic AMP-dependent phosphorylation of two size forms of alpha 1 subunits of L-type calcium channels in rat skeletal muscle cells. (1990) (67)
- Identification of an alpha subunit of dihydropyridine-sensitive brain calcium channels. (1987) (67)
- Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response (2013) (66)
- Modulation of skeletal muscle sodium channels in a satellite cell line by protein kinase C (1994) (66)
- Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line. (1995) (66)
- Structure and function of voltage-gated sodium and calcium channels (1991) (65)
- Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits. (2001) (65)
- Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants (1979) (65)
- Insights into pathophysiology and therapy from a mouse model of Dravet syndrome (2011) (65)
- Molecular determinants of diltiazem block in domains IIIS6 and IVS6 of L-type Ca(2+) channels. (2000) (64)
- The IUPHAR compendium of voltage-gated ion channels (2002) (63)
- Retrograde labeling, enrichment, and characterization of retinal ganglion cells from the neonatal rat (1983) (63)
- Reconstitution of neurotoxin-stimulated sodium transport by the voltage-sensitive sodium channel purified from rat brain. (1982) (62)
- Phosphorylation of the alpha subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687. (1989) (62)
- The sodium channel from rat brain. Role of the beta 1 and beta 2 subunits in saxitoxin binding. (1986) (62)
- Photoaffinity labeling of the brevetoxin receptor on sodium channels in rat brain synaptosomes. (1991) (62)
- Cav1.3 channels produce persistent calcium sparklets, but Cav1.2 channels are responsible for sparklets in mouse arterial smooth muscle (2007) (62)
- Tetrodotoxin-sensitive sodium channels in rat muscle cells developing in vitro. (1983) (61)
- Distribution of high‐voltage‐activated calcium channels in cultured γ‐aminobutyric acidergic neurons from mouse cerebral cortex (2002) (61)
- Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase. (1992) (60)
- A rat brain Na+ channel alpha subunit with novel gating properties. (1988) (60)
- Adenosine triphosphatase from rat liver mitochondria. II. Interaction with adenosine diphosphate. (1972) (59)
- Deciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestors. (2015) (58)
- Distribution and function of sodium channel subtypes in human atrial myocardium. (2013) (58)
- Reversed voltage-dependent gating of a bacterial sodium channel with proline substitutions in the S6 transmembrane segment. (2004) (58)
- Binding to saxitoxin to electrically excitable neuroblastoma cells. (1978) (58)
- Modulation of sodium and calcium channels by protein phosphorylation and G proteins. (1997) (57)
- Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation (2012) (57)
- Functional Role of a C-Terminal Gβγ-Binding Domain of Cav2.2 Channels (2004) (57)
- Na+ channel function, regulation, structure, trafficking and sequestration (2015) (57)
- Sodium channel expression and assembly during development of retinal ganglion cells (1988) (57)
- Specific inhibition of [3H] saxitoxin binding to skeletal muscle sodium channels by geographutoxin II, a polypeptide channel blocker. (1986) (57)
- Sites of Selective cAMP-dependent Phosphorylation of the L-type Calcium Channel α1 Subunit from Intact Rabbit Skeletal Muscle Myotubes (*) (1995) (56)
- Mapping the Interaction Site for a β-Scorpion Toxin in the Pore Module of Domain III of Voltage-gated Na+ Channels* (2012) (56)
- β-Adrenergic–regulated phosphorylation of the skeletal muscle CaV1.1 channel in the fight-or-flight response (2010) (56)
- Structural biology: A 3D view of sodium channels (2001) (55)
- Sodium channels in planar lipid bilayers. Channel gating kinetics of purified sodium channels modified by batrachotoxin (1986) (55)
- Inhibition of voltage-sensitive sodium channels in neuroblastoma cells by antiarrhythmic drugs. (1981) (55)
- Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700 (2014) (54)
- Fenestrations control resting-state block of a voltage-gated sodium channel (2018) (54)
- Regulation of NaV1.2 Channels by Brain-Derived Neurotrophic Factor, TrkB, and Associated Fyn Kinase (2007) (54)
- cAMP-dependent phosphorylation of two sites in the alpha subunit of the cardiac sodium channel. (1996) (53)
- Molecular Requirements for Recognition of Brain Voltage-gated Sodium Channels by Scorpion α-Toxins* (2009) (53)
- Dihydropyridine-sensitive calcium channels in cardiac and skeletal muscle membranes: studies with antibodies against the alpha subunits. (1987) (53)
- Allosteric modulation of neurotoxin binding to voltage-sensitive sodium channels by Ptychodiscus brevis toxin 2. (1987) (52)
- Modulation of CaV1.2 Channels by Mg2+ Acting at an EF-hand Motif in the COOH-terminal Domain (2005) (52)
- Site of Covalent Labeling by a Photoreactive Batrachotoxin Derivative near Transmembrane Segment IS6 of the Sodium Channel Subunit (*) (1996) (51)
- Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin. (2006) (51)
- Neurotoxin binding and allosteric modulation at receptor sites 2 and 5 on purified and reconstituted rat brain sodium channels. (1993) (51)
- A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel (1993) (51)
- Molecular properties of a superfamily of plasma-membrane cation channels. (1994) (50)
- Fine-tuning synaptic plasticity by modulation of CaV2.1 channels with Ca2+ sensor proteins (2012) (48)
- Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome (2013) (48)
- Protective effect of the ketogenic diet in Scn1a mutant mice (2011) (48)
- Distinct effects of mutations in transmembrane segment IVS6 on block of L-type calcium channels by structurally similar phenylalkylamines. (1996) (48)
- Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL. (2000) (48)
- Phosphorylation of Cav1.2 on S1928 uncouples the L‐type Ca2+ channel from the β2 adrenergic receptor (2016) (47)
- Modulation of cardiac Na+ channel expression in Xenopus oocytes by beta 1 subunits. (1995) (47)
- Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes. (2013) (46)
- Structure and Modulation of Na+ and Ca2+ Channels (1993) (46)
- Functional Roles of a C-terminal Signaling Complex of CaV1 Channels and A-kinase Anchoring Protein 15 in Brain Neurons* (2011) (45)
- Immunochemical Identification and Differential Phosphorylation of Alternatively Spliced Forms of the α1A Subunit of Brain Calcium Channels (*) (1995) (45)
- Convergent regulation of skeletal muscle Ca2+ channels by dystrophin, the actin cytoskeleton, and cAMP-dependent protein kinase. (2005) (45)
- Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits. (1999) (44)
- Molecular determinants for modulation of persistent sodium current by G-protein betagamma subunits. (2005) (44)
- Histrionicotoxin enhances agonist-induced desensitization of acetylcholine receptor. (1977) (43)
- Tetrodotoxin-insensitive sodium channels. Binding of polypeptide neurotoxins in primary cultures of rat muscle cells. (1981) (43)
- Synergistic GABA-Enhancing Therapy against Seizures in a Mouse Model of Dravet Syndrome (2013) (43)
- The sodium channel from rat brain. Reconstitution of voltage-dependent scorpion toxin binding in vesicles of defined lipid composition. (1985) (43)
- Molecular Properties of Dihydropyridine‐Sensitive Calcium Channels (1988) (43)
- Pharmacological properties of sodium channels in cultured rat heart cells. (1981) (43)
- Biphasic regulation of development of the high-affinity saxitoxin receptor by innervation in rat skeletal muscle (1982) (42)
- Phosphorylation of purified rat brain Na+ channel reconstituted into phospholipid vesicles by protein kinase C. (1992) (42)
- Elucidation of the Molecular Basis of Selective Recognition Uncovers the Interaction Site for the Core Domain of Scorpion α-Toxins on Sodium Channels* (2011) (41)
- Regulation of Sodium and Calcium Channels by Signaling Complexes (2006) (41)
- Voltage clamp analysis of sodium channels in normal and scorpion toxin- resistant neuroblastoma cells (1984) (41)
- Phosphorylation of theα subunit of the sodium channel by protein kinase C (1984) (40)
- Differential labeling of the alpha and beta 1 subunits of the sodium channel by photoreactive derivatives of scorpion toxin. (1984) (40)
- Functional properties of rat brain sodium channels lacking the beta 1 or beta 2 subunit. (1986) (40)
- Correction for Fu et al., Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response (2014) (40)
- Sodium Channel Mutations and Epilepsy (2012) (40)
- Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to short-term synaptic plasticity in hippocampal neurons (2016) (39)
- Bidirectional Modulation of Transmitter Release by Calcium Channel/Syntaxin Interactions In Vivo (2007) (39)
- Identification of Benz(othi)azepine-binding Regions within L-type Calcium Channel α1 Subunits* (1996) (39)
- Structural Basis for Gating Pore Current in Periodic Paralysis (2018) (39)
- PDE4B mediates local feedback regulation of &bgr;1-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes (2014) (38)
- A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb (2013) (37)
- The emerging molecular view of the sodium channel (1982) (37)
- STRUCTURE AND REGULATION OF VOLTAGE-GATED Ca 2 + C HANNELS (2005) (36)
- The extracellular domain of the beta1 subunit is both necessary and sufficient for beta1-like modulation of sodium channel gating. (1999) (36)
- Sites and Molecular Mechanisms of Modulation of NaV1.2 Channels by Fyn Tyrosine Kinase (2007) (36)
- Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin (2020) (35)
- Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to long-term potentiation and spatial learning (2016) (34)
- Tetrodotoxin-insensitive sodium channels. Ion flux studies of neurotoxin action in a clonal rat muscle cell line. (1981) (34)
- Ca2+-independent Activation of Ca2+/Calmodulin-dependent Protein Kinase II Bound to the C-terminal Domain of CaV2.1 Calcium Channels* (2012) (34)
- Modulation of CaV2.1 channels by neuronal calcium sensor-1 induces short-term synaptic facilitation (2014) (34)
- The binding of an insect-selective neurotoxin and saxitoxin to insect neuronal membranes (1985) (33)
- Open-state structure and pore gating mechanism of the cardiac sodium channel (2021) (33)
- Hippocampal deletion of NaV1.1 channels in mice causes thermal seizures and cognitive deficit characteristic of Dravet Syndrome (2019) (33)
- Cooperative regulation of Cav1.2 channels by intracellular Mg2+, the proximal C-terminal EF-hand, and the distal C-terminal domain (2009) (33)
- Molecular properties of the sodium channel: a receptor for multiple neurotoxins. (1992) (32)
- Control of neuronal excitability by phosphorylation and dephosphorylation of sodium channels. (2006) (32)
- Differential Phosphorylation, Localization, and Function of Distinct α1 Subunits of Neuronal Calcium Channels (1994) (32)
- Allosteric Interactions Required for High-Affinity Binding of Dihydropyridine Antagonists to CaV1.1 Channels Are Modulated by Calcium in the Pore (2006) (32)
- Developmental changes in the sensitivity of embryonic heart cells to tetrodotoxin and D600. (1978) (32)
- Efficient expression of rat brain type IIA Na+ channel alpha subunits in a somatic cell line. (1992) (31)
- Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150 (2014) (31)
- Activation and inhibition of the action potential Na+ ionophore of cultured rat muscle cells by neurotoxins. (1976) (31)
- Molecular Properties of Calcium Channels in Skeletal Muscle and Neurons (1993) (30)
- The Conus toxin geographutoxin IL distinguishes two functional sodium channel subtypes in rat muscle cells developing in vitro (1987) (30)
- Dopamine modulation of neuronal Na+ channels requires binding of A kinase-anchoring protein 15and PKA by a modified leucine zipper motif (2007) (30)
- Reconstitution of the voltage-sensitive sodium channel of rat brain from solubilized components. (1981) (30)
- Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits. (1999) (30)
- Persistent sodium currents through brain sodium channels induced by G protein betagamma subunits. (1997) (29)
- Size characteristics of the solubilized saxitoxin receptor of the voltage-sensitive sodium channel from rat brain. (1980) (29)
- Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel (2001) (29)
- Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor (vol 108, pg 15426, 2011) (2014) (29)
- Nuclear magnetic resonance study of the conformation of nicotinamide--adenine dinucleotide and reduced nicotinamide--adenine dinucleotide in solution. (1969) (29)
- Identification of a 33-kilodalton cytoskeletal protein with high affinity for the sodium channel. (1988) (28)
- Association of rare missense variants in the second intracellular loop of NaV1.7 sodium channels with familial autism (2016) (28)
- Actions of a polypeptide toxin from the marine snail Conus striatus on voltage-sensitive sodium channels. (1987) (28)
- Beta 2 subunits of sodium channels from vertebrate brain. Studies with subunit-specific antibodies. (1987) (28)
- Regulation of cardiac ion channels by signaling complexes: role of modified leucine zipper motifs. (2004) (28)
- Kinetic Analysis of Block of Open Sodium Channels by a Peptide Containing the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the Inactivation Gate (1998) (28)
- Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel (2019) (27)
- Type II sodium channels in spinal cord astrocytes in situ: Immunocytochemical observations (1994) (27)
- Phosphorylation of the alpha subunit of the sodium channel by protein kinase C. (1984) (27)
- Loss of β-adrenergic–stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failure (2016) (27)
- Isoform‐specific expression of sodium channels in astrocytes in vitro: Immunocytochemical observations (1995) (26)
- Sodium Channelopathies of Skeletal Muscle and Brain. (2021) (26)
- G-Protein b-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca 2 1 Channels (1998) (26)
- Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac (2014) (25)
- KATP channel gain-of-function leads to increased myocardial L-type Ca2+ current and contractility in Cantu syndrome (2016) (25)
- Structural Basis for High-Affinity Trapping of the NaV1.7 Channel in Its Resting State by Tarantula Toxin. (2020) (25)
- Molecular properties of voltage-sensitive sodium and calcium channels. (1988) (24)
- Antigenic differences among the voltage-sensitive sodium channels in the peripheral and central nervous systems and skeletal muscle (1985) (24)
- Structure and chromosomal localization of the β2 subunit of the human brain sodium channel (1997) (23)
- Block of Brain Sodium Channels by Peptide Mimetics of the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the Inactivation Gate (1999) (22)
- MEMBRANE POTENTIAL DEPENDENT BINDING OF SCORPION TOXIN TO THE ACTION POTENTIAL SODIUM IONOPHORE. STUDIES WITH A 3‐(4‐HYDROXY 3‐[125I] IODOPHENYL) PROPIONYL DERIVATIVE (1978) (22)
- Asynchronous Ca2+ current conducted by voltage-gated Ca2+ (CaV)-2.1 and CaV2.2 channels and its implications for asynchronous neurotransmitter release (2012) (22)
- Interaction between batrachotoxin and yohimbine. (1978) (22)
- A One-Domain Voltage-Gated Sodium Channel in Bacteria (2001) (22)
- Purification and reconstitution of skeletal muscle calcium channels. (1992) (22)
- Decrease in density of INa is in the common final pathway to heart block in murine hearts overexpressing calcineurin. (2006) (21)
- Type II brain sodium channel expression in non-neuronal cells: embryonic rat osteoblasts. (1995) (21)
- SLC6 neurotransmitter transporter family (2013) (21)
- Control of Excitation/Inhibition Balance in a Hippocampal Circuit by Calcium Sensor Protein Regulation of Presynaptic Calcium Channels (2018) (21)
- High affinity binding of pyrethroids to the alpha subunit of brain sodium channels. (1997) (21)
- Increased expression of the beta3 subunit of voltage-gated Na+ channels in the spinal cord of the SOD1G93A mouse (2011) (20)
- Phosphorylation of a conserved protein kinase C site is required for modulation of Na+ currents in transfected Chinese hamster ovary cells. (1992) (20)
- Selective Dephosphorylation of the Subunits of Skeletal Muscle Calcium Channels by Purified Phosphoprotein Phosphatases (1993) (20)
- The conformational cycle of a prototypical voltage-gated sodium channel (2020) (20)
- Hydrophobic properties of the beta 1 and beta 2 subunits of the rat brain sodium channel. (1987) (20)
- Pharmacologic properties of voltage-sensitive sodium channels in chick muscle fibers developing in vitro. (1980) (20)
- Partial Agonist and Antagonist Activities of a Mutant Scorpion β-Toxin on Sodium Channels* (2010) (20)
- Selection of variant neuroblastoma clones with missing or altered sodium channels. (1979) (19)
- Tetrodotoxin-insensitive sodium channels in a cardiac cell line from a transgenic mouse. (1992) (18)
- Introduction to the IUPHAR Compendium of Voltage-Gated Ion Channels 2005 (2005) (18)
- New approaches to antiarrhythmic therapy: emerging therapeutic applications of the cell biology of cardiac arrhythmias(1). (2001) (18)
- Reconstitution of High‐Affinity Binding of a β‐Scorpion Toxin to Neurotoxin Receptor Site 4 on Purified Sodium Channels (1995) (18)
- Structure and Modulation of Voltage‐Gated Ion Channels (1991) (18)
- Site of covalent attachment of a-scorpion toxin derivatives in domain I of the sodium channel a subunit (18)
- Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. (2007) (17)
- Specific binding of the novel Na+ channel blocker PD85,639 to the alpha subunit of rat brain Na+ channels. (1993) (17)
- Interaction of polypeptide neurotoxins with a receptor site associated with voltage-sensitive sodium channels. (1980) (17)
- Functional role of a C-terminal Gbetagamma-binding domain of Ca(v)2.2 channels. (2004) (17)
- Molecular Determinants of CaV2.1 Channel Regulation by Calcium-binding Protein-1* (2011) (17)
- Studies of Voltage-Sensitive Sodium Channels in Cultured Cells Using Ion-Flux and Ligand-Binding Methods (1981) (17)
- Ca 2 1 / Calmodulin-Dependent Facilitation and Inactivation of P / Q-Type Ca 2 1 Channels (2000) (16)
- Phosphorylation of S 1505 in the Cardiac Na + Channel Inactivation Gate Is Required for Modulation by Protein Kinase C (2003) (16)
- Structure and Biosynthesis of Neuronal Sodium Channels (1986) (16)
- Erratum: Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy (Nature Neuroscience (2006) 9, (1142-1149)) (2007) (16)
- Cooperative regulation of Ca v 1.2 channels by intracellular Mg 2+ , the proximal C-terminal EF-hand, and the distal C-terminal domain (2009) (16)
- Differential phosphorylation, localization, and function of distinct alpha 1 subunits of neuronal calcium channels. Two size forms for class B, C, and D alpha 1 subunits with different COOH-termini. (1994) (16)
- Neurotoxins as allosteric modifiers of voltage-sensitive sodium channels. (1979) (15)
- Interaction of the synprint site of N-type Ca 2 1 channels with the C 2 B domain of synaptotagmin (1997) (15)
- Phosphorylation of Cav 1 . 2 on S 1928 uncouples the L-type Ca 2 + channel from the b 2 adrenergic receptor (2016) (14)
- Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome (2019) (14)
- The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac CaV1.2 calcium channels (2018) (14)
- Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb (2018) (14)
- Molecular pharmacology of voltage-sensitive sodium channels (1988) (14)
- Deficiency of uncoupler-stimulated adenosine triphosphatase activity in tightly coupled hepatoma mitochondria. (1971) (14)
- The use of thin-layer chromatography on poly(ethyleneimine) cellulose to facilitate assays of ATP-ADP exchange, ATP-Pi exchange, adenylate kinase, and nucleoside diphosphokinase activity. (1979) (14)
- Altered short-term synaptic plasticity and reduced muscle strength in mice with impaired regulation of presynaptic CaV2.1 Ca2+ channels (2016) (14)
- Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-α-benzoate binding in vitro (1991) (14)
- Interaction of Presynaptic Calcium channels with SNARE Proteins in Neurotransmitter Release (1999) (14)
- Phosphorylation sites in the Hook domain of CaVβ subunits differentially modulate CaV1.2 channel function. (2015) (14)
- Molecular Determinants of Modulation of CaV2.1 Channels by Visinin-like Protein 2* (2011) (13)
- Detection of marine toxins using reconstituted sodium channels. (1995) (13)
- Voltage-Gated Na+ Channels (2012) (13)
- Molecular mechanisms of inactivation and modulation of sodium channels. (1994) (13)
- Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src (2014) (12)
- Painful Channels (2006) (12)
- Cardiac sodium channel (2020) (12)
- Voltage-Gated Sodium Channels: Structure, Function, and Pathophysiology (2013) (12)
- The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation (2019) (11)
- Structure and modulation of voltage-sensitive sodium and calcium channels. (1990) (11)
- Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective. (2017) (11)
- Palmitylation , Sulfation , and Glycosylation of the a Subunit of the Sodium Channel (11)
- Interactions of neurotoxins with the action potential NA + ionophore. (1976) (11)
- Sodium channels in electrically excitable cells (1982) (10)
- Molecular properties of voltage-sensitive calcium channels. (1989) (10)
- Stabilization of a sodium channel state with high affinity for saxitoxin by intramolecular cross-linking. Evidence for allosteric effects of saxitoxin binding. (1988) (10)
- Circadian Regulation of Sleep in a Pre-Clinical Model of Dravet Syndrome: Dynamics of Sleep Stage and Siesta Re-entrainment. (2019) (10)
- Functional Reconstitution of Purified Sodium Channels from Brain in Planar Lipid Bilayers a (1986) (10)
- Cav 1 . 3 channels produce persistent calcium sparklets , but Cav 1 . 2 channels are responsible for sparklets in mouse arterial smooth muscle (2007) (9)
- Yeasty brew yields novel calcium channel inhibitor (1998) (9)
- Molecular Properties of neurotoxin receptors sites associated with sodium channels from mammalian brain. (1982) (9)
- Structure and functional reconstitution of the sodium channel from rat brain. (1984) (9)
- High-affinity saxitoxin receptor sites in vertebrate heart. Evidence for sites associated with autonomic nerve endings. (1981) (9)
- Inhibition of Na+ channels by the novel blocker PD85,639. (1993) (9)
- The electroplax sodium channel revealed (1985) (9)
- Introduction: Ion channels in plasma membrane signal transduction (1996) (9)
- A more efficient conditional mouse model of Dravet syndrome: Implications for epigenetic selection and sex-dependent behaviors (2019) (9)
- Helical motion of an S4 voltage sensor revealed by gating pore currents (2010) (9)
- Voltage‐gated Na+ channels and epilepsy (2010) (9)
- Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels (2019) (9)
- Down regulation of sodium channels in nerve terminals of spontaneously epileptic mice (1986) (8)
- Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac CaV1.2 channel (2013) (8)
- Characterization of variant neuroblastoma clones with missing or altered sodium channels. (1982) (8)
- Identification of an α subunit of dihydropyridine-sensitive brain calcium channels (1988) (8)
- Finding Channels (2015) (7)
- Photoaffinity labeling of the receptor site forα-Scorpion toxins on purified and reconstituted sodium channels by a new toxin derivative (1990) (7)
- Electrical Excitability and Ion Channels (2012) (7)
- The Voltage-Sensitive Sodium Channel (1983) (7)
- Genetic analysis of ion channels in vertebrates. (1988) (7)
- Phosphorylation ofthecalcium antagonist receptor ofthevoltage- sensitive calcium channel bycAMP-dependent protein kinase (1985) (6)
- Molecular Properties of Dihydropyridine‐Sensitive Calcium Channels (1988) (6)
- The extracellular matrix component hyaluronic acid supports hippocampal synaptic plasticity by modulating postsynaptic L-type Ca2+ channels. (2010) (6)
- Voltage-gated Ca2+ Channels (2003) (6)
- Analysis of ligand binding specificity of receptor chimeras. (1989) (6)
- IgGs from patients with amyotrophic lateral sclerosis and diabetes target CaVα2δ1 subunits impairing islet cell function and survival (2019) (6)
- P-56 SODIUM CHANNEL MUTATION RESPONSIBLE FOR SAXITOXIN RESISTANCE IN CLAMS INCREASES RISK OF PSP (2006) (6)
- Effects of phosphotungstic acid and silicotungstic acid on respiration and integrity of rat liver mitochondria. (1970) (6)
- Autism-associated mutations in KV7 channels induce gating pore current (2021) (6)
- Na+ channel changes in the growth cone and developing nerve terminal. (1995) (6)
- Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome (2021) (5)
- Voltage-gated sodium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (5)
- 11 Regulation of Ionic Channels (1987) (5)
- [37] Purification of F1 ATPase from rat liver mitochondria (1979) (5)
- Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin (2021) (5)
- The developmental regulation of TTX-sensitive sodium channels in rat skeletal muscle in vivo and in vitro. (1985) (4)
- Na+ channel mutations and epilepsy (2010) (4)
- Structure and functional reconstitution of the voltage-sensitive sodium channel from rat brain. (1983) (4)
- Covalent labeling of the Na+ channel with a photoactivable derivative of scorpion toxin (1980) (4)
- Inhibition of Voltage-Sensitive Sodium Channels by Local Anesthetics and Anticonvulsants A Biochemical and Electrophysiological Analysis (1986) (4)
- Comparison of Molecular Properties of the Voltagek‐Sensitive Ca2+ Channel From Longitudinal Smooth Muscle of Rabbit Ileum With the Channel Purified From Transverse Tubules of Rabbit Skeletal Muscle (1987) (4)
- Diphenylhydantoin inhibition of [3H]-batrachotoxinin A 20-α-benzoate binding to intact rat brain synaptosomes (1982) (4)
- The First 50 Years of Molecular Pharmacology (2015) (3)
- Ion channels (2004) (3)
- Auxiliary Subunits of Voltage-Gated Ion Channels Review (1994) (3)
- Voltage-gated calcium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (3)
- Voltage-Gated Sodium Channels and Electrical Excitability of the Heart (2018) (3)
- Mutations in skeletal muscle (2009) (3)
- Biochemical Studies of Voltage-Gated Ca2+ Channels (2005) (3)
- Molecular properties of voltage-sensitive calcium channels. (1987) (3)
- Expression and purification of the cardiac sodium channel NaV1.5 for cryo-EM structure determination. (2021) (3)
- Sharp-Wave Ripple Frequency and Interictal Epileptic Discharges Increase in Tandem During Thermal Induction of Seizures in a Mouse Model of Genetic Epilepsy (2021) (3)
- Membrane potential dependent binding of scorpion toxin to action potential Na+ channels in electrically excitable neuroblastoma cells (1977) (3)
- Convergent regulation of CaV1.2 channels by direct phosphorylation and by the small GTPase RAD in the cardiac fight-or-flight response (2022) (3)
- Facilitation of Spinal NMDA Receptor Currents by Spillover of Synaptically Released Glycine (2003) (2)
- The Voltage‐Gated Ion Channel Superfamily (2006) (2)
- Neurotoxins as allosteric modifiers of action potential sodium channels (1978) (2)
- Chapter 18 Molecular Properties of Voltage-Sensitive Calcium Channels (1988) (2)
- Molecular properties of voltage sensitive Na+ and Ca++ channels (1991) (2)
- Interaction between batrachotoxin and yohimbine in cultured neuroblastoma cells (1977) (2)
- Voltage-Gated Sodium and Calcium Channels (2020) (2)
- Electrically Excitable Cells (1999) (2)
- Exclusion of the SCN2B gene as candidate for CMT4B (1998) (2)
- Disulfide Locking Reveals Interaction of the Gating Charges with a Negative Charge in the S1 Segment During Activation of the NaChBac Voltage Sensor (2011) (2)
- Abstract 17278: Deletion of Distal C-Terminus of Cav1.2 Channel Leads to Loss Of {beta}-Adrenergic Regulation and Heart Failure in vivo (2010) (2)
- The VGL-chanome (2004) (2)
- Voltage-gated sodium channels (2015) (2)
- Ion Channel Protein Superfamily (2013) (2)
- Calcium channels and synaptic plasticity (2007) (2)
- Voltage-gated calcium channels (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (2)
- Biochemical and allosteric properties of neurotoxin receptor sites associated with voltage-sensitive sodium channels (1980) (1)
- Crystal structure of the NavAb voltage-gated sodium channel (Met221Cys, 2.95 A) (2011) (1)
- Mapping the β-Scorpion Toxin Receptor Site on Voltage-Gated Sodium Channels (2010) (1)
- Chapter 5 Sodium Channels in Neural Cells: Molecular Properties and Analysis of Mutants (1985) (1)
- Structural Modeling of Intermediate States of the Gating Pore of NaChBac (2009) (1)
- Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A) (2012) (1)
- AB16-5: Knock out of the Β2-subunit of voltage-gated sodium channels causes arrhythmias and disarrangement of sodium channel β-subunits in the heart (2006) (1)
- High-Resolution Structural Modeling of Voltage-Dependent Conformational Changes in the Voltage Sensor of NaChBac (2011) (1)
- Open and Closed States of the NaVAb Activation Gate (2017) (1)
- Molecular Determinants for Alpha-Scorpion Toxin Binding to the Resting State of a Voltage Sensor of Brain Sodium Channels (2011) (1)
- Contribution of ATP synthesis from endogenous substrates to the oligomycin-sensitive ADP-ATP exchange activity of rat liver mitoplasts. (1971) (1)
- The effect of denervation on the development of the high affinity saxitoxin receptor in the skeletal muscle (1982) (1)
- for asynchronous neurotransmitter release (2012) (1)
- Purification of F1 ATPase from rat liver mitochondria. (1979) (1)
- CHAPTER 5:Voltage-gated Sodium Channels: Structure, Function, and Molecular Pharmacology (2014) (1)
- Na+ channel regulation, structure, trafficking and sequestration (2015) (1)
- Sodium Channel Structure and Function at Atomic Resolution (2012) (1)
- Na+ uptake associated with activation of nicotinic acetylcholine receptors of cultured muscle cells (1974) (1)
- Voltage-dependent potentiation of the activity of cardiac L-type calcium channel al subunits due to phosphorylation by cAMP-dependent protein kinase ( L-type Ca current / protein phosphorylation / ion channel modulation ) (2005) (1)
- Dihydropyridine receptor of L-type Ca 2 + channels : Identification of binding domains for [ 3 H ] ( + )-PN 200-11 O and [ 3 H ] azidopine within the al subunit JORG STRIESSNIG (1)
- Mapping the Receptor Sites for a β-Scorpion Toxin on the Pore Module in Domain III of Voltage-Gated Sodium Channels (2012) (1)
- Voltage-sensitive sodium and calcium channels (1989) (1)
- Reply to technical comment of M. Jackson (1992) (1)
- MODULATION OF BRAIN SODIUM CHANNELS BY ASSOCIATED RECEPTOR PROTEIN TYROSINE PHOSPHATASE β (2000) (1)
- Broadband Tuning the Voltage Dependence of a Sodium Channel (2020) (1)
- Role of Channel Fluctuations in Ion Transport and Selectivity in Bacterial Sodium Channel NavAb (2017) (1)
- Spatiotemporal Control of Vascular CaV1.2 by α1C S1928 Phosphorylation (2022) (1)
- Voltage-gated calcium channels in GtoPdb v.2021.2 (2021) (1)
- Control of Slow, Use Dependent Inactivation of NaVAb by its C Terminal Tail (2017) (1)
- Initiation and Regulation of Synaptic Transmission by Presynaptic Calcium Channel Signaling Complexes (2008) (1)
- William Catterall, Ph.D., of the University of Washington School of Medicine, wins Bristol-Myers Squibb neuroscience research award. (2003) (1)
- Molecular Components of Voltage-Gated Ion Channels (1999) (0)
- Molecular Basis of Paralytic Neurotoxin Action on Voltage-Sensitive Sodium Channels (1985) (0)
- Figure 2, Action potentials in different brain regions in wild-type, heterozygous, and null mutant neurons in NaV1.1 KO mice (2012) (0)
- cAMP-DEPENDENT PHOSPHORYLATION OF THE L-TYPE CALCIUM CHANNEL: BIOCHEMICAL CHARACTERIZATION AND PHYSIOLOGICAL REGULATION (1995) (0)
- Activation of Na + Ionophore by Neurotoxins 1783 0 (2003) (0)
- Membrane Transport | Voltage-Gated Ca2+ Channels (2021) (0)
- Functional expression and localization of brain Nav11 sodium channel alpha-subunits and auxiliary beta-subunits in single cardiac myocytes (2001) (0)
- Special Topic: Genetic-Analysis Of Voltage-Sensitive Ion Channels: General Introduction (1988) (0)
- Block and Permeation of the Hypokalemic Periodic Paralysis Gating Pore In Nav1.4 Channels (2010) (0)
- Figure 6-2, [Origin of the membrane potential...]. (1999) (0)
- Editorial Board and Contents (2018) (0)
- Figure 4, Model of etidocaine binding to the local anesthetic receptor site formed by transmembrane segments IS6, IIIS6, and IVS6 of the Nav1.2 channel (2012) (0)
- Laboratory project: "Studies of Action Potential and Receptor Ionophores" (1976) (0)
- Molecular cloning of the a-1 subunit of an w-conotoxin-sensitive calcium channel ( cDNA / immunoprecdpitation / dihydropyridine receptor / expression ) (0)
- Myristoylation and Calcium-Binding Proteins (2005) (0)
- Signaling Complex of Calcium/Calmodulin-Dependent Protein Kinase II Associated with the C-Terminal Domain of CaV2.1 Channels (2011) (0)
- High-Resolution Structural Modeling of Ion Channel Pore-Forming Domains Using Rosetta (2010) (0)
- Electrical Phenomena in Excitable Cells (1999) (0)
- CalciumChannelsandShort-term SynapticPlasticity * (2013) (0)
- Instructions to Authors (2006) (0)
- Learning from Nature How to Design Anti-insect Selective Pesticides - Clarification of the Interacting Face between Insecticidal Toxins and their Na-channel Receptors (2010) (0)
- Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811 (2016) (0)
- Mechanisms of sudden cardiac death after adrenergic stress in mouse models of hypertrophic cardiomyopathy (2004) (0)
- Computational design of transmembrane pores (2020) (0)
- Voltage-gated calcium channels (CaV) in GtoPdb v.2021.3 (2021) (0)
- HypoPP mutant with ligand1 (2018) (0)
- Chapter 112 – Voltage-Gated Calcium Channels (2010) (0)
- Membrane Transport | The Ion Channel Protein Superfamily (2020) (0)
- structure of a channel (2021) (0)
- Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β -Scorpion Toxin *,S (2008) (0)
- Crystal structure of the NavAb voltage-gated sodium channel in a closed conformation (2017) (0)
- Muscarinic Acetylcholine Receptors in Developing Chick Heart 8693 (2002) (0)
- Molecular Mechanisms of Sodium Channel Inactivation and Block by Local Anesthetics (1996) (0)
- High-level expression of voltage-gated sodium channels in thymidine-arrested human embryonic kidney cells. (2023) (0)
- Cardiac sodium channel with flecainide (2020) (0)
- Molecular properties of Na+ and Ca2+ channels (1992) (0)
- 0 C Molecular Basis of Paralytic Neurotoxin Action on I Voltage-Sensitive Sodium Channels Annual Report (0)
- Molecular pharmacology of the sodium channel of mammalian brain (1984) (0)
- NavAb voltage-gated sodium channel, residues 1-226, crystallized in the presence of Class 1B Anti-arrhythmic drug Lidocaine (2018) (0)
- Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac CaV1.2 calcium channel (2023) (0)
- " I-00 SMolecular Basis of Paralytic Neurotoxin Action on Voltage-Sensitive Sodium Channels o • Annual Summary Report (0)
- Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV (2020) (0)
- Colocalization Of RyR And Cav1.2 In Ventricular Myocytes Is Independent Of The Physical Orientation Of The Cell (2009) (0)
- 110 Immunochemical identification and differential distribution of alternatively spliced forms of the α 1 sub unit of neuronal class a calcium channels (1996) (0)
- Seven books on heart rhythm (2004) (0)
- face of interaction of anti-insect selective toxins with receptor site-3 on voltage-gated sodium channels as a platform for design of novel selective insecticides (2013) (0)
- Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state (2019) (0)
- Table 1, Major Inherited Diseases of Na+ Channels (2012) (0)
- Neuromodulation of Sodium Channels (2009) (0)
- SODIUM CHANNEL IIA INACTIVATION GATE (1999) (0)
- Calcium Channels VBound to the C-terminal Domain of Ca / Calmodulin-dependent Protein Kinase II 2 +-independent Activation of Ca 2 + Ca Neurobiology : (2013) (0)
- Voltage-sensitive sodium and calcium channels: Molecular properties and regulation in skeletal muscle (1989) (0)
- A mutation in segment IVS 6 disrupts fast inactivation of sodium channels ( ion channel / electrical excitabIlity / site-directed mutagenesis (2004) (0)
- Table 1, Functional Impact of Deletion of the NaV1.1 Channel (2012) (0)
- NavAb Voltage-gated Sodium Channel, residues 1-239 (2018) (0)
- Structure-Function Map of the Receptor Site for (cid:1) -Scorpion Toxins in Domain II of Voltage-gated Sodium Channels * □ S (2011) (0)
- NavAb NormoPP mutant (2018) (0)
- Instructions to authors (2004) (0)
- Gating Pore Currents Reveal Sliding Helix Motion of S4 Gating Charges during Activation of NaChBac (2012) (0)
- A Nobel Prize for single channel recording. (1992) (0)
- Crystal structure of voltage-gated sodium channel NavAb G94C/Q150C mutant in the activated state (2019) (0)
- Chapter 4 – Dravet Syndrome: A Sodium Channel Interneuronopathy (2016) (0)
- Regulation and pharmacologic properties of Na+ channels in cultured rat muscle cells (1980) (0)
- Sleepimpairmentandreducedinterneuronexcitabilityinamouse model of Dravet Syndrome (2015) (0)
- Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel NaV1.7. (2023) (0)
- Reviewer list for 2005 (2005) (0)
- Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src (2013) (0)
- Figure 1, Transmembrane organization of Na+ channel subunits (2012) (0)
- Structural basis for gating pore current in periodic paralysis (2018) (0)
- 114 Interaction of N-type calcium channel and synaptic core complex in neurotransmitter release (1997) (0)
- Convergent regulation of Cav1.2 channels by direct phosphorylation and by the small GTPase rad in the cardiac fight-or-flight response. (2023) (0)
- NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206A (2018) (0)
- Role of the Putative Glycines Hinge of Cav3.3 Channels (2011) (0)
- NavAb voltage-gated sodium channel, I217C/F203W (2018) (0)
- Ion Pair Formation During Activation of the NaChBac Voltage Sensor (2009) (0)
- Abstract 3638: AKAP5 is Essential for the Response of Cardiomyocytes to Beta-Adrenergic Stimulation (2009) (0)
- Figure 2, Amino acid sequence similarity of voltage-gated Na+ channel α subunits (2012) (0)
- Cav1.2 Underlies Calcium Sparklets in Arterial Smooth Muscle (2007) (0)
- Functional Properties of Voltage-Gated Ion Channels (1999) (0)
- Catalysis and Selectivity of Na+ Permeation in Bacterial Sodium Channel NaVAb (2014) (0)
- Cardiac Sodium channel with toxin bound (2021) (0)
- Reviewer List for 2004 (2004) (0)
- Fenestrations Control the Resting State Block of a Voltage Gated Sodium Channel (2019) (0)
- Structural basis for severe pain caused by mutations in voltage gated sodium channels Nav1.7. (2023) (0)
- NavAb voltage-gated sodium channel, I217C/F203A (2018) (0)
- Figure 3, Three-dimensional structure of Na+ channels and a related potassium channel (2012) (0)
- Coupling of Channel Fluctuations in Ion Permeation and Selectivity in Bacterial Sodium Channel NavAb (2015) (0)
- Abstract 16750: Phosphodiesterase 4B in the L-Type Calcium Channel Complex Regulates Cardiac Calcium Current and Protects Against Ventricular Arrhythmias (2010) (0)
- Synaptotagmin-7 Enhances Facilitation of Cav2.1 Calcium Channels (2022) (0)
- Voltage-Gated Sodium and Calcium Channels at Atomic Resolution: Structure, Function, and Pharmacology (2018) (0)
- Structural Basis for Ion Conductance and Selectivity in Sodium and Calcium Channels (2015) (0)
- Structural basis for inhibition of the cardiac sodium channel by the atypical antiarrhythmic drug ranolazine (2023) (0)
- Corrigendum to: Circadian regulation of sleep in a pre-clinical model of Dravet syndrome: dynamics of sleep stage and siesta re-entrainment. (2020) (0)
- Crystal structure of the NavAb voltage-gated sodium channel in an open state (2017) (0)
- Figure 3, The unified loss-of-function hypothesis for NaV1.1 genetic epilepsies (2012) (0)
- The Ionic Hypothesis and Rules of Ionic Electricity (1999) (0)
- Reconstitution of PKA-Dependent Modulation of Cardiac Cav1.2 Channels (2010) (0)
- Special Topic: Genetic Analysis of Voltage-Sensitive Ion Channels (1988) (0)
- Presynaptic Cav2.1 channels and short-term plasticity (2008) (0)
- Abstract 1526: Synergistic Autoinhibition of the CaV1.2 Channel by its Proteolytically Cleaved Distal C-Terminus and Mg Bound to the C-Terminal EF-Hand (2008) (0)
- NavAb Voltage-gated Sodium Channel, I217C, in Complex with Class 1C Anti-arrhythmic Flecainide (2018) (0)
- Abstract 171: Localization and Function of Sodium Channel Subtypes in Human Heart (2007) (0)
- A Key Gating Charge Interaction Required for Slow Inactivation of the Navab Bacterial Sodium Channel (2013) (0)
- Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy (2017) (0)
- Rat CNS White Matter Channels and Anoxic Injury in 2+ Axonal L-Type Ca (2015) (0)
- Structure of CavAb in complex with Br-verapamil (2016) (0)
- Instructions to Authors (2009) (0)
- Structure of CavAb in complex with amlodipine (2016) (0)
- Editorial Board (1995) (0)
- Instructions to authors (2008) (0)
- 1 – Voltage-Gated Sodium Channels and Electrical Excitability of the Heart (2014) (0)
- Crystal structure of voltage-gated sodium channel NavAb V100C/Q150C disulfide crosslinked mutant in the activated state (2019) (0)
- Figure 1, Mutations in NaV1.1 channels patients with epilepsy (2012) (0)
- Disulfide Locking Reveals a Closed State Interaction Within the Voltage Sensor of NaChBac (2010) (0)
- Membrane Transport | Voltage-Gated Sodium Channels: Structure, Function, and Pathophysiology (2021) (0)
- Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A) (2016) (0)
- Subunits of Sodium Channels from Vertebrate Brain (2001) (0)
- Cellular / Molecular Modulation of CaV 2 . 1 Channels by the Neuronal Calcium-Binding Protein Visinin-Like Protein-2 (2005) (0)
- Functional and Molecular Interaction of Phenylalkylamines and Dihydropyridines with the Model Calcium Channel CavAb (2016) (0)
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