Yishi Jin
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Neurobiologist
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Biology
Yishi Jin's Degrees
- PhD Neurobiology University of California, Berkeley
- Bachelors Biology Peking University
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Why Is Yishi Jin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Yishi Jin is a Chinese-American neurobiologist who is a professor at the Howard Hughes Medical Institute. She is interested in neural development and regeneration in nematode Caenorhabditis elegans. Jin is a Fellow of the American Association for the Advancement of Science, American Academy of Arts and Sciences and American Society for Cell Biology.
Yishi Jin's Published Works
Published Works
- A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms (2011) (723)
- Neurosurgery: Functional regeneration after laser axotomy (2004) (563)
- The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans (1999) (379)
- Intrinsic Control of Axon Regeneration (2010) (374)
- Regulation of a DLK-1 and p38 MAP Kinase Pathway by the Ubiquitin Ligase RPM-1 Is Required for Presynaptic Development (2005) (338)
- The DLK-1 Kinase Promotes mRNA Stability and Local Translation in C. elegans Synapses and Axon Regeneration (2009) (334)
- Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans (1995) (311)
- Distinct Innate Immune Responses to Infection and Wounding in the C. elegans Epidermis (2008) (277)
- Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase (2010) (263)
- The Caenorhabditis elegans Gene unc-25Encodes Glutamic Acid Decarboxylase and Is Required for Synaptic Transmission But Not Synaptic Development (1999) (259)
- Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein (1994) (247)
- Regulation of Presynaptic Terminal Organization by C. elegans RPM-1, a Putative Guanine Nucleotide Exchanger with a RING-H2 Finger Domain (2000) (229)
- UNC-16, a JNK-Signaling Scaffold Protein, Regulates Vesicle Transport in C. elegans (2001) (224)
- SYD-2 Liprin-α organizes presynaptic active zone formation through ELKS (2006) (207)
- Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching (2007) (207)
- LRK-1, a C. elegans PARK8-Related Kinase, Regulates Axonal-Dendritic Polarity of SV Proteins (2007) (195)
- The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination (2001) (188)
- Molecular mechanisms of presynaptic differentiation. (2008) (186)
- Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG (2012) (182)
- Axon Regeneration Pathways Identified by Systematic Genetic Screening in C. elegans (2011) (177)
- Coordinated Transcriptional Regulation of the unc-25Glutamic Acid Decarboxylase and the unc-47 GABA Vesicular Transporter by the Caenorhabditis elegans UNC-30 Homeodomain Protein (1999) (168)
- Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI) (2013) (158)
- lin-14 regulates the timing of synaptic remodelling in Caenorhabditis elegans (1998) (156)
- The AHR-1 aryl hydrocarbon receptor and its co-factor the AHA-1 aryl hydrocarbon receptor nuclear translocator specify GABAergic neuron cell fate in C. elegans (2004) (136)
- C. elegans RPM-1 Regulates Axon Termination and Synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1 (2007) (128)
- Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration. (2012) (125)
- A Neuronal Acetylcholine Receptor Regulates the Balance of Muscle Excitation and Inhibition in Caenorhabditis elegans (2009) (122)
- SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans (2002) (118)
- The Basement Membrane Components Nidogen and Type XVIII Collagen Regulate Organization of Neuromuscular Junctions inCaenorhabditis elegans (2003) (117)
- The Two Isoforms of the Caenorhabditis elegans Leukocyte-Common Antigen Related Receptor Tyrosine Phosphatase PTP-3 Function Independently in Axon Guidance and Synapse Formation (2005) (117)
- Roles of endosomal trafficking in neurite outgrowth and guidance. (2009) (115)
- The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization. (2004) (115)
- MAX-1, a Novel PH/MyTH4/FERM Domain Cytoplasmic Protein Implicated in Netrin-Mediated Axon Repulsion (2002) (110)
- Expression Profiling of GABAergic Motor Neurons in Caenorhabditis elegans (2005) (104)
- Regulation of DLK-1 Kinase Activity by Calcium-Mediated Dissociation from an Inhibitory Isoform (2012) (94)
- UNC-71, a disintegrin and metalloprotease (ADAM) protein, regulates motor axon guidance and sex myoblast migration in C. elegans (2003) (81)
- Excitatory motor neurons are local oscillators for backward locomotion (2017) (77)
- Palmitoylation controls DLK localization, interactions and activity to ensure effective axonal injury signaling (2015) (76)
- Intermediate filaments are required for C. elegans epidermal elongation. (2004) (76)
- Presynaptic terminal differentiation: transport and assembly (2004) (74)
- Plasma-mediated ablation: an optical tool for submicrometer surgery on neuronal and vascular systems. (2009) (74)
- The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans (2016) (70)
- The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration (2010) (69)
- Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics (2013) (67)
- C. elegans ankyrin repeat protein VAB-19 is a component of epidermal attachment structures and is essential for epidermal morphogenesis (2003) (66)
- Conserved Function of Caenorhabditis elegansUNC-30 and Mouse Pitx2 in Controlling GABAergic Neuron Differentiation (2001) (65)
- Liprin-α/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans (2013) (58)
- The microtubule minus-end-binding protein patronin/PTRN-1 is required for axon regeneration in C. elegans. (2014) (55)
- Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain (1990) (54)
- Synaptogenesis: insights from worm and fly (2002) (54)
- The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology (2013) (49)
- A Neuronal piRNA Pathway Inhibits Axon Regeneration in C. elegans (2018) (48)
- The Liprin Homology Domain Is Essential for the Homomeric Interaction of SYD-2/Liprin-α Protein in Presynaptic Assembly (2011) (46)
- Genetic dissection of axon regeneration (2011) (46)
- Context Specificity of Stress-activated Mitogen-activated Protein (MAP) Kinase Signaling: The Story as Told by Caenorhabditis elegans* (2016) (45)
- Cellular and molecular determinants targeting the Caenorhabditis elegans PHR protein RPM‐1 to perisynaptic regions (2008) (43)
- Dynamic Microtubules Drive Circuit Rewiring in the Absence of Neurite Remodeling (2015) (42)
- Caenorhabditis elegans Flamingo Cadherin fmi-1 Regulates GABAergic Neuronal Development (2012) (41)
- Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase (2015) (40)
- TRPM Channels Modulate Epileptic-like Convulsions via Systemic Ion Homeostasis (2011) (39)
- Genetic analysis of synaptic target recognition and assembly (2004) (38)
- Inhibition of Axon Regeneration by Liquid-like TIAR-2 Granules (2019) (37)
- Neuropeptides Function in a Homeostatic Manner to Modulate Excitation-Inhibition Imbalance in C. elegans (2013) (37)
- RAE-1, a Novel PHR Binding Protein, Is Required for Axon Termination and Synapse Formation in Caenorhabditis elegans (2012) (37)
- The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons. (2015) (37)
- The JIP3 scaffold protein UNC‐16 regulates RAB‐5 dependent membrane trafficking at C. elegans synapses (2009) (36)
- Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration (2018) (34)
- Microtubule-dependent ribosome localization in C. elegans neurons (2017) (33)
- The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans (2006) (33)
- Getting a GRIP on Liprins (2002) (32)
- S6 Kinase Inhibits Intrinsic Axon Regeneration Capacity via AMP Kinase in Caenorhabditis elegans (2014) (32)
- Neuronal responses to stress and injury in C. elegans (2015) (32)
- The EBAX-type Cullin-RING E3 Ligase and Hsp90 Guard the Protein Quality of the SAX-3/Robo Receptor in Developing Neurons (2013) (32)
- A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density (2016) (32)
- Motor Neuron Synapse and Axon Defects in a C. elegans Alpha-Tubulin Mutant (2010) (31)
- Optogenetic mutagenesis in Caenorhabditis elegans (2015) (31)
- Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS (2018) (30)
- Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons (2016) (27)
- Axon regeneration in C. elegans (2014) (27)
- Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear Translocation. (2017) (26)
- RIMB-1/RIM-Binding Protein and UNC-10/RIM Redundantly Regulate Presynaptic Localization of the Voltage-Gated Calcium Channel in Caenorhabditis elegans (2019) (26)
- Hyperactivation of B-Type Motor Neurons Results in Aberrant Synchrony of the Caenorhabditis elegans Motor Circuit (2013) (26)
- Rabx-5 Regulates RAB-5 Early Endosomal Compartments and Synaptic Vesicles in C. elegans (2012) (25)
- Coordinated inhibition of C/EBP by Tribbles in multiple tissues is essential for Caenorhabditis elegans development (2016) (25)
- Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans. (2019) (25)
- Neural circuit rewiring: insights from DD synapse remodeling (2016) (24)
- CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins (2016) (23)
- SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) Function Interdependently to Promote Axon Guidance by Regulating the MIG-2 GTPase (2015) (21)
- A Ubiquitin E2 Variant Protein Acts in Axon Termination and Synaptogenesis in Caenorhabditis elegans (2010) (21)
- Nuclear pre-mRNA 3′-end processing regulates synapse and axon development in C. elegans (2010) (21)
- Nerve regeneration in C. elegans after femtosecond laser axotomy (2005) (19)
- Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel (2016) (19)
- The C2H2 zinc-finger protein SYD-9 is a putative posttranscriptional regulator for synaptic transmission (2006) (19)
- Neuronal differentiation in C. elegans. (2005) (19)
- Faculty of 1000 evaluation for piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. (2018) (18)
- Asynchronous Cholinergic Drive Correlates with Excitation-Inhibition Imbalance via a Neuronal Ca2+ Sensor Protein. (2017) (18)
- Systematic Analyses of rpm-1 Suppressors Reveal Roles for ESS-2 in mRNA Splicing in Caenorhabditis elegans (2014) (17)
- Intermediate filament accumulation can stabilize microtubules in Caenorhabditis elegans motor neurons (2018) (17)
- Regulation of neuronal axon specification by glia-neuron gap junctions in C. elegans (2016) (17)
- Cholinergic transmission in C. elegans: Functions, diversity, and maturation of ACh‐activated ion channels (2020) (17)
- Multitasking: Dual Leucine Zipper-Bearing Kinases in Neuronal Development and Stress Management. (2019) (16)
- DIP-2 suppresses ectopic neurite sprouting and axonal regeneration in mature neurons (2019) (16)
- The mRNA Decay Factor CAR-1/LSM14 Regulates Axon Regeneration via Mitochondrial Calcium Dynamics (2020) (15)
- Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development (2017) (15)
- Targeted Mutagenesis of Duplicated Genes in Caenorhabditis elegans Using CRISPR-Cas9. (2016) (14)
- Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans (2017) (14)
- Advances in synapse formation: forging connections in the worm (2015) (13)
- A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans (2017) (13)
- Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17 (2020) (13)
- Building stereotypic connectivity: mechanistic insights into structural plasticity from C. elegans (2018) (13)
- Liprin-alpha/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans (2019) (13)
- Shaping neurodevelopment: distinct contributions of cytoskeletal proteins (2018) (11)
- Rapid Integration of Multi-copy Transgenes Using Optogenetic Mutagenesis in Caenorhabditis elegans (2018) (11)
- Pharming for Genes in Neurotransmission: Combining Chemical and Genetic Approaches in Caenorhabditis elegans. (2018) (10)
- Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans (2017) (9)
- Gap junctions: historical discoveries and new findings in the Caenorhabditis elegans nervous system (2020) (8)
- Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development (2015) (7)
- Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics (2015) (7)
- Regulatory roles of RNA binding proteins in the nervous system of C. elegans (2015) (7)
- Expanding views of presynaptic terminals: new findings from Caenorhabditis elegans (2012) (6)
- A Critical Role for DLK and LZK in Axonal Repair in the Mammalian Spinal Cord (2022) (6)
- Caenorhabditis Elegans Junctophilin has Tissue-Specific Functions and Regulates Neurotransmission with Extended-Synaptotagmin (2020) (6)
- C. elegans MAGU-2/Mpp5 homolog regulates epidermal phagocytosis and synapse density (2020) (5)
- Distinct cis elements in the 3' UTR of the C. elegans cebp-1 mRNA mediate its regulation in neuronal development. (2017) (5)
- Junctophilins: Key Membrane Tethers in Muscles and Neurons (2021) (5)
- The Function of a Spindle Checkpoint Gene bub-1 in C. elegans Development (2009) (5)
- Neuronal transcriptome analyses reveal novel neuropeptide modulators of excitation and inhibition imbalance in C. elegans (2019) (5)
- Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity (2021) (5)
- Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1. (2010) (4)
- Wired for insight—recent advances in Caenorhabditis elegans neural circuits (2021) (4)
- Functional Dissection of C. elegans bZip-Protein CEBP-1 Reveals Novel Structural Motifs Required for Axon Regeneration and Nuclear Import (2019) (4)
- Excitatory Motor Neurons are Local Central Pattern Generators in an Anatomically Compressed Motor Circuit for Reverse Locomotion (2017) (4)
- Isolation and characterization of a novel member of the ACC ligand-gated chloride channel family, Hco-LCG-46, from the parasitic nematode Haemonchus contortus. (2020) (3)
- Nematode C. elegans: Genetic Dissection of Pathways Regulating Seizure and Epileptic-Like Behaviors (2017) (3)
- Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer (2018) (3)
- Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans. (2016) (3)
- Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model (2016) (3)
- Spatial and temporal dynamics of neurite regrowth (2013) (3)
- Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength (2020) (3)
- EOR-1 and EOR-2 function in RMED/V neuron specification (2019) (2)
- New mutants defective in RMED/V neuron specification are alleles of EOR-1 and EOR-2 (2019) (2)
- PHR (Pam/Highwire/RPM-1) (2009) (1)
- Systematic analyses of rpm-1 suppressors reveal roles for ESS-2 in mRNA splicing in C . elegans (2014) (1)
- Molecular and genetic approaches for the analysis of C. elegans neuronal development. (2011) (1)
- Ground Control to Major Tom: The Cell Body Signals Axon Degeneration (2016) (1)
- The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1. (2022) (1)
- Forward genetic screening identifies novel roles for N-terminal acetyltransferase C and histone deacetylase in C. elegans development (2022) (1)
- Novel actions of arecoline in the C. elegans motor circuit (2020) (1)
- The muscarinic agonist arecoline suppresses motor circuit hyperactivity in C. elegans (2020) (1)
- C. elegans VWA-8 is a mitochondrial protein (2020) (1)
- Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans. (2023) (1)
- Author response: Microtubule-dependent ribosome localization in C. elegans neurons (2017) (1)
- The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology (2013) (1)
- Nerve Regeneration in C. elegans after Femtosecond Laser Nano-Surgery (2005) (1)
- Femtosecond Laser Ablation of Axons and the Subsequent Neural Regrowth (2005) (0)
- Erratum to: Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics (2015) (0)
- A mutation linked to degt-1(ok3307) in C. elegans strain VC2633 affects rpm-1 (2022) (0)
- Intragenic suppressors of unc-104 ( e1265 ) identify potential roles of the conserved stalk region (2022) (0)
- to Infection and Wounding Supplemental Data S 1 Distinct Innate Immune Responses in the C . elegans Epidermis (0)
- Function of the Family Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. (2016) (0)
- Executing cell-specific cross-linking immunoprecipitation and sequencing (seCLIP) in C. elegans (2022) (0)
- Multiple Roles of RNA Regulatory Factors in Neuronal Development and Function in C. elegans (2018) (0)
- Faculty Opinions recommendation of Transgenerational transmission of environmental information in C. elegans. (2017) (0)
- Coordinated inhibition of C/EBP by Tribbles in multiple tissues is essential for Caenorhabditis elegans development (2016) (0)
- Erratum to: Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics (2015) (0)
- Nerve regeneration after femtosecond laser nanosurgery (2005) (0)
- A Neuronal piRNA Pathwa y Inhibits Axon Regeneration in C . elegans Graphical (2018) (0)
- A Novel Axon Guidance Defective Caenorhabditis elegans (2001) (0)
- The roles of mitogen-activated protein kinase ( MAPK ) pathway in axon regeneration (2011) (0)
- Author response: Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration (2018) (0)
- EOR-1 and EOR-2 act independently of RAS and WNT signaling pathways in RMED/V neuron specification (2019) (0)
- Faculty Opinions recommendation of Functional analysis of neuronal microRNAs in Caenorhabditis elegans dauer formation by combinational genetics and Neuronal miRISC immunoprecipitation. (2013) (0)
- Development of the Drosophila and C. Elegans Neuromuscular Junctions (2006) (0)
- Correction: Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength (2023) (0)
- UEV-3, a ubiquitin conjugating enzyme E2 variant, functions in the p38 MAP kinase pathway for synaptogenesis (2007) (0)
- Intrinsic regulators of neuronal regeneration in C. elegans (2019) (0)
- Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Acyltransferase ZDHHC17. (2021) (0)
- Wired For Insight- Recent Advance in C. elegans Neural Circuits (2021) (0)
- The basic helix-loop-helix (bHLH) proteins define a large family of structurally similar transcription factors that function in a variety of developmental processes including myogenesis (2000) (0)
- A Ubiquitin E 2 Variant Protein Acts in Axon Termination and Synaptogenesis in C . elegans (2010) (0)
- In Vivo Analysis of a Biomolecular Condensate in the Nervous System of C. elegans. (2023) (0)
- A null mutation of C. elegans vwa-8 (2020) (0)
- Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics (2015) (0)
- Nerve Regeneration Following Femtosecond Laser Nano-Axotomy (2005) (0)
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