Yoshihiro Hayakawa
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Computer Science
Yoshihiro Hayakawa's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Yoshihiro Hayakawa's Published Works
Published Works
- STING is a direct innate immune sensor of cyclic-di-GMP (2011) (1203)
- Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells (2001) (756)
- New aspects of natural-killer-cell surveillance and therapy of cancer (2002) (728)
- CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity1 (2006) (726)
- Activation of NK cell cytotoxicity. (2005) (632)
- Critical contribution of liver natural killer T cells to a murine model of hepatitis. (2000) (567)
- The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. (2013) (553)
- Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence. (2006) (541)
- The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides (2010) (481)
- Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development (2002) (475)
- A cyclic-di-GMP receptor required for bacterial exopolysaccharide production (2007) (434)
- CD4+CD25+ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer1 (2006) (423)
- Differential antitumor immunity mediated by NKT cell subsets in vivo (2005) (404)
- Cytokines in cancer immunity and immunotherapy (2004) (399)
- Nature's TRAIL--on a path to cancer immunotherapy. (2003) (373)
- The second messenger bis‐(3′‐5′)‐cyclic‐GMP and its PilZ domain‐containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa (2007) (338)
- NKG2D function protects the host from tumor initiation (2005) (334)
- Glycolipid Antigen Drives Rapid Expansion and Sustained Cytokine Production by NK T Cells 1 (2003) (318)
- NKT cells - conductors of tumor immunity? (2002) (316)
- NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation1 (2007) (296)
- A nonclassical non-Vα14Jα18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance (2005) (292)
- Type I IFN Contributes to NK Cell Homeostasis, Activation, and Antitumor Function1 (2007) (289)
- A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP (2009) (279)
- TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. (2005) (275)
- TRAIL and its receptors as targets for cancer therapy (2004) (254)
- Differential Regulation of Th1 and Th2 Functions of NKT Cells by CD28 and CD40 Costimulatory Pathways1 (2001) (241)
- Control of Formation and Cellular Detachment from Shewanella oneidensis MR-1 Biofilms by Cyclic di-GMP (2006) (240)
- Functional subsets of mouse natural killer cells (2006) (238)
- NK Cell TRAIL Eliminates Immature Dendritic Cells In Vivo and Limits Dendritic Cell Vaccination Efficacy 1 (2004) (225)
- Innate Immune Surveillance of Spontaneous B Cell Lymphomas by Natural Killer Cells and γδ T Cells (2004) (220)
- Bacterial c-di-GMP Is an Immunostimulatory Molecule1 (2007) (213)
- Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody Therapy (2004) (206)
- Cutting Edge: Tumor Rejection Mediated by NKG2D Receptor-Ligand Interaction Is Dependent upon Perforin1 (2002) (206)
- Critical contribution of IFN‐γ and NK cells, but not perforin‐mediated cytotoxicity, to anti‐metastatic effect of α‐galactosylceramide (2001) (196)
- The Dark Side of IFN-γ: Its Role in Promoting Cancer Immunoevasion (2017) (195)
- NKG2D Recognition and Perforin Effector Function Mediate Effective Cytokine Immunotherapy of Cancer (2004) (186)
- IL-21 Induces the Functional Maturation of Murine NK Cells 1 (2004) (184)
- Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer (2005) (183)
- IFN-γ–mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, α-galactosylceramide (2002) (173)
- STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer (2014) (173)
- Perforin‐dependent NK cell cytotoxicity is sufficient for anti‐metastatic effect of IL‐12 (1999) (165)
- Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. (2001) (163)
- RIG‐I detects infection with live Listeria by sensing secreted bacterial nucleic acids (2012) (150)
- α-Galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis (2003) (147)
- IL-21 induces the functional maturation of murine NK cells. (2006) (146)
- c-di-GMP (3′-5′-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation (2005) (142)
- Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. (2015) (136)
- IL-21 Enhances Tumor Rejection through a NKG2D-Dependent Mechanism1 (2005) (134)
- CD27-Mediated Activation of Murine NK Cells1 (2000) (133)
- The allylic protection method in solid-phase oligonucleotide synthesis. An efficient preparation of solid-anchored DNA oligomers (1990) (127)
- Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer. (2003) (119)
- The Interactions of Multiple Cytokines Control NK Cell Maturation (2010) (118)
- A new adjuvant delivery system 'cyclic di-GMP/YSK05 liposome' for cancer immunotherapy. (2014) (116)
- Genome-wide Transcriptional Profile of Escherichia coli in Response to High Levels of the Second Messenger 3′,5′-Cyclic Diguanylic Acid* (2006) (113)
- Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2 (2015) (112)
- Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses (2013) (111)
- Allyloxycarbonyl group: a versatile blocking group for nucleotide synthesis (1986) (107)
- Cyclic Di-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia (2007) (106)
- IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting (2017) (103)
- Carbon-carbon bond formation promoted by transition metal carbonyls. 17. Reactions of polybromo ketones with 1,3-dienes in the presence of iron carbonyls. New 3 + 4 .fwdarw. 7 cyclocoupling reaction forming 4-cycloheptenones (1978) (98)
- IFN-gamma-mediated inhibition of tumor angiogenesis by natural killer T-cell ligand, alpha-galactosylceramide. (2002) (96)
- NKG2D and cytotoxic effector function in tumor immune surveillance. (2006) (94)
- Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12. (2000) (94)
- Oral Administration of a Kampo (Japanese Herbal) Medicine Juzen‐taiho‐to Inhibits Liver Metastasis of Colon 26‐L5 Carcinoma Cells (1998) (90)
- 3',5'-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation. (2005) (84)
- 3′,5′-Cyclic Diguanylic Acid Reduces the Virulence of Biofilm-Forming Staphylococcus aureus Strains in a Mouse Model of Mastitis Infection (2005) (82)
- c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection. (2008) (82)
- Analysis of the Borrelia burgdorferi Cyclic-di-GMP-Binding Protein PlzA Reveals a Role in Motility and Virulence (2011) (82)
- Combination Therapy of Established Tumors by Antibodies Targeting Immune Activating and Suppressing Molecules (2010) (81)
- Application of CD27 as a marker for distinguishing human NK cell subsets. (2008) (79)
- Correction for Kulesekara et al., Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence (2006) (79)
- Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis (2014) (78)
- Innate immune recognition and suppression of tumors. (2006) (78)
- Alpha-galactosylceramide: potential immunomodulatory activity and future application. (2004) (78)
- AKT-STAT3 Pathway as a Downstream Target of EGFR Signaling to Regulate PD-L1 Expression on NSCLC cells (2016) (77)
- Gene-Engineered T Cells as a Superior Adjuvant Therapy for Metastatic Cancer1 (2004) (77)
- Regulation of antitumour immunity by CD1d-restricted NKT cells. (2004) (76)
- IFN‐γ production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice (2011) (75)
- Critical contribution of IFN-gamma and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of alpha-galactosylceramide. (2001) (70)
- A stereocontrolled general synthesis of C-nucleosides (1978) (68)
- c-di-GMP as a vaccine adjuvant enhances protection against systemic methicillin-resistant Staphylococcus aureus (MRSA) infection. (2009) (67)
- Quantification of mouse pulmonary cancer models by microcomputed tomography imaging (2009) (67)
- O-selective phosphorylation of nucleosides without N-protection (1993) (66)
- Peripheral natural killer cell maturation depends on the transcription factor Aiolos (2014) (61)
- Facile Synthesis of Oligodeoxyribonucleotides via the Phosphoramidite Method without Nucleoside Base Protection (1998) (61)
- Acid/azole complexes as highly effective promoters in the synthesis of DNA and RNA oligomers via the phosphoramidite method. (2001) (61)
- STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation (2021) (60)
- The Anaplasma phagocytophilum PleC Histidine Kinase and PleD Diguanylate Cyclase Two-Component System and Role of Cyclic Di-GMP in Host Cell Infection (2008) (59)
- IFN-γ-Dependent Recruitment of Mature CD27high NK Cells to Lymph Nodes Primed by Dendritic Cells (2008) (59)
- IFN-γ-mediated negative feedback regulation of NKT cell function by CD94/NKG2 (2005) (58)
- Parallels and distinctions between T and NKT cell development in the thymus (2004) (58)
- Cyclic di-GMP Signaling Regulates Invasion by Ehrlichia chaffeensis of Human Monocytes (2010) (56)
- Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis. (2016) (55)
- A facile synthesis of cyclic bis(3′→5′)diguanylic acid (2003) (54)
- Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors (2004) (53)
- Benzimidazolium Triflate as an Efficient Promoter for Nucleotide Synthesis via the Phosphoramidite Method. (1996) (52)
- Cutting Edge: Novel Priming of Tumor-Specific Immunity by NKG2D-Triggered NK Cell-Mediated Tumor Rejection and Th1-Independent CD4+ T Cell Pathway1 (2004) (52)
- Biochemical and physiological characterization of a BLUF protein-EAL protein complex involved in blue light-dependent degradation of cyclic diguanylate in the purple bacterium Rhodopseudomonas palustris. (2010) (50)
- Berberine enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast cancer (2013) (50)
- Novel cyclopentenone synthesis via the iron carbonyl aided cyclocoupling between .alpha.,.alpha.'-dibromo ketones and enamines (1978) (49)
- Identification of a Streptococcus pyogenes SF370 gene involved in production of c-di-AMP. (2011) (47)
- Carbon-carbon bond formations promoted by transition metal carbonyls. XI. Method for the generation of a synthetic equivalent of unsubstituted oxyallyl via the bromo ketone-iron carbonyl reaction. New route to thujaplicins (1975) (46)
- Carbon-carbon bond formation promoted by transition metal carbonyls. 18. New synthesis of troponoid compounds via the iron carbonyl promoted cyclocoupling between polybromo ketones and 1,3-dienes (1978) (46)
- Carbon-carbon bond formation promoted by transition metal carbonyls. 16. Reaction of .alpha.,.alpha.'-dibromo ketones and iron carbonyls. Mechanistic aspects (1978) (44)
- O-allyl protection of guanine and thymine residues in oligodeoxyribonucleotides (1993) (44)
- Interleukin 21: a key player in lymphocyte maturation. (2004) (44)
- IFN-gamma-dependent recruitment of mature CD27(high) NK cells to lymph nodes primed by dendritic cells. (2008) (44)
- New, general synthesis of tropane alkaloids (1974) (41)
- IL-21 Enhances Tumor-Specific CTL Induction by Anti-DR5 Antibody Therapy1 (2006) (41)
- Carbon-carbon bond formation promoted by transition metal carbonyls. 19. General synthesis of tropane alkaloids via the polybromo ketone-iron carbonyl reaction (1978) (41)
- An Improved Method for Synthesizing Cyclic Bis(3′–5′)diguanylic Acid (c-di-GMP) (2004) (40)
- Identification of ligand analogues that control c-di-GMP riboswitches. (2012) (40)
- Molecular oxygen regulates the enzymatic activity of a heme-containing diguanylate cyclase (HemDGC) for the synthesis of cyclic di-GMP. (2010) (38)
- NKG2A Inhibits Invariant NKT Cell Activation in Hepatic Injury1 (2009) (38)
- RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer (2014) (37)
- Patients with multiple myeloma treated with thalidomide: evaluation of clinical parameters, cytokines,angiogenic markers, mast cells and marrow CD57+ cytotoxic T cells as predictors of outcome. (2007) (37)
- Carbon-carbon bond formations promoted by transition metal carbonyls. III. Mechanistic aspects of the reaction of .alpha.,.alpha.1-dibromo ketones and iron carbonyl. Reductive rearrangements of dibromo ketones (1972) (37)
- Mesenchymal-transitioned cancer cells instigate the invasion of epithelial cancer cells through secretion of WNT3 and WNT5B (2014) (37)
- Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING. (2015) (36)
- Procyanidin C1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in the A549 lung cancer cell line. (2013) (35)
- Differential expression of integrin subunits in DU-145/AR prostate cancer cells. (2004) (34)
- Critical contribution of MCL-1 in EMT-associated chemo-resistance in A549 non-small cell lung cancer. (2015) (34)
- NK Cells Control Tumor-Promoting Function of Neutrophils in Mice (2018) (33)
- IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. (2005) (33)
- Carbon-carbon bond formations promoted by transition metal carbonyls. II. Reaction of .alpha.,.alpha.1-dibromo ketones and enamines with the aid of iron carbonyls. Novel cyclopentenone synthesis (1972) (33)
- HPLC analysis of juzen-taiho-to and its variant formulations and their antimetastatic efficacies. (1999) (32)
- Survivin suppression through STAT3/β-catenin is essential for resveratrol-induced melanoma apoptosis. (2014) (32)
- Allyl protection of internucleotide linkage (1985) (32)
- Preparation of Short Oligonucleotides via the Phosphoramidite Method Using a Tetrazole Promoter in a Catalytic Manner (1997) (32)
- Anti-metastatic and immunomodulating properties of the water extract from Celosia argentea seeds. (1998) (31)
- IL‐17A‐producing CD30+ Vδ1 T cells drive inflammation‐induced cancer progression (2016) (31)
- ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets (2017) (29)
- Synthesis of cyclic bis(3′-5′)diguanylic acid (c-di-GMP) analogs (2006) (29)
- Carbon-carbon bond formation promoted by transition metal carbonyls. 20. Iron carbonyl promoted reaction of .alpha.,.alpha.'-dibromo ketones and aromatic olefins leading to 3-arylcyclopentanones. The [3 + 2] cycloaddition involving an allylic cation (1978) (29)
- Molecular mechanisms of natural compounds in cell death induction and sensitization to chemotherapeutic drugs in lung cancer (2019) (28)
- Identification of Hirsutine as an anti-metastatic phytochemical by targeting NF-κB activation. (2014) (28)
- Total synthesis of dl-dendrobine. (1972) (27)
- Additions and Corrections - Intramolecular Dibromo Ketone-Iron Carbonyl Reaction in Terpene Synthesis (1979) (27)
- Carbon-carbon bond formations promoted by transition metal carbonyls. 15. Regioselectivity of the iron carbonyl promoted cyclocoupling reaction of .alpha.,.alpha.'-Dibromo ketones with olefins and dienes (1977) (27)
- Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis (2018) (27)
- Natural Product Synthesis via the Polybromo Ketone ‐ Iron Carbonyl Reaction (1985) (27)
- Carbon-carbon bond formations promoted by transition metal carbonyls. VIII. Iron carbonyl promoted reaction of .alpha.,.alpha.'-dibromo ketones and carboxamides. Convenient route to muscarines via furanones (1973) (26)
- A Stereocontrolled Total Synthesis of C-Nucleosides (1984) (25)
- Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation (2015) (24)
- Herbal Medicine Goshajinkigan Prevents Paclitaxel-Induced Mechanical Allodynia without Impairing Antitumor Activity of Paclitaxel (2013) (24)
- Synthesis of 3(2H)-Furanones by the Iron Carbonyl-promoted Cyclocoupling Reaction of α,α′-Dibromo Ketones and Carboxamides. A Convenient Route to Muscarines (1977) (24)
- c-di-GMP Enhances Protective Innate Immunity in a Murine Model of Pertussis (2014) (23)
- Distinct receptor repertoire formation in mouse NK cell subsets regulated by MHC class I expression (2008) (23)
- Subset analysis of human and mouse mature NK cells. (2010) (23)
- Targeting NKG2D in tumor surveillance (2012) (23)
- Antimetastatic and immunomodulating properties of a new herbal prescription, Bojung-bangam-tang. (2003) (22)
- Early activation and interferon‐γ production of tumor‐infiltrating mature CD27high natural killer cells (2011) (22)
- Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus (2021) (22)
- General Synthesis and Binding Affinity of Position-Selective Phosphonodiester- and Phosphotriester-Incorporated Oligodeoxyribonucleotides (1995) (22)
- Ethyl(methyl)dioxirane as an efficient reagent for the oxidation of nucleoside phosphites into phosphates under nonbasic anhydrous conditions. (2001) (22)
- A convenient-method for the formation of internucleotide linkage (1984) (22)
- Toward an Ideal Synthesis of Oligonucleotides : Development of a Novel Phosphoramidite Method with High Capability^# (2001) (22)
- Use of Allylic Protecting Groups for the Synthesis of Base‐Sensitive Prooligonucleotides (2002) (21)
- Selective anticancer activity of hirsutine against HER2‑positive breast cancer cells by inducing DNA damage. (2015) (21)
- Lung‐resident natural killer cells control pulmonary tumor growth in mice (2018) (20)
- A Novel Uncoupler of Mitochondrial Respiration, 9, 10-Epoxy-12-octadecenoate, Exists in Human Burned Skin (1986) (20)
- CD27-Mediated Activation of Murine NK Cells (2000) (20)
- Stereocontrolled synthesis of showdomycin and 6-azapseudouridines☆ (1978) (19)
- Controlling Glycosyl Bond Conformation of Guanine Nucleosides: Stabilization of the anti Conformer in 5'-O-Ethylguanosine. (2012) (19)
- Identification of plant extracts sensitizing breast cancer cells to TRAIL. (2013) (19)
- Asialoglycoprotein receptor promotes cancer metastasis by activating the EGFR-ERK pathway. (2011) (19)
- Synthesis of 2′-5′,3′-5′ linked triadenylates (1987) (19)
- A Strategy for the Stereoselective Preparation of Thymidine Phosphorothioates with the (R) or the (S) Configuration at the Stereogenic Phosphorus Atom and Their Application to the Synthesis of Oligodeoxyribonucleotides with Stereochemically Pure Phosphate/Phosphorothioate Chimeric Backbones (2006) (18)
- Phosphoramidite solid-phase synthesis of site-specifically glycosylated oligodeoxynucleotides (2000) (18)
- Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells. (2017) (18)
- Carbon-carbon bond formations promoted by transition metal carbonyls. VII. Reaction of .alpha.,.alpha.'-dibromo ketones and aromatic olefins promoted by iron carbonyl. Cationic 3 + 2 .far. 5 cycloaddition (1973) (18)
- Innate tumor immune surveillance. (2007) (18)
- Effect of cyclic bis(3′–5′)diguanylic acid and its analogs on bacterial biofilm formation (2009) (18)
- Chemical synthesis of cytidine-5'-monophosphono-N-acetylneuraminic acid (CMP-Neu5Ac) (1993) (18)
- Cyclic Dimeric GMP Signaling Regulates Intracellular Aggregation, Sessility, and Growth of Ehrlichia chaffeensis (2011) (18)
- Facile nucleoside phoshorylation via hydroxyl activation (1983) (17)
- Synthesis of carbocamphenilone and its 6,7-dehydro derivative (1975) (17)
- A PixD--PapB chimeric protein reveals the function of the BLUF domain C-terminal α-helices for light signal transduction. (2012) (16)
- A new synthetic route to oligoribonucleotides based on CpRu-catalyzed deallylation (2007) (16)
- Synthesis of fluorocyclohexadienes by the electrochemical fluorination of p-difluorobenzenes on a preparative scale (1995) (16)
- A new route to tropanes (1974) (15)
- The first asymmetric synthesis of trialkyl phosphates on the basis of dynamic kinetic resolution in the phosphite method using a chiral source in a catalytic manner (2003) (15)
- Evidence supporting the activity of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentafuranosylcytosine as a terminator in enzymatic DNA-chain elongation. (1998) (15)
- ChemInform Abstract: Effect of Molecular Sieves in the Liquid-Phase Synthesis of Nucleotides via the Phosphoramidite Method. (2001) (14)
- Functional roles of tumor necrosis factor‐related apoptosis‐inducing ligand–DR5 interaction in B16F10 cells by activating the nuclear factor‐κB pathway to induce metastatic potential (2013) (14)
- Role of Th1 and Th2 cytokines in regulating the liver injury induced by delayed-type hypersensitivity to picryl chloride. (1999) (14)
- Carboxylic acids as promoters for internucleotide-bond formation via condensation of a nucleoside phosphoramidite and a nucleoside: relationship between the acidity and the activity of the promoter (2005) (14)
- A Novel Synthesis of Oligonucleotide–Peptide Conjugates with a Base-Labile Phosphate Linker between the Two Components According to the Allyl-Protected Phosphoramidite Strategy (2000) (14)
- A new synthetic approach to cyclic bis(3'-->5')diguanylic acid. (2003) (14)
- P38 pathway as a key downstream signal of connective tissue growth factor to regulate metastatic potential in non‐small‐cell lung cancer (2016) (13)
- Stereochemistry of intermediates in the syntheses of alkaloids (1973) (13)
- Solid-phase synthesis of oligodeoxyribonucleotides using the bis(trimethylsilyl) peroxide oxidation of phosphites☆ (1986) (13)
- Chemoselective phosphorylation of N-unprotected nucleosides via aluminum alkoxides (1984) (13)
- Novel synthesis and characterization of bioconjugate block copolymers having oligonucleotides. (2005) (13)
- Facile synthesis of tricyclo[5.3.1.03,8]undecane and spiro[5.5]undecane systems from a common intermediate (1971) (13)
- Studies on the mechanism of the stereospecific polymerization. Asymmetric‐induction polymerization of benzofuran by use of optically active organo‐stannic compounds (1965) (13)
- Improved Methods for the Preparation of 2′-Deoxyribonucleoside and Ribonucleoside 3′-Phosphoramidites with Allylic Protectors (1999) (13)
- STING Ligand cdi-GMP Improves Cancer Vaccination against Metastatic Breast Cancer (2014) (13)
- Anti-metastatic Effects of Baicalein by Targeting STAT3 Activity in Breast Cancer Cells. (2020) (13)
- Anti-invasive activity of synthetic serine protease inhibitors and its combined effect with a matrix metalloproteinase inhibitor. (1998) (13)
- SOX10 Regulates Melanoma Immunogenicity through an IRF4–IRF1 Axis (2021) (13)
- A single-step synthesis of (±)-α-cuparenone (1978) (12)
- T Cells Gene-engineered with DAP12 Mediate Effector Function in an NKG2D-dependent and Major Histocompatibility Complex-independent Manner* (2005) (12)
- Reductive Dehalogenation of Polyhalo Ketones with Low‐Valent Metals and Related Reducing Agents (2005) (12)
- Pharmacological targeting of natural killer cells for cancer immunotherapy (2020) (12)
- Catalysts for asymmetric-induction polymerization of benzofuran. II. Properties and catalyses of some binary systems containing the menthoxy group (1967) (12)
- Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells (2017) (12)
- The Stereoselective Reduction of Tropinone to Tropine (1974) (12)
- Preparation of an Artificial Ribonucleoside with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Base and its Discriminating Ability for Natural Nucleosides (2007) (11)
- A convenient synthesis of 2'-5' linked oligoribonucleotides (1985) (11)
- Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma. (2017) (11)
- Iron carbonyl promoted reaction of α,α′-dibromo ketones and isobutylene. An ene reaction involving allylic cations☆ (1978) (11)
- In vivo imaging of obesity-induced inflammation in adipose tissue. (2010) (11)
- Analysis of the Borrelia burgdorferi Cyclic-di-GMP-Binding Protein PlzA Reveals a Role in Motility and Virulence (2011) (10)
- A NEW ROUTE TO NEZUKONE (1975) (10)
- Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices. (2014) (10)
- Nucleotide synthesis via methods without nucleoside-base protection. (2001) (10)
- STAM-binding protein regulates melanoma metastasis through SLUG stabilization. (2018) (10)
- Bis[3-(triethoxysilyl)propyl]tetrasulfide: the first liquid sulfur-transferring agent useful for conversion of nucleoside phosphites to the phosphorothioates (2005) (10)
- Synthesis of Cyclic Bis(3′‐5′)‐2′‐deoxyguanylic/guanylic Acid (c‐dGpGp) and Its Biological Activities to Microbes (2007) (10)
- A Convenient Method for the Synthesis of N-Free 5‘-O-(p,p‘-Dimethoxytrityl)-2‘- deoxyribonucleosides via the 5‘-O-Selective Tritylation of the Parent Substances (1999) (10)
- Practical Synthesis of 2'-5'-Linked Oligoadenylates (2-5A Oligomers) (1992) (9)
- Combined nano cancer immunotherapy based on immune status in a tumor microenvironment. (2022) (9)
- Organic Synthesis, Chemical Properties, and Biological Activities of Cyclic bis (3'-5') Diguanylic Acid (c-di-GMP) and Its Analogs (2006) (9)
- Chemical behavior of bis(3'-5')diguanylic acid in aqueous solutions. (2005) (9)
- Effect of Keishibukuryogan on Genetic and Dietary Obesity Models (2015) (9)
- Gas-phase isolation of diethyl guanosine 5'-monophosphate and its conformational assignment. (2010) (9)
- Organometallic methodologies for nucleic acid synthesis (1990) (9)
- Antiviral Effects of 2′,5′ Oligoadenylates (2‐5As), and Related Compounds (1990) (9)
- Synthetic studies on spirovetivanes. I. Spirocondensation of a 4-(3′-formylpropyl)-3-cyclohexenone and stereospecific total synthesis of d1-β-vetivone. (1973) (9)
- COP9 signalosome subunit 5 regulates cancer metastasis by deubiquitinating SNAIL (2018) (8)
- Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization (2020) (8)
- Utility of Azolium Triflates as Promoters for the Condensation of a Nucleoside Phosphoramidite and a Nucleoside in the Agrawal's Stereoselective Synthesis of Nucleoside Phosphorothioates (2005) (8)
- Erianthridin suppresses non-small-cell lung cancer cell metastasis through inhibition of Akt/mTOR/p70S6K signaling pathway (2021) (8)
- Proteasome Inhibitor-Loaded Micelles Enhance Antitumor Activity Through Macrophage Reprogramming by NF-κB Inhibition. (2017) (8)
- CARBON‐CARBON BOND FORMATION PROMOTED BY TRANSITION METAL CARBONYLS. 20. IRON N CARBONYL PROMOTED REACTION OF α,α′‐DIBROMO KETONES AND AROMATIC OLEFINS LEADING TO 3‐ARYLCYCLOPENTANONES. THE (3 + 2) CYCLOADDITION INVOLVING AN ALLYLIC CATION (1978) (7)
- Bufadienolides Overcome TRAIL Resistance in Breast Cancer Cells via JAK-STAT Pathway (2014) (7)
- Regiocontrolled General Synthesis of Branch-Type 2′-5′-Linked Oligoadenylates (1989) (7)
- Rational Combination Therapy for Melanoma with Dinaciclib by Targeting BAK-Dependent Cell Death (2019) (7)
- Russelioside A, a Pregnane Glycoside from Caralluma tuberculate, Inhibits Cell-Intrinsic NF-κB Activity and Metastatic Ability of Breast Cancer Cells. (2022) (7)
- Paclitaxel-induced hypothermia and hypoperfusion increase breast cancer metastasis and angiogenesis in mice (2017) (7)
- Anti-inflammatory activities of isopimara-8(14),-15-diene diterpenoids and mode of action of kaempulchraols P and Q from Kaempferia pulchra rhizomes. (2019) (7)
- Anti-inflammatory activities of isopimara-8(9),15-diene diterpenoids and mode of action of kaempulchraols B–D from Kaempferia pulchra rhizomes (2020) (7)
- Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation (2021) (6)
- Synthetic studies on spirovetivanes. II. Stereospecific total synthesis of dl-hinesol, dl-α-vetispirene, and dl-β-vetispirene (dl-β-isovetivenene). (1973) (6)
- Correction to Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells. (2017) (6)
- Inorganic Acid Derivatives (1991) (6)
- Peptide-nucleic acids (PNAs) with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) as a universal base: their synthesis and binding affinity for oligodeoxyribonucleotides. (2009) (5)
- A CONVENIENT ROUTE TO 4,5-HOMOTROPONES (1973) (5)
- Synthetic E-guggulsterone derivative GSD-1 inhibits NF-κB signaling and suppresses the metastatic potential of breast cancer cells. (2021) (5)
- Identification of Ophiocordyceps gracilioides by Its Anti-tumor Effects through Targeting the NFκB-STAT3-IL-6 Inflammatory Pathway. (2021) (5)
- Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF-κB pathway (2020) (5)
- Selective binding of carotenoids with a shorter conjugated chain to the LH2 antenna complex and those with a longer conjugated chain to the reaction center from Rubrivivax gelatinosus. (2007) (5)
- Allyl protection in the synthesis of oligodeoxyribonucleotide phosphorothioates (1994) (5)
- Preparation of (R)-(-)-2-Methoxy-2'-(1H-tetrazol-5-yl)-1,1'-binaphthyl and (1R,2R)-(+)-1-Trimethylsilyl-2-(1H-tetrazol-5-yl)ferrocene: Optically Active Tetrazoles with Axial or Planar Chirality (1997) (5)
- Stereochemistry of the electrophilic olefinic substitution of 2-oxyallyl--iron (II). Species. Inspection of the conformation of the zwitterionic intermediates1 (1976) (4)
- Cyclopentenones from α,α′‐Dibromoketones and Enamines: 2,5‐Dimethyl‐3‐Phenyl‐2‐Cyclopenten‐1‐One (2003) (4)
- Vaccination with B7-1+ Tumor and Anti-Adhesion Therapy with RGD Pseudo-Peptide (FC-336) Efficiently Induce Anti-Metastatic Effect (1998) (4)
- Immunopharmacological properties of Oren-gedoku-to (a Kampo medicine, Huang-Lian-Jie-Du-Tang) on contact hypersensitivity reaction in mice (2002) (4)
- Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice (2021) (4)
- Regulation of antitumour immunity by CD1d‐restricted NKT cells (2004) (4)
- Synthetic intermediate potentially useful for the synthesis of dendrobine (1971) (4)
- ASK1 suppresses NK cell‐mediated intravascular tumor cell clearance in lung metastasis (2021) (4)
- A novel approach to oligodeoxyribonucleotides bearing phosphoric acid esters at the 3′-terminals via the phosphoramidite method with allyl protection: An efficient synthesis of base-labile nucleotide-amino acid and -peptide conjugates (1999) (4)
- A CONVENIENT WAY TO N-ALLYLOXYCARBONYL PROTECTED ADENOSINE AND CYTIDINE DERIVATIVES (1998) (4)
- Report on the use of non‐clinical studies in the regulatory evaluation of oncology drugs (2016) (4)
- PRO-OLIGONUCLEOTIDE SYNTHESIS USING ALLYL AND ALLYLOXYCARBONYL PROTECTIONS: DIRECT MALDI-TOF MS ANALYSIS ON SOLID SUPPORT (2001) (4)
- Regiodefined synthesis and conformational properties of adenyldiyl trimers with unsymmetrical 2′–5′ and 3′–5′ internucleotide linkages (1995) (4)
- Antimetastatic effects of thalidomide by inducing the functional maturation of peripheral natural killer cells (2020) (4)
- Design and synthesis of 2-Substituted-4-benzyl-5-methylimidazoles as new potential Anti-breast cancer agents to inhibit oncogenic STAT3 functions. (2021) (3)
- A Facile Method for the Oxidation of Nucleoside H-Phosphonates to Phosphates with Bis(trimethylsilyl) Peroxide (1999) (3)
- Anti-metastatic effects of ergosterol peroxide from the entomopathogenic fungus Ophiocordyceps gracilioides on 4T1 breast cancer cells (2021) (3)
- Synthesis of 2'-end-modified 2'-5'-oligoadenylates. (1985) (3)
- Procyanidin C 1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in the A 549 lung cancer cell line (2013) (3)
- Multi-Pathway Cellular Analysis on Crude Natural Drugs/Herbs from Japanese Kampo Formulations (2015) (3)
- Chemical synthesis of oligoribonucleotides containing vicinal 2'-5' and 3'-5' phosphodiester linkages. (1988) (3)
- Synthesis of 2-Methoxycarbonyl-5-methyl-7-methoxy-8-isopropyltetrahydronaphthalen-1-one and Rearrangement of Isopropyl Group of γ-(5-Isopropyl-4-methoxy-2-methylphenyl)-butyric Acid in Polyphosphoric Acid Cyclization (1969) (3)
- p38 pathway as a key downstream signal of CTGF to regulate metastasis potential in NSCLC. (2016) (3)
- Anti‐inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae on mice (2020) (3)
- Novel products in the reaction of 6-cyanotricyclo[5.5.0.0]dodeca-3,6,9,12-tetraene with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (1990) (3)
- Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells. (2016) (2)
- CARBON‐CARBON BOND FORMATION PROMOTED BY TRANSITION METAL CARBONYLS. 16. REACTION OF α,α′‐DIBROMO KETONES AND IRON CARBONYLS. MECHANISTIC ASPECTS (1978) (2)
- Flavanols and Flavanes from Crinum asiaticum and Their Effects on LPS Signaling Pathway Through the Inhibition of NF-κB Activation (2021) (2)
- Loss of cell wall integrity genes CpxA and MrcB causes flocculation in Escherichia coli. (2020) (2)
- Reductive Dehalogenation of Polyhalo Ketones with Low-valent Metals and Related Reducing Agents (1984) (2)
- A METHOD FOR THE GENERATION OF A SYNTHETIC EQUIVALENT OF UNSUBSTITUTED OXYALLYL VIA THE BROMO KETONE-IRON CARBONYL REACTION, A NEW ROUTE TO THUJAPLICINS (1975) (2)
- Interval- and cycle-dependent combined effect of STING agonist loaded lipid nanoparticles and a PD-1 antibody. (2022) (2)
- Internucleotide-linkage formation via the phosphoramidite method using a carboxylic acid as a promoter. (2004) (2)
- Strategies Useful for the Chemical Synthesis of Oligonucleotides and Related Compounds (2005) (2)
- Characterization of a liver metastatic variant of murine K1735M2 melanoma cells. (2000) (2)
- Preparation of Short Oligonucleotides via the Phosphoramidite Method Using a Tetrazole Promoter in a Catalytic Manner. (1998) (2)
- Marginols A‒H, unprecedented pimarane diterpenoids from Kaempferia marginata and their NO inhibitory activities. (2022) (2)
- An Improved Method for Synthesizing Cyclic Bis(3′-5′)diguanylic Acid (c-di-GMP). (2005) (2)
- NKG2D defines tumor‐reacting effector CD8+ T cells within tumor microenvironment (2021) (2)
- REVISED IAI 01762-06 Version 4 cdi-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia (2007) (2)
- Abnormal ozonolysis of allyl acetates: a structural factor (1973) (2)
- Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice (2019) (2)
- A convenient synthesis of adenylyl-(2'----5')-adenylyl-(2'----5')-adenosine (2-5A core). (1984) (2)
- Chemoselective phosphorylation of N-unblocked nucleosides. (1983) (1)
- A Novel Synthesis of Oligonucleotide—Peptide Conjugates with a Base‐Labile Phosphate Linker Between the Two Components According to the Allyl‐Protected Phosphoramidite Strategy. (2000) (1)
- Effect of Molecular Sieves in the Liquid‐Phase Synthesis of Nucleotides via the Phosphoramidite Method. (2002) (1)
- N-PHENYLIMIDAZOLIUM TRIFLATE AS A HIGHLY EFFECTIVE PROMOTER FOR THE INTERRIBONUCLEOTIDE-BOND FORMATION VIA THE PHOSPHORAMIDITE METHOD (2001) (1)
- Effect of Juzentaihoto/Shi-Quan-Da-Bu-Tang on malignant progression and metastasis of tumor cells (2017) (1)
- A facile synthesis of DNA oligomers with modified backbones via the phosphoramidite method without nucleoside base protection. (1999) (1)
- Allyl and allyloxycarbonyl groups as versatile protecting groups in nucleotide synthesis. (1986) (1)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS. XXIII. SYNTHESIS OF 3(2H)-FURANONES BY THE IRON CARBONYL-PROMOTED CYCLOCOUPLING REACTION OF α,α′-DIBROMO KETONES AND CARBOXAMIDES. A CONVENIENT ROUTE TO MUSCARINES (1977) (1)
- Acridone Derivatives from Atalantia monophyla Inhibited Cancer Cell Proliferation through ERK Pathway (2022) (1)
- Establishment of bioluminescent imaging model using murine T cell lymphoma susceptive to NK cell-dependent immune-surveillance. (2021) (1)
- Practical Synthesis of 2′‐5′‐Linked Oligoadenylates (2‐5A Oligomers). (1992) (1)
- A FACILE SYNTHESIS OF 5′-END SOLID-ANCHORED, 3′-END FREE OLIGODEOXYRIBONUCLEOTIDES VIA THE (5′ → 3′)-ELONGATED PHOSPHORAMIDITE STRATEGY (2001) (1)
- Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants (2022) (1)
- Two-Step Co-and Terpolymerization of Diolefins with Vinyl Monomers by Nickel or Cobalt Catalyst Systems (1969) (1)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS PART 13, A NEW ROUTE TO NEZUKONE (1975) (1)
- A Convenient Method for the Synthesis of N-Free 5′-O-(p,p′-Dimethoxytrityl)-2′-deoxyribonucleosides via the 5′-O-Selective Tritylation of the Parent Substances. (2010) (1)
- A Convenient Way to N-Allyloxycarbonyl Protected Adenosine and Cytidine Derivatives. (1998) (1)
- Erratum: (The Journal of Experimental Medicine (June 20, 2005) 201: 12 (1973-1985)) (2005) (1)
- FACILE NUCLEOSIDE PHOSPHORYLATION VIA HYDROXYL ACTIVATION (1983) (1)
- Anti-Metastatic Effects of Curcumin Analogues in a Mouse Breast Cancer Model (2020) (1)
- Allyloxycarbonyl Group: A Versatile Blocking Group for Nucleotide Synthesis. (1987) (1)
- An efficient synthesis of nucleotides via the phosphoramidite method using a triflic acid salt of an imidazole-related compound as a promoter. (2000) (1)
- A novel hamster model of SARS-CoV-2 respiratory infection using a pseudotyped virus (2021) (1)
- Toward an Ideal Synthesis of Oligonucleotides: Development of a Novel Phosphoramidite Method with High Capability (2002) (1)
- Experimental Models of Cytokines and Cancer Prevention (2007) (1)
- CARBON‐CARBON BOND FORMATION PROMOTED BY TRANSITION METAL CARBONYLS. 17. REACTIONS OF POLYBROMO KETONES WITH 1,3‐DIENES IN THE PRESENCE OF IRON CARBONYLS. NEW 3 + 4 → 7 CYCLOCOUPLING REACTION FORMING 4‐CYCLOHEPTENONES (1978) (1)
- Lac water extract inhibits IFN-γ signaling through JAK2-STAT1-IRF1 axis in human melanoma (2018) (1)
- A SOLID SUPPORT WITH A HYDROXYALLYL LINKER, FULL PARTS OF WHICH ARE POTENTIALLY REUSABLE FOR THE SYNTHESIS OF OLIGONUCLEOTIDES (2005) (1)
- Advances in Organic Synthesis Promoted by Transition Metal Complexes (1982) (1)
- Murine NK Cells IL-21 Induces the Functional Maturation of (2004) (1)
- [Reduction of autofluorescence of in vivo fluorescence imaging by using purified diet]. (2009) (1)
- A ribonucleoside with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase, which universally binds to natural nucleosides. (2006) (1)
- SYNTHESIS OF CARBOCAMPHENILONE (V) AND ITS 6,7-DEHYDRO DERIVATIVE (VI) (1975) (1)
- Chemical Synthesis of Cytidine‐5′‐monophosphono‐N‐acetylneuraminic Acid (CMP‐Neu5Ac) (I). (1993) (1)
- Efficient liquid-phase synthesis of short-length nucleotides via the phosphoramidite method using stoichiometric amounts of reactants. (2001) (1)
- EVIDENCE FOR THE EXISTENCE OF CANCER IMMUNOSURVEILLANCE (2004) (1)
- Effect of Additives on Second-Step Copolymerization of Styrene at High Temperature onto cis-Polybutadiene by Nickel Catalyst Systems (1969) (1)
- Potential of Kampo medicine in cancer immunotherapy (2022) (0)
- A New Synthetic Route to Oligoribonucleotides Based on CpRu-Catalyzed Deallylation. (2007) (0)
- 1,3‐Dibromoacetone (2001) (0)
- NKG2D-Dependent Mechanism IL-21 Enhances Tumor Rejection through a (2013) (0)
- Author Correction: A novel hamster model of SARS-CoV-2 respiratory infection using a pseudotyped virus (2022) (0)
- Activation of the stimulator of interferon genes (STING) adaptor attenuates experimental autoimmune encephalitis (THER6P.848) (2014) (0)
- Imidazolium triflate as an efficient promoter for O-selective phosphitylation of N-unprotected nucleosides via the phosphoramidite approach. (1997) (0)
- A convenient method for the oxidation of nucleoside phosphites to phosphates. (1985) (0)
- Catalytic use of 1 H-tetrazole in condensation nucleoside and a nucleoside phosphoramidite. (1995) (0)
- C-NUCLEOSIDE SYNTHESIS. 17. A STEREOCONTROLLED TOTAL SYNTHESIS OF C-NUCLEOSIDES (1985) (0)
- Preparation of an Artificial Ribonucleoside with Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Base and Its Discriminating Ability for Natural Nucleosides. (2008) (0)
- SYNTHETIC STUDIES ON SPIROVETIVANES PART 2, STEREOSPECIFIC TOTAL SYNTHESIS OF DL‐HINESOL, DL‐ALPHA‐VETISPIRENE AND DL‐BETA‐VETISPIRENE (DL‐BETA‐ISOVETIVENENE) (1974) (0)
- Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H, 3H, 6H, 8H)-tetraone as a novel universal base. (2005) (0)
- [Synthesis of oligodeoxyribonucleotides with modified internucleotide phosphate residues]. (1995) (0)
- Potent Tolerogenic Responses Adaptor in Myeloid Dendritic Cells Induces Cutting Edge: DNA Sensing via the STING (2013) (0)
- 127 The Histologic Evaluation and Treatment of Occlusion of the Tubal Pars Interstitialis : Tubo Uterine Anastomosis (1990) (0)
- Induction by Anti-DR5 Antibody Therapy IL-21 Enhances Tumor-Specific CTL (2006) (0)
- Evaluation of chimeric antigen receptor of humanized rabbit‐derived T cell receptor‐like antibody (2022) (0)
- Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis Is an Important Endogenous Mechanism for Resistance to Liver Metastases in Murine Renal Cancer 1 (2002) (0)
- Organic Synthesis, Chemical Properties, and Biological Activities of Cyclic Bis(3′‐5′) Diguanylic Acid (c‐di‐GMP) and Its Analogues (2006) (0)
- Application of allyloxycarbonyl group as a protecting group to oligodeoxyribonucleotide synthesis. (1988) (0)
- Abstract 6391: Development of a novel strategy for cancer immunotherapy based on tumor immunogenicity improvement by HLA-drug interaction (2023) (0)
- FunctionHomeostasis, Activation, and Antitumor Type I IFN Contributes to NK Cell (2007) (0)
- Nucleobase Protection with Allyloxycarbonyl (2005) (0)
- Cell Vaccination Efficacy Dendritic Cells In Vivo and Limits Dendritic NK Cell TRAIL Eliminates Immature (2003) (0)
- Up-RegulationHomeostasis Is Associated with KLRG1 NK Cell Maturation and Peripheral (2007) (0)
- Up-RegulationIs Associated with KLRG1 NK Cell Maturation and Peripheral (2013) (0)
- Induction of systemic and therapeutic antitumor immunity using intratumoral injection of bone-marrow derived dendritic cells genetically modified to express interleukin 12 combined with anti-CTLA-4 antibody (2015) (0)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS. 26. STEREOCONTROLLED SYNTHESIS OF SHOWDOMYCIN AND 6-AZAPSEUDOURIDINES (1978) (0)
- Anti-Inflammatory and Cytoprotective Effect of Kaempferia galanga Extracts by Targeting NF-κB Activity (2022) (0)
- Correction (2006) (0)
- Two cyanobacterial response regulators with diguanylate cyclase activity, Rre2 and Rre8, participate in biofilm formation. (2023) (0)
- A new phosphorylation method for the nucleotide synthesis. (1982) (0)
- Title Report on the use of non-clinical studies in the regulatoryevaluation of oncology drugs (2019) (0)
- Retraction: Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors (2006) (0)
- Improved Methods for the Preparation of 2′-Deoxyribonucleoside and Ribonucleoside 3′-Phosphoramidites with Allylic Protectors. (2010) (0)
- Synthesis of a peptide nucleic acid oligomer with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase. (2005) (0)
- Activation in Hepatic Injury NKG2A Inhibits Invariant NKT Cell (2008) (0)
- Allyl Protection of Internucleotide Linkage. (1986) (0)
- Functional characterization of multiple PAS domain-containing diguanylate cyclases in Synechocystis sp. PCC 6803. (2020) (0)
- A nonclassical non-V (cid:1) 14J (cid:1) 18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance (2005) (0)
- ABNORMAL OZONOLYSIS OF ALLYL ACETATES, A STRUCTURAL FACTOR (1973) (0)
- Allyl protection of O6 position of 2'-deoxyguanosine. (1990) (0)
- A process for the chemical synthesis of oligonucleotides (1998) (0)
- SYNTH. VON 2‐METHOXYCARBONYL‐5‐METHYL‐7‐METHOXY‐8‐ISOPROPYL‐TETRAHYDRONAPHTHALINON‐(1) UND UMLAGERUNG DER ISOPROPYLGRUPPE VON GAMMA‐(5‐ISOPROPYL‐4‐METHOXY‐2METHYL‐PHENYL)‐BUTTERSAEURE BEI DER CYCLISIERUNG MIT POLYPHOSPHORSAEURE (1970) (0)
- Comparison of two Kampo medicines in a diet‐induced mouse obesity model (2015) (0)
- Costimulatory Pathways Functions of NKT Cells by CD28 and CD40 Differential Regulation of Th1 and Th2 (2001) (0)
- New Synthesis of Troponoid Compounds via the Iron Carbonyl Promoted Cyclocoupling between Polybromo (1978) (0)
- A Facile Method for the Oxidation of Nucleoside H‐Phosphonates to Phosphates with Bis(trimethylsilyl) Peroxide. (2000) (0)
- GSTA4 governs melanoma immune resistance and metastasis. (2022) (0)
- Binding affinity of a peptide nucleic acid containing pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase for oligonucleotides. (2007) (0)
- Solid-Phase Synthesis of Oligodeoxyribonucleotides Using the Bis(trimethylsilyl)peroxide Oxidation of Phosphites. (1987) (0)
- Partial methyl phosphotriester-modification of oligodeoxyribonucleotides. (1992) (0)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS PART 8, IRON CARBONYL PROMOTED REACTION OF ALPHA,ALPHA′-DIBROMO KETONES AND CARBOXAMIDES, A CONVENIENT ROUTE TO MUSCARINES VIA FURANONES (1973) (0)
- Key elements of validation for computerized system in analytical laboratory (SEMINAR: COMPUTERIZED SYSTEMS VALIDATION (FDA21 CFR PART11) ON DRUG DEVELOPMENT) (Proceedings of the 30th Annual Meeting) (2003) (0)
- Title : A new adjuvant delivery system ' cyclic di-GMP / YSK 05 liposome ' for cancer immunotherapy (2018) (0)
- Anti-metastatic function of triterpene phytochemicals from guggul by targeting tumor-intrinsic NF-κB activation in triple-negative breast cancer cells (2022) (0)
- A CONVENIENT SYNTHESIS OF 2′-5′-LINKED OLIGORIBONUCLEOTIDES (1985) (0)
- CD1d-restricted type II NKT cells are sufficient for the down regulation of immunosurveilance against a nonregressor syngeneic colon carcinoma (2006) (0)
- BPB Reports (2020) (0)
- A facile solid-phase synthesis of oligodeoxyribonucleotides and their amino acid conjugates via the allyl-protected phosphoramidite approach with benzimidazolium triflate as a promoter (1999) (0)
- Direct synthesis of solid-anchored DNA oligomers. (1991) (0)
- Impact of Acute Exercise on Natural Killer Cell Subset Distributions in Selected Mouse Tissues: 2505 (2011) (0)
- DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies (2023) (0)
- General, regiocontrolled synthesis of unsymmetrically linked dinucleoside adenosine 2',3'-bis(phosphate)s. (1989) (0)
- CAMSAP3 negatively regulates lung cancer cell invasion and angiogenesis through nucleolin/HIF-1α mRNA complex stabilization. (2023) (0)
- Genome-wide transcriptional profile of Escherichia coli in response to high levels of the second messenger 3′,5′-cyclic diguanylic acid. VOLUME 281 (2006) PAGES 8090-8099 (2007) (0)
- Ethyl P-Methoxycinnamate: An Active Anti-Metastasis Agent and Chemosensitizer Targeting NFκB from Kaempferia galanga for Melanoma Cells (2022) (0)
- Synthesis of phenylphosphonodiester-modified oligodeoxyribonucleotides via the allyl protection. (1993) (0)
- Neuroprotective and anticancer effects of 7-Methoxyheptaphylline via the TAK1 pathway (2022) (0)
- A Facile Synthesis of 5′-End Solid-Anchored, 3′-End Free Oligodeoxyribonucleotides via the (5′3′)-Elongated Phosphoramidite Strategy. (2001) (0)
- Cyclic Di-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia (cid:1) (2007) (0)
- TRAIL‐DR5 interaction by NFkB pathway induces metastatic potential. Lung metastasis of intravenously inoculated B16F10 mouse melanoma cells stimulated without (left panels) or with TRAIL (right panels) was visualized by bioluminescent imaging in mice (2013) (0)
- Chemical Synthesis of Oligoribonucleotides Containing Vicinal 2′-5′ and 3′-5′ Phosphodiester Linkages (1989) (0)
- Verfahren zum Herstellen von regellosen Copolymeren aus konjugierten Dienen und aromatischen Kohlenwasserstoffen A process for preparing random copolymers of conjugated dienes and aromatic hydrocarbons (1968) (0)
- Novel Products in the Reaction of 6-Cyanotricyclo(5.5.0.02,5)dodeca-3,6,9,12-tetraene with 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone. (1990) (0)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS PART 10, A NEW, GENERAL SYNTHESIS OF TROPANE ALKALOIDS (1974) (0)
- [Results of molecular screening of anti-cancer agents. 8. Results of screening of possible anti-cancer agents in Japan]. (2000) (0)
- Utility of Porous Glass with a new long-chain alkylamine spacer arm as a solid support for synthesis of oligodeoxyribonucleotides via the phosphoramidite method. (2002) (0)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS. 27. IRON CARBONYL PROMOTED REACTION OF α,α′-DIBROMO KETONES AND ISOBUTYLENE. AN ENE REACTION INVOLVING ALLYLIC CATIONS (1978) (0)
- Dependent upon Perforin NKG 2 D Receptor-Ligand Interaction Is Cutting Edge : Tumor Rejection Mediated by Raulet and (2002) (0)
- CARBON-CARBON BOND FORMATIONS PROMOTED BY TRANSITION METAL CARBONYLS. 25. A SINGLE-STEP SYNTHESIS OF (.+-.)-α-CUPARENONE (1978) (0)
- Synthesis of 2′-5′,3′-5′ Linked Triadenylates (I). (1987) (0)
- A carcinoma-associated mucin, Muc21/epiglycanin, modulates cell adhesion and survival (2011) (0)
- Various Coupling Agents in the Phosphoramidite Method for Oligonucleotide Synthesis (2018) (0)
- NOVEL CYCLOPENTENONE SYNTHESIS VIA THE IRON CARBONYL AIDED CYCLOCOUPLING BETWEEN α,α′-DIBROMO KETONES AND ENAMINES (1978) (0)
- SYNTHESIS STUDIES ON SPIROVETIVANES PART 1, SPIROCONDENSATION OF A 4-(3′-FORMYLPROPYL)-3-CYCLOHEXENONE AND STEREOSPECIFIC TOTAL SYNTHESIS OF DL-BETA-VETIVONE (1974) (0)
- A CONVENIENT METHOD FOR THE FORMATION OF INTERNUCLEOTIDE LINKAGE (1985) (0)
- Increased Marrow CD57+ Cytotoxic T Cells Is a Powerful Prognostic Marker for Survival in Patients with Relapsed Multiple Myeloma (MM) Receiving Thalidomide. (2005) (0)
- Adjuvant Therapy for Metastatic Cancer Gene-Engineered T Cells as a Superior (2004) (0)
- and Suppressing Molecules by Antibodies Targeting Immune Activating Combination Therapy of Established Tumors (2010) (0)
- Migratory Capacity Subsets with Distinct Responsiveness and CD27 Dissects Mature NK Cells into Two (2017) (0)
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What Schools Are Affiliated With Yoshihiro Hayakawa?
Yoshihiro Hayakawa is affiliated with the following schools: