Yoshikazu Takada

Q: What Schools Are Affiliated With Yoshikazu Takada

Yoshikazu Takada is affiliated with the following schools: Kyoto University, Harvard University, Taipei Medical University, University of Tokyo, Princeton University, University of California, Davis, Institute of Science Tokyo, University of Washington

Yoshikazu Takada's AcademicInfluence.com Rankings

Yoshikazu Takada

Computer Science

#7735

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#8140

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Computational Linguistics

#1607

World Rank

#1624

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Machine Learning

#2962

World Rank

#2999

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Artificial Intelligence

#3257

World Rank

#3305

Historical Rank

computer-science Degrees

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Computer Science

Yoshikazu Takada's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Yoshikazu Takada's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site (1990) (1858)
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site (2001) (1071)
The integrins (2007) (828)
Fibulin-5/DANCE is essential for elastogenesis in vivo (2002) (609)
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain (1989) (342)
Structure of the Integrin VLA‐4 and its Cell‐Cell and Cell‐Matrix Adhesion Functions (1990) (340)
In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells. (1991) (334)
Characterization of the cell surface heterodimer VLA-4 and related peptides. (1987) (321)
Inhibition of tissue factor signaling suppresses tumor growth. (2008) (319)
Activated Conformations of Very Late Activation Integrins Detected by a Group of Antibodies (HUTS) Specific for a Novel Regulatory Region(355425) of the Common 1 Chain (*) (1996) (299)
Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells (1996) (255)
The primary structure of the alpha 4 subunit of VLA‐4: homology to other integrins and a possible cell‐cell adhesion function. (1989) (254)
Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies. (1993) (235)
Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1 (1990) (228)
Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3* (1998) (211)
Fibronectin receptor structures in the VLA family of heterodimers (1987) (210)
Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion (1993) (209)
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions (1993) (206)
Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA‐2 and VLA‐3 in the VLA family of heterodimers (1988) (206)
RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction* (2000) (206)
Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures. (1988) (184)
Urokinase-type Plasminogen Activator Receptor (CD87) Is a Ligand for Integrins and Mediates Cell-Cell Interaction* (2001) (179)
Integrins α2β1 and α4β1 Can Mediate SA11 Rotavirus Attachment and Entry into Cells (2000) (173)
The function and distinctive regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation. (1993) (170)
Specific Interaction of Angiostatin with Integrin αvβ3 in Endothelial Cells* (2001) (170)
Direct binding of collagen to the I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner. (1994) (169)
Cellular Interaction of Integrin α3β1 with Laminin 5 Promotes Gap Junctional Communication (1998) (168)
Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2,CD49b/CD29). (1996) (162)
Combinatorial chemistry identifies high-affinity peptidomimetics against α4β1 integrin for in vivo tumor imaging (2006) (162)
Altered rate of fibronectin matrix assembly by deletion of the first type III repeats (1996) (156)
Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies (1997) (154)
Functional Classification of ADAMs Based on a Conserved Motif for Binding to Integrin α9β1 (2002) (153)
Plasmin-induced Migration of Endothelial Cells (2002) (138)
Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C. (1995) (137)
Integrin-Using Rotaviruses Bind α2β1 Integrin α2 I Domain via VP4 DGE Sequence and Recognize αXβ2 and αVβ3 by Using VP7 during Cell Entry (2003) (136)
The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis. (1987) (135)
Cross-talk of integrin α3β1 and tissue factor in cell migration (2004) (133)
Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen (1991) (126)
ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism (2000) (122)
Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit* (1997) (121)
ADAM12/Syndecan-4 Signaling Promotes β1Integrin-dependent Cell Spreading through Protein Kinase Cα and RhoA* (2002) (118)
A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques (1992) (118)
Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling* (2008) (116)
Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29) (1995) (112)
α4β1- and α6β1-integrins are functional receptors for midkine, a heparin-binding growth factor (2004) (111)
Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling. (2002) (111)
Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1. (1998) (111)
Critical amino acid residues for ligand binding are clustered in a predicted beta‐turn of the third N‐terminal repeat in the integrin alpha 4 and alpha 5 subunits. (1995) (110)
Induction of experimental bone metastasis in mice by transfection of integrin α4β1 into tumor cells (1996) (107)
Superoxide dismutase in various tissues from rabbits bearing the Vx-2 carcinoma in the maxillary sinus. (1982) (107)
Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon. (1990) (105)
Critical Threonine and Aspartic Acid Residues within the I Domains of β2 Integrins for Interactions with Intercellular Adhesion Molecule 1 (ICAM-1) and C3bi (*) (1995) (102)
Multiple Discontinuous Ligand-mimetic Antibody Binding Sites Define a Ligand Binding Pocket in Integrin αIIbβ3 * (2000) (101)
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. (2006) (95)
Critical Residues for Ligand Binding in an I Domain-like Structure of the Integrin β1 Subunit* (1996) (94)
Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. (2004) (89)
Human Parechovirus 1 Utilizes Integrins αvβ3 and αvβ1 as Receptors (2000) (89)
Peroxisomal localization of alanine: glyoxylate aminotransferase in human liver. (1979) (88)
Critical Residues of Integrin αIIb Subunit for Binding of αIIbβ3 (Glycoprotein IIb-IIIa) to Fibrinogen and Ligand-mimetic Antibodies (PAC-1, OP-G2, and LJ-CP3)* (1996) (87)
Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions. (2002) (86)
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species. (1978) (83)
Identification of Amino Acid Sequences in Fibrinogen γ-Chain and Tenascin C C-terminal Domains Critical for Binding to Integrin αvβ3 * (2000) (80)
Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3. (1998) (80)
Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. (2009) (79)
Amino Acid Residues in the αIIb Subunit That Are Critical for Ligand Binding to Integrin αIIbβ3 Are Clustered in the β-Propeller Model* (2001) (79)
Mechanisms of integrin-mediated virus attachment and internalization process. (2001) (79)
The Direct Binding of Insulin-like Growth Factor-1 (IGF-1) to Integrin αvβ3 Is Involved in IGF-1 Signaling* (2009) (78)
Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner* (2008) (78)
RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction. (2000) (77)
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. (2012) (73)
Plasmin-induced Migration Requires Signaling through Protease-activated Receptor 1 and Integrin α9β1* (2004) (71)
Specific binding of integrin αvβ3 to the fibrinogen γ and α(E) chain C-terminal domains (1999) (71)
Critical Role of Integrin α5β1 in Urokinase (uPA)/Urokinase Receptor (uPAR, CD87) Signaling* (2003) (69)
Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry. (2003) (65)
The Use of One-Bead One-Compound Combinatorial Library Technology to Discover High-Affinity αvβ3 Integrin and Cancer Targeting Arginine-Glycine-Aspartic Acid Ligands with a Built-in Handle (2010) (65)
Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit. (2004) (64)
Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells. (1996) (64)
Subcellular distribution of pyruvate (glyoxylate) aminotransferases in rat liver. (1978) (63)
Multiple loop structures critical for ligand binding of the integrin α4 subunit in the upper face of the β-propeller mode 1 (1997) (61)
Involvement of beta2-microglobulin and integrin alphavbeta3 molecules in the coxsackievirus A9 infectious cycle. (1999) (61)
Direct Binding of the EGF-like Domain of Neuregulin-1 to Integrins (αvβ3 and α6β4) Is Involved in Neuregulin-1/ErbB Signaling* (2010) (60)
Distinct Functions of Integrin ct and/3 Subunit Cytoplasmic Domains in Cell Spreading and Formation of Focal Adhesions (1993) (60)
Adhesion of Gastric Carcinoma Cells to Peritoneum Mediated by α3β1 Integrin (VLA-3) (2004) (59)
A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis (2013) (58)
Rotaviruses interact with α4β7 and α4β1 integrins by binding the same integrin domains as natural ligands (2005) (54)
Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit. (1997) (54)
The Role of the CPNKEKEC Sequence in the β2 Subunit I Domain in Regulation of Integrin αLβ2 (LFA-1)1 (2002) (54)
Enhanced Activity of Transforming Growth Factor β1 (TGF-β1) Bound to Cartilage Oligomeric Matrix Protein* (2011) (54)
Degradation of uric acid to urea and glyoxylate in peroxisomes. (1979) (53)
Multiple ligand binding functions for VLA-2 α2β1 and VLA-3 (α3β1) in the integrin family (1990) (52)
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin αvβ3 induces signal transduction and enhances plasminogen activation (2006) (52)
Regulation of Conformation and Ligand Binding Function of Integrin α5β1 by the β1 Cytoplasmic Domain* (1996) (51)
Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes in different mammalian species. (1982) (51)
alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor. (2004) (50)
Propolypeptide of von Willebrand Factor Is a Novel Ligand for Very Late Antigen-4 Integrin* (1997) (50)
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule (1991) (49)
Expression level of integrin α5 on tumour cells affects the rate of metastasis to the kidney (2003) (48)
Interaction between collagen and the α2 I-domain of integrin αβ1: Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region (1999) (47)
Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells (2015) (46)
Echovirus 1 interaction with the human very late antigen-2 (integrin alpha2beta1) I domain. Identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site. (1997) (46)
Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family. (2006) (45)
Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates. (1985) (44)
Role of integrin αvβ3 in the early phase of liver metastasis: PET and IVM analyses (2004) (44)
Peroxisomal localization of serine:pyruvate aminotransferase in human liver. (1978) (43)
ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alphavbeta3 integrin through an RGD-independent mechanism. (2000) (42)
A Novel Activating Anti-β1 Integrin Monoclonal Antibody Binds to the Cysteine-rich Repeats in the β1 Chain* (1996) (41)
Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1). (2004) (40)
Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1. (2017) (39)
Adhesion of gastric carcinoma cells to peritoneum mediated by alpha3beta1 integrin (VLA-3). (2004) (38)
Differential regulation of cellular adhesion and migration by recombinant laminin‐5 forms with partial deletion or mutation within the G3 domain of α3 chain (2003) (38)
Cross-talk between Integrin α6β4 and Insulin-like Growth Factor-1 Receptor (IGF1R) through Direct α6β4 Binding to IGF1 and Subsequent α6β4-IGF1-IGF1R Ternary Complex Formation in Anchorage-independent Conditions* (2012) (38)
Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling. (2003) (38)
Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29) (1995) (37)
Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope. (1997) (35)
α3β1 Adhesion to Laminin-5 and Invasin: Critical and Differential Role of Integrin Residues Clustered at the Boundary between α3 N-Terminal Repeats 2 and 3† (1999) (35)
Structural basis of integrin-mediated signal transduction. (1997) (35)
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation. (2006) (35)
Integrins αvβ3 and α4β1 Act as Coreceptors for Fractalkine, and the Integrin-Binding Defective Mutant of Fractalkine Is an Antagonist of CX3CR1 (2012) (35)
The Role of α and β Chains in Ligand Recognition by β7 Integrins* (2000) (34)
Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit. (1997) (33)
Fibrinogen-&ggr; C-Terminal Fragments Induce Endothelial Barrier Dysfunction and Microvascular Leak via Integrin-Mediated and RhoA-Dependent Mechanism (2009) (33)
Integrin α3β1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes (1999) (33)
Insulin-like Growth Factor (IGF) Signaling Requires αvβ3-IGF1-IGF Type 1 Receptor (IGF1R) Ternary Complex Formation in Anchorage Independence, and the Complex Formation Does Not Require IGF1R and Src Activation (2012) (33)
Purification and properties of peroxisomal pyruvate (glyoxylate) aminotransferase from rat liver. (1978) (32)
Rotavirus spike protein VP5* binds α2β1 integrin on the cell surface and competes with virus for cell binding and infectivity (2006) (32)
Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin (2015) (32)
Attachment of Human Colon Cancer Cells to Vascular Endothelium Is Enhanced by N-Acetylglucosaminyltransferase V (2004) (31)
High affinity interactions of Coxsackievirus A9 with integrin αvβ3 (CD51/61) require the CYDMKTTC sequence of β3, but do not require the RGD sequence of the CAV-9 VP1 protein (2000) (31)
Intraperoxisomal and intramitochondrial localization, and assay of pyruvate (glyoxylate) aminotransferase from rat liver. (1979) (30)
The degradation of urate in liver peroxisomes. Association of allantoinase with allantoicase in amphibian liver but not in fish and invertebrate liver. (1983) (30)
The COOH-Terminal Globular Domain of Fibrinogen γ Chain Suppresses Angiogenesis and Tumor Growth (2006) (30)
Monkey Rotavirus Binding to α2β1 Integrin Requires the α2 I Domain and Is Facilitated by the Homologous β1 Subunit (2003) (28)
Rotaviruses interact with alpha4beta7 and alpha4beta1 integrins by binding the same integrin domains as natural ligands. (2005) (28)
Specific binding of integrin alpha v beta 3 to the fibrinogen gamma and alpha E chain C-terminal domains. (1999) (28)
VLA‐4 Molecules on Tumor Cells Initiate an Adhesive Interaction with VCAM‐1 Molecules on Endothelial Cell Surface (1992) (28)
Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses. (2002) (27)
Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3). (2000) (27)
Determinants of the Specificity of Rotavirus Interactions with the α2β1 Integrin* (2010) (27)
ADAM12‐mediated focal adhesion formation is differently regulated by β1 and β3 integrins (2005) (26)
Molecular Cloning and Expression of the cDNA for a 3 Subunit of Human a 3 aJVLA-3), an Integrin Receptor for Fibronectin, Laminin, and Collagen (1991) (26)
An Integrin Binding-defective Mutant of Insulin-like Growth Factor-1 (R36E/R37E IGF1) Acts as a Dominant-negative Antagonist of the IGF1 Receptor (IGF1R) and Suppresses Tumorigenesis but Still Binds to IGF1R* (2013) (26)
A Novel Fibroblast Growth Factor-1 (FGF1) Mutant that Acts as an FGF Antagonist (2010) (26)
Novel point mutations in the αIIb subunit (Phe289 → Ser, Glu324 → Lys and Gln747 → Pro) causing thrombasthenic phenotypes in four Japanese patients (1998) (25)
Ureidoglycollate lyase, a new metalloenzyme of peroxisomal urate degradation in marine fish liver. (1986) (25)
Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model. (2001) (25)
Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells (2018) (25)
The Chemokine Fractalkine Can Activate Integrins without CX3CR1 through Direct Binding to a Ligand-Binding Site Distinct from the Classical RGD-Binding Site (2014) (25)
Rotavirus spike protein VP5* binds alpha2beta1 integrin on the cell surface and competes with virus for cell binding and infectivity. (2006) (24)
Mutational Analysis of Cell Cycle Inhibition by Integrin β1C * (1999) (24)
Effects on Rotavirus Cell Binding and Infection of Monomeric and Polymeric Peptides Containing α2β1 and αxβ2 Integrin Ligand Sequences (2004) (24)
Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells (2011) (24)
The Binding of Monomeric C-Reactive Protein (mCRP) to Integrins αvβ3 and α4β1 Is Related to Its Pro-Inflammatory Action (2014) (24)
The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis (2017) (24)
Proinflammatory Secreted Phospholipase A2 Type IIA (sPLA-IIA) Induces Integrin Activation through Direct Binding to a Newly Identified Binding Site (Site 2) in Integrins αvβ3, α4β1, and α5β1* (2014) (23)
A serine-to-phenylalanine substitution leads to loss of alanine:glyoxylate aminotransferase catalytic activity and immunoreactivity in a patient with primary hyperoxaluria type 1. (1992) (23)
Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit. (2000) (23)
Rotavirus-neutralizing antibodies inhibit virus binding to integrins α2β1 and α4β1 (2007) (22)
Involvement of β2-microglobulin and integrin αvβ3 molecules in the coxsackievirus A9 infectious cycle (1999) (21)
The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin αvβ3. (2017) (21)
Novel peptide ligands for integrin α4β1 overexpressed in cancer cells (2004) (21)
The effect of vitamin B6 deficiency on alanine: glyoxylate aminotransferase isoenzymes in rat liver. (1984) (21)
Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4. (2018) (21)
The role of the CPNKEKEC sequence in the beta(2) subunit I domain in regulation of integrin alpha(L)beta(2) (LFA-1). (2002) (21)
Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling (2019) (21)
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth. (2006) (18)
The 'ligand-induced conformational change' of alpha 5 beta 1 integrin. Relocation of alpha 5 subunit to uncover the beta 1 stalk region. (1998) (18)
Identification of Equine Lactadherin-derived Peptides That Inhibit Rotavirus Infection via Integrin Receptor Competition* (2015) (18)
Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3). (1996) (18)
Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes. (1999) (16)
Expression of integrins to control migration direction of electrotaxis (2019) (16)
Tunable hydrogels for mesenchymal stem cell delivery: Integrin‐induced transcriptome alterations and hydrogel optimization for human wound healing (2019) (16)
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. (2013) (16)
Crosstalk between Fibroblast Growth Factor (FGF) Receptor and Integrin through Direct Integrin Binding to FGF and Resulting Integrin-FGF-FGFR Ternary Complex Formation (2013) (16)
Interaction between collagen and the alpha(2) I-domain of integrin alpha(2)beta(1). Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region. (1999) (15)
Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner. (2016) (15)
Model of the αLβ2 integrin I‐domain/ICAM‐1 DI interface suggests that subtle changes in loop orientation determine ligand specificity (2002) (15)
Multiple ligand binding functions for VLA-2 (alpha 2 beta 1) and VLA-3 (alpha 3 beta 1) in the integrin family. (1990) (15)
Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences. (2004) (15)
Characteristics of hepatic serine-pyruvate aminotransferase in different mammalian species. (1977) (15)
Alpha 3 beta 1 adhesion to laminin-5 and invasin: critical and differential role of integrin residues clustered at the boundary between alpha 3 N-terminal repeats 2 and 3. (1999) (14)
Rotavirus-neutralizing antibodies inhibit virus binding to integrins alpha 2 beta 1 and alpha 4 beta 1. (2007) (14)
The role of alpha and beta chains in ligand recognition by beta 7 integrins. (2000) (14)
ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins. (2005) (14)
A novel activating anti-beta1 integrin monoclonal antibody binds to the cysteine-rich repeats in the beta1 chain. (1996) (13)
Platelet Integrin αIIbβ3-Ligand Interactions: What Can We Learn From the Structure? (2001) (13)
Glutamate-glyoxylate aminotransferase in rat liver cytosol. Purification, properties and identity with alanine-2-oxoglutarate aminotransferase. (1977) (13)
Large-animal models of fulminant hepatic failure (2003) (12)
The evolution of peroxisomal and mitochondrial alanine: glyoxylate aminotransferase 1 in mammalian liver. (1982) (12)
Kidney alanine: Glyoxylate aminotransferase isoenzymes; species distribution, subcellular distribution and properties (1980) (11)
Pro-inflammatory Secretory Phospholipase A 2 Type IIA Binds to Integrins (2008) (11)
Effects of fibronectin cleaved by neuropsin on cell adhesion and migration (2001) (11)
A T cell-binding fragment of fibrinogen can prevent autoimmunity. (2010) (10)
Chinese Hamster Ovary Cells Expressing α4β1 Integrin Stimulate Osteoclast Formation In Vitro (1998) (10)
Direct binding to integrins and loss of disulfide linkage in interleukin-1β (IL-1β) are involved in the agonistic action of IL-1β (2017) (9)
Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling (2017) (9)
A Point Mutation of Integrin/3 Subunit Blocks Binding of Otsi3 to Fibronectin and Invasin but not Recruitment to Adhesion Plaques (2002) (9)
Non-cytotoxic Cobra Cardiotoxin A5 Binds to αvβ3 Integrin and Inhibits Bone Resorption (2006) (8)
Structure and Functions for the Adhesion Receptors VLA-2 and VLA-4: Comparisons to other Members of the Integrin Superfamily (1990) (8)
Ligand-induced epitope masking. Dissociation of integrin 51-fibronectin complexes only by monoclonal antibodies with an allosteric mode of action. (2018) (8)
Ligand-induced Epitope Masking (2016) (8)
Integrins : biological problems (2017) (8)
Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells. (2004) (7)
High affinity interactions of Coxsackievirus A9 with integrin alphavbeta3 (CD51/61) require the CYDMKTTC sequence of beta3, but do not require the RGD sequence of the CAV-9 VP1 protein. (2000) (7)
Metabolism of urea and glyoxylate, degradative products of purines in marine animals. (1982) (7)
Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT‐1080 cells (2012) (7)
Anti-Monomeric C-Reactive Protein Antibody Ameliorates Arthritis and Nephritis in Mice (2021) (7)
Critical cysteine residues for regulation of integrin αIIbβ3 are clustered in the epidermal growth factor domains of the β3 subunit (2004) (6)
Mutational analysis of cell cycle inhibition by integrin beta1C. (1999) (6)
Echovirus 1 Interaction with the Human Very Late Antigen-2 (Integrin α2β1) I Domain (1997) (6)
Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1. (1997) (6)
Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain. (1996) (6)
Specific Interaction of Angiostatin with Integrin (cid:1) v (cid:2) 3 in Endothelial Cells* (2001) (6)
Platelet integrin alphaIIbbeta3-ligand interactions: what can we learn from the structure? (2001) (6)
Aromatic-amino acid-glyoxylate aminotransferase from rat liver. (1987) (5)
Increase in hepatic pyruvate (glyoxylate) aminotransferase activity on administration of clofibrate to the rat. (1981) (5)
Identification of Amino Acid Sequences in Fibrinogen g -Chain and Tenascin C C-terminal Domains Critical for Binding to Integrin a v b 3 * (2000) (4)
Potential Role of Kringle-Integrin Interaction in Plasmin and uPA Actions (A Hypothesis) (2012) (4)
ADAM12/syndecan-4 signaling promotes β 1 integrin-dependent cell spreading through PKC α and RhoA (2002) (4)
The appearance of a new aromatic aminotransferase in the small intestines of vitamin B6-deficient rats. (1980) (4)
Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity. (2002) (3)
Chinese hamster ovary cells expressing alpha4beta1 integrin stimulate osteoclast formation in vitro. (1998) (3)
Urokinase receptor (upar/cd87) is a genuine ligand for integrins and mediates cell-cell interaction (2000) (3)
FGF1 (fibroblast growth factor 1 (acidic)) (2014) (2)
The Binding of Monomeric C-Reactive Protein ( mCRP ) to Integrins a v b 3 and a 4 b 1 Is Related to Its Pro-Inflammatory Action (2014) (2)
Enzymatic and immunological comparison of alanine: glyoxylate aminotransferases from different fish and mammalian livers. (1984) (2)
A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29). (2002) (2)
Interaction between Collagen and the α2 I-domain of Integrin α2β1 (1999) (2)
Soluble CD40L activates soluble and cell-surface integrin αvβ3, α5β1, and α4β1 by binding to the allosteric ligand-binding site (site 2) (2021) (2)
Human Parechovirus 1 Utilizes Integrins a v b 3 and a v b 1 as Receptors (2000) (2)
Relocation of α5 subunit to uncover the β1 stalk region (1998) (1)
Amino Acid Residues in the IIb Subunit That Are Critical for Ligand Binding to Integrin (2001) (1)
Promotes Gap Junctional Communication (1998) (1)
Purine Degradation and Animal Evolution (1981) (1)
Pro-Inflammatory Chemokines CCL5, CXCL12, and CX3CL1 Bind to and Activate Platelet Integrin αIIbβ3 in an Allosteric Manner (2022) (1)
Identification of Novel Site 2 Targeting peptides Using One-Bead One-Compound Technology (2018) (0)
1 as Receptors β v α 3 and β v α Human Parechovirus 1 Utilizes Integrins (2014) (0)
[Molecular mechanisms of integrin-ligand interaction]. (1997) (0)
The use of OBOC library technology to discover high-affinity alphavbeta3 integrin and cancer targeting RGD ligands with a build-in handle (2010) (0)
Abstract LB-5: The dominant-negative effect of an insulin-like growth factor-1 mutant that is defective in binding to integrins (αvβ3 and α6β4) (2011) (0)
Correction: Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29) (Biochemical Journal (1996) 305 (945-951)) (1996) (0)
Structure and Function of Integrin Extracellular Domain (1998) (0)
Theoretical Model of the beta-Propeller Domain of Integrin alphaIIb (2001) (0)
Abstract 272: Direct binding of neuregulin-1 to integrins is involved in neuregulin-1/ErbB signaling (2010) (0)
Erratum to “A T cell-binding fragment of fibrinogen can prevent autoimmunity” [J. Autoimmun. 34 (2010) 453–459] (2011) (0)
[Analysis of the mechanism of tumor metastasis by the transfection of integrin cDNA]. (1995) (0)
Purification, characterization and identification of aromatic 2-oxo acid reductase. (1977) (0)
The effect of the truncated fibrinogen fragment γC399tr on tumor growth in the Met‐1 mouse mammary tumor model (2007) (0)
ID: 058 The C-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth (2006) (0)
The C-terminal globular domain of fibrinogen {gamma} chain suppresses angiogenesis and tumor growth (2006) (0)
The C-type lectin domain of CD62P (P-selectin) is an integrin ligand (2022) (0)
[Subclassification, molecular structure, function and ligand in integrin superfamily]. (1995) (0)
From OBOC combinatorial chemistry to glioblastoma targeting (2007) (0)
Additions and Corrections (2009) (0)
Angiogenesis , Metastasis , and the Cellular Microenvironment Silencing of DLC 1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells (2011) (0)
Contents Vol. 66, 2004 (2004) (0)
of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin induces signal transduction and enhances plasminogen activation. (2006) (0)
Anti-PF4 (heparin-independent)/PF4 complex induces allosteric activation of integrins αIIbβ3 and αvβ3, a potential mechanism of vaccine-induced thrombotic thrombocytopenia (VITT) and autoimmune diseases (2022) (0)
THE C‐TERMINAL GLOBULAR DOMAIN OF FIBRINOGEN γ CHAIN INDUCES ENDOTHELIAL BARRIER DYSFUNCTION AND MICROVASCULAR LEAKAGE VIA A RHOA‐DEPENDENT MECHANISM (2009) (0)
Abstract LB-007: Interaction between integrin α4β1 and IGF1 and its role in IGF signaling in hematologic malignancies (2016) (0)
A Dominant-Negative FGF2 Mutant Suppresses Angiogenesis (2016) (0)
THE CELL TO CELL INTERACTION OF BREAST CANCER CELLS REGULATES CANCER INVASION VIA ADAM15 (2012) (0)
Urease and Glyoxylate Aminotransferase in Marine Animals (1982) (0)
Antagonist of CX 3 CR 1 Defective Mutant of Fractalkine Is an for Fractalkine , and the Integrin-Binding Act as Coreceptors 1 β 4 α and 3 β v α Integrins (2012) (0)
Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells (2018) (0)
Model of the aLb2 I-domain / ICAM-1 D1 complex (2002) (0)
[Integrin family]. (1996) (0)
Abstract P1-05-02: Novel mechanisms of Rac1 activation by the Cullin-3/KCTD10 ubiquitin E3 complex in HER2-positive breast cancer (2019) (0)
The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand (2023) (0)
Subject Index Vol. 66, 2004 (2004) (0)
The very late antigen family of hete superfamily of molecules involved ii (2016) (0)
CD40L acts as an allosteric activator of integrins for signal transduction independent of inside-out signaling (2021) (0)
High Affinity High Specificity α4β1 Integrin Targeting Peptidomimetics for Lymphoid Cancers (2006) (0)
Integrin Subunit I Domain in Regulation of 2 b The Role of the CPNKEKEC Sequence in the (2002) (0)

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