Wojciech J. Stec

Wojciech J. Stec's AcademicInfluence.com Rankings

Wojciech J. Stec

Chemistry

#4093

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#5154

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Physical Chemistry

#606

World Rank

#659

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chemistry Degrees

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Chemistry

Wojciech J. Stec's Degrees

PhD Chemistry University of California, Berkeley
Masters Chemistry University of Warsaw
Bachelors Chemistry University of Warsaw

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Wojciech J. Stec's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inner-orbital binding-energy shifts of antimony and bismuth compounds (1973) (341)
Inner-orbital photoelectron spectroscopy of the alkali metal halides, perchlorates, phosphates, and pyrophosphates (1973) (297)
Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides (1984) (232)
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer (2019) (203)
Competitive cAMP antagonists for cAMP-receptor proteins. (1984) (188)
Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication. (2005) (177)
Novel route to oligo(deoxyribonucleoside phosphorothioates). Stereocontrolled synthesis of P-chiral oligo(deoxyribonucleoside phosphorothioates). (1991) (115)
Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases. (1984) (111)
Recent advances in the elucidation of the mechanisms of action of ribozymes. (2001) (108)
Diastereomers of Nucleoside 3'-O-(2-Thio-1,3,2-oxathia(selena)phospholanes): Building Blocks for Stereocontrolled Synthesis of Oligo(nucleoside phosphorothioate)s (1995) (105)
Measured binding energy shifts of "3p" and "3d" electrons in arsenic compounds (1972) (105)
Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3',5'-phosphorothioate. (1983) (94)
Interaction of cAMP derivatives with the 'stable' cAMP-binding site in the cAMP-dependent protein kinase type I. (1982) (91)
Deoxyribonucleoside 3‘-O-(2-Thio- and 2-Oxo-“spiro”-4,4-pentamethylene-1,3,2-oxathiaphospholane)s: Monomers for Stereocontrolled Synthesis of Oligo(deoxyribonucleoside phosphorothioate)s and Chimeric PS/PO Oligonucleotides§ (1998) (89)
Reversed-phase high-performance liquid chromatographic separation of diastereomeric phosphorothioate analogues of oligodeoxyribonucleotides and other backbone-modified congeners of DNA. (1985) (88)
Stereocontrolled Synthesis of Oligo(nucleoside phosphorothioate)s (1994) (84)
Stability of stereoregular oligo(nucleoside phosphorothioate)s in human plasma: diastereoselectivity of plasma 3'-exonuclease. (1997) (82)
Stereodifferentiation--the effect of P chirality of oligo(nucleoside phosphorothioates) on the activity of bacterial RNase H. (1995) (78)
Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent. (1995) (76)
Wadsworth-Emmons reaction revisited (1983) (74)
Specificity of cyclic GMP activation of a multi-substrate cyclic nucleotide phosphodiesterase from rat liver. (2005) (74)
An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase. (2009) (74)
.pi.-Bond feedback interpreted from the binding energy of the "2p" electrons of phosphorus (1971) (68)
Bis(O,O-diisopropoxy phosphinothioyl) disulfide - a highly efficient sulfurizing reagent for cost-effective synthesis of oligo(nucleoside phosphorothioate)s (1993) (67)
Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates. (1986) (62)
Stereospecific synthesis of adenosine 3′,5′-(SP)- and -(RP)-cyclic phosphorothioates (cAMPS) (1979) (59)
Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid. (1990) (58)
Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10–23 (2007) (56)
Mechanisms of coupling between DNA recognition specificity and catalysis in EcoRI endonuclease. (2004) (54)
Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase. (2000) (53)
Stereochemistry of hydrolysis of adenosine 3':5'-cyclic phosphorothioate by the cyclic phosphodiesterase from beef heart. (1979) (52)
Stereochemical studies of the formation of chiral internucleotide linkages by phosphoramidite coupling in the synthesis of oligodeoxyribonucleotides (1985) (52)
Stereodefined phosphorothioate analogues of DNA: relative thermodynamic stability of the model PS-DNA/DNA and PS-DNA/RNA complexes. (2002) (51)
Oxidation in organophosphorus chemistry: Potassium peroxymonosulphate (1999) (50)
Stereoselective interaction with chiral phosphorothioates at the central DNA kink of the EcoRI endonuclease-GAATTC complex. (1992) (50)
DNAzymes to β1 and β3 mRNA Down-regulate Expression of the Targeted Integrins and Inhibit Endothelial Cell Capillary Tube Formation in Fibrin and Matrigel* (2002) (49)
Biochemical, Crystallographic, and Mutagenic Characterization of Hint, the AMP-Lysine Hydrolase, with Novel Substrates and Inhibitors* (2004) (49)
Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine. (1983) (49)
Comparative metabolism of 2-[bis(2-chloroethyl)amino]tetrahydro-2-H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide) and its enantiomers in humans. (1979) (45)
A stereochemical investigation of the hydrolysis of cyclic AMP and the (Sp)-and (Rp)-diastereoisomers of adenosine cyclic 3':5'-phosphorothioate by bovine heart and baker's-yeast cyclic AMP phosphodiesterases. (1982) (45)
The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5'-nucleotidase. (2001) (44)
Application of phosphate-backbone-modified oligonucleotides in the studies on EcoRI endonuclease mechanism of action. (1992) (43)
Drosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms (2013) (42)
Stereochemistry of organophosphorus cyclic compounds—II : Stereospecific synthesis of cis- and trans 2-halogeno-2-oxo-4-methyl-1,3,2-dioxaphosphorinans and their chemical transformations (1973) (42)
A Study of the Synthesis of Optically Active Amines from Prochiral N-Phosphinylimines (1982) (41)
P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides. (2003) (40)
Cyclophosphamide and its congeners (1982) (39)
Negative regulation of Drosophila JAK–STAT signalling by endocytic trafficking (2010) (39)
Stereodependent inhibition of plasminogen activator inhibitor type 1 by phosphorothioate oligonucleotides: proof of sequence specificity in cell culture and in vivo rat experiments. (1997) (39)
Analysis of oligo(deoxynucleoside phosphorothioate)s and their diastereomeric composition. (1995) (39)
A general method for the synthesis of glycerophospholipids (1986) (38)
Investigations on stimulation of lac transcription in vivo in Escherichia coli by cAMP analogues. Biological activities and structure-activity correlations. (1984) (37)
A NEW APPROACH TO THE SYNTHESIS OF PRIMARY AMINES, ISOTHIOCYANATES, AND 1-AMINOALKANEPHOSPHONATES VIA N-PHOSPHINYL ALDOXIMES AND KETOXIMES (1978) (37)
Alkyl phosphotriester modified oligodeoxyribonucleotides. V. Synthesis and absolute configuration of Rp and Sp diastereomers of an ethyl phosphotriester (Et) modified EcoRI recognition sequence, d[GGAA(Et)TTCC]. A synthetic approach to regio- and stereospecific ethylation-interference studies. (1986) (36)
Nucleotide pyrophosphatase/phosphodiesterase 1 is responsible for degradation of antisense phosphorothioate oligonucleotides. (2007) (36)
Synthesis of Oligo(Deoxyribonucleoside Phosphorodithioate)s by the Dithiaphospholane Approach (1995) (35)
A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. (1982) (35)
Drosophila SOCS Proteins (2011) (35)
Preparation of 35S-labeled polyphosphorothioate oligodeoxyribonucleotides by use of hydrogen phosphonate chemistry. (1990) (35)
Organophosphorus compounds of sulfur and selenium. Stereochemistry of oxidation of thiono- and selenophosphoryl compounds with hydrogen peroxide (1976) (34)
Synthesis, separation, and stereochemistry of diastereomeric oligodeoxyribonucleotides having a 5′-terminal internucleotide phosphorothioate linkage (1985) (33)
Inhibition of cAMP-dependent protein kinase by adenosine cyclic 3'-, 5'-phosphorodithioate, a second cAMP antagonist. (1988) (32)
Stereochemistry of organophosphorus cyclic compounds—III : The stereospecific synthesis of cis- and trans-2-N-phenylamino-2-oxo-4-methyl-1,3,2-dioxaphosphorinans (1973) (32)
Stereochemistry of base-catalyzed ring opening of 1,3,2-oxathiaphospholanes. Absolute configuration of 2-{N-[(Rc)-1-(.alpha.-naphthyl)ethyl]amino}-2-thiono-1,3,2-oxathiaphospholanes and O,S-dimethyl N-[(Rc)-1-(.alpha.-naphthyl)ethyl]phosphoramidothioates (1992) (31)
Differences among mechanisms of ribozyme-catalyzed reactions. (2000) (31)
Stereoselective synthesis of P-homochiral oligo(thymidine methanephosphonates). (1988) (31)
Solid-phase synthesis, separation, and stereochemical aspects of P-chiral methane- and 4,4'-dimethoxytriphenylmethanephosphonate analogs of oligodeoxyribonucleotides (1985) (31)
The synthesis of di- and oligo(deoxyribonucleoside phosphorodithioates) by dithiaphospholane method (1992) (31)
Stereochemical course of nucleotidyl transfer catalyzed by bacteriophage T7 induced DNA polymerase. (1982) (30)
Synthesis and absolute configuration of the optically active forms of 2-(bis(2-chloroethyl)amino)-4-methyltetrahydro-2h-1,3,2-oxazaphosphorine 2-oxide (4-methylcyclophosphamide). (1977) (30)
The chemical synthesis of the RP and SP diastereomers of thymidyl(3′-5′)thymidyl 0,0-phosphorothioate (1982) (29)
Chiral phosphorothioates as probes of protein interactions with individual DNA phosphoryl oxygens: essential interactions of EcoRI endonuclease with the phosphate at pGAATTC. (1996) (28)
Synthesis and absolute configuration of P-chiral O-isopropyl oligonucleotide triesters (1985) (28)
STEREOCHEMISTRY OF THE DBU/LICL-ASSISTED NUCLEOPHILIC SUBSTITUTION AT PHOSPHORUS IN NUCLEOSIDE-3'-O-(SE-METHYL METHANEPHOSPHONOSELENOLATE)S (1998) (27)
Effect of RP and SPPhosphorothioate Substitution at the Scissile Site on the Cleavage Activity of Deoxyribozyme 10-23 (2008) (27)
Stereoselectivity in the metabolism of the enantiomers of cyclophosphamide in mice, rats, and rabbits. (1978) (26)
Stereospecific synthesis of (Rp)- and (Sp)-thymidylyl(3′,5′)thymidylyl methanephosphonates (1987) (26)
The role of tumor necrosis factor in the regulation of antigen presentation by human monocytes. (1990) (26)
New approach to preparation of N-acylphosphoramido(thio)(seleno)ates (2004) (26)
Fhit proteins can also recognize substrates other than dinucleoside polyphosphates (2008) (26)
ENANTIOMERIC 2-ANILINO-2-OXO-1,3,2-OXAZAPHOSPHORINANES: SYNTHESIS AND NMR-INVESTIGATION OF THEIR NON-RACEMIC MIXTURES (1995) (26)
Synthesis and absolute configuration assignments of enantiomeric forms of ifosphamide, sulfosphamide, and trofosphamide (1979) (25)
Stereospecific synthesis of thymidine cyclic 3',5'-(Sp)-and (Rp)-phosphorothioates. (1977) (24)
Efficient One-Pot Synthesis of 2'-Deoxyribonucleoside 3'-O- and 5'-O-Phosphorodithioates. (1997) (23)
Anti-sense oligodeoxynucleoside phosphorothioates nonspecifically inhibit invasion of red blood cells by malaria parasites. (1996) (23)
Oxathiaphospholane Method of Stereocontrolled Synthesis of Diribonucleoside 3',5'-Phosphorothioates. (1996) (22)
Ribonucleoside cyclic 3′,5′-phosphoramidates: synthesis, stereochemistry, and conversion into ribonucleoside cyclic 3′,5′-phosphorothioates and -[18O]phosphates (1987) (22)
New synthesis of S(Se)-alkyl phosphorothio(seleno)lates from the corresponding phosphoroanilidates. Stereospecific cleavage of the phosphorus-nitrogen bond in chiral phosphoroanilidates (1976) (22)
Catalytic phosphoryl interactions of topoisomerase IB. (2005) (21)
Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes (2016) (21)
Deoxyribonucleoside 3′-phosphordiamidites as substrates for solidsupported synthesis of oligodeoxyribonucleotides and their phosphorothioate and dna-triester analogues (1987) (21)
Synthesis of Phosphorothioate Oligonucleotides with Stereodefined Phosphorothioate Linkages (2003) (21)
Recent advances in stereocontrolled synthesis of P-chiral analogues of biophosphates (2002) (20)
2'-deoxyribonucleoside 3'-aryl phosphoranilidates: key intermediates in the stereospecific synthesis of 2'-deoxyribonucleoside cyclic 3',5'-phosphorothioates and dinucleoside(3'→5')-phosphorothioates (1984) (20)
31P-15N spin-spin coupling as a probe for the assignment of absolute configuration in RP- and SP-thymidine cyclic 3′,5′-phosphordimethylamidates (1980) (20)
New Stereospecific Method of Synthesis of [Sp]- and [Rp]-Dinucleoside-(3',5') Methanephosphonates (1994) (20)
Antitumor activity of optical isomers of cyclophosphamide, ifosfamide and trofosfamide as compared to clinically used racemates. (1986) (19)
1,3,2-Oxathiaphospholane approach to the synthesis of P-chiral stereodefined analogs of oligonucleotides and biologically relevant nucleoside polyphosphates (2008) (19)
Absolute configuration of the cancerostatic S(--)-cyclophosphamide. (1977) (19)
Synthesis and antitumor activity of analogues of ifosfamide modified in the N-(2-chloroethyl) group. (1988) (19)
DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in fibrin and matrigel. (2002) (18)
Stereochemical Course of Escherichia coli RNase H (2002) (18)
Inhibition by modified oligodeoxynucleotides of the expression of type-1 plasminogen activator inhibitor in human endothelial cells. (1995) (18)
Stereospecific synthesis of cyclic adenosine 3',5'-(SP)-[18O]phosphate (1980) (17)
Transport and metabolism of N6- and C8-substituted analogs of adenosine 3',5'-cyclic monophosphate and adenosine 3'5'-cyclic phosphorothioate by the isolated perfused rat kidney. (1983) (17)
Oxathiaphospholane approach to the synthesis of oligodeoxyribonucleotides containing stereodefined internucleotide phosphoroselenoate function. (2005) (17)
IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis (2016) (17)
Application of deuterium labelling mass spectrometry in a study of the metabolism of the enantiomers of cyclophosphamide. (1977) (17)
Unusual thermal stability of RNA/[RP-PS]-DNA/RNA triplexes containing a homopurine DNA strand. (2007) (17)
Cyclic organophosphorus compounds. II. Some sterically hindered cyclic hypophosphate systems and related compounds (1967) (17)
Cyclic nucleotide specificity of the activator and catalytic sites of a cGMP-stimulated cGMP phosphodiesterase from Dictyostelium discoideum. (1985) (16)
Stabilities of lead(II) complexes formed in aqueous solution with methyl thiophosphate (MeOPS2–), uridine 5'-O-thiomonophosphate (UMPS2–) or adenosine 5'-O-thiomonophosphate (AMPS2–) (2002) (16)
Novel internucleotide 3'-NH-P(CH3)(O)-O-5' linkage. Oligo(deoxyribonucleoside methanephosphonamidates); synthesis, structure and hybridization properties. (1998) (16)
Heteronuclear Spin-Spin Coupling Constants Between Directly Bonded Atoms as a Probe of Configuration at Phosphorus Atom Involved in Diastereoisomeric 4-Methyl-1,3,2-dioxaphosphorinans (1974) (15)
Thiophosphorylation of biologically relevant alcohols by the oxathiaphospholane approach (2002) (15)
Synthesis of nucleoside alpha-thiotriphosphates via an oxathiaphospholane approach. (2005) (15)
Novel cost-effective methanephosphonoanilidothioate approach to the stereoselective synthesis of dinucleoside (3',5')-methanephosphonates. (1997) (15)
The mass spectrometric fragmentation of some diastereoisomeric 4‐methyl‐1,3,2‐dioxaphosphorinanes (1978) (15)
New approach to the synthesis of oligodeoxyribonucleotides modified with phosphorothioates of predetermined sense of P-chirality (2005) (15)
Stereochemistry of rHint1 hydrolase assisted cleavage of P-N bond in nucleoside 5'-O-phosphoramidothioates. (2007) (15)
The First Stereocontrolled Solid-Phase Synthesis of Di-, Tri-, and Tetra[adenosine (2',5') phosphorothioate]s. (1998) (15)
Potassium peroxymonosulfate (oxone)--an efficient oxidizing agent for phosphothio compounds. (1998) (15)
Mechanism of the Chemoselective and Stereoselective Ring Opening of Oxathiaphospholanes: An Ab Initio Study (1997) (14)
Alkylation of thymine with 1,2-dibromoethane (2001) (14)
31P−15N Coupling Constants and 15N/14N Isotope Effects on 31P NMR Chemical Shifts of 2-Phenylamino-2-oxo(-thioxo, -selenoxo)- 4-methyl-1,3,2-dioxaphosphorinanes and Related Compounds (1983) (14)
Diadenylated polyols as new non-isopolar analogues of diadenosine tri- and tetraphosphates (1999) (14)
Tetra-Thymidine Phosphorofluoridates via Tetra-Thymidine Phosphoro-selenoates: Synthesis and Stability (1999) (14)
A novel approach to the biosynthesis of modified nucleosides in the anticodon loops of eukaryotic tRNAs. (1987) (13)
Effect of P‐chirality of oligo(deoxyribonucleoside phosphorothioate)s on the activity of terminal deoxyribonucleotidyl transferase (1998) (13)
Enhanced P-stereodependent stability of complexes formed by phosphorothioate oligonucleotides due to involvement of sulfur as strong hydrogen bond acceptor (2006) (13)
Axial preference of a 2-anilino-substituent in 4-methyl-1,3,2-dioxaphosphorinan (1975) (13)
Adenosine-5'-O-phosphorylated and adenosine-5'-O-phosphorothioylated polyols as strong inhibitors of (symmetrical) and (asymmetrical) dinucleoside tetraphosphatases. (2003) (13)
Antisense oligonucleotides: Stereocontrolled synthesis of phosphorothioate oligonucleotides (1993) (13)
Antisense oligodeoxyribonucleotide against the MLL-LTG19 chimeric transcript inhibits cell growth and induces apoptosis in cells of an infantile leukemia cell line carrying the t(11;19) chromosomal translocation. (1998) (13)
Crystallographic assessment of absolute configuration in 2'-deoxyadenosine cyclic 3',5'-(Rp)-phosphoranilidate. Direct phosphorus-31-nitrogen-15 spin-spin coupling as a probe for configurational assessment (1981) (13)
Efficient inhibition of beta-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes. (2003) (13)
Inhibition of ADP-triggered blood platelet aggregation by diadenosine polyphosphate analogues. (2002) (12)
Di-, tri- and tetra-5'-O-phosphorothioadenosyl substituted polyols as inhibitors of Fhit: Importance of the α-β bridging oxygen and β phosphorus replacement (2001) (12)
Retention of configuration in the action of human plasma 3'-exonuclease on oligo(deoxynucleoside phosphorothioate). A new method for assignment of absolute configuration at phosphorus in isotopomeric deoxyadenosine 5'-O-[(18)O]phosphorothioate. (2002) (12)
Stereoretentive conversion of dialkyl phosphorothioates into [18O]-phosphates (1983) (12)
The synthesis and X-ray structural studies of 2-cholesteryl-2-thio-1,3,2-oxathiaphospholane and 2-cholesteryl-2-thio-1,3,2-dithiaphospholane (1996) (12)
Conjugation of amino acid O-methyl esters with AZT-5′-O-phosphorothioate and phosphorodithioate (2000) (12)
DBU-assisted 1,3,2-oxathiaphospholane ring-opening condensation with selected O-, S-, N- and C-nucleophiles (2004) (12)
Low Incidence along with Low mRNA Levels of EGFRvIII in Prostate and Colorectal Cancers Compared to Glioblastoma (2017) (12)
Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis. (2011) (11)
NEW SYNTHESIS OF S(SE)‐ALKYL PHOSPHOROTHIO(SELENO)LATES FROM THE CORRESPONDING PHOSPHOROANILIDATES. STEREOSPECIFIC CLEAVAGE OF THE PHOSPHORUS‐NITROGEN BOND IN CHIRAL PHOSPHOROANILIDATES (1976) (11)
DNA-Triesters - The Synthesis and Absolute Configuration Assignments at P-Stereogenic Centres (1987) (11)
NMR studies of backbone-alkylated DNA: duplex stability, absolute stereochemistry, and chemical shift anomalies of prototypal isopropyl phosphotriester modified octanucleotides, (Rp,Rp)- and (Sp,Sp)-(d-[GGA(iPr)ATTCC])2 and -(d-[GGAA(iPr)TTCC])2. (1987) (11)
Notizen: Configurational Assignments to 2-X-2-Y-4-methyl-1,3,2-dioxaphosphorinans (1976) (11)
Chemoselective activation of nucleoside 3'-O-methylphosphonothioates with 1,3,5-triazinyl morpholinium salts. (2007) (11)
Backbone-modified oligonucleotides containing a butanediol-1,3 moiety as a 'vicarious segment' for the deoxyribosyl moiety--synthesis and enzyme studies. (1990) (11)
Effects of (Sp)- and (Rp)-adenosine cyclic 3',5'-phosphorothioates on electrolyte excretion by the isolated perfused rat kidney. (1985) (11)
Protic acid catalyzed thiono-thiolo rearrangements of phosphorus esters (1976) (11)
Inner-orbital photoelectron spectroscopy of several pairs of similar phosphorus compounds (1972) (10)
Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope. (2001) (10)
Stereokontrollierte Synthese von Oligonucleosidphosphorothioaten (1994) (10)
An Improved Preparation of Trimethylsilyl Cyanide (1978) (10)
Stereospecific Synthesis of P-Chiral Di(2′-O-Deoxyribonucleoside)methanephosphonates (1991) (10)
APPLICATION OF OXATHIAPHOSPHOLANE METHOD FOR THE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDE 5'-O-CONJUGATES (1998) (10)
Synthesis of 2‘,3‘-Dideoxyribonucleoside-3‘-N-(2-oxo-1,3,2-oxathiaphospholanes) and Their Reactions with 5‘-OH Nucleosides and Fluoride Ion (1999) (10)
The Axial Preference of Fluorine Atom in 2-Fluoro-4-methyl-1,3,2-dioxaphosphorinanyl Ring System (1976) (10)
A novel route to 1-aminoalkylphosphonic acid (1976) (10)
Ab initio investigation on nucleophilic ring opening of 1,3,2-oxathiaphospholane: nucleophilic substitution at phosphorus coupled with pseudorotation (1996) (10)
Effect of phosphorus-hydrogen deuterium substitution on the phosphorus-31 nuclear magnetic resonance spectroscopy of several dialkyl phosphonates (1971) (10)
Inhibition of human immunodeficiency virus type 1 replication by P‐stereodefined oligo(nucleoside phosphorothioate)s in a long‐term infection model (2002) (10)
Base-Dependent Regioselective and P-Stereocontrolled Hydrolysis of Nucleoside 3‘-O-(O-2,4,6-Trimethylbenzoyl Methanephosphonothioate)s (1998) (9)
A new class of dinucleotide analogues. The synthesis of 3′-O-thymidylyl(5′-deoxy-5′-selene-thymidylyl)-Se-phosphoroselenolate, its O-methyl ester and methanephosphonate derivatives. (1994) (9)
Stereocontrolled synthesis of LNA dinucleoside phosphorothioate by the oxathiaphospholane approach. (2001) (9)
Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5'-O-monophosphorothioate and their derivatives - Implication for desulfuration process in the cell. (2014) (9)
N-benzoyl O,O-dialkyl phosphoranilidates: reaction with O- and N-nucleophiles (1991) (9)
Stereochemistry of cleavage of internucleotide bonds by Serratia marcescens endonuclease. (2001) (9)
Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition? (2003) (9)
Phosphorothioate Oligodeoxyribonucleotides Antisense to PAI-1 mRNA Increase Fibrinolysis and Modify Experimental Thrombosis in Rats (1998) (9)
Regulation of PAI-1 Concentration in Platelets by Systemic Administration of Antisense Oligonucleotides to Rats (2001) (9)
The synthesis of P‐chiral optically pure phosphorothioates, phosphorotrithioates, phosphoroselenothioates, methanephosphonothioates, and methylphenylphosphinothioates (1991) (9)
Dithymidylyl-3′,5′-phosphorofluoridates: new synthesis and stability under solvolytic conditions (1995) (9)
The stereochemistry of reaction of P-chiral dialkyl hydrogen phosphorothioates with [18O]-dimethyl sulphoxide (1982) (8)
Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis. (1987) (8)
Significance of Stereochemistry of 3′-Terminal Phosphorothioate-modified Primer in DNA Polymerase-mediated Chain Extension (2008) (8)
Optically Active Selenoxomethylphenylpropylphos‐phoranes and Their Transformations (1971) (8)
Phosphate-Modified Oligonucleotides. The Synthesis, Stereochemistry and ECO Ri Endonuclease Substrate Ability of Decanucleotides d[GGGAATTCCC] Bearing Altered Internucleotide Phosphate Function Between A and A1 (1989) (8)
Reversible oxidation of phosphylthionates and phosphylselenonates with trifluoroacetic anhydride (1990) (8)
Deoxyxylothymidine 3′-O-phosphorothioates: Synthesis, stereochemistry and stereocontrolled incorporation into oligothymidylates (1997) (8)
X-ray and high resolution selenium-77 solid state NMR spectroscopy as complementary probes to structural studies of organophosphorus diselenides. (1998) (8)
Synthesis and assignment of absolute configuration of enantiomeric dicyclohexylammonium 2‐oxo‐2‐thioxo‐1,3,2‐oxathiaphospholanes (1994) (8)
The P‐Stereocontrolled Synthesis of PO/PS‐Chimeric Oligonucleotides by Incorporation of Dinucleoside Phosphorothioates Bearing an O‐4‐Nitrophenyl Phosphorothioate Protecting Group (2005) (8)
SYNTHESIS OF 1‐AMINOALKANEPHOSPHONATES VIA THIOUREIDOALKANEPHOSPHONATES (1978) (8)
The Stereochemistry of P-N Bond Cleavage in the Staudinger -Wittig-type Reaction of 2-Anilido-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine-2-thiones (1978) (7)
Stereochemistry and product distribution in the thiono-thiolo rearrangement of phosphorothioic esters. 4. Role of leaving-group solvation (1981) (7)
Study of phosphorus-sulfur compounds by inner-orbital photoelectron spectroscopy. Thiono-thiolo sulfur (1971) (7)
Nucleoside 3′-O-(2-Oxo-“Spiro”-4.4-Pentamethylene-1.3.2-Oxathiaphospholane)S: Monomers For Stereocontrolled Synthesis Of Oligo(Nucleoside Phosphorothioate/Phosphate)S (1998) (7)
Modulation of plasminogen activator inhibitor type-1 biosynthesis in vitro and in vivo with oligo(nucleoside phosphorothioate)s and related constructs. (1997) (7)
Axial Preference of Methylthio Substituent in Dioxaphosphorinanyl Ring System (1975) (7)
Stereodefined dinucleoside (3′,5′)-propionamidophosphonates and β-cyanoethylphosphonates and their incorporation into modified oligonucleotides (2009) (7)
Cyclic trans-phosphorylation in a homodimer as the predominant mechanism of EGFRvIII action and regulation (2018) (7)
Isolation and identification of a metabolic intermediate in the selective dechloroethylation of one of the four stereoisomers of 4-methylcyclophosphamide. (1978) (7)
STEREOSPECIFIC SYNTHESIS OF CYCLIC ADENOSINE 3′,5′-(SP)-(18O)PHOSPHATE (1980) (7)
Electrophilic catalysis of N-- > 0 phosphyl migration (1991) (7)
Mechanisms of JAK/STAT pathway negative regulation by the short coreceptor Eye Transformer/Latran (2016) (7)
Analogues of Acyclic Nucleosides Derived from Tris-(Hydroxymethyl)Phosphine Oxide or Bis-(Hydroxymethyl)Phosphinic Acid Coupled to DNA Nucleobases (2004) (7)
AN IMPROVED SYNTHESIS OF 6-(O-PHOSPHORYLCHOLINE)HYDROXYHEXANOIC ACID (1991) (6)
Thiono-thiolo rearrangement and solvolysis of the secondary alkyl phosphorothionates. 3 (1981) (6)
Biophosphates and their analogues : synthesis, structure, metabolism, and activity : proceedings of the 2nd International Symposium on Phosphorus Chemistry Directed Towards Biology, Łodz, Poland, 8-12 September 1986 (1987) (6)
Cyclization versus oligomerization of SP- and RP-5′-OH-N4-benzoyl-2′-deoxycytidine-3′-O-(2-thio-4,4-pentamethylene-1,3,2-oxathiaphospholane)s (2006) (6)
Influence of protonic solvents on spin–spin coupling involving phosphorus directly bonded to hydrogen, fluorine, or another phosphorus atom in phosphoryl and thiophosphoryl molecules (1972) (6)
Synthesis of adenosine cyclic 3′,5′-phosphorof)uoridate (camp-f) (1995) (6)
One-Pot Synthesis of Dinucleoside (3′,5′)-Methylphosphonothioates and their Seleno Congeners via the Phosphonotriazolidite Approach (2006) (6)
The cytotoxicity of anti-PAI-1 oligonucleotides and their conjugates. (1999) (6)
Activity of acid deoxyribonuclease towards diastereoisomers of thymidyl 3'-(4-nitrophenyl phosphorothioate). Stereochemistry of transnucleotidylation reaction. (1986) (6)
Activation of Methylphosphonates and Their Thio- and Seleno Congeners with 1,3,5-Triazinyl Morpholinium Salts. Selenono-Selenolo Isomerization (2008) (6)
THE SYNTHESIS OF DITHYMIDINE BORANOPHOSPHATE BY THE OXATHIAPHOSPHOLANE APPROACH (2001) (6)
New approach to the synthesis of nucleoside phosphorothioates (1977) (6)
STEREOSPECIFIC SYNTHESIS OF CHIRAL METABOLITES OF IFOSFAMIDE AND THEIR DETERMINATION IN THE URINE (1983) (6)
2'-OMe-Uridin-3'-yl (3',5')-5'-O-(2'-OMe-Cytidine)-methanephosphonothioates - new building blocks for synthesis of chimeric oligonucleotides (2004) (5)
Studies on the mechanism of electron impact induced SH radical loss from the diastereoisomeric 2-dimethylamino-2-thiono-4-methyl-1,3,2-dioxaphosphorinanes (1980) (5)
Formation of diastereoisomeric derivatives from the enantiomers of the antitumour agent cyclophosphamide by reaction with 1-phenethyl alcohol, and their separation by thin-layer chromatography (1979) (5)
Synthesis of a dialkyl phosporoisocyanidate (1974) (5)
THE MOLECULAR STRUCTURE OF CIS-2-t-BUTYLAMINO-2-SELENO-4,4,6-TRIMETHYL-1,3,2-DIOXAPHOSPHORINANE C10H22NO2PSe, AN EXAMPLE OF THE TWIST-BOAT CONFORMATION (1978) (5)
Internalization of oligodeoxynucleotide antisense to type-1 plasminogen activator inhibitor mRNA in endothelial cells: a three-dimensional reconstruction by confocal microscopy. (1996) (5)
Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification. (1999) (5)
Stereochemistry of the reaction of ribonucleoside cyclic 3′,5′‐phosphorothioates with oxiranes (1991) (5)
An oxathiaphospholane approach to one-pot phosphorothioylation of isoprenoid alcohols. (2004) (5)
Notizen: Stereochemistry of Oxidation of Thiophosphoryl Group in 1,3,2-Dioxaphosphorinans (1971) (5)
A new method of phosphorus-selenium bond cleavage. Stereocontrolled synthesis of P-chiral phosphoric-trifluoroacetic anhydrides (1992) (5)
Diastereomerically pure nucleoside-5'-O-(2-thio-4,4-pentamethylene-1,3,2-oxathiaphospholane)s--substrates for synthesis of P-chiral derivatives of nucleoside-5'-O-phosphorothioates. (2011) (5)
Oxathiaphospholane Approach to the Synthesis of Conjugates of Amino Acids Methyl Esters with Nucleosides (2002) (5)
The metabolism and antitumour activity of the enantiomers of cis- and trans-4-methylcyclophosphamide. (1977) (5)
Stereospecific synthesis of P-chiral analogs of oligonucleotides. (1993) (5)
REMOTE CONTROL OF DIASTEREOSELECTIVITY OF DN-ASE II AND ENDONUCLEASE ECO RI TOWARDS PHOSPHOROTHIOATE ANALOGUES OF OLIGONUCLEOTIDES (1986) (5)
Studies on enzymatic hydrolysis of thymidin-3′-yl thymidin-5′-yl phosphorofluoridates and the corresponding phosphorothiofluoridates (1999) (5)
Stereoselective formation of a P-P bond in the reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with O,O-dialkyl H-phosphonates and H-thiophosphonates. (2010) (5)
Oligo(nucleoside Phosphorothioate)s (1998) (5)
THE SYNTHESIS OF THE OPTICAL ISOMERS OF 2-(2-CHLOROETHYLAMINO)-3-(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE (ISOPHOSPHAMIDE) (1978) (4)
P-Methyl-P-phenylpropylphosphine selenide (1977) (4)
The synthesis of 5′-O-DMT-thymidine 3′-O-(2-THIO-1,3,2-oxaselenaphospholane) and its possible application in stereocontrolled synthesis of oligo(nucleoside phosphorothioate)s (1994) (4)
Oligomeric building block approach to the synthesis of diastereomerically pure pentathymidine 3',5'-methanephosphonates. (2000) (4)
REACTION OF CARBONYL ISOTHIO(SELENO)CYANATES WITH TRIVALENT PHOSPHORUS ESTERS (1975) (4)
Deselenization of dialkyl phosphoroisoselenocyanatidite (1975) (4)
Some aspects of the electron impact induced fragmentation of diastereoisomeric thymidine cyclic 3′,5′-phosphoranilidothioates (1980) (4)
Assignment of cis-trans Geometry in Diastereomeric 2-Benzyl-4-methyl-1,3,2-dioxaphosphorinans and their 2-Oxo- and 2-Seleno-Derivatives (1975) (4)
High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits (2018) (4)
Reactivity of nucleoside 5′‐O‐phosphates, ‐phosphorothioates, ‐methanephosphonates, and ‐methanephosphonothioates toward activated xylonucleosides (1999) (4)
Stereochemistry of P-N bond cleavage. First crystal and structural assignment in cyclic phosphoramidofluoridates (1985) (4)
X-Ray-Diffraction Study and Determination of Absolute Configuration of the Anticancer Drug S(–) Cyclophosphamide (Endoxan, Cytoxan, NSC-26271) (1977) (4)
SYNTHESIS OF DIALKYL PHOSPHOROCYANIDITES. AXIAL PREFERENCE OF THE PHOSPHORUS-CYANO GROUP IN THE 1,3,2-DIOXAPHOSPHORINANE RING SYSTEM (1975) (4)
The α-thio and/or β-γ-hypophosphate analogs of ATP as cofactors of T4 DNA ligase. (2016) (4)
Synthesis of 4-nitrophenyl esters of thymidine 3′-phosphate and 3′-phosphorothioate using a new phosphorylating agent (1980) (4)
Synthesis and Structural Studies of SP and RP Diastereomers of Deoxyxylothymidyl-3′-O-acetylthymidyl (3′,5′)-O-(2-Cyanoethyl)phosphorothioate in Solution and in the Solid State (2001) (4)
(S)-(−)-Bromofosfamide (CBM-11): synthesis and antitumor activity and toxicity in mice (2001) (4)
Stereoretentive conversion of cyclic phosphorothioates into [18O]phosphates using [18O]chloral (1984) (4)
Reinvestigation of the reaction between sodium diethyl phosphite and diethyl phosphorochloridate. Evidence for a SET process in the formation of a direct P(IV)P(IV) bond (2002) (4)
Bis(hydroxymethyl)phosphinic acid analogues of acyclic nucleosides; synthesis and incorporation into short DNA oligomers (2002) (4)
Nuclear magnetic resonance coupling constants for a bis(dioxaphosphorinanyl) (1970) (3)
Stereochemical Analysis of Diastereomeric 1,3-bis(Adenosine-5′-O-phosphorothioyl)glycerols (2003) (3)
Dinucleoside (5′ → 3′)-O,S-Phosphorodithioates - New Class of Dinucleotide Analogues (1996) (3)
The effect of divalent cations on the catalytic activity of the human plasma 3′-exonuclease (2010) (3)
Selenium-Derivatized Oligonucleotides (2008) (3)
Stereocontrolled Synthesis of Oligo(nucleosidephosphorothioate)s (1994) (3)
Phosphonocysteine and Phosphonohomocysteine; Synthesis and Isolation (1983) (3)
Stereochemical aspects of the reaction of dialkyl phosphates with amine in the presence of triphenylphospine and carbon tetrachloride (1985) (3)
Fast atom bombardment mass spectra ofO-isopropyl oligodeoxyribonucleotide triesters (1985) (3)
Modulation of beta-secretase gene expression by action of catalytic nucleic acids. (2002) (3)
Electron‐impact‐induced rearrangement of organic hypophosphates (1975) (3)
Novel approach to the synthesis of isotopomeric monoalkyl [16O,17O,18O]phosphates. The stereospecific one-pot conversion of (RP)-thymidine 3′-(4-nitrophenyl)phosphorothioate into (RP)-thymidine 3′-[16O,17O,18O]phosphate (1987) (3)
New P-Chiral Phosphates, Phosphorothioates and Phosphoroselenothioates (1987) (3)
Synthesis and reactivity of dithymidylyl-3',5''-phosphorothiofluoridates (1996) (3)
Stereochemical Course of Escherichia coli RNase H. (2003) (3)
Crystal and molecular structures of isomeric 2‐morpholino‐2‐thiono‐4‐methyl‐1,3,2‐dioxaphosphinane and 2‐morpholino‐2‐oxo‐4‐methyl‐1,3,2‐dioxaphosphinane (1998) (3)
Novel nucleic acid analogs with a chimeric phosphinate / phosphate backbone; synthesis and biophysical properties (2004) (3)
Synthesis and cis-trans-geometry assignment in diastereoisomeric 2-t-butylamino-4-methyl-1,3,2-dioxaphosphorinans and their 2-seleno derivatives (1975) (2)
Notizen: Inhibitor-Effekt von BF3 auf die Umlagerung von / Inhibitory Effect of BF3 on the Rearrangement of (1976) (2)
Nucleophilic N1 → N3 Rearrangement of 5′-O-Trityl-O2,3′-Cycloanhydrothymidine (2000) (2)
Assignment of Absolute Configuration at Phosphorus in Dithymidylyl(3′,5′)phosphormorpholidates and -Phosphormorpholidothioates (1991) (2)
Acyclic analogs of nucleosides based on tris(hydroxymethyl)phosphine oxide: synthesis and incorporation into short DNA oligomers (2015) (2)
THIONO‐THIOLO REARRANGEMENT AND SOLVOLYSIS OF THE SECONDARY ALKYL PHOSPHOROTHIONATES. 3 (1981) (2)
Stereoretentive conversion of dialkyl [18O]-phosphoranilidates into dialkyl hydrogen [18O]-phosphates (1985) (2)
Fast atom bombardment mass spectra of O‐isopropyl oligodeoxyribonucleotide triesters (1985) (2)
Notizen: Volatile Complexes of Trialkyl Phosphates and Alkylphosphonates with Protic Acids (1970) (2)
Direct transformation of ribonucleoside cyclic 3′,5′-phosphorothioates into cyclic 2′,3′-phosphates (1985) (2)
The synthesis of unsymmetrical S1-(3′-O-thymidine-O-methanephosphonyl)-S2-p-nitrophenyl disulfides and their reactions with triphenylphosphine (2000) (2)
Structure of 5,5-dimethyl-2-ethylamino-1,3,2-dioxaphosphorinane 2-selenide (1986) (2)
The synthesis, X-ray and solid state NMR studies of2-N,N-diisopropylamino-1,3,2λ5-oxaselenaphospholane-2-selone (1997) (2)
STEREOCHEMISTRY OF PHOSPHORUS-NITROGEN BOND CLEAVAGE. FIRST CRYSTAL AND STRUCTURAL ASSIGNMENT IN CYCLIC PHOSPHORAMIDOFLUORIDATES (1985) (2)
Novel method of synthesis of oligo(deoxyribonucleoside phosphorothioates). (1991) (2)
Nucleoside 3′‐O‐(2‐oxo‐“spiro”‐4.4‐Pentamethylene‐1.3.2‐oxathiaphospholane)s: Monomers for Stereocontrolled Synthesis of Oligo(Nucleoside Phosphorothioate/Phosphate)s. (1999) (2)
Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe (2004) (2)
Synthesis, biochemical and biological studies on oligonucleotides bearing a lipophilic dimethoxytrityl group. (1998) (2)
New Approach to the Synthesis of Oligo(nucleoside methanephosphonate)s1 (1996) (2)
Stereochemistry of thiono-thiolo rearrangement of phosphorothioic esters. 2 (1979) (2)
Synthesis and Chemical and Enzymatic Reactivity of Thymidine 3′‐O‐ and 5′‐O‐Phosphorofluoridothioates. (1998) (2)
Synthesis of P-enantiomeric deoxyadenosine cyclic 3, 5-phosphorothioates (1978) (2)
THE SYNTHESIS OF ENANTIOMERIC CYCLOPHOSPHAMIDES (1976) (2)
Conformation of Sterically Hindered 4-Methyl-2-oxo-2-trityl-1,3,2-dioxaphosphorinane in the Solid State and the Solution (2011) (2)
Negative regulation of Drosophila JAK–STAT signalling by endocytic trafficking (2010) (1)
Efficient One‐Pot Synthesis of 2′‐Deoxyribonucleoside 3′‐O‐ and 5′‐O‐ Phosphorodithioates (1997) (1)
Effect of Modifications on the Intracellular Activity of a DNA Enzyme (2004) (1)
One-pot synthesis of nucleoside 3′-O-(S-phenyl methanephosphonothioates) (2000) (1)
Oxathiaphospholane Approach to the Synthesis of Nucleoside Methanephosphonothioates (2004) (1)
Bis(O,O-diisopropoxyphosphinothioyl) Disulfide. A Highly Efficient Sulfurizing Reagent for Cost-Effective Synthesis of Oligo(Nucleoside Phosphorothioate)s. (1994) (1)
New method of preparation of monomers for large scale stereocontrolled synthesis of dinucleoside (3',5') methanephosphonates (1996) (1)
Synthesis Of Asymmetric S, S, S-Trialkyl Phosphorotrithioates (1977) (1)
New examples of mixed seleno-sulfides; reactions with triphenylphosphine. (2002) (1)
The synthesis of di- and oligo-nucleotides containing a phosphorodithioate internucleotide linkage with one of the sulfur atoms in a 5'-bridging position. (2009) (1)
NOVEL OBSERVATION ON BASE-CATALYZED BENZOYLATION OF DIALKYL PHOSPHORANILIDATES (1987) (1)
Synthesis and interaction with thymidylate synthase of 5'-dithiophosphate and 5'-fluorothiophosphate of thymidine. (1998) (1)
Midinfrared vibrational circular dichroism studies of cyclophosphamide and its congeners (1982) (1)
Alkoxyphosphonium salt intermediates in the thiono-thiolo rearrangement of phosphylthionates in protic acid media (1988) (1)
ABSOLUTE CONFIGURATION OF THE CANCEROSTATIC S(-)-CYCLOPHOSPHAMIDE (1977) (1)
Synthesis of Some Substituted 1,3,2-Oxazaphosphorinanes (1987) (1)
The synthesis of enantiomers of 4-ketocyclophosphamide (1981) (1)
1,3,2-Oxathiaphospholane Approach to the Synthesis of P-Chiral Stereodefined Analogues of Oligonucleotides and Biologically Relevant Nucleoside Polyphosphates (2009) (1)
Antibodies to recombinant fragment 212-276 of protein C specifically recognize the intact human molecule. (1993) (1)
SYNTHESIS OF ENANTIOMERS OF 1-AMINO-2-PHENYLETHYLPHOSPHONIC ACID (1978) (1)
The axial/equatorial preference of the diphenylphosphino group bonded to the phosphorus of a 2‐oxo‐1,3,2‐dioxaphosphorinanyl ring (1977) (1)
SYNTHESIS OF 5′-O-(R,S)-(1-AMINOETHANE-1-PHOSPHONYL)URIDINE AND -ADENOSINE (1979) (1)
Stereochemistry of Dbu-Assisted Reaction of Nucleoside 3'-O-(2-Thiono-1.3.2-Oxathiaphospholanes) with 5'-Hydroxynucleosides (1996) (1)
New Stereospecific Method of Synthesis of (Sp)- and (Rp)-Dinucleoside-( 3′,5′) Methanephosphonates. (1995) (1)
Synthesis and an Antiviral Activity Evaluation of Nucleoside 5′-O-(N-acyl) Phosphoramidates (2011) (1)
Stereospecific synthesis of adenosine cyclic 3′,5′-RP- and SP-phosphoro-[35S]thioates (1984) (1)
A simple procedure for synthesis of diastereoisomers of thymidine cyclic 3',5'-phosphate derivatives. (1987) (1)
Nucleoside-O-(2-Thiono-1,3,2-Oxathiaphospholane)S-Versatile Tools in the Synthesis of Oligonucleotide Analogues (1999) (1)
A novel class of DNA analogs bearing 5'-C-phosphonothymidine units: synthesis and physicochemical and biochemical properties. (2006) (1)
Deoxyxylothymidine 3′-O-Phosphorothioates: Synthesis, Stereochemistry and Stereocontrolled Incorporation into Oligothymidylates. (1998) (1)
A New Method of P-Se Bond Cleavage: Stereocontrolled Synthesis of P- Chiral Phosphoric-Trifluoroacetic Anhydrides. (1993) (1)
STEREOCHEMISTRY OF OXIDATION OF P(III) COMPOUNDS WITH AMINE N-OXIDES. EQUATORIAL PREFERENCE OF N,N-DIMETHYLAMINO GROUP IN 4-METHYL-1,3,2-DIOXAPHOSPHORINANYL RING SYSTEM (1973) (1)
Antisense oligonucleotides to PAI-1 mRNA as potential agents for therapeutic intervention in cardiovascular diseases (1996) (1)
DBU‐Assisted 1,3,2‐Oxathiaphospholane Ring‐Opening Condensation with Selected O‐, S‐, N‐ and C‐Nucleophiles. (2004) (1)
31P NMR Kinetic Studies of Alkylation Chemistry of N,N′-Bis(2-Chloroethyl)Phosphordiamidic Acid and Its Congeners (1990) (1)
A General Method for the Synthesis of Glycerophospholipids. (1987) (1)
STEREOCHEMISTRY OF THIOCYANO-ISOTHIOCYANO REARRANGEMENT=P(O)SCN-=P(O)NCS IN 2-OXO-4-METHYL-1,3,2-DIOXAPHOSPHORINANYL RING SYSTEM (1975) (0)
Ribonucleoside Cyclic 3′, 5′-Phosphoramidates: Synthesis, Stereochemistry, and Conversion into Ribonucleoside Cyclic 3′,5′-Phosphorothioates and -(18O)Phosphates. (1987) (0)
P-Chiral Dialkyl (18O) Phosphates and Monoalkyl (16O,17O,18O) Phosphates. Stereospecific Reaction of Phosphorothioates with Styrene (18O) Oxide (1988) (0)
STEREORETENTIVE CONVERSION OF DIALKYL (18O)-PHOSPHORANILIDATES INTO DIALKYL HYDROGEN (18O)-PHOSPHATES (1985) (0)
Oligomeric Building Block Approach to the Synthesis of Diastereomerically Pure Pentathymidine 3′,5′-Methanephosphonates. (2000) (0)
Potassium Peroxymonosulfate (Oxone) — An Efficient Oxidizing Agent for Phosphothio Compounds. (1999) (0)
Stereodifforentiation-the effect of P chirality of oligo ( nucleoside phosphorothioates ) on the activity of bacterial RNase (0)
Erratum: Protic acid catalyzed thiono-thiolo rearrangements of phosphorus esters (Journal of Organic Chemistry (1976) 41, (1291)) (1976) (0)
New P-Chiral Phosphates, Phosphorothioates, and Phosphoroselenothiates. (1987) (0)
Synthesis of 2′,3′-Dideoxyribonucleoside-3′-N-(2-oxo-1,3,2-oxathiaphospholanes) and Their Reactions with 5′-OH Nucleosides and Fluoride Ion. (1999) (0)
Reversible Oxidation of Phosphylthionates (I) and Phosphylselenonates ( III) with Trifluoroacetic Anhydride. (2010) (0)
Conformation of Diastereomers of Adenosine Cyclic 3′, 5′-Phosphorothioate (1990) (0)
Communications to the Editor Crystallographic Assessment of Absolute Configuration in 2'-Deoxyadenosine Cyclic 3',5'-( R,)-Phosphoranilidate. Direct 31P-15N Spin-Spin Coupling as a Probe for Configurational Assessment (1981) (0)
High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C84A mutant from rabbit complexed with adenosine (2010) (0)
HETERONUCLEAR SPIN-SPIN COUPLING CONSTANTS BETWEEN DIRECTLY BONDED ATOMS AS A PROBE OF CONFIGURATION AT PHOSPHORUS ATOM INVOLVED IN DIASTEREOMERIC 4-METHYL-1,3,2-DIOXAPHOSPHORINANS (1974) (0)
ORGANOPHOSPHORUS COMPOUNDS PART 185, ORGANOPHOSPHORUS COMPOUNDS OF SULPHUR AND SELENIUM PART 1, STEREOCHEMISTRY OF SILVER-ION PROMOTED SOLVOLYSIS OF SOME HALOGENOANHYDRIDES AND THIOLOESTERS OF ORGANOPHOSPHORUS ACIDS (1974) (0)
Oxathiaphospholane Method of Stereocontrolled Synthesis of Diribonucleoside 3′,5′-Phosphorothioates. (1997) (0)
THE STEREOCHEMISTRY OF P-N BOND CLEAVAGE IN THE STAUDINGEWR-WITTIG-TYPE REACTION OF 2-ANILIDO-3,4-DIMETHYL-5-PHENYL-1,3,2-OXAZAPHOSPHOLIDINE-2-THIONES (1978) (0)
Synthesis of Dialkyl Phosphoroselenocyanatidates and Their Rearrangement to Dialkyl Phosphoroiso-selenocyanatidates (1978) (0)
Thermal Intramolecular Isomerization of 2-Isoselenocyanato-5,5- dimethyl-1,3,2-dioxaphosphorinane into 2-Cyano-2-selenoxo-5,5-dimethyl- 1,3,2-dioxaphosphorinane. (1991) (0)
P‐Methyl‐P‐phenylpropylphosphine selenide. Correction of a printer's error (1977) (0)
Perspectives for medicinal applications of synthetic oligonucleotides: antisense technology (1996) (0)
An Improved Synthesis of 6‐(O‐Phosphorylcholine)hydroxyhexanoic Acid. (1991) (0)
Re-investigated high resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) from rabbit complexed with adenosine (2010) (0)
INHIBITION OF THE GROWTH OF THE HUMAN MALARIA PARASITE P. FALCIPARUM BY ANTISENSE OLIGODEOXYNUCLEOTIDES (1996) (0)
Membrane-bound tumour necrosis factor alpha: immunocytochemical and ultrastructural studies of human monocytes and monocytic cell line and its induction by tumour cells in vitro. (1992) (0)
SYNTHESIS, CHEMISTRY AND STEREOCHEMISTRY OF PHOSPHORORGANIC THIOCYANATES P(X)SCN AND ISOTHIOCYANATES P(X)NCS, REARRANGEMENT OF THIO- INTO ISOTHIOCYANATES (1977) (0)
Studies on Enzymatic Hydrolysis of Thymidin‐3′‐yl Thymidin‐5′‐yl Phosphorofluoridates and the Corresponding Phosphorothiofluoridates. (2000) (0)
Enantiomeric 2-Anilino-2-oxo-1,3,2-oxazaphosphorinanes: Synthesis and NMR Investigation of Their Non-Racemic Mixtures. (1996) (0)
Methods and compounds for the solid phase synthesis of oligonucleotides and analogs (1992) (0)
The epidermal growth factor-like domain from tissue plasminogen activator. Cloning in E. coli, purification and ESR studies of its interaction with human blood platelets. (1994) (0)
A mutational study of individual functional groups on the G6 base of the 10-23 deoxyribozyme core (2006) (0)
Stereochemical Aspects of the Reaction of Dialkyl Phosphates with Amine in the Presence of Triphenylphosphine and Carbon Tetrachloride. (1986) (0)
Oxidation in Organophosphorus Chemistry: Potassium Peroxymonosulfate. (1999) (0)
Diastereomers of thymidine 3'-O-(methanephosphono-thioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis (1987) (0)
New Approach to Preparation of N-Acylphosphoramido(thio)(seleno)ates. (2004) (0)
Molecular analysis of the Drosophila JAK/STAT pathway receptor complex (2013) (0)
Stereocontrolled Syntheses of P-Chiral Analogues of Nucleoside Cyclic 3′,5′-Phosphates (2010) (0)
Expression of a human PAI-1 fusion peptide in E. coli and its immunochemical characterization (1994) (0)
Mapping of the function phosphate groups in the catalytic core of DNAzyme 10-23 (2006) (0)
The Synthesis of Dithymidine Boranophosphate by the Oxathiaphospholane Approach. (2002) (0)
Oligonucleotides antisense strategy (1994) (0)
SYNTHESIS OF A DIALKYL PHOSPHOROISOCYANIDATE (1975) (0)
Direct Transformation of Ribonucleoside Cyclic 3′,5′-Phosphorothioates into Cyclic 2′,3′-Phosphates. (1986) (0)
SYNTHESIS AND ABSOLUTE CONFIGURATION OF THE OPTICALLY ACTIVE FORMS OF 2-(BIS(2-CHLOROETHYL)AMINO)-4-METHYLTETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE (4-METHYLCYCLOPHOSPHAMIDE) (1977) (0)
Mixed Phosphorus-Carboxylic Anhydrides as Synthons for Stereoselective Synthesis of [RP]-Dinucleoside (3',5')-Methanephosphonates (1999) (0)
Phosphorus chemistry directed towards biology : lectures presented at the International Symposium on Phosphorus Chemistry Directed Towards Biology, Burzenin, Poland 25-28 September 1979 (1980) (0)
STEREORETENTIVE CONVERSION OF DIALKYL PHOSPHOROTHIOATES INTO (18O)-PHOSPHATES (1984) (0)
Oligo(nucleoside Phosphorothioate)s: The Quest of P-Chirality (2002) (0)
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer (2019) (0)
Novel Observation on Base-Catalyzed Benzoylation of Dialkyl Phosphoranilidates. (1987) (0)
Phosphorothioate modified DNAzymes (2005) (0)
Recent Advances in Stereocontrolled Synthesis of P-Chiral Analogues of Biophosphates. (2002) (0)
Synthesis of Adenosine Cyclic 3′,5′‐Phosphorofluoridate (cAMP‐F). (1996) (0)
SYNTHESIS OF ASYMMETRIC S,S,S-TRIALKYL PHOSPHOROTRITHIOATES (1977) (0)
High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) double cysteine mutant from rabbit (2010) (0)
Separation of [Sp]-3'-O-(5'-dimethoxytritylthymidyl)-5'-O-(3'camphanoyl thymidyl)-O-methyl phosphite. (1991) (0)
THYMIDINE 3′‐(2‐CHLOROPHENYL)‐PHOSPHORANILIDATE AS A KEY INTERMEDIATE IN THE SYNTHESIS OF TETRATHYMIDYLIC ACID BEARING PHOSPHORYL OR PHOSPHOROTHIOYL END GROUPS (1980) (0)
Process for production of oligonucleotide-analog containing sulfur (1991) (0)
Stereospecific synthesis and assignment of absolute configuration at phosphorus in nucleoside 3'- and 5'-O-arylphosphorothioates and nucleoside cyclic 3',5'-phosphorothioates (1981) (0)
Stereospecific Synthesis of P-Chiral Analogues of Oligonucleotides (1994) (0)
Crystals of recombinant human tumor necrosis factor (1991) (0)
REACTIONS OF DINEOPENTOXYPHOSPHINE (1976) (0)
Stereochemistry of the Michaelis-Becker Reaction of cis- and trans- 2-Hydro-2-oxo-4- methyl-l ,3,2-dioxaphosphorinan with Methyl Iodide. (1976) (0)
Biotechnology in Poland (1993) (0)
A New Class of Dinucleotide Analogues. The Synthesis of 3′‐O‐ Thymidylyl(5′‐deoxy‐5′‐selene‐thymidylyl)‐Se‐phosphoroselenolate, Its O‐Methyl Ester and Methanephosphonate Derivatives. (1994) (0)
Nucleophilic N1→N3 Rearrangement of 5′‐O‐Trityl‐O2,3‐cycloanhydrothymidine. (2002) (0)
Nucleoside-O-(2-thiono-1,3,2-oxathiaphospholane)S- Versatile Tools in the Synthesis of Oligonucleotide Analogues (2000) (0)
HCV NS5B Inhibitor PSI-6130 (2010) (0)
N‐Benzoyl O,O‐Dialkyl Phosphoranilidates: Reaction with O‐ and N‐ Nucleophiles. (1992) (0)
NEW SYNTHESIS AND ASSIGNMENT OF ABSOLUTE CONFIGURATION OF ENANTIOMERS OF O,S‐DIMETHYL PHOSPHORODITHIOATE (1980) (0)
High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C38A mutant from rabbit complexed with Adenosine (2010) (0)
One-pot synthesis of dinucleoside (3',5') methanephosphonothioates via phosphonotriazolidite approach (2005) (0)
Internalization of oligodeoxynucleotide antisense to type‐1 plasminogen activator inhibitor mRNA in endothelial cells: A three‐dimensional reconstruction by confocal microscopy (2004) (0)
AXIAL PREFERENCE OF A 2-ANILINOSUBSTITUENT IN 4-METHYL-1,3,2-DIOXAPHOSPHORINAN (1975) (0)
STEREOSPECIFIC SYNTHESIS OF THYMIDINE CYCLIC 3′,5′ (SP)- AND (RP)-PHOSPHOROTHIOATES (1978) (0)
SYNTHESIS AND PROPERTIES OF DIASTEREOISOMERIC 2-ISOTHIOCYANO-2-OXO-4-METHYL-1,3,2-DIOXAPHOSPHORINANS, THE ROLE OF NUCLEOPHILIC CATALYSIS IN THEIR EPIMERIZATION (1975) (0)
Stereospecific Synthesis of (Rp)- and (Sp)-Thymidylyl(3′,5′)thymidylyl Methanephosphonates. (1988) (0)
Synthesis of P-Chiral [ 18 O]-Labeled Isotopomeric Oligo(deoxyribonucleoside Phosphorothioate)s and Phosphates (2002) (0)
Synthesis of N -acyl phosphoramidate pronucleotides (2008) (0)
Comparative study on the immunosuppressive and lympholytic activity of optical isomers of cyclophosphamide. (1983) (0)
Oxathiaphospholane ring-opening condensation: from oligo(nucleoside phosphorothioate)s to P-chiral analogues of nucleoside polyphosphates (2008) (0)
Stereochemical support for Serratia endonuclease active-site geometry (2000) (0)
Synthesis and Structural Studies of SP and RP Diastereomers of Deoxyxylothymidyl‐3′‐O‐acetylthymidyl (3′,5′)‐O‐(2‐Cyanoethyl)phosphorothioate in Solution and in the Solid State. (2002) (0)
The Synthesis of 5′-O-DMT-Thymidine-3′-O-(2-thio-1,3,2- oxaselenaphospholane) and Its Possible Application in Stereocontrolled Synthesis of Oligo(nucleoside phosphorothioate)s. (1994) (0)
CRYSTALLOGRAPHIC ASSESSMENT OF ABSOLUTE CONFIGURATION IN 2′-DEOXYADENOSINE CYCLIC 3′,5′-(RP)-PHOSPHORANILIDATE. DIRECT PHOSPHORUS-31-NITROGEN-15 SPIN-SPIN COUPLING AS A PROBE FOR CONFIGURATIONAL ASSESSMENT (1981) (0)
Attempted stereoselective synthesis of P-chiral analogues of oligodeoxyribonucleotides. (1989) (0)
Reactivity of Nucleoside 5′-O-Phosphates, -Phosphorothioates, -Methanephosphonates, and -Methanephosphonothioates Toward Activated Xylonucleosides. (1999) (0)
Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope This work was financially supported by the State Committee for Scientific Research (KBN, Poland, Grant 4P05F00617, to W.J.S.), and, in part, by (2001) (0)
CHIRAL ANTICANCER OXAZAPHOSPHORINANES - STEREOSPECIFIC SYNTHESIS, CONFIGURATIONAL ASSIGNMENTS AND BIOLOGICAL EVALUATIONS (1980) (0)
Stereoselective Synthesis of [Rp]-Dinucleoside (3′,5′)-Methanephosphonates (1999) (0)
THE CHEMICAL SYNTHESIS OF THE RP AND SP DIASTEREOISOMERS OF THYMIDYL-(3′-5′)-THYMIDYL-O,O-PHOSPHOROTHIOATE (1983) (0)
Stereocontrolled Synthesis of LNA Dinucleoside Phosphorothioate by the Oxathiaphospholane Approach (2001) (0)
Methods for the synthesis of organo (1996) (0)
Stereochemical Analysis of Diastereomeric 1,3‐Bis(adenosine‐5′‐O‐phosphorothioyl)glycerols (2004) (0)
Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine (2004) (0)
Isolation and Identification of a Metabolic Intermediate in the Selective Dechloroethylation of One of the Four Stereoisomers of 4-Methylcyclophosphamide1 (2006) (0)
SYNTHESIS OF DIALKYL PHOSPHOROSELENOCYANATIDATES AND THEIR REARRANGEMENT TO DIALKYL PHOSPHORISOSELENOCYANATIDATES (1979) (0)
Chemo-and Stereoselectivity of Nucleophilic Substitution in Mixed Phosphorus-Carboxylic Anhydrides (1999) (0)
Synthesis and separation of diastereoisomers of 5'-O-(4,4'-dimethoxytrimethylphenyl)dithymidyl-(3,5')-4,4' -dimethoxytriphenylmethanephosphonate. (1987) (0)
A Novel Approach to the Preparationof Peptide-Oligonucleotide Conjugates (2009) (0)
Oxathiaphospholane approach to the synthesis of nucleoside 5'- O -[α-phosphorothio-β-alkanephosphonate] anhydrides (2008) (0)
Buchbesprechung: Phosphoric Anhydride. Structure, Chemistry and Applications. Von D. A. Efremov, P. M. Zavlin und J. C. Tebby. (2001) (0)
Differential effect of stereospecific analogues of nucleoside cyclic 3',5'phosphorus on the release of PAI-1 from human endothelial cells (1994) (0)
A NEW ROUTE TO O,O-DINUCLEOSIDE ESTERS OF PHOSPHOROTHIONIC ACID (1979) (0)
Deoxyribonucleoside 3′-Phosphordiamidites as Substrates for Solid Supported Synthesis of Oligodeoxyribonucleotides and Their Phosphorothioate and DNA-Triester Analogues. (1987) (0)
2′-DEOXYRIBONUCLEOSIDE 3′-ARYL PHOSPHORANILIDATES. KEY INTERMEDIATES IN THE STEREOSPECIFIC SYNTHESIS OF 2′-DEOXYRIBONUCLEOSIDE CYCLIC 3′,5′-PHOSPHOROTHIOATES AND DINUCLEOSIDE(3′ → 5′)-PHOSPHOROTHIOATES (1984) (0)
The Synthesis of P-Chiral Optically Pure Phosphorothioates, Phopshorotrithioates, Phosphoroselenothioates, Methanephosphonothioates, and Methylphenylphosphinothioates. (1991) (0)
The Synthesis and X-Ray Structural Studies of Bis(1,3,2-Dithiaphospholane) (1999) (0)
ChemInform Abstract: Thiophosphorylation of Biologically Relevant Alcohols by the Oxathiaphospholane Approach. (2002) (0)
Inhibition of ADP‐Triggered Blood Platelet Aggregation by Diadenosine Polyphosphate Analogues. (2002) (0)
Preparation of 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and alkyl substituted purines and their derivatives (2005) (0)
A NEW APPROACH TO SYNTHESES OF ORGANIC PHOSPHOROSELENOATES AND PHOSPHORODISELENOATES. PROOF OF ABSOLUTE CONFIGURATION ASSIGNMENT IN DIASTEREOMERS OF CTMPS (THYMIDINE CYCLIC 3′,5′-PHOSPHOROTHIOATES) (1980) (0)

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What Schools Are Affiliated With Wojciech J. Stec?

Wojciech J. Stec is affiliated with the following schools:

University of Sheffield
Emory University