William Pearson
#29,030
Most Influential Person Now
Professor of Biochemistry and Molecular Genetics at the University of Virginia
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William Pearson biology Degrees
Biology
#1421
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#2391
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Biochemistry
#365
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#437
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Molecular Biology
#519
World Rank
#532
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Biology
Why Is William Pearson Influential?
(Suggest an Edit or Addition)According to Wikipedia, William Raymond Pearson is professor of biochemistry and molecular Genetics in the School of Medicine at the University of Virginia. Pearson is best known for the development of the FASTA format. Education Pearson graduated with a BS in chemistry from the University of Illinois Urbana-Champaign. He received his PhD in 1977 from Caltech. As a graduate student, he published several papers describing computer programs for analyzing biological data.
William Pearson 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Improved tools for biological sequence comparison. (1988) (10916)
- Rapid and sensitive protein similarity searches. (1985) (3572)
- Rapid and sensitive sequence comparison with FASTP and FASTA. (1990) (2050)
- Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. (1988) (788)
- Current Protocols in Bioinformatics (2002) (760)
- Flexible sequence similarity searching with the FASTA3 program package. (2000) (638)
- Nomenclature for human glutathione transferases. (1992) (633)
- Comparison of DNA sequences with protein sequences. (1997) (618)
- Searching protein sequence libraries: comparison of the sensitivity and selectivity of the Smith-Waterman and FASTA algorithms. (1991) (571)
- The genome of Cryptosporidium hominis (2004) (505)
- Comparison of methods for searching protein sequence databases (1995) (370)
- Effective protein sequence comparison. (1996) (360)
- Empirical statistical estimates for sequence similarity searches. (1998) (346)
- Nomenclature for mammalian soluble glutathione transferases. (2005) (296)
- An Introduction to Sequence Similarity (“Homology”) Searching (2013) (280)
- Using the FASTA program to search protein and DNA sequence databases. (1994) (264)
- Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13. (1993) (240)
- Characterization of the Human Class Mu GlutathioneS-Transferase Gene Cluster and the GSTM1Deletion* (1998) (217)
- Getting More from Less (2002) (173)
- A program for least squares analysis of reassociation and hybridization data. (1977) (171)
- The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes (2013) (166)
- Aligning two sequences within a specified diagonal band (1992) (160)
- Molecular characterization of α1- and α2-adrenoceptors (1991) (140)
- Evolution of protein sequences and structures. (1999) (140)
- Sensitivity and selectivity in protein structure comparison (2004) (132)
- Dynamic programming algorithms for biological sequence comparison. (1992) (112)
- Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. (1983) (111)
- White Paper: Designing Medical Informatics Research and Library-Resource Projects to Increase What Is Learned (1994) (109)
- Selecting the Right Similarity‐Scoring Matrix (2013) (109)
- Phylogenies of glutathione transferase families. (2005) (98)
- The limits of protein sequence comparison? (2005) (92)
- Heterologous expression of the allelic variant mu-class glutathione transferases μ and ψ (1991) (86)
- Identification of Residues in Glutathione Transferase Capable of Driving Functional Diversification in Evolution (2003) (86)
- Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus. (1993) (86)
- Finding Protein and Nucleotide Similarities with FASTA (2003) (85)
- The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors. (1992) (83)
- Rapid Identification of Protein Phosphatase 1-binding Proteins by Mixed Peptide Sequencing and Data Base Searching (1998) (81)
- MACiE: exploring the diversity of biochemical reactions (2011) (80)
- Homozygous deletion of gene for glutathione S-transferase M1 in bladder cancer. (1993) (78)
- The EF-Hand, Homologs and Analogs (1991) (77)
- Characterization of the tomato (Lycopersicon esculentum) genome using in vitro and in situ DNA reassociation (1998) (74)
- Empirical determination of effective gap penalties for sequence comparison (2002) (74)
- Bioinformatics core competencies for undergraduate life sciences education (2017) (68)
- Finding Protein and Nucleotide Similarities with FASTA (2003) (65)
- Tissue-specific induction of murine glutathione transferase mRNAs by butylated hydroxyanisole. (1988) (63)
- Homologous over-extension: a challenge for iterative similarity searches (2010) (58)
- Aligning a DNA sequence with a protein sequence (1997) (58)
- Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus. (1991) (54)
- Generalized neighbor-joining: more reliable phylogenetic tree reconstruction. (1999) (53)
- On the Primer Selection Problem in Polymerase Chain Reaction Experiments (1996) (50)
- Identifying distantly related protein sequences (1991) (49)
- BLAST and FASTA similarity searching for multiple sequence alignment. (2014) (48)
- A Strategy for the Rapid Identification of Phosphorylation Sites in the Phosphoproteome * (2002) (48)
- Analysis of rat repetitive DNA sequences. (1978) (42)
- Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1. (1999) (41)
- Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction (2017) (41)
- Automatic construction of restriction site maps (1982) (39)
- Absence of short period interspersion of repetitive and non-repetitive sequences in the DNA of Drosophila melanogaster (1976) (39)
- Entamoeba histolytica: sequence conservation of the Gal/GalNAc lectin from clinical isolates. (2002) (36)
- Identifying distantly related protein sequences. (1997) (35)
- Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster. (1999) (34)
- Exploring the relationship between sequence similarity and accurate phylogenetic trees. (2006) (34)
- A platform for biological sequence comparison on parallel computers (1990) (33)
- Training for bioinformatics and computational biology (2001) (33)
- Protein sequence comparison and protein evolution (1995) (32)
- Statistical Significance in Biological Sequence Comparison (2004) (31)
- Regulation of Synthesis of Amyloid A‐Related Protein * (1982) (31)
- PSI-Search: iterative HOE-reduced profile SSEARCH searching (2012) (30)
- Stoichiometry of chromatin proteins. (1974) (30)
- Heterologous expression of the allelic variant mu-class glutathione transferases mu and psi. (1991) (28)
- Panning for genes--A visual strategy for identifying novel gene orthologs and paralogs. (1999) (27)
- Most partial domains in proteins are alignment and annotation artifacts (2015) (26)
- Computer programs for analysis of nucleic acid hybridization, thermal denaturation, and gel electrophoresis data. (1979) (23)
- The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole. (1993) (21)
- Identification and characterization of GSTT3, a third murine Theta class glutathione transferase. (2002) (21)
- Query-seeded iterative sequence similarity searching improves selectivity 5–20-fold (2016) (21)
- Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB’s Education Committee) (2016) (20)
- Using the FASTA program to search protein and DNA sequence databases. (1994) (19)
- Globally, unrelated protein sequences appear random (2010) (18)
- Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments (2010) (18)
- Protein Function Prediction: Problems and Pitfalls (2015) (16)
- Repeated DNA sequences near the 5'-end of the silk fibroin gene. (1981) (16)
- Sequence organization of the rat genome by electron microscopy. (1978) (16)
- A New Approach to Primer Selection in Polymerase Chain Reaction Experiments (1995) (14)
- Comparing machine-independent versus machine-specific parallelization of a software platform for biological sequence comparison (1992) (14)
- RefProtDom: a protein database with improved domain boundaries and homology relationships (2010) (14)
- Molecular characterization of alpha 1- and alpha 2-adrenoceptors. (1991) (13)
- Adjusting scoring matrices to correct overextended alignments (2013) (12)
- Visualization of near-optimal sequence alignments (2004) (11)
- MIF proteins are not glutathione transferase homologs (1994) (10)
- Sequence relationship between long and short repetitive DNA of the rat: a preliminary report. (1977) (10)
- Primary structure of avian H+/K+-ATPase β-subunit (1994) (10)
- CRP: Cleavage of Radiolabeled Phosphoproteins (2003) (10)
- A System for Visualizing and Analyzing Near-Optimal Protein Sequence Alignments (2005) (9)
- MOLECULAR CLONING AND SEQUENCING OF CALBINDIN-D9K CDNA FROM MOUSE PLACENTA. (1988) (8)
- Kinetic determination of the genome size of the pea. (1978) (7)
- Protein sequence comparison and Protein evolution Tutorial - ISMB2000 (2001) (7)
- Discrete-length repeated sequences in eukaryotic genomes. (1981) (6)
- Improved tools for biological sequence comparison ( amino acid / nucleic acid / data base searches / local similarity ) (6)
- Differences in induction by xenobiotics in murine tissues and the Hepa1c1c7 cell line of mRNAs encoding glutathione transferase, quinone reductase, and CYP1A P450s. (1993) (5)
- FASTA Search Programs (2014) (5)
- Long and short repeats of sea urchin DNA and their evolution (2004) (5)
- Corrigendum: The genome of Cryptosporidium hominis (2004) (5)
- Using Relational Databases for Improved Sequence Similarity Searching and Large‐Scale Genomic Analyses (2004) (5)
- Using SQL Databases for Sequence Similarity Searching and Analysis (2017) (5)
- Environmental Costs — Impact on Dredging (1976) (4)
- Classification of Adrenergic Receptor Subtypes: Molecular Biologic Approaches (1994) (3)
- Identification of Homologs (2019) (1)
- Primary structure of avian H+/K(+)-ATPase beta-subunit. (1994) (1)
- Identification of Class-mu Glutathione Transferase Genes GSTM I-GSTMS on Human Chromosome I p 1 3 (2006) (1)
- Making Change Sustainable: Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) Meeting Review (2022) (1)
- Searching Protein Sequence Databases — Is Optimal Best? (1994) (1)
- Increased Synthesis of Glutathione S-Transferases in Response Anticarcinogenic Antioxidants (2001) (1)
- Title Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments Permalink (2010) (0)
- CABIOS INVITED REVIEW Identifying distantly related protein sequences (1997) (0)
- Nucleic Acids Research Automatic construction of restriction site maps (0)
- Beyond Stamp Collection: Insights from Genome [Biology?] (2002) (0)
- STATISTICAL SIGNIFICANCE IN BIOLOGICAL SEQUENCE COMPARISON 1 (2000) (0)
- Characterization of Bacterial Genome Sequences by Similarity Searching (2007) (0)
- Non-comedogenic needle (1996) (0)
- Most partial domains in proteins are alignment and annotation artifacts (2015) (0)
- Sensitivity and Selectivity in Protein Sequence Comparison (1987) (0)
- Faculty Opinions recommendation of A map of constrained coding regions in the human genome. (2018) (0)
- 1) Nomenclature for Mammalian Soluble (2005) (0)
- Method for bonding ceramic foam materials. (1999) (0)
- Faculty Opinions recommendation of Discovering viral genomes in human metagenomic data by predicting unknown protein families. (2018) (0)
- Faculty Opinions recommendation of A statistical test for conserved RNA structure shows lack of evidence for structure in lncRNAs. (2017) (0)
- RECOVERY OF HYDROGEN FLUORIDE FROM A COOLANT-114-HYDROGEN FLUORIDE MIXTURE (1960) (0)
- Cloning , expression , and characterization of a class-mu glutathione transferase from human muscle , the product of the GST 4 locus ( cDNA sequence / gene conversion / expression in Escherichia coli / reaction mechanism ) (0)
- Identifying features in biological sequences: Sixth workshop report (1995) (0)
- Comparison of detection methods and genome quality when quantifying nuclear mitochondrial insertions in vertebrate genomes (2022) (0)
- Protein Sequence Analysis (2002) (0)
- BIOINFORMATICS ORIGINAL Globally, unrelated protein sequences appear random (0)
- Faculty Opinions recommendation of Human contamination in bacterial genomes has created thousands of spurious proteins. (2019) (0)
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