Wolfgang Dr Wurst
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(Suggest an Edit or Addition)Wolfgang Dr Wurst's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. (2017) (1430)
- Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells (2015) (1011)
- Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 (1998) (928)
- Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. (2008) (897)
- Arc/Arg3.1 Is Essential for the Consolidation of Synaptic Plasticity and Memories (2006) (822)
- Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death (1993) (686)
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis (2017) (669)
- The Knockout Mouse Project (2004) (574)
- Neural plate patterning: Upstream and downstream of the isthmic organizer (2001) (547)
- Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. (1994) (525)
- Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function (2004) (479)
- A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice (2009) (465)
- Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress (2003) (444)
- A Mouse for All Reasons (2007) (420)
- Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders (2014) (418)
- Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. (1995) (412)
- Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function (2009) (393)
- Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation* (2009) (388)
- Inducible gene deletion in astroglia and radial glia—A valuable tool for functional and lineage analysis (2006) (381)
- A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains (2013) (370)
- Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development (2005) (362)
- The caudal limit of Otx2 expression positions the isthmic organizer (1999) (344)
- Fate of Midbrain Dopaminergic Neurons Controlled by the Engrailed Genes (2001) (343)
- The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum (2003) (340)
- The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney. (1996) (324)
- Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. (2000) (323)
- Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. (1994) (322)
- Rapamycin extends murine lifespan but has limited effects on aging. (2013) (313)
- The mouse Engrailed-1 gene and ventral limb patterning (1996) (306)
- EphA-Ephrin-A-Mediated β Cell Communication Regulates Insulin Secretion from Pancreatic Islets (2007) (299)
- Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress (2011) (297)
- Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1 (2011) (291)
- The mammalian gene function resource: the international knockout mouse consortium (2012) (277)
- Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases (2010) (275)
- A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo (2006) (271)
- LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool (2011) (264)
- Production of targeted embryonic stem cell clones. (1993) (260)
- Mitochondrial glutathione peroxidase 4 disruption causes male infertility (2009) (260)
- Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. (2007) (258)
- Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity (2007) (248)
- Development of an intein-mediated split–Cas9 system for gene therapy (2015) (243)
- Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. (2008) (235)
- Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain (2004) (230)
- The Nuclear Form of Phospholipid Hydroperoxide Glutathione Peroxidase Is a Protein Thiol Peroxidase Contributing to Sperm Chromatin Stability (2005) (221)
- Enhanced and Delayed Stress-Induced Alcohol Drinking in Mice Lacking Functional CRH1 Receptors (2002) (219)
- A public gene trap resource for mouse functional genomics (2004) (203)
- TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury (2017) (200)
- FGFR1 is independently required in both developing mid‐ and hindbrain for sustained response to isthmic signals (2003) (197)
- Development of dopaminergic neurons in the mammalian brain (2006) (196)
- Introducing the German Mouse Clinic: open access platform for standardized phenotyping (2005) (192)
- The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. (2013) (185)
- Modulation of dendritic differentiation by corticotropin-releasing factor in the developing hippocampus. (2004) (182)
- Genomewide production of multipurpose alleles for the functional analysis of the mouse genome. (2005) (182)
- Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome (2009) (177)
- Prevalence of sexual dimorphism in mammalian phenotypic traits (2017) (177)
- Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. (2013) (176)
- Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6 (2006) (171)
- Regulation of astrocyte inflammatory responses by the Parkinson's disease‐associated gene DJ–1 (2009) (166)
- A role for the EphA family in the topographic targeting of vomeronasal axons. (2001) (162)
- Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells (2000) (157)
- A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome (2003) (156)
- Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization (2001) (153)
- Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis (2017) (152)
- Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. (2007) (150)
- Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling (2011) (147)
- Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region (2004) (147)
- Location and Size of Dopaminergic and Serotonergic Cell Populations Are Controlled by the Position of the Midbrain–Hindbrain Organizer (2003) (147)
- Forebrain CRF1 Modulates Early-Life Stress-Programmed Cognitive Deficits (2011) (147)
- Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides (2013) (146)
- Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain (2003) (145)
- Genetic networks controlling the development of midbrain dopaminergic neurons (2006) (136)
- Functional Annotation of Mouse Genome Sequences (2001) (136)
- Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics (2015) (135)
- The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse (2005) (133)
- Pitchfork regulates primary cilia disassembly and left-right asymmetry. (2010) (131)
- Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity (2019) (130)
- LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum (2007) (129)
- Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss (2013) (128)
- Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior (2008) (127)
- The FTD‐like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism (2017) (127)
- An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. (1996) (127)
- Nephrin TRAP mice lack slit diaphragms and show fibrotic glomeruli and cystic tubular lesions. (2002) (126)
- Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP (2010) (123)
- Extracellular Engrailed Participates in the Topographic Guidance of Retinal Axons In Vivo (2009) (122)
- Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation. (2014) (121)
- Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. (2011) (121)
- A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice. (1995) (120)
- Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon (2008) (116)
- Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo (2008) (116)
- Evolutionarily Conserved Role of Nucleostemin: Controlling Proliferation of Stem/Progenitor Cells during Early Vertebrate Development (2006) (115)
- Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy (2020) (113)
- Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood (2017) (112)
- Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling (2009) (112)
- EUCOMM--the European conditional mouse mutagenesis program. (2007) (110)
- Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference (2007) (109)
- The specific role of histone deacetylase 2 in adult neurogenesis. (2010) (107)
- Creatine improves health and survival of mice (2008) (105)
- Cannabinoid CB1 receptor is dispensable for memory extinction in an appetitively-motivated learning task. (2005) (105)
- Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons (2009) (104)
- A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction (2017) (104)
- The winged helix transcription factor Fkh10 is required for normal development of the inner ear (1998) (104)
- Mouse phenotyping. (2011) (103)
- Regulation of the Hypothalamic-Pituitary-Adrenocortical System in Mice Deficient for CRH Receptors 1 and 2. (2001) (102)
- Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon (2014) (102)
- Hypogonadotropic hypogonadism and peripheral neuropathy in Ebf2-null mice (2003) (101)
- Animal models for arthritis: innovative tools for prevention and treatment (2011) (100)
- Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas (2005) (99)
- The Hsp90 Cochaperone p23 Is Essential for Perinatal Survival (2006) (99)
- A Unilateral Negative Feedback Loop Between miR-200 microRNAs and Sox2/E2F3 Controls Neural Progenitor Cell-Cycle Exit and Differentiation (2012) (98)
- Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons (2011) (98)
- A New Partner for the International Knockout Mouse Consortium (2007) (97)
- Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep (2009) (97)
- Fibroblast Growth Factor Receptors Cooperate to Regulate Neural Progenitor Properties in the Developing Midbrain and Hindbrain (2007) (97)
- Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders (2015) (95)
- Generation and Characterization of dickkopf3 Mutant Mice (2006) (95)
- Erratum: Corrigendum: The European dimension for the mouse genome mutagenesis program (2004) (95)
- Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43* (2014) (94)
- Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss (2017) (92)
- Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin‐releasing hormone signaling (2009) (92)
- Phenotypic annotation of the mouse X chromosome. (2010) (91)
- Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. (2011) (90)
- Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis (2017) (89)
- Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy (2018) (89)
- Getting closer to affective disorders: the role of CRH receptor systems. (2004) (87)
- Early‐life stress‐induced anxiety‐related behavior in adult mice partially requires forebrain corticotropin‐releasing hormone receptor 1 (2012) (87)
- The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans (2018) (87)
- Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice* (2011) (87)
- Systemic first-line phenotyping. (2009) (86)
- Individual Stress Vulnerability Is Predicted by Short-Term Memory and AMPA Receptor Subunit Ratio in the Hippocampus (2010) (86)
- Permutation-validated principal components analysis of microarray data (2002) (83)
- Structural Determinants of the C-terminal Helix-Kink-Helix Motif Essential for Protein Stability and Survival Promoting Activity of DJ-1* (2007) (83)
- Essential roles of BMPR‐IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis (2004) (82)
- Urocortin 3 Modulates Social Discrimination Abilities via Corticotropin-Releasing Hormone Receptor Type 2 (2010) (81)
- A systems medicine research approach for studying alcohol addiction (2013) (81)
- FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis (2018) (80)
- Fgfr1-dependent boundary cells between developing mid- and hindbrain. (2005) (79)
- DJ‐1‐deficient mice show less TH‐positive neurons in the ventral tegmental area and exhibit non‐motoric behavioural impairments (2010) (79)
- Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety (2018) (77)
- The isthmic neuroepithelium is essential for cerebellar midline fusion (2003) (75)
- Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10 (2012) (75)
- Multiple roles of ephrins during the formation of thalamocortical projections: maps and more. (2004) (74)
- The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs (2020) (74)
- MicroRNA-9 controls dendritic development by targeting REST (2014) (74)
- Efficient Isolation of Pure and Functional Mitochondria from Mouse Tissues Using Automated Tissue Disruption and Enrichment with Anti-TOM22 Magnetic Beads (2013) (74)
- Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain (2009) (71)
- Generating conditional knockout mice. (2011) (71)
- Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice (2002) (70)
- Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine (2009) (70)
- Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice (2017) (70)
- Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice. (2011) (70)
- Highly Efficient Targeted Mutagenesis in Mice Using TALENs (2013) (69)
- mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons (2002) (69)
- Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development (2011) (69)
- Expression Analysis of Lrrk1, Lrrk2 and Lrrk2 Splice Variants in Mice (2013) (69)
- Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice (2016) (65)
- MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation. (2015) (65)
- Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb (2012) (65)
- Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia (2012) (64)
- Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice (2011) (64)
- Molecular characterisation of antidepressant effects in the mouse brain using gene expression profiling. (2002) (64)
- Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect (2009) (63)
- Brain-Specific Inactivation of the Crhr1 Gene Inhibits Post-Dependent and Stress-Induced Alcohol Intake, but Does Not Affect Relapse-Like Drinking (2012) (63)
- Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain (2007) (62)
- Selective Activation of the Hypothalamic Vasopressinergic System in Mice Deficient for the Corticotropin-Releasing Hormone Receptor 1 Is Dependent on Glucocorticoids* * This work was supported by the Volkswagen Stiftung (to F.H. and W.W.). (2000) (62)
- The functional annotation of mammalian genomes: the challenge of phenotyping. (2009) (61)
- The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes (2014) (61)
- Gene Expression Profiling Following Maternal Deprivation: Involvement of the Brain Renin-Angiotensin System (2009) (61)
- Pro-Survival Role for Parkinson's Associated Gene DJ-1 Revealed in Trophically Impaired Dopaminergic Neurons (2010) (61)
- An integrated genome research network for studying the genetics of alcohol addiction (2010) (60)
- Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition (2011) (59)
- Miswiring of Limbic Thalamocortical Projections in the Absence of Ephrin-A5 (2002) (59)
- Diversity matters – heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease (2016) (59)
- A comparative phenotypic and genomic analysis of C 57 BL / 6 J and C 57 BL / 6 N mouse strains (2013) (59)
- The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. (2009) (59)
- Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA (2013) (58)
- High-fat diet induced isoform changes of the Parkinson's disease protein DJ-1. (2014) (58)
- Modeling disease mutations by gene targeting in one-cell mouse embryos (2012) (58)
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping (2018) (58)
- Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2. (2001) (57)
- Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System (2012) (57)
- LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4. (2013) (56)
- Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse (2006) (56)
- Coregulation of anterior and posterior mesendodermal development by a hairy-related transcriptional repressor. (2000) (55)
- Sall1, sall2, and sall4 are required for neural tube closure in mice. (2008) (55)
- Disruption of the murine PIASx gene results in reduced testis weight. (2005) (54)
- Shh dependent and independent maintenance of basal midbrain (2009) (53)
- Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility* (2015) (53)
- FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. (2006) (53)
- Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms (2012) (52)
- CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting (2016) (52)
- Dissecting the genetic effect of the CRH system on anxiety and stress-related behaviour. (2005) (52)
- Splinkerette PCR for more efficient characterization of gene trap events (2007) (52)
- Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus (2012) (52)
- Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice (2007) (52)
- Reduced Cerebral Injury in CRH-R1 Deficient Mice after Focal Ischemia: A Potential Link to Microglia and Atrocytes that Express CRH-R1 (2003) (52)
- The REST remodeling complex protects genomic integrity during embryonic neurogenesis (2016) (52)
- "Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour? (2008) (51)
- A protein quality control pathway regulated by linear ubiquitination (2019) (50)
- Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus (2006) (50)
- CRF1 and CRF2 Receptors are Required for Potentiated Startle to Contextual but not Discrete Cues (2009) (50)
- MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention. (2015) (50)
- Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids. (2000) (49)
- Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests (2012) (49)
- Assessing Cognition in Mice (2015) (49)
- Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival (2014) (49)
- Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5‐deficient mice (2004) (49)
- A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons (2010) (49)
- Control of gene editing by manipulation of DNA repair mechanisms (2017) (48)
- A resource of targeted mutant mouse lines for 5,061 genes (2019) (48)
- Visualizing corticotropin‐releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele (2012) (48)
- Srgap3–/– mice present a neurodevelopmental disorder with schizophrenia‐related intermediate phenotypes (2012) (47)
- A robust and reliable non-invasive test for stress responsivity in mice (2014) (47)
- Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments (2014) (46)
- Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics (2020) (46)
- Expression of Fgf receptors 1, 2, and 3 in the developing mid‐ and hindbrain of the mouse (2005) (46)
- Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism (2016) (45)
- A Wnt Signal Regulates Stem Cell Fate and Differentiation in vivo (2007) (45)
- Human and mouse essentiality screens as a resource for disease gene discovery (2019) (45)
- N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: A putative cellular mechanism for quetiapine as antidepressant (2012) (45)
- Regulation of the developing hypothalamic–pituitary–adrenal axis in corticotropin releasing hormone receptor 1-deficient mice (2003) (44)
- Differential mRNA distribution of components of the ERK/MAPK signalling cascade in the adult mouse brain (2007) (44)
- Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability. (2013) (44)
- Expression of CRHR1 and CRHR2 in Mouse Pituitary and Adrenal Gland: Implications for HPA System Regulation. (2001) (44)
- Delayed dopaminergic neuron differentiation in Lrp6 mutant mice (2009) (43)
- A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice (2017) (43)
- Wnt1-regulated genetic networks in midbrain dopaminergic neuron development. (2014) (43)
- Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans (2012) (43)
- Analysis of the rat major histocompatibility system by Southern blot hybridization. (1985) (43)
- Spatial Analysis of Expression Patterns Predicts Genetic Interactions at the Mid-Hindbrain Boundary (2009) (42)
- Aquarius, a novel gene isolated by gene trapping with an RNA‐dependent RNA polymerase motif (1998) (41)
- Specification of midbrain territory (2004) (41)
- Disruption of feeding behavior in CRH receptor I‐deficient mice is dependent on glucocorticoids (2000) (41)
- MAPK Signaling Determines Anxiety in the Juvenile Mouse Brain but Depression-Like Behavior in Adults (2012) (41)
- Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data (2018) (41)
- A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. (2011) (40)
- High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner* (2013) (40)
- Expression of CRHR1 and CRHR2 in mouse pituitary and adrenal gland: implications for HPA system regulation. (2001) (40)
- Pleiotropic effects in Eya3 knockout mice (2008) (40)
- MiR‐34a deficiency accelerates medulloblastoma formation in vivo (2015) (40)
- Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice. (2010) (40)
- Innovations in phenotyping of mouse models in the German Mouse Clinic (2012) (39)
- Screening for novel pattern formation genes using gene trap approaches. (1993) (39)
- Deletion of Glucose Transporter GLUT8 in Mice Increases Locomotor Activity (2008) (38)
- Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos (2014) (38)
- Claudin-12 is not required for blood–brain barrier tight junction function (2019) (38)
- Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice (2009) (38)
- Metformin Supports the Antidiabetic Effect of a Sodium Glucose Cotransporter 2 Inhibitor by Suppressing Endogenous Glucose Production in Diabetic Mice (2014) (38)
- Localization of heat shock protein 70 genes inside the rat major histocompatibility complex close to class III genes (2006) (38)
- Microphthalmia, parkinsonism, and enhanced nociception in Pitx3416insG mice (2010) (38)
- Correction: An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo (2013) (38)
- CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice (2010) (38)
- Cell-based simulation of dynamic expression patterns in the presomitic mesoderm. (2007) (38)
- Tests for Anxiety‐Related Behavior in Mice (2015) (37)
- Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis. (2011) (37)
- TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons (2018) (37)
- Differential disinhibition of the neonatal hypothalamic– pituitary–adrenal axis in brain‐specific CRH receptor 1‐knockout mice (2006) (37)
- Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. (2009) (36)
- Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism. (2017) (36)
- The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions (2020) (36)
- Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality (2017) (35)
- Gene editing in mouse zygotes using the CRISPR/Cas9 system. (2017) (34)
- Activation of ERK/MAPK in the Lateral Amygdala of the Mouse is Required for Acquisition of a Fear-Potentiated Startle response (2009) (34)
- Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality (2005) (34)
- Generation of shRNA transgenic mice. (2009) (34)
- Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency (2017) (34)
- Novel allele of crybb2 in the mouse and its expression in the brain. (2008) (33)
- Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes (2015) (33)
- An induction gene trap for identifying a homeoprotein-regulated locus (2000) (33)
- Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation. (2011) (33)
- RNA interference in mice. (2007) (32)
- Assessing Behavioural Effects of Chronic HPA Axis Activation Using Conditional CRH-Overexpressing Mice (2012) (32)
- Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions (2015) (32)
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- Efficient Generation of Rat Induced Pluripotent Stem Cells Using a Non-Viral Inducible Vector (2013) (32)
- NeuBtracker—imaging neurobehavioral dynamics in freely behaving fish (2017) (31)
- Considerations on genetic and environmental factors that contribute to resistance or sensitivity of mammals including humans to toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds. Part 1: Genetic factors affecting the toxicity of TCDD. (1997) (31)
- Identification of genes required for eye development by high-throughput screening of mouse knockouts (2018) (30)
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- Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation (2016) (30)
- Urocortin 2 modulates aspects of social behaviour in mice (2012) (30)
- Erratum: Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis (Neuron (2017) 93(3) (560–573.e6) (S089662731630959X), (10.1016/j.neuron.2016.12.017)) (2017) (30)
- Enhanced gene trapping in mouse embryonic stem cells (2008) (30)
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- Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors (2015) (27)
- The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse (2017) (27)
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- Serotonin Hyperinnervation Abolishes Seizure Susceptibility in Otx2 Conditional Mutant Mice (2008) (27)
- Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse (2015) (27)
- The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. (2007) (26)
- Expression Profiling Identifies the CRH/CRH-R1 System as a Modulator of Neurovascular Gene Activity (2007) (26)
- cGMP-dependent protein kinase I, the circadian clock, sleep and learning (2009) (26)
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- Meis1: effects on motor phenotypes and the sensorimotor system in mice (2017) (25)
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- HIC2 Is a Novel Dosage-Dependent Regulator of Cardiac Development Located Within the Distal 22q11 Deletion Syndrome Region (2014) (23)
- Gene and enhancer trapping: mutagenic strategies for developmental studies. (1993) (23)
- Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception (2018) (23)
- MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy (2014) (22)
- Expression domains of murine ephrin-A5 in the pituitary and hypothalamus (2000) (21)
- Expression of neurochondrin in the developing and adult mouse brain (2004) (21)
- Molecular characterization, structure and developmental expression of Megane bHLH factor. (2006) (21)
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- Targeted mutagenesis of Lis 1 disrupts cortical development and LIS 1 homodimerization. (2001) (20)
- Pleiotropic Functions for Transcription Factor Zscan10 (2014) (20)
- CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion (2020) (20)
- Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes (2009) (20)
- High-throughput trapping of secretory pathway genes in mouse embryonic stem cells (2006) (20)
- Sharpening of expression domains induced by transcription and microRNA regulation within a spatio-temporal model of mid-hindbrain boundary formation (2013) (19)
- Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic (2017) (19)
- The Parkinson’s disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4 (2019) (19)
- Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons (2016) (19)
- Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression (2016) (19)
- Novel caspase‐suicide proteins for tamoxifen‐inducible apoptosis (2008) (19)
- PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing (2019) (19)
- High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains (2014) (19)
- A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene. (2019) (18)
- Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3 (2019) (18)
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- A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease (2020) (18)
- Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice (2016) (17)
- Acute stress regulation of neuroplasticity genes in mouse hippocampus CA3 area — Possible novel signalling pathways (2008) (17)
- Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo (2011) (17)
- ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis (2017) (17)
- Cytotoxic T lymphocytes of the rat are predominantly restricted by RTL1.A and Not RT1.C-determined major histocompatibility class I antigens (2004) (16)
- Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model (2017) (16)
- Functional genomics by gene-trapping in embryonic stem cells. (2002) (16)
- FGF/FGFR2 Signaling Regulates the Generation and Correct Positioning of Bergmann Glia Cells in the Developing Mouse Cerebellum (2014) (16)
- Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including Amyloid beta Precursor Protein (2010) (16)
- Sox2 controls Schwann cell self-organization through fibronectin fibrillogenesis (2020) (16)
- Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress (2008) (15)
- Genetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue Attenuation (2018) (15)
- Gene knockdown in the mouse through RNAi. (2010) (15)
- Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system (2008) (15)
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- Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1 (2019) (14)
- Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1 (2018) (14)
- Genome editing for Duchenne muscular dystrophy: a glimpse of the future? (2021) (14)
- Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons (2019) (13)
- Expression of a novel mouse gene ‘mbFZb’ in distinct regions of the developing nervous system and the adult brain (2001) (13)
- Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions (2009) (13)
- CRISPR-Cas9 enables conditional mutagenesis of challenging loci (2016) (13)
- miR‐191 modulates B‐cell development and targets transcription factors E2A, Foxp1, and Egr1 (2018) (13)
- Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice (2016) (13)
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms (2016) (13)
- Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function (2007) (13)
- Forced expression of platelet-derived growth factor B in the mouse cerebellar primordium changes cell migration during midline fusion and causes cerebellar ectopia (2004) (13)
- Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility (2014) (13)
- Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling (2020) (12)
- A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes (2020) (12)
- Fgf15 regulates thalamic development by controlling the expression of proneural genes (2016) (12)
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- Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density (2020) (12)
- Immunology, Signal Transduction, and Behavior in Hypothalamic–Pituitary–Adrenal Axis‐related Genetic Mouse Models (2009) (12)
- Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping (2021) (12)
- Alpha-synuclein fragments trigger distinct aggregation pathways (2020) (12)
- Analysis of locomotor behavior in the German Mouse Clinic (2017) (12)
- Resources for proteomics in mouse embryonic stem cells (2011) (12)
- Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice (2018) (11)
- Creatine improves health and survival in mice (2007) (11)
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- Characterization of a class Ib gene of the rat major histocompatibility complex (2004) (10)
- Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency (2019) (10)
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- Periphilin is strongly expressed in the murine nervous system and is indispensable for murine development (2009) (10)
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- Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis (2015) (10)
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- Mammalian VPS45 orchestrates trafficking through the endosomal system. (2020) (9)
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- Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice (2017) (9)
- Targeted Disruption of the Mouse Npal3 Gene Leads to Deficits in Behavior, Increased IgE Levels, and Impaired Lung Function (2009) (8)
- Fast Synchronization of Ultradian Oscillators Controlled by Delta-Notch Signaling with Cis-Inhibition (2014) (8)
- Erratum: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells (2018) (8)
- Genetic mapping of C4 and Bf complement genes in the rat major histocompatibility complex (2004) (8)
- CRHR1-dependent effects on protein expression and posttranslational modification in AtT-20 cells (2008) (8)
- The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations (2016) (8)
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- A mutant rat major histocompatibility haplotype showing a large deletion of class I sequences (2006) (8)
- Local Knockdown of ERK2 in the Adult Mouse Brain Via Adeno-Associated Virus-Mediated RNA Interference (2008) (7)
- Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice (2022) (7)
- Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models (2010) (7)
- In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria. (2019) (7)
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- CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion (2021) (6)
- Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease (2022) (6)
- Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples. (2013) (6)
- The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence (2016) (6)
- Amygdala and neocortex: common origins and shared mechanisms (2007) (6)
- Corrigendum: High-throughput discovery of novel developmental phenotypes (2017) (6)
- A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons (2020) (6)
- Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes (2021) (6)
- Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity (2015) (6)
- Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines. (2012) (6)
- Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (6)
- Reversible and tissue‐specific activation of MAP kinase signaling by tamoxifen in brafV637ERT2 mice (2013) (6)
- Genetic control of rodent midbrain dopaminergic neuron development in the light of human disease. (2008) (6)
- Ectopic Dopaminergic Progenitor Cells from En1 +/Otx2lacZ Transgenic Mice Survive and Functionally Reinnervate the Striatum Following Transplantation in a Rat Model of Parkinson's Disease (2010) (6)
- Soft windowing application to improve analysis of high-throughput phenotyping data (2019) (6)
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- Genome Editing in Mice Using TALE Nucleases. (2016) (5)
- Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation (2022) (5)
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- Mouse geneticists need European strategy too (2005) (4)
- Genetic Models of Parkinson’s Disease (2011) (4)
- Susceptibility to diet induced obesity at thermoneutral conditions is independent of UCP1 (2021) (4)
- Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1. (2021) (4)
- Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons (2022) (4)
- Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development (2016) (4)
- The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans (2018) (4)
- Pig models for Duchenne muscular dystrophy – from disease mechanisms to validation of new diagnostic and therapeutic concepts (2022) (4)
- CIN 85 regulates dopamine receptor endocytosis and governs behavior in mice (2010) (4)
- Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation (2016) (4)
- Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality (2005) (3)
- Faculty Opinions recommendation of Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. (2005) (3)
- Chapter 5 - "Parkinson's disease - A role of non-enzymatic posttranslational modifications in disease onset and progression?" (2022) (3)
- Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain (2022) (3)
- iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression (2021) (3)
- New mouse models for the analysis of cGMP signalling (2007) (3)
- Products of the Parkinson’s-disease related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival (2014) (3)
- Simple Derivation of Transgene-Free iPS Cells by a Dual Recombinase Approach (2014) (3)
- Author Correction: Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception (2018) (3)
- Corticotropin-releasing hormone regulates common target genes with divergent functions in corticotrope and neuronal cells (2012) (3)
- The production of 4,182 mouse lines identifies experimental and biological variables impacting Cas9-mediated mutant mouse line production (2021) (3)
- Analysis of a nonclassical class I gene of the rat major histocompatibility complex. (1990) (3)
- TALENs : Methods and Protocols (2016) (3)
- Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy. (2015) (3)
- Animal Models Are Valid to Uncover Disease Mechanisms (2016) (3)
- Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons (2021) (2)
- Mutant non-coding RNA resource in mouse embryonic stem cells (2021) (2)
- Control of gene editing by manipulation of DNA repair mechanisms (2017) (2)
- Mouse Genetics and Metabolic Mouse Phenotyping (2012) (2)
- Direct Cloning of Isogenic Murine DNA in Yeast and Relevance of Isogenicity for Targeting in Embryonic Stem Cells (2013) (2)
- Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics (2020) (2)
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- The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes beneficial microglial functions (2020) (2)
- A Customizable Protocol for String Assembly gRNA Cloning (STAgR). (2018) (2)
- Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism (2021) (2)
- Mouse mutagenesis and gene function (2005) (2)
- Gene Editing in One‐Cell Embryos by Zinc‐Finger and TAL Nucleases (2012) (2)
- Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk (2021) (2)
- Addressing in vivo functions of urocortin III, a novel member of the CRH family of neuropeptides (2004) (2)
- Site-specific overexpression of corticotropin-releasing hormone (CRH) in the mouse brain - modelling central CRH system hyperactivity (2005) (2)
- Characterising a homozygous two‐exon deletion in UQCRH: comparing human and mouse phenotypes (2021) (2)
- Mouse IDGenes: a reference database for genetic interactions in the developing mouse brain (2014) (2)
- Innovations in phenotyping of mouse models in the German Mouse Clinic (2012) (1)
- Conditional overexpression of corticotropin-releasing hormone in mice, an animal model for understanding the development of corticotropin-releasing hormone-mediated brain pathology (2007) (1)
- Genotyping gene-trap mutant mice by real-time PCR (2002) (1)
- Redundant functions of Fgfr1, Fgfr2 and Fgfr3 in the development of the mid- and hindbrain (2006) (1)
- Analysis of the major histocompatibility genes that control susceptibility to diabetes mellitus in the BB rat. (1989) (1)
- Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo (2018) (1)
- Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein (2022) (1)
- An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo (2013) (1)
- Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function (2013) (1)
- Gene expression profiling reveals corticotropin-releasing hormone (CRH) dependent signaling pathways (2005) (1)
- Genetic Control of Meso-diencephalic Dopaminergic Neuron Development in Rodents (2009) (1)
- Genetic pathways controlling midbrain dopaminergic neuron development in vivo (2008) (1)
- Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests (2012) (1)
- Method Creation of targeted genomic deletions using TALEN or CRISPR / Cas nuclease pairs in one-cell mouse embryos (2015) (1)
- Limbic Crhr1 mediates anxiety-related behaviour and is required for hormonal adaptation to stress (2004) (1)
- Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome (2022) (1)
- Canonical Wnt-signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons (2020) (1)
- In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system (2013) (1)
- A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains (2013) (1)
- Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans (2020) (1)
- A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse (2021) (1)
- Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts (2019) (1)
- Pitchfork regulates primary cilia disassembly (2009) (1)
- Role of CRF-R1 and CRF-R2 receptors in unconditioned and conditioned fear-induced increases in startle (2007) (1)
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- Disruption of feeding behaviour in corticotropin releasing hormone type-1 receptor (CRHR1) deficient mice is dependent on glucocorticoids (2000) (0)
- Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes (2015) (0)
- SrGAP3/MEGAP knockout mice express schizophrenia-related endophenotypes (2011) (0)
- Comparison of gene expression patterns in murine blood and brain after chronic paroxetine treatment (2007) (0)
- Parkin: A stress-protective E3 ubiquitin ligase maintaining mitochondrial integrity (2012) (0)
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- Local Knockdown of ERK2 in the Adult Mouse Brain Via Adeno-Associated Virus-Mediated RNA Interference (2008) (0)
- Fgf9Y162C Mutation Alters Information Processing and Social Memory in Mice (2017) (0)
- Directed Gene Trapping in Embryonic Stem Cells (1996) (0)
- A method for identifying target genes of transcription factors (1997) (0)
- Limbic NF-KB signalling controls stress-induced anxiety and antidepressant effects independently of the HPA axis (2010) (0)
- Cell type specific expression of tumor necrosis factor-a in the CNS and pituitary of transgenic mice (1998) (0)
- Author response: MicroRNA-9 controls dendritic development by targeting REST (2014) (0)
- Human and mouse essentiality screens as a resource for disease gene discovery (2020) (0)
- Faculty Opinions recommendation of Mutagenic insertion and chromosome engineering resource (MICER). (2004) (0)
- Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice (2018) (0)
- Non-Redundant Functions of Thioredoxin Reductase 1 and 2 (2006) (0)
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- Metabolic phenotyping of the mouse mutant line Ftotm1b (2012) (0)
- A mouse model for FTD-like syndrome due to TREM2 mutations (2016) (0)
- Viable EdnraY129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation (2016) (0)
- PINK1 Regulates Dopamine and Lipids at Mitochondria to Maintain Synapses and Neuronal Function (2019) (0)
- Functional and molecular genetic analysis of a group of rat class I major histocompatibility genes which might be homologous to H-2Qa. (1985) (0)
- Publisher Correction: Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics (2020) (0)
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- A novel family of repeat sequences in the mouse genome responsive to retinoic acid (1996) (0)
- Author response for "Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans" (2020) (0)
- Telomere Shortening Abrogates Dentate Gyrus Neurogenesis But Improves Alzheimer'S Disease Progression In Mice (2009) (0)
- The ubiquitin-like pathway neddylation controls adipocyte differentiation, obesity and metabolism (2016) (0)
- Lifetime Study in mice: radiation-induced cataract (2015) (0)
- A mouse model for human-specific changes in FOXP2, a gene important for speech and language. (2007) (0)
- Generation of a CRH-Cre mouse line to analyze the CRH system (2007) (0)
- P30 EUROPEAN COMPREHENSIVE FIRST-LINE PHENOTYPING PROTOCOL FOR MICE: CROSS-LABORATORY VALIDATION OF A PRIMARY BEHAVIOURAL SCREEN TEST BATTERY (2004) (0)
- Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms (2016) (0)
- A Tauopathy hiPSC model for MAPT alternative splicing investigation (2021) (0)
- CRH Acts Anxiolytic by Modulating Dopamine Release through a Subset of GABAergic Long-range Projection Neurons (2015) (0)
- Neddylation, a new post-translational modification, controls dendrite and synapse development (2012) (0)
- Summary Otx 2 regulates the extent , identity and fate of neuronal progenitor domains in the ventral midbrain (2004) (0)
- Prepulse inhibition and auditory startle response in meis1 knock-out mice (2015) (0)
- Genome-wide screening reveals the genetic basis of mammalian embryonic eye development (2023) (0)
- The P2X7-Receptor – A novel candidate-gene for depression (2005) (0)
- Stress-induced gene expression in the paraventricular nucleus of hypothalamus in the mouse strains DBA/2J and C57BL/6J – potential signalling pathways involved (2009) (0)
- Faculty Opinions recommendation of Cre-lox-regulated conditional RNA interference from transgenes. (2004) (0)
- Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity (2014) (0)
- Functional Analysis of the Mammalian Genome by Large Scale Gene Trap Mutagenesis (2005) (0)
- NSUN 2-mediated cytosine-5 RNA methylation (2014) (0)
- P2RX7-a susceptibility gene for mood disorders? (2014) (0)
- Erratum: Splinkerette PCR for more efficient characterization of gene trap events (2007) (0)
- 6 The role of mouse engrailed genes in mid- hindbrain development (1996) (0)
- A bipolar disorder-associated single nucleotide polymorphism alters protein function and mouse behavior (2022) (0)
- Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity (2019) (0)
- Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System. (2023) (0)
- Analysis of Urocortin 2 overexpressing mice (2005) (0)
- Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy (2020) (0)
- Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice (2016) (0)
- Central nervous system disorders (2006) (0)
- Gene trap cassette for a directed and undirected conditional gene inactivation (2005) (0)
- A rationale for considering heart/brain axis control in neuropsychiatric disease. (2022) (0)
- Mammalian VPS 45 orchestrates trafficking through the endosomal system Tracking no : BLD-2020-006871 R 2 (2020) (0)
- Creating Coordination in the Cerebellum Catania, 2–4 October 2003 (2004) (0)
- ALCOHOL DRINKING AND WITHDRAWAL IN MICE LACKING A FUNCTIONAL CRH RECEPTOR 1 (1998) (0)
- Fusion protein comprising a CASPASEDOMÆNE AND A NUKLÆRHORMONRECEPTORBINDINGSDOMÆNE AND METHODS AND USES THEREOF (2008) (0)
- A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction (2017) (0)
- Fgf15 regulates thalamic development by controlling the expression of proneural genes (2015) (0)
- The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions (2020) (0)
- Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk (2018) (0)
- Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection (2021) (0)
- Role of Pink1 in Parkinson's Disease and Mitochondrial Function: Pink1 Regulates Complex I Activity (2010) (0)
- Implication of FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT) (2023) (0)
- 03-P066 Shh dependent and independent maintenance of basal midbrain (2009) (0)
- P.2.09 Limbic Crhr1 mediates anxiety-related behaviour and is required for hormonal adaptation to stress (2004) (0)
- Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain (2018) (0)
- High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains (2014) (0)
- Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema (2017) (0)
- Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain (2023) (0)
- Author Correction: EMPReSS: standardized phenotype screens for functional annotation of the mouse genome (2022) (0)
- ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis (2017) (0)
- Corrigendum to “Regulation of the developing hypothalamic–pituitary–adrenal axis in corticotropin releasing hormone receptor 1-deficient mice” [Neuroscience 119 (2003) 589–595]☆ (2005) (0)
- Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 43 (2003) (0)
- CRHR-1 signalling inhibits AMPA-receptor internalisation (2005) (0)
- Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception (2018) (0)
- Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice (2017) (0)
- Towards brain-specific functions of histone deacetylases (HDACs) using genetic mouse models (2011) (0)
- Gene expression profi ling following maternal deprivation : involvement of the brain renin-angiotensin system (2009) (0)
- Fusion protein comprising a domain Caspase and a binding domain of nuclear hormone receptor and methods and uses thereof (2008) (0)
- Impact of IVC housing on emotionality and fear learning in male C 3 H and B 6 J mice (2006) (0)
- Home appliance sealing unit (2007) (0)
- 12-P003 Gata2 is a postmitotic selector gene for GABAergic neurons in the midbrain (2009) (0)
- Abstract 1117: Investigating the role of PTEN-induced kinase 1 in cancer development and pathogenesis (2012) (0)
- Diet-induced and mono-genetic obesity alter (2015) (0)
- Lifetime Study in mice: 24 months follow up after low doses of ionizing radiation with Scheimpflug imaging and OCT (2016) (0)
- Synphilin-1: generation of conditional knock-out mice (2007) (0)
- P370 CHOLESTATIC Abcb4-DEFICIENT MICE REVEAL DEPRESSION/ANXIETY-LIKE BEHAVIOR (2014) (0)
- Mapping of the midbrain dopaminergic system during development of the chicken embryo reveals evolutionary differences between birds and mammals (2006) (0)
- Dissecting CRHR1-mediated pathways via microarray technology (2007) (0)
- Neuroendocrine regulation in mice deficient for the corticotropin-releasing hormone receptor 1 (CRHR1): activation of the vasopressinergic system and involvement of CRHR1 in adrenocortical function (2000) (0)
- Generation of Conventional and Inducible Cre Mouse Lines Specific for the Adrenal Cortex (2004) (0)
- Functional validation of P2RX7 as a susceptibility marker for depression using humanized mouse mutants (2009) (0)
- Current in Cultured Hippocampal Neurons NRSF Causes cAMP-Sensitive Suppression of Sodium (2015) (0)
- SERF deletion modifies amyloid aggregation in a mouse model of Alzheimer’s disease (2022) (0)
- Erratum (2009) (0)
- Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health (2022) (0)
- Genomewide targeting of secreted and transmembrane proteins using the secretory gene trap U3Ceo (2004) (0)
- The Deep Genome Project (2020) (0)
- CENTRAL CORTICOTROPIN-RELEASING HORMONE OVEREXPRESSION ENHANCES REM SLEEP IN CONDITIONAL TRANSGENIC MICE (2009) (0)
- Disease-oriented Genome Networks Diseases of the Nervous System Network : Systematic Gene Identification and Functional Analyses in Common CNS Disorders Project : Animal Models for Parkinson Disease (2005) (0)
- Genfældekassetter to random and targeted conditioned gene inactivation (2005) (0)
- Identification of ocular regulatory functions of core histone variant H3.2. (2022) (0)
- The Parkinson’s disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4 (2019) (0)
- A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes (2020) (0)
- Molecular mechanisms controlling the development of dopaminergic and noradrenergic neurons (2005) (0)
- Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease (2011) (0)
- Author response: The REST remodeling complex protects genomic integrity during embryonic neurogenesis (2015) (0)
- Genes et proteines medane (2002) (0)
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping (2018) (0)
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What Schools Are Affiliated With Wolfgang Dr Wurst?
Wolfgang Dr Wurst is affiliated with the following schools:
