Yoshikatsu Kanai

Q: What Schools Are Affiliated With Yoshikatsu Kanai

Yoshikatsu Kanai is affiliated with the following schools: University of Tokyo, Institute of Science Tokyo, Osaka University, Kyorin University, Wakayama Medical University, Kyoto University, Harvard University

Yoshikatsu Kanai's AcademicInfluence.com Rankings

Yoshikatsu Kanai

Computer Science

#5111

World Rank

#5401

Historical Rank

Computational Linguistics

#634

World Rank

#646

Historical Rank

Machine Learning

#1231

World Rank

#1251

Historical Rank

Artificial Intelligence

#1459

World Rank

#1488

Historical Rank

computer-science Degrees

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Computer Science

Yoshikatsu Kanai's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Yoshikatsu Kanai's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate (1996) (2495)
Primary structure and functional characterization of a high-affinity glutamate transporter (1992) (1347)
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels (2002) (1280)
Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)* (1998) (968)
Expression cloning of a mammalian proton-coupled oligopeptide transporter (1994) (856)
CATs and HATs: the SLC7 family of amino acid transporters (2004) (682)
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. (2001) (645)
Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter* (1997) (636)
The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. (1994) (579)
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. (2001) (495)
Cloning and Functional Characterization of a System ASC-like Na+-dependent Neutral Amino Acid Transporter* (1996) (494)
Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain* (1999) (483)
Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity* (1999) (480)
The SLC3 and SLC7 families of amino acid transporters. (2013) (467)
The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects (2004) (439)
Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta* (2000) (394)
Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. (2002) (373)
Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population (2009) (366)
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver (1998) (347)
Identification and characterization of the high-affinity choline transporter (2000) (330)
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. (2008) (324)
Cloning and characterization of the vasopressin-regulated urea transporter (1993) (284)
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (272)
Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities (1999) (261)
The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression. (1994) (258)
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder (2004) (258)
Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids* (2000) (256)
The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier (2000) (245)
A new family of neurotransmitter transporters: the high‐affinity glutamate transporters (1993) (238)
The SLC1 high-affinity glutamate and neutral amino acid transporter family. (2013) (236)
L‐type amino acid transporter 1 as a potential molecular target in human astrocytic tumors (2006) (235)
Expression Cloning of a Na+-independent Aromatic Amino Acid Transporter with Structural Similarity to H+/Monocarboxylate Transporters* (2001) (233)
T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. (1999) (227)
Identification of a Novel System L Amino Acid Transporter Structurally Distinct from Heterodimeric Amino Acid Transporters* (2003) (225)
The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. (2003) (223)
Amino acid transporters revisited: New views in health and disease. (2018) (222)
L‐type amino‐acid transporter 1 as a novel biomarker for high‐grade malignancy in prostate cancer (2009) (218)
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP) (2014) (214)
l‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth (2010) (211)
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. (2004) (204)
Organic anion transporter family: current knowledge. (2006) (203)
Molecular Characteristics of Na+-coupled Glucose Transporters in Adult and Embryonic Rat Kidney * (1995) (201)
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder (2016) (199)
Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I–III nonsmall cell lung cancer (2008) (198)
The elusive transporters with a high affinity for glutamate (1993) (193)
Electrogenic Properties of the Epithelial and Neuronal High Affinity Glutamate Transporter (*) (1995) (186)
Molecular Identification of a Novel Carnitine Transporter Specific to Human Testis (2002) (184)
New insights into renal transport of urate (2007) (183)
The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus* (2004) (179)
Identification of an Amino Acid Transporter Associated with the Cystinuria-related Type II Membrane Glycoprotein* (1999) (178)
The ancillary proteins of HATs: SLC3 family of amino acid transporters (2004) (173)
Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. (1992) (169)
Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney. (1999) (167)
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. (1999) (164)
A New Member of the HCO 3 − Transporter Superfamily Is an Apical Anion Exchanger of β-Intercalated Cells in the Kidney* (2001) (154)
Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. (2001) (154)
Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters (2011) (149)
Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. (2002) (149)
Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. (2001) (148)
Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells (2013) (146)
Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications. (1997) (142)
Expression of a system L neutral amino acid transporter at the blood–brain barrier (2000) (141)
l‐type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms (2008) (141)
Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes (2015) (139)
Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer (2012) (137)
Regulation of placental amino acid transporter activity by mammalian target of rapamycin. (2009) (136)
Correlation of L‐type amino acid transporter 1 and CD98 expression with triple negative breast cancer prognosis (2012) (134)
The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. (1999) (131)
The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport. (1994) (131)
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. (2002) (130)
Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis (2006) (130)
Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer. (2010) (126)
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. (2000) (123)
The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes. (1992) (120)
Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells. (2008) (119)
Tissue specific variants of glutamate transporter GLT‐1 (1997) (118)
BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. (2008) (116)
Neuronal high-affinity glutamate transport in the rat central nervous system. (1995) (115)
Mammalian ion‐coupled solute transporters. (1995) (114)
Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon (2014) (113)
Identification of a Novel Voltage-driven Organic Anion Transporter Present at Apical Membrane of Renal Proximal Tubule* (2003) (113)
Transport of 3-Fluoro-l-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET (2012) (112)
Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports d-serine with high affinity (2000) (111)
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout (2013) (110)
Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer (2014) (109)
Novel liver‐specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate (2007) (108)
Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine. (1998) (106)
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. (2005) (105)
ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer (2014) (104)
Fluorine-18-α-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer: A Clinicopathologic Study (2007) (104)
Transport of ochratoxin A by renal multispecific organic anion transporter 1. (1998) (104)
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. (1999) (98)
Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth (2015) (91)
Transport Properties of a System y+L Neutral and Basic Amino Acid Transporter (2000) (90)
Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2 (2015) (89)
The SLC 3 and SLC 7 families of amino acid transporters q (2013) (88)
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. (1999) (88)
Chronic maternal infusion of full‐length adiponectin in pregnant mice down‐regulates placental amino acid transporter activity and expression and decreases fetal growth (2012) (85)
Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules (2005) (84)
Identification and Characterization of a Novel Member of the Heterodimeric Amino Acid Transporter Family Presumed to be Associated with an Unknown Heavy Chain* (2001) (84)
Transient upregulation of the glial glutamate transporter GLAST in response to fibroblast growth factor, insulin-like growth factor and epidermal growth factor in cultured astrocytes. (2001) (81)
Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (81)
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc (2019) (80)
Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma. (2009) (79)
Expression cloning using Xenopus laevis oocytes. (1998) (79)
Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity. (2003) (78)
Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer (2013) (78)
Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions. (2004) (78)
System l-amino acid transporters are differently expressed in rat astrocyte and C6 glioma cells (2004) (77)
Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract (2007) (75)
CD98 Expression Is Associated with Poor Prognosis in Resected Non-Small-Cell Lung Cancer with Lymph Node Metastases (2009) (75)
Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. (1997) (73)
Identification of a Novel Na+-independent Acidic Amino Acid Transporter with Structural Similarity to the Member of a Heterodimeric Amino Acid Transporter Family Associated with Unknown Heavy Chains* (2002) (73)
Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation. (2001) (72)
Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid. (2008) (72)
ABCG2 is a High-Capacity Urate Transporter and its Genetic Impairment Increases Serum Uric Acid Levels in Humans (2011) (71)
Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells. (2017) (70)
The small SLC43 family: facilitator system l amino acid transporters and the orphan EEG1. (2013) (69)
High affinity d- and l-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices (2004) (68)
Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters. (2008) (68)
Corrigendum: Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals (2016) (68)
Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout (2009) (67)
Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1 (2016) (67)
Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. (2002) (67)
Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells. (2008) (66)
LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. (2011) (65)
Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2. (2016) (63)
Expression of L‐type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models (2001) (62)
Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung. (2008) (62)
Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties (2012) (62)
Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule. (1992) (60)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters (2021) (59)
Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney. (2000) (59)
Structure, regulation and physiological roles of urea transporters. (1996) (58)
Correlation of angiogenesis with 18F‐FMT and 18F‐FDG uptake in non‐small cell lung cancer (2009) (58)
L‐type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non‐small cell lung cancer (2009) (56)
Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: potential role in dicarboxylic aminoaciduria and neurodegenerative disorders. (1994) (56)
NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain‐of‐Function Variant Decreases the Risk of Renal Underexcretion Gout (2015) (55)
Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features (2016) (55)
Expression and functional characterisation of System L amino acid transporters in the human term placenta (2015) (55)
System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line. (2009) (54)
JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells. (2014) (54)
Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3. (2006) (54)
Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanoma (2015) (53)
Expression of L-type amino acid transporter 1 (LAT1) as a prognostic and therapeutic indicator in multiple myeloma (2014) (52)
Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions. (2004) (51)
Prognostic significance of L‐type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung (2009) (50)
High expression of L-type amino acid transporter 1 in infiltrating glioma cells (2005) (50)
Expression of amino acid transporters (LAT1, ASCT2 and xCT) as clinical significance in hepatocellular carcinoma (2015) (49)
18F-FMT Uptake Seen Within Primary Cancer on PET Helps Predict Outcome of Non–Small Cell Lung Cancer (2009) (49)
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. (2004) (49)
LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung (2006) (48)
Simultaneous determination of amino-α-carbolines and amino-γ-carbolines in cigarette smoke condensate by high-performance liquid chromatography (1990) (48)
Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1). (2017) (47)
The RNA interference of amino acid transporter LAT1 inhibits the growth of KB human oral cancer cells. (2006) (46)
Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells. (2016) (46)
Detection of carcinogenic glutamic acid pyrolysis products in cigarette smoke condensate. (1990) (44)
Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule (2005) (44)
Integrated physiology of proximal tubular organic anion transport (2005) (44)
Lysophosphatidylcholine Enhances Cytokine Production of Endothelial Cells via Induction of L-Type Amino Acid Transporter 1 and Cell Surface Antigen 4F2 (2004) (43)
Human cystinuria-related transporter: localization and functional characterization. (2001) (42)
Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals (2015) (42)
Novel Liver-specific Organic Anion Transporter OAT7 that Operates the Exchange of Sulfate Conjugates for Short Chain Fatty Acid Butyrate. (2008) (42)
The High-Affinity Glutamate Transporter Family (1997) (42)
Evaluation of thoracic tumors with 18F‐FMT and 18F‐FDG PET‐CT: A clinicopathological study (2009) (42)
Detection of carcinogenic amino-α-carbolines and amino-γ-carbolines in diesel-exhaust particles (1991) (41)
Protein characterization of NA+-independent system L amino acid transporter 3 in mice: a potential role in supply of branched-chain amino acids under nutrient starvation. (2007) (41)
18F-FBPA as a tumor-specific probe of L-type amino acid transporter 1 (LAT1): a comparison study with 18F-FDG and 11C-Methionine PET (2017) (40)
L‐type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas (2009) (40)
L-type amino acid transporter 1 expression is highly correlated with Gleason score in prostate cancer. (2013) (40)
Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma (2016) (39)
The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity. (2006) (39)
Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics. (2021) (38)
A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules* (2010) (38)
Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell Carcinoma (2015) (38)
L-type amino acid transporter 1 (LAT1) expression in malignant pleural mesothelioma. (2011) (37)
Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells. (2005) (37)
Structure–activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling (2016) (37)
A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter. (2006) (37)
Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors. (2015) (36)
Receptor for activated C‐kinase 1 regulates the cellular localization and function of ABCB4 (2009) (36)
Clinicopathological significance of ASC amino acid transporter‐2 expression in pancreatic ductal carcinoma (2015) (35)
Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease. (2017) (35)
Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2) (2011) (35)
A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility (2013) (35)
Functional and Immunochemical Characterization of a Novel Organic Anion Transporter Oat8 (Slc22a9) in Rat Renal Collecting Duct (2008) (34)
Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application (2020) (34)
Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc (2017) (34)
Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue (2017) (34)
Diagnostic usefulness of 18F-FAMT PET and L-type amino acid transporter 1 (LAT1) expression in oral squamous cell carcinoma (2013) (33)
Identification of ABCG2 Dysfunction as a Major Factor Contributing to Gout (2011) (31)
Amino acid transporter LAT3 is required for podocyte development and function. (2009) (31)
Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma (2016) (30)
Properties of L-Type Amino Acid Transporter 1 in Epidermal Ovarian Cancer (2010) (30)
Specific transport of 3‐fluoro‐l‐α‐methyl‐tyrosine by LAT1 explains its specificity to malignant tumors in imaging (2016) (30)
Comparison of L-type amino acid transporter 1 expression and L-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer. (2010) (30)
CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii (2019) (29)
Characterization of 3-[125I]iodo-alpha-methyl-L-tyrosine transport via human L-type amino acid transporter 1. (2003) (29)
Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma (2018) (29)
Expression and functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells. (2004) (29)
Accumulation of 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole and 2-aminodipyrido[1,2-a:3',2'-d]imidazole, carcinogenic glutamic acid pyrolysis products, in plasma of patients with uremia. (1987) (29)
Isoform selectivity of 3-125I-iodo-alpha-methyl-L-tyrosine membrane transport in human L-type amino acid transporters. (2003) (28)
Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate (2017) (28)
Annexin A4‐conferred platinum resistance is mediated by the copper transporter ATP7A (2014) (28)
Mouse organic anion transporter 2 (mOat2) mediates the transport of short chain fatty acid propionate. (2008) (28)
Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma (2020) (27)
Expression of amino acid transporter (LAT1 and 4F2hc) in pulmonary pleomorphic carcinoma. (2019) (27)
Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in surgically resectable stage III non-small cell lung cancer. (2010) (27)
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation (2020) (26)
L-glutamate enhances methylmercury toxicity by synergistically increasing oxidative stress. (2008) (26)
Inhibition of L-type amino acid transporter modulates the expression of cell cycle regulatory factors in KB oral cancer cells. (2010) (26)
A Seven-Transmembrane Receptor That Mediates Avoidance Response to Dihydrocaffeic Acid, a Water-Soluble Repellent in Caenorhabditis elegans (2011) (26)
Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells. (2006) (26)
CD98 as a novel prognostic indicator for patients with stage III/IV hypopharyngeal squamous cell carcinoma (2015) (25)
Biological significance of fluorine-18-α-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer (2014) (25)
JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells (2017) (25)
A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter. (2009) (25)
Clinical significance of coexpression of L-type amino acid transporter 1 (LAT1) and ASC amino acid transporter 2 (ASCT2) in lung adenocarcinoma. (2015) (25)
Targeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice (2020) (24)
Involvement of rBAT in Na(+)-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA. (2000) (24)
The Membrane-Spanning Domain of CD98 Heavy Chain Promotes αvβ3 Integrin Signals in Human Extravillous Trophoblasts (2008) (24)
L-type amino-acid transporter 1 expression predicts the response to preoperative hyperthermo-chemoradiotherapy for advanced rectal cancer. (2010) (24)
A Pathogenic C Terminus-truncated Polycystin-2 Mutant Enhances Receptor-activated Ca2+ Entry via Association with TRPC3 and TRPC7* (2009) (24)
Nicotine induces dendritic spine remodeling in cultured hippocampal neurons (2014) (23)
Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea (2015) (22)
Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer (2017) (22)
Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo. (2010) (21)
L‐type amino acid transporter‐1 and CD98 expression in bone and soft tissue tumors (2015) (21)
L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa. (2007) (21)
Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway. (2007) (21)
Posttranslational regulation of Abcc2 expression by SUMOylation system. (2009) (21)
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer (2020) (21)
Relationship between LAT1 expression and response to platinum-based chemotherapy in non-small cell lung cancer patients with postoperative recurrence. (2011) (20)
Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer. (2015) (20)
Expression of a rabbit renal ascorbic acid transporter in Xenopus laevis oocytes. (1994) (20)
Role of Amino Acid Transporter Expression as a Prognostic Marker in Patients With Surgically Resected Colorectal Cancer (2019) (19)
Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene. (2006) (19)
In vitro and in vivo N-acetylation of carcinogenic glutamic acid pyrolysis products in humans. (1988) (18)
The 4 F 2 hc / LAT 1 complex transports L-DOPA across the blood – brain barrier (2000) (18)
Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons (2012) (18)
α‐Emitting cancer therapy using 211At‐AAMT targeting LAT1 (2020) (18)
Development of a Widely Usable Amino Acid Tracer: 76Br-α-Methyl-Phenylalanine for Tumor PET Imaging (2015) (17)
Biological evaluation of 3-[18F]fluoro-α-methyl-d-tyrosine (d-[18F]FAMT) as a novel amino acid tracer for positron emission tomography (2013) (17)
Nicergoline enhances glutamate uptake via glutamate transporters in rat cortical synaptosomes. (2004) (17)
Spermatogenesis in aged rats after prenatal 3,3',4,4',5-pentachlorobiphenyl exposure. (2007) (16)
Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter. (2019) (16)
CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl. (2005) (16)
The role of CD98 in astrocytic neoplasms (2002) (16)
Amino acid transporters: molecular structure and physiological roles. (2000) (16)
Core-fucosylation plays a pivotal role in hepatitis B pseudo virus infection: a possible implication for HBV glycotherapy. (2016) (16)
Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. (1998) (15)
Carcinogenic glutamic acid pyrolysis product in the dialysate of uremic patients treated by continuous ambulatory peritoneal dialysis. (1988) (15)
Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography. (2016) (14)
Clinicopathological Significance of L-type Amino Acid Transporter 1 (LAT1) Expression in Patients with Adenoid Cystic Carcinoma (2013) (14)
The membrane-spanning domain of CD98 heavy chain promotes alpha(v)beta3 integrin signals in human extravillous trophoblasts. (2008) (14)
Exposure level monitor of 3‐amino‐1,4‐dimethyl‐5H‐pyrido[4, 3‐b]indole, a dietary carcinogen, in rabbits (1989) (13)
CD98 is a promising prognostic biomarker in biliary tract cancer. (2014) (13)
Amino acid sequences of glycopeptides obtained from basic proline-rich glycoprotein of human parotid saliva. (1983) (13)
Carcinogenic Tryptophan Pyrolysis Products Potent Inhibitors of Type A Monoamine Oxidase and the Platelet Response to 5-Hydroxytryptamine (1988) (13)
Detection of carcinogenic glutamic acid pyrolysis products in worcestershire sauce by high‐performance liquid chromatography (1988) (12)
Prognostic impact of LAT1 and CD98 expression in cutaneous angiosarcoma. (2017) (12)
The High-Affinity Glutamate Transporter Family: Structure, Function, and Physiological Relevance (1996) (11)
LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation (2020) (11)
Primary structure of cat osteocalcin. (1984) (11)
Gene expression profiles in t24 human bladder carcinoma cells by inhibiting an l-type amino acid transporter, lat1 (2007) (11)
[Glucose transport in the kidney]. (1997) (11)
Antagonism of gamma-aminobutyric acidA receptor-mediated responses by amino-gamma-carbolines. (1990) (11)
Presence of carcinogenic glutamic-acid pyrolysis products in human cataractous lens. (1988) (10)
Identification of a new family of proteins involved in amino acid transport. (1993) (10)
Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells. (2008) (10)
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2 (2019) (10)
Inhibitory effects of tryptophan pyrolysis products on human platelet aggregation through inhibition of prostaglandin endoperoxide synthetase. (1987) (9)
Receptor for Activated C-Kinase 1 Regulates the Cell Surface Expression and Function of ATP Binding Cassette G2 (2010) (9)
Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model (2020) (9)
Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor (2020) (9)
Prognostic Significance of the Expression of CD98 (4F2hc) in Gastric Cancer. (2017) (9)
Sequential increases in 4F2hc expression during DMBA-induced hamster buccal pouch carcinogenesis. (2003) (8)
NRFL-1, the C. elegans NHERF Orthologue, Interacts with Amino Acid Transporter 6 (AAT-6) for Age-Dependent Maintenance of AAT-6 on the Membrane (2012) (8)
Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex (2018) (8)
JPH 203 , an L-Type Amino Acid Transporter 1 – Selective Compound , Induces Apoptosis of YD-38 Human Oral Cancer Cells (2014) (8)
The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2 (2021) (8)
Time Course of Expression of 7,12-Dimethylbenz[a]anthracene-induced CYP1A1 and CYP1B1 mRNA and Protein in Rat Liver (2003) (7)
Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor (2021) (7)
Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer (2021) (7)
Clinical Significance and Phenotype of MTA1 Expression in Esophageal Squamous Cell Carcinoma. (2017) (7)
[Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters]. (2008) (7)
Detection of carcinogenic amino-alpha-carbolines and amino-gamma-carbolines in diesel-exhaust particles. (1991) (7)
Expression of a human NPT1/SLC17A1 missense variant which increases urate export (2016) (7)
Significance of System L Amino Acid Transporter 1 (LAT-1) and 4F2 Heavy Chain (4F2hc) Expression in Human Developing Intestines (2009) (7)
Identification of a Hypouricemia Patient with SLC2A9 R380W, A Pathogenic Mutation for Renal Hypouricemia Type 2 (2014) (7)
Relationship between CD 147 and expression of amino acid transporters ( LAT 1 and ASCT 2 ) in patients with pancreatic cancer (2015) (6)
Simple But Efficacious Enrichment of Integral Membrane Proteins and Their Interactions for In-Depth Membrane Proteomics (2022) (6)
1 A novel transporter of SLC 22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules (2010) (6)
Transportsomes and channelsomes: Are they functional units for physiological responses? (2011) (6)
Molecular biology of multispecific organic anion transporter family (OAT family) (1999) (6)
Measurement of glutamate uptake and reversed transport by rat synaptosome transporters. (2004) (6)
Pharmaco‐toxicological aspects of carcinogenic tryptophan pyrolysis products in the environment (1991) (6)
Testicular Toxicology of Pubescent and Adult Rats Prenatally Exposure to 3,3',4,4',5-Pentachlorobiphenyl (2007) (6)
Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans (2017) (6)
Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain (2022) (5)
A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy (2020) (5)
[Amino acid transporter molecule as a drug target]. (1999) (5)
Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (5)
Initial Changes of Hepatic Glycogen Granules and Glycogen Phosphorylase a After Exposure to 7,12-dimethylbenz[a]anthracene in Rats (2003) (5)
[Amino acid transporters in cancer]. (2014) (5)
Developing selective L-Amino Acid Transport 1 (LAT1) inhibitors: A Structure-Activity Relationship overview (2019) (5)
Substrate binding sites of glutamate transporters and structurally related neutral amino acid transporters. (1997) (4)
Suppression of GABA-induced chloride current by 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2). (1989) (4)
Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture. (2006) (4)
Expression of LAT1 and 4F2hc in Gastroenteropancreatic Neuroendocrine Neoplasms (2021) (4)
Glucocorticoid mediates the transcription of OAT-PG, a kidney-specific prostaglandin transporter (2014) (4)
Simultaneous determination of amino-alpha-carbolines and amino-gamma-carbolines in cigarette smoke condensate by high-performance liquid chromatography. (1990) (4)
Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma. (2017) (3)
Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes (2020) (3)
[Na+ -dependent amino acid transporters: their structure and function]. (1996) (3)
[Urate transporter and renal hypouricemia]. (2003) (3)
Decreased Expression of a Novel Prostaglandin Transporter, OAT-PG, Facilitates Renocortical PGE2 Accumulation during Rat Pregnancy (2013) (2)
Characterization of Human Orgnic Anion Transporter 4 (hOAT4) as a Low Affinity p-aminohippurate (PAH) Transporter (2007) (2)
Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2 (2022) (2)
Structural insights into human excitatory amino acid transporter EAAT2 (2021) (2)
The voltage‐driven organic anion transport of type I sodium‐phosphate cotransporter and OATv1 (2006) (2)
Detection of N-acetyl derivative of 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1) in Glu-P-1-injected rats. (1988) (2)
Mouse Asc-1 (asc-type amino acid transporter 1) maps to chromosome 7, region B1-B5 (2004) (2)
A novel Na(+)-dependent amino acid transporter with a high affinity to glutamine. (1997) (2)
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells (2022) (2)
The High-Affinity Glutamate and Neutral Amino-Acid Transporter Family Structure, Function, and Physiological Relevance (2013) (2)
Expression cloning and characterization of the glutamate transporter in neurons. (1994) (2)
N-Methyl-beta-carboline-3-carboxamide (FG 7142): An anxiogenic agent in cigarette smoke condensate and its mechanism of formation. (1995) (2)
Evaluation of D-isomer of 18F-FBPA for oncology PET focusing on the differentiation of glioma and inflammation. (2020) (2)
Functional Coupling of a Urate-Anion Exchanger URAT1 and Sodium-Dependent Anion Transporter SMCT2 on a PDZK1 Scaffold; Proposal of “Transportsome” for Urate-Transport (2014) (1)
Preferential Expression of L‐type Amino Acid Transporter 1 in Ameloblasts During Rat Tooth Development (2004) (1)
Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10. (2022) (1)
Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. (1997) (1)
Increased expression of the amino acid transporter LAT1 during healing of acetic acid-induced chronic gastric ulcers in rats (2006) (1)
Structural changes induced by ligand binding drastically increase the thermostability of the Ser/Thr protein kinase TpkD from Thermus thermophilus HB8 (2020) (1)
First in human dosimetry of 18F-NKO-035: a new PET probe targeting L-type amino acid transporter 1 (LAT1) (2020) (1)
Tmem174, a regulator of phosphate transporter prevents hyperphosphatemia (2022) (1)
High affinity D- and L-serine transporter Asc-1: Cloning and dendritic localization in the rat brain. (2004) (1)
Urinary excretion levels of carcinogenic glutamic acid pyrolysis products and their N-acetyl derivatives in humans. (1991) (1)
Differential expression of system L amino acid transporters during wound healing process in the skin of young and old rats. (2008) (1)
Identification and functional characterization of a novel cationic amino acid transporter CAT5 specifically expressed in placenta (2006) (0)
Relationship between the dynamic profile of LAT1 probe and tumoral blood flow: comparison study using 18F-FBPA, 18F-FAMT, and 15O-water PET (2016) (0)
Structure–activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling (2016) (0)
Glucocorticoid mediates the transcription of OAT-PG, a kidney-specific prostaglandin transporter (2013) (0)
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc (2019) (0)
Correction: LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice (2023) (0)
18F-FBPA and 18F-FAMT dynamic PET profile: evaluation of usefulness in differentiating malignant tumors from inflammatory lesions. (2015) (0)
Molecular Mechanisms of Permeation of Methylmercury through the Blood-Tissue Barriers (2000) (0)
Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer (2022) (0)
Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans (2017) (0)
SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
L-FBPA showed higher selectivity for L-type amino acid transporter 1: in vitro cellular uptake analysis compared to L-Methionine. (2016) (0)
LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice (2023) (0)
Comparative phosphoproteomics between non-competitive and competitive inhibitions of L-type amino acid transporter 1 in cancer cells. (2019) (0)
LAT1 plays a critical role in cell proliferation via CDK1 and CDK2 in cabazitaxel-resistant prostate cancer cells (2022) (0)
Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer (2013) (0)
Endothelial-specific Ablation of Non-nuclear Estrogen Receptor alpha Signaling Deteriorates Vascular Remodelling Response (2020) (0)
Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate (2017) (0)
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation (2020) (0)
Radio synthesis and basic evaluation of [18F] NKO 028 as a L-type amino acid transporter 1 (LAT1) PET tracer for cancer diagnosis. (2016) (0)
Cloning and characterization of a transporter for monoamine precursors: The system L amino acid transporter (1998) (0)
Evaluation of testicular toxicology in puberty to adult rats with prenatal exposure for 3, 3', 4, 4', 5-pentachlorobiphenyl(Proceedings of the 32nd Annual Meeting) (2005) (0)
Organic anion transporter 4 (OAT4) interacts with two PDZ Domain Proteins (2005) (0)
[Molecular mechanisms of glucose transport in renal proximal tubules]. (2002) (0)
Regulation of organic anion transporters by PDZ proteins (2006) (0)
L-TYPE AMINO ACID TRANSPORTER 1 EXPRESSION IN PROSTATE CANCER: ASSOCIATION WITH CANCER PROGRESSION AND HIGH-GRADE MALIGNANCY (2008) (0)
New aspects of organic anion transporters in renal tubular epithelium (2007) (0)
[Amino acid composition of gamma-carboxyglutamic acid-containing proteins in the teeth of cats]. (1983) (0)
Neutral amino acids transporter and corresponding gen (1999) (0)
Investigation of novel anti-cancer drug using by alpha-Particle Emitting Radionuclides (2017) (0)
The A BC o f S olute C arriers (2004) (0)
[Significance of nickel analysis in clinical tests]. (1989) (0)
Increased expression of an amino acid transporter LAT1 in healing of acetic acid-induced chronic gastric ulcer in rats (2001) (0)
Induction of rat hepatic CYP 1A1, 1B1, and AhR by 7, 12-dimethylbenz[α]anthracene on prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Drug metabolism, Proceedings of the 32nd Annual Meeting) (2005) (0)
Structure activity relations of aromatic amino acid derivatives to interact with organic anion transporter OAT1 reveal critical moieties for renal accumulation of tumor imaging probes (2018) (0)
Inhibition of amino acid transporter LAT1 drastically suppresses the transport of large neutral amino acids and induces the downregulation of global translation in cancer cells (2022) (0)
21D-02-2 Involvement of Organic Anion Transporter1 (OAT1) in the Development of Renal Toxicity Related to Anionic Substances. (1999) (0)
C-17 IDENTIFICATION OF A NOVEL LIVER SPECIFIC ORGANIC ANION TRANSPORTER SELECTIVE FOR CONJUGATED DRUGS AND STEROID HORMONES (2003) (0)
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1 (2022) (0)
Expression of a system L amino acid transporter at testis of rats after prenatal exposure to di(n-butyl)phate(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting) (2005) (0)
Functional properties and distribution of expression of neutral amino acid transporters in the central nervous system (1997) (0)
[Broad scope amino acid transporters: LAT family]. (2001) (0)
Isoform Selectivity of 3125 I-Iodo-- Methyl-L-Tyrosine Membrane Transport in Human L-Type Amino Acid Transporters (2003) (0)
Transporter inhibitors: from target identification and pharmacology to clinical development (2020) (0)
2SB03 Mechanisms of apical and basolateral sorting of heterodimeric amino acid transporters (2004) (0)
Transport of Methylmercury through the Epithelial Type Amino Acid Transporter System B0 (2019) (0)
A specific PET tracer for L-type amino acid transporter 1 (LAT1) differentiates the function of transporter in tumors from that in inflammatory lesions (2019) (0)
Comprehensive protein analysis of the transport system in a connective tissue of the inner ear (2018) (0)
P-22 Protective effects of N-acetylcysteine, a precursor of glutathione, on teratogenicity of cadmium chloride in mice.(Proceedings of the 27th Annual Meeting) (2000) (0)
SGLT2 inhibitors: anti-diabetic drug discovery based on transporter inhibition (2016) (0)
Expression of Neutral Amino Acid Transporter(LAT1 / 4F2hc)in the Morphogenesis of Human Fetal Development (1999) (0)
Nouvel anticorps anti-cd98 (2007) (0)
S13-5 Significance of LAT1/4F2hc complex in the progression of clear cell renal cell carcinoma (2004) (0)
Membrane-anchored ratiometric fluorescent probe forvisualizing the extracellular juxtamembrane pH (2019) (0)
Critical moieties of aromatic amino acid probes causing renal accumulation in tumor imaging (2020) (0)
Transport of nicotinate by human organic anion transporters of SLC22 family (2006) (0)
First in human and investigator-initiated clinical trial of an anticancer drug targeted on a new amino acid transporter (2021) (0)
Targeted alpha therapy using astatine (211At)-labeled phenylalanine: a preclinical study in glioma xenograft mice (2020) (0)
Correction: A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy (2021) (0)
The role of amino acid transporters in the cytotoxicity of methylmercury.(GENERAL SESSION BY POSTER PRESENTATION)(ENVIRONMENTAL CHEMICALS,HEAVY METALS & CYTOTOXICITY) (2002) (0)
Pharmacology of amino acid transporter LAT1 (SLC7A5): Roles in pathogenesis and the drug discovery targeting LAT1 (2022) (0)
Functional analysis of the acetyl-CoA transporter in Caenorhabditis elegans (2016) (0)
Investigator-initiated clinical trial of an anti-cancer drug targeted on LAT1 (2020) (0)
A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility (2013) (0)
Investigation of expression of a system L neutral amino acid transporter LAT1 and its biological role in human glioma cells (2004) (0)
PCR cloning of Na+-dependent L-alanine transporter SNAT2(ASCT2B) gene from rat kidney. (1996) (0)
[Cell surface pH imaging using poly(ethylene glycol)-phospholipid: its potential as the core structure of membrane anchored-probes]. (2019) (0)
Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma (2020) (0)
Essential roles of LAT1, L-type amino acid transporter 1, in the development of placental syncytiotrophoblast: Importance in cell fusion via the presentation of fusion regulatory protein 4F2hc (2016) (0)
L-Τype Amino Acid Transporter 1 ( LAT 1 ) Expression in Malignant Pleural Mesothelioma (2011) (0)
Functional characterization and tissue localization of a novel liver‐specific organic anion transporter OAT7 (2006) (0)
The multivalent PDZ domain protein PDZK1 upregulates the transport activity of renal urate-anion exchanger URAT1 via its C-terminal (2004) (0)
Anti-tumor effects of L-type amino acid transporter 1 (LAT1) inhibitor in a syngeneic and orthotropic mouse model for melanoma (2019) (0)
Tissue distribution and intrarenal localization of IKEPP/NHERF4 of a member of the NHERF family (2007) (0)
Effects of cephaloridine (CER) on mouse terminal proximal straight tubule (S_3) cell lines expressing rat and human organic anion transporter-1 (OAT1) (1998) (0)
L-type amino acid transporter 1 (LAT1) in endothelial cells of tumor vessels contributes to tumor angiogenesis (2018) (0)
S1-4 Molecular Mechanisms of Permeation of Methylmercury through the Blood-Tissue Barriers.(Proceedings of the 27th Annual Meeting) (2000) (0)
Molecular identification of a novel prostaglandin‐specific organic anion transporter (OAT‐PG) that is colocalized with prostaglandin producing enzyme Cox‐2 in the distal tubular cells. (2006) (0)
Studies on the Incompatibility between Bulbus fritillariae and Radix aconiti praeparata Based on the P-gp (2021) (0)
[Molecular mechanism in biological transport in the kidney: Organic cation/anion transporters]. (2006) (0)
[Amino acid composition of osteocalcin in the maxillary bone of cats]. (1983) (0)
Suppression of colorectal cancer cell growth by combinational inhibition of amino acids transporters (2019) (0)
Cell surface pH imaging using a membrane-anchored ratiometric fluorescence probe: Poly(ethylene glycol)-phospholipid as membrane anchor to investigate the juxtamembrane environment (2019) (0)
"Mutations in SLC6A19 are associated with the Hartnup disorder", 54th Annual Meeting Abstracts (2004) (0)
Contribution of LAT1 to amino acid uptake in cancer cells and suppression of cellular protein synthesis by LAT1 inhibitor (2022) (0)
Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. (2022) (0)
Establishment of novel targeted alpha-radionuclide medicine (2019) (0)
PEPT1-targeted boron delivery for boron neutron capture therapy using BPA-containing dipeptide (2019) (0)
P7-56 Identification of novel system L transporters and their methyl mercury-cysteine conjugates transport properties(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting) (2004) (0)
Characterization of The Expression of The Heavy Chain of 4F2 Antigen As a Therapeutic Target in Prostate Cancer (2020) (0)
Suppression of tumor angiogenesis by inhibition of LAT1 in stromal endothelial cells (2019) (0)
Suppressive effects of LAT1 specific inhibitor on allergic skin inflammation (2019) (0)
BPA-dipeptides, novel boron delivery agents for boron neutron capture therapy, are transported by oligopeptide transporter (2018) (0)
The necessity of pharmacology-pathology collaboration in drug discovery research: from the standpoint of pharmacology (2022) (0)
Cancer drug delivery targeting amino acid transporters (2012) (0)
1126: A New Classification of Phenotype-Genotype of Cystinuria Patients in Japan (2004) (0)
Kidney-specific urate transporter and its gen (2002) (0)
Organic anion transporter (OAT) family: the role as a drug transporter family (2000) (0)
Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation. (2021) (0)
Expression of Amino Acid Transporters in Cancers and Their Application to Cancer Diagnosis and Therapuitics (2008) (0)
The role of heterodimeric transporters in cancer cell growth (2013) (0)
Targeting L-type amino acid transporter 1 in urological malignancy: Current status and future perspective. (2022) (0)
Functional Characterization and Immunohistochemical Localization of Organic Anion Transporter 1 (S1c22a6) from Mouse Kidney (2004) (0)
Roles of glutamate transporters in neuronal cell death (1994) (0)
Regulation of function and localization of heterodimeric amino acid transporters by protein-protein interactions (2005) (0)
Development of anti-tumor drugs targeting amino acid transporters in cancers (2019) (0)
1125: Identification of A Novel Missense Mutation of SLC7A9 Frequent in Japanese Cystinuria Population that Cause Membrane Targeting Defect of the Transporter Protein by Introducing A Bulky Side Chain on its C -Terminus (2004) (0)
Expression of LAT1 predicts progression of transitional cell carcinoma of the upper urinary tract (2006) (0)
Suppression of LAT1 in endothelial cells of tumor tissues exhibits an anti-angiogenesis effect (2020) (0)
Amino acid transporter LAT1 (SLC7A5) on cancer cell-derived exosomes as a potential prognostic- and diagnostic biomarker. (2022) (0)
N-methyl-N-nitrosourea induced rat prostate carcinogenesis is modulated by prenatal 3, 3', 4, 4', 5-pentachlorobiphenyl exposure(Proceedings of the 32nd Annual Meeting) (2005) (0)
Human urate transporter 1 (URAT1) mediates orotic acid transport (2007) (0)
SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) in GtoPdb v.2021.3 (2021) (0)
Role of intracellular C‐terminal domain of the catalytic subunit of system b0,+ for its trafficking and the RACK1 binding. (2006) (0)
A Function-Based Genetic Analysis in a Japanese Population Common Defects of ABCG 2 , a High-Capacity Urate Exporter , Cause Gout : (2010) (0)
Molecular mechanism of substrate recognition by Leucine-Specific Binding Protein (2019) (0)
Phosphoproteome analysis reveals novel cellular responses affect by inhibition of LAT1, a cancer type amino acid transporter (2018) (0)
Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT1 (2020) (0)
[Topics in renal physiology: transgenic animals and cellular signaling]. (2008) (0)
Abstract #5508: Enhancement of cisplatin effect by the inhibitor of system L amino acid transporter 1 (2009) (0)
Transporter-mediated toxicity in the nephrotoxicity of organic compounds(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting) (2005) (0)
Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in tongue cancer. (2015) (0)
Effects of amino acid availability on the intracellular free amino acid concentration (2019) (0)
Transporters on Biomembrane: Current Progress and Future Prospects (2011) (0)
Identification and Characterization of a Na 1 -independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral D - and L -Amino Acids* (2000) (0)
Phosphate Transporter Regulator That Prevents Abnormal Hyperphosphatemia. (2021) (0)
Properties of mTORC1 regulation by amino acid signaling in HEK293T cells (2015) (0)
Combination of amino acids necessary and sufficient for the optimal activation of mTORC1 (2018) (0)

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