Yoshihiro Ogawa
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Biology
Yoshihiro Ogawa's Degrees
- PhD Biochemistry University of Tokyo
- Masters Molecular Biology University of Tokyo
- Bachelors Biology University of Tokyo
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(Suggest an Edit or Addition)Yoshihiro Ogawa's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Paracrine Loop Between Adipocytes and Macrophages Aggravates Inflammatory Changes: Role of Free Fatty Acids and Tumor Necrosis Factor α (2005) (1004)
- Role of the Toll-like Receptor 4/NF-&kgr;B Pathway in Saturated Fatty Acid–Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages (2007) (726)
- Adipose tissue macrophages: their role in adipose tissue remodeling (2010) (432)
- Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect. (2003) (300)
- Increased Adiponectin Secretion by Highly Purified Eicosapentaenoic Acid in Rodent Models of Obesity and Human Obese Subjects (2007) (297)
- Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. (2007) (220)
- Leptin-to-adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients. (2004) (214)
- Angiopoietin-related growth factor antagonizes obesity and insulin resistance (2005) (198)
- Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction (2016) (181)
- Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor. (2005) (169)
- Role of CC Chemokine Receptor 2 in Bone Marrow Cells in the Recruitment of Macrophages into Obese Adipose Tissue* (2008) (146)
- Increase in Glucose-6-Phosphate Dehydrogenase in Adipocytes Stimulates Oxidative Stress and Inflammatory Signals (2006) (146)
- Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity (2010) (141)
- Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis (2014) (138)
- Adipose tissue inflammation and ectopic lipid accumulation [Review] (2012) (137)
- Evaluation of the Cardio-Ankle Vascular Index, a New Indicator of Arterial Stiffness Independent of Blood Pressure, in Obesity and Metabolic Syndrome (2008) (134)
- Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. (2011) (126)
- Adipose tissue inflammation and ectopic lipid accumulation. (2012) (120)
- Endothelial PGC-1α mediates vascular dysfunction in diabetes. (2014) (118)
- Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans (2013) (117)
- Activating Transcription Factor 3 Constitutes a Negative Feedback Mechanism That Attenuates Saturated Fatty Acid/Toll-Like Receptor 4 Signaling and Macrophage Activation in Obese Adipose Tissue (2009) (113)
- Unbalanced M1/M2 Phenotype of Peripheral Blood Monocytes in Obese Diabetic Patients (2010) (105)
- Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH (2018) (100)
- In Vivo and In Vitro Inhibition of Monocyte Adhesion to Endothelial Cells and Endothelial Adhesion Molecules by Eicosapentaenoic Acid (2008) (99)
- Role of MAPK Phosphatase-1 in the Induction of Monocyte Chemoattractant Protein-1 during the Course of Adipocyte Hypertrophy* (2007) (99)
- Increased Expression of DNA Methyltransferase 3a in Obese Adipose Tissue: Studies With Transgenic Mice (2010) (89)
- Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome (2009) (83)
- Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages (2013) (82)
- Synthetic “smart gel” provides glucose-responsive insulin delivery in diabetic mice (2017) (82)
- Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans (2011) (76)
- Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor. (2008) (75)
- Adipose Tissue Remodeling as Homeostatic Inflammation (2011) (74)
- fect of Eicosapentaenoic Acid in High-fat/High-sucrose Diet-induced Obesity: Importance of Hepatic Lipogenesis (2010) (71)
- Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages. (2010) (71)
- Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo (2014) (68)
- Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia (2012) (67)
- PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle (2014) (66)
- Role of Central Leptin Signaling in the Starvation-Induced Alteration of B-Cell Development (2011) (58)
- Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α (2015) (57)
- SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo (2014) (57)
- CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis. (2017) (55)
- Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues (2017) (53)
- Intact kinase homology domain of natriuretic peptide receptor-B is essential for skeletal development. (2007) (50)
- Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα (2012) (48)
- Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood (2018) (47)
- Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform‐specific manner (2007) (47)
- Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis (2018) (46)
- Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis (2017) (45)
- The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation (2012) (45)
- Roles for Cell-Cell Adhesion and Contact in Obesity-Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance. (2017) (45)
- A Novel Glycerophosphodiester Phosphodiesterase, GDE5, Controls Skeletal Muscle Development via a Non-enzymatic Mechanism* (2010) (44)
- Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor. (2007) (43)
- The cathepsin L gene is a direct target of FOXO1 in skeletal muscle. (2010) (42)
- Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver (2014) (42)
- Urinary cystatin C as a potential risk marker for cardiovascular disease and chronic kidney disease in patients with obesity and metabolic syndrome. (2011) (42)
- Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver (2012) (39)
- PGC-1α-mediated changes in phospholipid profiles of exercise-trained skeletal muscle[S] (2015) (39)
- Forkhead box class O family member proteins: The biology and pathophysiological roles in diabetes (2017) (38)
- Abstract 19681: Endothelial PGC-1alpha Mediates Vascular Dysfunction in Diabetes (2012) (37)
- Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis–associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects (2020) (37)
- Eicosapentaenoic Acid Ameliorates Non-Alcoholic Steatohepatitis in a Novel Mouse Model Using Melanocortin 4 Receptor-Deficient Mice (2015) (34)
- Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A. (2013) (34)
- An increase in the EPA/AA ratio is associated with improved arterial stiffness in obese patients with dyslipidemia. (2014) (34)
- ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis. (2015) (33)
- A reduced M1-like/M2-like ratio of macrophages in healthy adipose tissue expansion during SGLT2 inhibition (2018) (33)
- Effect of Peroxisome Proliferator‐activated Receptor‐α Ligands in the Interaction Between Adipocytes and Macrophages in Obese Adipose Tissue (2008) (33)
- SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1 (2016) (29)
- Paternal Allele Influences High Fat Diet-Induced Obesity (2014) (28)
- Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor. (2011) (28)
- The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages (2016) (27)
- An α-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients (2006) (27)
- Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration (2017) (24)
- C-type lectin Mincle mediates cell death–triggered inflammation in acute kidney injury (2020) (24)
- Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice (2019) (23)
- Molecular mechanism of obesity‐induced ‘metabolic’ tissue remodeling (2017) (22)
- Glucose-independent persistence of PAI-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium: implication in metabolic memory. (2013) (21)
- Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders. (2020) (20)
- Role of central leptin signaling in renal macrophage infiltration. (2010) (20)
- Efficacy and safety of sitagliptin for the treatment of diabetes mellitus complicated by chronic liver injury (2015) (20)
- Overexpression of FOXO1 in skeletal muscle does not alter longevity in mice (2009) (20)
- Diurnal expression of Dnmt3b mRNA in mouse liver is regulated by feeding and hepatic clockwork (2012) (18)
- An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients. (2006) (18)
- FOXO1 activates glutamine synthetase gene in mouse skeletal muscles through a region downstream of 3'-UTR: possible contribution to ammonia detoxification. (2014) (16)
- Intestine-Targeted DGAT1 Inhibition Improves Obesity and Insulin Resistance without Skin Aberrations in Mice (2014) (16)
- Association Between Body Weight at Weaning and Remodeling in the Subcutaneous Adipose Tissue of Obese Adult Mice With Undernourishment In Utero (2013) (16)
- Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation (2017) (16)
- Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes. (2013) (15)
- Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress (2015) (14)
- Increased Systemic Glucose Tolerance with Increased Muscle Glucose Uptake in Transgenic Mice Overexpressing RXRγ in Skeletal Muscle (2011) (13)
- Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis (2019) (12)
- Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH (2021) (12)
- Possible Involvement of Opa-Interacting Protein 5 in Adipose Proliferation and Obesity (2014) (12)
- The unified hypothesis of interactions among the bone, adipose and vascular systems: 'osteo-lipo-vascular interactions'. (2006) (12)
- Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle (2020) (12)
- A Novel Role for Adipose Ephrin-B1 in Inflammatory Response (2013) (12)
- FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting (2022) (11)
- Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity (2016) (9)
- Integrated network systems and evolutionary developmental endocrinology. (2010) (8)
- Optimization of left adrenal vein sampling in primary aldosteronism: Coping with asymmetrical cortisol secretion. (2017) (8)
- Inflammatory responses increase secretion of MD-1 protein. (2016) (7)
- Fat/Vessel-derived Secretory Protein (Favine)/CCDC3 Is Involved in Lipid Accumulation* (2015) (7)
- Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system (2020) (7)
- Macrophage‐Colony Stimulating Factor in Obese Adipose Tissue: Studies With Heterozygous op/+ Mice (2007) (7)
- Effects of oral health instructions on glycemic control and oral health status of periodontitis patients with type 2 diabetes mellitus: A preliminary observation (2019) (6)
- Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients. (2016) (6)
- Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes (2021) (6)
- Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding (2020) (6)
- HNF1A Mutations and Beta Cell Dysfunction in Diabetes (2022) (6)
- Diabetes Mellitus as Dysfunction of Interactions among all Organs: “Ominous Orchestra of Organs” (2008) (6)
- Homeostatic inflammation, an emerging concept. (2010) (6)
- Response to Comment on: Satoh-Asahara et al. Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia. Diabetes Care 2012;35:2631–2639 (2013) (5)
- The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. (2021) (5)
- Metabolic syndrome and NAFLD/NASH. (2017) (5)
- Macrophages rely on extracellular serine to suppress aberrant cytokine production (2021) (5)
- Chronic inflammation as a molecular basis of nonalcoholic steatohepatitis: role of macrophages and fibroblasts in the liver (2020) (4)
- Plasticity of histone modifications around Cidea and Cidec genes with secondary bile in the amelioration of developmentally-programmed hepatic steatosis (2019) (4)
- A Case of Rathke's Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus (2014) (4)
- [Role of chronic inflammation in adipose tissue in the pathophysiology of obesity]. (2013) (4)
- Insulin‐Induced Ectodomain Shedding of Heparin‐Binding Epidermal Growth Factor‐Like Growth Factor in Adipocytes In Vitro (2010) (2)
- [Obesity: Progress in diagnosis and treatment; Topics, IV. Recent topics; 2. Obesity and inflammation]. (2011) (2)
- Role of chronic inflammation in the pathogenesis of nonalcoholic steatohepatitis: lessons from a unique mouse model using melanocortin receptor-deficient mice. (2021) (2)
- Sialic Acid-Binding Immunoglobulin-Like Lectin1 as a Novel Predictive Biomarker for Relapse in Graves' Disease: A Multicenter Study. (2018) (2)
- FoxO1 inhibits skeletal muscle hypertrophy through mTOR-independent mechanisms (2013) (2)
- Molecular Mechanisms Underlying Obesity-Induced Chronic Inflammation (2016) (1)
- Pathophysiologic Role of Leptin in Cardiovascular Diseases(Adipocytokines and Atherosclerosis, The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (1)
- Pathogenesis of Non-alcoholic Steatohepatitis and Its Potential Therapeutic Strategies (2015) (1)
- [Inflammatory changes in obese adipose tissue]. (2009) (1)
- Vascular complications and coagulation-related changes in the perioperative period in Japanese patients undergoing non-cardiac surgery. (2014) (1)
- Erratum to Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages [Biochem. Biophys. Res. Commun., 398, (2010), 284-289] (2010) (1)
- Role of MAPK phosphatase‑1 (MKP‑1) in the induction of MCP‑1 during the course of adipocyte hypertrophy (2008) (1)
- Parenchymal-stromal cell interaction in metabolic diseases (2015) (1)
- [Obesity and homeostatic inflammation]. (2011) (0)
- [Biological function of leptin and obesity-related diseases]. (2004) (0)
- Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system (2020) (0)
- A case of diabetes mellitus accompanied by tumor-forming pancreatitis that was difficult to distinguish from pancreatic cancer (2017) (0)
- Adipose tissue and chronic inflammation (2011) (0)
- Clinical Implications of Leptin : Insights from Transgenic Skinny Mice (2003) (0)
- Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84 (2020) (0)
- 2. Obesity and Inflammation. (2011) (0)
- [Skeletal muscle function and FOXO]. (2008) (0)
- Molecular Mechanism of Lifestyle-related Diseases : See Both the Wood and Trees! (2016) (0)
- Adipose Tissue Remodeling : an Intimate Crosstalk between Adipocytes and Macrophages(Keynote Lecture, Diabetes/Obesity(basic), The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- 145: A synthetic retinoid, Am80, suppresses IL-6 expression, and inhibits both acute rejection and cardiac allograft vasculopathy in cardiac transplantation (2007) (0)
- [Molecular mechanism of adipose tissue remodeling]. (2011) (0)
- Efficacy of liraglutide in Japanese patients with type 2 diabetes assessed using continuous glucose monitoring (2013) (0)
- [Lifestyle-related diseases and an inter-organ metabolic network]. (2016) (0)
- A case of an elderly woman with concurrent pancreatic cancer and slowly progressive type 1 diabetes mellitus (2017) (0)
- 2. Molecular Mechanism of Metabolic Syndrome (2016) (0)
- Postoperative renal impairment and longitudinal change in renal function after adrenalectomy in patients with Cushing’s syndrome (2020) (0)
- EXPRESSION OF INFLAMMATORY CYTOKINES IN PERICARDIAL AND SUBCUTANEOUS ADIPOSE TISSUE ON CORONARY ARTERY DISEASE (2011) (0)
- Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH (2018) (0)
- Adipose tissue inflammation and ectopic fat accumulation (2012) (0)
- Deficiency of Melanocortin 4 Receptor Promotes Vascular Vulnerability in Mice (2018) (0)
- A reduced M1-like/M2-like ratio of macrophages in healthy adipose tissue expansion during SGLT2 inhibition (2018) (0)
- Acupuncture treatment of entrapment neuropathy of the lower extremity. II. (1990) (0)
- FOXO1 activates glutamine synthetase gene in mouse skeletal muscles (820.10) (2014) (0)
- Chromatin Correction with Secondary Bile Acid is Involved in the Amelioration of Developmentally-Programmed Hepatic Steatosis (2019) (0)
- Amino acid content in blood of PGC-1α Tg mice. (2014) (0)
- The role of adipose-tissue chronic inflammation in the progression of thrombophilia (2015) (0)
- 2009-P: Molecular Mechanisms of Obesity-Associated Vascular Vulnerability via Signals of Appetite Regulation (2019) (0)
- 2) Lifestyle-related Diseases: See Both the Forest and Trees! (2019) (0)
- Clinical studies on acupuncture treatment for stiff shoulder and pains of neck, shoulder and arms, and on the mechanism of pathopoiesis. (1988) (0)
- Role of DNA methylation in the regulation of lipogenic gene expression in the mouse neonatal liver (2012) (0)
- A case of type 1 diabetes with frequent hypoglycemic episodes induced by primary hypothyroidism (2014) (0)
- Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis (2018) (0)
- Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis–associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects (2020) (0)
- Macrophages rely on extracellular serine to suppress aberrant cytokine production (2021) (0)
- Effects of Compound A and Compound B on the triglyceride synthesis. (2014) (0)
- [Pathophysiologic role of macrophages infiltrated into obese adipose tissue]. (2006) (0)
- Pathway map of Val, Leu, and Ile degradation. (2014) (0)
- Adipocytokines and metabolic regulation (2006) (0)
- [113th Scientific Meeting of the Japanese Society of Internal Medicine: Presidential Lecture: Panel Discussion: Molecular Mechanism of Metabolic Syndrome]. (2016) (0)
- Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood (2018) (0)
- Alternative splicing and O-glycosylation are determinants of the susceptibility of ADAM-mediated ectodomain shedding (2016) (0)
- 278: A Series of Cardiopulmonary Exercise Test for LVAS Patients, Which Is Combined with Pump Off-Tests, Effectively Predicts Device Explantability (2008) (0)
- Hydrophobic, inorganic particles containing toner (2004) (0)
- Obesity, diabetes, and gut microbiome (2016) (0)
- Understanding lipid-related orphan G protein-coupled receptors using activating GPCR mutations (2018) (0)
- Difficult medical management in elderly diabetic patients with polypharmacy: An analysis of cases accompanied by frequent consciousness loss and asymptomatic hypoglycemia (2015) (0)
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