William T. Cefalu
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American physician-scientist
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(Suggest an Edit or Addition)According to Wikipedia, William T. Cefalu is an American physician-scientist. Cefalu is the chief scientific and medical officer of the American Diabetes Association. Education Cefalu completed a B.S. from Southeastern Louisiana University and an M.D. from LSU Health Sciences Center New Orleans in 1979. He was a resident in internal medicine and chief resident at University of California, Irvine, Veterans Affairs Long Beach Healthcare System. He conducted a fellowship in endocrinology at David Geffen School of Medicine at UCLA.
William T. Cefalu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice (2009) (1566)
- Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range (2019) (1526)
- How Do We Define Cure of Diabetes? (2009) (896)
- Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes. (2018) (677)
- Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial (2013) (612)
- Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise (2013) (576)
- Role of Chromium in Human Health and in Diabetes (2004) (555)
- Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels (2010) (390)
- Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women. (2010) (346)
- Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a Diabetes Care Editors’ Expert Forum (2017) (314)
- Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study (2001) (304)
- Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring (2018) (297)
- Bioavailability of albumin-bound testosterone. (1985) (263)
- Adipocyte iron regulates adiponectin and insulin sensitivity. (2012) (256)
- A natural history of botanical therapeutics. (2008) (249)
- 2018 ACC Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. (2018) (247)
- Insulin Resistance: Cellular and Clinical Concepts (2001) (227)
- Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats. (2002) (224)
- Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. (2008) (218)
- Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. (1999) (211)
- Contribution of visceral fat mass to the insulin resistance of aging. (1995) (209)
- Defining Insulin Resistance From Hyperinsulinemic-Euglycemic Clamps (2012) (204)
- Inhaled Human Insulin Treatment in Patients with Type 2 Diabetes Mellitus (2001) (203)
- Animal models of type 2 diabetes: clinical presentation and pathophysiological relevance to the human condition. (2006) (192)
- An update on sodium-glucose co-transporter-2 inhibitors for the treatment of diabetes mellitus (2016) (179)
- Insulin Access and Affordability Working Group: Conclusions and Recommendations (2018) (174)
- Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes (2015) (174)
- Inhaled Insulin Improves Glycemic Control When Substituted for or Added to Oral Combination Therapy in Type 2 Diabetes (2005) (173)
- Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors’ Expert Forum (2015) (167)
- Concept, strategies, and feasibility of noninvasive insulin delivery. (2004) (166)
- Complications of type 1 diabetes. (2010) (163)
- Dietary soy protein and estrogen replacement therapy improve cardiovascular risk factors and decrease aortic cholesteryl ester content in ovariectomized cynomolgus monkeys. (1997) (156)
- Long-term efficacy and safety of canagliflozin monotherapy in patients with type 2 diabetes inadequately controlled with diet and exercise: findings from the 52-week CANTATA-M study (2014) (149)
- Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trial. (2005) (148)
- Antihyperglycemic activity of Tarralin, an ethanolic extract of Artemisia dracunculus L. (2006) (148)
- Long-term glycemic control measurements in diabetic patients receiving hemodialysis. (2002) (147)
- Exploration of simple insulin sensitivity measures derived from frequently sampled intravenous glucose tolerance (FSIGT) tests. The Insulin Resistance Atherosclerosis Study. (1995) (143)
- Personalized Management of Hyperglycemia in Type 2 Diabetes (2013) (139)
- Dapagliflozin Added to Usual Care in Individuals with Type 2 Diabetes Mellitus with Preexisting Cardiovascular Disease: A 24‐Week, Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Study with a 28‐Week Extension (2014) (139)
- Dapagliflozin’s Effects on Glycemia and Cardiovascular Risk Factors in High-Risk Patients With Type 2 Diabetes: A 24-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With a 28-Week Extension (2015) (135)
- Chromium picolinate enhances skeletal muscle cellular insulin signaling in vivo in obese, insulin-resistant JCR:LA-cp rats. (2006) (134)
- Diabetes and Aging: Unique Considerations and Goals of Care (2017) (133)
- Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen. (1995) (128)
- Does body mass index adequately convey a patient's mortality risk? (2013) (125)
- Insulin Therapy in People With Type 2 Diabetes: Opportunities and Challenges? (2014) (125)
- Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. (2011) (123)
- Effect of chromium picolinate on insulin sensitivity in vivo (1999) (123)
- Isothiocyanate-rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice. (2015) (123)
- Current Concepts About Chromium Supplementation in Type 2 Diabetes and Insulin Resistance (2010) (119)
- Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans. (2014) (117)
- Blueberries Improve Endothelial Function, but Not Blood Pressure, in Adults with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2015) (116)
- Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. (2007) (114)
- Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2020) (113)
- Elevated pregnancy losses at high and low extremes of maternal glucose in early normal and diabetic pregnancy: evidence for a protective adaptation in diabetes. (2005) (110)
- Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum (2016) (109)
- Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2020) (107)
- Effects of canagliflozin on body weight and relationship to HbA1c and blood pressure changes in patients with type 2 diabetes (2015) (105)
- Treatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen. (2002) (102)
- Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. (2010) (100)
- Glycohemoglobin measured by automated affinity HPLC correlates with both short-term and long-term antecedent glycemia. (1994) (99)
- Restrictive Transport of a Lipid‐Soluble Peptide (Cyclosporin) Through the Blood–Brain Barrier (1985) (98)
- Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors. (1983) (95)
- Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. (2008) (94)
- 20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model. (2009) (90)
- Adipocyte iron regulates leptin and food intake. (2015) (86)
- A study of caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): a potential model for aging research. (1997) (86)
- Plant-derived therapeutics for the treatment of metabolic syndrome. (2010) (84)
- Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol. (2008) (83)
- Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL. (2010) (83)
- Naturally Occurring and Experimental Diabetes in Cynomolgus Monkeys: A Comparison of Carbohydrate and Lipid Metabolism and Islet Pathology (2001) (82)
- Inactivation of the Mitochondrial Carrier SLC25A25 (ATP-Mg2+/Pi Transporter) Reduces Physical Endurance and Metabolic Efficiency in Mice* (2011) (81)
- Two-Year Pulmonary Safety and Efficacy of Inhaled Human Insulin (Exubera) in Adult Patients With Type 2 Diabetes (2007) (80)
- Phytochemical composition and metabolic performance-enhancing activity of dietary berries traditionally used by Native North Americans. (2008) (79)
- The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes (2016) (78)
- Human Adenovirus Type 36 Enhances Glucose Uptake in Diabetic and Nondiabetic Human Skeletal Muscle Cells Independent of Insulin Signaling (2008) (78)
- Glycemic targets and cardiovascular disease. (2008) (78)
- The Hurricane Katrina aftermath and its impact on diabetes care: observations from "ground zero": lessons in disaster preparedness of people with diabetes. (2006) (78)
- Clinical Considerations for Use of Initial Combination Therapy in Type 2 Diabetes (2016) (77)
- Bioactives from bitter melon enhance insulin signaling and modulate acyl carnitine content in skeletal muscle in high-fat diet-fed mice. (2011) (76)
- Absence of albumin receptor on brain capillaries in vivo or in vitro. (1985) (75)
- Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36 (2008) (74)
- Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination. (2002) (73)
- Improved absorption and bioactivity of active compounds from an anti-diabetic extract of Artemisia dracunculus L. (2009) (72)
- Effects of dietary fibers on weight gain, carbohydrate metabolism, and gastric ghrelin gene expression in mice fed a high-fat diet. (2007) (72)
- Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. (2007) (72)
- Body Mass Index and the Risk of All-Cause Mortality Among Patients With Type 2 Diabetes Mellitus (2014) (70)
- Greater Dose-Ranging Effects on A1C Levels Than on Glucosuria With LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Patients With Type 2 Diabetes on Metformin Monotherapy (2014) (69)
- Template to improve glycemic control without reducing adiposity or dietary fat. (2011) (67)
- Clinical validation of a second-generation fructosamine assay. (1991) (67)
- Bioactives of Artemisia dracunculus L enhance cellular insulin signaling in primary human skeletal muscle culture. (2008) (66)
- Impaired Insulin Sensitivity and Elevated Ectopic Fat in Healthy Obese vs. Nonobese Prepubertal Children (2012) (65)
- Professional Practice Committee: Standards of Medical Care in Diabetes—2018 (2017) (64)
- Beyond Metformin: Safety Considerations in the Decision-Making Process for Selecting a Second Medication for Type 2 Diabetes Management (2014) (63)
- Intrahepatic and intramyocellular lipids are determinants of insulin resistance in prepubertal children (2011) (63)
- Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity (2009) (63)
- Need for Regulatory Change to Incorporate Beyond A1C Glycemic Metrics (2018) (63)
- In vivo effects of dietary quercetin and quercetin-rich red onion extract on skeletal muscle mitochondria, metabolism, and insulin sensitivity (2014) (62)
- Phenotype of subjects with type 2 diabetes mellitus may determine clinical response to chromium supplementation. (2007) (62)
- Enhanced hepatic extraction of estrogens used for replacement therapy. (1986) (61)
- Effect of obesity and fertility status on sex steroid levels in men. (1993) (61)
- Inactivation of PKCθ leads to increased susceptibility to obesity and dietary insulin resistance in mice (2007) (60)
- Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans. (1998) (59)
- Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes (2021) (57)
- The effects of hormone replacement therapy on carbohydrate metabolism and cardiovascular risk factors in surgically postmenopausal cynomolgus monkeys. (1996) (55)
- Insulin sensitivity and cardiovascular risk factors in ovariectomized monkeys with estradiol alone or combined with nomegestrol acetate. (1998) (54)
- Comparative Efficacy of a Once-Daily Controlled-Release Formulation of Glipizide and Immediate-Release Glipizide in Patients With NIDDM (1994) (54)
- Is it Time to Change the Way We Report and Discuss Weight Loss? (2009) (54)
- Botanicals as epigenetic modulators for mechanisms contributing to development of metabolic syndrome. (2008) (52)
- Consensus report: definition and interpretation of remission in type 2 diabetes (2021) (51)
- An extract of Artemisia dracunculus L. enhances insulin receptor signaling and modulates gene expression in skeletal muscle in KK-A(y) mice. (2011) (51)
- Diabetes mellitus and islet amyloidosis in cynomolgus monkeys. (1996) (51)
- Islet Amyloid and Islet Amyloid Polypeptide in Cynomolgus Macaques (Macaca fascicularis): An Animal Model of Human Non-insulin-dependent Diabetes Mellitus (1996) (50)
- A Critical Analysis of the Clinical Use of Incretin-Based Therapies (2013) (50)
- Medical Management of Diabetes Mellitus (2000) (50)
- Evaluation of botanicals for improving human health. (2008) (50)
- Caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): metabolic, physiologic, and atherosclerotic measures from a 4-year intervention trial. (2004) (49)
- Aggressive Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients (2013) (49)
- Endothelial Dysfunction: An Early Cardiovascular Risk Marker in Asymptomatic Obese Individuals with Prediabetes. (2012) (49)
- Caloric restriction mimetics: physical activity and body composition changes. (2001) (48)
- Clinical Assessment of Individualized Glycemic Goals in Patients With Type 2 Diabetes: Formulation of an Algorithm Based on a Survey Among Leading Worldwide Diabetologists (2015) (48)
- Validity of Serum Fructosamine as Index of Short-Term Glycemic Control in Diabetic Outpatients (1988) (48)
- Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys (2009) (47)
- Effect of combination glipizide GITS/metformin on fibrinolytic and metabolic parameters in poorly controlled type 2 diabetic subjects. (2002) (47)
- Effects of chromium picolinate on food intake and satiety. (2008) (47)
- SGLT2 Inhibitors: The Latest “New Kids on the Block”! (2015) (46)
- Artemisia scoparia extract attenuates non-alcoholic fatty liver disease in diet-induced obesity mice by enhancing hepatic insulin and AMPK signaling independently of FGF21 pathway. (2013) (46)
- A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks (2018) (46)
- Botanicals and the metabolic syndrome. (2008) (45)
- Effect of age and caloric restriction on insulin receptor binding and glucose transporter levels in aging rats (1997) (45)
- Chronic hyperglycemia increases arterial low-density lipoprotein metabolism and atherosclerosis in cynomolgus monkeys. (1998) (45)
- Determinants of insulin-stimulated glucose disposal in middle-aged, premenopausal women. (2001) (45)
- Insulin resistance and fat patterning with aging: relationship to metabolic risk factors for cardiovascular disease. (1998) (45)
- Metabolic Surgery for Type 2 Diabetes: Changing the Landscape of Diabetes Care (2016) (45)
- Human adenovirus 36 decreases fatty acid oxidation and increases de novo lipogenesis in primary cultured human skeletal muscle cells by promoting Cidec/FSP27 expression (2010) (45)
- The integral role of clinical research in clinical care. (2003) (43)
- Effect on glycemic control of the addition of 2.5 mg glipizide GITS to metformin in patients with T2DM. (2005) (43)
- Inflammation, Insulin Resistance, and Type 2 Diabetes: Back to the Future? (2009) (42)
- HbA1c and Lower-Extremity Amputation Risk in Low-Income Patients With Diabetes (2013) (42)
- The effects of hormonal replacement therapy on insulin sensitivity in surgically postmenopausal cynomolgus monkeys (Macaca fascicularis). (1994) (41)
- Reducing the Glycemic Index or Carbohydrate Content of Mixed Meals Reduces Postprandial Glycemia and Insulinemia Over the Entire Day but Does Not Affect Satiety (2012) (41)
- Diabetes, the Metabolic Syndrome, and Angiographic Progression of Coronary Arterial Disease in Postmenopausal Women (2006) (41)
- Considerations in the Management of Gestational Diabetes Mellitus: “You Are What Your Mother Ate!” (2015) (41)
- Bioactives of Artemisia dracunculus L. Mitigate the Role of Ceramides in Attenuating Insulin Signaling in Rat Skeletal Muscle Cells (2012) (40)
- Creatine ( methyl-d3) dilution in urine for estimation of total body skeletal muscle mass: accuracy and variability vs. MRI and DXA. (2018) (40)
- Artemisia dracunculus L. polyphenols complexed to soy protein show enhanced bioavailability and hypoglycemic activity in C57BL/6 mice. (2014) (39)
- The Importance of Waist Circumference and BMI for Mortality Risk in Diabetic Adults (2013) (39)
- Safety and efficacy of inhaled human insulin (exubera) during discontinuation and readministration of therapy in adults with type 2 diabetes: a 3-year randomized controlled trial. (2009) (39)
- Blood pressure and stroke risk among diabetic patients. (2013) (38)
- Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date. (1999) (38)
- Streptozotocin-induced diabetes mellitus in cynomolgus monkeys: changes in carbohydrate metabolism, skin glycation, and pancreatic islets. (1998) (37)
- The contribution of race and diabetes status to metabolic flexibility in humans. (2010) (36)
- Paradoxical insights into whole body metabolic adaptations following SGLT2 inhibition. (2014) (35)
- The Alarming and Rising Costs of Diabetes and Prediabetes: A Call for Action! (2014) (35)
- Diabetes Care: Change Is Constant (2011) (35)
- Beta-cell function during insulin-modified intravenous glucose tolerance test successfully assessed by the C-peptide minimal model. (1999) (35)
- Pharmacotherapy for the Treatment of Patients with Type 2 Diabetes Mellitus: Rationale and Specific Agents (2007) (35)
- Patients' perceptions of subcutaneous insulin in the OPTIMIZE study: a multicenter follow-up study. (2008) (34)
- Glycemic control and cardiovascular disease--should we reassess clinical goals? (2005) (33)
- Skeletal Muscle Protein Tyrosine Phosphatase 1B Regulates Insulin Sensitivity in African Americans (2012) (32)
- Serum bioavailability and tissue metabolism of testosterone and estradiol in rat salivary gland. (1986) (32)
- Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys (2001) (32)
- American Diabetes Association–European Association for the Study of Diabetes Position Statement: Due Diligence Was Conducted (2012) (32)
- Evaluation of alternative strategies for optimizing glycemia: progress to date. (2002) (32)
- “Prediabetes”: Are There Problems With This Label? No, We Need Heightened Awareness of This Condition! (2016) (31)
- The Artificial Pancreas: Are We There Yet? (2014) (30)
- Glycation of plasma low density lipoproteins increases interaction with arterial proteoglycans. (1999) (30)
- Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome (2006) (29)
- Disrupted anabolic and catabolic processes may contribute to alcohol-accentuated SAIDS-associated wasting. (2011) (28)
- Intensive Glycemic Control and Cardiovascular Disease Observations From the ACCORD Study (2008) (28)
- Chronic caloric restriction alters muscle membrane fatty acid content☆ (2000) (28)
- Diabetes Care: “State of the Union” (2012) (28)
- Regulation of insulin action by an extract of Artemisia dracunculus L. in primary human skeletal muscle culture: A proteomics approach (2010) (27)
- Aging and atherosclerosis in human and nonhuman primates (1997) (26)
- Total Serum Glycosylated Proteins in Detection and Monitoring of Gestational Diabetes (1990) (26)
- Skeletal muscle ceramides and daily fat oxidation in obesity and diabetes. (2018) (26)
- Inactivation of PKCtheta leads to increased susceptibility to obesity and dietary insulin resistance in mice. (2007) (26)
- Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys (2004) (25)
- “TODAY” Reflects on the Changing “Faces” of Type 2 Diabetes (2013) (25)
- Lipid in Skeletal Muscle Myotubes is associated to the Donors’ Insulin Sensitivity and Physical Activity Phenotypes (2013) (25)
- Sustained efficacy and pulmonary safety of inhaled insulin during 2 years of outpatient therapy (2000) (25)
- Bioactives from Artemisia dracunculus L. enhance insulin sensitivity via modulation of skeletal muscle protein phosphorylation. (2014) (24)
- Role of glycated proteins in detecting and monitoring diabetes in cynomolgus monkeys. (1993) (24)
- The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: The “Gift” That Keeps on Giving! (2013) (24)
- Impact of Lowering BMI Cut Points as Recommended in the Revised American Diabetes Association's Standards of Medical Care in Diabetes—2015 on Diabetes Screening in Asian Americans (2015) (24)
- Chronic binge alcohol consumption alters myogenic gene expression and reduces in vitro myogenic differentiation potential of myoblasts from rhesus macaques. (2014) (23)
- Maturation of CGM and Glycemic Measurements Beyond HbA1c—A Turning Point in Research and Clinical Decisions (2017) (23)
- Inhaled insulin: a novel route for insulin delivery (2002) (23)
- Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells. (2013) (23)
- Increased glycation of plasma lipoproteins in diabetic cynomolgus monkeys. (1996) (22)
- High dose intravenous, but not low dose subcutaneous, insulin-like growth factor-I therapy induces sustained insulin sensitivity in severely resistant type I diabetes mellitus. (1994) (21)
- Randomized study to characterize glycemic control and short-term pulmonary function in patients with type 1 diabetes receiving inhaled human insulin (exubera). (2007) (20)
- Hypoglycemic potential of nateglinide versus glyburide in patients with type 2 diabetes mellitus. (2004) (20)
- Comparing the effects of nano-sized sugarcane fiber with cellulose and psyllium on hepatic cellular signaling in mice (2012) (20)
- Long‐term maintenance of efficacy of dapagliflozin in patients with type 2 diabetes mellitus and cardiovascular disease (2016) (20)
- Getting to the “Heart” of the Matter on Diabetic Cardiovascular Disease: “Thanks for the Memory” (2016) (20)
- Effect of glipizide GITS on insulin sensitivity, glycemic indices, and abdominal fat composition in NIDDM (1998) (20)
- Dietary chromium supplementation for targeted treatment of diabetes patients with comorbid depression and binge eating. (2015) (20)
- Proteomic analysis reveals cellular pathways regulating carbohydrate metabolism that are modulated in primary human skeletal muscle culture due to treatment with bioactives from Artemisia dracunculus L. (2012) (19)
- An Extract of Artemisia dracunculus L. Inhibits Ubiquitin-Proteasome Activity and Preserves Skeletal Muscle Mass in a Murine Model of Diabetes (2013) (19)
- Redefining treatment success in type 2 diabetes mellitus: Comprehensive targeting of core defects (2009) (18)
- Fractalkine: A Cellular Link Between Adipose Tissue Inflammation and Vascular Pathologies (2011) (18)
- Novel routes of insulin delivery for patients with type 1 or type 2 diabetes. (2001) (18)
- Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture (2014) (18)
- Evolving Strategies for Insulin Delivery and Therapy (2012) (18)
- Evolving Treatment Strategies for the Management of Type 2 Diabetes (2012) (17)
- Controlling hypoglycemia in type 2 diabetes: which agent for which patient? (2005) (17)
- Efficacy and Safety of Canagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, Versus Glimepiride in Patients with Type 2 Diabetes on Background Metformin (2012) (17)
- Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes. (2021) (17)
- Serum Fructosamine as a Screening Test for Diabetes in the Elderly: A Pilot Study (1993) (16)
- The Impact of Precision Medicine in Diabetes: A Multidimensional Perspective (2016) (16)
- Steps Toward the Meaningful Translation of Prevention Strategies for Type 2 Diabetes (2012) (16)
- More Evidence for a Prevention-Related Indication for Metformin: Let the Arguments Resume! (2019) (16)
- SGLT Inhibitors for Type 1 Diabetes: An Obvious Choice or Too Good to Be True? (2018) (15)
- Chromium Picolinate Supplementation Attenuates Body Weight Gain and Increases Insulin Sensitivity in Subjects With Type 2 Diabetes (2006) (15)
- Canagliflozin Demonstrates Durable Glycemic Improvements Over 104 Weeks Compared with Glimepiride in Subjects with Type 2 Diabetes Mellitus on Metformin (2013) (15)
- Psychosocial Research and Care in Diabetes: Altering Lives by Understanding Attitudes (2016) (15)
- Molecular Mechanisms for Activation of the Agouti-Related Protein and Stimulation of Appetite (2010) (15)
- Diabetes and Herbal (Botanical) Medicine (2011) (15)
- The use of hormone replacement therapy in postmenopausal women with type 2 diabetes. (2001) (15)
- Improved glucose control decreases the interaction of plasma low-density lipoproteins with arterial proteoglycans. (2002) (14)
- The Physiologic Role of Incretin Hormones: Clinical Applications (2010) (13)
- COVID-19 and metabolic diseases: a heightened awareness of health inequities and a renewed focus for research priorities (2021) (13)
- In Response to Carter and Heinemann: Insulin Concentration in Vials Randomly Purchased in Pharmacies in the United States: Considerable Loss in the Cold Supply Chain (2018) (13)
- Diabetic dyslipidemia and the metabolic syndrome (2008) (13)
- An extract of Urtica dioica L. mitigates obesity induced insulin resistance in mice skeletal muscle via protein phosphatase 2A (PP2A) (2016) (13)
- Clinical Evaluation of Serum Fructosamine in Monitoring Elderly Outpatient Diabetics (1989) (13)
- Chromium picolinate and biotin enhance glycogen synthesis and glycogen synthase gene expression in human skeletal muscle culture (2000) (12)
- A “Spoonful of Sugar” and the Realities of Diabetes Prevention! (2014) (12)
- Hepatic bioavailability of thyroxine and testosterone in familial dysalbuminemic hyperthyroxinemia. (1985) (12)
- Inverse correlation of serum inflammatory markers with metabolic parameters in healthy, Black and White prepubertal youth (2014) (12)
- Kinetics of lactate transport into rat liver in vivo. (1990) (12)
- Inhaled Insulin: A Proof-of-Concept Study (2001) (12)
- Blood pressure and heart failure risk among diabetic patients. (2014) (12)
- Diabetes Care Editors’ Expert Forum 2018: Managing Big Data for Diabetes Research and Care (2019) (12)
- Modulation of sphingolipid metabolism with calorie restriction enhances insulin action in skeletal muscle. (2015) (12)
- LA-CP RATS SHOW IMPROVED LIPID PROFILES IN RESPONSE TO DIETS CONTAINING CHROMIUM PICOLINATE AND BIOTIN (2001) (12)
- Exubera. Inhale therapeutic systems. (2002) (11)
- Pharmacotherapy for the Treatment of Patients with Type 2 Diabetes Mellitus: Rationale and Specific Agents (2007) (11)
- In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction. (2000) (11)
- Liver and Kidney Tissue Membranes As Tissue Markers for Nonenzymatic Glycosylation (1991) (11)
- Type 1 Diabetes at a Crossroads! (2015) (11)
- Overview of the Health Properties of Blueberries (2013) (11)
- Multidisciplinary interventions: mapping new horizons in diabetes care. (2008) (11)
- A synthetic anti‐inflammatory sterol improves insulin sensitivity in insulin‐resistant obese impaired glucose tolerance subjects (2013) (11)
- Clinical validity of a self-test fructosamine in outpatient diabetic management. (1999) (11)
- Economics of diabetes-cost impact of not treating diabetes early and intensively. (2004) (10)
- The DESIGNER Approach Helps Decipher the Hypoglycemic Bioactive Principles of Artemisia dracunculus (Russian Tarragon). (2019) (10)
- Artemisia supplementation differentially affects the mucosal and luminal ileal microbiota of diet-induced obese mice. (2014) (10)
- Bioactives of Artemisia dracunculus L. enhance insulin sensitivity by modulation of ceramide metabolism in rat skeletal muscle cells. (2014) (10)
- Stinging Nettle (Urtica dioica L.) Attenuates FFA Induced Ceramide Accumulation in 3T3-L1 Adipocytes in an Adiponectin Dependent Manner (2016) (10)
- Insulin’s Role in Diabetes Management: After 90 Years, Still Considered the Essential “Black Dress” (2015) (10)
- Study Design and Rationale of a Dose‐Ranging Trial of LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy (2013) (10)
- Innovative Approaches to Understanding and Addressing Health Disparities in Diabetes Care and Research (2015) (9)
- Atlas of Cardiometabolic Risk (2007) (9)
- An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin-proteasome system enzymes in skeletal muscle: potential role in the treatment of sarcopenic obesity. (2014) (9)
- An Extract of Russian Tarragon Prevents Obesity‐Related Ectopic Lipid Accumulation (2018) (9)
- Doxazosin lowers blood pressure and improves insulin responses to a glucose load with no changes in tyrosine kinase activity or insulin binding. (1995) (9)
- Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers. (2008) (8)
- Point: Pulmonary Inhalation of Insulin: Another “Brick in the Wall” (2007) (8)
- Feasibility of intravenous glucose tolerance testing prior to puberty. (2010) (8)
- Response to Comment on Cefalu et al. The Alarming and Rising Costs of Diabetes and Prediabetes: A Call for Action! Diabetes Care 2014;37:3137–3138 (2015) (8)
- Effects of insulin sensitizers on plaque vulnerability associated with elevated lipid content in atheroma in ApoE-knockout mice (2004) (8)
- Clinical effect of chromium supplements on human health (2007) (8)
- Clinical research observations with use of exubera in patients with type 1 and 2 diabetes. (2007) (7)
- Tools for the identification of bioactives impacting the metabolic syndrome: screening of a botanical extract library using subcutaneous and visceral human adipose-derived stem cell-based assays. (2012) (7)
- Effect of Shilianhua extract and its fractions on body weight of obese mice. (2008) (7)
- Consensus report: Definition and interpretation of remission in type 2 diabetes (2021) (7)
- Signals and Noise in Drug Safety Analyses (2013) (7)
- Botanicals and cardiometabolic risk: positioning science to address the hype. (2008) (7)
- Treatment of type II diabetes: what options have been added to traditional methods? (1996) (7)
- Determination of furosine in biomedical samples employing an improved hydrolysis and high-performance liquid chromatographic technique. (1991) (7)
- Sotaglif lozin , a Dual SGLT 1 and SGLT 2 Inhibitor , as Adjunct Therapy to Insulin in Type 1 Diabetes (2015) (7)
- Progress to Date for Diabetes Care (2012) (7)
- Clinical Management Strategies for Type 2 Diabetes (2007) (6)
- Erratum. Insulin Access and Affordability Working Group: Conclusions and Recommendations. Diabetes Care 2018;41;1299–1311 (2018) (6)
- Guidelines Versus Guidelines: What's Best for the Patient? (2018) (6)
- A BREIF ORIGINAL CONTRIBUTION (1995) (6)
- Screening native botanicals for bioactivity: an interdisciplinary approach. (2014) (6)
- Titration of inhaled human insulin (Exubera) in a treat-to-target regimen for patients with type 2 diabetes. (2010) (6)
- Augmented transport and metabolism of sex steroids in lymphoid neoplasia in the rat. (1987) (5)
- Modulation of Insulin Action by Botanical Therapeutics (2009) (5)
- Diabetes Care: “Taking It to the Limit One More Time” (2016) (5)
- Rationale for and Strategies to Achieve Glycemic Control (2002) (5)
- Response to Comment on Bergenstal et al. Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring. Diabetes Care 2018;41:2275–2280 (2018) (5)
- Response to Comment on Home et al. Insulin Therapy in People With Type 2 Diabetes: Opportunities and Challenges? Diabetes Care 2014;37:1499–1508 (2014) (5)
- Effects of Artemisia species on de novo lipogenesis in vivo. (2014) (5)
- Status of Diabetes Care: New Challenges, New Concepts, New Measures—Focusing on the Future! (2015) (5)
- Blueberry Bioactives Improve Endothelial Function in Adults with Metabolic Syndrome (2015) (5)
- Statement of Principle (2014) (4)
- Know Diabetes by Heart. (2019) (4)
- American Diabetes Association’s Standards of Care: A Paradigm Shift in the Dissemination of Information (2018) (4)
- Translating “Nondiabetic” A1C Levels to Clinical Practice (2010) (4)
- Potential adverse effects of botanical supplementation in high-fat-fed female mice (2018) (4)
- “New Twist” in Diabetes Care for HbA1c Reporting: “It Takes Two to Tango”! (2012) (4)
- Greater Dose-Ranging Effects on A1C Levels Than on Glucosuria With LX4211, a Dual Inhibitor of Sodium Glucose Transporters SGLT1 and SGLT2, in Type 2 Diabetes on Metformin Monotherapy (2014) (4)
- Health Policy and Diabetes Care: Is It Time to Put Politics Aside? (2015) (4)
- Diabetes Care to Date: “The Hits Just Keep on Coming!” (2013) (4)
- Role of Chromium in Glucose Intolerance, Diabetes, Total Parenteral Nutrition, and Body Composition (2002) (4)
- Status of Diabetes Care: “It Just Doesn’t Get Any Better . . . or Does It?” (2014) (4)
- Introduction to the 5th World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy) (2016) (3)
- Wang ZQ, Yu Y, Zhang XH, Ribnicky D, and Cefalu WT. Ecdysterone enhances muscle insulin signaling by modulating acylcarnitine profile and mitochondrial oxidative phosphorylation complexes in mice fed a high-fat diet. (2011) (3)
- Assessment of long-term immunological and pulmonary safety of inhaled human insulin with up to 24 months of continuous therapy (2008) (3)
- Optimizing Glycemic Control:The Search for Feasible Noninvasive Insulin Delivery Systems (2003) (3)
- The new diabetes inhalers: New tools for the clinician (2007) (3)
- Response to Comment on Cefalu et al. Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum. Diabetes Care 2016;39:1186–1201 (2017) (3)
- Mortality and Glycemic Targets in the Intensive Care Unit: Another Paradigm Shift? (2009) (3)
- Building Momentum: Taking on the Real “Issues” of Diabetes Care! (2015) (3)
- The “Evidence” Is In! It Does Get Better! (2014) (3)
- Guiding Principles for Diabetes Care (2015) (3)
- Glucose control, macro- and microvascular disease, and the Food and Drug Administration: let's keep our eye on the ball. (2008) (3)
- Reevaluation of CMS’ Competitive Bidding Program (2016) (3)
- Perceptions Community Residents Have about Partner Institutions and Clinical Research (2013) (2)
- Short Communication Restrictive Transport of a Lipid-Soluble Peptide (Cyclosporin) Through the Blood- Brain Barrier (1985) (2)
- Role of obesity and body fat distribution in cardiometabolic risk (2007) (2)
- Author reply: Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. (2010) (2)
- Insulin physiology and therapy. Preface. (2012) (2)
- The relationship between obesity and type 2 diabetes—the role of gut factors (2015) (2)
- Insulin resistance and cardiometabolic risk (2007) (2)
- Bariatric surgery: part of the answer to the obesity epidemic. (2006) (2)
- 22. Long-Term Safety and Efficacy of Dapagliflozin in Patients with T2DM and Cardiovascular Disease (106-OR) (2015) (2)
- Abstract 10606: Blood Pressure Reduction With Dapagliflozin in Patients With Type 2 Diabetes and Cardiovascular Disease (2013) (2)
- Comprar Atlas of Cardiometabolic Risk | William T. Cefalu | 9780849370533 | Informa Healthcare (2007) (2)
- Classification and evolution of increased cardiometabolic risk states (2007) (2)
- Novel Communications in Diabetes: Another Small but Significant Step for Diabetes Care (2013) (2)
- Global Call for Free Academic Movement for International Dialogue (2012) (2)
- The Right Diabetes Medication for the Right Patient for the Right Outcome: Can a Network Meta-analysis Help Us Decide? (2020) (2)
- Alternative approaches to subcutaneous insulin injections (2002) (2)
- Chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle glut-4 translocation in obese, hyperinsulinemic rats (2000) (2)
- Non-traditional risk factors of cardiometabolic risk (2007) (2)
- George A. Bray, MD: Progress in Obesity—Multidisciplinary Research, Multidimensional Man (2016) (1)
- A Real-World Evaluation of the Association between Cardiovascular Outcomes and T2D Therapy (2018) (1)
- Diabetes Care: “Lagniappe” and “Seeing Is Believing”! (2016) (1)
- Recognition and Assessment of Insulin Resistance (2002) (1)
- Quercetin and red onion extract attenuate high fat diet‐induced insulin resistance while increasing energy expenditure and skeletal muscle mitochondrial number despite a decrease in Pgc1a (829.1) (2014) (1)
- Traditional metabolic risk factors (2007) (1)
- Efficacy and safety of inhaled insulin therapy. Authors' reply (2006) (1)
- Extramyocellular adipose tissue in type 2 diabetes. (2009) (1)
- Obesity and Its Treatment in Type 2 Diabetes (2008) (1)
- Opportunities for Research for COVID-19 in the Mission of NIDDK (2020) (1)
- Primary Prevention of Type 2 Diabetes: There Are No Simple Solutions! (2009) (1)
- A Critical Evaluation of Glycated Protein Parameters in Advanced Nephropathy: AM atter of Life or Death Time to dispense with the hemoglobin A1C in end-stage kidney (2012) (1)
- Abstract 10677: Dapagliflozin in Patients With Type 2 Diabetes and Established Cardiovascular Disease: Hypotension and Volume-related Safety (2013) (1)
- Erratum. George A. Bray, MD: Progress in Obesity—Multidisciplinary Research, Multidimensional Man. Diabetes Care 2016;39:1481–1485 (2017) (1)
- Pre-meal inhaled insulin treatment is an effective alternative to regular meal-related insulin injections in patients with type 1 diabetes (2000) (1)
- Diabetes: HOME reveals new data on a cornerstone of treatment (2009) (1)
- Statement of principle. (2014) (1)
- Overcoming the barriers for achieving standards of diabetes care: the formation of CADRE. (2003) (1)
- An extract of artemisia drancunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation (2013) (1)
- Adenovirus type 36 reduces fatty acid oxidation by increasing Cidec/FSP27 (2009) (0)
- Racial Differences in the Relationship of Birth Weight to the Metabolic Syndrome in Pre-pubertal Youth: 772 (2007) (0)
- Evaluation of botanicals for improving human health 1 – 4 (2008) (0)
- Clinical outcomes of patients with cardiometabolic risk factors (2007) (0)
- Reducing the glycemic load of mixed meals reduces postprandial glycemia and insulinemia over the entire day but does not affect satiety (2012) (0)
- Lifestyle Approaches to the Metabolic Syndrome (2013) (0)
- Book Review (2001) (0)
- Partial remission of diabetes mellitus (type 1 or type 2) (2020) (0)
- Reduced membrane transport of long chain fatty acid (LCFA) in the muscle of fat, insulin resistant rats (JCR:LA-cp): A mechanism that may contribute to obesity (2000) (0)
- Consensus Reports (2011) (0)
- SMN-targeted therapeutics for spinal muscular atrophy: are we SMArt enough yet? (2014) (0)
- Aging and Exercise Creatine ( methyl -d 3 ) dilution in urine for estimation of total body skeletal muscle mass: accuracy and variability vs. MRI and DXA (2017) (0)
- Efficacy and Safety of Inhaled Insulin Therapy (2006) (0)
- Glycemic response related more strongly to glycemic index (GI) of diet than to carbohydrate (CHO) level (2009) (0)
- Efficiency in Mice MetabolicReduces Physical Endurance and Transporter ) i / P 2 + SLC 25 A 25 ( ATP-Mg Inactivation of the Mitochondrial Carrier Bioenergetics : (2011) (0)
- Glycohemoglobin MeasuredbyAutomatedAffinityHPLCCorrelateswithBoth Short-Termand Long-TermAntecedentGlycemia (1994) (0)
- Botanicals and translational medicine: a paradigm shift in research approach. (2014) (0)
- Protein tyrosine phosphatase 1B gene expression in skeletal muscle is linked to metabolic flexibility in African Americans (2009) (0)
- reducing adiposity or dietary fat Template to improve glycemic control without (2011) (0)
- Effects of a Botanical Extract from Artemisia dracunculus L. on Insulin Sensitivity of Human Skeletal Muscle Cell Cultures (2011) (0)
- Body Mass Index and the Risk of All-Cause Mortality Among Patients With Type 2 Diabetes Mellitus Epidemiology and Prevention (2014) (0)
- Alcohol accentuates simian immunodeficiency virus‐induced alterations in the skeletal muscle milieu contributing to impaired satellite cell myogenic differentiation (732.5) (2014) (0)
- Diabetes Care: Change Is Constant, Part 2 (2017) (0)
- The Clinical Application of Inhaled Insulin (2007) (0)
- Bioactives of Artemisia dracunculus L. ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture (LB333) (2014) (0)
- short-term creatine monohydrate supplementation content in skeletal muscle of young men following Global and targeted gene expression and protein (2015) (0)
- ACE inhibitors enhance insulin signaling by reducing PTP 1B protein abundance and its activity in primary skeletal muscle cells from Type 2 diabetes (2006) (0)
- Blood Pressure Control Increases Coronary Heart Disease Risk Among Diabetic Patients (2013) (0)
- Potential adverse effects of botanical supplementation in high-fat-fed female mice (2018) (0)
- Insulin Sensitizers Versus Secretagogues as First‐Line Therapy for Diabetes: Rationale for Clinical Choice (2011) (0)
- Noninvasive Insulin-Delivery Systems: Options and Progress to Date (2002) (0)
- Statement of Principle (1990) (0)
- PTP1B: A molecular mediator of leptin resistance. (2007) (0)
- Assessment of long-term immunological and pulmonary safety of inhaled human insulin with up to 24 months of continuous therapy. (2008) (0)
- Multidisciplinary Interventions (2008) (0)
- Quercetin causes dose‐related increases in energy expenditure and PGC1α in muscle of C57BL/6J mice (2010) (0)
- Increased nonenzymatically glycosylated proteins in the vitreous humor of diabetic animals. (1999) (0)
- POSTERS (2007) (0)
- Identifying Trends in Undiagnosed Diabetes in U.S. Adults (2018) (0)
- The “Evidence” Is In! It Does Get Better! (2014) (0)
- Precision medicine in diabetes: a consensus report from the ADA and EASD (2020) (0)
- Technologies and experimental approaches in the NIH Botanical Research Centers (2008) (0)
- Erratum (1997) (0)
- Modulation of PPAR γ Stability and Transcriptional Activity in Adipocytes by Resveratrol (2008) (0)
- Complete remission of diabetes mellitus (type 1 or type 2) (2020) (0)
- The Alarming and Rising Costs of DiabetesandPrediabetes:ACallfor (2014) (0)
- Evaluation of Treatment Persistence in Individuals with Type 2 Diabetes in a Real-World Setting (2018) (0)
- Abstract 06: Body Mass Index And The Risk Of All-cause Mortality Among Patients With Type 2 Diabetes (2014) (0)
- Managing cardiometabolic risk – a brief review (2007) (0)
- Botanicals and the metabolic syndrome 1 – 4 (2008) (0)
- Is an Indispensable Tool in Evidence Synthesis (2013) (0)
- Comprar Insulin Therapy, An Issue of Endocrinology and Metabolism Clinics | William T. Cefalu | 9781455738571 | Saunders (2012) (0)
- The Effect of Formulation on the Bioactivity of Artemisia Preparations for Metabolic Syndrome (2013) (0)
- COVID-19 and Rising Incidence of Diabetes: Despite Evolving Data, an Enigma Still to Be Solved (2023) (0)
- Physiologic systems regulating energy balance, including the endocannabinoid system (2007) (0)
- Pharmacologic Agents and Nutritional Supplements in the Treatment of Obesity (2006) (0)
- Race, pregravid BMI and gestational weight gain determine placental fatty acid transfer (2013) (0)
- Remission of diabetes mellitus (type 1 or type 2) (2020) (0)
- Response to Comment on Riddle et al. Diabetes Care Editors’ Expert Forum 2018: Managing Big Data for Diabetes Research and Care. Diabetes Care 2019;42:1136–1146 (2019) (0)
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