William R. Roush

Q: What Schools Are Affiliated With William R. Roush

William R. Roush is affiliated with the following schools: Indiana University Bloomington, Indiana University, University of Michigan, State University of Campinas, University of California, Los Angeles, Massachusetts Institute of Technology, University of California, San Francisco, Brigham Young University, Harvard University

William R. Roush's AcademicInfluence.com Rankings

William R. Roush

Chemistry

#595

World Rank

#1034

Historical Rank

#275

USA Rank

Organic Chemistry

#84

World Rank

#117

Historical Rank

#34

USA Rank

chemistry Degrees

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Chemistry

Why Is William R. Roush Influential?

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According to Wikipedia, William R. Roush is an American organic chemist. He studied chemistry at the University of California Los Angeles and Harvard University . Following a year postdoctoral appointment at Harvard, he joined that faculty at the Massachusetts Institute of Technology. In 1987, Dr. Roush moved to Indiana University and was promoted to Professor in 1989 and Distinguished Professor in 1995. Two years later, he moved to the University of Michigan in Ann Arbor and served as the Warner Lambert/Parke Davis Professor of Chemistry. He served as chair of the University of Michigan's Department of Chemistry from 2002-2004. In 2004 Professor Roush relocated with his group to the Jupiter, Florida, campus of the Scripps Research Institute where he is currently an emeritus professor.

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William R. Roush's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (861)
Nucleophilic Phosphine Organocatalysis (2004) (743)
Horner-wadsworth-emmons reaction: Use of lithium chloride and an amine for base-sensitive compounds (1984) (618)
Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand (2011) (447)
Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. (2014) (279)
Asymmetric synthesis using diisopropyl tartrate modified (E)- and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes (1990) (247)
Diastereo- and enantioselective aldehyde addition reactions of 2-allyl-1,3,2-dioxaborolane-4,5-dicarboxylic esters, a useful class of tartrate ester modified allylboronates (1985) (210)
Systems analysis of intracellular pH vulnerabilities for cancer therapy (2018) (209)
Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (189)
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. (2010) (178)
Acyclic diastereoselective synthesis using tartrate ester-modified crotylboronates. Double asymmetric reactions with .alpha.-methyl chiral aldehydes and synthesis of the C(19)-C(29) segment of rifamycin S (1990) (177)
Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases (1998) (170)
Tris(dimethylamino)sulfonium Difluorotrimethylsilicate, a Mild Reagent for the Removal of Silicon Protecting Groups (1998) (162)
The vinylogous intramolecular Morita-Baylis-Hillman reaction: synthesis of functionalized cyclopentenes and cyclohexenes with trialkylphosphines as nucleophilic catalysts. (2002) (161)
CONCERNING THE DIASTEREOFACIAL SELECTIVITY OF THE ALDOL REACTIONS OF ALPHA-METHYL CHIRAL ALDEHYDES AND LITHIUM AND BORON PROPIONATE ENOLATES (1991) (157)
Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense. (2001) (156)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. (2019) (147)
Structure-Activity Relationships for Inhibition of Cysteine Protease Activity and Development of Plasmodium falciparum by Peptidyl Vinyl Sulfones (2003) (146)
Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer. (2019) (127)
Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. (2010) (123)
Stereochemistry of the reactions of substituted allylboronates with chiral aldehydes. Factors influencing aldehyde diastereofacial selectivity (1986) (122)
Enantioselective synthesis of 1,5-anti- and 1,5-syn-diols using a highly diastereoselective one-pot double allylboration reaction sequence. (2002) (118)
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes (2015) (118)
Directed openings of 2,3-epoxy alcohols via reactions with isocyanates: synthesis of (+)-erythro-dihydrosphingosine (1985) (110)
Enantioselective Total Synthesis of (-)-Chlorothricolide (1994) (99)
Asymmetric synthesis using tartrate ester modified allylboronates. 1. Factors influencing stereoselectivity (1990) (99)
Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus. (2007) (97)
Total synthesis of (-)-spinosyn A. (2004) (96)
Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist. (2011) (95)
A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. (2000) (94)
Total synthesis of (-)-bafilomycin A(1). (2002) (90)
Diisopropyl tartrate modified (E)-crotylboronates: highly enantioselective propionate (E)-enolate equivalents (2002) (89)
Relative rates of Michael reactions of 2'-(phenethyl)thiol with vinyl sulfones, vinyl sulfonate esters, and vinyl sulfonamides relevant to vinyl sulfonyl cysteine protease inhibitors. (2003) (89)
Enantioselective Total Synthesis of (−)-Chlorothricolide via the Tandem Inter- and Intramolecular Diels−Alder Reaction of a Hexaenoate Intermediate (1998) (87)
A Highly Stereoselective Synthesis of 2-Deoxy-β-glycosides Using 2-Deoxy-2-iodo-glucopyranosyl Acetate Donors (1999) (84)
Total synthesis of carbohydrates. 5. Stereochemistry of the epoxidations of acyclic allylic amides. Applications towards the synthesis of 2,3,6-trideoxy-3-aminohexoses (1987) (84)
Use of thallium(I) ethoxide in Suzuki cross coupling reactions. (2000) (82)
Reactions of diisopropyl tartrate modified allyl- and (E)- and (Z)-crotylboronates with .beta.-alkoxy-.alpha.-methylpropionaldehydes: a reagent-based solution to the acyclic dipropionate problem (1987) (80)
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase (2015) (79)
Asymmetric synthesis using tartrate ester modified allylboronates. 2. Single and double asymmetric reactions with alkoxy-substituted aldehydes (1990) (78)
Studies on the Synthesis of Nargenicin A1: Highly Stereoselective Synthesis of the Complete Carbon Framework via the Transannular Diels−Alder Reaction of an 18-Membered Macrolide (1996) (78)
Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle. (2015) (77)
In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi (2010) (77)
Regioselectivity of the reactions of trialkylaluminum reagents with 2,3-epoxyalcohols: Application to the synthesis of α-chiral aldehydes (1983) (75)
Intramolecular Diels–Alder Reactions (1991) (74)
Small-Molecule Inhibitors of Acetyltransferase p300 Identified by High-Throughput Screening Are Potent Anticancer Agents (2013) (74)
Stereoselective synthesis of (Z,E)-2-bromo-1,3-dienes via the palladium (O) catalyzed cross coupling reactions of 1,1-dibromoolefins and vinylboronic acids (1990) (72)
Solid-Phase Synthesis of 6-Deoxyoligosaccharides (1996) (72)
A STEREOCHEMICALLY GENERAL SYNTHESIS OF 2-DEOXYHEXOSES VIA THE ASYMMETRIC ALLYLBORATION OF 2,3-EPOXY ALDEHYDES (1991) (72)
Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain. (2001) (71)
Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane. (2009) (70)
Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-δ-stannyl-anti-homoallylic alcohols via aldehyde crotylboration. (2011) (70)
Enantioselective synthesis of 2-alkyl-5-methylene-1,3-dioxolan-4-ones and exo-selective Diels-Alder reactions with cyclopentadiene (1992) (68)
Use of Recombinant Entamoeba histolytica Cysteine Proteinase 1 To Identify a Potent Inhibitor of Amebic Invasion in a Human Colonic Model (2007) (68)
Diisopropyl tartrate modified (E)-γ-[(cyclohexyloxy)dimethylsilyl]- and (E)-γ-(dimethylphenylsilyl)allylboronates: Chiral Reagents for the Enantio- and Diastereoselective synthesis of anti 1,2-diols and 2-butene-1,4-diols via the formal α- and γ-hydroxyallylation of aldehydes (1992) (67)
Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth (2015) (67)
Studies on the Synthesis of Aureolic Acid Antibiotics: Highly Stereoselective Synthesis of Aryl 2-Deoxy-.beta.-glycosides via the Mitsunobu Reaction and Synthesis of the Olivomycin A-B Disaccharide (1995) (66)
N,N'-dibenzyl-N,N'-ethylenetartramide: a rationally designed chiral auxiliary for the allylboration reaction (1988) (66)
Studies of an intramolecular Diels-Alder approach to the nargenicins: involvement of boatlike transition states in the cyclizations of substituted 1,7,9-decatrien-3-ones (1989) (65)
Drug Strategies Targeting CYP51 in Neglected Tropical Diseases (2014) (64)
Enantioselective synthesis of the bottom half of chlorothricolide. II: A comparative study of substituent effects on the stereoselectivity of the key intramolecular Diels-Alder reaction (1988) (64)
Enantioselective synthesis of anti- and syn-homopropargyl alcohols via chiral Brønsted acid catalyzed asymmetric allenylboration reactions. (2012) (64)
Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors. (1998) (63)
Recent Applications of the Allylation Reaction to the Synthesis of Natural Products (2007) (62)
Total synthesis of carbohydrates. 2. Regiochemical control of nucleophilic ring opening of acylated 2,3-epoxy alcohols (1983) (62)
Recent advances in the synthesis, design and selection of cysteine protease inhibitors. (2002) (61)
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates (2017) (61)
Application of .eta.4-Diene Iron Tricarbonyl Complexes in Acyclic Stereocontrol: Asymmetric Synthesis of the as-Indacene Unit of Ikarugamycin (A Formal Total Synthesis) (1994) (60)
A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A (1989) (59)
Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases. (2015) (59)
Enantioselective synthesis of the bottom half of chlorothricolide. 3. Studies of the steric directing group strategy for stereocontrol in intramolecular Diels-Alder reactions (1991) (59)
Application of the intramolecular vinylogous Morita-Baylis-Hillman reaction toward the synthesis of the spinosyn A tricyclic nucleus. (2002) (58)
A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target* (2010) (58)
Total synthesis of carbohydrates. 3. Efficient enantioselective syntheses of 2,6-dideoxyhexoses (1983) (58)
Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences. (2009) (58)
Total synthesis of (-)-spinosyn A: examination of structural features that govern the stereoselectivity of the key transannular Diels-Alder reaction. (2008) (56)
Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties. (2013) (56)
A highly stereoselective synthesis of aryl 2-deoxy-.beta.-glycosides via the Mitsunobu reaction (1991) (56)
Stereochemistry of Vinyl Cuprate Additions to Carbohydrate-Derived Enones and α,β-Unsaturated Esters (1983) (56)
Synthetic studies toward FR182877. Remarkable solvent effect in the vinylogous morita-baylis-hillman cyclization. (2003) (54)
Studies on the Synthesis of 2,6-Disubstituted Dihydropyrans: Intervention of Oxonia-Cope Rearrangements in the Lewis Acid Mediated Cyclodehydrative Reactions of Aldehydes and β-Hydroxyallylsilanes (2001) (53)
Total synthesis of +-superstolide A. (2008) (53)
Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions. (2012) (53)
Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system (1981) (53)
Remarkable phosphine-effect on the intramolecular aldol reactions of unsaturated 1,5-diketones: highly regioselective synthesis of cross-conjugated dienones. (2005) (52)
Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. (2005) (52)
A FORMAL TOTAL SYNTHESIS OF (+)-TETRONOLIDE, THE AGLYCON OF THE TETROCARCINS : ENANTIO- AND DIASTEREOSELECTIVE SYNTHESES OF THE OCTAHYDRONAPHTHALENE ( BOTTOM-HALF) AND SPIROTETRONATE (TOP-HALF) FRAGMENTS (1997) (52)
Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift. (2010) (51)
Synthesis of the C(1)-C(25) fragment of amphidinol 3: application of the double-allylboration reaction for synthesis of 1,5-diols. (2005) (50)
Synthesis of verrucarin B (1983) (49)
2-Deoxy-2-iodo- and 2-deoxy-2-bromo-alpha-glucopyranosyl trichloroacetimidates: highly reactive and stereoselective donors for the synthesis of 2-deoxy-beta-glycosides. (1999) (48)
Application of the steric directing group strategy to the stereoselective synthesis of the octahydronaphthalene substructure of kijanolide and tetronolide (1993) (48)
Studies on the total synthesis of chlorothricolide: stereochemical aspects of the intramolecular Diels-Alder reactions of methyl undeca-2,8,10-trienoates (1981) (47)
Total synthesis of (+)-13-deoxytedanolide. (2005) (47)
Synthesis of the C11-C29 fragment of amphidinolide F. (2004) (47)
4,5-Diisopropyl-B-[(E)-[(3‘-menthofuryl)dimethylsilyl]allyl]-1,3,2- dioxaborolane, an Improved Chiral Reagent for the Anti α-Hydroxyallylation of Aldehydes: Application to the Enantioselective Synthesis of (−)-Swainsonine (1997) (46)
Highly (E)-selective BF(3).Et(2)O-promoted allylboration of chiral nonracemic alpha-substituted allylboronates and analysis of the origin of stereocontrol. (2010) (46)
A highly diastereo- and enantioselective synthesis of the top half of kijanolide (1993) (46)
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. (2015) (45)
1.1 – Allyl Organometallics (1991) (45)
Studies on the synthesis of pectenotoxin II: synthesis of a C(11)-C(26) fragment precursor via [3 + 2]-annulation reactions of chiral allylsilanes. (2001) (43)
Polymer - bound tosyl azide (1974) (43)
Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide. (2008) (43)
Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence. (2013) (43)
A highly stereoselective synthesis of the octahydronaphthalene subunit of kijanolide and tetronolide (1988) (42)
4-Aminopyridyl-Based CYP51 Inhibitors as Anti-Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency (2014) (42)
Stereoselective synthesis of 2-deoxy-β-glycosides from glycal precursors. 1. Stereochemistry of the reactions of d-glucal derivatives with phenylsulfenyl chloride and phenylselenenyl chloride (1997) (42)
Asymmetric Allylboration of 2-N,3-O-Isopropylidene-N-Boc-L-serinal: Diastereoselective Synthesis of the Calicheamicin .gamma.1I Amino Sugar (1995) (41)
A Three-Component Coupling Strategy for Tetrahydrofuran Synthesis: Application of the Diisopropyl Tartrate Modified (E)-γ-(Dimethylphenylsilyl)allylboronate as an α,γ-Allyl Dianion Equivalent (2000) (41)
Synthesis of the C(29)-C(45) bis-pyran subunit (E-F) of spongistatin 1 (Altohyrtin A). (2000) (41)
Therapeutic targeting of casein kinase 1δ in breast cancer (2015) (41)
Stereoselective synthesis of the C(1)-C(11) fragment of peloruside A. (2005) (41)
Anti-malarial drug development using models of enzyme structure. (1994) (41)
Studies on the synthesis of (-)-spinosyn a: application of the steric directing group strategy to transannular Diels-Alder reactions. (2002) (40)
Diastereoselective synthesis of the C(17)-C(28) fragment (the C-D spiroketal unit) of spongistatin 1 (altohyrtin A) via a kinetically controlled iodo-spiroketalization reaction. (2002) (40)
Use of metal carbonyl complexes to achieve high enantioselectivity in the asymmetric allylboration of unsaturated aldehydes (1990) (40)
Stereochemistry of the Allylation and Crotylation Reactions of α-Methyl-β-hydroxy Aldehydes with Allyl- and Crotyltrifluorosilanes. Synthesis of anti,anti-Dipropionate Stereotriads and Stereodivergent Pathways for the Reactions with 2,3-anti- and 2,3-syn-α-Methyl-β-hydroxy Aldehydes (2003) (39)
Synthesis of C-D-E trisaccharide precursors of olivomycin A. (1992) (39)
Total synthesis of cochleamycin A. (2004) (39)
Stereoselective synthesis of 2-deoxy-β-glycosides from glycal precursors. 2. Stereochemistry of glycosidation reactions of 2-thiophenyl- and 2-selenophenyl-α-d-gluco-pyranosyl donors (1997) (39)
Total Synthesis of (-)-Bafilomycin A1 : Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions. (1999) (39)
Synthesis of macrocyclic trypanosomal cysteine protease inhibitors. (2008) (39)
Stereoselective synthesis of 2-deoxy-beta-galactosides via 2-deoxy-2-bromo- and 2-deoxy-2-iodo-galactopyranosyl donors. (2003) (39)
Rational development of 4-aminopyridyl-based inhibitors targeting Trypanosoma cruzi CYP51 as anti-chagas agents. (2013) (39)
Generation of stereochemically defined tetrasubstituted enolborinates by 1,4-hydroboration of α,β-unsaturated morpholine carboxamides with (diisopinocampheyl)borane. (2013) (38)
Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation. (2012) (38)
Total synthesis of formamicin. (2004) (38)
Synthesis and Structure–Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitors (2014) (38)
Studies on the synthesis of bafilomycin A(1): stereochemical aspects of the fragment assembly aldol reaction for construction of the C(13)-C25) segment. (2002) (38)
Application of tartrate ester modified allylic boronates in organic synthesis: an efficient, highly stereoselective synthesis of the carbon(19)-carbon(29) segment of rifamycin S (1987) (38)
Asymmetric allylborations of diene aldehyde Fe(CO)3 derivatives: Efficient kinetic resolution of racemic complexes and the highly enantiotopic group and face selective allylboration of a meso substrate (1990) (37)
Stereoselective syntheses of the C(1)-C(9) fragment of amphidinolide C. (2008) (37)
A stereorational total synthesis of (−)-ptilocaulin (1985) (37)
Concerning the origin of the high beta-selectivity of glycosidation reactions of 2-deoxy-2-iodo-glucopyranosyl trichloroacetimidates. (2002) (37)
Studies on the Synthesis of Tedanolide: Synthesis of the C(5)−C(21) Segment via a Highly Stereoselective Fragment Assembly Aldol Reaction of a Chiral β,γ-Unsaturated Methyl Ketone (1999) (36)
Cathepsins X and B can be differentiated through their respective mono- and dipeptidyl carboxypeptidase activities. (2001) (36)
Diisopropyl tartrate (E)-γ-(dimethylphenylsilyl)allylboronate, a chiral allylic alcohol β-carbanion equivalent for the enantioselective synthesis of 2-butene-1,4-diols from aldehydes (1990) (36)
Studies on the Synthesis of Aureolic Acid Antibiotics: Acyloin Glycosidation Studies. (1996) (36)
[(Z)-.gamma.-[(Diisopropylidene-.alpha.-D-mannopyranosyl)oxy]allyl]tributylstannane: A New Chiral Reagent for the Asymmetric .alpha.-Hydroxyallylation of Aldehydes (1994) (36)
Total Synthesis of Olivomycin A (1999) (36)
The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells. (2020) (36)
Synthesis of the C(43)-C(67) fragment of amphidinol 3. (2005) (35)
Chiral Brønsted acid catalyzed enantioselective synthesis of anti-homopropargyl alcohols via kinetic resolution-aldehyde allenylboration using racemic allenylboronates. (2013) (35)
Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment. (2008) (35)
Total synthesis of (.+-.)-dendrobine (1978) (35)
N,N'-Bis(2,2,2-trifluoroethyl)-N,N'-ethylenetartramide: An Improved Chiral Auxiliary for the Asymmetric Allylboration Reaction (1995) (35)
Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1 (2015) (34)
Studies on the synthesis of landomycin A. Synthesis of the originally assigned structure of the aglycone, landomycinone, and revision of structure. (2004) (34)
Total synthesis of carbohydrates: stereoselective syntheses of 2,6-dideoxy-D-arabino-hexose and 2,6-dideoxy-D-ribo-hexose (1982) (34)
Identification of novel, exosite-binding matrix metalloproteinase-13 inhibitor scaffolds. (2011) (34)
Synthesis of (+)-bullatacin via the highly diastereoselective [3+2] annulation reaction of a racemic aldehyde and a nonracemic allylsilane. (2005) (34)
The origin of diastereofacial control in allylboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen. (2002) (33)
Synthesis of antibiotic X-14547A (1984) (33)
Enantio- and diastereoselective synthesis of (E)-1,5-syn-diols: application to the synthesis of the C(23)-C(40) fragment of tetrafibricin. (2011) (33)
A highly stereoselective total synthesis of the natural enantiomer of olivin (1987) (32)
Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin. (2007) (32)
HIGHLY SELECTIVE LEWIS ACID CATALYZED DIELS-ALDER REACTIONS OF ACYCLIC (Z)-1,3-DIENES (1997) (32)
Chemistry and biology of macrolide antiparasitic agents. (2011) (32)
Diastereoselective synthesis of the cis-octahydronaphthalene nucleus of superstolides A and B (1996) (31)
Total synthesis of (−)-ptilocaulin (1984) (31)
Total synthesis of (-)-tirandamycin C. (2012) (31)
Concerning the Synthesis of the Elusive anti,anti-Dipropionate Stereotriad via the Crotylation of β-Hydroxy α-Methyl Aldehydes with (Z)-Crotyltrifluorosilane. Application to the Synthesis of the C(7)−C(16) Segment of Zincophorin (1998) (31)
Synthesis and Diels-Alder reactions of 2-alkyl-5-methylene-1,3-dioxolan-4-ones and 2-alkyl-3-acyl-5-methylene-1,3-oxazolidin-4-ones: Highly exo and diastereoface selective chiral ketene equivalents (1989) (31)
[(E)-γ-(Dimethylphenylsilyl)allyl]diisopinocampheylborane: a highly enantioselective reagent for the synthesis of anti-β-hydroxyallylsilanes (2000) (30)
Modulators of STAT Transcription Factors for the Targeted Therapy of Cancer (STAT3 Inhibitors) (2011) (30)
Efficient protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds using tetrabutylammonium fluoride. (2005) (30)
Studies on the Synthesis of Olivin: Diastereoselective Synthesis of a Functionalized D-Fucose Derivative (1983) (30)
Enantio- and diastereoselective synthesis of cyclic beta-hydroxy allylsilanes via sequential aldehyde gamma-silylallylboration and ring-closing metathesis reactions. (2003) (30)
Diisopropyl tartrate modified (E)-γ-[(cyclohexyloxy)dimethylsilyl-allylboronate, a chiral reagent for the stereoselective synthesis of anti 1,2-diols via the formal α-hydroxyallylation of aldehydes (1990) (30)
TOTAL SYNTHESIS OF (+)-DAMAVARICIN D (1997) (30)
Total Synthesis of Amphidinolide E and Amphidinolide E Stereoisomers. (2007) (29)
Enantioselective synthesis using diisopropyl tartrate modified (E)- and (Z)-crotylboronates: Reactions with achiral aldehydes (1988) (29)
2-Deoxy-2-iodo-alpha-mannopyranosyl and -talopyranosyl acetates: highly stereoselective glycosyl donors for the synthesis of 2-deoxy-alpha-glycosides. (1999) (29)
Synthesis of the C(1)−C(15) segment of streptovaricin D (1989) (29)
Enantioselective synthesis of (E)-δ-silyl-anti-homoallylic alcohols via an enantiodivergent hydroboration-crotylboration reaction of a racemic allenylsilane. (2013) (29)
Enantioselective syntheses of syn- and anti-β-hydroxyallylsilanes via allene hydroboration-aldehyde allylboration reactions. (2011) (29)
Origin of thermodynamic versus kinetic control of allene hydroboration with 9-borabicyclo[3.3.1]nonane and 10(R)-trimethylsilyl-9-borabicyclo[3.3.2]decane. (2009) (29)
2-Deoxy-2-iodo-β-glucopyranosyl Fluorides: Mild and Highly Stereoselective Glycosyl Donors for the Synthesis of 2-Deoxy-β-glycosides from β-Hydroxy Ketones (2003) (28)
Enantioselective synthesis of the bottom-half of chlorothricolide (1985) (28)
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds. (2008) (28)
Synthesis of epoxytrichothecenes: verrucarin J and verrucarin J isomers (1984) (28)
Design and synthesis of dipeptidyl α′,β′-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain (1998) (28)
Highly stereoselective substitution reactions of functionalized η4-[3(E),5(E)-heptadien-2-ol]iron tricarbonyl complexes (1994) (28)
Studies on the synthesis of kijanolide: synthesis of the 2-acyl spirotetronate and investigations concerning the coupling of the top and bottom half fragments (1993) (28)
Hydrofluoric acid catalyzed intramolecular Diels-Alder reactions (1984) (28)
Asymmetric allylborations of 3-decynal dicobalt hexacarbonyl: cobalt induced reversal of enantioselectivity and applications to highly diastereoselective intramolecular pauson-khand reactions (1991) (28)
Chemically Programmed Bispecific Antibodies in Diabody Format * (2016) (27)
Total synthesis of (+)-superstolide A. (2008) (27)
Toward the synthesis of mycalamides A, B and onnamide A: a highly stereoselective synthesis of the trioxadecalin ring system (1993) (27)
Enantioselective synthesis of (+)-crocacin C. An example of a highly challenging mismatched double asymmetric δ-stannylcrotylboration reaction. (2012) (27)
Stereoselective synthesis of the C(13)–C(25) segment of bafilomycin A1 (1992) (26)
Diastereoselective synthesis of the endo- and exo-spirotetronate subunits of the quartromicins. The first enantioselective Diels-Alder reaction of an acyclic (Z)-1,3-diene. (2002) (26)
Total synthesis of mycalamide A and 7-epi-mycalamide A. (2000) (26)
Iodoacetoxylation of glycals using cerium(IV) ammonium nitrate, sodium iodide, and acetic acid: stereoselective synthesis of 2-deoxy-2-iodo-alpha-mannopyranosyl acetates. (1999) (26)
A HIGHLY STEREOSELECTIVE SYNTHESIS OF THE AB DISACCHARIDE UNIT OF OLIVOMYCIN A (1991) (26)
[3 + 2]-annulation reactions of chiral allylsilanes and chiral aldehydes. studies on the synthesis of bis-tetrahydrofuran substructures of annonaceous acetogenins. (2005) (26)
Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. (2015) (26)
Studies on the total synthesis of sesbanimide: A highly diastereoselective synthesis of the ab ring system (1986) (25)
Inhibitors of SARS-CoV entry – Identification using an internally-controlled dual envelope pseudovirion assay (2011) (25)
Enantio- and Diastereoselective Synthesis of syn-β-Hydroxyallylsilanes via a Chiral (Z)-γ-Silylallylboronate (2007) (25)
Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. (2017) (25)
Studies on the synthesis of tedanolide. 2. Stereoselective synthesis of a protected C(1)-C(12) fragment. (2002) (25)
Crotylboron-based synthesis of the polypropionate units of chaxamycins A/D, salinisporamycin, and rifamycin S. (2013) (24)
Studies on the synthesis of landomycin A: synthesis and glycosidation reactions of L-rhodinosyl acetate derivatives. (2001) (24)
Towards the synthesis of spongistatin 1: Diastereoselective synthesis of the C(36)–C(45) subunit (1999) (24)
Highly stereoselective and modular syntheses of 10-hydroxytrilobacin and three diastereomers via stereodivergent [3 + 2]-annulation reactions. (2008) (24)
Synthesis of trichoverrol B (1983) (24)
Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones. (2011) (23)
Common-intermediate strategy for synthesis of conduritols and inositols via beta-hydroxy cyclohexenylsilanes. (2003) (23)
Diisopropyl tartrate-modified (E)-γ-[(menthofuryl)dimethylsilyl]-allyl boronate, an improved chiral reagent for the anti α-hydroxyallylation of aldehydes. Application to the enantioselective synthesis of (−)-swainsonine (1995) (23)
Enantio- and stereoselective syntheses of the dihydroxyoctadienoic acid framents of the roridins and trichoverrins (1982) (23)
Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine. (2013) (23)
Discovery of Inverse Agonists for the Liver Receptor Homologue-1 (LRH1; NR5A2) (2011) (23)
Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases. (2017) (23)
Synthesis of the C(26)-C(42) and C(43)-C(67) pyran-containing fragments of amphidinol 3 via a common pyran intermediate. (2008) (23)
Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation (2019) (23)
Synthesis of precursors of the agalacto (exo) fragment of the quartromicins via an auxiliary-controlled exo-selective Diels-Alder reaction. (2006) (23)
Characterization of Selective Exosite-Binding Inhibitors of Matrix Metalloproteinase 13 That Prevent Articular Cartilage Degradation in Vitro (2014) (23)
Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain. (2016) (23)
Stereochemistry of crotylboronate additions to .alpha.,.beta.-dialkoxy aldehydes (1985) (23)
Diastereoselective aldol reactions of chiral aldehydes and chiral methyl ketones: Dependence of stereoselectivity on the metal enolate, the aldehyde 2,3-stereochemistry, and the aldehyde β-alkoxy protecting group (1995) (23)
Binding Mode and Potency of N-Indolyloxopyridinyl-4-aminopropanyl-Based Inhibitors Targeting Trypanosoma cruzi CYP51 (2014) (22)
Concerning the diastereofacial selectivity of aldol reactions of chiral methyl ketone enolates : evidence for remote chelation in the bafilomycin aldol reaction (1993) (22)
Total synthesis of amphidinolide E. (2006) (22)
Casein Kinase 1δ-dependent Wee1 Protein Degradation* (2014) (22)
Enantioselective synthesis of (Z)-1,2-anti-2,5-anti-triol monosilyl ethers using a cross-metathesis allylboration sequence. (2010) (22)
Studies toward the total synthesis of angelmicin B (hibarimicin B): synthesis of a model CD-D' arylnaphthoquinone. (2004) (22)
Stereoselective synthesis of functionalized precursors of the CDEF and CDE 2,6-dideoxy-tetra- and trisaccharide units of durhamycins A and B. (2003) (22)
Highly stereoselective synthesis of α-L-olivomycosides via trimethylsilyl triflate mediated glycosidations of 1-O-acetyl-4-O-isobutyryl-2,6-dideoxy-2-iodo-3-C-methyl-α-L-mannopyranose (1993) (22)
STUDIES ON THE TOTAL SYNTHESIS OF CHLOROTHRICOLIDE: STEREOCHEMICAL ASPECTS OF THE INTRAMOLECULAR DIELS‐ALDER REACTIONS OF METHYL UNDECA‐2,8,10‐TRIENOATES (1981) (21)
Design, Synthesis and Evaluation of d-Homophenylalanyl Epoxysuccinate Inhibitors of the Trypanosomal Cysteine Protease Cruzain (2000) (21)
Second generation synthesis of the quartromicin spirotetronic acid subunits via a Claisen rearrangement-intramolecular aldol sequence (1997) (21)
An improved synthesis of naphthoate precursors to olivin (1992) (21)
Development of a Double Allylboration Reagent Targeting 1,5-syn-(E)-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin. (2011) (20)
Trichothecene metabolism studies: isolation and structure determination of 15-acetyl-3.alpha.-(1'.beta.-D-glucopyranosiduronyl)scirpen-3,4.beta.,15-triol (1985) (20)
Expanding the Binding Envelope of CYP51 Inhibitors Targeting Trypanosoma cruzi with 4‐Aminopyridyl‐Based Sulfonamide Derivatives (2014) (20)
Studies on the total synthesis of formamicin: synthesis of the C(1)-C(11) fragment. (2001) (20)
Alkyldimethylpyrazines in the Defensive Spray of Phyllium westwoodii: A First for Order Phasmatodea (2009) (20)
Solid-state and solution conformational analysis of tartrate-derived 1,3-dioxolanes and 1,3,2-dioxaborolanes (1992) (19)
Total synthesis of the formamicin aglycon, formamicinone. (2003) (19)
Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes (2017) (19)
Synthesis and transannular diels-alder reactions of (E,E,E)-cyclotetradeca-2,8,10-trienones (1993) (19)
Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots (2016) (19)
Synthesis of the C(21)-C(26) fragment of superstolide A: concerning the stereochemistry of (E)-crotylboration reactions of alaninal derivatives. (2003) (19)
Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester. (2013) (19)
Thermodynamic control of 1,3-boratropic shifts of α- and γ-stannyl-substituted allylboranes: hyperconjugation outweighs steric effects. (2011) (19)
COBRA: implications for emergency medicine. (1988) (19)
Synthesis of 2-epi-amphidinolide E: an unexpected and highly selective C(2)inversion during an esterification reaction. (2007) (19)
Stereoselective synthesis of syn,syn- and syn,anti-1,3,5-triols via intramolecular hydrosilylation of substituted pent-3-en-1,5-diols. (2009) (19)
A stereochemically general synthesis of methyl 2,4,6-trideoxy-4-methylthio-α-D-ribo-pyranoside, the thio sugar of esperamicin A1 (1994) (19)
Total synthesis of the AB disaccharide unit of olivomycin A (1986) (18)
R-Configuration of 4-Aminopyridyl-Based Inhibitors of CYP51 Confers Superior Efficacy Against Trypanosoma cruzi. (2014) (18)
Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin. (2011) (18)
An NMR method for assigning relative stereochemistry to beta-hydroxy ketones deriving from aldol reactions of methyl ketones. (2002) (18)
Methodology for the synthesis of the acyclic portions of verrucarins A and J (1982) (18)
Diastereoselective synthesis of the top half of Kijanolide (1989) (18)
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection (2017) (18)
Highly Diastereoselective Synthesis of Pederic Acid Derivatives. (1997) (17)
Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer. (2017) (17)
Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. (2019) (17)
Organic syntheses : an annual publication of satisfactory methods for the preparation of organic chemicals (1954) (17)
Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri. (2018) (17)
Lewis acid catalyzed intramolecular Diels-Alder reactions of acyclic (Z)-substituted 1,3-dienes. (2001) (17)
Structure activity studies of a novel cytotoxic benzodiazepine. (2003) (16)
ANTIBIOTIC X-14547A: TOTAL SYNTHESIS OF THE RIGHT-HAND HALF (1981) (16)
Synthesis of the bottom half of chlorothricolide (1982) (16)
Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (16)
Stereoselective synthesis of the octahydronaphthalene unit of integramycin via an intramolecular Diels-Alder reaction. (2005) (16)
Synthesis of the Naphthoquinone Nucleus of Awamycin (1995) (16)
Enantioselective synthesis of the top half of tetronolide (1992) (16)
Activating agents and protecting groups (1999) (16)
Acute urinary retention. (1988) (16)
Diastereoselective synthesis of N-benzoyl mycalamine, the fully elaborated trioxadecalin nucleus of mycalamide. A. Control of the key N-acyl aminal stereocenter via carbamate acylation (1995) (15)
An Ultra-High Throughput Cell-Based Screen for Wee1 Degradation Inhibitors (2010) (15)
Concerning the selective protection of (Z)-1,5-syn-ene-diols and (E)-1,5-anti-ene-diols as allylic triethylsilyl ethers. (2007) (15)
Hrr 25 / CK 1-directed release of Ltv 1 from pre-40 S ribosomes is necessary for ribosome assembly and cell growth (2015) (15)
Further stereochemical aspects of intramolecular Diels-Alder reactions in the undeca-2,8,10-trienoate ester series (1982) (15)
Enantio- and Diastereoselective Synthesis of 1,5-syn-(Z)-Amino Alcohols via Imine Double Allylboration: Synthesis of trans-1,2,3,6-Tetrahydropyridines and Total Synthesis of Andrachcine. (2017) (15)
Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation. (2016) (15)
Synthesis of the C(3)C(15) segment of rutamycin B via a C(8)C(9) fragment assembly aldol reaction: Metal dependence of the aldehyde and enolate diastereofacial selectivities (1995) (14)
Studies on the Synthesis of Chlorothricolide: Diastereo- and Enantioselective Syntheses of Model Top-Half Spirotetronate Units (1998) (14)
Highly diastereoselective synthesis of propargylic 1,2-anti-diol derivatives using alpha-alkoxypropargylstannanes. (2001) (14)
Synthesis of the C(2)-C(13) fragment (the A-B spiroketal unit) of spongistatin 1 (altohyrtin A): use of a common intermediate for the synthesis of both spongistatin spiroketals. (2002) (14)
Trichothecene metabolism studies. 2. Structure of 3α-(1″gb-D-glucopyranosiduronyl)-8α-isovaleryloxy-scirpen-3,4β, 15-triol 15-acetate produced from T-2 toxin (1985) (14)
Studies on the synthesis of nargenicin A1. An example of anintramolecular diels-alder reaction that proceeds with a boat-likeconformation of the connecting chain (1987) (14)
Studies on the synthesis of apoptolidin A. 2. Synthesis of the disaccharide unit. (2008) (14)
Studies on the synthesis of the quartromicins: partial stereochemical assignment of quartromicins A3 and D3 and diastereoselective synthesis of the endo- and exo-spirotetronate subunits (2002) (14)
Effect of dienophile activating group on the stereoselectivity of the intramolecular diels-alder reaction (1987) (14)
(Diisopinocampheyl)borane-mediated reductive aldol reactions of acrylate esters: enantioselective synthesis of anti-aldols. (2013) (14)
Probing the Lewis acid-catalyzed intramolecular Diels-Alder cyclizations of allylic alkoxy-substituted (Z)-1,3-dienes. (2003) (14)
Towards the Synthesis of Aureolic Acid Analogue Conjugates: Synthesis and Glycosidation Reactions of 3-O-Acetyl-4-azido-2,4,6-trideoxy-L-glucopyranose Derivatives (2002) (14)
Experimental evidence for chair-like transition states in aldol reactions of methyl ketone lithium enolates: stereoselective synthesis and utilization of a deuterium-labeled enolate as a probe of reaction stereochemistry. (2005) (14)
Enantio- and diastereoselective synthesis of syn-β-hydroxy-α-vinyl carboxylic esters via reductive aldol reactions of ethyl allenecarboxylate with 10-TMS-9-Borabicyclo[3.3.2]decane and DFT analysis of the hydroboration pathway. (2013) (14)
Studies on the Synthesis of the Mycalamides: Stereocontrolled Synthesis of a Model N-Glycosylpederamide via a Stereoselective Aldol Reaction (1998) (14)
In Silico HTS and Structure Based Optimization of Indazole-Derived ULK1 Inhibitors. (2017) (14)
Development of matrix metalloproteinase-13 inhibitors - A structure-activity/structure-property relationship study. (2018) (13)
STEREOCHEMICAL ASPECTS OF THE INTRAMOLECULAR DIELS-ALDER REACTIONS OF METHYL (E,E,E)- AND (Z,E,E)-6-ALKOXY-11-METHYLDODECA-2,7,9-TRIENOATE (1979) (13)
Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts. (2016) (13)
Synthesis of mycarose and epi-axenose from non-carbohydrate precursors. (1985) (13)
An intramolecular Diels-Alder approach to the spirotetronic acid subunits of the quartromicins (1997) (13)
Asymmetric synthesis of the hydroxylamino sugar of calicheamicin (1994) (13)
Enantiodivergent hydroboration reactions of a racemic allenylsilane with diisopinocampheylborane and Curtin-Hammett controlled double asymmetric crotylboration reactions of (S)-E-αphenyldimethylsilyl( d diisopinocampheyl)-crotylborane. (2013) (13)
Highly stereoselective 1,4-addition reactions of alkylidene malonate substituted η4-(1,3-butadienyl)iron(tricarbonyl) complexes (1994) (13)
Trichothecene degradation studies. II: Synthesis of [13-14C]anguidine (1987) (13)
Concerning the application of the 1H NMR ABX analysis for assignment of stereochemistry to aldols deriving from aldehydes lacking beta-branches. (2005) (13)
Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases. (1999) (13)
Enantioselective synthesis of alpha-methylene-beta-hydroxy carboxylic acid derivatives via a diastereoselective aldol/beta-elimination sequence: application to the C(15)-C(21) fragment of tedanolide C. (2010) (13)
Studies on the synthesis of quartromicins a(3) and d(3): synthesis of the vertical and horizontal bis-spirotetronate fragments. (2006) (13)
Optimization and Characterization of an Inhibitor for NADPH Oxidase 1 (NOX-1) (2011) (13)
Diastereoselective synthesis of the trans-anti-cis-decahydro-as-indacene ring system via the transannular Diels-Alder reaction of a functionalized (E,E,E)-cyclododeca-1,6,8-triene (1996) (13)
The asymmetric allylboration reaction: dependence of rate and enantioselectivity on the chiral auxiliary (1989) (13)
Studies on the synthesis of durhamycin A: stereoselective synthesis of a model aglycone. (2008) (13)
Siloxacyclopentenes as dienophile-linked directing groups in intramolecular Diels-Alder reactions. (2008) (12)
Studies of fragment assembly aldol reactions of chiral aldehydes and chiral methyl ketones: stereoselective synthesis of the C(13)–C(25) segment of scytophycin C (1999) (12)
Studies on the Synthesis of Reidispongiolide A: Stereoselective Synthesis of the C(22)-C(36) Fragment. (2011) (12)
Diethyl [(phenylsulfonyl)methyl]phosphonate: (Phosphonic acid, [(phenylsulfonyl)methyl]-, diethyl ester) (2002) (12)
Copper(I) Chloride (2017) (12)
Diastereo- and enantioselective synthesis of (E)-2-Methyl-1,2-syn- and (E)-2-Methyl-1,2-anti-3-pentenediols via allenylboronate kinetic resolution with ((d)Ipc)2BH and aldehyde allylboration. (2012) (12)
Synthesis of the A-B subunit of angelmicin B. (2005) (12)
Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation. (2017) (12)
Preparation and use of N, N'-di-BOC-n -triflylguanidine: (Carbamic acid, [[(trifluoromethyl)sulfonyl]carbonimidoyl]bis-, bis(1,1-dimethylethyl) ester) (2002) (12)
Intramolecular Diels-Alder reactions of siloxacyclopentene constrained trienes. (2007) (12)
Total synthesis of verrucarol: a stereoselective synthesis of 13,14-dinor-15-hydroxytrichothec-9-ene (1980) (11)
Diastereofacially selective enolate Claisen rearrangements of [4−7-η4-(1-acyloxy-2,4,6-octatrienyl)]tricarbonyliron complexes (1997) (11)
Analytical resolution of secondary methyl ethers by chiral complexation gas chromatography (1987) (11)
Studies on the synthesis of the decahydro-as-indacene ring system of (-)-spinosyn A via transannular Diels-Alder reactions of substituted (E,E,E)-cyclododeca-1,6,8-trienes (2000) (11)
Concerning the synthesis of the tedanolide C(13)-C(23) fragment via anti-aldol reaction. (2008) (11)
Improved synthesis of the perhydroindenone precursor of dendrobine (1980) (10)
Dowex ion‐exchange resins (2006) (10)
Total synthesis of biologically active natural products. (2008) (10)
An improved synthesis of the (E,Z)-dienoate precursor of (+)-damavaricin D via a vinylogous Horner-Wadsworth-Emmons reaction (1999) (10)
Trichothecene degradation studies. 3. Synthesis of 12,13-deoxy-12,13-methanoanguidine and 12-epianguidine, two optically active analogs of the epoxytrichothecene mycotoxin anguidine (1987) (9)
Partial stereochemical assignment of quartromicins A3 and D3. (2002) (9)
Synthesis of 2,6-trans-disubstituted 5,6-dihydropyrans from (Z)-1,5-syn-endiols (2005) (9)
Enantioselective synthesis of the C1-C11 fragment of tedanolide C. (2013) (9)
Trichothecene degradation studies: synthesis of 12,13-deoxyanguidine and 12,13-deoxyverrucarol (1985) (9)
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis (2021) (9)
Synthesis of naphthyl A–B disaccharides corresponding to olivomycin A and mithramycin (1993) (9)
Defensive Spiroketals from Asceles glaber (Phasmatodea): Absolute Configuration and Effects on Ants and Mosquitoes (2012) (9)
Stereochemistry of the reactions of pinacol allylboronate with two α,β-dialkoxyaldehydes (1985) (8)
A Highly Stereoselective Synthesis of 2-Deoxy-β-glycosides Using 2-Deoxy-2-iodo-glucopyranosyl Acetate Donors. (1999) (8)
Structure Based Design of CYP51 Inhibitors. (2016) (8)
Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors. (2011) (8)
Quantum-mechanical study of 10-R-9-borabicyclo[3.3.2]decane alkene hydroboration. (2009) (8)
Generation of Stereochemically Defined Tetrasubstituted Enolborinates by 1,4‐Hydroboration of α,β‐Unsaturated Morpholine Carboxamides with (Diisopinocampheyl)borane. (2014) (8)
Campaign to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR) (2011) (8)
Enantioselective synthesis of the top half of chlorothricolide (1992) (8)
Enantioselective synthesis of (-)-basiliskamide A. (2012) (8)
ML302, a Novel Beta-lactamase (BLA) Inhibitor (2014) (7)
Stereoselective syntheses of substituted methyl (Z,E,E)-deca-2,7.9-trienoates and substituted methyl (Z,E,E)-undeca-2,8,10-trienoates (1980) (7)
Discovery of 2-arylquinazoline derivatives as a new class of ASK1 inhibitors. (2017) (7)
GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation (2015) (7)
Targeting Casein Kinase 1 Delta Sensitizes Pancreatic and Bladder Cancer Cells to Gemcitabine Treatment by Upregulating Deoxycytidine Kinase (2020) (7)
Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma–Induced Osteolysis and Reduces Overall Survival (2021) (7)
Campaign to Identify Agonists of Transient Receptor Potential Channels 3 and 2 (TRPML3 & TRPML2) (2011) (7)
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors (2020) (7)
Synthesis of a bicyclic precursor to verrucarol: application of a trimethylsilyl-controlled Diels-Alder reaction and Wagner-Meerwein rearrangement sequence (1981) (7)
Stereochemically divergent pathways for the allylation and crotylation reactions of anti- and syn-β-hydroxy-α-methyl aldehydes with allyl- and crotyltrifluorosilanes (1999) (6)
Synthesis of 4.beta.-acetoxyscirpene-3.alpha.,15-diol (1985) (6)
HTS Assay for Discovery of Novel Metallo-Beta-lactamase (MBL) Inhibitors (2011) (6)
Synthesis of the C(18)-C(26) segment of superstolide A (2002) (6)
(1'S, 2'S)-METHYL-30,40-(1', 2' -DIMETHOXYCYCLOHEXANE-1', 2'-DIYL)-ALPHA -D-MANNOPYRANOSIDE : (ALPHA -D-MANNOPYRANOSIDE, METHYL 3,4-O-(1,2-DIMETHOXY-1 ,2 -CYCLOHEXANEDIYL)-, 3S(S)-) (1998) (6)
Towards the synthesis of streptovaricin D: Synthesis of fully elaborated aromatic precursors and coupling with ansa chain fragments (1993) (6)
Stereoselective synthesis of the disaccharide unit of incednine. (2013) (6)
Stereochemical and Synthetic Studies of the Intramolecular Diels-Alder Reaction (1990) (6)
TRICHOTHECENE METABOLISM STUDIES: ISOLATION AND STRUCTURE DETERMINATION OF 15-ACETYL-3α-(1′β-D-GLUCOPYRANOSIDURONYL)SCIRPEN-3,4β,15-TRIOL (1985) (6)
Identification of Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry (2011) (5)
Broadening the Existing Intergenerational Structure of Scholarly Development in Chemistry (2004) (5)
ML346: A Novel Modulator of Proteostasis for Protein Conformational Diseases (2013) (5)
9‐Borabicyclo[3.3.1]nonane Dimer (2004) (5)
Design and synthesis of dipeptidyl alpha',beta'-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain. (1998) (5)
Stereoselective Synthesis of 2-Deoxy-β-galactosides via 2-Deoxy-2-bromo- and 2-Deoxy-2-iodo-galactopyranosyl Donors. (2003) (5)
Synthesis of highly functionalized naphthoate precursors to damavaricin D Observation of kinetically stable benzocyclohexadienones in the bromination reactions of highly functionalized β-naphthol derivatives (2001) (5)
SYNTHESIS OF (+)-B-ALLYLDIISOPINOCAMPHEYLBORANE AND ITS REACTION WITH ALDEHYDES. (2012) (5)
Tris(dimethylamino)sulfonium Difluorotrimethylsilicate, a Mild Reagent for the Removal of Silicon Protecting Groups. (1999) (5)
A Publication of Reliable Methods for the Preparation of Organic Compounds (2017) (4)
Identification of Selective Agonists of the Transient Receptor Potential Channels 3 (TRPML3) (2013) (4)
Chlorotris(triphenylphosphine)rhodium(I) (Wilkinson's catalyst) (2009) (4)
A New Synthesis of Peptidyl Epoxysuccinates for Probing Cysteine Protease-Inhibitor P3/S3 Binding Interactions (1999) (4)
Studies on the Synthesis of Kijanolide: Synthesis of an Advanced Seco-acid Intermediate (2002) (4)
Applications of chiral allylmetallating agents toward the synthesis of oxygen heterocyles. (2008) (4)
Synthesis of Aureolic Acid Antibiotics: Highly Stereoselective Synthesis of Aryl 2‐Deoxy‐β‐glycosides via the Mitsunobu Reaction and Synthesis of the Olivomycin A‐B Disaccharide. (2010) (3)
Concerning the Origin of the High β‐Selectivity of Glycosidation Reactions of 2‐Deoxy‐2‐iodo‐glucopyranosyl Trichloroacetimidates. (2003) (3)
A Highly Stereoselective Synthesis of Aryl 2-Deoxy-β-glycosides via the Mitsunobu Reaction. (1992) (3)
The Origin of Diastereofacial Control in Allylboration Reactions Using Tartrate Ester Derived Allylboronates: Attractive Interactions between the Lewis Acids Coordinated Aldehyde Carbonyl Group and an Ester Carbonyl Oxygen [J. Am. Chem. Soc.2002,124, 10692−10697]. (2003) (3)
Fluorometric High-Throughput Screening Assay for Secreted Phospholipases A2 Using Phospholipid Vesicles (2016) (3)
Synthesis of Structurally Simplified Aureolic Acid Aglycone-C-D-E Trisaccharide Analogues (2002) (3)
Enantioselective Total Synthesis of (‐)‐Chlorothricolide (XIV). (1994) (3)
A Formal Total Synthesis of (+)-Tetronolide, the Aglycon of the Tetrocarcins: Enantio- and Diastereoselective Syntheses of the Octahydronaphthalene (Bottom-Half) and Spirotetronate (Top-Half) Fragments. (1998) (3)
An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation. (2021) (3)
Rhodium(II) carboxylates (2017) (3)
Exploiting the co-reliance of tumours upon transport of amino acids and lactate: Gln and Tyr conjugates of MCT1 inhibitors. (2016) (3)
Acyclic Diastereoselective Synthesis Using Tartrate Ester Modified Crotylboronates. Double Asymmetric Reactions with α-Methyl Chiral Aldehydes and Synthesis of the C(19)-C(29) Segment of Rifamycin S. (1990) (3)
Michael Addition Reactions (2009) (2)
Stereochemistry of the Epoxidations of Acyclic Allylic Amides. Applications toward the Synthesis of 2,3,6-Trideoxy-3-aminohexoses. (1988) (2)
Asymmetric Allylboration of Diene Aldehyde Fe(CO)3 Derivatives: Efficient Kinetic Resolution of Racemic Complexes and the Highly Enantiotopic Group and Face Selective Allylboration of a meso Substrate. (1991) (2)
Identification of a novel selective inverse agonist probe and analogs for the Retinoic acid receptor-related Orphan Receptor Gamma (RORγ) (2013) (2)
d Is an APC/C Cdh1 Substrate that Regulates Cerebellar Granule Cell Neurogenesis (2015) (2)
Highly Stereoselective Synthesis of α-L-Olivomycosides via Trimethylsilyl Triflate Mediated Glycosidations of 1-O-Acetyl-4-O- isobutyryl-2,6-dideoxy-2-iodo-3-C-methyl-α-L-mannopyranose. (2010) (2)
Studies on the Synthesis of Nargenicin A1: Highly Stereoselective Synthesis of the Complete Carbon Framework via the Transannular Diels‐ Alder Reaction of an 18‐Membered Macrolide. (1996) (2)
Molecular Modeling of ABHD5 Structure and Ligand Recognition (2022) (2)
Chiral Brønsted Acid Catalyzed Enantioselective Synthesis of anti-Homopropargyl Alcohols via Kinetic Resolution-Aldehyde Allenylboration Using Racemic Allenylboronates. (2013) (2)
2‐Deoxy‐2‐iodo‐ and 2‐Deoxy‐2‐bromo‐α‐glucopyranosyl Trichloroacetimidates: Highly Reactive and Stereoselective Donors for the Synthesis of 2‐Deoxy‐β‐glycosides. (1999) (2)
N,N′-Dibenzyl-N,N′-ethylenetartramide: A Rationally Designed Chiral Auxiliary for the Allylboration Reaction. (1988) (2)
Concerning the Syntheses of the Elusive anti,anti-Dipropionate Stereotriad via the Crotylation of β-Hydroxy α-Methyl Aldehydes with (Z)-Crotyltrifluorosilane. Application to the Synthesis of the C7—C16 Segment of Zincophorin. (1998) (2)
Total Synthesis of (+)-Damavaricin D. (1998) (2)
A Stereochemically General Synthesis of 2‐Deoxyhexoses via the Asymmetric Allylboration of 2,3‐Epoxy Aldehydes. (1991) (2)
Studies Toward the Total Synthesis of Angelmicin B (Hibarimicin B) (II): Synthesis of a Model CD—D′ Arylnaphthoquinone (I). (2005) (2)
Diastereo- and Enantioselective Aldehyde Addition Reactions of 2-Allyl-1,3,2-dioxaborolane-4,5-dicarboxylic Esters, a Useful Class of Tartrate Ester Modified Allylboronates. (1986) (2)
Total Synthesis of Olivomycin A. (1999) (2)
Design and Synthesis of Dipeptidyl α′,β′-Epoxy Ketones, Potent Irreversible Inhibitors of the Cysteine Protease Cruzain. (1999) (2)
Discovery and optimization of a series of sulfonamide inverse agonists for the retinoic acid receptor-related receptor-α. (2019) (2)
Applications of Allylboronates in the Synthesis of Carbohydrates and Polyhydroxylated Natural Products (1990) (2)
Enantio- and diastereoselective synthesis of syn-β-hydroxy-α-alkenyl carboxamides via reductive aldol reactions of morpholine 4-methyl-2,3-pentadienoic carboxamide with diisopinocampheylborane (2015) (2)
Enantioselective Synthesis of 2-Methyl-1,2-syn- and 2-Methyl-1,2-anti-3-butenediols via Allene Hydroboration—Aldehyde Allylboration Reaction Sequences. (2010) (2)
Synthesis of the C(29)—C(45) Bis-pyran Subunit (E—F) of Spongistatin 1 (Altohyrtin A). (2001) (1)
Enantio‐ and Diastereoselective Synthesis of (E)‐1,5‐syn‐Diols: Application to the Synthesis of the C(23)—C(40) Fragment of Tetrafibricin. (2011) (1)
Studies on the Synthesis of 2,6-Disubstituted Dihydropyrans: Intervention of Oxonia-Cope Rearrangements in the Lewis Acid Mediated Cyclodehydrative Reactions of Aldehydes and β-Hydroxyallylsilanes. (2001) (1)
ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450 Enzyme CYP3A4 (2014) (1)
Diastereoselective Synthesis of N-Benzoyl Mycalamine, the Fully Elaborated Trioxadecalin Nucleus of Mycalamide A. Control of the Key N- Acyl Aminal Stereocenter via Carbamate Acylation. (1995) (1)
Enantioconvergent Hydroboration of a Racemic Allene: Enantioselective Synthesis of (E)‐δ‐Stannyl‐anti‐homoallylic Alcohols via Aldehyde Crotylboration. (2011) (1)
Organic Reactions. Volume 29 (1984) (1)
Stereoselective Synthesis of γ-Substituted (Z)-Allylic Boranes via Kinetically Controlled Hydroboration of Allenes with 10-TMS-9-Borabicyclo[3.3.2]decane. (2010) (1)
Studies on the Synthesis of the Mycalamides: Stereocontrolled Synthesis of a Model N‐Glycosylpederamide (VIII) via a Stereoselective Aldol Reaction. (1998) (1)
STEREOCHEMISTRY OF CROTYLBORONATE ADDITIONS TO α,β-DIALKOXY ALDEHYDES (1985) (1)
Stereoselective Synthesis of 2‐Deoxy‐β‐glycosides from Glycal Precursors. Part 2. Stereochemistry of Glycosidation Reactions of 2‐ Thiophenyl‐ and 2‐Selenophenyl‐α‐D‐gluco‐pyranosyl Donors. (1997) (1)
Chloromethyl phenyl sulfide (2006) (1)
Synthesis of Tedanolide: Synthesis of the C5—C21 Segment via a Highly Stereoselective Fragment Assembly Aldol Reaction of a Chiral β,γ‐Unsaturated Methyl Ketone. (1999) (1)
Enantioselective Reductive Syn-Aldol Reactions of 4-Acryloylmorpholine: Preparation of (2R, 3S)-3-Hydroxy-2-methyl-1-morpholino-5-phenylpentan-1-one (2015) (1)
Highly (E)-Selective BF3·Et2O-Promoted Allylboration of Chiral Nonracemic α-Substituted Allylboronates and Analysis of the Origin of Stereocontrol. (2010) (1)
Hydroxylamine-O-sulfonic acid (2006) (1)
Classification of Mushroom Substrate Odors Using a Portable Electronic Nose and Neural Networks (2003) (1)
Methyl iodide. (1986) (1)
Enantio‐ and Diastereoselective Synthesis of Cyclic β‐Hydroxy Allylsilanes via Sequential Aldehyde γ‐Silylallylboration and Ring‐Closing Metathesis Reactions. (2003) (1)
Copper(I) cyanide (2017) (1)
A Highly Diastereo- and Enantioselective Synthesis of the Top Half of Kijanolide. (1993) (1)
Therapeutics , Targets , and Chemical Biology Blocking Lactate Export by Inhibiting the Myc Target MCT 1 Disables Glycolysis and Glutathione Synthesis (2014) (1)
Studies on the Synthesis of Chlorothricolide: Diastereo- and Enantioselective Syntheses of Model Top-Half Spirotetronate Units. (1998) (1)
Studies on the synthesis of tedanolide: synthesis of the C(5)-C(21) segment via a highly stereoselective fragment assembly aldol reaction of a chiral beta,gamma-unsaturated methyl ketone. (1999) (1)
2‐Deoxy‐2‐iodo‐α‐mannopyranosyl and ‐talopyranosyl Acetates: Highly Stereoselective Glycosyl Donors for the Synthesis of 2‐Deoxy‐α‐glycosides. (1999) (1)
t‐Butoxybis(dimethylamino)methane [Brederick's reagent] (2006) (1)
Highly Stereoselective Substitution Reactions of Functionalized η4‐ (3(E),5(E)‐Heptadien‐2‐ol)iron Tricarbonyl Complexes. (1995) (1)
Application of η4-Diene Iron Tricarbonyl Complexes in Acyclic Stereocontrol: Asymmetric Synthesis of the as-Indacene Unit (XII) of Ikarugamycin (XIII) (a Formal Total Synthesis). (1994) (1)
The Vinylogous Intramolecular Morita—Baylis—Hillman Reaction: Synthesis of Functionalized Cyclopentenes and Cyclohexenes with Trialkylphosphines as Nucleophilic Catalysts. (2002) (1)
N‐Chlorosuccinimide (NCS) (2010) (1)
4,5-Diisopropyl-B-((E)-((3′-menthofuryl)dimethylsilyl)allyl)-1,3,2- dioxaborolane, an Improved Chiral Reagent for the anti-α- Hydroxyallylation of Aldehydes: Application to the Enantioselective Synthesis of (-)-Swainsonine. (1997) (1)
Cathepsins X and Β Display Distinct Activity Profiles That Can Be Exploited for Inhibitor Design (2001) (1)
Reasons for Cancellation and No-Show in an Outpatient Palliative Care Clinic (TH308D) (2018) (1)
REGIOSELECTIVITY OF THE REACTIONS OF TRIALKYLALUMINUM REAGENTS WITH 2,3-EPOXY ALCOHOLS: APPLICATION TO THE SYNTHESIS OF α-CHIRAL ALDEHYDES (1983) (1)
Synthesis of (-)-Spinosyn A (2008) (1)
Chemical Assembly of Antibody-Drug Conjugates (2017) (1)
ML322, A Small Molecule Inhibitor of Dimerization of the Core Protein of Hepatitis C Virus (HCV) (2014) (1)
Allylboronates in Organic Synthesis: Design of an Improved Chiral Auxiliary and Synthesis of the Trioxadecalin Nucleus of Mycalamides A and B (1995) (1)
STEREOSELECTIVE SYNTHESES OF SUBSTITUTED METHYL (Z,E,E)-DECA-2,7,9-TRIENOATES AND SUBSTITUTED METHYL (Z,E,E)-UNDECA-2,8,10-TRIENOATES (1980) (1)
Toward the Synthesis of Mycalamides A, B, and Onnamide A: A Highly Stereoselective Synthesis of the Trioxadecalin Ring System. (1994) (1)
Stereochemistry of the Allylation and Crotylation Reactions of α‐Methyl‐β‐hydroxy Aldehydes with Allyl‐ and Crotyltrifluorosilanes. Synthesis of anti,anti‐Dipropionate Stereotriads and Stereodivergent Pathways for the Reactions with 2,3‐anti‐ and 2,3‐syn‐α‐Methyl‐β‐hydroxy Aldehydes. (2003) (1)
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation. (2022) (1)
ChemInform Abstract: Highly Diastereoselective Synthesis of Propargylic 1,2-anti-Diol Derivatives Using α-Alkoxypropargylstannanes. (2002) (1)
Copper(I) t-Butoxide (2017) (1)
Organophosphorus compounds (incl. RO-P and RN-P) (2009) (1)
Table 2, Summary of Results (2013) (1)
Applications of Tartrate Ester Modified Allylic Boronates in Organic Synthesis: An Efficient, Highly Stereoselective Synthesis of the C(19)-C(29) Segment (X) of Rifamycin S. (1987) (1)
The Aza-Morita–Baylis–Hillman Reaction (2009) (1)
Total Synthesis of Mycalamide A (IX) and 7-epi-Mycalamide A (V). (2000) (1)
N,N-Dimethylformamide (DMF) (2006) (1)
Enantioselective Synthesis of 2-Alkyl-5-methylene-1,3-dioxolan-4-ones and Exo-Selective Diels-Alder Reactions with Cyclopentadiene. (2010) (1)
Highly Selective Lewis Acid Catalyzed Diels-Alder Reactions of Acyclic (Z)-1,3-Dienes. (1997) (1)
Evolution of a Strategy for the Synthesis of Olivomycin a: Development of Methodology for the Diastereo- and Enantioselective Synthesis of Carbohydrates from Acyclic Precursors (1989) (1)
Diphenyl diselenide–Copper(II) acetate (2006) (0)
Triethylammonium formate–Palladium (2006) (0)
Phenyl propargyl selenide (2006) (0)
Tandem Phosphorylsilylation/Ireland–Claisen Rearrangement (2009) (0)
Figure 7, Dose response curves for SR-01000621848 (Probe 1, ML180) and SR-01000001309 (Probe 2, ML179) two LRH-1 modulator probes (2011) (0)
Sodium hydroxide–Potassium carbonate (2006) (0)
Hydrogen chloride, anhydrous (2009) (0)
Boron trifluoride etherate (2017) (0)
Trichothecene Degradation Studies: Synthesis of 12,13-Deoxyanguidine (I) and 12,13-Deoxyverrucarol (II). (1986) (0)
Figure 7, Mass spectrum, calc for M+1: 273.08, found 273.10 (2013) (0)
[Table], Metallo-beta Lactamase Inhibitor SAR Table: Rhodanine Scaffold (2014) (0)
Boronic acid resins (2006) (0)
Lewis Acid Catalyzed Intramolecular Diels—Alder Reactions of Acyclic (Z)-Substituted 1,3-Dienes. (2001) (0)
Mercury(II) nitrite (2006) (0)
Table 2, Assays for the current probe discovery effort (ML302) (2014) (0)
3,3-Diethoxy-1-propene (Acrolein diethyl acetal) (2006) (0)
(S)‐p‐Tolyl p‐tolylthiomethyl sulfoxide1 (2006) (0)
Studies on the Synthesis of Nargenicin A1. An Example of an Intramolecular Diels-Alder Reaction that Proceeds with a Boat-Like Conformation of the Connecting Chain. (1987) (0)
Bromomethyl phenyl sulfoxide (2006) (0)
Table 10, TCID50 Results (see AID 624575) (2014) (0)
Synthesis of Highly Functionalized Naphthoate Precursors to Damavaricin D — Observation of Kinetically Stable Benzocyclohexadienones in the Bromination Reactions of Highly Functionalized β-Naphthol Derivatives. (2002) (0)
Table 7, Secondary assay results (Strosberg lab) (2014) (0)
A STEREORATIONAL TOTAL SYNTHESIS OF (-)-PTILOCAULIN (1985) (0)
Figure 7, Dose response curves for Probe ML322 in the Alphascreen (A), QPCR T1/T2 (B), and TCID50 assays (C) (2014) (0)
Hydrogen peroxide–Pyridinium polyhydrogen fluoride (2006) (0)
N,N′‐Bis(2,2,2‐trifluoroethyl)‐N,N′‐ethylenetartramide: An Improved Chiral Auxiliary for the Asymmetric Allylboration Reaction. (1995) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor ( R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-( 4-chlorophenyl)piperazin-1-yl)-2-fluorobenzamide. (2014) (0)
Figure 5, Dose response curves for ML302 (2014) (0)
2,2′‐Dihydroxy‐1,1′‐binaphthyl‐Lithium aluminum hydride (2006) (0)
Sodium amide–Sodium t‐butoxide (2006) (0)
Diastereoselective Synthesis of the cis-Octahydronaphthalene Nucleus of Superstolides A and B. (2010) (0)
Figure 12, Probe ML346 (compound F1) reduces aggregation/toxicity in C. elegans models of diseases associated with polyQ expansions (2013) (0)
Figure 9, Stability of Probe ML346 (2013) (0)
Diethyl 1‐trimethylsilyloxyethylphosphonate (2006) (0)
Formaldehyde–Diisopropylamine–Copper(I) bromide (2006) (0)
B‐Butyl‐9‐borabicyclo[3.3.1]nonane 1 (2006) (0)
Second Generation Synthesis of the Quartromicin Spirotetronic Acid Subunits via a Claisen Rearrangement‐Intramolecular Aldol Sequence. (1998) (0)
Diastereoselective Synthesis of the Top Half of Kijanolide. (1990) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-2-fluoro-4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)benzamide (2014) (0)
Identification of a Synthetic Agonist for the Orphan Nuclear Receptors ROR α and ROR γ , SR1078 (2011) (0)
Palladium(II) acetate‐Tri‐o‐tolylphosphine (2006) (0)
[Table], RORα and RORα/γ Inverse Agonist Probes (2011) (0)
Ketene diethyl acetal (2006) (0)
2,4,6‐Trichlorobenzoyl chloride (2006) (0)
Colonic Model Inhibitor of Amebic Invasion in a Human Cysteine Proteinase 1 To Identify a Potent Entamoeba histolytica Use of Recombinant (2013) (0)
[Table], CID, SID and ML# of the probe and five related analog samples submitted to the SMR collection (2011) (0)
Ethyl (E)‐3‐methylthio‐2‐methyl‐2‐butenoate 1 (2006) (0)
[Table, Probe chemical structure including stereochemistry. Separation of diastereomers (if necessary)]. (2011) (0)
2-Deoxy-2-iodo-beta-glucopyranosyl fluorides: mild and highly stereoselective glycosyl donors for the synthesis of 2-deoxy-beta-glycosides from beta-hydroxy ketones. (2003) (0)
Concerning the Diastereofacial Selectivity of Aldol Reactions of Chiral Methyl Ketone Enolates: Evidence for Remote Chelation in the Bafilomycin Aldol Reaction. (1994) (0)
[Table, Antibiotic Synergy Assays]. (2011) (0)
Figure 4, Modulation of endogenous G6Pase by new RORα inverse agonist probe (CID 2360837; ML176) in HepG2 cells (2013) (0)
Applications of Tricoordinated Phosphorus Compounds in Organocatalysis (2011) (0)
1‐Methoxy‐1,3‐bis(trimethylsilyloxy)‐1,3‐butadiene 1 (2006) (0)
1,2‐Dihydro‐4,6‐dimethyl‐2‐thioxo‐3‐pyridinecarbonitrile 1 (2006) (0)
Dimethyl sulfoxide–Chlorotrimethylsilane (2006) (0)
Stereoselective Synthesis of the Octahydronaphthalene Unit of Integramycin (I) via an Intramolecular Diels—Alder Reaction. (2005) (0)
Scheme 2, (a) PMB-Br, K2CO3, DMAC; (b) 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, Pd(Ph3P)4, K2CO3, THF; (c) TFA; (d) RCNO, toluene (2014) (0)
Lithium diisopropylamide (LDA) (2017) (0)
Dimethylformamide diethyl acetal (2006) (0)
CRYSTAL STRUCTURE ANALYSIS OF CRYZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (IV) (2000) (0)
Bis(triphenylphosphine)copper(I) borohydride (2006) (0)
Dimethyl 1,3‐acetonedicarboxylate (2006) (0)
Table 3, Wee1 Degradation Inhibitor Probes and Prior Art (2013) (0)
((Z)-γ-((Diisopropylidene-α-D-mannopyranosyl)oxy)allyl)- tributylstannane: A New Chiral Reagent for the Asymmetric α- Hydroxyallylation of Aldehydes. (1995) (0)
4-Phenyl-1,2,4-triazoline-3,5-dione (PTAD) (2010) (0)
Table 2, Solubility at 100 μM; 1% DMSO (2013) (0)
[Table, Solubility and Stability data for the new analogs]. (2011) (0)
Figure 5, Flow chart of HTS screening for NOX1 inhibitors (2011) (0)
Diisopropyl Tartrate Modified (E)‐γ‐((Menthofuryl)dimethylsilyl) allylboronate, an Improved Chiral Reagent for the anti α‐ Hydroxyallylation of Aldehydes. Application to the Enantioselective Synthesis of (‐)‐Swainsonine. (1995) (0)
[Table, Comparison to existing art and how the new probe is an improvement]. (2011) (0)
Studies on the Synthesis of Apoptolidin A (I). Part 1. Synthesis of the C(1)—C(11) Fragment. (2008) (0)
Studies on the Synthesis of Apoptolidin A. Part 2. Synthesis of the Disaccaride Unit. (2008) (0)
Towards an Effective Neuroprotective Strategy for Glaucoma: Identification of Protein Kinase Inhibitors That Promote RGC Survival and Neurite Outgrowth (2010) (0)
t‐Butyl Hydroperoxide (2013) (0)
Copper(0)‐Isonitrile complexes (2006) (0)
3‐Nitro‐2‐pyridinesulfenyl chloride (2006) (0)
Lithium–Ethylenediamine (LEDA) (2006) (0)
[4+2]-Cycloaddition Reactions (2009) (0)
Hydrogen Peroxide–N,N′-Carbonyldiimidazole (2006) (0)
Benzyl(triethyl)ammonium permanganate (2006) (0)
Figure 10, One Step Synthesis of ML346 (CID 767276) (2013) (0)
Dimethyl sulfoxide–Trichloroacetic anhydride (2006) (0)
Crystal structure of Casein kinase 1 delta (CK1 delta) complexed with SR3029 inhibitor (2020) (0)
2‐Tetrahydrothienyl diphenylacetate 1 (2006) (0)
Figure 1, Probe Stability (2011) (0)
t‐Butyl hydroperoxide–Selenium dioxide (2006) (0)
A Highly Stereoselective Synthesis of (+)-Olivin, the Aglycon of Olivomycin A. (1989) (0)
2,2,2‐Trichloroethyl (E)‐1,3‐butadiene‐1‐carbamate (2006) (0)
Nickel(II) bromide—Zinc (2006) (0)
Figure 1, Alphascreen Technology (2014) (0)
Sodium sulfide–Thiophenol (2006) (0)
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates (2017) (0)
Enantioselective Synthesis of (E)‐δ‐Stannyl Homoallylic Alcohols via Aldehyde Allylboration Using α‐Stannylallylboranes Generated by Allene Hydroboration Followed by a Highly Diastereoselective 1,3‐Boratropic Shift. (2010) (0)
Dimethylformamide–Oxalyl chloride (2006) (0)
Studies on the Synthesis of Kijanolide: Synthesis of the 2-Acyl Spiro Tetronate and Investigations Concerning the Coupling of the Tope and Bottom Half Fragments. (1993) (0)
Methyl fluorosulfonate (Magic Methyll) (2006) (0)
Manganese(II) Chloride (2017) (0)
Stereochemistry of the allylation and crotylation reactions of alpha-methyl-beta-hydroxy aldehydes with allyl- and crotyltrifluorosilanes. Synthesis of anti,anti-dipropionate stereotriads and stereodivergent pathways for the reactions with 2,3-anti- and 2,3-syn-alpha-methyl-beta-hydroxy aldehydes. (2003) (0)
Potassium hexamethyldisilazide (KHMDS) (2006) (0)
Lithium aluminum hydride (2017) (0)
Table 4, Further comparison of ROR Probes (2013) (0)
Bis(diethylaluminum) sulfate (2006) (0)
Mercury(II) Oxide–Tetrafluoroboric Acid (2006) (0)
Table 4, Comparison of ML302 to existing Art (2014) (0)
Asymmetric Synthesis Using Diisopropyl Tartrate Modified (E)‐ and (Z)‐Crotylboronates: Preparation of the Chiral Crotylboronates and Reactions with Achiral Aldehydes. (1990) (0)
Stereoselective Synthesis of 2‐Deoxy‐β‐glycosides from Glycal Precursors. Part 1. Stereochemistry of the Reactions of D‐Glucal Derivatives with Phenylsulfenyl Chloride and Phenylselenenyl Chloride. (1997) (0)
hydrogen fluoride (2020) (0)
Ozone–Silica gel (2006) (0)
Table 12, Comparison of the prior art with HCV Core probe ML322 (2014) (0)
Enantioselective Total Synthesis of (-)-Chlorothricolide via the Tandem Inter- and Intramolecular Diels—Alder Reaction of a Hexaenoate Intermediate. (1998) (0)
4‐Methoxy‐6‐methyl‐2‐pyranone 1 (2006) (0)
Figure 2, LRMS of probe ML178 (2011) (0)
Development of a putative Zn2+-chelating but highly selective MMP-13 inhibitor. (2022) (0)
3,5‐Dinitroperoxybenzoic acid (2006) (0)
Synthesis and Diels-Alder Reactions of 2-Alkyl-5-methylene-1,3-dioxolan-4-ones (Va), (Vb) and 2-Alkyl-3-acyl-5-methylene-1,3-oxazolidin-4-ones (Vc): Highly Exo and Diastereoface Selective Chiral Ketene Equivalents. (1990) (0)
Abstract B004: A combination of two chemically distinct inhibitors of class I HDACs is highly effective to suppress AR signaling and in vivo growth of prostate cancer xenograft (2018) (0)
Use of Metal Carbonyl Complexes to Achieve High Enantioselectivity in the Asymmetric Allylboration of Unsaturated Aldehydes. (1990) (0)
Methyl cyclobutenecarboxylate 1 (2006) (0)
Structure of WRR-483 bound to cruzain (2013) (0)
Development of a Zn 2+-Chelating But Highly Selective Matrix Metalloproteinase 13 Inhibitor (2022) (0)
Iodomethyl methyl ether (2006) (0)
Binding mode, selectivity and potency of N-indolyl-oxopyridinyl-4- amino-propanyl-based inhibitors targeting Trypanosoma cruzi CYP51 (2014) (0)
[(E)‐γ‐(Dimethylphenylsilyl)allyl]diisopinocampheylborane: A Highly Enantioselective Reagent for the Synthesis of anti‐β‐Hydroxyallylsilanes. (2001) (0)
t‐Butyl Lithioacetate (2006) (0)
1‐Amino‐2‐Methoxymethyl‐1‐Pyrrolidine (RAMP and SAMP) 1 (2006) (0)
Lead tetraacetate (LTA) (2006) (0)
Phenyl trimethylsilyl selenide (2006) (0)
A Three‐Component Coupling Strategy for Tetrahydrofuran Synthesis: Application of the Diisopropyl Tartrate, Modified (E)‐γ‐(Dimethylphenylsilyl)allylboronate as an α,γ‐Allyl Dianion Equivalent. (2000) (0)
Isomerization of Activated Alkynes to Dienes (2009) (0)
Stereochemically Divergent Pathways for the Allylation and Crotylation Reactions of anti‐ and syn‐β‐Hydroxy‐α‐methyl Aldehydes with Allyl‐ and Crotyltrifluorosilanes. (1999) (0)
SAR Table 3, Additional synthesized and purchased analogs (2011) (0)
Diethyl azodicarboxylate (DEAD) (2006) (0)
Figure 5, Proposed Mechanism of action of probe ML176 (2013) (0)
Effect of Dienophile Activating Group on the Stereoselectivity of the Intramolecular Diels-Alder Reaction. (1987) (0)
An Improved Synthesis of the (E,Z)‐Dienoate Precursor of (+)‐Damavaricin D via a Vinylogous Horner—Wadsworth—Emmons Reaction. (1999) (0)
Abstract B064: Therapeutic potential of CK1 delta inhibition in pancreatic and bladder cancer (2018) (0)
Table 1, Assays from the HTS campaign and prior probe discovery effort (ML121) (2014) (0)
Morpholine–Camphoric acid (2006) (0)
[Table], Table of Assay Rationale and Screening Statistics (2011) (0)
TRPML3/2 Agonist SAR Table 1, Secondary Arylsulfonamides Scaffold (2011) (0)
N‐Ethyl(diethylphosphono)methylketenimine 1 (2006) (0)
Enantio- and diastereoselective synthesis of syn-beta-hydroxyallylsilanes via a chiral (Z)-gamma-silylallylboronate. (2007) (0)
Diastereoselective Synthesis of the trans-anti-cis-Decahydro-as- indacene Ring System via the Transannular Diels-Alder Reaction of a Functionalized (E,E,E)-Cyclododeca-1,6,8-triene. (1997) (0)
Management of the emergency scene. (1980) (0)
Palladium(II) acetate‐Triphenylphosphine (2006) (0)
Scheme 1, Reagents and conditions: (a) DIPEA, iPrOH, 90 °C, 2h (2011) (0)
A New Synthesis of Peptidyl Epoxysuccinates for Probing Cysteine Protease-Inhibitor P3/S3 Binding Interactions. (1999) (0)
2‐Hydroperoxyhexafluoro‐2‐propanol 1 (2006) (0)
Sodium sulfide-Sulfur (Sodium polysulfide) (2006) (0)
Figure 2, Probe ML346 (“F1”) induces Hsp70 mRNA expression (2013) (0)
Hexamethylphosphorous triamide–Iodine (2006) (0)
Osmium tetroxide–N-Methylmorpholine N-oxide (2006) (0)
Sodium hydride‐Butyllithium (2006) (0)
Figure 8, HPLC spectrum; purity >95% (2013) (0)
Aluminum chloride–Potassium chloride–Sodium chloride (2006) (0)
Total Synthesis of (‐)‐Bafilomycin A1 (I): Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions. (1999) (0)
Phase‐transfer catalysts (2011) (0)
Dimethyl sulfide–Trifluoroacetic anhydride (2006) (0)
Studies on the Total Synthesis of Formamicin: Synthesis of the C(1)—C(11) Fragment. (2001) (0)
Table 5, Ki values demonstrating ML302 is a mixed mode uncompetitive and non-competitive inhibitor (2014) (0)
Nucleophilic Interception at the α-Position (2009) (0)
Abstract LB-248: Chemically distinct class I HDAC inhibitors synergize to inhibit global lipid metabolism in cancer (2018) (0)
N‐Morpholinomethyldiphenylphosphine oxide 1 (2006) (0)
Table 5, The top Round 0 analog results (2014) (0)
Intramolecular Morita–Baylis–Hillman Allylic Alkylation (2009) (0)
Pentane-1,5-di(magnesium bromide) (2006) (0)
Table 4, Most potent scaffolds from the HTS campaign (2014) (0)
(2-Carboxy-2-propenyl)triphenylphosphonium bromide (2006) (0)
Synthesis of the C11—C29 Fragment (I) of Amphidinolide F (II). (2005) (0)
Diisobutylaluminum Hydride, (DIBAL‐H) (2013) (0)
2,3‐O‐Isopropylidene‐2,3‐dihydroxy‐1,4‐bis(diphenylphosphino)butane (DIOP) (2006) (0)
Hexamethylphosphoric triamide (HMPT) (2006) (0)
Glyoxylic acid dithioethyl acetal (2006) (0)
Probing the Lewis Acid‐Catalyzed Intramolecular Diels—Alder Cyclizations of Allylic Alkoxy‐Substituted (Z)‐1,3‐Dienes. (2004) (0)
Abstract 3051: Targeting cdk12/13 re-sensitizes trastuzumab resistant her2+ breast cancers (2019) (0)
Table 1, Assay Summaries (2013) (0)
Table 3, SAR of Probe Compounds (2011) (0)
Phosphoryl chloride (Phosphorus oxychloride) (2009) (0)
Table 1, Related PubChem Bioassays (2013) (0)
Studies of Fragment Assembly Aldol Reactions of Chiral Aldehydes and Chiral Methyl Ketones: Stereoselective Synthesis of the C(13)—C(25) Segment of Scytophycin C. (1999) (0)
Scheme 1, Synthesis of ML368 (SR-9186) (2014) (0)
Sodium hydrogen sulfide (2013) (0)
Phthalimide-N-sulfenyl chloride (2006) (0)
Systems analysis of intracellular pH vulnerabilities for cancer therapy (2018) (0)
O-Ethyl S-cyanomethyl dithiocarbonate (2006) (0)
A CK1δ/CK1ε-to-Wnt/β-Catenin Circuit Is a Therapeutic Vulnerability in Primary and Drug Resistant Multiple Myeloma (2016) (0)
Oxalyl chloride–Sodium iodide (2006) (0)
[Table], Comparative Activity Table: Probe and Prior Art Compounds (2011) (0)
Potassium hydroxide–Dimethyl sulfoxide (2006) (0)
Carbon disulfide–Methyl iodide (2006) (0)
Tellurium(IV) chloride (2006) (0)
Origin of Thermodynamic versus Kinetic Control of Allene Hydroboration with 9-Borabicyclo[3.3.1]nonane and 10-R-9-Borabicyclo[3.3.2]decane (2010) (0)
Dichloromethyl methyl sulfide (2006) (0)
Total Synthesis of (-)-Spinosyn A (Ib): Examination of Structural Features that Govern the Stereoselectivity of the Key Transannular Diels—Alder Reaction. (2008) (0)
Hydridotris(triisopropylphosphine)rhodium(I) (2009) (0)
Bis(tributyltin) oxide (2006) (0)
Potassium 3-aminopropylamide (KAPA) (2006) (0)
Iodoacetoxylation of Glycals Using Cerium(IV) Ammonium Nitrate, Sodium Iodide, and Acetic Acid: Stereoselective Synthesis of 2‐Deoxy‐2‐iodo‐α‐mannopyranosyl Acetates. (2010) (0)
Simmons‐Smith reagent (2006) (0)
Table 1, Substituted isoxazole carboxamides as potent STAT3 activators (2010) (0)
Synthesis of the C(3)-C(15) Segment of Rutamycin B via a C(8)-C(9) Fragment Assembly Aldol Reaction: Metal Dependence of the Aldehyde and Enolate Diastereofacial Selectivities. (1995) (0)
Triphenylbismuth carbonate 1 (2006) (0)
Table 1, P450 inhibition of substituted phenyl urea analogs (2014) (0)
p-Nitroperoxybenzoic acid (2006) (0)
Dibenzoyl peroxide–Nickel(II) bromide (2006) (0)
2‐Chloroethyl thiocyanate (2006) (0)
Chloromethyl methyl ether (2009) (0)
Figure 8, Comparison of the structures of the original HTS lead and final Probe ML322 (2014) (0)
N,N-Dimethyl dichlorophosphoramide (2006) (0)
Table 1, HCV Core Inhibitors Project (see also Summary AID 1911) (2014) (0)
Aluminum chloride–Potassium phenoxide (2006) (0)
Small-Molecule Inhibitors of Acetyltransferase p300 Identi ﬁ ed by High-Throughput Screening Are Potent Anticancer Agents (2013) (0)
SAR Table 1, Lead scaffolds from the HTS campaign (2014) (0)
Figure 1, Probe ML346 is not toxic to HeLa cells (2013) (0)
Zinc-Hydrochloric acid-t-Butyl alcohol (2006) (0)
[Table, FACS analysis/G2/M Arrest Assays]. (2011) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor ( R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-( 3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. (2014) (0)
Tetrabutylammonium di‐t‐butylphosphate (2006) (0)
Copper(II) Chloride (2017) (0)
Trimethyl 3‐(phenylseleno)orthopropionate, 1 (2006) (0)
t‐Butyl hydroperoxide–Vanadyl acetylacetonate (2006) (0)
Palladium(II) acetate (2017) (0)
[Table, Chemical optimization of ML125]. (2011) (0)
Dicarbonylcyclopentadienylironmethyldimethylsulfonium tetrafluoroborate 1 (2006) (0)
Sodium borohydride–1,2;5,6‐Di‐O‐isopropylidene‐α‐D‐glucofuranose (2006) (0)
Synthesis of Structurally Simplified Aureolic Acid Aglycone-C—D—E Trisaccharide Analogues. (2002) (0)
Table 4, SAR Table of Phenothiazines (2011) (0)
Enantiodivergent Hydroboration Reactions of a Racemic Allenylsilane with Diisopinocampheylborane and Curtin-Hammett Controlled Double Asymmetric Crotylboration Reactions of (S)-E-α-phenyldimethylsilyl( d diisopinocampheyl)-crotylborane. (2013) (0)
Phosphine-Mediated Reductive Condensation of Acyloxybutynoates (2009) (0)
Figure 5, Summary of profile between FKL-135 and a set of 296 kinases (2013) (0)
Enantioselective Synthesis of the Bottom Half of Chlorothricolide. Part 2. A Comparative Study of Substituent Effects on the Stereoselectivity of the Key Intramolecular Diels-Alder Reaction. (1988) (0)
N-Ethyl-2-pyrrolidone (NEP) (2006) (0)
Figure 6, New probe CID 2360837 (ML176) reduces the hepatic glucose production in animal models (2013) (0)
Table 2, SAR of Probes and Selected Analogs (2011) (0)
4‐Dimethylamino‐3‐butyn‐2‐one 1 (2006) (0)
Silver(I) trifluoromethanesulfonate (triflate) (2010) (0)
Enantioselective Synthesis Using Diisopropyl Tartrate Modified E- (I) and Z-Crotylboronates (II): Reactions with Achiral Aldehydes (III). (1989) (0)
Rhodium oxide‐Platinum oxide (Nishimura catalyst) (2006) (0)
Diethyl phosphorocyanidate (DEPC) (2006) (0)
Enantio- and Diastereoselective Synthesis of syn-β-Hydroxyallylsilanes via a Chiral (Z)-γ-Silylallylboronate. (2008) (0)
Figure 8, ML180 Nuclear Receptor Promiscuity (2011) (0)
Use of Thallium(I) Ethoxide in Suzuki Cross‐Coupling Reactions. (2000) (0)
Asymmetric Construction of (E)-δ-Stannyl HomoallylicAlcohols (2010) (0)
From a chelating, non-selective chemical probe to selective MMP-13 inhibitors for the treatment of osteoarthritis (2018) (0)
Figure 7, Treatment with compound 1 (ML171) significantly blocks ECM degradation in DLD1 cells (2011) (0)
[Table, Kinase profiling]. (2011) (0)
Nucleophilic Addition Reactions at Nonactivated Positions (2009) (0)
Abstract P2-01-05: Targeting of casein kinase 1δ inhibits triple negative breast cancer metastasis (2019) (0)
Stereochemistry of the Reactions of Pinacol Allylboronate with Two α,β-Dialkoxyaldehydes. (1985) (0)
Figure 3, Stability of Probe ML171 in PBS (2011) (0)
Tandem α- or γ-Addition and Michael Addition Reactions (2009) (0)
Synthesis of 4β-Acetoxyscirpene-3α,15-diol. (1986) (0)
Methoxymethyl(diphenyl)phosphine oxide (2006) (0)
Figure 6, Compound 1 (ML171) treatment significantly blocks invadopodia formation in DLD1 cells (2011) (0)
Figure 3, Probe analogs (2014) (0)
Dimethyl N-(p-tosyl)sulfoximine (2006) (0)
HIGHLY STEREOSELECTIVE SYNTHESIS OF 2-DEOXY-BETA-GLYCOSIDES. APPLICATION TO THE TOTAL SYNTHESIS OF LANDOMYSIN A (2002) (0)
Figure 5, Probe ML346 restores proteostasis (2013) (0)
Hydrogen peroxide–Selenium(IV) oxide (2006) (0)
Figure 1, Stability Analysis of ML302 and its HCl salt (2014) (0)
Evolution of a strategy for the synthesis of olivomycin a development of methodology for the diastereoselective and enantioselective synthesis of carbohydrates from acyclic precursors (1988) (0)
SAR Table 2, Probe and lead analogs (2014) (0)
Ion-exchange resins (2006) (0)
Sodium borohydride–Bis(2,4‐pentanedionato)copper (2006) (0)
Chromium(II)-Amine complexes (2006) (0)
Tributylphosphine–Diphenyl disulfide (2006) (0)
Table 2, Probe Properties (2014) (0)
Sodium–Hexamethylphosphoric triamide (2006) (0)
Thexylborane–N,N-Diethylaniline (TBDA) (2006) (0)
Polyphosphate ester (PPE) (2006) (0)
Asymmetric Synthesis of the Hydroxylamino Sugar of Calicheamicin. (1994) (0)
Synthesis of the C(21)—C(26) Fragment (I) of Superstolide A (II): Concerning the Stereochemistry of (E)-Crotylboration Reactions of Alaninal Derivatives. (2003) (0)
Figure 4, Results of a Cell Titer Glo-based cytotoxicity assay (2013) (0)
Figure 4, Selection of SID 49716510 as the starting point for SAR hit optimization (2014) (0)
p‐Nitrobenzene selenocyanate (2006) (0)
Figure 4, Synthesis of Hydrochloride Salt of the Probe (CID 53384679, Compound 3) (2014) (0)
Thallium(III) trifluoroacetate (TTFA) (2006) (0)
Abstract 4718: SR-4370, a potent and selective inhibitor of class I HDACs, suppresses AR signaling and in vivo prostate tumor growth (2019) (0)
Diisopropyl Tartrate Modified (E)-γ-((Cyclohexyloxy) dimethylsilyl)- and (E)-γ-(Dimethylphenylsilyl)allylboronates. Chiral Reagents for the Enantio- and Diastereoselective Synthesis of anti 1,2-Diols and 2-Butene-1,4-diols via the Formal α- and . gamma.-Hydroxyallylation of Aldehydes. (1992) (0)
Stereochemistry of the Reactions of Substituted Allylboronates with Chiral Aldehydes. (1986) (0)
1‐(1‐Naphthyl)ethyl isocyanate 1 (2006) (0)
TOTAL SYNTHESIS OF (-)-PTILOCAULIN (1984) (0)
4,6‐Diphenylthieno[3,4‐][1,3]dioxol‐2‐one 5,5‐dioxide (2006) (0)
Diastereofacially Selective Enolate Claisen Rearrangements of (4-7-. eta.4-(1-Acyloxy-2,4,6-octatrienyl))tricarbonyliron Complexes. (2010) (0)
A three-component coupling strategy for tetrahydrofuran synthesis: application of the diisopropyl tartrate modified (E)-gamma-(dimethylphenylsilyl)allylboronate as an alpha,gamma-allyl dianion equivalent. (2000) (0)
Enantioselective Synthesis of anti- and syn-Homopropargyl Alcohols via Chiral Broensted Acid Catalyzed Asymmetric Allenylboration Reactions. (2012) (0)
Isopropylidene diazomalonate 1 (2006) (0)
Ethenesulfonyl chloride–Trimethylamine (2006) (0)
Dimethylformamide–Dimethyl sulfate adduct (2006) (0)
An Improved Synthesis of Naphthoate Precursors to Olivin. (1993) (0)
Pyridazine 1-oxide 1 (2006) (0)
Sodium cyanide–Alumina (2006) (0)
Identification of Target Pathways Induced By the Multiple Myeloma Tumor Microenvironment Using Activity-Based Protein Profiling and Ex Vivo Protein Kinase Inhibitor Screening (2016) (0)
Lead carbonate, basic (2006) (0)
Synthesis of Naphthyl A-B Disaccharides (I), (II) Corresponding to Olivomycin A and Mithramycin. (1994) (0)
Mercury(II) Thiocyanate (2006) (0)
1‐Chloro‐1‐dimethylaminoisoprene 1 (2006) (0)
Silver iododibenzoate (Prévost reagent) (2006) (0)
A Highly Stereoselective Total Synthesis of the Natural Enantiomer of Olivin (XIIb). (1988) (0)
Tetrakis(triphenylphosphine)nickel(0) (2017) (0)
Compositions therapeutiques et procedes (2006) (0)
cis-Selective Hydroboration ofAllenes (2010) (0)
2‐Pyridinesulfenyl bromide and chloride (2006) (0)
Bis(o-methylaminophenyl) disulfide (2006) (0)
An Intramolecular Diels—Alder Approach to the Spirotetronic Acid Subunits of the Quartromicins. (1998) (0)
Table 2, Imidazopyridine derivatives of compound SR7377 (2014) (0)
Total synthesis of (.+-.)-verrucarol (2002) (0)
N,N′‐Disuccinimidyl carbonate 1 (2006) (0)
Methylketene methyl trimethylsilyl acetal 1 (2006) (0)
trans‐2,3‐Bis(diphenylphosphine)bicyclo‐[2.2.1]hept‐5‐ene (Norphos) (2006) (0)
Table 4, SAR of R1 Analogs (2011) (0)
4,4‐Dimethyl‐1,3‐oxathiolane‐3,3‐dioxide 1 (2006) (0)
[Table], Wee1 SAR Table (Scaffold 2: pyrazolyl pyrimidone; there are no probes in this scaffold) (2011) (0)
Synthesis of syn- and anti-β-Hydroxy Allylsilanes (2011) (0)
Bis(o‐nitrophenyl) phenylphosphonate (2006) (0)
Asymmetric Allylborations of 3-Decynaldicobalt Hexacarbonyl: Cobalt- Induced Reversal of Enantioselectivity and Applications to Highly Diastereoselective Intramolecular Pauson-Khand Reactions. (1992) (0)
Table 11, Ricerca profiling of probe ML322: SID 103771539 /CID49800087 (2014) (0)
Cobalt(III) acetate (2006) (0)
Vanadium(II) perchlorate (2006) (0)
Diisopropyl Tartrate E‐γ‐(Dimethylphenylsilyl)allylboronate, a Chiral Allylic Alcohol β‐Carbanion Equivalent for the Enantioselective Synthesis of 2‐Butene‐1,4‐diols from Aldehydes. (1992) (0)
SYNTHESE DE CLASTO-LACTACYSTINE β-LACTONE ET DE SES ANALOGUES (1998) (0)
A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma (2019) (0)
Stereoselective N‐Acylation Reactions of α‐Alkoxy Carbamates. (1998) (0)
Dimethyl sulfoxide–3‐Sulfopropanoic anhydride complex 1 (2006) (0)
Sodium borohydride–Alumina (2006) (0)
Sodium bis(2‐methoxyethoxy)aluminum hydride (SMEAH, Red‐AlÒ) (2009) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor ( R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-( 2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. (2014) (0)
[Table], Wee1 SAR Table (Scaffold 3: pyrrolo-benzoxadiazole N-oxide; there are no probes in this scaffold) (2011) (0)
Figure 4, [a, Wild type (hsf-1+/+) and...]. (2013) (0)
1‐Methoxy‐3‐methyl‐1‐trimethylsilyloxy‐1,3‐butadiene 1 (2006) (0)
(1,3‐Butadien‐1‐yl)dimethylsulfonium tetrafluoroborate (2006) (0)
Abstract 2525: Identification and characterization of class I HDAC-specific small-molecule inhibitors with a novel pharmacophore (2014) (0)
Casein Kinase 1 δ Dependent Wee 1 Degradation * (2014) (0)
Diastereoselective Aldol Reactions of Chiral Aldehydes and Chiral Methyl Ketones: Dependence of Stereoselectivity on the Metal Enolate, the Aldehyde 2,3-Stereochemistry, and the Aldehyde β-Alkoxy Protecting Group. (1995) (0)
[Table, VIM-2 Ki Assay (AID 2128)]. (2011) (0)
A Highly Stereoselective Synthesis of the Octahydronaphthalene Subunit of Kijanolide and Tetronolide. (1988) (0)
Potassium hydride‐Crown ethers (2006) (0)
N‐(2,3‐Epoxypropylidene)cyclohexylamine N‐oxide 1 (2006) (0)
Bis(dibenzylideneacetone)palladium(0) (2017) (0)
Figure 6, Structures of prior art compounds SL201 and SL209 (2014) (0)
T1171 High-Throughput Screening (HTS) of a 290,000-Small Molecule Compound Library for Inhibitors of the Gene Encoding the Pro-Proliferative Human KrüPpel-Like Factor 5 (KLF5) (2010) (0)
Figure 5, Probe development overview (post-HTS) (2014) (0)
Benzocyclobutenedione monoethylene ketal (2006) (0)
Studies on the Synthesis of Pectenotoxin II: Synthesis of a C(11)—C(26) Fragment Precursor (VI) via [3 + 2]-Annulation Reactions of Chiral Allylsilanes. (2001) (0)
Chiral Nucleophilic Addition Reactions (2009) (0)
Table 2, uHTS campaign summary and results (2011) (0)
Cerium(III) Chloride (2011) (0)
Methyl iodide—1,3‐Propanedithiol (2006) (0)
Figure 1, LC-MS of probe ML178 (2011) (0)
Dicarbonyl(cyclopentadienyl)[(dimethylsulfonium)methyl]iron tetrafluoroborate (2006) (0)
Dimethyl sulfoxide–Acetic anhydride (2006) (0)
N-Chlorosuccinimide-Dimethyl sulfide (Corey-Kim reagent) (2006) (0)
[3+2]-Cycloaddition Reactions (2009) (0)
Thioanisole–Trifluoromethanesulfonic acid (2006) (0)
The Asymmetric Allylboration Reaction: Dependence of Rate and Enantioselectivity on the Chiral Auxiliary. (1990) (0)
Methyl 3-(N,N-dimethylamino)propionate (2006) (0)
Table 1, Overview of PubChem assays for NOX1 inhibitor project (2011) (0)
TRPML3/2 Agonist SAR Table 2, Sulfonylaryl piperazines Scaffold (2011) (0)
Mercury(II) Trifluoroacetate (2011) (0)
Morita–Baylis–Hillman Reactions (2009) (0)
t‐butyl hydroperoxide–Diaryl diselenides (2006) (0)
Stereoselective Synthesis of Z,E‐2‐Bromodienes via the Palladium(0)‐ Catalyzed Cross Coupling Reactions of 1,1‐Dibromoolefins and Vinylboronic Acids. (1992) (0)
[Table], STAT3 Activators SAR Table (Isoxazole Carboxamide Scaffold) (2010) (0)
[Table, Profiling Assays]. (2011) (0)
Osmium tetroxide–Potassium chlorate (2006) (0)
Sodium cyanide–Dimethyl sulfoxide (2006) (0)
Highly Regioselective Tandem Morita-Baylis-Hillman/Aldol Cyclization (2006) (0)
Grignard reagents‐1,4‐Bis(dimethylamino)‐2,3‐dimethoxybutane (2006) (0)
Conversion of Limonene into Diene 12 Scheme 3 . Conversion of Dihydroxylation Products into Desired Isomer 6 and Initial Ireland (2017) (0)
2‐Benzoylthio‐1‐methylpyridinium chloride 1 (2006) (0)
Figure 1, Stability of Probes ML177 and ML118 (2013) (0)
Methyl α‐benzalaminocrotonate 1 (2006) (0)
Enantioselective Synthesis of α‐Methylene‐β‐hydroxy Carboxylic Acid Derivatives via a Diastereoselective Aldol/β‐Elimination Sequence: Application to the C(15)—C(21) Fragment of Tedanolide C. (2010) (0)
A211 30 day Outcomes Comparison Between Sleeve and Roux en Y Bypass in Solid Organ Transplant Recipients: Metabolic and Bariatric Surgery Accreditation and Quality Improvement Project (MBSAQIP) Analysis (2019) (0)
Iodine–Silver acetate (2006) (0)
Fluorine–Sodium trifluoroacetate (2006) (0)
Manganese(II) iodide (2006) (0)
Asymmetric Synthesis Using Tartrate Ester-Modified Allylboronates. Part 2. Single and Double Asymmetric Reactions with Alkoxy-Substituted Aldehydes. (1990) (0)
t‐Butyldimethylsilyl perchlorate (2006) (0)
JCB_201409056 1..15 (2015) (0)
Studies on the Synthesis of (-)-Spinosyn A: Application of the Steric Directing Group Strategy to Transannular Diels—Alder Reactions. (2010) (0)
Diisobutylaluminum 2,6-di-t-butyl-4-methylphenoxide (2006) (0)
Figure 1, ROR Probe Stability (2013) (0)
Synthesis of Amphidinolide E (2007) (0)
Enantioselective Synthesis of the Bottom-Half of Chlorothricolide. (1986) (0)
Ketene bis(phenylthio)ketal (2006) (0)
Titanium(IV) chloride–N-Methylaniline (2006) (0)
Dimethyl sulfoxide–Methanesulfonic anhydride (2006) (0)
Asymmetric Synthesis Using Tartrate Ester Modified Allylboronates. Part 1. Factors Influencing Stereoselectivity. (1990) (0)
Synthesis and Transannular Diels-Alder Reactions of E,E,E- Cyclotetradeca-2,8,10-trienones. (1993) (0)
SAR Table 3, Analogs (2014) (0)
Figure 2, Synthesis of VIM-2 Inhibitor Probe CID 53362017 (ML302) (Compound 2) (2014) (0)
ENANTIO- AND STEREOSELECTIVE SYNTHESES OF THE DIHYDROXYOCTADIENOIC ACID FRAGMENTS OF THE RORIDINS AND TRICHOVERRINS (1983) (0)
[Table], STAT3 Activator Probe Information (Isoxazole Carboxamide Scaffold; MLS 000522376) (2010) (0)
Abstract PR16: A new class of small molecule acetyltransferase inhibitors discovered through high-throughput screening are potent anticancer agents with cancer-type specific activity (2013) (0)
Potassium permanganate (2015) (0)
Reactions of Diisopropyl Tartrate Modified Allyl- and (E)- and (Z)-Crotylboronates with β-Alkoxy-α-methylpropionaldehydes: A Reagent Based Solution to the Acyclic Dipropionate Problem. (1987) (0)
Bis(trimethylsilyl) monoperoxysulfate (2006) (0)
Total Synthesis of Amphidinolide E (Ia) and Amphidinolide E Stereoisomers. (2007) (0)
Tributyl (iodomethyl)tin (2006) (0)
Asymmetric Allylboration of 2-N,3-O-Isopropylidene-N-Boc-L-serinal: Diastereoselective Synthesis of the Calicheamicin γI 1 Amino Sugar. (1995) (0)
2‐Chloro‐3‐ethylbenzoxazolium tetrafluoroborate 1 (2006) (0)
Diisobutylaluminum Hydride (DIBAH, DIBAL) (2009) (0)
Mercury(II) oxide (2006) (0)
Hydrogen peroxide–Potassium carbonate (2006) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor ( R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-2',3, 5'-trifluoro-(1,1'-biphenyl)-4-carboxamide (2014) (0)
Diethyl N‐benzylideneaminomethylphosphonate (2006) (0)
Table 5, NIMH’s Psychoactive Drug Screening Program results for compound 1 (2011) (0)
Figure 6, Mixed mode of inhibition for VIM-2 and IMP-1 (2014) (0)
N‐Chlorosuccinimide‐Benzeneselenenyl chloride (2006) (0)
CK1δ: an exploitable vulnerability in breast cancer. (2016) (0)
Crystal structure of Casein kinase I isoform delta (CK1 delta) complexed with SR4133 inhibitor (2020) (0)
Trichothecene Degradation Studies. Part 3. Synthesis of 12,13-Deoxy- 12,13-methanoanguidine (I) and 12-Epianguidine (II), Two Optically Active Analogues of the Epoxytrichothecene Mycotoxin Anguidine. (1987) (0)
Highly Stereoselective 1,4-Addition Reactions of Alkyliden Malonate Substituted η4-(1,3-Butadienyl)iron(tricarbonyl) Complexes. (1995) (0)
[Table, Dose Response Curves for Probes]. (2011) (0)
α-Arylation of Enones with Hypervalent Bismuth Reagents (2009) (0)
SAR Table 1, STAT3 Inhibitor SAR Table (Thienopyrimidine Scaffold) (2011) (0)
2,4-Bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide (Lawesson's reagent) (2006) (0)
E-Selective Allylboration of α-Substituted Allylboronates (2010) (0)
1,3‐Dibutoxypropene 1 (2006) (0)
Table 2, ROR Probe Comparison (2013) (0)
Figure 11, Concentration response curve for probe ML346 (2013) (0)
Magnesium Bromide Etherate (2017) (0)
Enantioselective Synthesis of (Z)- and (E)-2-Methyl-1,5-anti-pentenediols via an Allene Hydroboration—Double-Allylboration Reaction Sequence. (2013) (0)
Dimethyl sulfoxide–t‐Butyl bromide (2006) (0)
Abstract C269: Targeting casein kinase 1 delta and epsilon (CK1δ/ε) in breast cancer therapeutics. (2013) (0)
Dimethyl acetylenedicarboxylate (DMAD) (2006) (0)
Recent studies in carbonyl allylation reactions: application to the synthesis of oxygen heterocycles (2004) (0)
Mesityloxytris(dimethylamino)phosphonium azide (2006) (0)
Potassium t‐amyloxide (2009) (0)
A Stereochemically General Synthesis of Methyl 2,4,6-Trideoxy-4- methylthio-α-D-ribo-pyranoside, the Thio Sugar of Esperamicin A1. (1994) (0)
1,1‐Dibromoalkyllithium reagents (2006) (0)
Figure 4, Synthetic schemes for probe compound 1 (2011) (0)
Chemical Therapeutics Small-Molecule Inhibitors of Acetyltransferase p 300 Identi fi ed by High-Throughput Screening Are Potent Anticancer Agents (2013) (0)
Trimethylamine–Sulfur dioxide (2006) (0)
Manganese(III) sulfate (2006) (0)
2‐Trimethylsilylmethyl‐1,3‐butadiene 1 (2006) (0)
Dimethyl sulfoxide–Oxalyl chloride (Swern reagent) (2006) (0)
Acylation and Kinetic Resolution of Alcohols (2009) (0)
Regioselective Allylic Displacement (2009) (0)
Trimethylselenonium hydroxide 1 (2006) (0)
Bis(trimethylsilyl) Lithiomalonate (2006) (0)
Pyridinium poly(hydrogen fluoride) (Olah's reagent) (2006) (0)
POLYMER-BOUND TOSYL AZIDE (1974) (0)
Abstract 950: New strategy to sensitize pancreatic and bladder cancer to gemcitabine (2018) (0)
Boron trifluoride–ethanethiol (2006) (0)
Total Synthesis of Olivomycin AJ. Am. Chem. Soc.1999,121, 1990−1991 (1999) (0)
Diisopropyl Tartrate Modified E‐γ‐((Cyclohexyloxy)dimethylsilyl) allylboronate, a Chiral Reagent for the Enantioselective Synthesis of anti‐1,2‐Diols via the Formal α‐Hydroxyallylation of Aldehydes. (1992) (0)
Acetic anhydride–Pyridine (2006) (0)
Lithium aluminum hydride–Boron trifluoride etherate (2006) (0)
Silver nitrate (1988) (0)
(E)-1-Methoxy-3-trimethylsilyloxy-1,3-butadiene (Danishefsky's diene) (2006) (0)
Tricothecenes Mycotoxin Studies. (1983) (0)
α,α-2-Diphenylphosphinoferrocenyl ethyldimethylamine (2006) (0)
Acetaldehyde N-t-butylimine (2006) (0)
Extension of Chromatographically Derived Molecular Recognition Concepts to First‐Order Asymmetric Transformations (1989) (0)
Table 1, Substituted thienopyrimidines as STAT3 inhibitors (2011) (0)
Ethyl 3‐bromo‐2‐hydroxylminopropanoate (2006) (0)
Dimethylformamide dineopentyl acetal 3 (2006) (0)
4‐Dimethylaminopyridine (DMAP) (2013) (0)
Table 6, Round 1 Analogs: Alphascreen results (2014) (0)
Sodium chloride–Dimethylformamide (2006) (0)
Crystal structure of Trypanosoma cruzi CYP51 bound to the sulfonamide derivative of the 4-aminopyridyl-based inhibitor (2014) (0)
[Table], WEE1 Degradation Inhibitor SAR Table (Scaffold 1: 4-alkoxy quinolone scaffold) (2011) (0)
Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777) (2000) (0)
[Table, Structure verification with 1H NMR and LCMS results]. (2011) (0)
[Table], Summary Table of Screening Results (2010) (0)
SYNTHESIS OF (S,S)-DIISOPROPYL TARTRATE (E)-CROTYLBORONATE AND ITS REACTION WITH ALDEHYDES: (2R,3R,4R)-1,2-DIDEOXY-2-ETHENYL-4,5-O-(1-METHYLETHYLIDENE)-XYLITOL. (2012) (0)
Table 2, Compounds submitted to the MLSMR (2011) (0)
Analytical Resolution of Secondary Methyl Ethers by Chiral Complexation Gas Chromatography. (1987) (0)
Synthesis of (+)-Superstolide A (2008) (0)
Figure 3, Probe ML346 (“F1”) induces chaperone protein expression (2013) (0)
Trichothecene Degradation Studies. Part 2. Synthesis of (13-14C)Anguidine (I). (1987) (0)
[Table], PubChem BioAssay Table (2011) (0)
9-Borabicyclo[3.3.1]nonane (2011) (0)
Table 8, Probe ML322 is not a strong inhibitor of cytochrome P450 enzymes (2014) (0)
9‐Borabicyclo[3.3.1]nonane (9‐BBN) (2006) (0)
Table 1, Hsp70 Activators PubChem Summary* (2013) (0)
O-Ethylperoxycarbonic acid (2006) (0)
Table 5, SAR of R2 Analogs (2011) (0)
Probe Report for Activators of Small Heterodimer Partner (SHP) (2008) (0)
2‐Hydroxymethyl‐1‐[(1‐methylpyrrolidin‐2‐yl)‐methyl]pyrrolidine 1 (2006) (0)
Figure 9, HCV Infectivity assay method (2014) (0)
t‐Butyl hydroperoxide (TBHP) (2006) (0)
Aluminum chloride–Ethanethiol (2006) (0)
Defensive Spiroketals from Asceles glaber (Phasmatodea): Absolute Configuration and Effects on Ants and Mosquitoes (2012) (0)
Table 9, Hepatic Microsome Stability of Selected HCV Core Inhibitors (2014) (0)
Table 3, SAR Summary (2013) (0)
Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (0)
Figure 3, HCV Core dimerization HTS campaign overview (2014) (0)
Copper(II) sulfate–Pyridine (2006) (0)
Thallium(I) acetate–Iodine (2006) (0)
Silica (Silica gel) (2006) (0)
Mercury(II) Acetate (2011) (0)
Asymmetric Morita–Baylis–Hillman Reactions (2009) (0)
Stereoselective Synthesis of 2-Methyl-3-butene-1,2-diols (2010) (0)
Directed Openings of 2,3-Epoxy Alcohols via Reactions with Isocyanates: Synthesis of (+)-erythro-Dihydrosphingosine. (1986) (0)
Table 3, Selectivity of parent hit and probe compounds compared to that of chlorpromazine (2011) (0)
Dimethyl sulfoxide–N-Bromosuccinimide (2006) (0)
Sodium borohydride–Cerium(III) chloride (Luche reagent) (2006) (0)
Tetrabutylammonium Fluoride, TBAF (2009) (0)
Boron trifluoride–methanol (2006) (0)
Sodium hydroxymethyl sulfoxylate (“Rongalite”) (2006) (0)
6‐Carboxy‐5‐carbomethoxy‐7‐oxabicyclo[2.2.1]heptene‐2 1 (2006) (0)
3‐Acetyl‐4‐oxazoline‐2‐one 1 (2006) (0)
Lithium 2,2,6,6‐Tetramethylpiperidide, LiTMP (2017) (0)
Enantio- and Diastereoselective Synthesis of syn-β-Hydroxy-α-alkenyl Carboxamides via Reductive Aldol Reactions of Morpholine 4-Methyl-2,3-pentadienoic Carboxamide with Diisopinocampheylborane. (2015) (0)
[Table], Table of Probe Properties (ML115) (2010) (0)
Methoxydimethylsilyl)(trimethylsilyl)methane (2001) (0)
4‐Hydroxy‐2,2,6,6‐tetramethylpiperidinooxy radical 1 (2006) (0)
[Table, SAR Tables]. (2011) (0)
Sodium azide–Triphenylphosphine (2006) (0)
Lithium aluminum hydride‐Di‐μ‐carbonyldecacarbonyltritrianguloiron (2006) (0)
Abstract P6-15-12: Preclinical Evaluation of a STAT3 Inhibitor in Breast Cancer (2010) (0)
Butyllithium‐Hexamethylphosphoric Triamide (2006) (0)
Table 3, Solubility of ML302 (2014) (0)
Cerium(III) sulfate (2006) (0)
Studies on the Synthesis of Tedanolide. Part 2. Stereoselective Synthesis of a Protected C(1)—C(12) Fragment. (2003) (0)
The Morita–Baylis–Hillman Reaction Using Air-Stable Phosphine Reagents (2009) (0)
Dimethylformamide–Thionyl chloride (2006) (0)
Synthesis of the Naphthoquinone Nucleus of Awamycin. (2010) (0)
Application of the Steric Directing Group Strategy to the Stereoselective Synthesis of the Octahydronaphthalene Substructure of Kijanolide and Tetronolide. (2010) (0)
TOTAL SYNTHESIS OF CARBOHYDRATES, PART 4. SYNTHESIS OF MYCAROSE AND EPI-AXENOSE FROM NON-CARBOHYDRATE PRECURSORS (1985) (0)
Dimethyl sulfoxide (DMSO) (2006) (0)
Copper(I) Iodide (2017) (0)
Table 1, Summary of Performed Assays (2011) (0)

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