Yamini Dalal
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Indian biochemist
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Yamini Dalalbiology Degrees
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Biochemistry
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Molecular Biology
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Biology
Yamini Dalal's Degrees
- Masters Biotechnology Delhi University
- Bachelors Biotechnology Delhi University
Why Is Yamini Dalal Influential?
(Suggest an Edit or Addition)According to Wikipedia, Yamini Dalal is an Indian American biochemist specialized in chromatin structure and epigenetic mechanisms. She is a senior investigator at the National Cancer Institute. Education Yamini Dalal became interested in chromosome structure and epigenetic gene regulation during her Baccalaureate years at St. Xavier's College, Mumbai where she earned a B.Sc. with a double major in Biochemistry and Life Sciences in 1995. She moved to the United States for her post-graduate work. In 's laboratory at Purdue University, she used classical chromatin biochemistry tools to understand how DNA sequence motifs and linker histones can shape the chromatin structure in silico, in vitro, and in vivo. During this time, she discovered that the regions of the mouse genome contained alternating tracts of stiff and flexible DNA, which allowed in silico prediction of nucleosome positions. These positions could be recapitulated in vitro using just purified histones and DNA, and detected in vivo, at developmentally regulated genes in mice. She also studied how linker histone H1 could influence nucleosome positioning and chromatin folding in vitro and in vivo. For these studies, she received her Ph.D. from Purdue University in 2003.
Yamini Dalal's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tetrameric Structure of Centromeric Nucleosomes in Interphase Drosophila Cells (2007) (245)
- Centromeric chromatin: what makes it unique? (2005) (163)
- A long non-coding RNA is required for targeting centromeric protein A to the human centromere (2014) (159)
- Structure, dynamics, and evolution of centromeric nucleosomes (2007) (146)
- Chaperone-mediated assembly of centromeric chromatin in vitro. (2006) (145)
- Cell-Cycle-Dependent Structural Transitions in the Human CENP-A Nucleosome In Vivo (2012) (140)
- CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells (2015) (110)
- Tetrameric organization of vertebrate centromeric nucleosomes (2010) (104)
- Histone variants: the tricksters of the chromatin world. (2014) (53)
- Chromatin Dynamics in Vivo: A Game of Musical Chairs (2015) (36)
- Internal modifications in the CENP-A nucleosome modulate centromeric dynamics (2017) (36)
- HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX (2018) (36)
- Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners (2018) (35)
- Single-epitope recognition imaging of native chromatin (2008) (32)
- Down the rabbit hole of centromere assembly and dynamics. (2010) (32)
- Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome (2015) (31)
- Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage (2010) (30)
- Promiscuous Histone Mis-Assembly Is Actively Prevented by Chaperones. (2016) (27)
- Epigenetic specification of centromeres. (2009) (26)
- The CENP-A nucleosome: a dynamic structure and role at the centromere (2012) (25)
- Binding Dynamics of Disordered Linker Histone H1 with a Nucleosomal Particle (2019) (20)
- Long-range oscillation in a periodic DNA sequence motif may influence nucleosome array formation (2005) (20)
- CENP-A octamers do not confer a reduction in nucleosome height by AFM (2014) (20)
- Through thick and thin: the conundrum of chromatin fibre folding in vivo (2012) (18)
- Circle ligation of in vitro assembled chromatin indicates a highly flexible structure. (2002) (18)
- The Art of War: harnessing the epigenome against cancer (2018) (17)
- The supercoiling state of DNA determines the handedness of both H3 and CENP-A nucleosomes. (2017) (17)
- The CENP-A nucleosome (2013) (16)
- CENP-A and H3 Nucleosomes Display a Similar Stability to Force-Mediated Disassembly (2016) (15)
- Tracking histone variant nucleosomes across the human cell cycle using biophysical, biochemical, and cytological analyses. (2014) (14)
- The Oligomerization Landscape of Histones (2018) (13)
- Disruption of the MSL complex inhibits tumor maintenance by exacerbating chromosomal instability (2021) (9)
- Minimal Cylinder Analysis Reveals the Mechanical Properties of Oncogenic Nucleosomes. (2019) (7)
- Addendum to: Histone variants: the tricksters of the chromatin world [Curr. Opin. Genet. Dev. 2014, 25:8–14] (2014) (7)
- Atomic Force Microscopy of Chromatin (2012) (7)
- Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin. (2020) (7)
- Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells (2022) (6)
- Correction: A long non-coding RNA is required for targeting centromeric protein A to the human centromere (2015) (5)
- NCI-CONNECT: Comprehensive Oncology Network Evaluating Rare CNS Tumors-Histone Mutated Midline Glioma Workshop Proceedings. (2020) (5)
- A glitch in the snitch: the role of linker histone H1 in shaping the epigenome in normal and diseased cells (2021) (5)
- DNA sequence alterations affect nucleosome array formation of the chicken ovalbumin gene. (2004) (5)
- CENP-A associated lncRNAs influence chromosome segregation in human cells (2017) (5)
- Faculty Opinions recommendation of Multi-input RNAi-based logic circuit for identification of specific cancer cells. (2011) (4)
- Identifying Centromeric RNAs Involved in Histone Dynamics In Vivo. (2016) (4)
- Job Opening for Nucleosome Mechanic: Flexibility Required (2020) (4)
- Faculty Opinions recommendation of CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. (2012) (3)
- Mechanical properties of nucleoprotein complexes determined by nanoindentation spectroscopy (2020) (3)
- Faculty Opinions recommendation of A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. (2013) (2)
- The ratio between centromeric proteins CENP-A and CENP-C maintains homeostasis of human centromeres (2019) (2)
- Faculty Opinions recommendation of Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation. (2011) (2)
- CENP-C stabilizes the conformation of CENP-A nucleosomes within the inner kinetochore at human centromeres (2019) (2)
- Signals in DNA that influence cromatin structure in vitro and in vivo (2003) (1)
- Correction: A long non-coding RNA is required for targeting centromeric protein A to the human centromere (2015) (1)
- Breaking the aging epigenetic barrier (2022) (1)
- Chromatin at the Intersection of Disease and Therapy (2012) (1)
- Mass Spectrometry-Based Methodology for Identification of Native Histone Variant Modifications From Mammalian Tissues and Solid Tumors. (2017) (1)
- Now you see it, now you don't: a biochemist's primer for advances in high-resolution microscopy: comment on "Biomolecular dynamics and binding studies in the living cell" by Stephan Diekmann and Christian Hoischen. (2014) (1)
- CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells (2015) (1)
- Faculty of 1000 evaluation for FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A. (2018) (1)
- The accessibility of human centromeric chromatin is modulated by elastic CENP-A nucleosomes (2019) (1)
- Cenp-A Hijacks the Histone Chaperone Network in Cancer--Computational Insights (2019) (0)
- Faculty Opinions recommendation of A 3D map of the yeast kinetochore reveals the presence of core and accessory centromere-specific histone. (2013) (0)
- Faculty Opinions recommendation of Intracellular nucleosomes constrain a DNA linking number difference of -1.26 that reconciles the Lk paradox. (2018) (0)
- Faculty Opinions recommendation of PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. (2011) (0)
- The life and times of the nucleus (2021) (0)
- The Binding Landscapes of the H 3 / H 4 and CENP-A / H 4 Dimers (2015) (0)
- Faculty Opinions recommendation of Crystal structure of the human centromeric nucleosome containing CENP-A. (2011) (0)
- Faculty Opinions recommendation of Spatial inter-centromeric interactions facilitated the emergence of evolutionary new centromeres. (2020) (0)
- Faculty Opinions recommendation of Video imaging of walking myosin V by high-speed atomic force microscopy. (2010) (0)
- Faculty Opinions recommendation of High-resolution visualization of H3 variants during replication reveals their controlled recycling. (2018) (0)
- Faculty Opinions recommendation of DNA topology and global architecture of point centromeres. (2016) (0)
- Two classes of chromatin domains are important for fidelity of human centromeres (2019) (0)
- The Binding Landscapes of the H3/H4 and CENP-A/H4 Dimers (2015) (0)
- Faculty Opinions recommendation of Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo. (2018) (0)
- Faculty Opinions recommendation of Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. (2011) (0)
- Faculty of 1000 evaluation for A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly. (2018) (0)
- Spotlights on Recent JACS Publications. (2018) (0)
- Faculty of 1000 evaluation for Essential role for centromeric factors following p53 loss and oncogenic transformation. (2018) (0)
- Faculty Opinions recommendation of Unconventional cell division cycles from marine-derived yeasts. (2019) (0)
- Faculty Opinions recommendation of A robust method for the purification and characterization of recombinant human histone H1 variants. (2019) (0)
- Faculty Opinions recommendation of Linking stochastic fluctuations in chromatin structure and gene expression. (2013) (0)
- Faculty Opinions recommendation of Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. (2020) (0)
- Faculty Opinions recommendation of Distinct influences of tandem repeats and retrotransposons on CENH3 nucleosome positioning. (2011) (0)
- The Handedness of Nucleosomes is Governed by the Supercoiling of DNA (2016) (0)
- Faculty Opinions recommendation of The genomic landscape of centromeres in various cancers. (2019) (0)
- Faculty Opinions recommendation of The prenucleosome, a stable conformational isomer of the nucleosome. (2016) (0)
- Mobility of nucleosomes is regulated by their binding partners (2022) (0)
- Faculty Opinions recommendation of Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining. (2013) (0)
- Computational Modeling of Nucleosomal Mechanics and Epigenetic Modifications (2020) (0)
- A Balance Between Elastic and Rigidified CENP-A Nucleosomes Govern Centromeric Chromatin Fidelity (2020) (0)
- Faculty Opinions recommendation of Circular ecDNA promotes accessible chromatin and high oncogene expression. (2019) (0)
- Decision letter: Archaeal chromatin ‘slinkies’ are inherently dynamic complexes with deflected DNA wrapping pathways (2021) (0)
- Bungee Jumping into Elasticity of Fragile Sites (2020) (0)
- A hyper-quiescent chromatin state formed during aging is reversed by regeneration (2023) (0)
- Faculty Opinions recommendation of Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels. (2019) (0)
- Faculty Opinions recommendation of Spt6 is a maintenance factor for centromeric CENP-A. (2020) (0)
- Faculty Opinions recommendation of Point centromere activity requires an optimal level of centromeric noncoding RNA. (2019) (0)
- Internal modifications in the CENP-A nucleosome modulate centromeric dynamics (2017) (0)
- Faculty Opinions recommendation of Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair. (2013) (0)
- Faculty Opinions recommendation of Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3. (2014) (0)
- Faculty Opinions recommendation of Localization atomic force microscopy. (2021) (0)
- Torque Mediated Kinetics of CENP-A Nucleosomes Reveals Resilience to Tension (2015) (0)
- The Molecular and Evolutionary Principles of Histone Folding in Eukarya and Archaea (2022) (0)
- Faculty Opinions recommendation of Structure and mechanism of the chromatin remodelling factor ISW1a. (2011) (0)
- Faculty Opinions recommendation of Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. (2011) (0)
- Elastic and Rigidified CENP-A Nucleosomes govern Centromeric Chromatin Plasticity (2018) (0)
- Diving into Chromatin across Space and Time. (2021) (0)
- Faculty Opinions recommendation of Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes. (2013) (0)
- A balance between elastic and rigidified chromatin states regulates transcriptional plasticity at human centromeres (2018) (0)
- EPIGENETIC MECHANISMS OF TISSUE AGING (2022) (0)
- Faculty of 1000 evaluation for PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. (2018) (0)
- Faculty of 1000 evaluation for Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. (2018) (0)
- Faculty Opinions recommendation of Active promoters give rise to false positive 'Phantom Peaks' in ChIP-seq experiments. (2015) (0)
- Alternative nucleosomal structure (2010) (0)
- A hyper-quiescent chromatin state formed during aging is reversed by regeneration. (2023) (0)
- Faculty Opinions recommendation of Short histone H2A variants: small in stature but not in function. (2020) (0)
- Modeling the binding of H-NS to DNA (2015) (0)
- Faculty Opinions recommendation of Telomere-to-telomere assembly of a complete human X chromosome. (2020) (0)
- Faculty Opinions recommendation of The role of the histone H3 variant CENPA in prostate cancer. (2020) (0)
- Faculty Opinions recommendation of Tension directly stabilizes reconstituted kinetochore-microtubule attachments. (2011) (0)
- Faculty Opinions recommendation of RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation. (2018) (0)
- Faculty Opinions recommendation of Islands of retroelements are the major components of Drosophila centromeres. (2019) (0)
- Single Molecule Analysis of CENP-A Chromatin by High-Speed Atomic Force Microscopy (2023) (0)
- The CENP-A nucleosome: a dynamic structure and role at the centromere (2012) (0)
- Faculty Opinions recommendation of Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture. (2020) (0)
- 9 Atomic Force Microscopy of Chromatin (2018) (0)
- Faculty Opinions recommendation of Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion. (2020) (0)
- Faculty Opinions recommendation of Ndc10 is a platform for inner kinetochore assembly in budding yeast. (2011) (0)
- Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability (2021) (0)
- “The Flexible Nucleosome: A Cross‐Kingdom Perspective” (2019) (0)
- Faculty Opinions recommendation of Chromatin's physical properties shape the nucleus and its functions. (2019) (0)
- Histone variant dynamics and epigenetics (2011) (0)
- Faculty Opinions recommendation of Massively parallel cantilever-free atomic force microscopy. (2021) (0)
- Faculty of 1000 evaluation for RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells. (2018) (0)
- Faculty Opinions recommendation of The nucleosome core particle remembers its position through DNA replication and RNA transcription. (2019) (0)
- Faculty Opinions recommendation of Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. (2013) (0)
- Faculty Opinions recommendation of ATRX-DAXX Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. (2019) (0)
- Faculty Opinions recommendation of Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer. (2019) (0)
- SESSION 1: DNA METHYLATION ACROSS GENOMES AND SPECIES (2015) (0)
- Faculty Opinions recommendation of H1 histones control the epigenetic landscape by local chromatin compaction. (2020) (0)
- Faculty Opinions recommendation of High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier. (2019) (0)
- The Symmetry and Asymmetry Behind Histone Folding Across Eukarya and Archaea (2023) (0)
- Faculty Opinions recommendation of A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy. (2019) (0)
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