Wolfram Goessling
#114,958
Most Influential Person Now
Physician-scientist who specializes in oncology and gastroenterology
Wolfram Goessling's AcademicInfluence.com Rankings
Wolfram Goesslingphilosophy Degrees
Philosophy
#11599
World Rank
#16006
Historical Rank
Logic
#8406
World Rank
#10514
Historical Rank
Download Badge
Philosophy
Wolfram Goessling's Degrees
- Doctorate Medicine University of Vienna
- PhD Genetics University of Vienna
Why Is Wolfram Goessling Influential?
(Suggest an Edit or Addition)According to Wikipedia, Wolfram Goessling is a physician-scientist who specializes in oncology and gastroenterology. He is the Robert H. Ebert Professor of Medicine at Harvard Medical School and Chief of the Division of Gastroenterology at Massachusetts General Hospital. Goessling is also involved in the Harvard–MIT Program of Health Sciences and Technology , where he is co-director with Emery N. Brown.
Wolfram Goessling's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transparent adult zebrafish as a tool for in vivo transplantation analysis. (2008) (1135)
- Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis (2007) (1084)
- The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML (2010) (732)
- Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration (2009) (671)
- β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis (2012) (557)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
- Hematopoietic Stem Cell Development Is Dependent on Blood Flow (2009) (399)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Mitochondrial dysfunction remodels one-carbon metabolism in human cells (2015) (324)
- Hypoxia as a therapy for mitochondrial disease (2016) (321)
- Effects of RAS on the genesis of embryonal rhabdomyosarcoma. (2007) (319)
- Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. (2008) (310)
- Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. (2013) (291)
- β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis (2013) (268)
- Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. (2011) (266)
- Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis (2015) (247)
- Identification of small molecules for human hepatocyte expansion and iPS differentiation (2013) (237)
- APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. (2008) (189)
- Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function (2012) (180)
- Zebrafish: an important tool for liver disease research. (2015) (174)
- Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth (2016) (144)
- PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury (2010) (142)
- Unconjugated Bilirubin Exhibits Spontaneous Diffusion through Model Lipid Bilayers and Native Hepatocyte Membranes* (1999) (139)
- Mutation mapping and identification by whole-genome sequencing (2012) (129)
- New waves of discovery: modeling cancer in zebrafish. (2007) (122)
- Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function (2011) (117)
- Genome-wide association study of kidney function decline in individuals of European descent (2014) (114)
- Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation (2016) (100)
- Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. (2013) (98)
- Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors (2007) (91)
- Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production (2016) (87)
- SCFβ-TRCP suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2 (2012) (78)
- Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. (2011) (69)
- Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. (2019) (65)
- Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth (2018) (64)
- Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling (2008) (63)
- Kinetics of Bilirubin Transfer between Serum Albumin and Membrane Vesicles (1995) (55)
- The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. (2016) (50)
- YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. (2020) (48)
- Role of apolipoprotein D in the transport of bilirubin in plasma. (2000) (47)
- Repairing quite swimmingly: advances in regenerative medicine using zebrafish (2014) (47)
- Systematic VCP-UBXD Adaptor Network Proteomics Identifies a Role for UBXN10 in Regulating Ciliogenesis (2015) (46)
- Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. (2014) (45)
- SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. (2017) (44)
- Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish (2013) (43)
- S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury. (2014) (42)
- Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis (2016) (39)
- Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. (2012) (39)
- Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. (2014) (39)
- Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer (2019) (38)
- The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration. (2015) (37)
- Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. (2020) (37)
- ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning (2015) (36)
- Mechanism of hepatocellular uptake of albumin-bound bilirubin. (2000) (36)
- Cannabinoid receptor signaling regulates liver development and metabolism (2016) (36)
- Topoisomerase IIα Is Required for Embryonic Development and Liver Regeneration in Zebrafish (2009) (36)
- Multicenter phase II study of tivozanib (AV-951) and everolimus (RAD001) for patients with refractory, metastatic colorectal cancer. (2013) (35)
- Membrane lipid composition and vesicle size modulate bilirubin intermembrane transfer. Evidence for membrane-directed trafficking of bilirubin in the hepatocyte. (1994) (35)
- The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. (2017) (34)
- PTGER2 Overexpression in Colorectal Cancer Is Associated with Microsatellite Instability, Independent of CpG Island Methylator Phenotype (2010) (33)
- Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development (2013) (31)
- There Is Something Fishy About Liver Cancer: Zebrafish Models of Hepatocellular Carcinoma (2019) (29)
- Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair (2020) (29)
- Increased liver chemistry in an asymptomatic patient. (2005) (28)
- Tfap2a is a novel gatekeeper of nephron differentiation during kidney development (2019) (28)
- Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching. (2001) (27)
- Macrophages in Zebrafish Models of Liver Diseases (2019) (27)
- Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin. Implications for the intracellular transport of nonsubstrate ligands in hepatocytes. (1995) (26)
- Cannabinoid Receptor‐2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P‐Selectin Activity (2015) (25)
- Functional compensation precedes recovery of tissue mass following acute liver injury (2020) (25)
- Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. (2016) (24)
- Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy (2021) (23)
- FT1050 (16,16-dimethyl Prostaglandin E2)-Enhanced Umbilical Cord Blood Accelerates Hematopoietic Engraftment After Reduced Intensity Conditioning and Double Umbilical Cord Blood Transplantation (2011) (19)
- Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation (2015) (19)
- An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery (2018) (19)
- Correction: Corrigendum: Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis (2016) (18)
- Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease. (2006) (16)
- Intracellular transport of small hydrophobic compounds by the hepatocyte. (1996) (15)
- Endoderm specification and liver development. (2016) (15)
- Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood (2020) (15)
- Learning During and From a Crisis: The Student-Led Development of a COVID-19 Curriculum. (2020) (14)
- Hematopoietic stem cell development: using the zebrafish to identify the signaling networks and physical forces regulating hematopoiesis. (2011) (14)
- Endoderm specification, liver development, and regeneration. (2011) (12)
- A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer (2020) (11)
- Clinicopathological findings in patients with COVID‐19‐associated ischaemic enterocolitis (2021) (10)
- Multicenter phase Ib/II study of everolimus (RAD001) and tivozanib (AV-951) in patients with refractory, metastatic colorectal cancer. (2012) (10)
- The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function (2021) (9)
- Hepatic Nervous System in Development, Regeneration, and Disease (2021) (9)
- Sequencing of LRP2 reveals multiple rare variants associated with urinary trefoil factor-3. (2014) (9)
- Repairing quite swimmingly: advances in regenerative medicine using zebrafish (2014) (8)
- Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer. (2016) (6)
- Previews. NOTCHing an arrow at cord blood: translating stem cell knowledge into clinical practice. (2010) (6)
- Prostaglandin E 2 enhances engraftment of human cord blood stem cells and shows long-term safety in preclinical non-human primate transplant models (2017) (6)
- Estrogen Acts Through Estrogen Receptor 2b to Regulate Hepatobiliary Fate During Vertebrate Development (2020) (5)
- Nature and nurture: Environmental toxins and biliary atresia (2016) (5)
- Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity (2020) (5)
- A phase II clinical trial of ganetespib (STA-9090) in previously treated patients with advanced esophagogastric cancers. (2013) (5)
- osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2 (2022) (5)
- A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization (2019) (5)
- Regenerative biology: Take the brakes off for liver repair (2014) (4)
- Prospective Evaluation of Malignancy in 17,708 Patients Randomized to Ezetimibe Versus Placebo (2020) (4)
- β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes. (2009) (4)
- Partial Hepatectomy in Adult Zebrafish. (2021) (3)
- The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity (2020) (3)
- Deciphering hepatocellular carcinoma: from bench to bedside and back. (2009) (3)
- Ex Vivo Treatment of Hematopoietic Stem Cells With 16,16-Dimethyl Prostaglandin E2 (FT1050) Improves Engraftment and Hematopoietic Reconstitution (2011) (3)
- Hepatic stellate cells and cirrhosis: Fishing for cures (2012) (3)
- Genome-wide association study of kidney function decline in individuals of European descent: the CKDGen Consortium. (2015) (3)
- Hematopoietic Stem Cell Development Is Dependent on Blood Flow and Nitric Oxide Signaling (2008) (2)
- Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis. (2006) (2)
- Liver Regeneration in Zebrafish (2015) (2)
- Live imaging defines the dynamics and molecular basis of in vivo mitophagy (2020) (2)
- Estrogen Receptors 1 and 2 Have Stage-Specific Effects on Hematopoietic Stem Cell Regulation In Zebrafish. (2010) (2)
- The cationic amino acid exporter Slc7a7 is induced and vital in tissue macrophages with sustained efferocytic activity. (2020) (2)
- Mo1784 Engineering the Microenvironment of Differentiating IPS Derived Hepatocyte-Like Cells Enables Acquisition of an Adult Phenotype (2013) (2)
- Haematopoietic stem cells show their true colours (2016) (2)
- Planning for municipal solid waste management (1972) (2)
- Biliary epithelial cells are facultative liver stem cells during liver regeneration in adult zebrafish (2023) (1)
- The cationic amino acid exporter Slc7a7 is vital for and induced in tissue macrophages with sustained efferocytic activity (2020) (1)
- EnaBILEing Growth in the Fetal Liver. (2016) (1)
- 17beta-estradiol has a biphasic effect on the formation of hematopoietic stem cells (2013) (1)
- Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy (2020) (1)
- Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function. (2021) (1)
- Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development (2019) (1)
- Amebic liver abscess (2002) (1)
- osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2 (2020) (1)
- Hematopoietic Stem Cell Formation in Zebrafish Is Regulated in a Temporally Distinct Manner by Estrogen Receptor 2 (2011) (1)
- Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy (2020) (1)
- Metabolism-Induced Reactive Oxygen Species and Hif1α-Mediated Gene Regulation Control the Timing and Magnitude of Hematopoietic Stem Cell Induction (2011) (1)
- Embryonic alcohol exposure disrupts the ubiquitin-proteasome system (2022) (1)
- Tfap2a is a novel gatekeeper of differentiation in renal progenitors during kidney development (2018) (1)
- Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment. (2007) (1)
- Tu2049 Hydrogen Sulfide (H2S) Regulates Liver Development and Protects From Acetaminophen (APAP)-Induced Liver Injury in Zebrafish (2013) (1)
- Abstract 4272: Mutations inRABL3alter RAS prenylation and are associated with hereditary pancreatic cancer (2017) (1)
- Position Is Destiny: Metabolism and Cell Identity. (2019) (1)
- Genetic Interaction between PGE2 and the Wnt/β-Catenin Signaling Pathway Regulates Definitive HSC Development and Homeostasis. (2007) (1)
- INVESTIGATING THE ROLE OF EZH1 IN DEVELOPMENTAL HEMATOPOIESIS (2019) (1)
- Hepatobiliary Differentiation: Principles from Embryonic Liver Development (2020) (1)
- A protocol for partial hepatectomy in adult zebrafish (2021) (1)
- Fr397 MATHEMATICAL MODELING OF ALT AND AST TRAJECTORIES ENABLES EARLY RECOGNITION OF LIVER INJURY RESOLUTION AND PREDICTS RESPONSE TO THERAPY IN AUTOIMMUNE HEPATITIS (2021) (0)
- Glucose Catabolism with Resultant Formation of Reactive Oxygen Species and Local Hypoxia Modulates the Induction and Expansion of Hematopoietic Stem Cells (2010) (0)
- Metabolic Endocrine Regulators of Hematopoietic Stem Cell Formation and Function. (2009) (0)
- Abstract 5151: Yap reprograms glutamine metabolism and supports growth during liver development and tumorigenesis (2015) (0)
- Metabolic Regulation of Hepatic Growth (2020) (0)
- Single Cell RNA‐sequencing (scRNA‐seq) Reveals Reprogramming and Functional Compensation Preceding Cellular Recovery in Multiple Models of Acute Liver Injury (2019) (0)
- Global Gene Expression Signatures in CD34+ Hematopoietic Cells Following Exposure to 16,16-Dimethylprostaglandin E2. (2009) (0)
- A Balancing Act: Role of HNF4α and β ‐catenin in Hepatobiliary Development and Cholangiocarcinoma Pathogenesis (2016) (0)
- Serotonergic regulation of hematopoietic stem cell production in the AGM (2014) (0)
- A machine learning liver-on-a-chip system for safer drug formulation (2022) (0)
- Su1388: NATURAL LANGUAGE PROCESSING ENABLES HIGHLY ACCURATE EXTRACTION OF DETAILED HISTOPATHOLOGIC FEATURES OF NONALCOHOLIC STEATOHEPATITIS AND FIBROSIS FROM PATHOLOGY REPORTS (2022) (0)
- WNTing no RASt for HCC (2017) (0)
- Chapter 29 – Other infections involving the liver (2004) (0)
- Abstract 5148: NR5A2 is essential for pancreas development and affects pancreas carcinogenesis (2015) (0)
- 3017 – MECHANISMS OF FLOW-DRIVEN TRANSCRIPTIONAL CONTROL OF HEMATOPOIETIC STEM CELL DEVELOPMENT VIA YAP/TAZ REGULATION (2022) (0)
- Vitamin D3 Modulates Definitive Hematopoiesis by Two Distinct Mechanisms in the Developing Zebrafish Embryo (2012) (0)
- 762 Control of Microenvironmental Cues Enables the Differentiation of Pluripotent Stem Cell Derived Hepatocyte-Like Cells to an Adult Phenotype (2014) (0)
- Board Practice 3 (2012) (0)
- Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer. (2023) (0)
- Abstract 2657: The role of NR5A2 in pancreas development and oncogenesis. (2013) (0)
- Abstract 1953: The role of NR5a2 in pancreas development and carcinogenesis (2014) (0)
- 97: MATHEMATICAL MODELING PREDICTS BOTH RESOLUTION AND PERSISTENCE OF LIVER INJURY INDEPENDENT OF ABSOLUTE SERUM TRANSAMINASE LEVEL, ENABLES REAL-TIME ESTIMATION OF ACTIVE LIVER INJURY (2022) (0)
- Abstract 1574: The Hippo pathway regulates liver development and tumorigenesis in zebrafish. (2013) (0)
- Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer (2019) (0)
- Serotonin regulates HSC formation via glucocorticoid production from the hypothalamic-pituitary-interrenal axis (2015) (0)
- Table of contents (2016) (0)
- Human Umbilical Cord Blood Stem Cell Function Is Augmented by Exposure to Prostaglandin E2. (2009) (0)
- A high-throughput chemical genetic screen in zebrafish establishes that prostaglandin E2 is a potent regulator of hematopoietic stem cell formation (2007) (0)
- Estrogen enhances HSPC production during development and regeneration (2014) (0)
- Vitamin D regulates hematopoietic stem cell maintenance by two distinct mechanisms (2014) (0)
- YAP-deLIVERing the directions and the fuel. (2022) (0)
- Kinetic modeling of transaminase values distinguishes active liver inflammation from resolution independent of absolute enzyme levels (2022) (0)
- Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis (2023) (0)
- An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery (2018) (0)
- Hypoxic Stress-Induced Serotonergic Stimulation Controls Hematopoietic Stem Cell Production Via the Hypothalamic-Pituitary-Interrenal Axis and Glucocorticoid Signaling (2015) (0)
- Genome-wide association and functional follow-up reveals new loci for kidney function | NOVA. The University of Newcastle's Digital Repository (2012) (0)
- Merkel Cel l Carc inoma (2001) (0)
- Tu1252: AN ENHANCED TOOLKIT FOR THE ALGORITHMIC DETECTION OF PATIENTS WITH AUTOIMMUNE HEPATITIS IN A MULTI-HOSPITAL HEALTHCARE SYSTEM (2022) (0)
- transplantation Prostaglandin-modulated umbilical cord blood hematopoietic stem cell (2014) (0)
- Estrogens Act As a Dorsal-Ventral Limiting Factor To Pattern The Hematopoietic Stem Cell Niche (2013) (0)
- Cap CASP, not SCAP, to fight steatohepatitis. (2022) (0)
- WNTing no RASt for hepatocellular carcinoma (2017) (0)
This paper list is powered by the following services:
Other Resources About Wolfram Goessling
What Schools Are Affiliated With Wolfram Goessling?
Wolfram Goessling is affiliated with the following schools:
