William Doe
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Australian doctor
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William Doephilosophy Degrees
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Philosophy Biology
William Doe's Degrees
- Doctorate Medicine University of Melbourne
Why Is William Doe Influential?
(Suggest an Edit or Addition)According to Wikipedia, William Fairbank Doe was an Australian-born gastroenterologist who was Provost of the Aga Khan University and professor of medicine and Dean of the University of Birmingham Medical School. From 1993 until 2001 he was the senior editor of the Journal of Gastroenterology and Hepatology. His scientific output includes over 150 scientific research publications in international scientific journals. Since 1999 Doe has been a Fellow of the Academy of Medical Sciences, United Kingdom. He was President of the Gastroenterological Society of Australia from 1989 until 1991.
William Doe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease. (1996) (349)
- Oral budesonide is as effective as oral prednisolone in active Crohn’s disease (1997) (301)
- Depleted mucosal antioxidant defences in inflammatory bowel disease. (1995) (247)
- Functional characterization of a stable, noncytolytic stage of macrophage activation in tumors (1977) (196)
- Macrophage stimulation by bacterial lipopolysaccharides. I. Cytolytic effect on tumor target cells (1978) (169)
- Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propria. (1990) (162)
- Enhanced expression and production of monocyte chemoattractant protein‐1 in inflammatory bowel disease mucosa (1996) (159)
- Enhanced mucosal cytokine production in inflammatory bowel disease. (1992) (154)
- The intestinal immune system. (1989) (146)
- Evidence for complement-binding immune complexes in adult coeliac disease, Crohn's disease, and ulcerative colitis. (1973) (137)
- Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PAI-2 and subsequent effects on extracellular matrix degradation. (1990) (130)
- Dendritic cells, the major antigen-presenting cells of the human colonic lamina propria. (1993) (127)
- Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients. (1995) (124)
- Altered Response of Intestinal Mucosal Fibroblasts to Profibrogenic Cytokines in Inflammatory Bowel Disease (2001) (121)
- Inflammation Location, But Not Type, Determines the Increase in TGF-&bgr;1 and IGF-1 Expression and Collagen Deposition in IBD Intestine (2001) (120)
- Macrophage stimulation by bacterial lipopolysaccharides. II. Evidence for differentiation signals delivered by lipid A and by a protein rich fraction of lipopolysaccharides (1978) (97)
- Antireticulin antibody: Incidence and diagnostic significance (1973) (91)
- Inflammatory cells in solid murine neoplasms. I. TUMOR disaggregation and identification of constituent inflammatory cells (1976) (88)
- RNA-based mutation screening in hereditary nonpolyposis colorectal cancer. (1996) (87)
- Five cases of alpha chain disease (1972) (84)
- Isolation of colonic crypts that maintain structural and metabolic viability in vitro. (1989) (83)
- Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene* (1996) (83)
- The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it (2001) (76)
- Mediation systems in bacterial lipopolysaccharide-induced hypotension and disseminated intravascular coagulation. I. The role of complement (1975) (72)
- Immunohistochemical Characterisation of Macrophages in Human Liver and Gastrointestinal Tract: Expression of CD4, HLA‐DR, OKM1, and the Mature Macrophage Marker 25F9 in Normal and Diseased Tissue (1987) (72)
- Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family. (1995) (70)
- Isolation and preliminary characterization of human intestinal macrophages. (1983) (67)
- Intrajejunal volatile fatty acids in the stagnant loop syndrome (1972) (63)
- Macrophage stimulation by bacterial lipopolysaccharides. III. Selective unresponsiveness of C3H/HeJ macrophages to the lipid A differentiation signal. (1979) (63)
- Chemokines in Inflammatory Bowel Disease Mucosa: Expression of RANTES, Macrophage Inflammatory Protein (MIP)‐1&agr;, MIP‐1&bgr;, and &ggr;‐Interferon‐Inducible Protein‐10 by Macrophages, Lymphocytes, Endothelial Cells, and Granulomas (1996) (63)
- Number of macrophages and distribution of mitotic activity in regressing and progressing Moloney sarcomas. (1976) (62)
- Distribution of human colonic dendritic cells and macrophages (1996) (62)
- Immunodiagnosis of alpha chain disease. (1979) (60)
- Lymphokine-activated and natural killer cell activity in human intestinal mucosa. (1985) (60)
- The G cells in pernicious anaemia (1971) (59)
- Subepithelial collagen in intestinal malabsorption. (1975) (57)
- Coeliac disease, vasculitis, and cryoglobulinaemia (1972) (49)
- Human urokinase receptor expression is inhibited by amiloride and induced by tumor necrosis factor and phorbol ester in colon cancer cells (1994) (46)
- Urokinase‐type plasminogen activator in colorectal carcinomas and adenomatous polyps: Quantitative expression of active and proenzyme (1988) (45)
- Expression of urokinase‐type plasminogen activator receptor in hepatocellular carcinoma (1997) (45)
- Dextran sodium sulphate‐induced colitis activity varies with mouse strain but develops in lipopolysaccharide‐unresponsive mice (1999) (45)
- A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor. (1999) (43)
- 5-Aminosalicylic acid prevents oxidant mediated damage of glyceraldehyde-3-phosphate dehydrogenase in colon epithelial cells (1999) (43)
- Alpha chain disease clinicopathological features and relationship to so-called Mediterranean lymphoma. (1975) (40)
- Protein carbonyl formation on mucosal proteins in vitro and in dextran sulfate-induced colitis. (1999) (38)
- Ulcerative colitis--a disease characterised by the abnormal colonic epithelial cell? (1988) (37)
- Urokinase type plasminogen activator receptor expression in colorectal neoplasms (1998) (36)
- Chronic inflammatory bowel disease--increased plasminogen activator secretion by mononuclear phagocytes. (1982) (36)
- The medical care practitioner: developing a physician assistant equivalent for the United Kingdom (2006) (35)
- Alpha-chain Disease with Clinical, Immunological, and Histological Recovery (1974) (34)
- Salicylate hydroxylation as an indicator of hydroxyl radical generation in dextran sulfate-induced colitis. (1998) (30)
- Minactivin expression in human monocyte and macrophage populations. (1985) (26)
- Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice: natural killer cell activity in cultured spleen leukocytes concomitant with T-cell-dependent immune interferon production (1979) (24)
- Monoclonal antibodies inhibitory to human plasmin. Definitive demonstration of a role for plasmin in activating the proenzyme of urokinase-type plasminogen activator. (1986) (24)
- Studies on the nature and significance of connective tissue antibodies in adult coeliac disease and Crohn's disease (1974) (23)
- Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post‐transcription levels in colon cancer cells (1995) (23)
- Biochemical and morphological studies on human jejunal mucosa maintained in culture. (1976) (22)
- Proenzyme to urokinase-type plasminogen activator in human colon cancer: in vitro inhibition by monocyte minactivin after proteolytic activation. (1987) (22)
- Plasminogen activator inhibitor 2 (PAI-2) is not inactivated by exposure to oxidants which can be released from activated neutrophils. (1990) (21)
- The epidemiology of sarcoidosis (1969) (20)
- Immunopathology of coeliac disease. (1977) (20)
- Lysis of colonic epithelial cells by allogeneic mononuclear and lymphokine activated killer cells derived from peripheral blood and intestinal mucosa: evidence against a pathogenic role in inflammatory bowel disease. (1988) (18)
- Preparation and Characterization of Human Bone Marrow‐Derived Macrophages (1985) (18)
- Proceedings: Collagenous basement membrane thickening in jejunal biopsies from patients with adult coeliac disease. (1974) (16)
- Oral budesonide competes favourably with prednisolone in active Crohn's disease (1995) (16)
- Expression of urokinase‐type plasminogen activator receptor and plasminogen activator inhibitor‐1 in gastric cancer (1998) (15)
- An immunological study of adult coeliac disease. (1972) (15)
- Amiloride modulates urokinase gene expression at both transcription and post-transcription levels in human colon cancer cells (1995) (14)
- Cell associated urokinase activity and colonic epithelial cells in health and disease. (1991) (14)
- An overview of intestinal immunity and malabsorption. (1979) (14)
- Colonic Antioxidant Status in Dextran Sulfate‐Induced Colitis in Mice (1997) (13)
- The secretory immune system of the intestine. (1972) (13)
- CASE REPORT: Antibiotic‐associated haemorrhagic colitis (1998) (12)
- Occupancy of the cancer cell urokinase receptor (uPAR): effects of acid elution and exogenous uPA on cell surface urokinase (uPA). (1992) (12)
- Role of macrophages in cellular defence (1988) (12)
- Chromosome 2p linkage analysis in hereditary non‐polyposis colon cancer (1995) (10)
- Acute diarrhoea in adults. (1981) (9)
- Two Brothers with Congenital Pancreatic Exocrine Insufficiency, Neutropenia and Dysgammaglobulinaemia (1973) (6)
- Macrophage Stimulation by Bacterial Lipopolysaccharides (1979) (6)
- Isolation of plasma membrane from human blood monocytes. Subcellular fractionation and marker distribution. (1985) (6)
- Antibiotic-associated haemorrhagic colitis. (1998) (6)
- Coeliac disease, vasculitis, and cryoglobulinaemia. (1972) (6)
- Distribution of human colonic dendritic cells and macrophages--functional implications. (1995) (6)
- MACROPHAGES IN REGRESSING AND PROGRESSING MOLONEY SARCOMAS (1976) (5)
- Radiological and histological findings in six patients with alpha-chain disease. (1976) (5)
- A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR) (2004) (4)
- Depletion of nuetrophils decreases disease severity and mortality in a mouse model of ulcerative colitis (1995) (4)
- Lysosomal acid hydrolase activity in intestinal biopsies from control subjects and patients with coeliac disease. (1973) (3)
- Increased circulating T alpha lymphocyte population in bronchogenic and colonic carcinoma. (1981) (3)
- TheG cells inpernicious anaemia (1971) (2)
- Characterization of an antiserum specific for the Fabalpha fragment. Its use for detection of alpha-heavy chain disease protein by immunoselection. (1979) (2)
- Evidence for circulating immune complexes in inflammatory bowel disease and adult coeliac disease. (1973) (2)
- The relative occurrence of macrophages in regressing and progressing moloney sarcomas. Abstr. (1975) (1)
- Proceedings: Use of an improved jejunal culture system for the study of normal and coeliac mucosa. (1975) (1)
- Proceedings: Antigen binding cells in rabbit Peyer's patches after intestinal immunisation. (1976) (1)
- Urokinase receptor genotypes in colorectal cancer. (1998) (1)
- Gene symbol: MLH1. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (1)
- Enrichment and Characterization of Dendritic Cells From the Lamina Propria of Murine Intestine (1988) (1)
- Theories of vaccination for Helicobacter pylori (1996) (1)
- Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Proceedings: In vitro culture of human jejunal mucosa: enzyme changes in tissue and culture medium. (1973) (0)
- Mucosal macrophages and dendritic cells (1990) (0)
- Gene symbol: MLH1. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Immunodiagnosis of alpha heavy chain protein (αHCP) in immunoproliferative small intestinal disease (IPSID) (1978) (0)
- Immunohistochemical Characterization of Macrophages in the Intestinal-Mucosa Using the Mature Macrophage Antigen 25F9 (1986) (0)
- The Distribution of the 25F9 Macrophage-Specific Antigen in Human Gastrointestinal-Tract (1985) (0)
- Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Bacterial factors in inflammatory bowel disease pathogenesis (2000) (0)
- PATHOGENESIS OF CHRONIC INTESTINAL INFLAMMATION—IDENTIFICATION OF TWO ENDOTOXIN SIGNALS WHICH INDUCE LYSOSOMAL ENZYME RELEASE FROM EXUDATE BUT NOT RESTING MACROPHAGES (1980) (0)
- Disaggregation and identification of constituent inflammatory cells. (1976) (0)
- Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Inhibition of Mouse Intestinal Lamina Propria and Peyers Patch Antigen-Presenting Cell-Activity by Lamina Propria Macrophages (1987) (0)
- Development of an antiserum recognising Fdα determinants of IgA (1978) (0)
- Lipopolysaccharide-induced macrophage activation. Abstr. (1976) (0)
- chemoattractant protein-i in inflammatory bowel disease mucosa (1996) (0)
- The intestinal immune system (2006) (0)
- Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer. (2005) (0)
- Gene symbol: hMSH2. Disease: hereditary nonpolyposis colorectal cancer. (2005) (0)
- Characterization of an Antiserum Specific for the Fabα Fragment (1979) (0)
- 5-Aminosalicylic acid but not immunosuppressive therapies prevent oxidant-mediated inhibition of glyceraldehyde-3-phosphate dehydrogenase (1998) (0)
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