William H. Gerwick
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Researcher ORCID ID = 0000-0003-1403-4458
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William H. Gerwickchemistry Degrees
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William H. Gerwickbiology Degrees
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Chemistry Biology
William H. Gerwick's Degrees
- PhD Pharmacology University of California, San Diego
- Bachelors Chemistry University of California, San Diego
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(Suggest an Edit or Addition)William H. Gerwick's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking (2016) (2091)
- Minimum Information about a Biosynthetic Gene cluster. (2015) (600)
- Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. (2012) (550)
- Marine natural products as anticancer drugs. (2005) (549)
- Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. (2004) (429)
- Molecular networking as a dereplication strategy. (2013) (415)
- Metabolic engineering of lipid catabolism increases microalgal lipid accumulation without compromising growth (2013) (368)
- Retrospective analysis of natural products provides insights for future discovery trends (2017) (307)
- The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria (1993) (300)
- Structure of Curacin A, a Novel Antimitotic, Antiproliferative and Brine Shrimp Toxic Natural Product from the Marine Cyanobacterium Lyngbya majuscula (1994) (283)
- The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters. (2007) (277)
- Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula. (2004) (272)
- Marine natural products as novel antioxidant prototypes. (2003) (256)
- Biologically active secondary metabolites from marine cyanobacteria. (2010) (231)
- Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells. (1998) (229)
- Moorea producens gen. nov., sp. nov. and Moorea bouillonii comb. nov., tropical marine cyanobacteria rich in bioactive secondary metabolites. (2012) (219)
- The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit. (2002) (206)
- Biosynthetic origin of natural products isolated from marine microorganism–invertebrate assemblages (2008) (193)
- The Identification and Characterization of the Marine Natural Product Scytonemin as a Novel Antiproliferative Pharmacophore (2002) (187)
- Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase. (2004) (184)
- Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp. (2008) (174)
- Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. (1998) (172)
- Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra (2020) (170)
- Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp. (2007) (159)
- Metamorphic enzyme assembly in polyketide diversification (2009) (150)
- Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. (2008) (149)
- Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly. (2002) (145)
- Survey of NMR experiments for the determination of nJ(C,H) heteronuclear coupling constants in small molecules (2001) (145)
- One‐ and two‐dimensional gradient‐selected HSQMBC NMR experiments for the efficient analysis of long‐range heteronuclear coupling constants (2000) (144)
- Oxylipin Profiling of the Hypersensitive Response in Arabidopsis thaliana (2006) (143)
- Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula. (1996) (142)
- Characterization of Cyanobacterial Hydrocarbon Composition and Distribution of Biosynthetic Pathways (2014) (142)
- Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis. (2011) (139)
- Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula. (2007) (136)
- The chemical ecology of cyanobacteria. (2012) (135)
- Nitrogen-containing metabolites from marine cyanobacteria. (2001) (134)
- Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage (2011) (134)
- Scytonemin-a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases (2002) (133)
- Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A. (2009) (131)
- Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida. (2008) (128)
- Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. (2015) (122)
- Ichthyotoxic and cytotoxic metabolites of the tropical brown alga Stypopodium zonale (Lamouroux) Papenfuss (1981) (119)
- Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula. (1999) (118)
- Chromones from the endophytic fungus Pestalotiopsis sp. isolated from the chinese mangrove plant Rhizophora mucronata. (2009) (117)
- Antillatoxin: An Exceptionally Ichthyotoxic Cyclic Lipopeptide from the Tropical Cyanobacterium Lyngbya majuscula (1995) (116)
- Oxo-Phytodienoic Acid-Containing Galactolipids in Arabidopsis: Jasmonate Signaling Dependence1[W][OA] (2007) (115)
- On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies. (2005) (115)
- Synergistic allelochemicals from a freshwater cyanobacterium (2010) (114)
- Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells. (2010) (114)
- Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula. (2007) (111)
- GNAT-Like Strategy for Polyketide Chain Initiation (2007) (108)
- Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. (2008) (108)
- Promotive effects of alginate-derived oligosaccharide on maize seed germination (2004) (107)
- Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria. (2005) (107)
- Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. (2006) (106)
- Anti-oxidation of agar oligosaccharides produced by agarase from a marine bacterium (2004) (105)
- Structure, Synthesis, and Biological Properties of Kalkitoxin, a Novel Neurotoxin from the Marine Cyanobacterium Lyngbya majuscula (2000) (105)
- cis,cis- and trans,trans-ceratospongamide, new bioactive cyclic heptapeptides from the Indonesian red alga Ceratodictyon spongiosum and symbiotic sponge Sigmadocia symbiotica. (2000) (105)
- Identification of the cellular site of polychlorinated peptide biosynthesis in the marine sponge Dysidea (Lamellodysidea) herbacea and symbiotic cyanobacterium Oscillatoria spongeliae by CARD-FISH analysis (2005) (103)
- Drug Discovery from Marine Microbes (2013) (103)
- Preparation and structure elucidation of alginate oligosaccharides degraded by alginate lyase from Vibro sp. 510. (2004) (99)
- Characterization of a novel β-agarase from marine Alteromonas sp. SY37–12 and its degrading products (2005) (99)
- Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula (2011) (99)
- Structural studies on κ-carrageenan derived oligosaccharides (2002) (98)
- Carbocyclic Oxylipins of Marine Origin (1993) (98)
- Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis. (2008) (98)
- The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. (2010) (97)
- Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses (2011) (97)
- Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophoramucronata. (2009) (96)
- Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway. (2010) (95)
- Evolved Diversification of a Modular Natural Product Pathway: Apratoxins F and G, Two Cytotoxic Cyclic Depsipeptides from a Palmyra Collection of Lyngbya bouillonii (2010) (95)
- Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships. (2012) (94)
- Structure and biosynthesis of marine algal oxylipins. (1994) (94)
- Lophocladines, bioactive alkaloids from the red alga Lophocladia sp. (2006) (94)
- In vitro antioxidative activities of three marine oligosaccharides (2007) (94)
- Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels (2001) (93)
- Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. (2013) (91)
- The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8 (2008) (90)
- Imaging mass spectrometry of natural products. (2009) (90)
- Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. (2006) (90)
- Dereplication and De Novo Sequencing of Nonribosomal Peptides (2009) (90)
- Five chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. nov. (Oscillatoriales, Cyanoprokaryota) (2013) (90)
- Hormothamnione, a novel cytotoxic styrylchromone from the marine cyanophyte grunow (1986) (89)
- Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera. (2011) (89)
- Lyngbyabellin B, a toxic and antifungal secondary metabolite from the marine cyanobacterium Lyngbya majuscula. (2000) (89)
- 6-Desmethoxyhormothamnione, a new cytotoxic styrylchromone from the marine cryptophyte Chrysophaeum taylori. (1989) (88)
- The Natural Products Chemistry of Cyanobacteria (2010) (87)
- Sharing and community curation of mass spectrometry data with GNPS (2016) (87)
- The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β‐Epoxyketone Warhead from a Marine Cyanobacterium (2012) (85)
- Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. (2010) (85)
- Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula. (2010) (84)
- Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues. (1995) (84)
- New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria. (2009) (84)
- Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds. (2010) (84)
- Heparin mapping using heparin lyases and the generation of a novel low molecular weight heparin. (2011) (82)
- Antibiotic activity of lipid-soluble extracts from Caribbean marine algae (1987) (82)
- Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. (2009) (82)
- Optimization study on the hydrogen peroxide pretreatment and production of bioethanol from seaweed Ulva prolifera biomass. (2016) (81)
- The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria. (2010) (81)
- Oxylipin metabolism in the red alga Gracilariopsis lemaneiformis: mechanism of formation of vicinal dihydroxy fatty acids. (1991) (80)
- Structure and absolute stereochemistry of phormidolide, a new toxic metabolite from the marine cyanobacterium Phormidium sp. (2002) (80)
- Belamide A, a new antimitotic tetrapeptide from a Panamanian marine cyanobacterium (2006) (80)
- Grenadadiene and grenadamide, cyclopropyl-containing fatty acid metabolites from the marine cyanobacterium Lyngbya majuscula. (1998) (80)
- Oceans and human health: risks and remedies from the seas (2008) (78)
- Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. (2009) (78)
- Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. (2008) (78)
- Antillatoxin and kalkitoxin, ichthyotoxins from the tropical cyanobacterium Lyngbya majuscula, induce distinct temporal patterns of NMDA receptor-mediated neurotoxicity. (1999) (77)
- Preparation and anti-influenza A virus activity of κ-carrageenan oligosaccharide and its sulphated derivatives (2012) (77)
- Conformational switch triggered by α-ketoglutarate in a halogenase of curacin A biosynthesis (2010) (77)
- The guineamides, novel cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. (2003) (77)
- Screening cultured marine microalgae for anticancer-type activity (1994) (77)
- The wewakpeptins, cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. (2005) (77)
- Organization, Evolution, and Expression Analysis of the Biosynthetic Gene Cluster for Scytonemin, a Cyanobacterial UV-Absorbing Pigment (2009) (76)
- Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria. (2009) (76)
- Exploiting Adaptive Laboratory Evolution of Streptomyces clavuligerus for Antibiotic Discovery and Overproduction (2012) (75)
- Antileishmanial constituents of the Panamanian endophytic fungus Edenia sp. (2008) (73)
- Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya. (2011) (72)
- Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel. (2016) (72)
- A Convolutional Neural Network-Based Approach for the Rapid Characterization of Molecularly Diverse Natural Products. (2020) (71)
- Structure and protective effect of exopolysaccharide from P. Agglomerans strain KFS-9 against UV radiation. (2007) (70)
- Sequence analysis of alginate-derived oligosaccharides by negative-ion electrospray tandem mass spectrometry (2006) (70)
- Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica. (2009) (69)
- Somamides A and B, two new depsipeptide analogues of dolastatin 13 from a Fijian cyanobacterial assemblage of Lyngbya majuscula and Schizothrix species. (2001) (69)
- High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium. (2013) (68)
- Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis (2011) (67)
- Total structure of hormothamnin A, a toxic cyclic undecapeptide from the tropical marine cyanobacterium Hormothamnion enteromorphoides (1992) (67)
- MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus (2013) (66)
- Somocystinamide A, a novel cytotoxic disulfide dimer from a Fijian marine cyanobacterial mixed assemblage. (2002) (66)
- Palmyrolide A, an unusually stabilized neuroactive macrolide from Palmyra Atoll cyanobacteria. (2010) (65)
- Carmabins A and B, new lipopeptides from the Caribbean cyanobacterium Lyngbya majuscula. (1998) (65)
- Phylogenetic Inferences Reveal a Large Extent of Novel Biodiversity in Chemically Rich Tropical Marine Cyanobacteria (2013) (64)
- Hermitamides A and B, toxic malyngamide-type natural products from the marine cyanobacterium Lyngbya majuscula. (2000) (64)
- Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium. (2011) (63)
- Handbook of Marine Natural Products (2012) (63)
- Antitumor Activity of Hierridin B, a Cyanobacterial Secondary Metabolite Found in both Filamentous and Unicellular Marine Strains (2013) (62)
- Eicosanoids and Related Compounds from Marine Algae (1993) (62)
- Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea (2017) (62)
- Lyngbouilloside, a novel glycosidic macrolide from the marine cyanobacterium Lyngbya bouillonii. (2002) (62)
- Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula. (1998) (62)
- Changes in secondary metabolic profiles of Microcystis aeruginosa strains in response to intraspecific interactions. (2016) (61)
- Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity (2017) (60)
- Antillatoxin B, a neurotoxic lipopeptide from the marine cyanobacterium Lyngbya majuscula. (2001) (60)
- Biosynthesis of the marine cyanobacterial metabolite barbamide. 1. Origin of the trichloromethyl group (1998) (60)
- Sequence determination of sulfated carrageenan-derived oligosaccharides by high-sensitivity negative-ion electrospray tandem mass spectrometry. (2006) (60)
- Antitumour activities of alginate-derived oligosaccharides and their sulphated substitution derivatives (2004) (60)
- The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones. (2011) (60)
- Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. (2006) (59)
- Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. (2013) (59)
- Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms. (2009) (59)
- Characterization of the initial enzymatic steps of barbamide biosynthesis. (2006) (59)
- Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula. (2002) (59)
- Biosynthetic Pathway and Origin of the Chlorinated Methyl Group in Barbamide and Dechlorobarbamide, Metabolites from the Marine Cyanobacterium Lyngbya majuscula (2000) (58)
- Isolation and structure of spatol, a potent inhibitor of cell replication from the brown seaweed Spatoglossum schmittii (1980) (58)
- A novel low-temperature resistant alkaline lipase from a soda lake fungus strain Fusarium solani N4-2 for detergent formulation (2009) (57)
- Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium. (2017) (57)
- Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells (2017) (57)
- The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons. (2005) (57)
- Marine Natural Products into the Future (2012) (57)
- Yanucamides A and B, two new depsipeptides from an assemblage of the marine cyanobacteria Lyngbya majuscula and Schizothrix species. (2000) (56)
- THREE NEW MALYNGAMIDES FROM THE MARINE CYANOBACTERIUM LYNGBYA MAJUSCULA (1997) (56)
- Chemical variation in the tropical seaweed Stypopodium zonale (Dictyotaceae) (1985) (56)
- Viequeamide A, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium. (2012) (56)
- Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. (2003) (55)
- The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L. (2014) (55)
- Preparation of low-molecular-weight polyguluronate sulfate and its anticoagulant and anti-inflammatory activities (2007) (55)
- STRUCTURAL, CHEMICAL AND ECOLOGICAL STUDIES ON IRIDESCENCE IN IRIDAEA (RHODOPHYTA) 1 (1977) (55)
- Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. (2015) (55)
- Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, targeting CD4 in lymphocytes. (2004) (54)
- A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A. (2010) (54)
- Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product. (2012) (54)
- Neurotoxic meroditerpenoids from the tropical marine brown alga Stypopodium flabelliforme. (2005) (54)
- Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii. (2012) (54)
- Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii. (2010) (53)
- Quantitative molecular networking to profile marine cyanobacterial metabolomes (2013) (53)
- Combined LC-MS/MS and Molecular Networking Approach Reveals New Cyanotoxins from the 2014 Cyanobacterial Bloom in Green Lake, Seattle. (2015) (52)
- Crossbyanols A-D, toxic brominated polyphenyl ethers from the Hawai'ian bloom-forming Cyanobacterium Leptolyngbya crossbyana. (2010) (52)
- Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction. (2012) (51)
- Novel oxylipins from the temperate red alga polyneura latissima: Evidence for an arachidonate 9(S)-lipoxygenase (1997) (51)
- Microbiota of Healthy Corals Are Active against Fungi in a Light-Dependent Manner (2014) (51)
- Isolation and structure of five lyngbyabellin derivatives from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula (2005) (51)
- Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61 (2016) (50)
- Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula. (2009) (50)
- Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research (2017) (50)
- Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. (2012) (49)
- 16S rRNA GENE HETEROGENEITY IN THE FILAMENTOUS MARINE CYANOBACTERIAL GENUS LYNGBYA 1 (2010) (49)
- Biosynthesis of vicinal dihydroxy fatty acids in the red alga Gracilariopsis lemaneiformis: identification of a sodium-dependent 12-lipoxygenase and a hydroperoxide isomerase. (1993) (49)
- Isolation and structure of constanolactones A and B, new cyclopropyl hydroxy-eicosanoids from the temperate red alga constantinea simplex (1990) (49)
- Preparation, purification and characterization of alginate oligosaccharides degraded by alginate lyase from Pseudomonas sp. HZJ 216. (2011) (49)
- Giant Marine Cyanobacteria Produce Exciting Potential Pharmaceuticals (2008) (49)
- Two new malyngamides from a Madagascan Lyngbya majuscula. (2000) (48)
- Chemical Constituents of the New Endophytic Fungus Mycosphaerella sp. nov. and Their Anti-parasitic Activity (2011) (48)
- Stypotriol and stypoldione; ichthyotoxins of mixed biogenesis from the marine alga ☆ (1979) (48)
- The influence of molecular mass of sulfated propylene glycol ester of low-molecular-weight alginate on anticoagulant activities (2007) (48)
- Influence of Lipid-Soluble Gating Modifier Toxins on Sodium Influx in Neocortical Neurons (2008) (48)
- Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula. (2010) (48)
- Structure and stereochemistry of constanolactones A-G, lactonized cyclopropyl oxylipins from the red marine alga Constantinea simplex (1994) (47)
- Crystal Structure of the ECH2 Catalytic Domain of CurF from Lyngbya majuscula (2007) (47)
- New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge Theonella swinhoei. (2014) (47)
- Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii. (2009) (46)
- Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation (2017) (45)
- DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii. (2006) (45)
- Malyngamide H, an ichthyotoxic amide possessing a new carbon skeleton from the Caribbean cyanobacterium Lyngbya majuscula. (1995) (45)
- Kalkipyrone, a toxic gamma-pyrone from an assemblage of the marine cyanobacteria Lyngbya majuscula and Tolypothrix sp. (1998) (44)
- New diffusion-edited NMR experiments to expedite the dereplication of known compounds from natural product mixtures. (2000) (44)
- Structure of malhamensilipin A, an inhibitor of protein tyrosine kinase, from the cultured chrysophyte Poterioochromonas malhamensis. (1994) (44)
- Phenolic lipids from related marine algae of the order dictyotales (1982) (44)
- Bissubvilides A and B, Cembrane-Capnosane Heterodimers from the Soft Coral Sarcophyton subviride. (2016) (43)
- Evaluation of the efficiency of three different solvent systems to extract triterpene saponins from roots of Panax quinquefolius using high-performance liquid chromatography. (2004) (43)
- Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula. (2003) (43)
- Curacins B and C, new antimitotic natural products from the marine cyanobacterium Lyngbya majuscula (1995) (43)
- Malyngamide I from the tropical marine cyanobacterium Lyngbya majuscula and the probable structure revision of stylocheilamide (1995) (43)
- Biosynthesis of conjugated triene-containing fatty acids by a novel isomerase from the red marine alga Ptilota filicina. (1994) (43)
- Diverse secondary metabolites from a Puerto Rican collection of Lyngbyamajuscula. (2003) (43)
- Assessment of Anabaena sp. Strain PCC 7120 as a Heterologous Expression Host for Cyanobacterial Natural Products: Production of Lyngbyatoxin A. (2016) (43)
- Probing marine natural product defenses with DESI-imaging mass spectrometry (2009) (42)
- Mycoleptodiscins A and B, cytotoxic alkaloids from the endophytic fungus Mycoleptodiscus sp. F0194. (2013) (42)
- Marine natural products as potential anti-tubercular agents. (2019) (42)
- 3-(Hydroxyacetyl)indole, a plant growth regulator from the oregon red alga Prionitis lanceolata (1990) (42)
- Unique marine derived cyanobacterial biosynthetic genes for chemical diversity. (2016) (41)
- Oxylipins from marine invertebrates (1993) (41)
- Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium Associated with the Coibamide Producer (2015) (41)
- Two new icosapentaenoic acids from the temperate red seaweedPtilota filicina J. Agardh (1987) (41)
- Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. (2012) (41)
- ABSOLUTE CONFIGURATION OF CURACIN A, A NOVEL ANTIMITOTIC AGENT FROM THE TROPICAL MARINE CYANOBACTERIUM LYNGBYA MAJUSCULA (1995) (41)
- Spatane diterpenoids from the tropical marine alga Stoechospermum marginatum (Dictyotaceae) (1981) (41)
- Ptilodene, a novel icosanoid inhibitor of 5-lifoxygenase and Na+/K+ ATPase from the red marine alga ptilota FilicinaJ. Agardh (1988) (39)
- Antiparasitic and Anticancer Constituents of the Endophytic Fungus Aspergillus sp. strain F1544 (2012) (38)
- Dynamics of antibacterial activity in three species of Caribbean marine algae as a function of habitat and life history (1996) (38)
- Promotive effects of alginate-derived oligosaccharides on the inducing drought resistance of tomato (2009) (38)
- Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect. (2011) (38)
- 5-Lipoxygenase-derived oxylipins from the red alga Rhodymenia pertusa. (2000) (38)
- Structure and biosynthesis of novel conjugated polyene fatty acids from the marine green algaAnadyomene stellata (1995) (38)
- Biosynthesis-assisted structural elucidation of the bartolosides, chlorinated aromatic glycolipids from cyanobacteria. (2015) (38)
- Cannabinomimetic lipid from a marine cyanobacterium. (2011) (37)
- MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. (2019) (37)
- Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β. (2018) (37)
- Enzymatic production of (-)-indolactam V by LtxB, a cytochrome P450 monooxygenase. (2010) (36)
- Total Synthesis and Structure-Activity Relationship of Glycoglycerolipids from Marine Organisms (2014) (36)
- Novel cytotoxic peptides from the tropical marine cyanobacteriumHormothamnion enteromorphoides 1. Discovery, isolation and initial chemical and biological characterization of the hormothamnins from wild and cultured material (1989) (36)
- The inhibitory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells. (2011) (35)
- Peyssonenynes a and B, novel enediyne oxylipins with DNA methyl transferase inhibitory activity from the red marine alga peyssonneliacaulifera. (2004) (35)
- Unprecedented oxylipins from the marine green alga Acrosiphonia coalita. (1993) (35)
- Extraction, isolation and structural characterization of polysaccharides from a red alga Gloiopeltis furcata (2010) (35)
- Preparation and characterization of guluronic acid oligosaccharides degraded by a rapid microwave irradiation method. (2013) (35)
- Heparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages. (2011) (35)
- Structure revision and absolute configuration of malhamensilipin A from the freshwater chrysophyte Poterioochromonas malhamensis. (2010) (35)
- Effects of polymannuronate on performance, antioxidant capacity, immune status, cecal microflora, and volatile fatty acids in broiler chickens. (2015) (35)
- Antibacterial activity of lyase-depolymerized products of alginate (2005) (34)
- Biogenesis and biological function of marine algal oxylipins. (1999) (34)
- Practical total syntheses of epiquinamide enantiomers. (2006) (34)
- Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula. (2010) (34)
- Isolation of 12-(S)-hepe from the red marine alga murrayella periclados and revision of structure of an acyclic icosanoid from laurencia hybrida. Implications to the biosynthesis of the marine prostanoid hybridalactone (1988) (33)
- Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity (2012) (33)
- Antillatoxin, a Novel Lipopeptide, Enhances Neurite Outgrowth in Immature Cerebrocortical Neurons through Activation of Voltage-Gated Sodium Channels (2010) (33)
- Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens. (2017) (33)
- Minor alkaloids from Guatteria dumetorum with antileishmanial activity. (2006) (33)
- Imaging Mass Spectrometry of Natural Products (2010) (33)
- λ-Carrageenan P32 Is a Potent Inhibitor of Rabies Virus Infection (2015) (32)
- Taveuniamides: new chlorinated toxins from a mixed assemblage of marine cyanobacteria (2004) (32)
- Molluscicidal metabolites from an assemblage of Palmyra Atoll cyanobacteria. (2011) (32)
- Temporal dynamics of natural product biosynthesis in marine cyanobacteria (2011) (32)
- Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. (2019) (32)
- Isorawsonol and related IMP dehydrogenase inhibitors from the tropical green alga Avrainvillea rawsonii. (1994) (32)
- Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity (2015) (32)
- Spatane diterpenoids from the tropical marine algae Spatoglossum schmittii and Spatoglossum howleii (dictyotaceae) (1983) (32)
- Ulvan lyase assisted structural characterization of ulvan from Ulva pertusa and its antiviral activity against vesicular stomatitis virus. (2020) (32)
- Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase. (2016) (31)
- Structural characterization of ulvan extracted from Ulva clathrata assisted by an ulvan lyase. (2020) (31)
- EICOSANOIDS FROM THE TROPICAL RED ALGA MURRAYELLA PERICLADOS (1994) (31)
- Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1) (2016) (31)
- Structure and activity of DmmA, a marine haloalkane dehalogenase (2012) (31)
- Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A (2012) (31)
- Linking bioprospecting with sustainable development and conservation: the Panama case (2007) (31)
- Antifungal Depsidone Metabolites from Cordyceps dipterigena, an Endophytic Fungus Antagonistic to the Phytopathogen Gibberella fujikuroi. (2012) (31)
- 5'-Hydroxyisoavrainvilleol, a new diphenylmethane derivative from the tropical green alga Avrainvillea nigricans. (1987) (31)
- Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria. (2012) (31)
- Nakienones A-C and nakitriol, new cytotoxic cyclic C11 metabolites from an okinawan cyanobacterial (Synechocystis sp.) overgrowth of coral (1995) (31)
- The Phormidolide Biosynthetic Gene Cluster: A trans‐AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide (2016) (31)
- Design of gallinamide A analogs as potent inhibitors of the cysteine proteases human cathepsin L and Trypanosoma cruzi cruzain. (2019) (30)
- Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 alpha subunits (2010) (30)
- Acetylated Chitosan Oligosaccharides Act as Antagonists against Glutamate-Induced PC12 Cell Death via Bcl-2/Bax Signal Pathway (2015) (30)
- Biologically active oxylipins from seaweeds (1993) (30)
- Self-assembled Micelle Loading Cabazitaxel for therapy of Lung Cancer. (2016) (30)
- Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group (2018) (30)
- Study on the mechanism of inhibitory action of 911 on replication of HIV-1 in vitro (2000) (30)
- Divinyl ethers and hydroxy fatty acids from three species ofLaminaria (brown algae) (1993) (30)
- Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. (2012) (30)
- Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L (2021) (29)
- Dictyol H, a new tricyclic diterpenoid from the brown seaweed Dictyota dentata (1985) (29)
- The isolation and characterization of agardhilactone, a novel oxylipin from the marine red alga Agardhiella subulata (1996) (29)
- Role of bacteria in the production and degradation of Microcystis cyanopeptides (2016) (29)
- The stimulatory activities of polysaccharide compounds derived from algae extracts on insulin secretion in vitro. (2008) (28)
- Securing Economic Benefits and Promoting Conservation through Bioprospecting (2006) (28)
- Secondary metabolites from marine cyanobacteria and algae inhibit LFA-1/ICAM-1 mediated cell adhesion. (2004) (28)
- Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows (2015) (28)
- Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. (2015) (28)
- Galactolipids from the temperate red marine alga Gracilariopsis lemaneiformis (1990) (27)
- Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae (2017) (27)
- Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2 (2020) (27)
- ACCORD‐ADEQUATE: an improved technique for the acquisition of inverse‐detected INADEQUATE data (2001) (27)
- Tutuilamides A-C: Vinyl-Chloride Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. (2020) (27)
- Eicosanoids and other hydroxylated fatty acids from the marine alga Gracilariopsis lemaneiformis (1991) (27)
- Optimization of mycelium biomass and exopolysaccharides production by Hirsutella sp . in submerged fermentation and evaluation of exopolysaccharides antibacterial activity (2010) (26)
- Mitsoamide: A cytotoxic linear lipopeptide from the Madagascar marine cyanobacterium Geitlerinema sp. (2007) (26)
- Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate (2016) (26)
- Bioactive and Novel Chemicals from Microalgae (2013) (26)
- Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera. (2011) (26)
- Epoxy allylic carbocations as conceptual intermediates in the biogenesis of diverse marine oxylipins (1996) (26)
- Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts (2013) (26)
- Biosynthesis of the marine cyanobacterial metabolite barbamide. 2: Elucidation of the origin of the thiazole ring by application of a new GHNMBC experiment (1999) (25)
- 5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34 (2017) (25)
- Structure, Synthesis, and Biological Properties of Kalkitoxin (I), a Novel Neurotoxin from the Marine Cyanobacterium Lyngbya majuscula. (2001) (25)
- Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. (2014) (25)
- Discovery of the mammalian insulin release modulator, hepoxilin B3, from the tropical red algae Platysiphonia miniata and Cottoniella filamentosa. (1990) (25)
- Kalkitoxin Inhibits Angiogenesis, Disrupts Cellular Hypoxic Signaling, and Blocks Mitochondrial Electron Transport in Tumor Cells (2015) (25)
- AOS ameliorates monocrotaline-induced pulmonary hypertension by restraining the activation of P-selectin/p38MAPK/NF-κB pathway in rats. (2019) (25)
- Determination of M/G ratio of propylene glycol alginate sodium sulfate by HPLC with pre-column derivatization. (2014) (25)
- The absolute configuration of ecklonialactones A, B, and E, novel oxylipins from brown algae of the genera Ecklonia and Egregia. (1994) (25)
- Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. (2015) (24)
- Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin. (1999) (24)
- Nature's Combinatorial Biosynthesis Produces Vatiamides A-F. (2019) (24)
- Three new malyngamides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. (2003) (24)
- Stereospecific total synthesis of somocystinamide A. (2008) (24)
- Two quinoline alkaloids from the Caribbean cyanobacterium Lyngbya majuscula. (1997) (23)
- Egregiachlorides A-C: New chlorinated oxylipins from the marine brown alga Egregia menziesii (1993) (23)
- The proteasome as a drug target in the metazoan pathogen, Schistosoma mansoni. (2019) (23)
- Laurencione, a heterocycle from the red alga Laurencia spectabilis (1992) (23)
- An expeditious total synthesis of kalkitoxins: determination of the absolute stereostructure of natural kalkitoxin (2004) (23)
- J‐IMPEACH‐MBC: a new concatenated NMR experiment for F1 scalable, J‐resolved HMBC (2001) (23)
- Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group. (2018) (23)
- Characterization of high yield exopolysaccharide produced by Phyllobacterium sp. 921F exhibiting moisture preserving properties. (2017) (23)
- Structural analysis of Kappa-Carrageenan oligosaccharides released by carrageenase from marine cytophaga MCA-2 (2004) (23)
- Weakly antimalarial flavonol arabinofuranosides from Calycolpus warszewiczianus. (2006) (22)
- Bioactive triterpenoids and water-soluble melanin from Inonotus obliquus (Chaga) with immunomodulatory activity (2020) (22)
- Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors. (2014) (22)
- Intra-genomic 16S rRNA gene heterogeneity in cyanobacterial genomes (2011) (22)
- Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins (2009) (22)
- Characterization of the preferred stereochemistry for the neuropharmacologic actions of antillatoxin. (2004) (22)
- Steroids from the soft coral Dendronephthya sp. (2005) (22)
- Screening and evaluation of antiparasitic and in vitro anticancer activities of Panamanian endophytic fungi. (2011) (22)
- Neurotoxic Alkaloids from Cyanobacteria (2007) (22)
- New glycosphingolipids from the marine sponge Halichondria panicea. (1992) (22)
- The heparin-like activities of negatively charged derivatives of low-molecular-weight polymannuronate and polyguluronate. (2017) (21)
- 1-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga (2019) (21)
- Limitations in the use of tubulin polymerization assays as a screen for the identification of new antimitotic agents: The potent marine natural product curacin A as an example (1995) (21)
- Commensal oral Rothia mucilaginosa produces enterobactin – a metal chelating siderophore (2020) (21)
- Production of hydroxy fatty acids by cell suspension cultures of the marine brown alga Laminaria saccharina (1997) (21)
- Coibanoles, a new class of meroterpenoids produced by Pycnoporus sanguineus. (2012) (21)
- Pterocarine, a New Diarylheptanoid from Pterocarya tonkinesis, Its Cell Cycle Inhibition at G0/G1 Phase and Induction of Apoptosis in HCT-15 and K562 Cells (2005) (21)
- Alginate Oligosaccharide Alleviates Monocrotaline-Induced Pulmonary Hypertension via Anti-Oxidant and Anti-Inflammation Pathways in Rats. (2020) (21)
- Three Alginate Lyases from Marine Bacterium Pseudomonas fluorescens HZJ216: Purification and Characterization (2011) (21)
- Heterologous expression of cryptomaldamide in a cyanobacterial host (2020) (21)
- Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov. (2012) (21)
- Molecular Approaches to Discover Marine Natural Product Anticancer Leads – An Update from a Drug Discovery Group Collaboration (2003) (21)
- Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery (2016) (20)
- Coibacins A and B: total synthesis and stereochemical revision. (2014) (20)
- Cymathere ethers A and B : bicyclic oxylipins from the marine brown alga Cymathere triplicata (1992) (20)
- Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. (2017) (20)
- Mooreamide A: A Cannabinomimetic Lipid from the Marine Cyanobacterium Moorea bouillonii (2014) (20)
- Pilot scale culture of the marine cyanobacterium Lyngbya majuscula for its pharmaceutically-useful natural metabolite curacin A (1997) (20)
- Polyenoic fatty acid isomerase from the marine alga Ptilota filicina: protein characterization and functional expression of the cloned cDNA. (2002) (19)
- Characterization of the substrate binding site of polyenoic fatty acid isomerase, a novel enzyme from the marine alga Ptilota filicina. (1997) (19)
- Purification and characterization of polysaccharides degradases produced by Alteromonas sp. A321. (2016) (19)
- Isolation and Structure of Five Lyngbyabellin Derivatives from a Papua New Guinea Collection of the Marine Cyanobacterium Lyngbya majuscula. (2006) (19)
- A β-1,3/1,6-glucan from Durvillaea Antarctica inhibits tumor progression in vivo as an immune stimulator. (2019) (19)
- A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. (2017) (19)
- Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons. (2018) (19)
- Comparative Studies on the Characteristic Fatty Acid Profiles of Four Different Chinese Medicinal Sargassum Seaweeds by GC-MS and Chemometrics (2016) (19)
- Biosynthesis of 13R-hydroxyarachidonic acid, an unusual oxylipin from the red alga lithothamnion corallioides (1993) (19)
- Linoleic acid metabolism in the red algaLithothamnion corallioides: Biosynthesis of 11(R)-hydroxy-9(Z),12(Z)-octadecadienoic acid (1992) (19)
- The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research (2018) (19)
- Discovery of 12-(S)-hydroxy-5,8,10,14-icosatetraenoic acid [12-(S)-HETE] in the tropical red alga Platysiphonia miniata. (1989) (19)
- 12-Lipoxygenase activity in the red marine alga Gracilariopsis lemaneiformis (1990) (18)
- Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways. (2015) (18)
- Isolation of Polycavernoside D from a Marine Cyanobacterium (2015) (18)
- Syntheses of chlorogenin 6α-O-acyl-3-O-β-chacotriosides and their antitumor activities (2005) (18)
- Purification and characterization of a novel enzyme produced by Catenovulum sp. LP and its application in the pre-treatment to Ulva prolifera for bio-ethanol production (2015) (18)
- Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. (2018) (18)
- Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry. (2011) (18)
- Hydroxyalkenylresorcinols from Stylogyne turbacensis. (2007) (18)
- Chemoecological Screening Reveals High Bioactivity in Diverse Culturable Portuguese Marine Cyanobacteria (2013) (18)
- The Metabolome of a Cyanobacterial Bloom Visualized by MS/MS-Based Molecular Networking Reveals New Neurotoxic Smenamide Analogs (C, D, and E) (2018) (18)
- Preparation, characterization and antioxidant activities of polymannuronic acid phosphate, H-phosphonate and sulfate. (2013) (18)
- A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. (2017) (18)
- Synthesis of the marine natural product barbamide. (2001) (18)
- Synthesis of 6'-acylamido-6'-deoxy-α-D-galactoglycerolipids. (2013) (18)
- Bioreactor seaweed cell culture for production of bioactive oxylipins (1995) (17)
- Synthesis of cluster mannosides via a Ugi four-component reaction and their inhibition against the binding of yeast mannan to concanavalin A. (2004) (17)
- Wewakamide A and guineamide G, cyclic depsipeptides from the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula. (2011) (17)
- The Face of a Molecule. (2017) (17)
- 1.08 – Eicosanoids in Nonmammals (1999) (17)
- Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities. (2016) (17)
- Lipopeptides from the Tropical Marine Cyanobacterium Symploca sp. (2014) (16)
- Three new and bioactive icosanoids from the temperate red marine algaFarlowia mollis (1989) (16)
- Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents. (2019) (16)
- Bouillonamide: A Mixed Polyketide–Peptide Cytotoxin from the Marine Cyanobacterium Moorea bouillonii (2013) (16)
- Purification and characterization of chondroitinase ABC from Acinetobacter sp. C26. (2017) (16)
- Vidalenolone, a novel phenolic metabolite from the tropical red alga Vidalia sp. (2002) (16)
- Modulation of Lipid Metabolism by Deep-Sea Water in Cultured Human Liver (HepG2) Cells (2014) (16)
- Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore (2019) (16)
- Bioprospection of Microalgae and Cyanobacteria as Biocontrol Agents Against Vibrio campbellii and Their Use in White Shrimp Litopenaeus vannamei Culture (2012) (16)
- Synthesis of bidesmosidic dihydrodiosgenin saponins bearing a 3-O-beta-chacotriosyl moiety. (2004) (16)
- Dilophic acid, a diterpenoid from the tropical brown seaweed Dilophus guineensis (1987) (16)
- Purification and Characterization of Hyaluronate Lyase from Arthrobacter globiformis A152 (2017) (16)
- Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation. (2011) (15)
- Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking. (2020) (15)
- Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking. (2020) (15)
- Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions. (2021) (15)
- Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta. (2018) (15)
- Sarcoglycosides A - C, New O-Glycosylglycerol Derivatives from the South China Sea Soft Coral Sarcophyton infundibuliforme (2009) (15)
- Isolation of a cyclic carbonate, a gamma-butyrolactone, and a new indole derivative from the marine cyanobacterium Lyngbya majuscula. (1995) (15)
- MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria (2018) (15)
- A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria (2021) (14)
- Streptomyces artemisiae MCCB 248 isolated from Arctic fjord sediments has unique PKS and NRPS biosynthetic genes and produces potential new anticancer natural products (2017) (14)
- Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata (2017) (14)
- Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens. (2013) (14)
- Heparinase 1 selectivity for the 3 , 6-diO-sulfo-2-deoxy-2-sulfamido-α-D-glucopyranose ( 1 , 4 ) 2O-sulfo-α-L-idopyranosyluronic acid ( GlcNS 3 S 6 S-IdoA 2 S ) linkages (2010) (14)
- Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease (2018) (14)
- Development of an enteric nanoparticle of marine sulfated polysaccharide propylene glycol alginate sodium sulfate for oral administration: formulation design, pharmacokinetics and efficacy (2018) (14)
- Structural studies on kappa-carrageenan derived oligosaccharides. (2002) (14)
- Synthesis of the Cytotoxic Gitogenin 3β-O-[2-O-(α-l-Rhamnopyranosyl)-β-d-galactopyranoside] and its Congeners (2006) (13)
- PRODUCTION OF BIOACTIVE METABOLITES BY CELL AND TISSUE CULTURES OF MARINE MACROALGAE IN BIOREACTOR SYSTEMS (1999) (13)
- Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity (2020) (13)
- The Chemistry of Marine Algae and Cyanobacteria (2012) (13)
- 20S Proteasome as a Drug Target in Trichomonas vaginalis (2019) (13)
- Absolute stereochemistry of neohalicholactone from the brown alga Laminaria sinclairii. (1994) (13)
- Eicosanoids from the Rhodophyta: new metabolism in the algae (1990) (13)
- [6-13C]-(2S, 4S)-5-chloroleucine: synthesis and incubation studies with cultures of the cyanobacterium, Lyngbya majuscula (2003) (13)
- Zelnorm, an agonist of 5-Hydroxytryptamine 4-receptor, acts as a potential antitumor drug by targeting JAK/STAT3 signaling (2019) (13)
- Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. (2018) (13)
- Involvement of JNK and Caspase Activation in Hoiamide A-Induced Neurotoxicity in Neocortical Neurons (2015) (13)
- Synthesis of glycoglycerolipid of 1,2-dipalmitoyl-3-(N-palmitoyl-6'-amino-6'-deoxy-α-D-glucosyl)-sn-glycerol and its analogues, inhibitors of human Myt1-kinase. (2012) (12)
- A novel uncultured heterotrophic bacterial associate of the cyanobacterium Moorea producens JHB (2016) (12)
- Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans' aldol reaction with a tertiary enolate. (2011) (12)
- Biologically active new metabolites from a Florida collection of Moorea producens (2017) (12)
- Novel pyrroles from the Oregon red alga Gracilariopsis lemaneiformis. (1991) (12)
- Cymatherelactone and cymatherols A-C, polycyclic oxylipins from the marine brown alga Cymathere triplicata. (2012) (12)
- Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent. (2017) (12)
- Use of 1H-15N PEP-HSQC-TOCSY at natural abundance to facilitate the structure elucidation of naturally occurring peptides (1999) (11)
- Studies of marine sulfated polymannuroguluronate on endothelial cell proliferation and endothelial immunity and related mechanisms. (2003) (11)
- An aldehyde-containing galactolipid from the red algaGracilariopsis lemaneiformis (1991) (11)
- A Convolutional Neural Network-based approach for the Rapid Annotation of Molecularly Diverse Natural Products (2020) (11)
- Polyhydroxy cyclohexanols from a Dendrodochium sp. fungus associated with the sea cucumber Holothuria nobilis Selenka. (2014) (11)
- Open Access Repository-Scale Propagated Nearest Neighbor Suspect Spectral Library for Untargeted Metabolomics (2022) (11)
- Alginate oligosaccharide alleviates D‐galactose‐induced cardiac ageing via regulating myocardial mitochondria function and integrity in mice (2021) (11)
- Somocystinamide A, a Novel Cytoxic Disulfide Dimer from a Fijian Marine Cyanobacterial Mixed Assemblage. (2002) (11)
- Structure and molecular morphology of a novel moisturizing exopolysaccharide produced by Phyllobacterium sp. 921F. (2019) (11)
- The Secondary Metabolites and Biosynthetic Gene Clusters of Marine Cyanobacteria . Applications in Biotechnology (2005) (11)
- Structure-activity relationship of propylene glycol alginate sodium sulfate derivatives for blockade of selectins binding to tumor cells. (2019) (11)
- Ichthyotoxic brominated diphenyl ethers from a mixed assemblage of a red alga and cyanobacterium: structure clarification and biological properties. (2010) (11)
- Effects of low-molecular-weight polyguluronate sulfate on experimental urolithiasis in rats (2007) (10)
- Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis. (2019) (10)
- Simultaneous determination of gypenoside LVI, gypenoside XLVI, 2α-OH-protopanaxadiol and their two metabolites in rat plasma by LC-MS/MS and its application to pharmacokinetic studies. (2015) (10)
- Detailed Analysis of (−)-Palmyrolide A and Some Synthetic Derivatives as Voltage-Gated Sodium Channel Antagonists (2014) (10)
- Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp. (2019) (10)
- Native metabolomics identifies the rivulariapeptolide family of protease inhibitors (2021) (10)
- Chemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass (2014) (10)
- Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from Streptomyces sp. (2015) (10)
- Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens. (2019) (10)
- Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore (2020) (10)
- ADDITIONAL ANTI-LEISHMANIAL CONSTITUENTS OF THE PANAMANIAN ENDOPHYTIC FUNGUS Edenia sp. (2009) (10)
- The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods. (2011) (10)
- Cytotoxic halogenated monoterpenes from Plocamium cartilagineum (2017) (10)
- Gloiosiphones A and B, novel metabolites from the red marine alga Gloiosiphonia verticillaris (1993) (10)
- Propylene glycol guluronate sulfate (PGGS) reduces lipid accumulation via AMP-activated kinase activation in palmitate-induced HepG2 cells. (2018) (10)
- Cell-free biosynthesis and source of hydroxyl groups in (12R,13S)-dihydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid, a novel eicosanoid from the marine alga Gracilariopsis lemaneiformis. (1991) (9)
- Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites (2013) (9)
- Drugs from the Sea (1987) (9)
- 2-chloro-1,6(S*),8-tribromo-3-(8)(Z)-ochtodene: a metabolite of the tropical red seaweed ochtodes secundiramea (1984) (9)
- Structural Diversity of Marine Oxylipins (2002) (9)
- Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems. (2000) (8)
- Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities (2017) (8)
- Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A. (2020) (8)
- Acetylcholinesterase inhibitors and antioxidants mining from marine fungi: bioassays, bioactivity coupled LC–MS/MS analyses and molecular networking (2020) (8)
- Dragocins A-D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium. (2019) (8)
- Preparation, characterization and pharmacokinetics of fluorescence labeled propylene glycol alginate sodium sulfate (2014) (8)
- Dicitrinones E and F, citrinin dimers from the marine derived fungus Penicillium citrinum HDN-152-088 (2019) (8)
- Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria. (2018) (8)
- Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea (2014) (8)
- The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria (2020) (8)
- Efficient gusA transient expression in Porphyra yezoensis protoplasts mediated by endogenous beta-tubulin flanking sequences (2007) (8)
- Structural Basis of Polyketide Synthase O-Methylation. (2018) (8)
- Effects and mechanisms of PSS-loaded nanoparticles on coronary microcirculation dysfunction in streptozotocin-induced diabetic cardiomyopathy rats. (2019) (8)
- Development and validation of a high-performance liquid chromatographic method for the determination of stemoninine in rat plasma after administration of Stemona tuberosa extracts. (2011) (8)
- The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria (2020) (8)
- Synthesis and antiviral evaluation of 6'-acylamido-6'-deoxy-α-D-mannoglycerolipids. (2013) (8)
- Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke (2020) (8)
- Absolute Configuration of Curacin A, a Novel Antimitotic Agent from the Tropical Marine Cyanobacterium Lyngbya majuscula. (1995) (8)
- Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién (2019) (7)
- Two new chamigrene sesquiterpenoids from the tropical red alga laurencia obtusa (1987) (7)
- Total Synthesis of Myrmekioside A, a Mono-O-alkyl-diglycosylglycerol from Marine Sponge Myrmekioderma sp. (2015) (7)
- Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species. (2017) (7)
- An unprecedented N-transacylation reaction on 2-acetamido-2-deoxy-α-d-glucopyranosides (2004) (7)
- Rapid isolation and sequence analysis of the beta-tubulin gene from Porphyra yezoensis (Rhodophyta) (2005) (7)
- Bioactive new metabolites from the green alga Udotea orientalis growing on the Gorgonian coral Pseudopterogorgia rigida (2017) (7)
- Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid (1996) (7)
- Plant Sources of Drugs and Chemicals (2013) (7)
- The Inhibitory Effect of Propylene Glycol Alginate Sodium Sulfate on Fibroblast Growth Factor 2-Mediated Angiogenesis and Invasion in Murine Melanoma B16-F10 Cells In Vitro (2019) (7)
- Aplysia sea hare assimilation of secondary metabolites from brown seaweed,Stypopodium zonale (1989) (7)
- Bio-Assay Guided Isolation of Germacranes with Anti-Protozoan Activity from Magnolia sororum (2007) (7)
- Synthesis and Pharmacological Evaluation of Novel Conjugates of Indomethacin with Antioxidant Activity (2005) (7)
- Interaction of the cyanobacterial thiazoline‐containing lipid curacin A with bovine brain tubulin (1997) (7)
- Self-assembling nanoparticles of dually hydrophobic prodrugs constructed from camptothecin analogue for cancer therapy. (2020) (7)
- Semi-synthesis of Several Stigmasterol Saponins (2006) (7)
- Spatial and seasonal variations in bacterial communities of the Yellow Sea by T-RFLP analysis (2009) (7)
- Discovery of novel cannabinoid receptor ligands from diverse marine organisms. (1997) (7)
- Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea (2016) (7)
- Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids. (2016) (7)
- What depth should deep-sea water be pumped up from in the South China Sea for medicinal research? (2013) (6)
- Synthesis of furostanol glycosides: discovery of a potent α-glucosidase inhibitor. (2016) (6)
- Small Molecule DFPM Derivative-Activated Plant Resistance Protein Signaling in Roots Is Unaffected by EDS1 Subcellular Targeting Signal and Chemical Genetic Isolation of victr R-Protein Mutants (2016) (6)
- An anti-inflammatory isoflavone from soybean inoculated with a marine fungus Aspergillus terreus C23-3 (2020) (6)
- Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L (2020) (6)
- Sulfated polymannuroguluronate TGC161 ameliorates leukopenia by inhibiting CD4+ T cell apoptosis (2020) (6)
- Secondary Metabolite Variation and Bioactivities of Two Marine Aspergillus Strains in Static Co-Culture Investigated by Molecular Network Analysis and Multiple Database Mining Based on LC-PDA-MS/MS (2022) (6)
- Synthesis of Two Natural Oleanolic Acid Saponins (2006) (6)
- The antioxidant effects of complexes of tilapia fish skin collagen and different marine oligosaccharides (2010) (6)
- Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi. (2022) (6)
- Bioassay-guided extraction of crude fucose-containing sulphated polysaccharides from Sargassum fusiforme with response surface methodology (2016) (5)
- Synthesis and Anti-Influenza A Virus Activity of 6′-amino-6′-deoxy-glucoglycerolipids Analogs (2016) (5)
- Total Structure of Hormothamnin A, a Toxic Cyclic Undecapeptide from the Tropical Marine Cyanobacterium Hormothamnion enteromorphoides. (1992) (5)
- Convergent Synthesis of Solamargine and Analogues Thereof: Structural Revision of 16‐epi‐Solamargine and Cytotoxic Evaluation (2015) (5)
- SMART-Miner: A Convolutional Neural Network-based Metabolite Identification from 1 H-13 C HSQC spectra. (2021) (5)
- LINKING INSIGHTS FROM ECOLOGICAL RESEARCH WITH BIOPROSPECTING TO PROMOTE CONSERVATION , ENHANCE RESEARCH CAPACITY , AND PROVIDE ECONOMIC USES OF BIODIVERSITY (2008) (5)
- Metal-N-saccharide chemistry: synthesis and structure determination of two Cu(II) complexes containing glycosylamines. (2004) (5)
- Dual-target inhibitor screening against thrombin and factor Xa simultaneously by mass spectrometry. (2017) (5)
- A Universal Language for Finding Mass Spectrometry Data Patterns (2022) (5)
- A novel strategy to screen inhibitors of multiple aminoglycoside‐modifying enzymes with ultra‐high performance liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry (2019) (5)
- Taveuniamides: New Chlorinated Toxins from a Mixed Assemblage of Marine Cyanobacteria. (2004) (5)
- Pyrazinopyrimidine alkaloids from a mangrove-derived fungus Aspergillus versicolor HDN11-84. (2021) (5)
- Metal-ion-binding properties of ulvan extracted from Ulva clathrata and structural characterization of its complexes. (2021) (5)
- Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B. (2022) (4)
- Total Synthesis of Sulfated Glycosphingolipid SM1a, a Kind of Human Epithelial Carcinoma Antigen (2015) (4)
- The Anticancer Mechanism of an Approved Disease Modifying Herb Medicine:Total Glucosides of Paeony Target both EGFR and HER-2 in Lung Cancer Cell Lines (2014) (4)
- MetaRiPPquest: A Peptidogenomics Approach for the Discovery of Ribosomally Synthesized and Post-translationally Modified Peptides (2017) (4)
- Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance (2022) (4)
- 12α,13‐Dihydroxyolean‐3‐oxo‐28‐oic Acid, a New Triterpene, and the Known Oleanonic Acid as a New Cell Cycle Inhibitors from Schefflera venulosa. (2005) (4)
- Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii (2020) (4)
- Chapter 4 - Nitrogen-Containing Metabolites from Marine Bacteria (1999) (4)
- NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters (2022) (3)
- Separation of Rabbit Liver Metallothionein Sub-isoforms by RP-HPLC with MALDI-TOF-MS Detection (2002) (3)
- (1,4) 2-O-sulfo- α-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages (2010) (3)
- Temperature Plays an Essential Regulatory Role in the Tumor Immune Microenvironment. (2021) (3)
- Defining the Yeast Resistome through in vitro Evolution and Whole Genome Sequencing (2021) (3)
- On the Hunt for New Toxin Families Produced by a Mediterranean Strain of the Benthic Dinoflagellate Ostreopsis cf. ovata (2022) (3)
- Structure of Curacin A (I), a Novel Antimitotic, Antiproliferative, and Brine Shrimp Toxic Natural Product from the Marine Cyanobacterium Lyngbya majuscula. (1994) (3)
- Kalkitoxin Reduces Osteoclast Formation and Resorption and Protects against Inflammatory Bone Loss (2021) (3)
- Biosynthesis and cannabinoid receptor affinity of the novel eicosanoid, conjugated triene anandamide. (1997) (3)
- Synergistic allelochemicals from a freshwater (2010) (3)
- [Advances in algae tool enzymes: alginate lyases]. (2011) (3)
- Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β‐Amino Acids. (2016) (2)
- Total Synthesis of Laucysteinamide A, a Monomeric Congener of Somocystinamide A. (2021) (2)
- Antillatoxin-Stimulated Neurite Outgrowth Involves the Brain-Derived Neurotrophic Factor (BDNF) - Tropomyosin Related Kinase B (TrkB) Signaling Pathway. (2022) (2)
- Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides (2022) (2)
- First Total Synthesis and Structure-Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium. (2021) (2)
- 2.06 The Natural Products Chemistry of Cyanobacteria (2010) (2)
- Sarcoglycosides A-C, New O-Glycosylglycerol Derivatives from the South China Sea Soft Coral Sarcophyton infundibuliforme (2010) (2)
- Antileishmanial constituents of the panamanian endophytic fungus Phoma herbarum strain M16 (2008) (2)
- Development of a UHPLC-MS method for inhibitor screening against α-L-1,3-fucosidase (2019) (2)
- Preclinical development of Aneustat (OMN54): a multifunctional multi-targeted natural product derivative with anti-tumor, anti-inflammatory and immuno-modulatory activity (2007) (2)
- Elegant metabolite biosynthesis. (2011) (2)
- Special issue in honor of William Fenical, a pioneer in marine natural products discovery and drug development. (2015) (2)
- Novel Marine Compounds Modulate Mitochondrial Function in H9c2 Cells: Potential New Pharmaceutical Targets to Control Cardiac Metabolism (2018) (2)
- The Unique Mechanistic Transformations Involved in the Biosynthesis of Modular Natural Products from Marine Cyanobacteria (2010) (2)
- Heterologous Expression in Anabaena of the Columbamide Pathway from the Cyanobacterium Moorena bouillonii and Production of New Analogs. (2022) (2)
- High Titer Heterologous Production of Lyngbyatoxin in E. coli , a Protein Kinase C Activator from an Uncultured Marine Cyanobacterium (2014) (2)
- Using Deep Siamese Neural Networks to Speed up Natural Products Research (2018) (2)
- 5. Marine Bioprospecting (2014) (2)
- Synthesis of Indomethacin Conjugates with D-Glucosamine (2005) (2)
- Phytochemical analysis and antileishmanial activity of Desmotes incomparabilis, an endemic plant from Panama (2008) (1)
- Development of Potent and Highly Selective Epoxyketone-based Plasmodium Proteasome Inhibitors. (2023) (1)
- Giant Marine Cyanobacteria Produce Exciting Potential Pharmaceuticals Cyanobacteria produce an array of exceptionally potent toxins, some with promising anticancer or other anti-disease activities (2008) (1)
- Natural products: Are we close to the end? (2015) (1)
- A supervised fingerprint-based strategy to connect natural product mass spectrometry fragmentation data to their biosynthetic gene clusters (2021) (1)
- Production of Bioactive Compounds by Cell and Tissue Cultures of Marine Seaweeds in Bioreactor System (1998) (1)
- Luquilloamides, Cytotoxic Lipopeptides from a Puerto Rican Collection of the Filamentous Marine Cyanobacterium Oscillatoria sp. (2021) (1)
- Antimutagenic, Antiinflammatory, and Potential Anticancer Substances from Marine Algae (1997) (1)
- Erratum to “Biosynthetic pathway and origin of the chlorinated methyl group in barbamide and dechlorobarbamide, metabolites from the marine cyanobacterium Lyngbya majuscula”: [Tetrahedron 56 (2000) 9103–9113] (2001) (1)
- Corrigendum to: "Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons" [Phytochemistry (2018) 150 85-92]. (2018) (1)
- Involvement of Phosphoinositide 3‐kinase‐Akt signaling pathway in sodium channel activator‐induced neurite outgrowth (2010) (1)
- SCREENING FOR ANTICANCER LEADS FROM MARINE ORGANISMS IN A MECHANISM-BASED DRUG DISCOVERY PROGRAM (1994) (1)
- Improved Scalable Synthesis of Clinical Candidate KZR‐616, a Selective Immunoproteasome Inhibitor (2021) (1)
- Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions (2022) (1)
- Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high (2017) (1)
- Chemical Biology of Marine Cyanobacteria (2017) (1)
- Genomic insights into secondary metabolism of the natural product-rich cyanobacterium Moorea bouillonii (2012) (1)
- Monomeric and Dimeric Bromophenols from the Red Alga Ceramium Sp. with Antioxidant and Anti-Inflammatory Activities (2020) (1)
- Approach for construction of a completely synthetic human antibody library from well--expressed framework (2004) (1)
- New polyketides from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata (2009) (1)
- Low molecular-weight polyguluronate phosphate: An immunostimulant by activating splenocyte/macrophage in vitro and improving immune response in vivo. (2022) (1)
- Erratum to: Sequence analysis of alginate-derived oligosaccharides by negative-ion electrospray tandem mass spectrometry (2006) (1)
- Purification and characterization of chondroitinase ABC from Acinetobacter sp . C 26 (2016) (1)
- Synthesis and pharmacokinetic property improvement of deuterated plinabulin 9 (2017) (1)
- Prophylactic effects of chitin derivative “916” on atherogenesis in hypercholesterolemic rabbits (2000) (1)
- Microbial Screening of Marine Natural Product Inhibitors for the 6′-Aminoglycoside Acetyltransferase 2″-Aminoglycoside Phosphotransferase [AAC(6′)-APH(2″)] Bifunctional Enzyme by Ultra-High Performance Liquid Chromatography–Mass Spectrometry (UHPLC-MS) (2021) (1)
- Identification of Barley Varieties Used in Beer Production by Microsatellite DNA Markers (2007) (1)
- Inhibitory effects of D-polymannuronic sulfate on the proliferation of rat smooth muscle cells (2000) (1)
- Spectroscopic networking based dereplication applied to a strain of Moorea producens affords a fuller picture of its metabolome (2012) (1)
- Pterocaryquinone, a Novel Naphthoquinone Derivative from Pterocarya tonkinesis. (2007) (0)
- Hydroxylated polymethoxyflavones induce p53 and Bax dependent apoptosis and cell cycle arrest. (2010) (0)
- The unusual mechanism of action of the microtubule targeted drug curacin A (2004) (0)
- Mass spectrometry tools for screening of marine cyanobacterial natural products (2015) (0)
- Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance (2022) (0)
- Kinetics and molecular dynamic modeling of a potent and selective marine natural product inhibitor of human cathepsin L (975.3) (2014) (0)
- Discovery of novel chlorinated acyl amides from a marine cyanobacterium using integrated technologies (2015) (0)
- Honaucins A–C, Potent Inhibitors of Eukaryotic Inflammation and Bacterial Quorum Sensing: Synthetic Derivatives and Structure-Activity Relationships (2013) (0)
- The inhibitory effect of 5‐hydroxy‐hexamethoxyflavone on human colon cancer cells (2011) (0)
- Coibacins A and B: Total Synthesis, Stereochemical Revision and Structural Elucidation (2013) (0)
- Faculty Opinions recommendation of The cryoem method microed as a powerful tool for small molecule structure determination. (2018) (0)
- New Diffusion‐Edited NMR Experiments to Expedite the Dereplication of Known Compounds from Natural Product Mixtures. (2000) (0)
- Faculty Opinions recommendation of Corporate control and global governance of marine genetic resources. (2018) (0)
- Author Correction: Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research (2020) (0)
- Redacted for Privacy Redacted for Privacy (2012) (0)
- Isolation and structure elucidation of five new cytotoxic chlorinated lipopetides from Moorea bouillonii (2012) (0)
- Three New Malyngamides from the Marine Cyanobacterium Lyngbya majuscula. (1998) (0)
- UNIVERSITY OF CALIFORNIA, SAN DIEGO Mass Spectrometry guided Analogs of Bioactive Molecule Discovery A Thesis submitted in partial satisfaction of the requirements for the degree Master of Science in Chemistry (2014) (0)
- Structure Activity Relationships of the Bioactive Lyngbyamide Class of Marine Natural Product (2013) (0)
- Supplemental Information Apratoxin Kills Cells by Direct Blockade of the Sec 61 Protein Translocation Channel (2016) (0)
- Faculty Opinions recommendation of Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy. (0)
- Integrating disciplines in the natural products sciences: The story of Curacin A (2012) (0)
- Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research (2017) (0)
- I SOLATION AND S TRUCTURE E LUCIDATION OF B IOACTIVE C YCLIC P EPTIDES FROM M ARINE (2011) (0)
- Faculty Opinions recommendation of An integrated approach for mixture analysis using MS and NMR techniques. (2019) (0)
- CCDC 983568: Experimental Crystal Structure Determination (2016) (0)
- SIRT1 Activation Enhancing 8,3′-Neolignans from the Twigs of Corylopsis coreana Uyeki (2021) (0)
- Kalkitoxin: A Potent Suppressor of Distant Breast Cancer Metastasis (2023) (0)
- 1-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga (2019) (0)
- The influence of dihydropyridines calcium antagonists on 5-HT-induced intracellular calcium signal (2007) (0)
- New Books (2009) (0)
- The Isolation and Characterization of Agardhilactone, a Novel Oxylipin from the Marine Red Alga Agardhiella subulata. (1996) (0)
- Harnessing the Pharmaceutical Potential of Marine Cyanobacteria (2011) (0)
- ILVII-2 ULTRA-POTENT LINEAR LIPOPEPTIDE NATURAL PRODUCTS FROM DIVERSE MARINE CYANOBACTERIA(Chemistry and Biochemistry Related to Biodiversity) (2006) (0)
- This Highlight article describes three different imaging mass spectrometry (IMS) approaches, MALDI, DESI and SIMS and their recent applications in the analysis of natural products. IMS has opened up a new avenue for establishing the functional roles of natural products. (2009) (0)
- Development of in vitro and in vivo anti‐inflammatory assays for testing cyanobacterial marine natural products (2008) (0)
- Cyanobacteria-shrimp colonies in the Mariana Islands (2021) (0)
- Hoiamide D (I), a Marine Cyanobacteria‐Derived Inhibitor of p53/MDM2 Interaction. (2012) (0)
- Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium. (2021) (0)
- Isolation and identification of an anticancer activity triterpenoid from Pterocarya tonkinesis (Franch.) Dode. (2002) (0)
- Alotamide A (I), a Novel Neuropharmacological Agent from the Marine Cyanobacterium Lyngbya bouillonii (2010) (0)
- Faculty Opinions recommendation of Quercetin-loaded microcapsules ameliorate experimental colitis in mice by anti-inflammatory and antioxidant mechanisms. (2013) (0)
- Faculty Opinions recommendation of A marine viral halogenase that iodinates diverse substrates. (2019) (0)
- Special Issue in Honor of D. John Faulkner and Paul J. Scheuer (2004) (0)
- Hydrolysis of heparinase I to synthetic heparin-pentasaccharide and effect on its anti-factor Xa activity (2001) (0)
- Rapid Biotic and Abiotic Transformation of Toxins produced by Ostreopsis. cf. ovata (2022) (0)
- An Expeditious Total Synthesis of Kalkitoxins: Determination of the Absolute Stereostructure of Natural Kalkitoxin. (2004) (0)
- Modulation of Lipid Metabolism by Deep-Sea Water in Cultured Human Liver (HepG2) Cells (2013) (0)
- Faculty Opinions recommendation of 15-Hydroperoxy-PGE2 : Intermediate in Mammalian and Algal Prostaglandin Biosynthesis. (2020) (0)
- Intramolecular interactions enhance the potency of gallinamide A analogs against Trypanosoma cruzi (2021) (0)
- Development of Highly Selective Epoxyketone-based Plasmodium Proteasome Inhibitors with Negligible Cytotoxicity (2022) (0)
- A novel uncultured heterotrophic bacterial associate of the cyanobacterium Moorea producens JHB (2016) (0)
- Development of subunit selective substrates for Trichomonas vaginalis proteasome (2023) (0)
- Honaucin A, mechanism of action and role as a potential cancer prevention agent (2015) (0)
- Corrigendum: Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria. (2016) (0)
- Enantioselective Synthesis of Malhamensilipin A (2010) (0)
- Faculty Opinions recommendation of Modular approaches to lankacidin antibiotics. (2020) (0)
- ChemInform Abstract: Survey of NMR Experiments for the Determination of NJ(C,H) Heteronuclear Coupling Constants in Small Molecules. (2002) (0)
- Vanguards of Natural Product Research 2021 (2021) (0)
- An Unprecedented N-Transacylation Reaction of 2-Acetamido-2-deoxy-α-D-glucopyranosides. (2004) (0)
- Secondary metabolites from Panamanian mat forming cyanobacteria (2012) (0)
- Harnessing the Pharmaceutical Potential of Marine Cyanobacteria - eScholarship (2011) (0)
- Correction to "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp." (2020) (0)
- TOXIC METABOLITES OF BLUE-GREEN ALGAE; MENACE OR MEDICINE?: ISEE-605 (2003) (0)
- The Biology-Chemistry Interface, A Tribute to Koji Nakanishi Edited by R. Cooper (Pharmanex, Inc.) and J. K. Snyder (Boston University). Marcel Dekker, Inc., New York, NY. 1999. xv + 491 pp. 15 × 22.5 cm. $195.00. ISBN 0 8247-7116-8. (2000) (0)
- Belamide A, a New Antimitotic Tetrapeptide from a Panamanian Marine Cyanobacterium. (2006) (0)
- Syntheses of chlorogenin 6alpha-O-acyl-3-O-beta-chacotriosides and their antitumor activities. (2005) (0)
- In vitro Biosynthesis of Hydroxyicosanoids by the Temperate Marine Alga Gracilariopsis lemaneiformis (1990) (0)
- Promoting research on the uses of biodiversity and correcting misconceptions (2006) (0)
- Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. (2023) (0)
- Author Correction: Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research (2020) (0)
- Discovery of Novel Tyrosinase Inhibitors From Marine Cyanobacteria (2022) (0)
- Biphasic modulation of human cathepsin L by a novel cyanobacterial depsipeptide (2015) (0)
- Discovery and development of Santacruzamate A, a potent and selective histone deacetylase inhibitor (2012) (0)
- Malyngamide I from the Tropical Marine Cyanobacterium Lyngbya majuscula and the Probable Structure Revision of Stylocheilamide. (2010) (0)
- Book Review:Eicosanoids and Related Compounds in Plants and Animals A. F. Rowley, H. Kuhn, T. Schewe (2000) (0)
- Natural products that selectively target organotropic metastatic breast cancer (2014) (0)
- HeparinMappingUsingHeparin Lyases and theGeneration of aNovel LowMolecularWeightHeparin (2011) (0)
- HPLC Method for Microanalysis and Pharmacokinetics of Marine Sulfated Polysaccharide, Propylene Glycol Alginate Sodium Sulfate (2014) (0)
- Direct Determination of Enzymes in Dried Blood Spots by High-Performance Liquid Chromatography – Mass Spectrometry (HPLC-MS) for the Screening of Antithrombotic Agents (2022) (0)
- Marine Sulfated Polysaccharide PMGS Synergizes with Paclitaxel in Inhibiting Cervical Cancer In Vitro (2023) (0)
- Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites (2012) (0)
- Drug Discovery from Marine Microbes (2012) (0)
- Corrigendum to “Cymatherelactone and cymatherols A–C, polycyclic oxylipins from the marine brown alga Cymathere triplicata” [Phytochemistry 73 (2012) 134–141] (2012) (0)
- Bioavailability of anti‐carcinogenic hydroxylated polymethoxyflavones in mice (2011) (0)
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What Schools Are Affiliated With William H. Gerwick?
William H. Gerwick is affiliated with the following schools:
- Ningbo University
- University of Papua New Guinea
- California State University, Chico
- University of Freiburg
- Oregon State University
- Ocean University of China
- Rhodes University
- Autonomous University of Baja California
- Nagoya City University
- Heinrich Heine University Düsseldorf
- University of Michigan
- University of California, San Diego
- University of South Florida
