Yoram Vodovotz

Yoram Vodovotz's AcademicInfluence.com Rankings

Yoram Vodovotz

Engineering

#4879

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#6104

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Bioengineering

#51

World Rank

#53

Historical Rank

Biomedical Engineering

#337

World Rank

#346

Historical Rank

Applied Physics

#1295

World Rank

#1324

Historical Rank

engineering Degrees

Yoram Vodovotz

Biology

#9311

World Rank

#12500

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Systems Biology

#22

World Rank

#22

Historical Rank

Computational Biology

#180

World Rank

#181

Historical Rank

biology Degrees

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Engineering
Biology

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Yoram Vodovotz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Macrophage deactivation by interleukin 10 (1991) (1302)
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta (1993) (713)
The multifaceted roles of nitric oxide in cancer. (1998) (677)
Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis. (2019) (572)
Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. (1992) (570)
The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide. (1998) (396)
Inducible Nitric Oxide Synthase and Inflammatory Diseases (2000) (392)
Nitric oxide and wound repair: role of cytokines? (2002) (334)
Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. (2006) (306)
Hemorrhagic Shock Induces NAD(P)H Oxidase Activation in Neutrophils: Role of HMGB1-TLR4 Signaling1 (2007) (293)
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease (1996) (290)
The dynamics of acute inflammation. (2004) (287)
Agent‐based models in translational systems biology (2009) (282)
Mechanism of suppression of nitric oxide synthase expression by interleukin‐4 in primary mouse macrophages (1994) (268)
A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. (2006) (264)
Role of Toll-Like Receptors in Changes in Gene Expression and NF-κB Activation in Mouse Hepatocytes Stimulated with Lipopolysaccharide (2002) (247)
Translational Systems Biology of Inflammation (2008) (238)
Systemic inflammation and remote organ injury following trauma require HMGB1. (2007) (212)
The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO. (1998) (208)
THE ACUTE INFLAMMATORY RESPONSE IN DIVERSE SHOCK STATES (2005) (206)
In silico design of clinical trials: A method coming of age (2004) (193)
Superoxide Modulates the Oxidation and Nitrosation of Thiols by Nitric Oxide-derived Reactive Intermediates (1997) (190)
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase (2005) (189)
A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration. (2006) (175)
Convenient colorimetric and fluorometric assays for S-nitrosothiols. (1996) (163)
The Chemical Biology of Nitric Oxide (2002) (155)
Nitric oxide, a protective molecule in the cardiovascular system. (2013) (154)
Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models. (2000) (147)
Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study (2010) (147)
Agent‐based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor‐β1 (2007) (144)
Vesicle membrane association of nitric oxide synthase in primary mouse macrophages. (1995) (143)
Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide. (1994) (142)
Mechanistic simulations of inflammation: current state and future prospects. (2009) (141)
Mathematical models of the acute inflammatory response (2004) (138)
Regulation of Transforming Growth Factor β1 by Nitric Oxide (1999) (137)
Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes. (1992) (135)
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse (1996) (133)
Nitric oxide and some nitric oxide donor compounds enhance the cytotoxicity of cisplatin. (1997) (125)
Peroxisomal localization of inducible nitric oxide synthase in hepatocytes (2002) (124)
Antioxidant effects of nitric oxide. (1999) (120)
A Patient-Specific in silico Model of Inflammation and Healing Tested in Acute Vocal Fold Injury (2008) (119)
Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock. (2006) (117)
Control of nitric oxide production by transforming growth factor-beta1: mechanistic insights and potential relevance to human disease. (1997) (116)
IN SILICO MODELS OF ACUTE INFLAMMATION IN ANIMALS (2006) (114)
Nitric Oxide and Ionizing Radiation Synergistically Promote Apoptosis and Growth Inhibition of Cancer by Activating p53 (2004) (114)
Temporal Patterns of Circulating Inflammation Biomarker Networks Differentiate Susceptibility to Nosocomial Infection Following Blunt Trauma in Humans. (2016) (114)
Sepsis: Something old, something new, and a systems view. (2012) (111)
Liver Preservation With Machine Perfusion and a Newly Developed Cell‐Free Oxygen Carrier Solution Under Subnormothermic Conditions (2015) (110)
EARLY AIRWAY PRESSURE RELEASE VENTILATION PREVENTS ARDS—A NOVEL PREVENTIVE APPROACH TO LUNG INJURY (2013) (106)
Mammalian Target of Rapamycin Inhibition and Alloantigen-Specific Regulatory T Cells Synergize To Promote Long-Term Graft Survival in Immunocompetent Recipients (2009) (100)
Systemic inflammation and remote organ damage following bilateral femur fracture requires Toll-like receptor 4. (2006) (98)
A Dynamic View of Trauma/Hemorrhage-Induced Inflammation in Mice: Principal Drivers and Networks (2011) (95)
The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury (2014) (92)
Analysis of Serum Inflammatory Mediators Identifies Unique Dynamic Networks Associated with Death and Spontaneous Survival in Pediatric Acute Liver Failure (2013) (85)
PATTERNS OF CYTOKINE RELEASE AND EVOLUTION OF REMOTE ORGAN DYSFUNCTION AFTER BILATERAL FEMUR FRACTURE (2008) (85)
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation. (2006) (84)
THE ROLE OF INITIAL TRAUMA IN THE HOST'S RESPONSE TO INJURY AND HEMORRHAGE: INSIGHTS FROM A CORRELATION OF MATHEMATICAL SIMULATIONS AND HEPATIC TRANSCRIPTOMIC ANALYSIS (2006) (84)
Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling‐1–dependent mechanism (2009) (83)
Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow‐derived cells and parenchymal cells (2008) (83)
Resetting the transcription factor network reverses terminal chronic hepatic failure. (2015) (82)
Central Role for MCP-1/CCL2 in Injury-Induced Inflammation Revealed by In Vitro, In Silico, and Clinical Studies (2013) (82)
Control of nitric oxide synthase expression by transforming growth factor-beta: implications for homeostasis. (1994) (81)
The Acute Inflammatory Response in Trauma / Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects (2009) (81)
The role of nitric oxide chemistry in cancer treatment. (1998) (79)
Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies. (2004) (79)
In Silico and In Vivo Approach to Elucidate the Inflammatory Complexity of CD14-deficient Mice (2006) (78)
Autologous nitric oxide protects mouse and human keratinocytes from ultraviolet B radiation-induced apoptosis. (2003) (75)
Translational Systems Approaches to the Biology of Inflammation and Healing (2010) (74)
Trauma in silico: Individual-specific mathematical models and virtual clinical populations (2015) (74)
Multiplex analysis of urinary cytokine levels in rat model of cyclophosphamide-induced cystitis. (2009) (74)
A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine* (2012) (73)
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model (2017) (73)
Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome: A novel timing-based ventilatory intervention to avert lung injury (2012) (72)
Selective Expansion of Allogeneic Regulatory T Cells by Hepatic Stellate Cells: Role of Endotoxin and Implications for Allograft Tolerance (2012) (70)
Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. (2009) (70)
Mammalian Transforming Growth Factor β1 Activated after Ingestion by Anopheles stephensi Modulates Mosquito Immunity (2003) (70)
Regulation of transforming growth factor beta1 by nitric oxide. (1999) (69)
Adenoviral Gene Transfer of the Human Inducible Nitric Oxide Synthase Gene Enhances the Radiation Response of Human Colorectal Cancer Associated with Alterations in Tumor Vascularity (2004) (69)
Translational Systems Biology: Introduction of an Engineering Approach to the Pathophysiology of the Burn Patient (2008) (68)
Hepatocyte toll-like receptor 2 expression in vivo and in vitro: role of cytokines in induction of rat TLR2 gene expression by lipopolysaccharide. (2000) (68)
The oxidative and nitrosative chemistry of the nitric oxide/superoxide reaction in the presence of bicarbonate. (1999) (67)
Characterization of the Expression of Inducible Nitric Oxide Synthase in Rat and Human Liver During Hemorrhagic Shock (2003) (67)
Traces of bacterial lipopolysaccharide suppress IFN-gamma-induced nitric oxide synthase gene expression in primary mouse macrophages. (1993) (66)
Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-Derived Mediators from Computational Models of Trauma-Induced Inflammation. (2015) (65)
Mechanisms of Hepatoprotection by Nitric Oxide (2002) (65)
An agent-based model of inflammation and fibrosis following particulate exposure in the lung. (2011) (65)
Airway pressure release ventilation prevents ventilator-induced lung injury in normal lungs. (2013) (64)
The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis (2012) (63)
Computational Analysis Supports an Early, Type 17 Cell-Associated Divergence of Blunt Trauma Survival and Mortality* (2016) (63)
An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction. (2008) (62)
A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion. (2002) (61)
Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes. (2005) (61)
The hepatocyte as a microbial product-responsive cell (2001) (60)
Using a Mathematical Model to Analyze the Role of Probiotics and Inflammation in Necrotizing Enterocolitis (2009) (60)
Translational systems biology of inflammation: potential applications to personalized medicine. (2010) (60)
A MATHEMATICAL SIMULATION OF THE INFLAMMATORY RESPONSE TO ANTHRAX INFECTION (2008) (59)
Detection of S-nitrosothiols by fluorometric and colorimetric methods. (1999) (59)
In Silico Modeling: Methods and Applications to Trauma and Sepsis (2013) (59)
An Adequately Robust Early TNF-α Response Is a Hallmark of Survival Following Trauma/Hemorrhage (2009) (57)
Immunocytochemical localization of latent transforming growth factor‐β1 activation by stimulated macrophages (1999) (56)
Systems biology and inflammation. (2010) (56)
Hepatic Stellate Cells Undermine the Allostimulatory Function of Liver Myeloid Dendritic Cells via STAT3-Dependent Induction of IDO (2012) (55)
Evidence-based modeling of critical illness: an initial consensus from the Society for Complexity in Acute Illness. (2007) (55)
Effects of intracoronary radiation on thrombosis after balloon overstretch injury in the porcine model. (1999) (55)
Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma (2015) (55)
Computational and systems biology in trauma and sepsis: current state and future perspectives. (2012) (54)
Hemoadsorption Reprograms Inflammation in Experimental Gram-negative Septic Peritonitis: Insights from In Vivo and In Silico Studies (2012) (54)
Removal of Inflammatory Ascites Is Associated With Dynamic Modification of Local and Systemic Inflammation Along With Prevention of Acute Lung Injury: In Vivo and In Silico Studies (2014) (53)
Translational systems biology of inflammation and healing (2010) (52)
Deciphering the complexity of acute inflammation using mathematical models (2006) (52)
Nitric Oxide and Inflammation (2012) (52)
MATHEMATICAL MODELING OF POSTHEMORRHAGE INFLAMMATION IN MICE: STUDIES USING A NOVEL, COMPUTER-CONTROLLED, CLOSED-LOOP HEMORRHAGE APPARATUS (2009) (51)
In silico augmentation of the drug development pipeline: examples from the study of acute inflammation (2011) (51)
A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression (2014) (51)
Inducible Protein-10, a Potential Driver of Neurally Controlled Interleukin-10 and Morbidity in Human Blunt Trauma* (2014) (51)
Prehospital Hypotension Is Associated With Altered Inflammation Dynamics and Worse Outcomes Following Blunt Trauma in Humans* (2015) (50)
Interacting Neuroendocrine and Innate and Acquired Immune Pathways Regulate Neutrophil Mobilization from Bone Marrow following Hemorrhagic Shock1 (2009) (50)
The Role of Fracture-Associated Soft Tissue Injury in the Induction of Systemic Inflammation and Remote Organ Dysfunction After Bilateral Femur Fracture (2008) (49)
Precision Medicine for Critical Illness and Injury (2016) (48)
Individual-specific principal component analysis of circulating inflammatory mediators predicts early organ dysfunction in trauma patients. (2016) (48)
SPARK: a framework for multi-scale agent-based biomedical modeling (2010) (47)
Lack of the Receptor for Advanced Glycation End-Products Attenuates E. coli Pneumonia in Mice (2011) (47)
Challenges and rewards on the road to translational systems biology in acute illness: four case reports from interdisciplinary teams. (2007) (46)
Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia (2012) (46)
Overexpression of the human inducible nitric oxide synthase gene enhances radiation-induced apoptosis in colorectal cancer cells via a caspase-dependent mechanism. (2003) (45)
Roles of dendritic cells in murine hepatic warm and liver transplantation‐induced cold ischemia/reperfusion injury (2013) (45)
Injury‐induced MRP8/MRP14 stimulates IP‐10/CXCL10 in monocytes/macrophages (2015) (45)
Nitric Oxide Suppresses the Expression of Bcl-2 Binding Protein BNIP3 in Hepatocytes* (2001) (44)
Toward Computational Identification of Multiscale “Tipping Points” in Acute Inflammation and Multiple Organ Failure (2012) (44)
Ionizing radiation potentiates the induction of nitric oxide synthase by IFN‐γ and/or LPS in murine macrophage cell lines: role of TNF‐α (1998) (42)
LOCAL EXPOSURE OF BONE COMPONENTS TO INJURED SOFT TISSUE INDUCES TOLL-LIKE RECEPTOR 4-DEPENDENT SYSTEMIC INFLAMMATION WITH ACUTE LUNG INJURY (2008) (42)
Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-beta1. (2007) (39)
A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior. (2009) (39)
Data-Driven Modeling for Precision Medicine in Pediatric Acute Liver Failure (2016) (39)
HEPATOCYTES ENHANCE EFFECTS OF LIPOPOLYSACCHARIDE ON LIVER NONPARENCHYMAL CELLS THROUGH CLOSE CELL INTERACTIONS (2005) (39)
Inducible nitric oxide production and expression of transforming growth factor-beta1 in serum and CSF after cerebral ischaemic stroke in man. (1998) (38)
Complex Systems and Computational Biology Approaches to Acute Inflammation (2013) (38)
Hybrid Equation/Agent-Based Model of Ischemia-Induced Hyperemia and Pressure Ulcer Formation Predicts Greater Propensity to Ulcerate in Subjects with Spinal Cord Injury (2013) (38)
Linking Inflammation, Cardiorespiratory Variability, and Neural Control in Acute Inflammation via Computational Modeling (2012) (38)
Prehospital plasma is associated with distinct biomarker expression following injury. (2020) (38)
Increased mortality, blunted production of nitric oxide, and increased production of TNF‐α in endotoxemic TGF‐β1 transgenic mice (1998) (38)
Cytokine regulation of nitric oxide synthase in mouse retinal pigment epithelial cells in culture. (1994) (37)
The Acute Inflammatory Response in Trauma /Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects (2008) (37)
Systemic arginine depletion after a murine model of surgery or trauma. (2012) (36)
EARLY GROWTH RESPONSE 1 MEDIATES THE SYSTEMIC AND HEPATIC INFLAMMATORY RESPONSE INITIATED BY HEMORRHAGIC SHOCK (2007) (35)
A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury (2013) (35)
Granulomatous 'foreign body reactions' contribute to exaggerated in-stent restenosis. (1999) (35)
Control of nitric oxide production by endogenous TGF‐β1 and systemic nitric oxide in retinal pigment epithelial cells and peritoneal macrophages (1996) (35)
The role of hepatic type 1 plasminogen activator inhibitor (PAI‐1) during murine hemorrhagic shock (2005) (35)
How Implementation of Systems Biology into Clinical Trials Accelerates Understanding of Diseases (2014) (35)
Inflammation Following Traumatic Brain Injury in Humans: Insights from Data-Driven and Mechanistic Models into Survival and Death (2016) (34)
Therapeutic strategies in inflammasome mediated diseases of the liver. (2013) (34)
Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress. (2009) (34)
Augmenter of Liver Regeneration (ALR) Is a Novel Biomarker of Hepatocellular Stress/Inflammation: In Vitro, In Vivo and In Silico Studies (2012) (32)
From data patterns to mechanistic models in acute critical illness. (2014) (31)
Equation-based models of dynamic biological systems. (2008) (31)
Computational Insights on the Competing Effects of Nitric Oxide in Regulating Apoptosis (2008) (31)
NEUTROPHIL NAD(P)H OXIDASE IS REQUIRED FOR HEMORRHAGIC SHOCK-ENHANCED TLR2 UP-REGULATION IN ALVEOLAR MACROPHAGES IN RESPONSE TO LPS (2007) (31)
Predicting in vivo responses to biomaterials via combined in vitro and in silico analysis. (2015) (30)
Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis (2009) (30)
The effects of ingested mammalian blood factors on vector arthropod immunity and physiology. (2013) (30)
Intravascular radiation accelerates atherosclerotic lesion formation of hypercholesteremic rabbits. (2001) (30)
Mathematical modeling in necrotizing enterocolitis--a new look at an ongoing problem. (2007) (30)
Models of lower extremity damage in mice: time course of organ damage and immune response. (2011) (29)
Intestinal and hepatic expression of BNIP3 in necrotizing enterocolitis: regulation by nitric oxide and peroxynitrite. (2005) (29)
Solving Immunology? (2017) (29)
Sepsis: from pattern to mechanism and back. (2012) (29)
Global sensitivity analysis of a mathematical model of acute inflammation identifies nonlinear dependence of cumulative tissue damage on host interleukin-6 responses. (2014) (28)
Biosimulation of Inflammation and Healing in Surgically Injured Vocal Folds (2010) (28)
A Systems Engineering Perspective on Homeostasis and Disease (2013) (28)
Characterization of rat CD14 promoter and its regulation by transcription factors AP1 and Sp family proteins in hepatocytes. (2000) (28)
Pro- and Anti-Apoptotic Effects of Nitric Oxide in Irradiated Keratinocytes: The Role of Superoxide (2002) (27)
Chemically Modified Tetracycline 3 Prevents Acute Respiratory Distress Syndrome in a Porcine Model of Sepsis + Ischemia/Reperfusion–Induced Lung Injury (2012) (27)
Nitric oxide‐mediated inhibition of caspase‐dependent T lymphocyte proliferation (2003) (27)
Delayed Neutralization of Interleukin 6 Reduces Organ Injury, Selectively Suppresses Inflammatory Mediator, and Partially Normalizes Immune Dysfunction Following Trauma and Hemorrhagic Shock (2014) (27)
In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain (2015) (26)
Modeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis. (2013) (26)
Biosimulation of acute phonotrauma: An extended model (2011) (26)
Ionizing Radiation Potentiates the Induction of Nitric Oxide Synthase by Interferon‐γ and/or Lipopolysaccharide in Murine Macrophage Cell Lines: Role of Tumor Necrosis Factor‐α (2000) (26)
X Chromosome-Linked IRAK-1 Polymorphism Is a Strong Predictor of Multiple Organ Failure and Mortality Postinjury (2014) (26)
Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients (2016) (25)
Impact of chemically-modified tetracycline 3 on intertwined physiological, biochemical, and inflammatory networks in porcine sepsis/ARDS. (2015) (25)
Prospective Analyses of Cytokine Mediation of Sleep and Survival in the Context of Advanced Cancer (2018) (25)
Young and Aged Blunt Trauma Patients Display Major Differences in Circulating Inflammatory Mediator Profiles after Severe Injury. (2019) (25)
Evaluating Disorders with a Complex Genetics Basis. The Future Roles of Meta-analysis and Systems Biology (2005) (25)
Racial disparities and sex-based outcomes differences after severe injury. (2012) (24)
Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase. (2011) (24)
The early evolving sex hormone environment is associated with significant outcome and inflammatory response differences after injury (2015) (24)
An Exploratory Pathways Analysis of Temporal Changes Induced by Spinal Cord Injury in the Rat Bladder Wall: Insights on Remodeling and Inflammation (2009) (24)
Computational Modeling of Inflammation and Wound Healing. (2013) (24)
Catecholamines decrease nitric oxide production by cytokine-stimulated hepatocytes. (2001) (23)
Plasmodium development in the mosquito: biology bottlenecks and opportunities for mathematical modeling. (2008) (23)
A simple, rapid, and convenient Luminex™‐compatible method of tissue isolation (2008) (22)
Insights from Computational Modeling in Inflammation and Acute Rejection in Limb Transplantation (2014) (22)
A three-dimensional mathematical and computational model of necrotizing enterocolitis. (2013) (21)
A road map from single-cell transcriptome to patient classification for the immune response to trauma (2020) (21)
Til cell death do us part: nitric oxide and mechanisms of hepatotoxicity (2004) (21)
Computational Analysis Supports IL-17A as a Central Driver of Neutrophil Extracellular Trap–Mediated Injury in Liver Ischemia Reperfusion (2018) (21)
Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice (2013) (21)
Activation of latent transforming growth factor‐β1 by nitric oxide in macrophages: Role of soluble guanylate cyclase and MAP kinases (2009) (20)
Early Detection of Pressure Ulcer Development Following Traumatic Spinal Cord Injury Using Inflammatory Mediators. (2016) (20)
Transcriptomic response of murine liver to severe injury and hemorrhagic shock: a dual-platform microarray analysis. (2011) (20)
Cross-Talk Between Nitric Oxide and Transforming Growth Factor-β1 in Malaria (2004) (20)
Translational systems biology and voice pathophysiology (2010) (20)
Identification of distinct monocyte phenotypes and correlation with circulating cytokine profiles in acute response to spinal cord injury: a pilot study. (2014) (19)
Early Immunologic Response in Multiply Injured Patients With Orthopaedic Injuries Is Associated With Organ Dysfunction (2019) (19)
An Enrichment Strategy Yields Seven Novel Single Nucleotide Polymorphisms Associated With Mortality and Altered Th17 Responses Following Blunt Trauma (2017) (19)
Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries (2019) (19)
Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit (2020) (18)
One-dimensional elastic continuum model of enterocyte layer migration. (2007) (18)
A conceptual time window‐based model for the early stratification of trauma patients (2019) (18)
Agent‐based models of inflammation in translational systems biology: A decade later (2019) (17)
The effects of a tart cherry beverage on reducing exercise-induced muscle soreness (2017) (17)
One-Dimensional Elastic Continuum Model of Enterocyte Layer Migration (2007) (17)
Inflammation and Disease: Modelling and Modulation of the Inflammatory Response to Alleviate Critical Illness. (2018) (17)
Nitric oxide from the inducible nitric oxide synthase (iNOS) increases the expression of cytochrome P450 2E1 in iNOS-null hepatocytes in the absence of inflammatory stimuli. (2001) (17)
Hypoxia-Induced Overexpression of BNIP3 is Not Dependent on Hypoxia-Inducible Factor 1&agr; in Mouse Hepatocytes (2011) (16)
Cyclic AMP and Cyclic GMP suppress TNFα-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway (2006) (16)
Augmenting Surgery via Multi-scale Modeling and Translational Systems Biology in the Era of Precision Medicine: A Multidisciplinary Perspective (2016) (16)
A multiscale modeling approach to inflammation: A case study in human endotoxemia (2013) (16)
Computational modelling of the inflammatory response in trauma, sepsis and wound healing: implications for modelling resilience (2014) (16)
A Role for Angiotensin II in the Activation of Extracellular Signal-Regulated Kinases in the Liver During Hemorrhagic Shock (2003) (16)
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated? (2012) (16)
Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses (2021) (15)
Time for trauma immunology (2017) (14)
In vivo, in vitro, and in silico studies suggest a conserved immune module that regulates malaria parasite transmission from mammals to mosquitoes. (2013) (14)
Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice (2017) (14)
Mathematical Modeling of Early Cellular Innate and Adaptive Immune Responses to Ischemia/Reperfusion Injury and Solid Organ Allotransplantation (2015) (14)
HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen (2019) (14)
Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks (2016) (13)
Ionizing radiation potentiates the induction of nitric oxide synthase by interferon-gamma and/or lipopolysaccharide in murine macrophage cell lines. Role of tumor necrosis factor-alpha. (2000) (13)
Automated parameter estimation for biological models using Bayesian statistical model checking (2015) (13)
A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice (2018) (13)
Delayed re-endothelialization and T-cell infiltration following intracoronary radiation therapy in the porcine model. (2001) (13)
Mathematical and Statistical Modeling of Acute Inflammation (2004) (13)
Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury. (2019) (13)
Nitric Oxide and Ionizing Radiation Synergistically Promote Apoptosis and Growth Inhibition of Cancer by Activating p 53 (2004) (12)
Exercise Training Decreases Hepatic Injury and Metastases Through Changes in Immune Response to Liver Ischemia/Reperfusion in Mice (2020) (12)
Reduced hematopoietic function and enhanced radiosensitivity of transforming growth factor‐β1 transgenic mice (2000) (12)
Differential inflammatory networks distinguish responses to bone marrow-derived versus adipose-derived mesenchymal stem cell therapies in vascularized composite allotransplantation (2017) (11)
Hypoxia renders hepatocytes susceptible to cell death by nitric oxide. (2005) (11)
S-nitrosoglutathione reduces nonocclusive thrombosis rate following balloon overstretch injury and intracoronary irradiation of porcine coronary arteries. (2000) (11)
Low levels of mammalian TGF-beta1 are protective against malaria parasite infection, a paradox clarified in the mosquito host. (2008) (11)
Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness (2021) (11)
Unsupervised Clustering Analysis Based on MODS Severity Identifies Four Distinct Organ Dysfunction Patterns in Severely Injured Blunt Trauma Patients (2020) (11)
Laser Myocardial Revascularization Modulates Expression of Angiogenic, Neuronal, and Inflammatory Cytokines in a Porcine Model of Chronic Myocardial Ischemia (2001) (11)
Yttrium-90 delivered via a centering catheter and afterloader, given both before and after stent implantation, inhibits neointima formation in porcine coronary arteries. (2000) (11)
Hepatic Encephalopathy in Children With Acute Liver Failure: Utility of Serum Neuromarkers. (2019) (10)
Inflammatory Mediators Associated With Pressure Ulcer Development in Individuals With Pneumonia After Traumatic Spinal Cord Injury: A Pilot Study. (2017) (10)
68 – Biology of Nitric Oxide: Measurement, Modulation, and Models (2001) (10)
Cross-talk between nitric oxide and transforming growth factor-beta1 in malaria. (2004) (10)
Suppressed networks of inflammatory mediators characterize chronic venous insufficiency. (2018) (10)
BLOODFEEDING AS AN INTERFACE OF MAMMALIAN AND ARTHROPOD IMMUNITY (2008) (10)
Rationale and design of technology assisted stepped collaborative care intervention to improve patient-centered outcomes in hemodialysis patients (TĀCcare trial). (2018) (10)
Qualitative and quantitative analysis of DNA fragmentation using digital imaging. (1997) (10)
A putative “chemokine switch” that regulates systemic acute inflammation in humans (2021) (10)
Use of fluorescent microspheres to localize in vivo gene transfer injection sites. (2000) (10)
Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks (2021) (9)
TGFß and IL-10: inhibitory cytokines regulating immunity and the response to infection (2000) (9)
Analysis of the Plasma Metabolome after Trauma, Novel Circulating Sphingolipid Signatures, and In-Hospital Outcomes. (2021) (9)
URINE LEVELS OF SELECTED CHEMOKINES POSITIVELY CORRELATE WITH LOWER BLADDER CAPACITY AND PSYCHOMETRIC SCORES IN IC/PBS PATIENTS (2009) (9)
A Biohybrid Device for the Systemic Control of Acute Inflammation. (2012) (9)
Differential remodeling after balloon overstretch injury and either β- or γ-intracoronary radiation of porcine coronary arteries (2001) (9)
Computational Derivation of Core, Dynamic Human Blunt Trauma Inflammatory Endotypes (2021) (9)
The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure. (2017) (8)
Vascular repair after balloon overstretch injury in porcine model effects of intracoronary radiation. (2000) (8)
Normalization of nitric oxide flux improves physiological parameters of porcine kidneys maintained on pulsatile perfusion. (2003) (8)
Anti-restenotic effect of copper-62 liquid-filled balloon in porcine coronary arteries: novel use of a short half-life positron emitter. (2000) (8)
Thresholded area over the curve of spectrometric tissue oxygen saturation as an indicator of volume resuscitability in porcine hemorrhagic shock. (2007) (8)
Transforming growth factor-β in critical illness (2005) (8)
What Is Old Is New Again (2015) (8)
Intracoronary radiation therapy for prevention of restenosis. (1998) (8)
Elevations in Circulating sST2 Levels Are Associated With In-hospital Mortality and Adverse Clinical Outcomes After Blunt Trauma. (2019) (8)
IL-17A - A regulator in acute inflammation: Insights from in vitro, in vivo and in silico studies. (2018) (7)
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice. (1998) (7)
Induction of nitric oxide production in infiltrating leukocytes following in vivo irradiation of tumor-bearing mice. (1999) (7)
Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma (2019) (7)
Diagnosis and Management of Polytraumatized Patients With Severe Extremity Trauma. (2018) (7)
Dynamic Profiling: Modeling the Dynamics of Inflammation and Predicting Outcomes in Traumatic Brain Injury Patients (2016) (7)
Direct and indirect modulation of the inducible nitric oxide synthase by nitric oxide: feedback mechanisms in inflammation (2001) (7)
Persistence of Elevated Plasma CXCL8 Concentrations Following Red Blood Cell Transfusion in a Trauma Cohort (2012) (7)
Modeling and Hemofiltration Treatment of Acute Inflammation. (2016) (7)
Identification of Endotypes of Hospitalized COVID-19 Patients (2021) (6)
Bayesian inference of the lung alveolar spatial model for the identification of alveolar mechanics associated with acute respiratory distress syndrome (2013) (6)
Myocyte TLR4 enhances enteric and systemic inflammation driving late murine endotoxic ileus. (2015) (6)
From static to dynamic: a sepsis-specific dynamic model from clinical criteria in polytrauma patients. (2016) (6)
The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary liver cell loss in a three-dimensional perfusion bioreactor culture model developed for liver support. (2010) (6)
Identification of a Novel Pathway of Transforming Growth Factor-β1 Regulation by Extracellular NAD+ in Mouse Macrophages (2012) (6)
Mathematical Simulations of Sepsis and Trauma (2005) (6)
Integrating Data-Driven and Mechanistic Models of the Inflammatory Response in Sepsis and Trauma (2020) (6)
The Role of Nitric Oxide in Apoptosis and Autophagy: Biochemical and Computational Studies (2010) (6)
IRF3 Signaling within the Mouse Stroma Influences Sepsis Pathogenesis (2020) (6)
The use of multiplexing to identify cytokine and chemokine networks in the immune-inflammatory response to trauma. (2021) (5)
The independent prognostic value of global epigenetic alterations: An analysis of single-cell ATAC-seq of circulating leukocytes from trauma patients followed by validation in whole blood leukocyte transcriptomes across three etiologies of critical illness (2022) (5)
MPPED2 Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes (2019) (5)
Divergent COVID-19 Disease Trajectories Predicted by a DAMP-Centered Immune Network Model (2021) (5)
Innate immunity in disease: insights from mathematical modeling and analysis. (2014) (5)
An Aging-Related Single-Nucleotide Polymorphism is Associated with Altered Clinical Outcomes and Distinct Inflammatory Profiles in Aged Blunt Trauma Patients. (2020) (5)
Early Dynamic Orchestration of Immunologic Mediators Identifies Multiply Injured Patients who are Tolerant or Sensitive to Hemorrhage. (2020) (5)
Age-independent co-expression of antimicrobial gene clusters in the blood of septic patients. (2013) (5)
Adverse childhood experiences (ACEs), cell-mediated immunity, and survival in the context of cancer (2020) (5)
At the Interface between Acute and Chronic Inflammation: Insights from Computational Modeling (2012) (5)
Radioactive 133-Xenon Gas-filled Angioplasty Balloon: A Novel Intracoronary Radiation System to Prevent Restenosis (1998) (5)
Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress in vitro. (2019) (5)
Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis (2021) (4)
Parameter discovery for stochastic computational models in systems biology using Bayesian model checking (2014) (4)
Regulation of macrophage functions by macrophage deactivating factor, a tumor cell-derived cytokine (1992) (4)
Cyclic AMP and cyclic GMP suppress TNFalpha-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway. (2006) (4)
Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury (2020) (4)
The Impact of Stochasticity and Its Control on a Model of the Inflammatory Response (2018) (4)
Intracoronary Irradiation with 186/188Rhenium Following Balloon Overstretch Injury Reduces Neointima But Does Not Impair Vasoreactivity of Porcine Coronary Arteries (1999) (4)
Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling (2015) (4)
An Overview of the Translational Dilemma and the Need for Translational Systems Biology of Inflammation (2013) (4)
Decreased adventitial neovascularization after intracoronary irradiation in swine: a time course study. (2001) (4)
Transforming growth factor-beta in critical illness. (2005) (4)
Protective/reparative cytokines are suppressed at high injury severity in human trauma (2021) (4)
Yttrium-90 delivered via a centering catheter and remote afterloader, uniformly inhibits neointima formation after balloon injury or stenting in swine coronary arteries (1998) (4)
Optical Biopsy Using a Neural Network to Predict Gene Expression From Photos of Wounds (2022) (3)
“Thinking” vs. “Talking”: Differential Autocrine Inflammatory Networks in Isolated Primary Hepatic Stellate Cells and Hepatocytes under Hypoxic Stress (2017) (3)
Differential remodeling after balloon overstretch injury and either beta- or gamma-intracoronary radiation of porcine coronary arteries. (2001) (3)
Effect of CHRFAM7A Δ2bp gene variant on secondary inflammation after spinal cord injury (2021) (3)
Modeling Host–Vector–Pathogen Immuno-inflammatory Interactions in Malaria (2013) (3)
Integrating Mindsets and Toolsets at the Frontier of Systems Biology (2021) (3)
Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure (2021) (3)
Agent-based simulation of urinary tract infection leading to renal scarring (2007) (3)
DIFFERENTIAL ACTIVATION OF RECOMBINANT HUMAN LATENT TRANSFORMING GROWTH FACTOR-β1 (TGF-β1) BY ACID AND HEAT (2007) (3)
Radioactive 133-Xenon Gas-Filled Balloon to Prevent Restenosis: Dosimetry, Efficacy, and Safety Considerations (2002) (3)
The next generation of collaborative care: The design of a novel web-based stepped collaborative care intervention delivered via telemedicine for people diagnosed with cancer. (2021) (3)
Optimizing a therapeutic intervention: systems engineering of a pheresis intervention for sepsis (2006) (3)
Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling (2022) (3)
An agent-based model of acute phonotrauma (2005) (2)
IN SILICO AND IN VIVO STUDIES MODELING THE AGED ACUTE INFLAMMATORY RESPONSE (2006) (2)
Endothelial Biomedicine: Equation-Based Models of Dynamic Biological Systems (2007) (2)
A Roadmap for a Rational Future (2015) (2)
Interleukin-17 as a spatiotemporal bridge from acute to chronic inflammation: Novel insights from computational modeling. (2023) (2)
Oxidase Activation in Neutrophils: Role of Hemorrhagic Shock Induces NAD(P)H (2013) (2)
Agent-Based Modeling of Wound Healing: Examples for Basic and Translational Research (2020) (2)
Delayed healing and increased thrombosis following intracoronary radiation in balloon injured porcine coronary arteries. (1999) (2)
URINE LEVELS OF INFLAMMATORY CHEMOKINES CAN BE NOVEL BIOMARKERS FOR THE OVERACTIVE BLADDER (2009) (2)
Modulation of protein expression and activity by radiation: relevance to intracoronary radiation for the prevention of restenosis. (1999) (2)
Depression and health care utilization and costs in patients diagnosed with cancer. (2019) (2)
Dynamic Data-Driven Modeling for Ex Vivo Data Analysis: Insights into Liver Transplantation and Pathobiology (2017) (2)
Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine (2021) (2)
depression and Increased Risk of Mortality in Cancer: The Underlying Biological Mechanisms Remain Elusive : 15-5 (2016) (2)
Mathematical models predict the course of the inflammatory response in rats subjected to trauma-hemorrhagic shock and to anti–tumor necrosis factor α therapy in endotoxemia (2005) (2)
Systems biology applied to wound healing (2010) (2)
A linear code parameter search algorithm with applications to immunology (2009) (2)
Early prediction of length of intensive care unit stay from inflammatory mediators in trauma patients (2011) (2)
Gene network analysis of liver allografts preserved with machine perfusion (649.10) (2014) (2)
Parameter estimation and synthesis for systems biology: New algorithms for nonlinear and stochastic models (2011) (2)
Predicting Experimental Sepsis Survival with a Mathematical Model of Acute Inflammation (2021) (2)
ANALYSIS OF GENETIC AND PROTEOMIC FACTORS OF THE IMMUNE RESPONSE MEDIATING CELLULAR INFILTRATION AND TRAFFICKING IN SKIN REJECTION OF COMPOSITE TISSUE ALLOGRAFTS: 3038 (2010) (2)
Low-energy X-radiation for prevention of restenosis results in localized inhibition of V79 fibroblast cell proliferation. (1998) (1)
Histological demonstration of coronary dissection leading to double luminal artery in swine model. (2001) (1)
Machine learning and mechanistic computational modeling of inflammation as tools for designing immunomodulatory biomaterials (2021) (1)
Efficacy of a stepped collaborative care intervention for comorbid cancer and depression: Health care utilization and costs. (2019) (1)
Agent-based simulation of acute phonotrauma in cases with various cytokine profiles (2006) (1)
Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill (2022) (1)
Agent-Based Models of Wound Healing (2013) (1)
Interesting Times: The Translational Dilemma and the Need for Translational Systems Biology of Inflammation (2015) (1)
Mathematical modeling of community-acquired pneumonia patients (2009) (1)
250: INDIVIDUAL-SPECIFIC PRINCIPAL COMPONENT ANALYSIS PREDICTS EARLY ORGAN DYSFUNCTION IN TRAUMA PATIENTS (2013) (1)
Predicting the response to therapy from a mathematical model (2004) (1)
Supplemental oxygen does not synergize with intracoronary radiation for the prevention of restenosis in porcine coronary arteries. (1999) (1)
An adaptive, negative feedback circuit in a biohybrid device reprograms dynamic networks of systemic inflammation in vivo (2023) (1)
Automated parameter estimation for biological models using Bayesian statistical model checking (2015) (1)
PREDICTING THE ACUTE INFLAMMATORY RESPONSE IN COMBINED TRAUMA‐HEMORRHAGE AND ENDOTOXEMIA USING MATHEMATICAL SIMULATIONS: 146 (2004) (1)
The Effects of Tacrolimus on Tissue-Specific, Protein-Level Inflammatory Networks in Vascularized Composite Allotransplantation (2021) (1)
Reverse Engineering the Inflammatory "Clock": From Computational Modeling to Rational Resetting. (2016) (1)
A simple mathematical model of lipopolysaccharide signaling through toll-like receptor 4 results in complex insights on preconditioning (2007) (1)
Capturing scenarios of repeated endotoxin administrations in a small mathematical model of the acute inflammatory response and mathematically exploring the nature of tolerance (2005) (1)
Quality Control Measures and Validation in Gene Association Studies: Lessons for Acute Illness. (2020) (1)
Using nonlinear model predictive control to optimize inflammation-modulating therapy (2007) (1)
Plasma cytokine levels in experimental necrotizing enterocolitis: a mathematical model is needed (2005) (1)
Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss. (2022) (1)
CONTINUOUS SUBLINGUAL PCO2 AS A RAPID INDICATOR OF CHANGES IN TISSUE PERFUSION IN HEMORRHAGIC SHOCK: AN EXPERIMENTAL STUDY (2006) (1)
Cytoprotective Effects of NO against Oxidative Injury (2002) (1)
Baseline Plasma Inflammatory Profile Is Associated With Response to Neoadjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma (2021) (1)
Surface Profile of the Internal Elastic Lamina May Modulate Thrombosis Following Intracoronary Radiation in Balloon‐Injured Porcine Arteries (1999) (1)
Prediction of the Acute Inflammatory Response From A Mathematical Mode (2003) (1)
Trauma/hemorrhage-induced inflammation in mice: Insights from data-driven models (2011) (1)
A ROLE FOR ANGIOTENSIN II IN THE EARLY ACTIVATION OF MAP KINASE IN HEMORRHAGIC SHOCK: 42 (2001) (1)
CD8+ T Cell Transcriptional Profiles of Pediatric Heart Transplant Recipients That Carry EBV Loads in Peripheral Blood. (2014) (1)
From Data to Knowledge in Translational Systems Biology: An Overview of Computational Approaches Across the Scientific Cycle (2015) (1)
Generating synthetic data with a mechanism-based Critical Illness Digital Twin: Demonstration for Post Traumatic Acute Respiratory Distress Syndrome (2023) (1)
International Journal of Burns and Trauma: Editorial Board (2012) e-Century Publishing Corporation. (2012) (0)
Transgene is tightly regulated by Geneswitch system in 293 cells (2007) (0)
Principal component analysis delineates both subgroup- and patient-specific insights into acute inflammation in trauma patients (2009) (0)
Interim analyses of the efficacy of a collaborative care intervention for patients diagnosed with comorbid cancer and depression. (2019) (0)
Agent-Based Modeling and Translational Systems Biology: An Evolution in Parallel (2015) (0)
1064: MATHEMATICAL MODELING OF ALTERED INFLAMMATORY RESPONSE AFTER TRAUMATIC SPINAL CORD INJURY IN BLUNT TRAUMA (2012) (0)
A GENE ONTOLOGY AND NETWORK-BASED ANALYSIS OF MURINE LIVER IN TRAUMATIC-HEMORRHAGIC SHOCK (2006) (0)
Toward a model-driven design of clinical trials and individualized therapies (2005) (0)
Dynamic Hypergraphs: A novel analysis pipeline for defining spatiotemporal inflammation networks (2023) (0)
63: Post-traumatic bacterial translocation (BT) is toll-like receptor 4 (TLR4) dependent but does not drive the inflammatory response (2007) (0)
Identifying candidate model clouds in large parameter spaces (2005) (0)
Biomedical Research Since the Molecular Revolution: An Embarrassment of Riches (2015) (0)
Oscillations of NO synthase in the midgut of the Anopheles mosquito (2007) (0)
Augmenting Surgery via Multi-scale Modeling and Translational Systems Biology in the Era of Precision Medicine: A Multidisciplinary Perspective (2016) (0)
Infrared Thermography Confirms Inflammatory Differences in Refluxing Versus Competent Lower Extremity Veins (2020) (0)
OP25: A COMPUTATIONAL MODEL TO PROFILE CYTOKINE NETWORKS MEDIATING ACUTE REJECTION AFTER COMPOSITE TISSUE ALLOTRANSPLANTATION (2009) (0)
Genome-Wide Analysis Suggests a Differential Interaction between Genetic Polymorphism and Injury Severity in Driving Outcomes Post-Injury (2022) (0)
PLASMINOGEN ACTIVATOR INHIBITOR‐1 (PAI‐1) CONTRIBUTES TO HEPATIC INJURY DURING HEMORRHAGIC SHOCK: 133 (2004) (0)
An Overview of the Translational Dilemma and the Need for Model-Based Precision Medicine (2020) (0)
A Brief History of the Philosophical Basis of the Scientific Endeavor: How We Know What We Know, and How to Know More (2015) (0)
NAD+ IMPROVES SURVIVAL OF ENDOTOXEMIC MICE.: 225 (2004) (0)
Central role of danger signals in sepsis, trauma, and hemorrhage: insights from mathematical simulations (2005) (0)
Dynamic Knowledge Representation and the Power of Model Making (2015) (0)
A temporal analysis of the hepatic transcriptomic response to bone fracture and hemorrhagic shock in mice (2007) (0)
A Systemic Storm in Critically Injured Humans Revealed by Longitudinal Multi-Omics (2021) (0)
Upregulation of IL-1 and Caspase-1 in experimental necrotizing enterocolitis (NEC) (2008) (0)
HEPATIC INJURY AND SYSTEMIC INFLAMMATION AFTER TRAUMA REQUIRES TLR4 AND IS MEDIATED BY HMGB1 (2006) (0)
Insights from the creation of a conceptual model of natural killer and NKT cell responses during acute inflammation (2006) (0)
Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients (2022) (0)
Modeling and Hemoﬁltration Treatment of Acute Inﬂammation † (2016) (0)
EXPRESSION OF THE BCL‐2 BINDING PROTEIN BNIP3 IN A MODEL OF NECROTIZING ENTEROCOLITIS.: 243 (2004) (0)
Very low frequency variability in the peripheral circulation: the possibility of plethysmographic quantification. (2009) (0)
Transcriptomic response of murine liver to severe injury and hemorrhagic shock: A dual platform microarray analysis (2009) (0)
Human Nature, Politics, and Translational Inertia (2015) (0)
A multiscale, agent-based model of liver inflammation, cirrhosis, and cancer (2012) (0)
IN SILICO CLINICAL TRIALS: A METHOD COMING OF AGE: 393 (2004) (0)
Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks (2021) (0)
Temporal Transcriptomic Response of Murine Liver to Trauma and Hemorrhagic Shock: A Dual Platform Microarray Analysis (2010) (0)
Chapter 2.5 – Complexity in Biomedical Research: Mysticism Versus Methods (2015) (0)
Systemic inflammation and liver dysfunction after trauma is Toll-like receptor 4 (TLR-4) dependent (2006) (0)
Data-driven segregation of trauma patients using principal component analysis yields novel, patient-specific insights into acute inflammation (2011) (0)
Early detection of pressure ulcer development following traumatic spinal cord injury using inflammatory mediator concentrations (2015) (0)
Does the use of a cytokine 'filter' during cardiopulmonary bypass make sense? (2004) (0)
PLASMINOGEN ACTIVATOR INHIBITOR‐1 (PAI‐1) IS REGULATED BY iNOS DURING HEMORRHAGIC SHOCK AND IS INVOLVED IN PRO‐INFLAMMATORY SIGNALING AND TISSUE INJURY.: 150 (2003) (0)
Optical Biopsy using a neural network to predict functional state from photos of wounds (2022) (0)
Agent-based model of lung inflammation (2008) (0)
CHEMOKINE NETWORKS CHARACTERIZE THE INFLAMMATORY RESPONSE OF SEVERE EXTREMITY-INJURED TRAUMA PATIENTS (2016) (0)
In Silico Trials and Personalized Therapy for Sepsis and Trauma (2020) (0)
Author index and subject index (1976) (0)
Toward Computational Identification of Multiscale “Tipping Points” in Acute Inflammation and Multiple Organ Failure (2012) (0)
MATHEMATICAL SIMULATION OF POST‐HEMORRHAGE ENDOTOXEMIA: TIMING IS CRITICAL FOR SURVIVAL.: 124 (2003) (0)
Induction of IDO Dendritic Cells via STAT3-Dependent Allostimulatory Function of Liver Myeloid Hepatic Stellate Cells Undermine the (2012) (0)
Nitric oxide: at the heart of the matter (2001) (0)
Editorial International Journal of Burns and Trauma Editorial Board (2012) (0)
Inflammatory signals and network connections implicate cell-mediated immunity in chronic venous insufficiency (2021) (0)
EP03.01-014 Results From the BEWELL Study: Black Raspberry Nectar for the Prevention of Lung Cancer (NCT04267874) (2022) (0)
IN VIVO EXPOSURE TO LPS DESENSITIZES HEPATOCYTES TO SUBSEQUENT STIMULATION WITH BACTERIAL PRODUCTS: ROLE OF TLR4: 170 (2001) (0)
Severely Injured Trauma Patients with High Circulating IL-15 Levels Display Worse Outcomes and Distinct Inflammatory Profiles, Suggesting a Role for Natural Killer Cell Activation (2019) (0)
Survival in Immunocompetent Recipients Synergize To Promote Long-Term Graft and Alloantigen-Specific Regulatory T Cells Mammalian Target of Rapamycin Inhibition (2009) (0)
Induction and activation of macrophage transforming growth factor-β1 by extracellular nicotinamide adenine dinucleotide (NAD+) and its metabolite, cyclic ADP ribose: In vitro and in silico studies (2012) (0)
Computational simulation of individual inflammation and outcomes in trauma patients (2008) (0)
Mathematical model of necrotizing enterocolitis: effects of probiotic treatment and Toll-like receptor 4 inhibition (2010) (0)
Modeling damage in irreversible hemorrhagic shock (2005) (0)
Primary Chronic Venous Insufficiency Is Distinguished by Attenuated Circulating Inflammatory Mediators and Healing Networks (2019) (0)
Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE STUDY). (2022) (0)
Stress as a predictor of tumor growth and development of metastases. (2021) (0)
A parallel implementation of an agent-based modeling platform with application in modeling calcium releases in cardiomyocytes (2009) (0)
QS402. IL-6 Synergizes With T Helper II Cytokines to Up-Regulate Arginase I in Spleen Myeloid Suppressor Cells Following Traumatic Stress (2008) (0)
of hepatic injury after trauma-hemorrhagic shock Insights into the role of interleukin-6 in the induction (2015) (0)
THE RAPID UPREGULATION OF EARLY GROWTH RESPONSE‐1 (EGR‐1) IN HEMORRHAGIC SHOCK REGULATES INFLAMMATION IN THE LIVER: 163 (2004) (0)
Quantifying the size and healing of volumetric muscle wounds using 3D Slicer on CT scans in a canine model (2021) (0)
Integrated oral session 1: Wed 2/7 1:00 pmTrauma/critical care I: Injury and immunity66: Systemic inflammation and end organ injury after peripheral tissue injury requires functional TLR4 on bone marrow-derived cells (2007) (0)
MetfOrmin BenefIts Lower Extremities with Intermittent Claudication (MOBILE IC): randomized clinical trial protocol (2023) (0)
Integrative “omic” analysis of organ-wide coregulation patterns highlights pathogen-dependent activation of 25-hydroxycholesterol during septic disease progression (2013) (0)
IL-6 and IL-1{alpha} together, but not alone, are key modulators of regulatory T cell suppressive function: insights from computational and in vitro studies. (2010) (0)
24: A COMPUTATIONAL MODEL TO PROFILE CYTOKINE NETWORKS MEDIATING ACUTE REJECTION AFTER COMPOSITE TISSUE ALLOTRANSPLANTATION (2010) (0)
Respiratory and Neuro-Inflammatory Control Networks in a Rat Model of E. Coli Peritonitis (2020) (0)
Distinctive Immune Signaling Patterns and Factors in Rat Skin Rejection after Transplant: 2303 (2012) (0)
Launching of international journal of burns and trauma. (2011) (0)
Data-Driven and Statistical Models (2015) (0)
From mice to rats: interspecies prediction of the systemic inflammatory response using mathematical simulations (2006) (0)
What's New in Shock, June 2018? (2018) (0)
Data-Driven Modeling of Liver Injury, Inflammation, and Fibrosis (2020) (0)
Mechanistic Modeling of Critical Illness Using Equations (2015) (0)
The Rationale and Implementation of Model-Based Precision Medicine for Inflammatory Diseases (2020) (0)
PCO2 as surrogate for mathematically-modeled tissue dysfunction/damage during a nonlethal hemorrhagic shock model in mice (2006) (0)
A computational analysis of dynamic, multiorgan inflammation induced by endotoxin in mice (2017) (0)
TLR4 MEDIATES HEMORRHAGIC SHOCK-INDUCED NADPH OXIDASE ACTIVATION IN NEUTROPHIL (2006) (0)
2 Reduced Model of Acute Inflammation (2008) (0)
COMBINED IN SILICO AND IN VIVO STUDIES ON ACUTE INFLAMMATION (2006) (0)
Mathematical model of SARS-CoV-2 immunity predicts Paxlovid rebound (2023) (0)
Elevations in Circulating sST2 Levels are Associated with In-hospital Mortality and Adverse Clinical Outcomes following Blunt Trauma (2019) (0)
Agent-based simulation of bacterial sepsis: a teaching tool for science students (2007) (0)
Computational model of NOS/TGF-Beta1/Plasmodia system in humans and mosquitoes (2007) (0)
and Implications for Allograft Tolerance Cells by Hepatic Stellate Cells: Role of Endotoxin Selective Expansion of Allogeneic Regulatory T (2012) (0)
Data-driven modeling approaches for predicting outcomes following traumatic brain injury (2009) (0)
Cytokines as Early Predictors of Allograft Rejection.: Abstract# D2812 (2014) (0)
Using a mathematical model to predict and test adverse drug response in septic patients (2005) (0)
Patient-specific mathematical models of traumatic brain injury (2009) (0)
The Rationale and Implementation of Translational Systems Biology as a New Paradigm for the Study of Inflammation (2013) (0)
Endothelial Specificity of ICAM2, Flt-1, and Tie2 Promoters In Vitro and In Vivo (2007) (0)
Randomized Clinical Trials: A Bridge Too Far? (2015) (0)
Review Article Computational and systems biology in trauma and sepsis: current state and future perspectives (2012) (0)
Global sensitivity analysis of endotoxin-induced acute inflammatory responses predicts the multimodal dependence of global tissue damage both on host IL-6 responses and endotoxin dose (2013) (0)
Towards Translational Systems Biology of Inflammation (2015) (0)
Abstract 2060: A Novel Hemorrhagic Shock Model To Study Compensatory Mechanisms and Circulatory Collapse (2008) (0)
Porcine endotoxemia: Multiplexed cytokine analysis and mathematical modeling (2009) (0)
Lipidomic signatures align with inflammatory patterns and outcomes in critical illness (2022) (0)
Tissue-specific patterns of caspase-1 and cytokines in excisional wounds are altered by shock in rat skin and muscle (2013) (0)
ToleranceEndotoxin and Implications for Allograft T Cells by Hepatic Stellate Cells: Role of Selective Expansion of Allogeneic Regulatory (2012) (0)
A stochastic analysis of the inflammatory response (2012) (0)
QS385. Temporal Transcriptomic Response of Murine Liver to Severe Injury and Hemorrhagic Shock (2009) (0)
IL-6 and IL-1α together, but not alone, are key modulators of regulatory T cell suppressive function: insights from computational and in vitro studies. (49.11) (2010) (0)
Towards an improved extracorporeal liver support device: Nitric oxide (NO) inhibits apoptotic liver cell death in a four compartment bioreactor culture model (2006) (0)
Abstract 102: Inflammatory Mediators Modulate Alloreactive T Cell Susceptibility to Immune-Regulation in Reconstructive Transplantation (2014) (0)
HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen (2019) (0)
Biomarkers Associated with Pressure Ulcer Formation in Traumatic Spinal Cord Individuals with Pneumonia (2016) (0)
Combined network and mathematical modeling suggests novel inflammation positive feedback circuit and role for IL-1α in experimental trauma/hemorrhage and hepatocyte hypoxia (2013) (0)
VALIDATION AND CALIBRATION IN ANIMALS OF A MATHEMATICAL MODEL OF ACUTE INFLAMMATION: 392 (2004) (0)
Complexity in Biomedical Research (2015) (0)
ModelsofLowerExtremityDamageinMice:TimeCourseofOrganDamage and Immune Response (2011) (0)
Towards systems immunology of critical illness at scale: from single cell 'omics to digital twins. (2023) (0)
TLR4-competent hematopoietic cells are required for systemic inflammation and hepatic injury after trauma/hemorrhage (2006) (0)
Central role for neurally dysregulated IL-17A in dynamic networks of systemic and local inflammation in combat casualties (2023) (0)
LONGITUDINAL ANALYSIS OF TRANSCRIPTOMIC SUBTYPES IN TRAUMA PATIENTS (2022) (0)
TWO AUTOCOVARIANCE-BASED MEASURES OF BALANCE IN PARKINSONIANS AND NORMAL CONTROLS. (2010) (0)
Radioactive 32P-stent for in-stent restenosis in the porcine model. (1999) (0)
ALLOGENEIC AND SYNGENEIC CYTOKINE NETWORKS IN SKIN MUSCLE AND COMPOSITE TISSUE ALLOGRAFTS: 2987 (2010) (0)
SOCS1 CONTRIBUTES TO LPS DESENSITIZATION IN MOUSE HEPATOCYTES.: 108 (2004) (0)
A thermodynamic tolerance assessment of single nucleotide polymorphisms relevant to acute inflammation and coagulation (2007) (0)
A Brief History of Biomedical Research up to the Molecular Biology Revolution (2015) (0)
P172 Combined computational and experimental analyses of IL-6 and IL-1 reveal distinct mechanisms of action in the modulation of regulatory T cell suppressive activity (2012) (0)
Getting Science to Scale: Accelerating the Development of Translational Computational Models (2015) (0)
Non-vascular myocyte TLR4 regulates intestinal and systemic inflammation and prevents late ileus in murine endotoxemia (2012) (0)
Predicting evolution of critically ill patients Jan Ramon (0)
Dynamic Bayesian Network Analysis of Inflammation Biomarkers Reveals Age-Related Changes of the Inflammatory Response after Trauma (2018) (0)
Early growth response-1 (EGR-1) expression in the liver in hemorrhagic shock (HS) is localized to hepatocytes and upregulated by hypoxia or reactive oxygen species (ROS) exposure in vitro (2004) (0)

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What Schools Are Affiliated With Yoram Vodovotz?

Yoram Vodovotz is affiliated with the following schools:

Cornell University
University of Pittsburgh

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What Schools Are Affiliated With Yoram Vodovotz?

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