Yogesh Chandra Awasthi
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Molecular Biology
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Biochemistry
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Biology
Yogesh Chandra Awasthi's Degrees
- Bachelors Biochemistry Delhi University
- Masters Biochemistry Delhi University
- PhD Biochemistry Delhi University
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(Suggest an Edit or Addition)Yogesh Chandra Awasthi's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nomenclature for human glutathione transferases. (1992) (633)
- Naturally occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties. (1994) (475)
- Purification and properties of human erythrocyte glutathione peroxidase. (1975) (317)
- Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. (2004) (292)
- Role of Glutathione S-Transferases in Protection against Lipid Peroxidation (2001) (288)
- Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. (1998) (263)
- Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling. (2003) (252)
- Human glutathione S-transferases. (1994) (201)
- Interrelationship between anionic and cationic forms of glutathione S-transferases of human liver. (1980) (194)
- Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases. (2004) (193)
- Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons. (1997) (184)
- Accelerated Metabolism and Exclusion of 4-Hydroxynonenal through Induction of RLIP76 and hGST5.8 Is an Early Adaptive Response of Cells to Heat and Oxidative Stress* (2001) (181)
- Role of 4-hydroxynonenal in stress-mediated apoptosis signaling. (2003) (173)
- Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases. (2005) (172)
- Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse. (2004) (153)
- Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses. (1996) (151)
- Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin. (2000) (151)
- Curcumin-glutathione interactions and the role of human glutathione S-transferase P1-1. (2000) (132)
- Mitogenic Responses of Vascular Smooth Muscle Cells to Lipid Peroxidation-derived Aldehyde 4-Hydroxy-trans-2-nonenal (HNE) (2006) (128)
- The role of human glutathione S-transferases hGSTA1-1 and hGSTA2-2 in protection against oxidative stress. (1999) (128)
- Enzymatic conjugation of erythrocyte glutathione with 1-chloro-2,4- dinitrobenzene: the fate of glutathione conjugate in erythrocytes and the effect of glutathione depletion on hemoglobin (1981) (123)
- Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling. (2001) (123)
- Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa. (1999) (122)
- Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells. (1999) (119)
- Glutathione S-transferases of human lung: characterization and evaluation of the protective role of the alpha-class isozymes against lipid peroxidation. (1992) (114)
- Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): A novel link between G‐protein and tyrosine kinase signaling and drug resistance (2003) (113)
- Useful agents for the study of glutathione metabolism in erythroyctes. Organic hydroperoxides. (1974) (108)
- Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7). (1994) (107)
- Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1). (2007) (107)
- Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death. (2008) (103)
- Introduction of purified hexosaminidase A into Tay-Sachs leukocytes by means of immunoglobulin-coated liposomes. (1976) (102)
- Primary and secondary structural analyses of glutathione S-transferase π from human placenta (1990) (101)
- Hepatic xenobiotic metabolizing enzymes in two species of benthic fish showing different prevalences of contaminant-associated liver neoplasms. (1992) (100)
- Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. (1994) (97)
- Regression of melanoma in a murine model by RLIP76 depletion. (2006) (97)
- Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling. (2010) (91)
- Cells Preconditioned with Mild, Transient UVA Irradiation Acquire Resistance to Oxidative Stress and UVA-induced Apoptosis (2003) (90)
- Role of 4-hydroxynonenal and its metabolites in signaling (2007) (89)
- Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene. (1997) (89)
- 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells. (2008) (88)
- Induction of glutathione S‐transferase π as a bioassay for the evaluation of potency of inhibitors of benzo(a)pyrene‐induced cancer in a murine model (1997) (83)
- Active Site Architecture of Polymorphic Forms of Human GlutathioneS-Transferase P1-1 Accounts for Their Enantioselectivity and Disparate Activity in the Glutathione Conjugation of 7β,8α-Dihydroxy-9α, 10α-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene (1997) (83)
- RLIP76 is a major determinant of radiation sensitivity. (2005) (83)
- Dietary curcumin prevents ocular toxicity of naphthalene in rats. (2000) (82)
- Dinitrophenyl glutathione efflux from human erythrocytes is primary active ATP-dependent transport. (1986) (81)
- RLIP76, a non-ABC transporter, and drug resistance in epilepsy (2005) (80)
- Glutathione S-transferases in human and rodent skin: multiple forms and species-specific expression. (1991) (79)
- Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. (2008) (79)
- Studies on Human β-d-N-Acetylhexosaminidases I. PURIFICATION AND PROPERTIES (1974) (79)
- Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene. (1998) (79)
- RLIP76 and Cancer (2008) (78)
- Role of α Class Glutathione S-Transferases as Antioxidant Enzymes in Rodent Tissues (2002) (77)
- RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer. (2005) (77)
- RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics. (2002) (76)
- Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis. (2004) (75)
- Human glutathione S-transferases. Characterization of the anionic forms from lung and placenta. (1984) (73)
- Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450 isoforms in hepatitis of mice infected with Helicobacter hepaticus. (1997) (73)
- Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil. (2000) (72)
- Purification and characterization of glutathione S-transferases of human kidney. (1987) (71)
- Induction of glutathione S-transferase hGST 5.8 is an early response to oxidative stress in RPE cells. (1999) (71)
- Differential expression of α, μ and π classes of isozymes of glutathione S-transferase in bovine lens, cornea, and retina (1988) (71)
- Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin. (2005) (69)
- Glutathione and glutathione S-transferases in a human plasma cell line resistant to melphalan. (1989) (67)
- Effect of chronic cadmium exposure on glutathione S-transferase and glutathione peroxidase activities in rhesus monkey: the role of selenium. (1993) (65)
- Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences. (2001) (65)
- RLIP76: a target for kidney cancer therapy. (2009) (65)
- Glutathione S-transferases of human brain. Evidence for two immunologically distinct types of 26500-Mr subunits. (1985) (65)
- Studies of human kidney gamma-glutamyl transpeptidase. Purification and structural, kinetic and immunological properties. (1976) (64)
- Membrane Association of Glutathione S-Transferase mGSTA4-4, an Enzyme That Metabolizes Lipid Peroxidation Products* (2002) (63)
- Role of glycosylation in protein disulfide formation and cataractogenesis. (1980) (63)
- 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. (2008) (62)
- Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. (2004) (62)
- Protection of HLE B-3 cells against hydrogen peroxide- and naphthalene-induced lipid peroxidation and apoptosis by transfection with hGSTA1 and hGSTA2. (2002) (61)
- RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes. (2001) (60)
- Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity. (2003) (59)
- Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues. (2001) (59)
- Detoxification of xenobiotics by glutathione S‐transferases in erythrocytes: the transport of the conjugate of glutathione and 1‐chloro‐2,4‐dinitrobenzene (1983) (59)
- ATP‐dependent transport systems for organic anions (1993) (58)
- Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76. (2003) (58)
- Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface. (1999) (56)
- Purification and properties of glutathione peroxidase from human placenta. (1979) (56)
- Purification and characterization of dinitrophenylglutathione ATPase of human erythrocytes and its expression in other tissues. (1990) (54)
- Association of glutathione S-transferase isozyme-specific induction and lipid peroxidation in two inbred strains of mice subjected to chronic dietary iron overload. (1998) (54)
- Glutathione-Conjugate Transport by RLIP76 Is Required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis (2011) (54)
- Role of RLIP76 in doxorubicin resistance in lung cancer. (2009) (52)
- Differential inhibition of rat and human glutathione S-transferase isoenzymes by plant phenols. (1986) (52)
- Purification and characterization of a new form of glutathione S-transferase from human erythrocytes. (1984) (52)
- Different forms of human liver glutathione S-transferases arise from dimeric combinations of at least four immunologically and functionally distinct subunits. (1985) (51)
- A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues. (1994) (50)
- Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal. (2006) (50)
- Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis. (2006) (50)
- POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis. (2005) (49)
- Identification of membrane-anchoring domains of RLIP76 using deletion mutant analyses. (2004) (49)
- RLIP76 in defense of radiation poisoning. (2008) (49)
- Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells. (2008) (49)
- Studies on Human β-d-N-Acetylhexosaminidases II. KINETIC AND STRUCTURAL PROPERTIES (1974) (49)
- Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells. (2003) (48)
- ATP-Dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activity. (1998) (48)
- The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance. (2007) (48)
- Gender-related differences in susceptibility of A/J mouse to benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis. (1998) (48)
- Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu. (1999) (48)
- An Alpha Class Mouse Glutathione S-Transferase with Exceptional Catalytic Efficiency in the Conjugation of Glutathione with 7β,8α-Dihydroxy-9α,10α-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene* (1996) (47)
- Glutathione S-transferases of mouse liver: sex-related differences in the expression of various isozymes. (1992) (47)
- The effect of curcumin on glutathione-linked enzymes in K562 human leukemia cells. (1999) (47)
- Purification and properties of sphingolipid beta-galactosidases from human placenta. (1979) (47)
- Irreversible inhibition of hepatic glutathione S-transferase by ciprofibrate, a peroxisome proliferator. (1984) (47)
- A subgroup of class α glutathione S‐transferases Cloning of cDNA for mouse lung glutathione S‐transferase GST 5.7 (1992) (46)
- The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice. (2006) (46)
- 4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway* (2013) (46)
- Glutathione S-transferases of human skin: qualitative and quantitative differences in men and women. (1993) (46)
- RLIP76 (RALBP1)‐mediated transport of leukotriene C4 (LTC4) in cancer cells: Implications in drug resistance (2004) (44)
- ATP-Dependent human erythrocyte glutathione-conjugate transporter. I. Purification, photoaffinity labeling, and kinetic characteristics of ATPase activity. (1998) (44)
- Endothelial glutathione-S-transferase A4-4 protects against oxidative stress and modulates iNOS expression through NF-kappaB translocation. (2008) (44)
- Iron-induced lipid peroxidation in rat liver is accompanied by preferential induction of glutathione S-transferase 8-8 isozyme. (1995) (43)
- Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus. (1997) (42)
- Gender related differences in the expression and characteristics of glutathione S-transferases of human colon. (1992) (42)
- Glutathione S-transferase 8-8 is localized in smooth muscle cells of rat aorta and is induced in an experimental model of atherosclerosis. (1995) (42)
- A novel dinitrophenylglutathione‐stimulated ATPase is present in human erythrocyte membranes (1988) (42)
- Age- and Gender-Related Trends in the Expression of Glutathione S-Transferases in Human Nasal Mucosa (1995) (42)
- Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal. (1995) (41)
- Purification and properties of human kidney-cortex hexosaminidases A and B. (1977) (41)
- Purification and characterization of an ATPase from human liver which catalyzes ATP hydrolysis in the presence of the conjugates of bilirubin bile acids and glutathione. (1991) (41)
- Toxicology of Glutathione Transferases (2006) (41)
- Transfection of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme, mouse GSTA4-4, confers doxorubicin resistance to Chinese hamster ovary cells. (1996) (41)
- Determinants of differential doxorubicin sensitivity between SCLC and NSCLC (2006) (41)
- Glutathione S-transferases and glutathione peroxidases in doxorubicin-resistant murine leukemic P388 cells. (1989) (40)
- Enhanced expression of glutathione-S-transferase A1-1 protects against oxidative stress in human retinal pigment epithelial cells. (2005) (40)
- Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer. (2007) (39)
- Energy dependent transport of xenobiotics and its relevance to multidrug resistance. (2003) (39)
- Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes. (1986) (39)
- Modulation of cisplatin cytotoxicity by sulphasalazine. (1994) (39)
- Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity. (2017) (38)
- A group of novel glutathione S-transferase isozymes showing high activity towards 4-hydroxy-2-nonenal are present in bovine ocular tissues. (1994) (37)
- Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent. (2010) (37)
- Glutathione S-transferases of the bovine retina. Evidence that glutathione peroxidase activity is the result of glutathione S-transferase. (1982) (37)
- Organic anion-transporting ATPase of rat liver. I. Purification, photoaffinity labeling, and regulation by phosphorylation. (1994) (36)
- Toxicity of oxidized β-carotene to cultured human cells (2005) (35)
- Interrelationship of hexosaminidases A and B: conformation of the common and the unique subunit theory. (1976) (35)
- Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells. (2011) (35)
- The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S‐(dinitrophenyl)glutathione ATPase of human erythrocyte (1991) (34)
- Role of alpha class glutathione S-transferases as antioxidant enzymes in rodent tissues. (2002) (34)
- Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene. (1997) (33)
- Enzymatic conjugation of erythrocyte glutathione with 1-chloro-2,4-dinitrobenzene: the fate of glutathione conjugate in erythrocytes and the effect of glutathione depletion on hemoglobin. (1981) (32)
- Dinitrophenyl S-glutathione ATPase purified from human muscle catalyzes ATP hydrolysis in the presence of leukotrienes. (1992) (32)
- The role of PKCα and RLIP76 in transport‐mediated doxorubicin‐resistance in lung cancer (2005) (32)
- The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4. (2012) (31)
- Organic anion-transporting ATPase of rat liver. II. Functional reconstitution of active transport and regulation by phosphorylation. (1994) (31)
- Purification and characterization of glutathione S-transferases in human retina. (1984) (31)
- Human liver glutathione S-transferase psi. Chemical characterization and secondary-structure comparison with other mammalian glutathione S-transferases. (1987) (31)
- A Central Role of RLIP76 in Regulation of Glycemic Control (2009) (31)
- Interactions of melphalan with glutathione and the role of glutathione S-transferase. (1996) (30)
- Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes. (1998) (30)
- Activity of mouse liver glutathione S-transferases toward trans,trans-muconaldehyde and trans-4-hydroxy-2-nonenal. (1993) (29)
- Interaction of annexins IV and VI with ATP (1997) (29)
- Modulation of doxorubicin cytotoxicity by ethacrynic acid (1996) (29)
- Evidence for the involvement of histidine at the active site of glutathione S-transferase psi from human liver. (1987) (28)
- Purification and characterization of unique glutathione S-transferases from human muscle. (1988) (28)
- Gsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity. (2013) (28)
- Human erythrocyte glutathione S-transferase: a possible marker of chemical exposure. (1987) (28)
- ATP-Dependent colchicine transport by human erythrocyte glutathione conjugate transporter. (1999) (28)
- Characterization of a novel α-class anionic glutathione S-transferase isozyme from human liver (1990) (28)
- Functional reconstitution of Ral-binding GTPase activating protein, RLIP76, in proteoliposomes catalyzing ATP-dependent transport of glutathione conjugate of 4-hydroxynonenal. (2002) (27)
- Purification and properties of bovine lens glutathione S-transferase. (1980) (27)
- Physiological and Pharmacological Significance of Glutathione-Conjugate Transport (2009) (27)
- Rlip depletion prevents spontaneous neoplasia in TP53 null mice (2018) (27)
- Characterization of a novel glutathione S-transferase isoenzyme from mouse lung and liver having structural similarity to rat glutathione S-transferase 8-8. (1991) (26)
- Subunit structure of human and rat glutathione S-transferases. (1985) (26)
- Role of SMC1 in Overcoming Drug Resistance in Triple Negative Breast Cancer (2013) (25)
- Immunohistochemical localization, purification, and characterization of human urinary bladder glutathione S-transferases. (1991) (25)
- Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells. (1996) (25)
- Purification and characterization of glutathione S-transferase from sugarcane leaves (1991) (24)
- Glutathione S-transferases of mouse lung. Selective binding of benzo[a]pyrene metabolites by the subunits which are preferentially induced by t-butylated hydroxyanisole. (1987) (24)
- Loss of glutathione S‐transferase A4 accelerates obstruction‐induced tubule damage and renal fibrosis (2012) (24)
- Effect of butylated hydroxytoluene on glutathione S-transferase and glutathione peroxidase activities in rat liver. (1983) (24)
- Role of Glutathione S-Transferases in Protection against Lipid Peroxidation OVEREXPRESSION OF hGSTA2-2 IN K562 CELLS PROTECTS AGAINST HYDROGEN PEROXIDE-INDUCED APOPTOSIS AND INHIBITS JNK AND CASPASE 3 ACTIVATION* (2001) (24)
- Selective expression of the three classes of glutathione S-transferase isoenzymes in mouse tissues. (1990) (24)
- Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression. (2005) (24)
- Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76). (2002) (24)
- Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions. (2007) (23)
- Transport of glutathione-conjugates in human erythrocytes. (2000) (23)
- Glutathione S-transferase isoenzymes in human lung tumors. (1988) (23)
- Stimulation of a human erythrocyte membrane ATPase by glutathione conjugates. (1990) (23)
- Primary and secondary structural analyses of glutathione S-transferase pi from human placenta. (1990) (23)
- Independent segregation of glutathione S-transferase and fatty acid ethyl ester synthase from pancreas and other human tissues. (1991) (22)
- Interrelationship between cationic and anionic forms of glutathione S-transferases of bovine ocular lens. (1980) (22)
- Mercapturic acid pathway enzymes in bovine ocular lens, cornea, retina and retinal pigmented epithelium. (1982) (22)
- A specific, sensitive, and rapid method for the determination of glutathione and its application in ocular tissues. (1992) (22)
- Differential carcinogenicity of benzo[a]pyrene in male and female CD-1 mouse lung. (1997) (22)
- Characterization of glutathione S-transferases of human cornea. (1985) (22)
- Attenuation of 4-hydroxynonenal-induced cataractogenesis in rat lens by butylated hydroxytoluene. (1996) (22)
- Amino acid residue 104 in an alpha-class glutathione S-transferase is essential for the high selectivity and specificity of the enzyme for 4-hydroxynonenal. (1996) (21)
- Rat lung glutathione S-transferases. Evidence for two distinct types of 22000-Mr subunits. (1984) (21)
- Anticancer activity of 2’-hydroxyflavanone towards lung cancer (2018) (21)
- A glutathione S-transferases isozyme (bGST 5.8) involved in the metabolism of 4-hydroxy-2-trans-nonenal is localized in bovine lens epithelium. (1996) (21)
- Activity of melphalan in combination with the glutathione transferase inhibitor sulfasalazine (2004) (20)
- Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane. (2012) (20)
- Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. (2010) (20)
- Comparative studies on the effect of butylated hydroxyanisole on glutathione and glutathione S-transferases in the tissues of male and female CD-1 mice. (1993) (20)
- Purification and characterization of human muscle glutathione S-transferases: evidence that glutathione S-transferase zeta corresponds to a locus distinct from GST1, GST2, and GST3. (1991) (20)
- Rabbit aorta glutathione S-transferases and their role in bioactivation of trinitroglycerin. (1996) (20)
- The relationship of doxorubicin binding to membrane lipids with drug resistance. (1992) (19)
- Fluorescence spectroscopic studies on interactions between liver annexin VI and nucleotides--a possible role for a tryptophan residue. (1997) (19)
- Defense of mouse red blood cells against oxidative damage by phenylhydrazine. Glutathione peroxidase and catalase deficiency. (1980) (19)
- Differential expression of alpha, mu and pi classes of isozymes of glutathione S-transferase in bovine lens, cornea, and retina. (1988) (19)
- Inhibition of human glutathione S-transferases by 2,4-dichlorophenoxyacetate (2,4-D) and 2,4,5-trichlorophenoxyacetate (2,4,5-T). (1985) (19)
- Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells. (2003) (18)
- The effect of copper on human and bovine lens and on human cultured lens epithelium enzymes. (1975) (18)
- Expression of glutathione S-transferase isoenzymes in human small cell lung cancer cell lines. (1988) (18)
- Purification and characterization of the two forms of glutathione S-transferase present in human lens. (1985) (17)
- Inhibition of human glutathione S-transferases by bile acids. (1988) (16)
- Mitogenic and drug-resistance mediating effects of PKCα require RLIP76 (2006) (15)
- Glutathione S-transferase of bovine iris and ciliary body: characterization of isoenzymes. (1989) (15)
- Binding of benzo(a)pyrene to rat lung glutathione S‐transferases in vivo (1985) (15)
- Anion-exchange high-performance liquid chromatography of glutathione S-transferases. Separation of the minor isoenzymes of human erythrocyte, heart and lung. (1986) (15)
- P300 regulates the human RLIP76 promoter activity and gene expression. (2013) (15)
- Purification and characterization of glutathione S-transferase of murine ovary and testis. (1993) (14)
- Attenuation of galactose cataract by low levels of dietary curcumin (2000) (14)
- Rat lung glutathione S-transferases: subunit structure and the interrelationship with the liver enzymes. (1985) (14)
- Adenovirus-Mediated Overexpression of Glutathione-S-Transferase Mitigates Transplant Arteriosclerosis in Rabbit Carotid Allografts (2010) (14)
- t-butylated hydroxytoluene enhances intracellular levels of glutathione and related enzymes of rat lens in vitro organ culture. (1992) (14)
- Reversal of melphalan resistance in vivo and in vitro by modulation of glutathione metabolism. (1991) (14)
- Inhibition of bovine lens glutathione S-transferases by hematin, bilirubin, and bromosulfophthalein. (1991) (14)
- Gender-related differences in expression of murine glutathione S-transferases and their induction by butylated hydroxyanisole. (1994) (13)
- Studies in neuronal ceroid lipofuscinosis: Enzymes of liver and brain tissues involved in the defense against oxidative damage (1982) (13)
- Comparative studies on the isoenzymes of glutathione S-transferase of rat brain and other tissues. (1987) (13)
- Glutathione S-transferase-catalyzed conjugation of 9,10-epoxystearic acid with glutathione. (1991) (13)
- Mechanisms for xenobiotic transport in biological membranes. (1999) (12)
- Glutathione 5-transferase and P-glycoprotein in multidrug resistant chinese hamster cells (1990) (12)
- Purification and functional reconstitution of intact ral-binding Gtpase activating protein, RLIP76, in artificial liposomes. (2001) (12)
- MPTP metabolites inhibit rat brain glutathione S-transferases (1987) (12)
- L-Dopa peroxidase activity of human erythrocyte catalase. (1977) (12)
- Glutathione S-transferase of mouse liver: sex-related differences in the expression of various isozymes. (1992) (11)
- Phase III detoxification system. (1993) (11)
- Interactions with glutathione S-transferases of porphyrins used in photodynamic therapy and naturally occurring porphyrins. (1985) (11)
- Physiological Substrates of Glutathione S-Transferases (2006) (11)
- Differential activities of rat and human lung glutathione S-transferase isoenzymes towards benzo(a)pyrene epoxides. (1985) (11)
- Characterization of two novel subunits of the α-class glutathione S-transferases of human liver (1993) (11)
- Studies in neuronal ceroid‐lipofuscinosis: Heterogeneous nature of neuronal autofluorescent lipopigments (1981) (11)
- Comparative effect of the induction of the subunits of rat liver glutathione S-transferases by butylated hydroxytoluene. (1984) (10)
- Studies on beta-D-N-acetylhexosaminidase. Various isozymes in tissues of normal subjects and Sandhoff's disease patients. (1975) (10)
- Immunocytochemical evidence for the expression of GST1, GST2, and GST3 gene loci for glutathione S-transferase in human lung (2007) (10)
- Two immunologically distinct Yc-type subunits are present in rat lung glutathione S-transferases. (1984) (10)
- RLIP 76 Transports Vinorelbine and Mediates Drug Resistance in Non – Small Cell Lung Cancer (2005) (10)
- Purification and characterization of glutathione S-transferases from rat pancreas. (1991) (9)
- Multiple transport proteins involved in the detoxification of endo- and xenobiotics. (1997) (9)
- Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human cancer xenografts in nude mice. (2011) (9)
- ATP-DRIVEN EFFLUX OF GLUTATHIONE S-CONJUGATES, ANTITUMOR DRUGS, AND XENOBIOTICS FROM HUMAN ERYTHROCYTES (1996) (9)
- Distribution of lysosomal hydrolases in human and bovine ocular tissues. (1981) (9)
- Studies on human beta-D-N-acetylhexosaminidases. I. Purification and properties. (1974) (9)
- Studies in neuronal ceroid-lipofuscinosis: leukocyte peroxidase deficiency in a patient with neuronal ceroid-lipofuscinosis (Jansky-Bielschowsky type). (1977) (8)
- Effect of 3,5-di-t-butyl-4-hydroxytoluene (BHT) on glutathione-linked detoxification mechanisms of rat ocular lens. (1985) (8)
- Doxorubicin transport by RALBP 1 and ABCG 2 in lung and breast cancer (8)
- Toxicity of oxidized beta-carotene to cultured human cells. (2005) (8)
- Is a Major Determinant of Radiation Sensitivity (2005) (8)
- Lens glutathione depletion of 1-chloro-2,4-dinitrobenzene and oxidative stress. (1984) (8)
- Glutathione S-Transferases as Modulators of Signal Transduction (2006) (8)
- Anionic glutathione S-transferases of human erythrocytes, placenta, and lung: evidence for structural differences. (1989) (8)
- Mitogenic and drug-resistance mediating effects of PKCalpha require RLIP76. (2006) (7)
- An alpha class mouse glutathione S-transferase with exceptional catalytic efficiency in the conjugation of glutathione with 7beta, 8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene. (1996) (7)
- RLIP 76 and Cancer (2008) (7)
- COMPARISON OF GLUTATHIONE S-TRANSFERASE ISOZYME PROFILES OF HUMAN LEUKEMIAK562, HL60 AND U937 CELLS (1999) (6)
- Purification and Characterization of Glutathione S-Transferases of Eoreuma loftini and Diatraea saccharalis (Lepidoptera: Pyralidae) (1991) (6)
- Purification and characterization of glutathione S-transferases from the bovine cornea. (1982) (6)
- Cystic Fibrosis. II. The Urinary Mucociliary Inhibitor (1982) (6)
- RLIP76 in AED drug resistance (2007) (6)
- Cationic glutathione S-transferase of human erythrocytes has unique kinetic characteristics among human glutathione S-transferases. (1986) (5)
- The interrelationship between P-glycoprotein and glutathionyl S-conjugate transporter(s) (1990) (5)
- DIFFERENTIAL STAINING OF HUMAN ERYTHROCYTE MEMBRANE PROTEINS BY COOMASSIE AND SILVER : IMPLICATIONS IN THE ASSESSMENT OF HOMOGENEITY OF MEMBRANE PROTE INS (1996) (5)
- Role of RLIP 76 in doxorubicin resistance in lung cancer ( Review ) (5)
- Glutathione-mediated detoxification mechanisms of human placenta. (1981) (5)
- POLYCLONAL ANTIBODIES SPECIFIC TO HUMAN GLUTATHIONE S-TRANSFERASE 5.8 (HGST 5.8) (1995) (5)
- Transfection of HLE B-3 Cells with hGSTA1 or hGSTA2 Protects Against Hydrogen Peroxide and Naphthalene Induced Lipid Peroxidation and Apoptosis* (2002) (5)
- Glutathione S-Transferase Isozyme Composition of HumanTissues (2006) (5)
- ATP dependent primary active transport of xenobiotic-glutathione conjugates by human erythrocyte membrane (2004) (4)
- β‐glucuronidase (2020) (4)
- Green Tea Cancer Prevention (2011) (4)
- Comparison of kinetic properties and expression of GST pi (GSTP1-1) in tissues of men and women (1994) (3)
- The effect of doxorubicin on the transport of glutathione conjugates from human erythrocytes (1991) (3)
- Lens specific RLIP76 transgenic mice show a phenotype similar to microphthalmia. (2014) (3)
- Glutathione S-transferase and P-glycoprotein in multidrug resistant Chinese hamster cells. (1990) (3)
- Rat GST 8-8 is expressed predominantly in myeloid origin cells infiltrating the gravid uterus. (1997) (3)
- Glutathione S-transferases of lung: purification and characterization of human lung glutathione S-transferases (2007) (3)
- Low and high Km forms of dinitrophenylglutathione-stimulated ATPase in bovine lens. (1993) (3)
- Low and High Km Forms of R;Regular Article Dinitrophenylglutathione-stimulated ATPase in Bovine Lens (1993) (3)
- PHASE III DETOXIFICATION SYSTEM. REPLY (1993) (2)
- The effect of t-butylated hydroxytoluene on glutathione linked detoxification mechanisms in rat (1983) (2)
- Qualitative and quantitative sex-related differences in glutathione S-transferases of mouse kidney (1993) (2)
- STRUCTURE, FUNCTION AND METABOLISM OF GLYCOSPHINGOLIPIDS (1980) (2)
- Ral-Binding Protein is Required for the Maturation and Function of Dendritic Cells (2010) (2)
- Effects of oxidative stress on human sperm activation (2003) (2)
- Immunochemical localization of glutathione S-transferases in rat lung (2007) (2)
- Glutathione S-transferases of human lung: Evidence that two distinct μ class subunits are expressed differentially in human population (1990) (2)
- A subgroup of class Cloning of eDNA for mouse glutathione S-transferases lung glutathione S-transferase GST 5.7 (1992) (1)
- Abstract 3330: Overcoming drug resistance in triple negative breast cancer by targeting SMC1 and PARP. (2013) (1)
- Mechanisms of Chemopreventive Activity of Sulforaphane (2014) (1)
- Characterization of a novel alpha-class anionic glutathione S-transferase isozyme from human liver. (1990) (1)
- Studies of Human Kidney y-Glutamyl Transpeptidase (2011) (1)
- Glutathione-linked pathways in drug resistance: Characterization and functional reconstitution of human erythrocyte glutathione-conjugate transporter (1999) (1)
- PHOTOAFFINITY-LABELING WITH 8-AZIDO[ALPHA-32P] ATP OF THE ATP-DEPENDENT GLUTATHIONE CONJUGATE TRANSPORTER IN CANALICULAR PLASMA-MEMBRANES FROM NORMAL WISTAR AND GY MUTANT RATS (1991) (1)
- Abstract 3702: 2-Hydroxyflavanone inhibits renal cancer growth by inhibiting tumor cell proliferation and angiogenesis (2011) (1)
- METABOLIC DISORDERS IN SPHINGOLIPIDOSES (1980) (1)
- Doxorubicin, daunorubicin and vinblastine are transported by a glutathione conjugate transporter: 9 (1994) (0)
- Abstract 5547: Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis (2011) (0)
- Modulation of 4-Hydroxy-2-Nonenal Induced Signaling by Glutathione S-Transferase A4-4 (2010) (0)
- Toxicity of Carotenoid Oxidative Breakdown Products to Cultured Human Retinal Pigmented Epithelial cells (2004) (0)
- Sphingolipid beta-D-galactosidases in globoid cell leukodystrophy (Krabbe disease). (1978) (0)
- Growth Guidance Cue (2011) (0)
- effect of glutathione depletion on hemoglobin dinitrobenzene: the fate of glutathione conjugate in erythrocytes and the Enzymatic conjugation of erythrocyte glutathione with 1-chloro-2,4- (2013) (0)
- Studies on human kidney γ glutamyl transpeptidase: purification and kinetic properties (1975) (0)
- The Role of RLIP76 in Dendritic Cell-Based Immunotherapies. (2009) (0)
- Studies on human beta-D-N-acetylhexosaminidases. II. Kinetic and structural properties. (1974) (0)
- Lowering of Constitutive 4–Hydroxynonenal Levels in Human Lens Epithelial Cells Leads to Profound Changes in Gene Expression (2005) (0)
- Characterization of a novel glutathione s transferase isoenzyme of mouse lung (1991) (0)
- Abstract 4210: Gsta4 modifies susceptibility to skin tumor development in mice and humans (2010) (0)
- Lens Specific Rlip76 Transgenic Mice Show Impaired Lens Development (2011) (0)
- Effect of 4-Hydroxynonenal on EGFR Mediated Signaling Pathway in RPE Cells (2010) (0)
- Lens GSH S-transferase: Post translational modification and role in the detoxification of xenobiotics (1980) (0)
- In vivo binding of benzo(a)pyrene to glutathione S-transferases of rat lung (1985) (0)
- Role of 4‐hydroxynonenal in oxidative stress induced signaling (2010) (0)
- Alternation in 4–Hydroxynonenal Homeostasis in Human Lens Epithelial Cell (HLE B–3)Leads to their Phenotypic Transformation (2004) (0)
- A Central Role of RLIP 76 in Regulation of Glycemic Control Running Title : Mechanisms of Insulin Resistance (2009) (0)
- FIFTH INTERNATIONAL CONGRESS OF HUMAN GENETICS: confirmation of the unique and common subunit theory (1976) (0)
- Enhanced Glutathione–S–Transferase (GST) Expression Protects Against Oxidative Stress In Retinal Pigment Epithelial (RPE) Cells (2004) (0)
- 4-Hydroxynonenal Activates Epidermal Growth Factor Receptor-linked Signaling Pathway to Protect RPE cells from Apoptosis (2010) (0)
- Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver. (1993) (0)
- Mitochondrial Glutathione S-Transferase Pool in Health and Disease (2006) (0)
- Role of 4-Hydroxynonenal in Oxidative Stress Induced Apoptotic Signaling in Retinal Pigment Epithelial (RPE) Cells (2010) (0)
- Purification and Properties of Human Kidney-Cortex Hexosaminiidases A and B (2005) (0)
- The expression and function of Vascular Endothelial Growth Factor in Retinal Pigment Epithelial (RPE) cells is regulated by4-Hydroxynonenal (HNE) and Glutathione s-transferase4-4 (2012) (0)
- Modulation ofcisplatin cytotoxicity bysulphasalazine (1994) (0)
- Multidrug-resistance conferred by RalBP1/RLIP76 (2005) (0)
- Subunit composition of glutathione S-transferases of rat lung. (1986) (0)
- 4-Hydroxynonenal Induced Activation of Nrf2 is Inhibited by Buthionine Sulfoximine (BSO) in NSCLC H358 cells (2010) (0)
- Interrelationship of hexosaminidase A and B: confirmation of the unique and common subunit theory (1976) (0)
- Correction: RLIP76: A Target for Kidney Cancer Therapy (2009) (0)
- Glutathione transferases: Old enzymes, new roles (2010) (0)
- Enzymology of Glutathione S-Transferases: Laboratory Methods (2006) (0)
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