Yoshiaki Ito
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Researcher ORCID ID = 0000-0002-9037-1184
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Computer Science
Yoshiaki Ito's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Yoshiaki Ito's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer (2002) (1064)
- Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development (2002) (763)
- TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins (2000) (680)
- Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. (2004) (565)
- A Role for Hematopoietic Stem Cells in Promoting Angiogenesis (2000) (528)
- MicroRNA-140 plays dual roles in both cartilage development and homeostasis. (2010) (526)
- Interaction and Functional Cooperation of PEBP2/CBF with Smads (1999) (468)
- Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α (1993) (467)
- Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer (1999) (415)
- Tyrosine phosphorylation controls Runx2‐mediated subnuclear targeting of YAP to repress transcription (2004) (379)
- In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis. (2002) (365)
- Oncogenic potential of the RUNX gene family: ‘Overview’ (2004) (345)
- Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons (2002) (320)
- The RUNX family: developmental regulators in cancer (2015) (313)
- Dimerization with PEBP2β protects RUNX1/AML1 from ubiquitin–proteasome‐mediated degradation (2001) (299)
- RUNX transcription factors as key targets of TGF-β superfamily signaling (2003) (289)
- Transcriptional regulation of osteopontin gene in vivo by PEBP2αA/CBFA1 and ETS1 in the skeletal tissues (1998) (278)
- Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation (2002) (257)
- Heterozygous PU.1 mutations are associated with acute myeloid leukemia. (2002) (255)
- Mutual activation of Ets‐1 and AML1 DNA binding by direct interaction of their autoinhibitory domains (1999) (246)
- The Mohawk homeobox gene is a critical regulator of tendon differentiation (2010) (246)
- RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis. (2008) (218)
- Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit (1998) (210)
- RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes. (2008) (207)
- Molecular basis of tissue‐specific gene expression mediated by the Runt domain transcription factor PEBP2/CBF (1999) (202)
- RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. (2006) (199)
- Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation*S⃞ (2008) (190)
- RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. (2005) (183)
- RUNX family: Regulation and diversification of roles through interacting proteins (2013) (182)
- RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21WAF1/Cip1 Expression in Cooperation with Transforming Growth Factor β-Activated SMAD (2005) (181)
- MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer. (2010) (175)
- The RUNX3 Tumor Suppressor Upregulates Bim in GastricEpithelial Cells Undergoing Transforming Growth Factorβ-Induced Apoptosis (2006) (170)
- Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain (1995) (162)
- RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. (2005) (161)
- RUNX transcription factors as key targets of TGF-beta superfamily signaling. (2003) (158)
- Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription (2005) (153)
- Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations. (2002) (153)
- Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3. (2007) (147)
- RUNX3 Cooperates with FoxO3a to Induce Apoptosis in Gastric Cancer Cells* (2006) (144)
- A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. (2009) (138)
- AML1(−/−) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene (1998) (138)
- Nomenclature for Runt-related (RUNX) proteins (2004) (135)
- Integrative analysis of RUNX1 downstream pathways and target genes (2008) (129)
- Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer. (2004) (129)
- High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis (2018) (116)
- Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice. (2017) (108)
- Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain (2000) (106)
- Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms (2002) (105)
- Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma. (2013) (105)
- SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. (2002) (104)
- CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer (2007) (104)
- Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity* (1996) (102)
- MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma* (2013) (102)
- Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. (2007) (102)
- CBFa(AML/PEBP2)‐related elements in the TGF‐β type I receptor promoter and expression with osteoblast differentiation (1998) (98)
- The Corepressor mSin3A Regulates Phosphorylation-Induced Activation, Intranuclear Location, and Stability of AML1 (2004) (98)
- K‐Ras mediates cytokine‐induced formation of E‐cadherin‐based adherens junctions during liver development (2002) (92)
- Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis (2010) (92)
- Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells. (2010) (91)
- Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor (2002) (91)
- Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer (2005) (89)
- RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression (2008) (89)
- RUNX3, A Novel Tumor Suppressor, Is Frequently Inactivated in Gastric Cancer by Protein Mislocalization (2005) (89)
- Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult (2007) (87)
- Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo (2015) (87)
- Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. (2005) (87)
- A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells (2010) (85)
- Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects. (2014) (85)
- Runt Domain Factor (Runx)-dependent Effects on CCAAT/ Enhancer-binding Protein δ Expression and Activity in Osteoblasts* (2000) (83)
- Frequent Loss of RUNX3 Expression by Promoter Hypermethylation in Gastric Carcinoma (2004) (81)
- Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis (2016) (78)
- Runx transcription factors in neuronal development (2008) (78)
- Loss of Runx3 is a key event in inducing precancerous state of the stomach. (2011) (77)
- Runx3 Protects Gastric Epithelial Cells Against Epithelial‐Mesenchymal Transition‐Induced Cellular Plasticity and Tumorigenicity (2012) (77)
- Requirement for Runx Proteins in IgA Class Switching Acting Downstream of TGF-β1 and Retinoic Acid Signaling (2010) (77)
- Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response. (2015) (75)
- Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines (2003) (74)
- Runx1 is involved in primitive erythropoiesis in the mouse. (2008) (73)
- Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility (2010) (73)
- Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation (1998) (70)
- Diminution of the AML1 Transcription Factor Function Causes Differential Effects on the Fates of CD4 and CD8 Single-Positive T Cells1 (2000) (70)
- Three species of polyoma virus tumor antigens share common peptides probably near the amino termini of the proteins (1978) (70)
- RUNX3 Modulates DNA Damage-mediated Phosphorylation of Tumor Suppressor p53 at Ser-15 and Acts as a Co-activator for p53* (2010) (69)
- Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs (2016) (69)
- RUNX3 functions as an oncogene in ovarian cancer. (2011) (68)
- PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis. (2008) (67)
- Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity (2006) (66)
- Untransformed rat cells containing free and integrated dna of a polyoma nontransforming (Hr-t) mutant (1979) (66)
- Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run, in Caenorhabditis elegans (2002) (65)
- Runx3-/- gastric epithelial cells differentiate into intestinal type cells. (2004) (62)
- EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway (2013) (60)
- The Transcription Factor Runx3 Represses the Neurotrophin Receptor TrkB during Lineage Commitment of Dorsal Root Ganglion Neurons* (2007) (59)
- Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination. (2009) (57)
- Characterization of GATA‐1+ hemangioblastic cells in the mouse embryo (2006) (56)
- Dynamic regulation of the expression of neurotrophin receptors by Runx3 (2008) (55)
- RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer (2018) (54)
- Wwp2 maintains cartilage homeostasis through regulation of Adamts5 (2019) (54)
- Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3 (2005) (54)
- Src Kinase Phosphorylates RUNX3 at Tyrosine Residues and Localizes the Protein in the Cytoplasm* (2010) (53)
- The RUNX complex: reaching beyond haematopoiesis into immunity (2015) (51)
- Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and ras pathways during hepatic development (2000) (51)
- Smad2 Overexpression Enhances Smad4 Gene Expression and Suppresses CBFA1 Gene Expression in Osteoblastic Osteosarcoma ROS17/2.8 Cells and Primary Rat Calvaria Cells* (1998) (50)
- Quantitative analysis of tumor-derived methylated RUNX3 sequences in the serum of gastric cancer patients. (2009) (49)
- Prostaglandin F2α activates phospholipase D independently from activation of protein kinase C in osteoblast‐like cells (1994) (49)
- PEBP2αA/CBFA1 mutations in Japanese cleidocranial dysplasia patients (2000) (47)
- Differential Expression of Subspecies of Polyomavirus and Murine Leukemia Virus Enhancer Core Binding Protein, PEBP2, in Various Hematopoietic Cells (1992) (46)
- Functional analysis of RUNX2 mutations in cleidocranial dysplasia: novel insights into genotype-phenotype correlations. (2003) (46)
- Targets of genome copy number reduction in primary breast cancers identified by integrative genomics (2007) (45)
- The Runt Domain Transcription Factor, PEBP2/CBF, and its Involvement in Human Leukemia (1997) (45)
- Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice (2005) (45)
- Putative intermediate precursor between hematogenic endothelial cells and blood cells in the developing embryo (2003) (44)
- Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes (2009) (44)
- Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice (2005) (44)
- Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2 (1999) (43)
- The Capacity of Polyomavirus Enhancer Binding Protein 2αB (AML1/Cbfa2) To Stimulate Polyomavirus DNA Replication Is Related to Its Affinity for the Nuclear Matrix (1998) (43)
- RUNX3 Inactivation in Colorectal Polyps Arising Through Different Pathways of Colonic Carcinogenesis (2009) (42)
- The cDNA cloning of the transcripts of human PEBP2αA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia (1997) (41)
- Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1. (2010) (41)
- Intimate Relationship Between TGF-&bgr;/BMP Signaling and Runt Domain Transcription Factor, PEBP2/CBF (2001) (41)
- Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis. (2006) (40)
- Runx1: no longer just for leukemia (2012) (39)
- Targeted Gene Deletion of miRNAs in Mice by TALEN System (2013) (39)
- Detection of p53 Gene Mutations in Human Ovarian and Endometrial Cancers by Polymerase Chain Reaction‐Single Strand Conformation Polymorphism Analysis (1992) (39)
- Identification of targets of tumor suppressor microRNA-34a using a reporter library system (2016) (38)
- Role of RUNX3 in bone morphogenetic protein signaling in colorectal cancer. (2010) (38)
- The protooncogene product, PEBP2β/CBFβ, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures (1997) (37)
- Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. (2021) (36)
- RAS oncogenic signal upregulates EZH2 in pancreatic cancer. (2012) (36)
- Synergy of PEBP2/CBF with mi transcription factor (MITF) for transactivation of mouse mast cell protease 6 gene (1999) (36)
- Runx3 is essential for the target-specific axon pathfinding of trkc-expressing dorsal root ganglion neurons. (2003) (35)
- CD133 is a marker of gland‐forming cells in gastric tumors and Sox17 is involved in its regulation (2011) (35)
- A factor discriminating between the wildtype and a mutant polyomavirus enhancer (1987) (35)
- Molecular insights into PEBP2/CBFβ-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBFβ (1999) (34)
- Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer (2012) (34)
- Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon (2016) (34)
- RUNX3 Attenuates β-Catenin/T Cell Factors in Intestinal Tumorigenesis (2009) (33)
- Increased dosage of the RUNX1/AML1 gene: a third mode of RUNX leukemia? (2005) (32)
- Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera. (2004) (32)
- Runx3 deficiency results in myeloproliferative disorder in aged mice. (2013) (31)
- RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker. (2010) (31)
- Runx1 is involved in the fusion of the primary and the secondary palatal shelves. (2009) (31)
- Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment. (2007) (30)
- Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells (2014) (30)
- RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. (2018) (27)
- Positive and negative regulation of chondrogenesis by splice variants of PEBP2αA/CBFα1 in clonal mouse EC cells, ATDC5 (1999) (27)
- Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation. (2013) (27)
- PEBP 2 / PEA 2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AMLI gene (2005) (27)
- RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point (2018) (25)
- TGFβ Promotes Genomic Instability after Loss of RUNX3. (2018) (25)
- Runt domains take the lead in hematopoiesis and osteogenesis (1999) (25)
- cDNA cloning of Runx family genes from the pufferfish (Fugu rubripes). (2007) (24)
- Heterozygous PU.1 mutations are associated with acute myeloid leukemia. (2002) (24)
- Analyses of promoter hypermethylation for RUNX3 and other tumor suppressor genes in nasopharyngeal carcinoma. (2006) (23)
- MAML1 Enhances the Transcriptional Activity of Runx2 and Plays a Role in Bone Development (2013) (23)
- Context-Dependent Modulation of Replication Activity of Saccharomyces cerevisiae Autonomously Replicating Sequences by Transcription Factors (1999) (23)
- Runx3 is required for the specification of TrkC-expressing mechanoreceptive trigeminal ganglion neurons (2010) (22)
- Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis (2021) (22)
- RUNX3 interactome reveals novel centrosomal targeting of RUNX family of transcription factors (2012) (21)
- A Role for RUNX3 in Inflammation-Induced Expression of IL23A in Gastric Epithelial Cells (2014) (21)
- Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression (2016) (20)
- The chimeric protein, PEBP2β/CBFβ-SMMHC, disorganizes cytoplasmic stress fibers and inhibits transcriptional activation (1998) (20)
- Enhancement of polyoma virus middle T antigen tyrosine phosphorylation by epidermal growth factor (1983) (20)
- Neuroblastoma cell proliferation is sensitive to changes in levels of RUNX1 and RUNX3 protein. (2011) (19)
- A RUNX2/PEBP2αA/CBFA1 mutation in cleidocranial dysplasia revealing the link between the gene and Smad (2001) (19)
- Loss of Runx3 affects ovulation and estrogen‐induced endometrial cell proliferation in female mice (2008) (19)
- Roles of RUNX in Solid Tumors. (2017) (19)
- The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression. (2010) (19)
- In vitro differentiation of Runx3−/–p53−/– gastric epithelial cells into intestinal type cells (2008) (18)
- RUNX3 Downregulation in Human Lung Adenocarcinoma is Independent of p53, EGFR or KRAS Status (2012) (18)
- Cloning and expression pattern of a novel PEBP2β-binding protein (charged amino acid rich leucine zipper-1 [Crl-1]) in the mouse (2001) (18)
- The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament (2017) (18)
- TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. (2015) (18)
- CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer (2016) (17)
- Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair (2020) (17)
- Functional relationship between p53 and RUNX proteins (2018) (17)
- Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia. (2007) (17)
- Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons (2013) (16)
- RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point (2019) (16)
- Transcription factor Runx1 recruits the polyomavirus replication origin to replication factories (2007) (16)
- Abolishment of c‐fos Inducibility in ras‐Transformed Mouse Osteoblast Cell Lines (1989) (16)
- The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates (2014) (16)
- Inactivation of RUNX3 by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression (2008) (15)
- Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells (2020) (15)
- Runx3 expression during mouse tongue and palate development. (2006) (14)
- Regulation of c‐fos gene transcription and myeloid cell differentiation by acute myeloid leukemia 1 and acute myeloid leukemia‐MTG8, a chimeric leukemogenic derivative of acute myeloid leukemia 1 (1999) (13)
- Granulocyte Macrophage-Colony Stimulating Factor-dependent Replication of Polyoma Virus Replicon in Hematopoietic Cells (1995) (12)
- The Multiple Interactions of RUNX with the Hippo–YAP Pathway (2021) (12)
- Role of TAp73α in induction of apoptosis by transforming growth factor‐β in gastric cancer cells (2008) (12)
- Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis (2017) (12)
- Suppressive Effect of (-)-Epigallocatechin Gallate on Aflatoxin B1-induced Chromosome Aberrations in Rat Bone Marrow Cells (2001) (12)
- RUNX Proteins in Development and Cancer (2017) (12)
- Bhlha9 regulates apical ectodermal ridge formation during limb development (2017) (12)
- Analysis of transcription factors expressed at the anterior mouse limb bud (2017) (11)
- FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway (2019) (11)
- Detection of polyoma‐virus‐induced tumor antigen(S) by macrophage migration inhibition (1982) (10)
- Ablation of miR-146b in mice causes hematopoietic malignancy. (2018) (10)
- A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity. (2017) (10)
- Comment on Levanon et al., ‘Runx3 knockouts and stomach cancer’, in EMBO reports (June 2003) (2003) (9)
- The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA (2020) (9)
- In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues (2012) (9)
- A Systems Approach and Skeletal Myogenesis (2012) (9)
- Genetic evidence of PEBP2β-independent activation of Runx1 in the murine embryo (2008) (8)
- DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia (2020) (8)
- The Fanconi Anemia Pathway of DNA Repair and Human Cancer (2015) (7)
- Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates (2019) (7)
- RUNX3 is expressed in the epithelium of the gastrointestinal tract (2012) (7)
- Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids (2021) (7)
- Lack of RUNX3 inactivation in columnar cell lesions of breast (2010) (7)
- Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia (2005) (7)
- Induction of gastric cancer by successive oncogenic activation in the corpus. (2021) (6)
- Haploinsufficiency of Runx 1 / AML 1 promotes myeloid features and leukaemogenesis in BXH 2 mice (2005) (6)
- Human T-Cell Retrovirus and Adult T-Cell Lymphoma and Leukemia: Possible Factors on Viral Incidence (1983) (6)
- The Transcription Factor Runx 3 Represses the Neurotrophin Receptor TrkB during Lineage Commitment of Dorsal Root Ganglion Neurons * (2007) (6)
- Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines. (2021) (6)
- In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System (2020) (6)
- Role of bone morphogenetic protein signaling in colorectal cancer (2007) (5)
- A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach (2022) (5)
- E1A physically interacts with RUNX3 and inhibits its transactivation activity (2008) (5)
- RUNX3 loss turns on the dark side of TGF-beta signaling (2017) (5)
- PEBP2 β /CBF β -dependent phosphorylation of RUNX1 and p300 by HIPK2: Implications for leukemogenesis (2008) (5)
- of the Drosophila Runt Gene and the Human AML1 Gene PEBP2/PEA2 Represents a Family of Transcription Factors Homologous to the Products (2007) (4)
- Runx1/AML1 is a Guardian of Hematopoietic Stem Cells (2008) (4)
- Okadaic acid reverses the inhibitory effect of protein kinase C on alkaline phosphatase activity in osteoblast-like cells (1994) (4)
- Role of RUNX 3 in Bone Morphogenetic Protein Signalling in Colorectal Cancer (2019) (4)
- MOLECULAR INSIGHTS INTO PEBP2/CBF-SMMHC ASSOCIATED ACUTE LEUKEMIA REVEALED FROM THE THREE-DIMENSIONAL STRUCTURE OF PEBP2/CBF BETA (2000) (3)
- Aurora kinase and RUNX: Reaching beyond transcription (2016) (3)
- Corrigendum to “Runx1 is involved in the fusion of the primary and the secondary palatal shelves” [Dev. Biol. 326 (2009) 392–402] (2009) (3)
- The H. pylori CagA Oncoprotein Induces DNA Double Strand Breaks through Fanconi Anemia Pathway Downregulation and Replication Fork Collapse (2022) (2)
- The myeloid features of BXH2 leukemias may result from the lack of one copy of the repetitive sequence in the long terminal repeat viral enhancer (2007) (2)
- K-Ras–Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated (2020) (2)
- Suppressive effect of (-)-epigallocatechin gallate on 7,12-dimethylbenz[a]anthracene-induced chromosome aberrations in rat bone marrow cells (2005) (1)
- RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21 Expression in Cooperation with Transforming Growth Factor (cid:2) -Activated SMAD (2005) (1)
- RUNX3 in Stem Cell and Cancer Biology (2023) (1)
- Long‐Evans A and C Rat Strains Susceptible to Clastogenic Effects of Chemicals in the Bone Marrow Cells (1994) (1)
- MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes. (2020) (1)
- Retroviral integration sites (RIS) mark cis-regulatory elements. (2009) (1)
- Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer (2022) (1)
- A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells. (2022) (1)
- Foxf2 represses bone formation via Wnt2b/β-catenin signaling (2022) (1)
- implications for mechanisms of pathogenesis familial platelet disorder with predisposition to acute myelogenous leukemia: In vitro analyses of known and novel RUNX1/AML1 mutations in dominant (2013) (1)
- Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells (2021) (1)
- The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells (2020) (1)
- An Organoid Approach to Target Her2/PD‐L1 Positive Gastric Cancers (2020) (1)
- Virus-specific proteins intheplasma membraneofcells lytically infected ortransformed bypolyoma virus (1977) (0)
- Abstract B02: Elevated YAP expression associates with EMT, stemness, and angiogenic properties of TNBC cell lines and recurrence in TNBC patients (2020) (0)
- Title MAML 1 Enhances the Transcriptional Activity of Runx 2 and Plays a Rolein Bone Development (2017) (0)
- 590 AN ORGANOID-IMMUNE CELL CO-CULTURE PREDICTIVE MODEL TO TARGET HER2/PD-L1 POSITIVE GASTRIC CANCERS (2020) (0)
- distinct from AP-1. 12-O-tetradecanoylphorbol-13-acetate but PEBP5, responsive to A polyomavirus enhancer-binding protein, (2013) (0)
- Abstract A43: RUNX3 and pRB form a complex and regulate restriction-point commitment (2014) (0)
- Identification oftwodistinct elements inthelongterminal repeat ofHTLV-Iresponsible formaximumgeneexpression (1987) (0)
- activation in leukemogenesis Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 (2011) (0)
- Abstract 2618: IQGAP3 regulates intra-cellular Ras signaling and intra-tumoral malignant cycles via TGFβ signaling (2023) (0)
- Characterization of polyoma virus T antigen (rat antiserum against tumor antigen/Staphylococcus protein A/ts A mutants/protein modification/cell transformation) (2016) (0)
- PEBP2- (cid:1) /CBF- (cid:1) –dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis (2008) (0)
- , K transcription factor PEBP 2 / CBF . subunits of the acute myeloid leukemia-linked Subcellular localization of the alpha and beta (1995) (0)
- AML-1-Ets-1 interaction : an aspect of tissue specific gene expression (1998) (0)
- Identification of Marker Genes That Discriminate between Different Myeloproliferative Disorders and Normal Individuals Including RUNX3 (AML2). (2005) (0)
- RUNX3 antagonizes the effect of the Notch signalling pathway in the development and maintenance of the intestinal epithelium (2007) (0)
- MicroRNAs in Chronic Inflammation (2016) (0)
- Identification of RUNX1 enhancer element that targets tissue stem cells of gastric and other organs (2017) (0)
- after Transformation of NIH3T3Cells bytheHa-rasOncogenet (1989) (0)
- Title Context-dependent activation of Wnt signaling by tumor suppressorRUNX 3 in gastric cancer cells (2017) (0)
- Abstract LB-138: Runx1 enhancer element marks stem cells in multiple organs (2017) (0)
- leukemogenic inversion 16 chimera Molecular basis for a dominant inactivation of RUNX1/AML1 by the (2013) (0)
- 067 CARTILAGE-SPECIFIC MICRORNA-140 REGULATES TISSUE HOMEOSTASIS AND PROTECTS AGAINST OSTEOARTHRITIS-LIKE PATHOLOGY (2010) (0)
- RUNX3 and SHH in medulloblastoma (2008) (0)
- Expression of the Runt Domain-Encoding PEBP2 (cid:97) Genes in T Cells during Thymic Development (1995) (0)
- Middle T Antigen asPrimary Inducer ofFullExpression of thePhenotype ofTransformation byPolyomaVirus (1980) (0)
- Abstract 2960: Identification of Runx3 as a gatekeeper of lung adenocarcinoma (2014) (0)
- Molecular Oncology: Gastric cancer (2013) (0)
- RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs (2022) (0)
- Identification of tissue stem cell specific enhancer element (2016) (0)
- Post-Transcriptional Gene Regulation by MicroRNA and RNA-Binding Protein (2016) (0)
- deficiency results in myeloproliferative disorder in aged mice Runx3 (2013) (0)
- Identification of eR1 that marks luminal stem/progenitor cells in mammary gland (2017) (0)
- Runx 2 Regulates C / EBP d Expression by Osteoblasts 21747 (2000) (0)
- Abstract LB-139: Tissue stem cell specific enhancer element identifies two types of stem cells in the corpus epithelium of the stomach (2015) (0)
- Proliferative and quiescent human gastric cancer stem-like cells are associated with differential chemoresistance and patient mortality (2022) (0)
- Runx3 is required for the specification of TrkC-positive mechanoreceptive neurons in the trigeminal ganglion (2009) (0)
- Physical interactions between AML1/PEBP2αB1 and Ets-1. (1996) (0)
- Epigenetic Factors: Key Regulators Targeted in Cancers (2018) (0)
- Identification of a cis-regulatory element which may drive Runx1 expression in hematopoietic stem cells (2007) (0)
- Gene Associated With Myeloblastic Leukemias AML1/PEBP2?B Biallelic and Heterozygous Point Mutations in the Runt Domain of the (2013) (0)
- Tendon regeneration and development by transcription factor Mkx (2016) (0)
- Chapter 5 Epigenetic Factors : Key Regulators Targeted in Cancers (2019) (0)
- Identification of the replication activation domain of PEBP2/AML1 (1996) (0)
- Abstract 919: Identification of stem cells in stomach corpus and antrum (2017) (0)
- A novel AML1 transcript encoding the N-terminally truncated AML1 : A possible new regulatory mechanism (1996) (0)
- myeloid leukemia chimeric gene in t(8;21)(q24;q22) acute AML1-TRPS1 factors by the Concurrent transcriptional deregulation of AML1/RUNX1 and GATA (2008) (0)
- leukemia Heterozygous PU.1 mutations are associated with acute myeloid (2011) (0)
- Epigenetic inactivation of RUNX3 in preneoplastic lesions of colorectum (2007) (0)
- The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA (2020) (0)
- Chief cell in stomach have stem cell activity and potential to develop gastric cancer (2019) (0)
- Wwp2 maintains cartilage homeostasis through regulation of Adamts5 (2019) (0)
- Abstract 19241: Androgen Receptor Associated Molecule, Ara70, Modulates Postnatal Neovascularization (2017) (0)
- Escort1 regulates expression of inflammatory cytokines (2016) (0)
- Abstract LB-5: RUNX3 targets estrogen receptorαfor proteasome-mediated degradation suppressing breast cancer tumorigenesis (2010) (0)
- Transplantation of autologous bone marrow with platelet-rich plasma into osteonecrosis of femoral head: A report of three cases (2008) (0)
- Title Role of RUNX 3 in bone morphogenetic protein signaling in colorectalcancer (2019) (0)
- T2060 The Prevalence of Cardia Inflammation and Pre-Cancerous Lesions in a High Risk Chinese Cohort Being Screened for Gastric Cancer (2008) (0)
- Genetic, Epigenetic, and MicroRNA Regulation of Osteoarthritis (2020) (0)
- Possible roles of cAMP-specific phosphodiesterases in cell cycle progression of cultured FRTL-5 thyroid cells induced by TSH and IGF-I (2002) (0)
- Abstract 5110: Runx knockout in breast luminal stem/progenitor cells induced precancerous lesion via robust expression of ERα (2018) (0)
- Role of microRNA in cartilage homeostasis (2017) (0)
- Runx1 enhancer element marks stem/progenitor cells in pancreas and can be an origin of cancer. (2018) (0)
- Identification of Cooperating Genetic Alterations in RUNX Leukemia Using the Mouse Model for the Human Familial Leukemia, FPD/AML. (2004) (0)
- RUNX3 represses neurotrophin receptor TrkB in neuroblastoma (2007) (0)
- Antitumor activity pointing runx3 gene and its use (2001) (0)
- STAT3 activation is essential for t(8;21) RUNX1-ETO leukemogenesis. (2007) (0)
- Opposing actions of RUNX3 and the Wnt pathway on the CDX2 promoter in gastric epithelial cells (2007) (0)
- Abstract 1570: Loss of mismatch repair protein MSH6 sensitizes diffuse-type gastric cancer cells to DNA-PKcs inhibitor KU60648 (2018) (0)
- Roles of transcriptional factor Mkx in PDL (2015) (0)
- Transcriptional factor Mkx affects neurovascular related genes in PDL. (2017) (0)
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What Schools Are Affiliated With Yoshiaki Ito?
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