William J. Mcginnis
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Biology
Why Is William J. Mcginnis Influential?
(Suggest an Edit or Addition)William J. Mcginnis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Homeobox genes and axial patterning (1992) (2646)
- The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans (2008) (1032)
- A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes (1984) (971)
- Modulating Hox gene functions during animal body patterning (2005) (842)
- A homologous protein-coding sequence in drosophila homeotic genes and its conservation in other metazoans (1984) (826)
- Hox protein mutation and macroevolution of the insect body plan (2002) (376)
- Multiplex Detection of RNA Expression in Drosophila Embryos (2004) (372)
- Genomic Evolution of Hox Gene Clusters (2006) (368)
- Shaping animal body plans in development and evolution by modulation of Hox expression patterns (1998) (321)
- Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins (1984) (308)
- Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts (1985) (300)
- Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes (1984) (289)
- Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of drosophila (1984) (269)
- Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster. (1985) (269)
- Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo. (1989) (251)
- Spatially regulated expression of homeotic genes in Drosophila. (1985) (221)
- An Epidermal Barrier Wound Repair Pathway in Drosophila Is Mediated by grainy head (2005) (218)
- Autoregulation of a drosophila homeotic selector gene (1988) (212)
- The Drosophila Hox Gene Deformed Sculpts Head Morphology via Direct Regulation of the Apoptosis Activator reaper (2002) (210)
- Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in Drosophila embryos and larvae (1990) (209)
- A transposable element inserted just 5′ to a Drosophila glue protein gene alters gene expression and chromatin structure (1983) (189)
- Homeo box genes of the Antennapedia and Bithorax Complexes of Drosophila (1985) (178)
- Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae (1990) (177)
- Developmental and molecular analysis of Deformed; a homeotic gene controlling Drosophila head development (1987) (176)
- Spatial restriction in expression of a mouse homoeo box locus within the central nervous system (1986) (170)
- DEAF‐1, a novel protein that binds an essential region in a Deformed response element. (1996) (153)
- A model for extradenticle function as a switch that changes HOX proteins from repressors to activators (1997) (153)
- Developmental patterning genes and their conserved functions: from model organisms to humans. (2000) (148)
- Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity. (1997) (127)
- Homeo box gene complex on mouse chromosome 11: Molecular cloning, expression in embryogenesis, and homology to a human homeo box locus (1985) (120)
- Mapping functional specificity in the Dfd and Ubx homeo domains. (1992) (120)
- Visualization of Individual Scr mRNAs during Drosophila Embryogenesis Yields Evidence for Transcriptional Bursting (2009) (118)
- A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos (1989) (118)
- Different transcripts of the Drosophila Abd‐B gene correlate with distinct genetic sub‐functions. (1988) (103)
- A human HOX4B regulatory element provides head-specific expression in Drosophila embryos (1992) (102)
- Evolution of transcription factor function. (2003) (95)
- Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation (1999) (90)
- Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster. (1999) (90)
- An autoregulatory enhancer element of the Drosophila homeotic gene Deformed. (1990) (88)
- Region-specific expression of two mouse homeo box genes (1987) (87)
- Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax (2005) (84)
- Antp‐type homeodomains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos. (1992) (84)
- spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk. (1999) (82)
- High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene. (1991) (82)
- Temporal and spatial distribution of transcripts from the Deformed gene of Drosophila (1987) (81)
- Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes (1985) (78)
- Prader-Willi and Angelman syndromes: diagnosis with a bisulfite-treated methylation-specific PCR method. (1997) (77)
- Distal-less is a downstream gene of Deformed required for ventral maxillary identity. (1993) (75)
- A cap 'n' collar protein isoform contains a selective Hox repressor function. (1998) (71)
- Deformed protein binding sites and cofactor binding sites are required for the function of a small segment‐specific regulatory element in Drosophila embryos. (1994) (71)
- The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function. (1993) (71)
- A novel, tissue‐specific, Drosophila homeobox gene. (1988) (70)
- Pair-rule segmentation genes regulate the expression of the homeotic selector gene, Deformed (1988) (70)
- Rules of the road for insect gene drive research and testing (2017) (69)
- A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development. (1997) (68)
- Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head. (2000) (67)
- Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila (2011) (65)
- Multiple transcription factor codes activate epidermal wound–response genes in Drosophila (2009) (60)
- Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution. (1999) (60)
- Hox genes differentially regulate Serrate to generate segment-specific structures. (1999) (58)
- The molecular architects of body design. (1994) (56)
- The Functions of Grainy Head-Like Proteins in Animals and Fungi and the Evolution of Apical Extracellular Barriers (2012) (53)
- Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier (2010) (52)
- DNA sequence changes in an upstream DNase I-hypersensitive region are correlated with reduced gene expression. (1983) (52)
- DEAF‐1 function is essential for the early embryonic development of drosophila (2002) (52)
- Co-option of an anteroposterior head axis patterning system for proximodistal patterning of appendages in early bilaterian evolution. (2010) (45)
- A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function. (1998) (45)
- A new Drosophila homeobox gene, bsh, is expressed in a subset of brain cells during embryogenesis. (1993) (44)
- Establishment of the Deformed expression stripe requires the combinatorial action of coordinate, gap and pair‐rule proteins. (1990) (40)
- Altering the regulatory targets of the Deformed protein in Drosophila embryos by substituting the Abdominal-B homeodomain (1990) (39)
- A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element. (1999) (36)
- From DNA to Diversity, Molecular Genetics and the Evolution of Animal Design, 2nd edition (2005) (36)
- Serine Proteolytic Pathway Activation Reveals an Expanded Ensemble of Wound Response Genes in Drosophila (2013) (35)
- Ectopic expression from the Deformed gene triggers a dominant defect in Drosophila adult head development. (1990) (33)
- Regulation by homeoproteins: a comparison of deformed-responsive elements. (2000) (32)
- Drosophila Homeobox Genes (1993) (32)
- A screen for modifiers of Deformed function in Drosophila. (1995) (30)
- Deformed expression in the Drosophila central nervous system is controlled by an autoactivated intronic enhancer. (1995) (29)
- Context-dependent regulation of Hox protein functions by CK2 phosphorylation sites (2008) (29)
- Hox Genes: It's All a Matter of Context (2002) (29)
- Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain (2000) (29)
- Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development (1993) (27)
- Minimizing off-target signals in RNA fluorescent in situ hybridization (2010) (24)
- Complete mutation analysis panel of the 39 human HOX genes. (2001) (23)
- Toll pathway is required for wound-induced expression of barrier repair genes in the Drosophila epidermis (2017) (23)
- Establishment and maintenance of position-specific expression of the Drosophila homeotic selector gene Deformed. (1990) (22)
- Association of a Drosophila transposable element of the roo family with chromosomal deletion breakpoints. (1983) (22)
- Structure and expression patterns of Drosophila TULP and TUSP, members of the tubby-like gene family (2002) (21)
- Molecular limits on the size of a genetic locus in Drosophila melanogaster. (1980) (21)
- Gene length may contribute to graded transcriptional responses in the Drosophila embryo. (2011) (21)
- Silencing of an abdominal Hox gene during early development is correlated with limb development in a crustacean trunk (2010) (19)
- Despite expression in embryonic visceral mesoderm, H2.0 is not essential for Drosophila visceral muscle morphogenesis. (1991) (19)
- The genome of the choanoflagellate Monosiga brevicollis and the origins of metazoan multicellularity (2008) (19)
- Model Organisms in the Study of Development and Disease (2016) (18)
- Three Drosophila Hox Complex microRNAs Do Not Have Major Effects on Expression of Evolutionarily Conserved Hox Gene Targets during Embryogenesis (2012) (15)
- Targeted ribozymes reveal a conserved function of the Drosophila paired gene in sensory organ development (1995) (13)
- Microinjection Wound Assay and In vivo Localization of Epidermal Wound Response Reporters in Drosophila Embryos. (2013) (10)
- SEGMENTATION OF NUCLEI IN CONFOCAL IMAGE STACKS USING PERFORMANCE BASED THRESHOLDING (2007) (10)
- High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes (2021) (9)
- Structural and functional aspects of the mammalian homeo-box sequences (1985) (8)
- Gap Peptides: A New Way to Control Embryonic Patterning? (2006) (6)
- Grainy head phosphorylation is essential for wound-dependent regeneration of an epidermal barrier but dispensable for embryonic barrier development (2010) (5)
- Regulating the expression and function of homeotic genes. (1991) (5)
- The expression of Drosophila melanogaster Hox gene Ultrabithorax is not overtly regulated by the intronic long noncoding RNA lncRNA:PS4 in a wild-type genetic background (2021) (2)
- Hox Genes and Body Plan: Evolution (2008) (1)
- Dissecting the evolutionary role of the Hox gene proboscipedia in Drosophila mouthpart diversification by full locus replacement (2021) (1)
- abdominal segment identity function . The regulation of empty spiracles by Abdominal-B mediates an References (2007) (1)
- Pattern formation and developmental mechanisms: good mileage from comparative studies in cell biology, gene regulation, development and evolution. (2005) (1)
- Flotillin2 inhibits the activity of an epidermal wound response sensor (2010) (0)
- Homeotic Proteins, Molecular Architects of Body Patterning (1998) (0)
- Homeo box genes and animal development (1988) (0)
- Akirin links Twist transcription factor activity with the Brahma chromatin remodeling complex during embryogenesis (2010) (0)
- ASNET: Actin-based network structure in the tunic of ascidian larva (2010) (0)
- Evolutionary change in developmental genetic networks (2004) (0)
- The role of zebrafish zic genes in neural crest development (2009) (0)
- Serine protease activation of the epidermal wound response in Drosophila (2010) (0)
- Counting Hox transcript numbers within single cells in fixed Drosophila embryos: Evidence for a stochastic mode of gene expression (2009) (0)
- In search of functional conservation for the animal epidermal integrity gene grainyhead in the fungus Neurospora crassa (2010) (0)
- Effects on Epidermal Actin Composition in Wounded Drosophila Grainy head Zygotic Mutants (2008) (0)
- Flotillin2 controls the spread of epidermal wound response in Drosophila (2009) (0)
- Molecular mechanism of wound-dependent Grh regulation (2009) (0)
- COLLECTIONS OF CLASSIFIERS TUNED FOR CELL FINDING WITH AN APPLICATION TO BUILDING DIGITAL CELL ATLASES OF DROSOPHILA EMBRYOS (2007) (0)
- Homeotic (Hox) genes (2014) (0)
- Segmental diversification of the posterior head is a part of a conserved genetic system for anterior-posterior patterning of a metameric animal body, in which homeotic selector genes play (2000) (0)
- From the editors (2005) (0)
- Co-option of an anteroposterior head axis gene network for proximodistal patterning of appendages in early bilaterian evolution (2010) (0)
- 3 Model Organisms in the Study of Development and Disease (2003) (0)
- Dual functions of the miR-10 locus miRNAs in refinement of Hox gene expression (2009) (0)
- Serine protease activation of epidermal wound response genes in Drosophila (2009) (0)
- Epidermal wound response activators and mechanisms of control (2011) (0)
- Correction for Bengoechea et al., p75 reduces β-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model (2009) (0)
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