Wolfgang Maret
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Wolfgang Maretbiology Degrees
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Medical Biology
Wolfgang Maret's Degrees
- PhD Biochemistry University of California, Berkeley
Why Is Wolfgang Maret Influential?
(Suggest an Edit or Addition)Wolfgang Maret's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Zinc requirements and the risks and benefits of zinc supplementation. (2006) (943)
- Thiolate ligands in metallothionein confer redox activity on zinc clusters. (1998) (528)
- Zinc biochemistry: from a single zinc enzyme to a key element of life. (2013) (510)
- Coordination dynamics of zinc in proteins. (2009) (454)
- The biological inorganic chemistry of zinc ions☆ (2016) (445)
- Control of zinc transfer between thionein, metallothionein, and zinc proteins. (1998) (444)
- The function of zinc metallothionein: a link between cellular zinc and redox state. (2000) (378)
- Inhibitory sites in enzymes: zinc removal and reactivation by thionein. (1999) (371)
- Cytosolic zinc buffering and muffling: their role in intracellular zinc homeostasis. (2010) (369)
- Zinc-buffering capacity of a eukaryotic cell at physiological pZn (2006) (356)
- Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange. (1994) (317)
- Zinc coordination environments in proteins as redox sensors and signal transducers. (2006) (280)
- The glutathione redox couple modulates zinc transfer from metallothionein to zinc-depleted sorbitol dehydrogenase. (1998) (271)
- Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling. (2003) (267)
- Zinc metallothionein imported into liver mitochondria modulates respiration (2001) (248)
- Dual nanomolar and picomolar Zn(II) binding properties of metallothionein. (2007) (244)
- Molecular aspects of human cellular zinc homeostasis: redox control of zinc potentials and zinc signals (2009) (235)
- The zinc/thiolate redox biochemistry of metallothionein and the control of zinc ion fluctuations in cell signaling. (2007) (232)
- Zinc and sulfur: a critical biological partnership. (2004) (231)
- Zinc in Cellular Regulation: The Nature and Significance of “Zinc Signals” (2017) (226)
- Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro (2010) (198)
- Cellular zinc and redox states converge in the metallothionein/thionein pair. (2003) (191)
- Metals on the move: zinc ions in cellular regulation and in the coordination dynamics of zinc proteins (2011) (184)
- Cellular Zinc and Redox Buffering Capacity of Metallothionein/Thionein in Health and Disease (2007) (179)
- Analyzing free zinc(II) ion concentrations in cell biology with fluorescent chelating molecules. (2015) (172)
- Protein Tyrosine Phosphatases as Targets of the Combined Insulinomimetic Effects of Zinc and Oxidants (2005) (168)
- The Functions of Metamorphic Metallothioneins in Zinc and Copper Metabolism (2017) (167)
- Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc (1995) (166)
- Cobalt as probe and label of proteins. (1993) (158)
- Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc (2008) (153)
- New perspectives of zinc coordination environments in proteins. (2012) (152)
- The bioinorganic chemistry of cadmium in the context of its toxicity. (2013) (151)
- The Metals in the Biological Periodic System of the Elements: Concepts and Conjectures (2016) (149)
- Redox biochemistry of mammalian metallothioneins (2011) (146)
- Picomolar Concentrations of Free Zinc(II) Ions Regulate Receptor Protein-tyrosine Phosphatase β Activity* (2012) (137)
- Zinc biochemistry, physiology, and homeostasis – recent insights and current trends (2001) (136)
- Zinc coordination environments in proteins determine zinc functions. (2005) (134)
- Thionein/metallothionein control Zn(II) availability and the activity of enzymes (2008) (132)
- Metalloproteomics, metalloproteomes, and the annotation of metalloproteins. (2010) (131)
- Selenium redox biochemistry of zinc-sulfur coordination sites in proteins and enzymes. (1999) (126)
- Binding, transport and storage of metal ions in biological cells (2014) (123)
- Fluctuations of cellular, available zinc modulate insulin signaling via inhibition of protein tyrosine phosphatases. (2005) (121)
- Differential fluorescence labeling of cysteinyl clusters uncovers high tissue levels of thionein (2001) (120)
- Zinc and Excitotoxic Brain Injury: A New Model (2004) (119)
- Site-specific substituted cobalt(II) horse liver alcohol dehydrogenases. Preparation and characterization in solution, crystalline and immobilized state. (1979) (117)
- Zinc transfer potentials of the α- and β-clusters of metallothionein are affected by domain interactions in the whole molecule (2000) (117)
- Different redox states of metallothionein/thionein in biological tissue. (2007) (111)
- Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts. (2005) (110)
- The redox biology of redox-inert zinc ions. (2019) (108)
- S-nitrosothiols react preferentially with zinc thiolate clusters of metallothionein III through transnitrosation. (2002) (108)
- Coordination dynamics of biological zinc "clusters" in metallothioneins and in the DNA-binding domain of the transcription factor Gal4. (1997) (104)
- Transient fluctuations of intracellular zinc ions in cell proliferation. (2009) (102)
- Zinc in Pancreatic Islet Biology, Insulin Sensitivity, and Diabetes (2017) (95)
- Zinc and human disease. (2013) (91)
- Zinc ions modulate protein tyrosine phosphatase 1B activity. (2014) (89)
- Catalytic selenols couple the redox cycles of metallothionein and glutathione. (2001) (87)
- Inhibitory zinc sites in enzymes (2013) (86)
- Crosstalk of the group IIa and IIb metals calcium and zinc in cellular signaling (2001) (86)
- Ebselen, a selenium-containing redox drug, releases zinc from metallothionein. (1998) (84)
- The ATP-metallothionein complex. (1998) (74)
- Aldehydes release zinc from proteins. A pathway from oxidative stress/lipid peroxidation to cellular functions of zinc (2006) (70)
- Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease. (2005) (67)
- Human metallothionein metallomics (2008) (66)
- The metal face of protein tyrosine phosphatase 1B☆ (2016) (65)
- Purification and characterization of human liver sorbitol dehydrogenase. (1988) (62)
- Possible roles of zinc nutriture in the fetal origins of disease (2008) (61)
- Intracellular zinc in insulin secretion and action: a determinant of diabetes risk? (2015) (59)
- Genetic causes and gene–nutrient interactions in mammalian zinc deficiencies: acrodermatitis enteropathica and transient neonatal zinc deficiency as examples. (2015) (54)
- Retinal is not formed in vitro by enzymatic central cleavage of beta-carotene. (1988) (51)
- A fluorescence resonance energy transfer sensor for the β-domain of metallothionein (2003) (51)
- Extrahepatic, differential expression of four classes of human alcohol dehydrogenase. (1993) (50)
- Exploring the zinc proteome (2004) (50)
- A differential assay for the reduced and oxidized states of metallothionein and thionein. (2004) (45)
- The ATP/metallothionein interaction: NMR and STM. (2002) (45)
- Active site-specific reconstituted copper(II) horse liver alcohol dehydrogenase: a biological model for type 1 Cu2+ and its changes upon ligand binding and conformational transitions. (1980) (43)
- Neutral metal-bound water is the base catalyst in liver alcohol dehydrogenase. (1983) (42)
- Lipid raft‐dependent endocytosis of metallothionein in HepG2 cells (2007) (41)
- Coordination Dynamics of Zinc in Proteins (2010) (41)
- High yield expression and single step purification of human thionein/metallothionein. (2001) (39)
- Zinc and the zinc proteome. (2013) (38)
- Variability within mammalian sorbitol dehydrogenases. The primary structure of the human liver enzyme. (1989) (35)
- The Bioinorganic Chemistry of Lead in the Context of Its Toxicity. (2017) (35)
- Enzyme regulation by reversible zinc inhibition: glycerol phosphate dehydrogenase as an example. (2001) (35)
- Cobalt(II)-substituted class III alcohol and sorbitol dehydrogenases from human liver. (1989) (35)
- Zinc transfer potentials of the alpha - and beta-clusters of metallothionein are affected by domain interactions in the whole molecule. (2000) (34)
- The Bioinorganic Chemistry of Mammalian Metallothioneins. (2021) (34)
- Metal ion substitution at the catalytic site of horse-liver alcohol dehydrogenase: results from solvent magnetic relaxation studies. 1. Copper(II) and cobalt(II) ions. (1981) (33)
- The relationship between transient zinc ion fluctuations and redox signaling in the pathways of secondary cellular injury: Relevance to traumatic brain injury (2010) (33)
- Partial oxidation and oxidative polymerization of metallothionein (2008) (30)
- Proton NMR investigation of the active site of cobalt(II)-substituted liver alcohol dehydrogenase (1984) (30)
- Fluorescent probes for the structure and function of metallothionein. (2009) (29)
- The C‐terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant (2018) (29)
- Catalytic oxidation of zinc/sulfur coordination sites in proteins by selenium compounds. (2001) (28)
- Active-site-specific reconstituted cobalt(II) horse-liver alcohol dehydrogenase. Changes of the spectra of the substrate trans-4-(N,N-dimethylamino)-cinnamaldehyde and of the catalytic cobalt ion upon ternary complex formation with NADH and 1,4,5,6-tetrahydronicotinamide--adenine dinucleotide. (1979) (28)
- Metallomics: The Science of Biometals and Biometalloids. (2018) (27)
- The Final Frontier of pH and the Undiscovered Country Beyond (2012) (27)
- Active site-specifically reconstituted nickel(II) horse liver alcohol dehydrogenase: optical spectra of binary and ternary complexes with coenzymes, coenzyme analogues, substrates, and inhibitors. (1981) (25)
- Resonance Raman spectroscopy in blue copper proteins: ligand and coenzyme effects in copper(II)-substituted liver alcohol dehydrogenase (1986) (23)
- The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis (2020) (23)
- Domain-specific fluorescence resonance energy transfer (FRET) sensors of metallothionein/thionein. (2005) (23)
- Protein Interface Zinc Sites: The Role of Zinc in the Supramolecular Assembly of Proteins and in Transient Protein–Protein Interactions (2006) (22)
- Influence of anions and pH on the conformational change of horse liver alcohol dehydrogenase induced by binding of oxidized nicotinamide adenine dinucleotide: binding of chloride to the catalytic metal ion. (1986) (22)
- Coordination chemistry and function of the catalytic metal ion in liver alcohol dehydrogenase (1984) (22)
- Chromium Supplementation in Human Health, Metabolic Syndrome, and Diabetes. (2019) (22)
- Zinc and Cadmium in the Aetiology and Pathogenesis of Osteoarthritis and Rheumatoid Arthritis (2020) (21)
- Differential cytolocation and functional assays of the two major human SLC30A8 (ZnT8) isoforms. (2017) (21)
- Genetics of Human Zinc Deficiencies (2016) (19)
- Optical methods for measuring zinc binding and release, zinc coordination environments in zinc finger proteins, and redox sensitivity and activity of zinc-bound thiols. (2002) (18)
- Ligand Binding to the blue copper center of horse liver alcohol dehydrogenase (1981) (18)
- Metal ion substitution at the catalytic site of horse-liver alcohol dehydrogenase: results from solvent magnetic relaxation studies. 2. Binding of manganese(II) and competition with zinc(II) and cadmium(II) ions. (1981) (18)
- Human liver aldehyde dehydrogenases: new method of purification of the major mitochondrial and cytosolic enzymes and re-evaluation of their kinetic properties. (1994) (18)
- Zinc proteomics and the annotation of the human zinc proteome (2008) (17)
- The interactions of metal cations and oxyanions with protein tyrosine phosphatase 1B (2017) (17)
- Role of Zinc and Magnesium Ions in the Modulation of Phosphoryl Transfer in Protein Tyrosine Phosphatase 1B. (2018) (17)
- The Regulatory and Signaling Functions of Zinc Ions in Human Cellular Physiology (2010) (17)
- Redox and zinc signalling pathways converging on protein tyrosine phosphatases. (2014) (16)
- Zinc Biochemistry, Physiology, and Homeostasis (2001) (15)
- The pH variation of steady-state kinetic parameters of site-specific Co(2+)-reconstituted liver alcohol dehydrogenase. A mechanistic probe for the assignment of metal-linked ionizations. (1991) (15)
- Redox Control of Zinc Finger Proteins: Mechanisms and Role in Gene Regulation (2001) (15)
- Resonance Raman spectra of copper(II)-substituted liver alcohol dehydrogenase: a type 1 copper analogue. (1983) (15)
- A role for metallothionein in the pathogenesis of diabetes and its cardiovascular complications. (2008) (14)
- Agarose-bound horse-liver alcohol dehydrogenase. Dependence of molecular properties and activity on coupling conditions. (1978) (13)
- Total Iron Measurement in Human Serum With a Novel Smartphone-Based Assay (2020) (13)
- Electronic absorption and EPR spectroscopy of copper alcohol dehydrogenase: pink, violet and green forms of a type 1 copper center analog. (1987) (13)
- Regulation of Cellular Zinc Ions and Their Signaling Functions (2019) (13)
- Fe(II)-substituted horse liver alcohol dehydrogenase, a model for non-heme iron enzymes. Various states of iron-dioxygen interaction investigated by Mössbauer and EPR spectroscopy. (1989) (12)
- Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets (2017) (12)
- A fluorescence resonance energy transfer sensor for the beta-domain of metallothionein. (2003) (12)
- Metallomics: A Primer of Integrated Biometal Sciences (2016) (12)
- Novel substrates and inhibitors of human liver sorbitol dehydrogenase. (1991) (11)
- Molecular Aspects of Zinc Signals (2014) (11)
- A scanning tunneling microscopy study of rabbit metallothionein (1998) (11)
- Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a. (2020) (10)
- Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers. (2018) (10)
- Zinc and Diabetes (2005) (9)
- Human sorbitol dehydrogenase--a secondary alcohol dehydrogenase with distinct pathophysiological roles. pH-dependent kinetic studies. (1997) (9)
- Metallomics: whence and whither. (2012) (8)
- Plasma mineral (selenium, zinc or copper) concentrations in the general pregnant population, adjusted for supplement intake, in relation to thyroid function (2020) (8)
- X-ray absorption edge spectroscopy of Co(II)-binding sites of copper- and zinc-containing proteins. (1981) (7)
- Assessment of coupled Zn concentration and natural stable isotope analyses of urine as a novel probe of Zn status. (2019) (7)
- Alcohol dehydrogenase genes: restriction fragment length polymorphisms for ADH4 (π-ADH) and ADH5 (χ-ADH) and construction of haplotypes among different ADH classes (1992) (6)
- The biological inorganic chemistry of zinc ions * and Biophysics (2016) (6)
- An EPR study of the blue copper center in horse liver alcohol dehydrogenase. (1983) (6)
- Metallothionein and the acute phase response. (1995) (6)
- Zinc enzymes (metal ions in biology, vol 5) (1984) (5)
- ZnT8 Haploinsufficiency Impacts MIN6 Cell Zinc Content and β-Cell Phenotype via ZIP-ZnT8 Coregulation (2019) (5)
- Comparative outcomes of exposing human liver and kidney cell lines to tungstate and molybdate (2021) (5)
- Zinc in the biosciences. (2014) (5)
- [9] Preparation of metal-hybrid enzymes (1988) (5)
- 805—Polarographic study og horseliver alcohol dehydrogenase lacking zinc ions at the active sites (1984) (5)
- Meeting Report: Zinc Signals 2007—Expanding Roles of the Free Zinc Ion in Biology (2007) (5)
- Detecting metal-metal interactions and measuring distances between metal centers in metalloproteins. (1993) (4)
- Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28-30, 2016 - Israel. (2018) (4)
- The catalytic action of Zn2+-metalloenzymes requires a penta-coordinate metal-OH2 complex (1984) (4)
- Regulation of metal ions (2016) (4)
- The influence of anions and inhibitors on the catalytic metal ion in Co(II)-substituted horse liver alcohol dehydrogenase (2004) (3)
- An Appraisal of the Field of Metallomics and the Roles of Metal Ions in Biochemistry and Cell Signaling (2021) (3)
- The quintessence of metallomics: a harbinger of a different life science based on the periodic table of the bioelements (2022) (3)
- Mössbauer characterization of the Fe−S center in the catalytic metal binding site of alcohol dehydrogenase (1986) (2)
- Resonance Raman Spectroscopy of Blue Copper Proteins: Ligand and Coenzyme Effects in Copper(II)-Substituted Liver Alcohol Dehydrogenase (1987) (2)
- Oxidative Stress Mediated by Trace Elements Cellular Zinc and Redox States Converge in the Metallothionein/Thionein Pair 1,2 (2003) (2)
- Preparation of metal-hybrid enzymes. (1988) (2)
- Methods and Technologies for Studying Metals in Biological Systems (2015) (2)
- An MspI RFLP in the human ADH5 gene. (1990) (2)
- Binding of ligands to horse liver alcohol dehydrogenase lacking zinc ions at the active sites. (1986) (2)
- THIOL REACTIVITY AS A CENTRAL ASPECT OF METALLOTHIONEIN'S MECHANISM OF ACTION (2008) (2)
- Differential cytolocation and functional assays of the two major SLC 30 A 8 ( ZnT 8 ) isoforms (2017) (2)
- Teaching the chemical elements in biochemistry: Elemental biology and metallomics (2022) (2)
- The Glutathione Redox State and Zinc Mobilization from Metallothionein and Other Proteins with Zinc–Sulfur Coordination Sites (2018) (2)
- The interaction of catalytic metal ions and ionizing groups in equilibrium studies and in transient intermediates of metal-substituted alcohol dehydrogenases. (1985) (1)
- Does the Coordination Environment Determine the Reactivity of Metals in Enzymes (1986) (1)
- The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis (2020) (1)
- Iron and zinc sensing in cells and the body. (2015) (1)
- Escort proteins for cellular zinc ions (2022) (1)
- Redox biochemistry of metallothioneins and protein tyrosine phosphatases in growth factor signalling (2012) (1)
- Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions (2021) (1)
- EXAFS INVESTIGATION OF THE STRUCTURAL SITE OF LIVER ALCOHOL DEHYDROGENASE (1986) (1)
- Plasma mineral (Se, Zn or Cu) concentrations in the general pregnant population, adjusted for supplement intake, in relation to thyroid function (2020) (0)
- Inhibitory sites in enzymes: Zinc reactivation by thionein (2016) (0)
- Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier (2022) (0)
- Metallomic profiling in human coronary artery endothelial cells: effects of physiological oxygen levels and ischemia-reoxygenation injury (2021) (0)
- Direct Transformation of Carboxylic Acids into Aldehydes (2020) (0)
- Functions of the C-terminus in Zinc Transporter-1 (ZnT1) as assessed by Mutant Zebrafish, slc30a1sa17 (2013) (0)
- Non-essential elements (2016) (0)
- Nrf2-regulated redox signaling in human coronary smooth artery smooth muscle cells under hyperoxia, physiological normoxia and hypoxia (2021) (0)
- 14.00-14.15 Welcome and opening remarks (2014) (0)
- NMR of paramagnetic molecules in biological systems: Vol. 3, Physical Bioinorganic Chemistry Series. By Ivano Bertini and Claudio Luchinat, Benjamin/Cummings. Menlo Park, CA, 1986. xvi + 319 pp. $38.95 (1987) (0)
- Effects of changes in ambient oxygen levels and hypoxia-reoxygenation on intracellular zinc levels in human coronary artery endothelial cells (2021) (0)
- Bert Vallee—A 20th Century Adventure(r) in Zincology (2021) (0)
- Selenium redox biochemistry of proteins and enzymes (2016) (0)
- Inhibitory zinc sites in enzymes (2013) (0)
- The catalytically competent coordination environment of the active site metal ion of liver alcohol dehydrogenase (1983) (0)
- Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets (2017) (0)
- Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc. (2023) (0)
- The interactions of metal cations and oxyanions with protein tyrosine phosphatase 1B (2017) (0)
- Biological Monitoring of Exposure to Chemicals: Metals. Edited by H. Kenneth Dillon and Mat H. Ho. Wiley, New York, 1991. Xvii + 280 pp., $80.00. (1993) (0)
- The chemical elements of life (2016) (0)
- The first trimester plasma copper-zinc ratio is independently related to pregnancy-specific psychological distress symptoms throughout pregnancy. (2022) (0)
- The Role of the Biometal Zinc in Diabetes in Relation to Other (Bio)metal Ions (2016) (0)
- Nuclear and electron relaxation : Lucia Band, Ivano Bertini, and Claudio Luchinat VCH Publishers, New York, 1991 ISBN 1-56081-145-5 209 + XVI pages (1994) (0)
- Inhibition of Zinc Transporter ZIP6/ZIP10 Heteromer Prevents the Zinc Influx Required to Trigger Mitosis (2019) (0)
- Neutral metal-bound water is the b alcohol dehydrogenase (electron paramagnetic resonance/oxygen-17/pH dependence of kin( (2016) (0)
- A Correction to the Perspective Titled "Meeting Report: Zinc Signals 2007—Expanding Roles of the Free Zinc Ion in Biology" by C. Frederickson et al. (2007) (0)
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What Schools Are Affiliated With Wolfgang Maret?
Wolfgang Maret is affiliated with the following schools:
