Xing-Fang Li
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Engineering Computer Science
Xing-Fang Li's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Electrical Engineering University of California, Berkeley
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Why Is Xing-Fang Li Influential?
(Suggest an Edit or Addition)According to Wikipedia, Xing-Fang Li is a toxicologist whose research involves the discovery and identification of water contaminants through the development of new analytical technologies, as well as the engineering of solutions to ensure safe drinking water. Li is a professor at the Department of Laboratory Medicine and Pathology at the University of Alberta in Canada. She is a Canada Research Chair in Analytical and Environmental Toxicology, and was appointed as a Fellow of the Royal Society of Canada in 2021.
Xing-Fang Li's Published Works
Published Works
- Arsenic Binding to Proteins (2013) (538)
- Drinking Water Disinfection Byproducts (DBPs) and Human Health Effects: Multidisciplinary Challenges and Opportunities. (2017) (416)
- DNA-mediated homogeneous binding assays for nucleic acids and proteins. (2013) (329)
- A microRNA-initiated DNAzyme motor operating in living cells (2017) (317)
- Aptamer binding assays for proteins: the thrombin example--a review. (2014) (284)
- Selection and analytical applications of aptamers (2006) (244)
- Potential carcinogenic hazards of non-regulated disinfection by-products: haloquinones, halo-cyclopentene and cyclohexene derivatives, N-halamines, halonitriles, and heterocyclic amines. (2011) (194)
- Characterization of new nitrosamines in drinking water using liquid chromatography tandem mass spectrometry. (2006) (190)
- Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters. (2008) (174)
- Characterization and determination of chloro- and bromo-benzoquinones as new chlorination disinfection byproducts in drinking water. (2010) (167)
- Dynamic DNA Assemblies Mediated by Binding-Induced DNA Strand Displacement (2013) (159)
- Aptamers facilitating amplified detection of biomolecules. (2015) (151)
- Occurrence and formation of chloro- and bromo-benzoquinones during drinking water disinfection. (2012) (149)
- Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. (2004) (146)
- Binding-Induced DNA Nanomachines Triggered by Proteins and Nucleic Acids. (2015) (140)
- Selection of aptamers against live bacterial cells. (2008) (135)
- Detection of Viable but Nonculturable Escherichia coli O157:H7 Bacteria in Drinking Water and River Water (2008) (131)
- Detection of Escherichia coli O157:H7 using gold nanoparticle labeling and inductively coupled plasma mass spectrometry. (2010) (126)
- A toxic disinfection by-product, 2,6-dichloro-1,4-benzoquinone, identified in drinking water. (2010) (121)
- Ultrasensitive detection of proteins by amplification of affinity aptamers. (2006) (121)
- Aptamer-linked assay for thrombin using gold nanoparticle amplification and inductively coupled plasma-mass spectrometry detection. (2009) (120)
- Assembling DNA through affinity binding to achieve ultrasensitive protein detection. (2013) (113)
- Halobenzoquinones in swimming pool waters and their formation from personal care products. (2013) (110)
- Ultrasensitive assays for proteins. (2007) (109)
- Peer Reviewed: Arsenic Speciation (2004) (108)
- Interaction of trivalent arsenicals with metallothionein. (2003) (106)
- Aptamer-based affinity chromatographic assays for thrombin. (2008) (106)
- Thermal Stability of DNA Functionalized Gold Nanoparticles (2013) (105)
- Aptamer-modified monolithic capillary chromatography for protein separation and detection. (2008) (103)
- Selection and analytical applications of aptamers binding microbial pathogens (2011) (102)
- Analytical and toxicity characterization of halo-hydroxyl-benzoquinones as stable halobenzoquinone disinfection byproducts in treated water. (2014) (101)
- Interaction of oxaliplatin, cisplatin, and carboplatin with hemoglobin and the resulting release of a heme group. (2004) (99)
- Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing. (2016) (99)
- Binding of Dimethylarsinous Acid to Cys-13α of Rat Hemoglobin Is Responsible for the Retention of Arsenic in Rat Blood (2007) (95)
- Solid-phase extraction and high-performance liquid chromatography mass spectrometry analysis of nitrosamines in treated drinking water and wastewater (2011) (94)
- Chemical and toxicological characterization of halobenzoquinones, an emerging class of disinfection byproducts. (2015) (93)
- Use of quantum dots in the development of assays for cancer biomarkers (2010) (91)
- A cell-microelectronic sensing technique for profiling cytotoxicity of chemicals. (2008) (90)
- A molecular translator that acts by binding-induced DNA strand displacement for a homogeneous protein assay. (2012) (89)
- DNA aptamers binding to multiple prevalent M-types of Streptococcus pyogenes. (2011) (87)
- Cytotoxicity and oxidative damage induced by halobenzoquinones to T24 bladder cancer cells. (2013) (85)
- Emerging Disinfection Byproducts, Halobenzoquinones: Effects of Isomeric Structure and Halogen Substitution on Cytotoxicity, Formation of Reactive Oxygen Species, and Genotoxicity. (2016) (81)
- Tunable aptamer capillary electrophoresis and its application to protein analysis. (2008) (81)
- Arsenic on the Hands of Children after Playing in Playgrounds (2004) (75)
- Reverse transcription-multiplex PCR assay for simultaneous detection of Escherichia coli O157:H7, Vibrio cholerae O1, and Salmonella Typhi. (2004) (69)
- Hydrophilic interaction liquid chromatography-tandem mass spectrometry determination of estrogen conjugates in human urine. (2008) (66)
- Formation of N-nitrosodiphenylamine and two new N-containing disinfection byproducts from chloramination of water containing diphenylamine. (2009) (65)
- Applications of aptamer affinity chromatography (2012) (64)
- Binding-induced DNA assembly and its application to yoctomole detection of proteins. (2012) (62)
- Column-switching reversed phase-hydrophilic interaction liquid chromatography/tandem mass spectrometry method for determination of free estrogens and their conjugates in river water. (2008) (59)
- Aptamer capturing of enzymes on magnetic beads to enhance assay specificity and sensitivity. (2011) (58)
- Therapeutic and analytical applications of arsenic binding to proteins. (2015) (54)
- Production of Shiga-like toxins in viable but nonculturable Escherichia coli O157:H7. (2010) (54)
- Halobenzoquinone-Induced Developmental Toxicity, Oxidative Stress, and Apoptosis in Zebrafish Embryos. (2018) (52)
- UV-induced transformation of four halobenzoquinones in drinking water. (2013) (52)
- Induction of Escherichia coli O157:H7 into the viable but non-culturable state by chloraminated water and river water, and subsequent resuscitation. (2009) (50)
- Determination of 14 nitrosamines at nanogram per liter levels in drinking water. (2015) (49)
- Liquid chromatography-electrospray mass spectrometric studies of ginkgolides and bilobalide using simultaneous monitoring of proton, ammonium and sodium adducts. (2002) (49)
- Analytical characterization, occurrence, transformation, and removal of the emerging disinfection byproducts halobenzoquinones in water (2016) (48)
- Ultra pressure liquid chromatography-negative electrospray ionization mass spectrometry determination of twelve halobenzoquinones at ng/L levels in drinking water. (2013) (47)
- Kinetics of Proximity-Induced Intramolecular DNA Strand Displacement. (2016) (46)
- Liquid chromatography tandem mass spectrometry determination of free and conjugated estrogens in breast cancer patients before and after exemestane treatment. (2014) (46)
- Arsenic Species in Chicken Breast: Temporal Variations of Metabolites, Elimination Kinetics, and Residual Concentrations (2016) (45)
- Differentiation and detection of PDGF isomers and their receptors by tunable aptamer capillary electrophoresis. (2009) (45)
- Nontargeted identification of peptides and disinfection byproducts in water. (2016) (45)
- Simultaneous speciation of selenium and arsenic using elevated temperature liquid chromatography separation with inductively coupled plasma mass spectrometry detection (1998) (41)
- Direct large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry determination of artificial sweeteners sucralose and acesulfame in well water. (2014) (40)
- On‐line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline by Cunninghamella elegans (1998) (40)
- Removal of halo-benzoquinone (emerging disinfection by-product) precursor material from three surface waters using coagulation. (2013) (40)
- Liquid chromatography combined with atomic and molecular mass spectrometry for speciation of arsenic in chicken liver. (2014) (39)
- Mass Spectrometry Identification of N-Chlorinated Dipeptides in Drinking Water. (2017) (39)
- Polymeric micelles for GSH-triggered delivery of arsenic species to cancer cells. (2014) (39)
- Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. (2007) (37)
- Methylated Phenylarsenical Metabolites Discovered in Chicken Liver (2017) (36)
- Formation and Occurrence of Iodinated Tyrosyl Dipeptides in Disinfected Drinking Water. (2018) (36)
- Quantification of viable but nonculturable Escherichia coli O157:H7 by targeting the rpoS mRNA. (2010) (35)
- DNase-mediated single-cycle selection of aptamers for proteins blotted on a membrane. (2012) (35)
- Cell-electronic sensing of particle-induced cellular responses. (2008) (35)
- Electrospray ionization mass spectrometry characterization of interactions of newly identified water disinfection byproducts halobenzoquinones with oligodeoxynucleotides. (2010) (33)
- Convenient method for the determination of trace amounts of germanium by hydride generation direct current plasma atomic emission spectrometry: interference reduction by L-cystine and L-cysteine (1989) (33)
- Characterization of intact hemoglobin and oxaliplatin interaction by nanoelectrospray ionization tandem mass spectrometry. (2005) (33)
- Characterization of natural organic matter in water for optimizing water treatment and minimizing disinfection by-product formation. (2016) (33)
- "One-pot" methylation in glycomics application: esterification of sialic acids and permanent charge construction. (2007) (33)
- Biomonitoring of urinary tamoxifen and its metabolites from breast cancer patients using nonaqueous capillary electrophoresis with electrospray mass spectrometry (2001) (33)
- Real-time cell-microelectronic sensing of nanoparticle-induced cytotoxic effects. (2013) (32)
- Ascorbic Acid Assisted High Performance Liquid Chromatography Mass Spectrometry Differentiation of Isomeric C-Chloro- and N-Chloro-Tyrosyl Peptides in Water. (2017) (31)
- p-Azidophenylarsenoxide: An Arsenical "Bait" for the In Situ Capture and Identification of Cellular Arsenic-Binding Proteins. (2016) (30)
- An improved SELEX technique for selection of DNA aptamers binding to M-type 11 of Streptococcus pyogenes. (2016) (29)
- Intact human holo-transferrin interaction with oxaliplatin. (2005) (29)
- Glutathione-mediated detoxification of halobenzoquinone drinking water disinfection byproducts in T24 cells. (2014) (29)
- Formation of water disinfection byproduct 2,6-dichloro-1,4-benzoquinone from chlorination of green algae. (2017) (28)
- Studies of cisplatin and hemoglobin interactions using nanospray mass spectrometry and liquid chromatography with inductively-coupled plasma mass spectrometry. (2003) (28)
- Identification of tobacco-specific nitrosamines as disinfection byproducts in chloraminated water. (2014) (28)
- Binding of dimethylarsinous acid to cys-13alpha of rat hemoglobin is responsible for the retention of arsenic in rat blood. (2007) (27)
- Mass spectrometric studies of cisplatin-induced changes of hemoglobin. (2003) (27)
- Sweetened Swimming Pools and Hot Tubs (2017) (27)
- Effects of halobenzoquinone and haloacetic acid water disinfection byproducts on human neural stem cells. (2017) (26)
- Identification of reactive cysteines in a protein using arsenic labeling and collision-induced dissociation tandem mass spectrometry. (2008) (26)
- Precursors of Halobenzoquinones and Their Removal During Drinking Water Treatment Processes. (2015) (26)
- Degradation of phenanthrene and pyrene by microorganisms isolated from marine sediment and seawater (1994) (26)
- Competitive protection of aptamer-functionalized gold nanoparticles by controlling the DNA assembly. (2011) (25)
- Determination of testosterone and its metabolites using liquid chromatography with elevated column temperature and flow-rate gradient (2002) (25)
- Bacterial Transformation of Pyrene in a Marine Environment (1996) (25)
- "One-pot" fabrication of clickable monoliths for enzyme reactors. (2013) (25)
- Reliability of using urinary and blood trichloroacetic acid as a biomarker of exposure to chlorinated drinking water disinfection byproducts (2009) (24)
- Pesticides and trace elements in cannabis: Analytical and environmental challenges and opportunities. (2019) (24)
- Detection of fortification of ginkgo products using nanoelectrospray ionization mass spectrometry. (2005) (23)
- Microbial degradation of pyrene and characterization of a metabolite (1996) (23)
- Validation of urinary trichloroacetic acid as a biomarker of exposure to drinking water disinfection by-products. (2009) (22)
- Formation, Identification, and Occurrence of New Bromo- and Mixed Halo-Tyrosyl Dipeptides in Chloraminated Water. (2019) (22)
- Spatial and temporal occurrence of N-nitrosamines in seven drinking water supply systems (2013) (22)
- Chromium on the Hands of Children After Playing in Playgrounds Built from Chromated Copper Arsenate (CCA)–Treated Wood (2005) (21)
- Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry. (2009) (20)
- Silica Monolith Nested in Sponge (SiMNS): A Composite Monolith as a New Solid Phase Extraction Material for Environmental Analysis. (2019) (20)
- Mesoporous materials in peptidome analysis. (2012) (20)
- Direct evidence for co-binding of cisplatin and cadmium to a native zinc- and cadmium-containing metallothionein (2003) (20)
- Analysis of nitrosamines by capillary electrospray‐high‐field asymmetric waveform ion mobility spectrometry‐MS with programmed compensation voltage (2007) (20)
- Mass spectrometry study of hemoglobin-oxaliplatin complexes in colorectal cancer patients and potential association with chemotherapeutic responses. (2006) (19)
- Halobenzoquinone-Induced Alteration of Gene Expression Associated with Oxidative Stress Signaling Pathways. (2018) (18)
- New methods for identification of disinfection byproducts of toxicological relevance: Progress and future directions. (2021) (18)
- Nontargeted identification and predicted toxicity of new byproducts generated from UV treatment of water containing micropollutant 2-mercaptobenzothiazole. (2020) (18)
- Wastewater-Based Epidemiology for Community Monitoring of SARS-CoV-2: Progress and Challenges (2021) (18)
- Cytotoxicity and genotoxicity of phenazine in two human cell lines. (2014) (17)
- Determination of microcystins in water using integrated solid-phase microextraction with microbore high-performance liquid chromatography-electrospray quadruple time-of-flight mass spectrometry. (2006) (17)
- Top-down characterization of proteins and drug-protein complexes using nanoelectrospray tandem mass spectrometry. (2006) (17)
- Electrospray ionization tandem mass spectrometry analysis of the reactivity of structurally related bromo-methyl-benzoquinones toward oligonucleotides. (2011) (16)
- A Genome Editing Nanomachine Constructed with a Clustered Regularly Interspaced Short Palindromic Repeats System and Activated by Near-Infrared Illumination. (2020) (16)
- The Effects of SELEX Conditions on the Resultant Aptamer Pools in the Selection of Aptamers Binding to Bacterial Cells (2015) (16)
- Amplified binding-induced homogeneous assay through catalytic cycling of analyte for ultrasensitive protein detection. (2016) (15)
- Terpolymer Micelles for the Delivery of Arsenic to Breast Cancer Cells: The Effect of Chain Sequence on Polymeric Micellar Characteristics and Cancer Cell Uptake. (2016) (15)
- Stable Isotopic Labeling and Nontarget Identification of ng/L Amino Contaminants in Water. (2019) (15)
- Electronic deoxyribonucleic acid (DNA) microarray detection of viable pathogenic Escherichia coli, Vibrio cholerae, and Salmonella typhi. (2006) (15)
- Characterization of Mechanisms of Glutathione Conjugation with Halobenzoquinones in Solution and HepG2 Cells. (2018) (15)
- Investigation of interaction between human hemoglobin A0 and platinum anticancer drugs by capillary isoelectric focusing with whole column imaging detection. (2008) (15)
- Cytotoxicity of Halogenated Tyrosyl Compounds, an Emerging Class of Disinfection By-Products. (2020) (14)
- Capillary electrophoretic separation of polynuclear aromatic hydrocarbons using sodium cholate in mixed aqueous–organic buffers (1998) (14)
- Yoctomole detection of proteins using solid phase binding-induced DNA assembly. (2013) (14)
- Identification and characterization of cysteinyl exposure in proteins by selective mercury labeling and nano-electrospray ionization quadrupole time-of-flight mass spectrometry. (2010) (13)
- Recent applications and critical evaluation of using artificial sweeteners to assess wastewater impact (2019) (13)
- Aptamer binding assay for the E antigen of Hepatitis B using modified aptamers with G-quadruplex structures. (2020) (12)
- Studying developmental neurotoxic effects of bisphenol A (BPA) using embryonic stem cells. (2015) (12)
- Cyanobacterial bloom dynamics in Lake Taihu. (2015) (12)
- Targeted Enlargement of Aptamer Functionalized Gold Nanoparticles for Quantitative Protein Analysis (2016) (11)
- Identification of precursors and mechanisms of tobacco-specific nitrosamine formation in water during chloramination. (2015) (11)
- Analytical characterization of N-halogenated peptides produced by disinfection: Formation, degradation, and occurrence in water (2019) (11)
- An electronic DNA microarray technique for detection and differentiation of viable Campylobacter species. (2006) (10)
- Quantitative synthesis of protein-DNA conjugates with 1 : 1 stoichiometry. (2018) (10)
- A real-time cell-electronic sensing method for comparative analysis of toxicity of water contaminants (2014) (10)
- Enzymatic digestion and chromatographic analysis of arsenic species released from proteins. (2009) (10)
- Multidrug Resistance Protein 4 (MRP4/ABCC4) Protects Cells from the Toxic Effects of Halobenzoquinones. (2017) (10)
- An efficient method to enhance recovery and detection of SARS-CoV-2 RNA in wastewater (2022) (8)
- In situ extraction/preconcentration of PCBs and PAHs from aqueous samples using polytetrafluoroethylene tubing. (2002) (7)
- A hidden risk: Survival and resuscitation of Escherichia coli O157:H7 in the viable but nonculturable state after boiling or microwaving. (2020) (7)
- Wastewater Based Surveillance of SARS-CoV-2: Challenges and Perspective from a Canadian Inter-laboratory Study (2022) (7)
- Determination of eighty-two pesticides and application to screening pesticides in cannabis growing facilities. (2021) (7)
- Arsenic on the Hands of Children: Wang et al. Respond (2005) (7)
- Assembling DNA Through Affinity Binding to Achieve Ultrasensitive Protein Detection (2013) (7)
- Nontargeted Identification of an N-Heterocyclic Compound in Source Water and Wastewater as a Precursor of Multiple Nitrosamines. (2020) (6)
- Formation Mechanism of Iodinated Aromatic Disinfection Byproducts: Acid Catalysis with H2OI. (2022) (5)
- Visualization of fingerprints made easy with dye solution on cellulose membrane (2018) (5)
- Analytical Methods for Predicted DBPs of Probable Toxicological Significance (2011) (5)
- Keep swimming but stop peeing in the pools. (2017) (5)
- Disinfection: A Trade-Off Between Microbial and Chemical Risks (2019) (4)
- Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene. (2004) (4)
- Real-Time Cell-Electronic Sensing of Coal Fly Ash Particulate Matter for Toxicity-Based Air Quality Monitoring. (2016) (4)
- Advances in mass spectrometry-based omics analysis of trace organics in water (2020) (4)
- N-Nitrosamine formation from chloramination of two common ionic liquids. (2020) (4)
- Rapid and efficient polymerase chain reaction-based strategies for one-site and two-site mutagenesis. (2004) (3)
- Occurrence of nitrosamines and their precursors in North American drinking waters (2020) (3)
- Integration of solid phase extraction with HILIC-MS/MS for analysis of free amino acids in source water. (2022) (3)
- On-Site Viral Inactivation and RNA Preservation of Gargle and Saliva Samples Combined with Direct Analysis of SARS-CoV-2 RNA on Magnetic Beads (2022) (3)
- Detection of Viable But Non-culturable Escherichia coli O 157 : H 7 in 1 Drinking Water and River Water 2 (2008) (2)
- Protein sequencing using microreactors and capillary electrophoresis with thermo-optical absorbance detection (1997) (2)
- Evaluation of approaches for consumers to eliminate chlorine off-flavors from drinking water at point-of-use (2015) (2)
- Cell‐Electronic Sensing of Cellular Responses to Micro‐ and Nanoparticles for Environmental Applications (2014) (2)
- Nitrosamine Occurrence Survey [ Project # 4461 ] (2016) (2)
- Occurrence of N-nitrosodiphenylamine and N-nitrosodimethylamine in 38 Drinking Water Distribution Systems in Canada and the U.S.A. (2010) (1)
- Direct analysis of nine pharmaceuticals in culture media by use of cartridge separation with electrospray mass spectrometric detection (2002) (1)
- High Sensitivity Analysis of PTH Amino Acids (1995) (1)
- Maternal and child biomonitoring strategies and levels of exposure in western Canada during the past seventeen years: The Alberta Biomonitoring Program: 2005-2021. (2022) (1)
- Emerging Disinfection Byproduct 2,6-Dichlorobenzoquinone-Induced Cardiovascular Developmental Toxicity of Embryonic Zebrafish and Larvae: Imaging and Transcriptome Analysis (2022) (1)
- Titelbild: Methylated Phenylarsenical Metabolites Discovered in Chicken Liver (Angew. Chem. 24/2017) (2017) (1)
- Closing the Gap of Known and Unknown Halogenated Nitrogenous Disinfection Byproducts in Water: Advanced Mass Spectrometry Techniques (2022) (1)
- Unique On-Site Spinning Sampling of Highly Water-Soluble Organics Using Functionalized Monolithic Sorbents (2022) (1)
- Electronic cigarettes and toxic substances, including arsenic species. (2020) (1)
- Analysis of N-nitrosamines Formed in Various Source Waters Treated with Eleven Disinfection Processes (2008) (1)
- Analytical discovery of water disinfection byproducts of toxicological relevance: highlighting halobenzoquinones (2021) (0)
- Cytotoxicityof Halogenated Tyrosyl Compounds, anEmerging Class of Disinfection Byproducts (2020) (0)
- Arsenic on Children’s Hands: Le et al. Respond (2005) (0)
- Arsenic on the hands of children (multiple letters) [1] (2005) (0)
- From Detection to Remediation: Analytical Science at the Forefront of Environmental Research. (2022) (0)
- Electronic Microarray Technique for Detection of Nine Base Substitutions including Single-nucleotide Poly- Morphisms in the Human Ogg1 Gene, Zhilong Gong, 1# (2004) (0)
- News: Dr. Xing-Fang Li is awarded Canada Research Chair in Analytical Chemistry and Environmental Toxicology (2019) (0)
- From Detection to Remediation: Analytical Science at the Forefront of Environmental Research (2022) (0)
- News: Dr. Xing-Fang Li receives Environment Research and Development Award from the Chemical Institute of Canada (2017) (0)
- Aspartame-Sweetened Tap Water: Transformation Products and 2,6-Dichloro-1,4-Benzoquinone Formation (2023) (0)
- Glycoanalysis of Bacterial Glycome (2010) (0)
- Arsenic-protein binding: A quantitative overview (2012) (0)
- Glyphosate Results Revisited (2004) (0)
- From Detection to Remediation: Analytical Science at the Forefront of Environmental Research. (2022) (0)
- Multiplex Assays Enable Simultaneous Detection and Identification of SARS-CoV-2 Variants of Concern in Clinical and Wastewater Samples (2023) (0)
- Cover Picture: Methylated Phenylarsenical Metabolites Discovered in Chicken Liver (Angew. Chem. Int. Ed. 24/2017) (2017) (0)
- The Effects of SELEX Conditions on the Resultant Aptamer Pools in the Selection of Aptamers Binding to Bacterial Cells (2015) (0)
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