Wolfgang Wagner
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Stem cell biology professor at RWTH Aachen University Medical School
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Biology
Wolfgang Wagner's Degrees
- PhD Stem Cell Biology University of Cologne
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(Suggest an Edit or Addition)Wolfgang Wagner's Published Works
Published Works
- Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. (2005) (1233)
- Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process (2008) (1013)
- Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma (2004) (830)
- Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. (2010) (788)
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites (2014) (659)
- Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells (2003) (438)
- Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells (2009) (419)
- Pancreatic fistula after pancreatic head resection (2000) (417)
- DNA methylation aging clocks: challenges and recommendations (2019) (393)
- DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells (2010) (393)
- VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma (2008) (363)
- SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas (2021) (322)
- Surface topography enhances differentiation of mesenchymal stem cells towards osteogenic and adipogenic lineages. (2015) (287)
- Mesenchymal Stem Cell Preparations—Comparing Apples and Oranges (2007) (268)
- Heterogeneity of mesenchymal stromal cell preparations. (2008) (261)
- Overexpression of c‐myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway (2006) (252)
- Epigenetic-aging-signature to determine age in different tissues (2011) (249)
- Modeling of asymmetric cell division in hematopoietic stem cells--regulation of self-renewal is essential for efficient repopulation. (2009) (241)
- NF-κB/Rel activation in cerulein pancreatitis (1999) (231)
- Randomized clinical trial of pylorus‐preserving duodenopancreatectomy versus classical Whipple resection—long term results (2005) (227)
- Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells. (2014) (222)
- Molecular and Secretory Profiles of Human Mesenchymal Stromal Cells and Their Abilities to Maintain Primitive Hematopoietic Progenitors (2007) (216)
- Role of MT‐MMPs and MMP‐2 in pancreatic cancer progression (2000) (208)
- A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. (2001) (208)
- Calcification or dedifferentiation: Requirement to lock mesenchymal stem cells in a desired differentiation stage (2009) (205)
- Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation. (2015) (203)
- Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice. (1998) (200)
- Different facets of aging in human mesenchymal stem cells. (2010) (199)
- The heterogeneity of human mesenchymal stem cell preparations--evidence from simultaneous analysis of proteomes and transcriptomes. (2006) (193)
- Mitogenic and antiapoptotic role of constitutive NF‐κB/Rel activity in pancreatic cancer (2003) (188)
- 3'-[18F]fluoro-3'-deoxythymidine ([18F]-FLT) as positron emission tomography tracer for imaging proliferation in a murine B-Cell lymphoma model and in the human disease. (2003) (181)
- WNT5A--target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer. (2007) (178)
- Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells (2014) (176)
- Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks (2011) (174)
- CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness. (2005) (166)
- 3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche. (2012) (162)
- Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells (2009) (162)
- Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling (2016) (159)
- Evidence for reactive oxygen species inducing mutations in mammalian cells. (1986) (159)
- Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells. (2010) (147)
- How to track cellular aging of mesenchymal stromal cells? (2010) (147)
- Stat3 and NF-κB activation prevents apoptosis in pancreatic carcinogenesis ☆ ☆☆ (2002) (144)
- Molecular evidence for stem cell function of the slow-dividing fraction among human hematopoietic progenitor cells by genome-wide analysis. (2004) (132)
- Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications. (2015) (132)
- HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer (2015) (131)
- DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy (2016) (127)
- Donor Age of Human Platelet Lysate Affects Proliferation and Differentiation of Mesenchymal Stem Cells (2012) (125)
- Specific Age-Associated DNA Methylation Changes in Human Dermal Fibroblasts (2011) (125)
- MicroRNAs are shaping the hematopoietic landscape (2012) (124)
- HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types. (2018) (121)
- Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions (2010) (121)
- The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation (2016) (120)
- Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction. (2007) (119)
- SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo. (2003) (119)
- Pluripotent stem cells escape from senescence-associated DNA methylation changes (2013) (115)
- Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. (2007) (115)
- Mesenchymal stem cells and cardiac repair (2008) (114)
- Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies (2017) (109)
- Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGF-beta1 transgenic mouse model. (2001) (106)
- Population dynamics of mesenchymal stromal cells during culture expansion. (2012) (104)
- Epigenetic Aging Signatures Are Coherently Modified in Cancer (2015) (99)
- Expansion of Adipose Mesenchymal Stromal Cells is Affected by Human Platelet Lysate and Plating Density (2011) (98)
- Isolation of human mesenchymal stromal cells is more efficient by red blood cell lysis. (2008) (98)
- Monitoring of cellular senescence by DNA‐methylation at specific CpG sites (2012) (98)
- Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation. (2001) (97)
- NF-kappaB/Rel activation in cerulein pancreatitis. (1999) (97)
- Adipogenic differentiation of human mesenchymal stromal cells is down‐regulated by microRNA‐369‐5p and up‐regulated by microRNA‐371 (2011) (96)
- Aging of hematopoietic stem cells is regulated by the stem cell niche (2008) (94)
- Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition (2015) (93)
- Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice. (2014) (90)
- Effect of preoperative biliary drainage on surgical outcome after pancreatoduodenectomy. (2001) (90)
- Hematopoietic Progenitor Cells and Cellular Microenvironment: Behavioral and Molecular Changes upon Interaction (2005) (88)
- The Sphingosine-1-Phosphate (S1P) Lysophospholipid Receptor S1P3 Regulates MAdCAM-1+ Endothelial Cells in Splenic Marginal Sinus Organization (2004) (84)
- Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures (2016) (84)
- Synergistic effects of growth factors and mesenchymal stromal cells for expansion of hematopoietic stem and progenitor cells. (2011) (84)
- Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis. (2002) (83)
- LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat (2018) (83)
- Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) in pancreatic cancer cell lines (2002) (80)
- ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage. (2017) (78)
- Resistance of polysaccharide coatings to proteins, hematopoietic cells, and marine organisms. (2009) (77)
- Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours (2010) (75)
- Stem cells and ageing (2005) (74)
- An audit of outcomes of a series of periampullary carcinomas. (2009) (72)
- Increased expression of transforming growth factor beta s after acute oedematous pancreatitis in rats suggests a role in pancreatic repair. (1997) (72)
- Caerulein-induced NF-κB/Rel activation requires both Ca2+ and protein kinase C as messengers. (1999) (71)
- N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells. (2010) (67)
- Heparin concentration is critical for cell culture with human platelet lysate. (2013) (66)
- The CXCR4 antagonist AMD3100 releases a subset of G-CSF-primed peripheral blood progenitor cells with specific gene expression characteristics. (2006) (65)
- Senescence‐associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells (2016) (64)
- K14 mRNA reprogramming for dominant epidermolysis bullosa simplex. (2010) (64)
- Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells (2017) (63)
- Matrix elasticity, replicative senescence and DNA methylation patterns of mesenchymal stem cells. (2014) (60)
- Role of Extracellular Matrix in Pancreatic Diseases (1998) (60)
- Modeling of replicative senescence in hematopoietic development (2009) (60)
- Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas. (2003) (60)
- The beauty of asymmetry: asymmetric divisions and self-renewal in the haematopoietic system (2007) (58)
- Adhesion of Human Hematopoietic Progenitor Cells to Mesenchymal Stromal Cells Involves CD44 (2007) (57)
- Smad-Sp1 complexes mediate TGFbeta-induced early transcription of oncogenic Smad7 in pancreatic cancer cells. (2006) (56)
- Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells. (2002) (56)
- Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancer (2008) (56)
- The epigenetic tracks of aging (2014) (54)
- The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell–derived sensory neurons of erythromelalgia patients (2019) (53)
- Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells (2019) (53)
- The Tumor Suppressor KLF11 Mediates a Novel Mechanism in Transforming Growth Factor β–Induced Growth Inhibition That Is Inactivated in Pancreatic Cancer (2006) (52)
- Stem cells and ageing. The potential of stem cells to overcome age-related deteriorations of the body in regenerative medicine. (2005) (52)
- Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. (2013) (52)
- Progression-Free Survival in Ovarian Cancer Is Reflected in Epigenetic DNA Methylation Profiles (2011) (52)
- Hypoxic/normoxic preconditioning increases endothelial differentiation potential of human bone marrow CD133+ cells. (2010) (51)
- Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites (2015) (49)
- IgG4-related autoimmune diseases: Polymorphous presentation complicates diagnosis and treatment. (2015) (48)
- Epigenetic Classification of Human Mesenchymal Stromal Cells (2016) (48)
- The Many Facets of SDF-1α, CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells (2007) (48)
- New targeted approaches for epigenetic age predictions (2019) (47)
- TGFα Transgenic Mice (2001) (47)
- Acute anoxia stimulates proliferation in adult neural stem cells from the rat brain (2008) (46)
- Effects of senolytic drugs on human mesenchymal stromal cells (2018) (45)
- A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation (2018) (44)
- Human platelet lysate gel provides a novel three dimensional-matrix for enhanced culture expansion of mesenchymal stromal cells. (2012) (44)
- Standardized isolation of human mesenchymal stromal cells with red blood cell lysis. (2011) (43)
- Standard surgical treatment in pancreatic cancer. (1999) (43)
- Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells. (2021) (40)
- Cellular immune reaction in the pancreas is induced by constitutively active IκB kinase-2 (2006) (39)
- The Link Between Epigenetic Clocks for Aging and Senescence (2019) (39)
- Increased DNA methylation of Dnmt3b targets impairs leukemogenesis. (2016) (38)
- Time-Dependent Toxic and Genotoxic Effects of Zinc Oxide Nanoparticles after Long-Term and Repetitive Exposure to Human Mesenchymal Stem Cells (2017) (38)
- Epigenetic age-predictor for mice based on three CpG sites (2018) (38)
- Epigenetic aging clocks in mice and men (2017) (38)
- Feedback Signals in Myelodysplastic Syndromes: Increased Self-Renewal of the Malignant Clone Suppresses Normal Hematopoiesis (2014) (38)
- Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor α (1999) (38)
- Pylorus-Preserving Total Pancreatectomy (2001) (37)
- Epigenetic Biomarker to Support Classification into Pluripotent and Non-Pluripotent Cells (2015) (36)
- Reirradiation Using Carbon Ions in Patients with Locally Recurrent Rectal Cancer at HIT: First Results (2014) (36)
- Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer (2020) (35)
- The cAMP/Epac1/Rap1 pathway in pancreatic carcinoma. (2008) (35)
- The Stromal Activity of Mesenchymal Stromal Cells (2008) (35)
- Long-Term IKK2/NF-κB Signaling in Pancreatic β-Cells Induces Immune-Mediated Diabetes (2014) (33)
- Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and aging (2018) (33)
- Why the impact of mechanical stimuli on stem cells remains a challenge (2018) (32)
- Characterization of extracellular matrix proteoglycan transcripts expressed by vascular smooth muscle cells. (1990) (32)
- TGF-β stimulation in human and murine cells reveals commonly affected biological processes and pathways at transcription level (2014) (32)
- Implications of long-term culture for mesenchymal stem cells: genetic defects or epigenetic regulation? (2012) (32)
- TGF-beta1 Does Not Induce Senescence of Multipotent Mesenchymal Stromal Cells and Has Similar Effects in Early and Late Passages (2013) (31)
- Hematopoietic Stem and Progenitor Cells Acquire Distinct DNA-Hypermethylation During in vitro Culture (2013) (31)
- Fecal transplant in refractory Clostridium difficile colitis. (2013) (31)
- Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging (2017) (30)
- Pancreatic Stellate Cells Potentiate Proinvasive Effects of SERPINE2 Expression in Pancreatic Cancer Xenograft Tumors (2007) (30)
- To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture (2013) (30)
- TGF alpha transgenic mice. A model of pancreatic cancer development. (2001) (29)
- Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes (2014) (28)
- Acinar‐Ductal‐Carcinoma Sequence in Transforming Growth Factor‐α Transgenic Mice (1999) (27)
- Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness. (2016) (26)
- The impact of different types of surgery in pancreatic cancer. (1999) (26)
- Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas (2013) (26)
- Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice (2020) (25)
- Epigenetic Clocks Are Not Accelerated in COVID-19 Patients (2020) (25)
- Tracking of replicative senescence in mesenchymal stem cells by colony-forming unit frequency. (2013) (25)
- Primary Osteoporosis Is Not Reflected by Disease‐Specific DNA Methylation or Accelerated Epigenetic Age in Blood (2018) (25)
- Epigenetic biomarker to determine replicative senescence of cultured cells. (2013) (23)
- Influence of platelet-derived growth factor-AB on tissue development in autologous platelet-rich plasma gels. (2011) (23)
- Caerulein-induced NF-kappaB/Rel activation requires both Ca2+ and protein kinase C as messengers. (1999) (23)
- Modeling SDF-1-induced mobilization in leukemia cell lines. (2012) (23)
- Does soft really matter? Differentiation of induced pluripotent stem cells into mesenchymal stromal cells is not influenced by soft hydrogels. (2018) (22)
- ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (22)
- Gene expression analysis of an epidermolysis bullosa simplex Dowling‐Meara cell line by subtractive hybridization: recapitulation of cellular differentiation, migration and wound healing (2012) (22)
- Retroviral Integration Sites Correlate with Expressed Genes in Hematopoietic Stem Cells (2005) (21)
- Quantification of inflammatory activity in patients with Crohn’s disease using diffusion weighted imaging (DWI) in MR enteroclysis and MR enterography (2017) (21)
- In vivo evaluation of 5-[(18)F]fluoro-2'-deoxyuridine as tracer for positron emission tomography in a murine pancreatic cancer model. (2001) (21)
- Acinar-ductal-carcinoma sequence in transforming growth factor-alpha transgenic mice. (1999) (21)
- Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice. (2010) (20)
- Hsp72 Overexpression Accelerates the Recovery from Caerulein-Induced Pancreatitis (2012) (20)
- A review of the biomedical innovations for healthy longevity (2017) (20)
- KATP channels in mesenchymal stromal stem cells: strong up-regulation of Kir6.2 subunits upon osteogenic differentiation. (2011) (20)
- Functional potentials of human hematopoietic progenitor cells are maintained by mesenchymal stromal cells and not impaired by plerixafor. (2014) (20)
- Cell Mechanics in Embryoid Bodies (2020) (20)
- Pylorus-preserving total pancreatectomy. Early and late results. (2001) (20)
- Do age‐associated DNA methylation changes increase the risk of malignant transformation? (2015) (19)
- A three-gene expression-based risk score can refine the European LeukemiaNet AML classification (2016) (19)
- DDX5 is a multifunctional co-activator of steroid hormone receptors (2012) (19)
- DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia (2015) (19)
- Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites (2020) (19)
- [Pylorus preserving or classical Whipple operation in tumors. Initial clinical results of a prospective randomized study]. (2000) (18)
- 3D Non-Woven Polyvinylidene Fluoride Scaffolds: Fibre Cross Section and Texturizing Patterns Have Impact on Growth of Mesenchymal Stromal Cells (2014) (18)
- Self-Expandable Metal Stents for Persisting Esophageal Variceal Bleeding after Band Ligation or Injection-Therapy: A Retrospective Study (2015) (17)
- Innovative method for quantification of cell-cell adhesion in 96-well plates (2011) (17)
- The zinc-finger protein KCMF1 is overexpressed during pancreatic cancer development and downregulation of KCMF1 inhibits pancreatic cancer development in mice (2010) (16)
- Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis (2020) (16)
- Clinical Perspectives of Mesenchymal Stem Cells (2012) (16)
- Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation (2007) (16)
- Mutations and variants of ONECUT1 in diabetes (2021) (16)
- Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels (2019) (16)
- Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells (2018) (15)
- Imbalance of intermediate filament component keratin 14 contributes to increased stress signalling in epidermolysis bullosa simplex (2013) (15)
- Leukocyte Counts Based on DNA Methylation at Individual Cytosines. (2018) (15)
- Serum after Autologous Transplantation Stimulates Proliferation and Expansion of Human Hematopoietic Progenitor Cells (2011) (14)
- Strongyloides stercoralis: A Rare Cause of Obstructive Duodenal Stenosis (2008) (14)
- DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift (2021) (14)
- PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation (2020) (14)
- Smad – Sp 1 complexes mediate TGF b-induced early transcription of oncogenic Smad 7 in pancreatic cancer cells (2006) (14)
- Fluoro-3-Deoxythymidine ( [ 18 F ]-FLT ) as Positron Emission Tomography Tracer for Imaging Proliferation in a Murine B-Cell Lymphoma Model and in the Human Disease (2003) (14)
- Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis (2018) (13)
- Evidence for a pre-existing telomere deficit in non-clonal hematopoietic stem cells in patients with acute myeloid leukemia (2017) (13)
- Postmortem age estimation via DNA methylation analysis in buccal swabs from corpses in different stages of decomposition—a “proof of principle” study (2020) (13)
- Die Technik der pankreaserhaltenden Duodenektomie (2005) (12)
- Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice (2018) (12)
- Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice (2011) (12)
- Platelet lysates and their role in cell therapy (2014) (12)
- DNA methylation in PRDM8 is indicative for dyskeratosis congenita (2016) (12)
- Zinc deficiency leads to reduced interleukin-2 production by active gene silencing due to enhanced CREMα expression in T cells. (2020) (11)
- Epiplakin Deficiency Aggravates Murine Caerulein-Induced Acute Pancreatitis and Favors the Formation of Acinar Keratin Granules (2014) (11)
- Analysis of apoptosome dysregulation in pancreatic cancer and of its role in chemoresistance (2007) (11)
- Epigenetic clocks may come out of rhythm—implications for the estimation of chronological age in forensic casework (2020) (11)
- Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells (2020) (11)
- DNA-methylation changes in replicative senescence and aging: two sides of the same coin? (2016) (11)
- Targeted methods for epigenetic age predictions in mice (2020) (11)
- Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy (2021) (10)
- Epigenetic quality check - how good are your mesenchymal stromal cells? (2016) (10)
- Murine hematopoietic stem cell reconstitution potential is maintained by osteopontin during aging (2018) (10)
- Two-dimensional polymer-based cultures expand cord blood-derived hematopoietic stem cells and support engraftment of NSG mice. (2013) (9)
- Deciphering the calcitriol-induced transcriptomic response in keratinocytes: presentation of novel target genes. (2013) (9)
- Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns (2021) (9)
- Bone marrow niche and leukemia. (2006) (9)
- MicroRNA expression profiles of serum from patients before and after chemotherapy (2015) (8)
- SERPINE 2 ( Protease Nexin I ) Promotes Extracellular Matrix Production and Local Invasion of Pancreatic Tumors in Vivo 1 (2003) (8)
- Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells (2019) (8)
- Secondary sclerosing cholangitis after chemotherapy with bevacizumab and paclitaxel. (2009) (8)
- [Technique of pancreas-preserving duodenectomy]. (2005) (8)
- The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates. (2022) (8)
- Epigenetic Modifications upon Senescence of Mesenchymal Stem Cells (2016) (8)
- Ex vivo expansion of cord blood‐CD34+ cells using IGFBP2 and Angptl‐5 impairs short‐term lymphoid repopulation in vivo (2013) (8)
- Tracking myeloid malignancies by targeted analysis of successive DNA methylation at neighboring CG dinucleotides (2019) (7)
- [Stent or surgical bypass as palliative therapy in obstructive jaundice]. (2000) (7)
- Endogenously Expressed Antigens Bind Mammalian RNA via Cationic Domains that Enhance Priming of Effector CD8 T Cells by DNA Vaccination (2019) (7)
- REVIEW Heterogeneity of mesenchymal stromal cell preparations (2008) (7)
- Nuclear Factor-k B Is Constitutively Active in C-Cell Carcinoma and Required for RET-induced Transformation 1 (2001) (7)
- iPSC-derived mesenchymal stromal cells are less supportive than primary MSCs for co-culture of hematopoietic progenitor cells (2016) (7)
- The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates (2020) (7)
- Expression of Tumor-mediated CD137 ligand in human colon cancer indicates dual signaling effects (2019) (7)
- Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clustering (2017) (7)
- Association of facial ageing with DNA methylation and epigenetic age predictions (2018) (7)
- Cell fusion enhances mesendodermal differentiation of human induced pluripotent stem cells. (2014) (7)
- Evidence for differences in DNA methylation between Germans and Japanese (2021) (6)
- Chicken or Egg: Is Clonal Hematopoiesis Primarily Caused by Genetic or Epigenetic Aberrations? (2019) (6)
- Mesenchymal Stromal Cells (MSC) (2016) (6)
- MicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells (2015) (6)
- Cell Cluster Sorting in Automated Differentiation of Patient-specific Induced Pluripotent Stem Cells Towards Blood Cells (2022) (6)
- IFN-γ treatment protocol for MHC-Ilo/PD-L1+ pancreatic tumor cells selectively restores their TAP-mediated presentation competence and CD8 T-cell priming potential (2020) (6)
- How to Translate DNA Methylation Biomarkers Into Clinical Practice (2022) (6)
- Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells (2018) (6)
- Selective expansion of the beta-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. (2008) (5)
- Inflammation, Regeneration, and Transformation in the Pancreas: Results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm (2011) (5)
- Elevated β-cell stress levels promote severe diabetes development in mice with MODY4 (2019) (5)
- Onkologische Standardchirurgie des Pankreaskarzinoms (1998) (5)
- Triplex Domain Finder: Detection of Triple Helix Binding Domains in Long Non-Coding RNAs (2015) (5)
- [Surgery of pancreatic carcinoma]. (2000) (5)
- The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function (2019) (5)
- Mesenchymal Stem Cells: An Oversimplified Nomenclature for Extremely Heterogeneous Progenitors (2011) (5)
- Toward Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis. (2022) (4)
- stem cells is a hallmark of cancer Age-dependent DNA methylation of genes that are suppressed in Material Supplemental (2010) (4)
- Studentische Lehre in der Augenheilkunde (2013) (4)
- Functional fingerprinting of human mesenchymal stem cells using high-throughput RNAi screening (2015) (4)
- PANKREAS-KARZINOM : CHIRURGISCHE THERAPIE (1996) (4)
- DNA methylation patterns of replicative senescence are strand-specific and reflect changes in chromatin conformation (2018) (4)
- Über die funktionelle Behandlungsmethode nach Kniescheibenverrenkung (1984) (4)
- A tumor-specific neoepitope expressed in homologous/self or heterologous/viral antigens induced comparable effector CD8+ T-cell responses by DNA vaccination. (2020) (4)
- Cord blood telomere shortening associates with increased gestational age and birth weight in preterm neonates. (2021) (4)
- Vor- und Nachteile der winkelstabilen Plattenosteosynthese (2010) (4)
- Adhesion of Hematopoietic Progenitor Cells to Human Mesenchymal Stromal Cells as a Model for Interaction between Stem Cells and Their Niche. (2006) (3)
- Human Hematopoietic Stem Cells and Leukemic Cells Form Cadherin-Catenin Based Junctional Complexes with Mesenchymal Stromal Cells (2008) (3)
- Cancer Model for Positron Emission Tomography in a Murine Pancreatic-deoxyuridine as Tracer ′ F ] Fluoro-218 Evaluation of 5-[ In Vivo (2001) (3)
- Epigenetic drift during long-term culture of cells in vitro (2018) (3)
- Metabolic Alkalosis, Acute Renal Failure and Epileptic Seizures as Unusual Manifestations of an Upside-Down Stomach (2012) (3)
- The Problem of Appetite Loss After Major Abdominal Surgery (2022) (3)
- Whole-transcriptome gene expression profiling in an epidermolysis bullosa simplex Dowling-Meara model keratinocyte cell line uncovered novel, potential therapeutic targets and affected pathways (2015) (3)
- Experimentelle Untersuchung der Bewegungsabläufe des Kniegelenkes nach transpatellarer Steinmann-Nagelfixation (1986) (2)
- Response to Letter to the Editor: Epigenetic Aging in Osteoporosis (2018) (2)
- Nanoscale biofunctionalization of polymer surfaces by laser treatment for controlled cellular differentiation (2015) (2)
- Epigenetic Biomarkers Are Applicable for Risk Stratification in Myelodysplastic Syndromes (2016) (2)
- Analysis of genome-wide DNA methylation profiles by BeadChip technology. (2013) (2)
- DNA methylation profiling in mummified human remains from the eighteenth-century (2021) (2)
- Leukocyte counts based on site-specific DNA methylation analysis (2017) (2)
- DNA Methylation Changes Upon Senescence are Strand-Specific and Reflect Chromatin Conformation (2019) (2)
- [Pancreatic carcinoma: surgical therapy]. (1996) (2)
- From the ORFeome concept to highly comprehensive, full-genome screening libraries. (2013) (2)
- [A prospective comparison of video colonoscopy and CT colonography in asymptomatic patients screened for colorectal cancer]. (2010) (2)
- Molecular and morphological findings in a sample of oral surgery patients: What can we learn for multivariate concepts for age estimation? (2021) (2)
- Altered DNA methylation at age-associated CpG sites in children with growth disorders: impact on age estimation? (2022) (2)
- Clinical Significance and Therapeutic Potential of the Programmed Death Ligand-1 (PD-L1) and PD-L2 Expression in Human Colorectal Cancer (2017) (2)
- Age-Associated DNA Methylation Signature Reveals Premature Aging In Patients With Aplastic Anemia and Dyskeratosis Congenita Which Correlates With Telomere Shortening (2013) (2)
- Clinical Significance and Therapeutic Potential of the Programmed DeathLigand-1 (PD-L1) and PD-L2 Expression in Human Colorectal Cancer (2017) (2)
- Epigenetic Clocks for Mice Based on Age-Associated Regions That are Conserved Between Mouse Strains and Human (2022) (1)
- Why the impact of mechanical stimuli on stem cells remains a challenge (2018) (1)
- Signaturanalyse in der Datenverarbeitung. Anwendungen und Beispiele. (1983) (1)
- Richtlinien für die Physikalische Therapie nach Schulterverletzungen (1987) (1)
- Das pT4-Pankreaskarzinom: Chirurgische und multimodale Behandlung (2007) (1)
- A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation (2018) (1)
- Chemotropic Neomorphogenesis of Hemodynamically Active Hypervascular Patterns in Hare Skin by a Monocytic Polypeptide Mediator for Blood Vessel Growth (Monocyto-Angiotropin) Promotes Tissue Hyperfunction (Hair Growth) (1985) (1)
- CimpleG: Finding simple CpG methylation signatures (2022) (1)
- Nuclear factor kappa B activation in cerulein pancreatitis (1998) (1)
- Epigenetic biomarkers to track differentiation of pluripotent stem cells (2022) (1)
- Änderungen des Flächenkontaktes im oberen Sprunggelenk nach schrittweiser Verkürzung der Fibula (1986) (1)
- Ergebnisse der Kniescheibenzügelung nach Slocum und Larson (1985) (1)
- HMGB2 Loss Upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering Across Cell Types (2018) (1)
- Genomic and Proteomic Signatures of Human Mesenchymal Stem Cells. (2005) (1)
- Ist die Behandlung der Knöchelfrakturen nach konservativen Gesichtspunkten überholt? (1982) (1)
- Longterm IKK2/NF κB signaling in pancreatic βcells induces immunemediated diabetes mellitus (2013) (1)
- SARS-CoV-2 infects cells of the human exocrine and endocrine pancreas and interferes with beta-cell function (2020) (1)
- THE FUNCTIONAL RELEVANCE OF DNMT3A SPLICE VARIANTS IN HEMATOPOIETIC DIFFERENTIATION (2017) (1)
- Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites (2015) (1)
- Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes (2014) (1)
- Behandlungstrichtlinien und Ergebnisse schwerst offener Unterschenkelbrüche (1984) (1)
- Clinical Potentials of Stem Cells: Hype or Hope? (2006) (1)
- Replicative Senescence-Associated Gene Expression Changes In Human MSPCs Independent of Genomic Variations (2010) (1)
- YAP1 is essential for self-organized differentiation of pluripotent stem cells (2022) (1)
- Pancreatic cancer — Can we do better? (1999) (1)
- Hsp72 overexpression accelerates the recovery from acute pancreatitis (2010) (1)
- Okzipitezervikale fusion bei densmetastasierung (1988) (0)
- Operative Behandlung von Kniescheibenluxationen bei Kindern und Jugendlichen (1988) (0)
- B. Management der Vermögensstruktur (2016) (0)
- Stellenwert der erweiterten Lymphknotendissektion beim Pankreaskarzinom (1998) (0)
- Die Ermüdungsfraktur als Ergebnis vasculärer beziehungsweise metabolischer Vorschäden (1989) (0)
- Okzipitozervikale Fusion bd Densmetastasierung (1988) (0)
- Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells. (2010) (0)
- A. Grundlagen der Finanzwirtschaft der Unternehmung (2016) (0)
- Additional file 2: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- D. Alternativen der Kapitalaufbringung (2016) (0)
- Nachbehandlung frischer operierter Kapsel-Band-Verletzungen des Kniegelenkes (1985) (0)
- Immaterielle Werte in der Finanzanalyse (2006) (0)
- Hematopoietic differentiation of induced pluripotent stem cells is epigenetically incomplete and not enhanced by coculture with mesenchymal stroma cells (2018) (0)
- Additional file 8: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Übungen zur Finanzwirtschaft der Unternehmung (2017) (0)
- Additional file 5: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Die britischen Konservativen im Europäischen Parlament (2007) (0)
- The dark side of hematopoietic stem cell expansion - in vitro culture entails specific DNA-hypermethylation which seems to be relevant for loss of stem cell function (2013) (0)
- Loss of ATM accelerates KrasG12D – induced pancreatic cancer formation (2014) (0)
- Machine learning for optimized individual survival prediction in resectable upper gastrointestinal cancer (2022) (0)
- Bypass surgery for pancreatic carcinoma: Has outcome changed? (1998) (0)
- Loss of ATM increases cancer formation in a mouse model of human pancreatic ductal adenocarcinoma (2012) (0)
- ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Subject Index Vol. 11, 1994 (1994) (0)
- Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation (2022) (0)
- Pancreatic left resection: An underestimated surgical procedure (1998) (0)
- 68 POSTER Sensitivity of a disseminated in vivo model of L363 plasma cell leukaemia against antitumoral compounds sorafenib, bortezomib, and dexamethasone (2008) (0)
- Delayed gastric emptying occurs after both classical and pylorus-preserving whipple procedure (1998) (0)
- DNA methylation changes in hematopoietic development and iPSC-derived model systems (2018) (0)
- Establishment of a Metastasizing Human Cell Line Based Multiple Myeloma Model in Immunodeficient Mice. (2007) (0)
- SCL9 Surgery of Pancreatic Cancer (2000) (0)
- A prospective comparison of video colonoscopy and CT colonography in asymptomatic patients screened for colorectal cancer (2011) (0)
- Epi-Blood-Count: leukocyte differential counts based on DNA methylation levels at individual CpG sites (2017) (0)
- Intraoperative visualisation of pancreatic leakage (ViP): study protocol for an IDEAL Stage I Post Market Clinical Study (2022) (0)
- Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoietic differentiation (2018) (0)
- Subject Index Vol. 77, 2008 (2008) (0)
- Self expandible metal stents in variceal bleeding as the Blakemore-Sengstaken tube of nowadays? – a single institution experience (2014) (0)
- Contents Vol. 77, 2008 (2008) (0)
- Animal Models of Bone Necrosis: An Overview (2014) (0)
- Interaction of Stem Cells and Their Niche: Behavior and Gene Expression Profiles of CD34+/CD38− Cells upon Co-Cultivation with AFT024. (2004) (0)
- Epigenetic Modifications upon Senescence of Mesenchymal Stem Cells (2016) (0)
- Murine hematopoietic stem cell reconstitution potential is maintained by osteopontin during aging (2018) (0)
- Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells (2018) (0)
- Dna methylation of manufactured red blood cells from human induced pluripotent stem cells (2017) (0)
- DNMT3A knockouts in human iPSCs prevent de novo DNA methylation and reveal growth advantage during hematopoietic differentiation (2021) (0)
- DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift (2021) (0)
- DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia (2015) (0)
- Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites (2020) (0)
- Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells (2020) (0)
- A two-scale gene expression landscape for the characterization of in vitro differentiated cells (2014) (0)
- Epigenetic aging clocks in mice and men (2017) (0)
- Implications of long-term culture for mesenchymal stem cells: genetic defects or epigenetic regulation? (2012) (0)
- Epigenetic rejuvenation by partial reprogramming (2023) (0)
- Regulation of Protein kinase D2 by Hsp is crucial for tumour cell-endothelial cell communication in gastrointestinal tumours (2012) (0)
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites (2014) (0)
- New targeted approaches for epigenetic age predictions (2020) (0)
- Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice (2018) (0)
- Epigenetic age-predictions in mice using pyrosequencing, droplet digital PCR or barcoded bisulfite amplicon sequencing (2020) (0)
- Effects of senolytic drugs on human mesenchymal stromal cells (2018) (0)
- Additional file 4: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells (2019) (0)
- Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation (2022) (0)
- LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat (2018) (0)
- Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy (2022) (0)
- Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells (2017) (0)
- Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging (2017) (0)
- DNA methylation aging clocks: challenges and recommendations (2019) (0)
- DNA methylation changes associated with cannabis use and verbal learning performance in adolescents: an exploratory whole genome methylation study (2022) (0)
- Neuropathic pain associated with sodium channel Nav1.7 variant R1150W (2018) (0)
- Human pluripotent stem cell-derived pancreatic ductal organoids to model familial pancreatic cancer in the context of CDKN2a or BRCA2 deficiency (2020) (0)
- Association of facial ageing with DNA methylation and epigenetic age predictions (2018) (0)
- The IKK subunit NEMO is essential for KRAS-induced pancreatic intraepithelial neoplasia (2015) (0)
- Abstract 5616: Activation of CD137/CD137L results in reduced tumor cell proliferation in human colon cancer (2017) (0)
- McCune-Albright syndrome and IPMN formation modelled in GNAS-mutated duct-like organoids derived from human pluripotent stem cells (2020) (0)
- Hematopoietic Progenitors with Slow Divisional Kinetics Give Rise to T Cell Precursors in the Thymus of the SCID Mouse Transplantation Model and Represent the Subset with Primitive Function. (2007) (0)
- Loss of ATM increases pancreatic cancer formation via induction of EMT (2013) (0)
- Regulation der subzellulären Lokalisation von Protein Kinase D2 (PKD2) in gastrointestinalen Tumoren (2005) (0)
- Additional file 1: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Erk-independent Regulation of Growth in Pancreatic Carcinoma via Rap1 (2005) (0)
- Additional file 6: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Evidence for Premature Aging of (Clonal but also) Non-Clonal Hematopoietic Stem Cells in Patients with Acute Myeloid Leukemia (AML) (2014) (0)
- TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration (2023) (0)
- Additional file 7: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Antitumor Activity in a Human Multiple Myeloma (MM) Model Using Sorafenib, Bortezomib, and Dexamethasone Treatment. (2008) (0)
- Maintenance of Osteogenic Differentiation Capacity of MSPC Despite Amplified Proliferation Under Elevated Oxgen Conditions (2012) (0)
- AGI September 40/3 (1999) (0)
- New Therapies of Bone Necrosis (2014) (0)
- 254: AMD3100 Mobilizes a More Primitive Hematopoietic Progenitor Subset from Human Marrow (2008) (0)
- Functional fingerprinting of human mesenchymal stem cells using high-throughput RNAi screening (2015) (0)
- Supplemental Data DNA-Methylation in C 1 R is a Prognostic Biomarker for Acute Myeloid Leukemia (2015) (0)
- LOW ALKALINE PHOSPHATASE ACTIVITY AND IN VIVO CALCIFICATION AFTER IN VITRO CHONDROGENESIS OF SYNOVIUM-DERIVED MESENCHYMAL STEM CELLS (2009) (0)
- Additional file 3: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- N-Cadherin and Cadherin-11 Play Vital Roles in the Cell-Cell Contact between Hematopoietic Progenitor Cells and Mesenchymal Stromal Cells. (2007) (0)
- Decision letter: A whole lifespan mouse multi-tissue DNA methylation clock (2018) (0)
- Molecular approaches for in vitro expansion of human haematopoietic stem and progenitor cells (2017) (0)
- 82: Regulation of initial self-renewing divisions of hematopoietic stem cells by human mesenchymal stromal cells (2007) (0)
- Human Hematopoietic and Mesenchymal Stem Cells Are Interconnected by Cadherin-Catenin Based Junctions. (2007) (0)
- Dissecting Hedgehog signaling in the mesenchymal and epithelial compartment in K-RasG 12 D induced pancreatic neoplasia (2016) (0)
- Overexpression of ErbB2 in the exocrine pancreas does not result in increased proliferation but induces an inflammatory response (2015) (0)
- Morphological characterization of extracellular matrix formation and time dependent regulation MMP's and TIMPS's in TGF-α transgenic mice (1998) (0)
- Characterization of Intercellular Junctional Complexes between Human Hematopoietic and Mesenchymal Stem Cells. (2006) (0)
- An extended gene expression landscape for the characterization and quality control of in vitro differentiated cells (2014) (0)
- Loss of Stromal Caveolin-1 Independently Predicts Poor Disease-Free Survival and Time to Recurrence in Patients with Prostate Cancer (2010) (0)
- Organotypic Epigenetic Signature Predicts Bone and Marrow Niche Forming Capacity of Stromal Progenitors in a Novel Mouse Model in Vivo. (2012) (0)
- Impact of topographic stimuli on the biology of mesenchymal and induced pluripotent stem cells (2017) (0)
- HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer (2015) (0)
- The Hematopoietic Supportive Potential of Human Mesenchymal Stromal Cells Is Associated with Expression of Cadherins. (2006) (0)
- Die chirurgische Therapie bei frischen Kapsel-Bandverletzungen des Kniegelenkes (1984) (0)
- Physikalische Therapie und Nachbehandlung bei Bandverletzungen des Kniegelenkes (1984) (0)
- Achsenfehler nach gedeckter Oberschenkelverriegelungsnagelung (1986) (0)
- Übungsbuch zur Finanzwirtschaft der Unternehmung (2017) (0)
- Allgemeinbildendes Schulwesen in der DDR und in Österreich (2008) (0)
- MPFL-Rekonstruktion und Trochleaplastik – Pathologie und Therapie der patellofemoralen Instabilität (2009) (0)
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What Schools Are Affiliated With Wolfgang Wagner?
Wolfgang Wagner is affiliated with the following schools: