Yoshikuni Mizuno
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Neuroscience
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Biology
Yoshikuni Mizuno's Degrees
- PhD Medicine University of Tokyo
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(Suggest an Edit or Addition)Yoshikuni Mizuno's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism (1998) (4916)
- Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase (2000) (2014)
- Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease (2001) (1064)
- An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin (2001) (1036)
- Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. (1996) (960)
- Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force (2007) (918)
- Protein-bound acrolein: potential markers for oxidative stress. (1998) (595)
- Mitochondrial genome variation in eastern Asia and the peopling of Japan. (2004) (525)
- Histochemical detection of apoptosis in Parkinson's disease (1996) (472)
- Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. (1996) (424)
- Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27. (1997) (384)
- Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease (1999) (368)
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue (2012) (328)
- Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. (2002) (325)
- A possible role for humoral immunity in the pathogenesis of Parkinson's disease. (2005) (299)
- Methylglyoxal Modification of Protein (1999) (295)
- Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals (1998) (293)
- Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in parkinson's disease (1991) (279)
- Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients (1999) (269)
- Clinical heterogeneity of α‐synuclein gene duplication in Parkinson's disease (2006) (265)
- CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study (2015) (265)
- Edaravone Reduces Early Accumulation of Oxidative Products and Sequential Inflammatory Responses After Transient Focal Ischemia in Mice Brain (2005) (260)
- Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin‐like domain (2003) (258)
- Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. (2005) (246)
- Overexpression of α‐synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of α‐synuclein and activation of caspase‐9: resemblance to pathogenetic changes in Parkinson's disease (2004) (236)
- Novel PINK1 mutations in early‐onset parkinsonism (2004) (228)
- p53 protein, interferon-γ, and NF-κB levels are elevated in the parkinsonian brain (2007) (197)
- Neuroprotective Effect of Recombinant Human Granulocyte Colony-Stimulating Factor in Transient Focal Ischemia of Mice (2006) (186)
- Diverse Effects of Pathogenic Mutations of Parkin That Catalyze Multiple Monoubiquitylation in Vitro* (2006) (185)
- Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease. (2006) (183)
- Adenosine A2A receptor antagonist istradefylline reduces daily OFF time in Parkinson’s disease (2013) (179)
- An immunohistochemical study on α‐ketoglutarate dehydrogenase complex in Parkinson's disease (1994) (175)
- Role of mitochondria in the etiology and pathogenesis of Parkinson's disease. (1995) (172)
- Effect of Wild-type or Mutant Parkin on Oxidative Damage, Nitric Oxide, Antioxidant Defenses, and the Proteasome* (2002) (172)
- Clinical efficacy of istradefylline (KW‐6002) in Parkinson's disease: A randomized, controlled study (2010) (166)
- Milestones in PD genetics (2011) (163)
- A reassessment of risks and benefits of dopamine agonists in Parkinson's disease (2009) (163)
- A Combinatorial Code for the Interaction of α-Synuclein with Membranes* (2005) (162)
- Point Mutations (Thr240Arg and Ala311Stop) in theParkinGene (1998) (161)
- Increased 8‐oxo‐dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease (1999) (160)
- An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease (2001) (151)
- Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial (2013) (149)
- Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism (2005) (147)
- Leucine-rich repeat kinase 2 associates with lipid rafts. (2007) (147)
- Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat (1994) (146)
- [Clinical subtypes of Parkinson's disease]. (1993) (139)
- Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease (1990) (133)
- Pathogenetic mechanisms of parkin in Parkinson's disease (2004) (133)
- Leucine-Rich Repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population (2007) (132)
- Prognosis of Parkinson's disease: Time to stage III, IV, V, and to motor fluctuations (2006) (132)
- Possibility for neurogenesis in substantia nigra of parkinsonian brain (2005) (131)
- Parkin is associated with cellular vesicles (2001) (131)
- Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys (1994) (130)
- Expanding the clinical phenotype of SNCA duplication carriers (2009) (127)
- Caspase-11 Mediates Inflammatory Dopaminergic Cell Death in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson's Disease (2004) (122)
- Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries (2006) (122)
- Diagnostic Accuracy of 123I-Meta-Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies: A Multicenter Study (2015) (121)
- Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson’s disease and related neurodegenerative disorders (2005) (120)
- Neurotoxic Effects of Lipopolysaccharide on Nigral Dopaminergic Neurons Are Mediated by Microglial Activation, Interleukin-1β, and Expression of Caspase-11 in Mice* (2004) (119)
- Ubiquitin, proteasome and parkin. (2004) (118)
- Multiplex families with multiple system atrophy. (2007) (116)
- p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain. (2007) (116)
- Parkin and Parkinson's disease (2001) (115)
- Parkin attenuates manganese‐induced dopaminergic cell death (2004) (115)
- Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease (2005) (113)
- The fate of neural progenitor cells expressing astrocytic and radial glial markers in the postnatal rat dentate gyrus (2005) (113)
- Cilostazol Protects Against Brain White Matter Damage and Cognitive Impairment in a Rat Model of Chronic Cerebral Hypoperfusion (2006) (112)
- bcl-2 Protein is increased in the brain from parkinsonian patients (1996) (112)
- Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease. (2005) (111)
- 14‐3‐3η is a novel regulator of parkin ubiquitin ligase (2006) (111)
- A Long-Term Study of Istradefylline Safety and Efficacy in Patients With Parkinson Disease (2015) (110)
- Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth (2009) (110)
- Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant (2007) (104)
- The soluble form of Fas molecule is elevated in parkinsonian brain tissues (1996) (102)
- Siah-1 Facilitates Ubiquitination and Degradation of Synphilin-1* (2003) (102)
- Polymorphism of the Lipoprotein Lipase Gene and Risk of Atherothrombotic Cerebral Infarction in the Japanese (2001) (101)
- Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity by 1-methyl-4-phenylpyridinium ion. (1987) (100)
- A combinatorial code for the interaction of alpha-synuclein with membranes. (2005) (98)
- Neurogenesis After Transient Global Ischemia in the Adult Hippocampus Visualized by Improved Retroviral Vector (2004) (96)
- Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion. (1987) (95)
- Polymorphism in the parkin gene in sporadic Parkinson's disease (1999) (94)
- Malignant syndrome in Parkinson's disease: concept and review of the literature. (2003) (94)
- Intrinsic and extrinsic erythropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro (2006) (94)
- A collaborative study on the malignant syndrome in Parkinson's disease and related disorders. (2003) (92)
- Pergolide in the treatment of Parkinson's disease (1984) (90)
- Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease (2006) (89)
- Randomized, double‐blind, multicenter evaluation of pramipexole extended release once daily in early Parkinson's disease (2010) (89)
- Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain in vivo (1988) (88)
- GTP‐cyclohydrolase I gene mutations in hereditary progressive and dopa‐responsive dystonia (1996) (88)
- Preserved cardiac sympathetic nerve accounts for normal cardiac uptake of MIBG in PARK2 (2005) (88)
- Relationship of phosphorylated α-synuclein and tau accumulation to Aβ deposition in the cerebral cortex of dementia with Lewy bodies (2008) (87)
- Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study. (2003) (85)
- Familial Parkinson's disease. Alpha-synuclein and parkin. (2001) (83)
- Progress in the pathogenesis and genetics of Parkinson's disease (2008) (82)
- Parkin stabilizes PINK1 through direct interaction. (2009) (82)
- Mitochondrial dysfunction in parkinson's disease (1998) (81)
- Neurotrophic and neuroprotective effects of neuron-specific enolase on cultured neurons from embryonic rat brain (1995) (81)
- Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson’s disease rat model ☆ (2006) (80)
- Extended-release pramipexole in early Parkinson disease (2011) (80)
- Inhibition of ATP synthesis by 1-methyl-4-phenylpyridinium ion (MPP+) in isolated mitochondria from mouse brains (1987) (79)
- Autosomal recessive early-onset parkinsonism with diurnal fluctuation: clinicopathologic characteristics and molecular genetic identification (2000) (79)
- Mutation analysis of the PINK1 gene in 391 patients with Parkinson disease. (2008) (78)
- Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated adult mice (2004) (78)
- Is Parkinson's disease a mitochondrial disorder? (1992) (77)
- Effect of Dopamine, Dimethoxyphenylethylamine, Papaverine, and Related Compounds on Mitochondrial Respiration and Complex I Activity (1996) (77)
- Parkin is linked to the ubiquitin pathway (2001) (74)
- Reciprocal Ia inhibition in patients with asymmetric spinal spasticity (2002) (74)
- Generalized Convulsions After Consuming a Large Amount of Gingko Nuts (2001) (73)
- A novel L266V mutation of the tau gene causes frontotemporal dementia with a unique tau pathology (2003) (73)
- Randomized, double‐blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease (2003) (72)
- Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion (2012) (72)
- Studies on the toxicity of 1-methyl-4-phenylpyridinium ion (MPP+) against mitochondria of mouse brain (1988) (71)
- PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations (2004) (71)
- Parkin Cleaves Intracellular α-Synuclein Inclusions via the Activation of Calpain* (2003) (71)
- Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein (2002) (70)
- Neurochemical and Neurogenetic Correlates of Parkinson's Disease (1998) (69)
- Minimal Clinically Important Difference in Parkinson's Disease as Assessed in Pivotal Trials of Pramipexole Extended Release (2014) (68)
- Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene (2000) (68)
- Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene. (1998) (64)
- Pro‐apoptotic protein glyceraldehyde‐3‐phosphate dehydrogenase promotes the formation of Lewy body‐like inclusions (2005) (63)
- The neuromythology of Parkinson's Disease. (2004) (62)
- Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction. (2004) (62)
- Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice (1987) (61)
- Clinical trial of piracetam in patients with myoclonus: Nationwide multiinstitution study in Japan (1996) (61)
- Changes in superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activities and thiobarbituric acid-reactive products levels in early stages of development in dystrophic chickens (1984) (60)
- Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease (2011) (59)
- Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease. (1998) (59)
- Effects of UCH‐L1 on α‐synuclein over‐expression mouse model of Parkinson’s disease (2009) (59)
- An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease. (1994) (59)
- Inflammation and infection in Parkinson's disease. (2006) (59)
- Parkin and Endoplasmic Reticulum Stress (2003) (58)
- Decline of striatal dopamine release in parkin‐deficient mice shown by ex vivo autoradiography (2006) (57)
- I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway. (2015) (57)
- Adult type neuronal storage disease with neuraminidase deficiency (1979) (57)
- Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells (2005) (57)
- Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain (2000) (56)
- Prevention and treatment of malignant syndrome in Parkinson's disease: a consensus statement of the malignant syndrome research group. (2003) (56)
- Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease (2007) (55)
- Posterior hypoperfusion in parkinson's disease With and without dementia measured with arterial spin labeling MRI (2011) (54)
- New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism (2003) (54)
- Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins (1997) (52)
- Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains (2001) (52)
- Accumulation of α-Synuclein Triggered by Presynaptic Dysfunction (2012) (51)
- Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson’s disease (2006) (50)
- Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain (1992) (50)
- PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism. (2000) (50)
- Autosomal-recessive juvenile parkinsonism in a Jewish Yemenite kindred: mutation of Parkin gene. (1999) (49)
- Rotigotine vs ropinirole in advanced stage Parkinson's disease: a double-blind study. (2014) (48)
- Clinical, pathologic and genetic studies on autosomal recessive early-onset parkinsonism with diurnal fluctuation. (1998) (48)
- A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2). (1998) (48)
- Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model. (2006) (48)
- Familial Parkinsonism with digenic parkin and PINK1 mutations (2008) (48)
- Point mutations in mitochondrial tRNA genes: sequence analysis of chronic progressive external ophthalmoplegia (CPEO) (1994) (47)
- Mitochondrial dysfunction in Parkinson's disease. (2002) (47)
- Recurrent cranial neuropathy as a clinical presentation of idiopathic inflammation of the dura mater: a possible relationship to Tolosa-Hunt syndrome and cranial pachymeningitis (1998) (47)
- Recessive Parkinson's disease (2006) (46)
- Clinical and genetic studies of families with the tau N279K mutation (FTDP-17) (2002) (46)
- Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity and ATP synthesis by tetrahydroisoquinoline (1988) (45)
- Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration. (2002) (45)
- Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes (1998) (44)
- Neuronal specificity of alpha-synuclein toxicity and effect of Parkin co-expression in primates. (2007) (44)
- Rationale for delayed‐start study of pramipexole in Parkinson's disease: The PROUD study (2010) (42)
- Lewy body pathology in a patient with a homozygous Parkin deletion (2013) (42)
- Haploinsufficiency at the α‐synuclein gene underlies phenotypic severity in familial Parkinson’s disease (2003) (41)
- Recombinant human granulocyte colony‐stimulating factor protects against MPTP‐induced dopaminergic cell death in mice by altering Bcl‐2/Bax expression levels (2006) (41)
- Camptocormia, axial dystonia, and parkinsonism: Phenotypic heterogeneity of a parkin mutation (2003) (41)
- Changes in γ-aminobutyrate, glutamate, aspartate, glycine, and taurine contents in the striatum after unilateral nigrostriatal lesions in rats (1986) (40)
- Cortical ballooned neurons in progressive supranuclear palsy (1996) (40)
- Significance of CSF total neopterin and biopterin in inflammatory neurological diseases (1992) (40)
- Mechanism and treatment of dropped head syndrome associated with parkinsonism. (2009) (40)
- Ropinirole is effective on motor function when used as an adjunct to levodopa in Parkinson's disease: STRONG study (2007) (40)
- Induction of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Expression in Rat Brain after Focal Ischemia/Reperfusion (2002) (40)
- Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells. (2005) (40)
- Placebo‐controlled, double‐blind dose‐finding study of entacapone in fluctuating parkinsonian patients (2007) (39)
- Familial cortical tremor with epilepsy: an under-recognized familial tremor (1998) (39)
- Progress in the clinical and molecular genetics of familial parkinsonism (2000) (39)
- Parkin gene causing benign autosomal recessive juvenile parkinsonism (2001) (38)
- An immunohistochemical study on manganese superoxide dismutase in Parkinson's disease (1997) (38)
- Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain. (2003) (38)
- Early onset parkinsonism with diurnal fluctuation maps to a locus for juvenile parkinsonism (1998) (38)
- The frequency of cardiac valvular regurgitation in Parkinson's disease (2008) (37)
- Autosomal recessive juvenile parkinsonism: A key to understanding nigral degeneration in sporadic Parkinson's disease (2000) (37)
- Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders (2003) (35)
- Official Japanese Version of the International Parkinson and Movement Disorder Society–Unified Parkinson's Disease Rating Scale: Validation Against the Original English Version (2014) (35)
- 123I-MIBG myocardial scintigraphy for the diagnosis of DLB: a multicentre 3-year follow-up study (2018) (34)
- Association between the gene encoding the E2 subunit of the α‐ketoglutarate dehydrogenase complex and Parkinson's disease (1998) (34)
- Dual Role of Fc&ggr; Receptor in Transient Focal Cerebral Ischemia in Mice (2004) (34)
- Genetic association between susceptibility to Parkinson's disease and α 1-antichymotrypsin polymorphism (1997) (34)
- Sweet's syndrome associated with encephalitis (2001) (33)
- Efficacy, safety, and tolerability of overnight switching from immediate‐ to once daily extended‐release pramipexole in early Parkinson's disease (2010) (33)
- Programmed cell death‐2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease (2009) (33)
- An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome (2006) (32)
- Music therapy in parkinson's disease: Improvement of parkinsonian gait and depression with rhythmic auditory stimulation (2006) (32)
- Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2). (2003) (32)
- Transdermal rotigotine in advanced Parkinson’s disease: a randomized, double-blind, placebo-controlled trial (2014) (31)
- Colocalization of Bcl-2 and 4-hydroxynonenal modified proteins in microglial cells and neurons of rat brain following transient focal ischemia (1998) (30)
- Bell's palsy-induced blepharospasm (2002) (30)
- Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson’s disease (2005) (30)
- Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier (2007) (30)
- Efficacy and Safety of Extended- Versus Immediate-Release Pramipexole in Japanese Patients With Advanced and L-dopa–Undertreated Parkinson Disease: A Double-Blind, Randomized Trial (2012) (30)
- Twenty years since the discovery of the parkin gene (2017) (30)
- Synthetic peptide corresponding to 30 amino acids of the C-terminal of neuron-specific enolase promotes survival of neocortical neurons in culture. (1994) (29)
- Progress in familial Parkinson's disease. (2006) (28)
- Mutation analyses in amyotrophic lateral sclerosis/parkinsonism–dementia complex of the Kii peninsula, Japan (2008) (28)
- An immuno-histochemical study of ferritin in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys (1996) (27)
- Dominant‐negative effect of mutant valosin‐containing protein in aggresome formation (2006) (27)
- Positive immunoreactivity for vesicular monoamine transporter 2 in Lewy bodies and Lewy neurites in substantia nigra (2006) (27)
- Familial hemifacial spasm: report of cases and review of literature (2002) (27)
- [Progress in Parkinson's disease]. (2004) (26)
- Myoclonic tremulous movements in multiple system atrophy are a form of cortical myoclonus (2005) (26)
- Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture (1997) (25)
- Long-term safety and sustained efficacy of extended-release pramipexole in early and advanced Parkinson's disease (2014) (25)
- Transdermal rotigotine in early stage Parkinson's disease: A randomized, double‐blind, placebo‐controlled trial (2013) (25)
- Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain. (1995) (25)
- Superoxide dismutase activity in early stages of development in normal and dystrophic chickens. (1984) (25)
- Patient‐reported convenience of once‐daily versus three‐times‐daily dosing during long‐term studies of pramipexole in early and advanced Parkinson’s disease (2013) (24)
- Familial Parkinson’s disease: a hint to elucidate the mechanisms of nigral degeneration (2003) (24)
- Statistical parametric mapping of immunopositive cell density (2006) (24)
- Alpha-synuclein overexpression model. (2006) (24)
- Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice. (2004) (24)
- The parkin gene S/N167 polymorphism in Australian Parkinson's disease patients and controls. (2001) (24)
- Potential of Neuroprotective Therapy in Parkinson’s Disease (1994) (24)
- Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice (2004) (24)
- Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease. (2000) (23)
- Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system (1997) (23)
- Recent Research Progress in and Future Perspective on Treatment of Parkinson's Disease (2014) (23)
- Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains (2009) (22)
- Long-term treatment of Parkinson’s disease with levodopa and other adjunctive drugs (2017) (22)
- Golden mean to longevity: Rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease (2002) (22)
- Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain (1990) (22)
- Adeno-associated virus-mediated antiapoptotic gene delivery: in vivo gene therapy for neurological disorders. (2002) (22)
- Contrasting genotypes of the tau gene in two phenotypically distinct patients with P301L mutation of frontotemporal dementia and parkinsonism linked to chromosome 17 (2002) (21)
- Effects of bromocriptine on Parkinsonism A nation‐wide collaborative double‐blind study (1985) (21)
- Evaluation of the somatosensory evoked blink response in patients with neurological disorders. (1996) (21)
- Dopaminergic Neurotoxins, MPTP and MPP+, Inhibit Activity of Mitochondrial NADH-Ubiquinone Oxidoreductase (1986) (21)
- LRRK2 P755L variant in sporadic Parkinson's disease (2008) (21)
- Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease (2014) (21)
- Genetics of Parkinson's disease. (1999) (20)
- Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease. (2003) (20)
- Apoptosis in neurodegenerative disorders. (1997) (20)
- Hoarseness due to bilateral vocal cord paralysis as an initial manifestation of familial amyotrophic lateral sclerosis (2005) (20)
- Ectopic expression of α‐synuclein affects the migration of neural stem cells in mouse subventricular zone (2010) (20)
- Genetic and environmental factors in the pathogenesis of Parkinson's disease. (1999) (19)
- Relationship between Parkinson disease with dementia and dementia with Lewy bodies. (2005) (19)
- An analysis of the ultrastructural findings in infantile neuroaxonal dystrophy (Seitelberger's disease) (1974) (19)
- Serum creatine kinase is elevated in patients with Parkinson's disease: a case controlled study. (2003) (19)
- A Randomized Double-Blind Placebo-Controlled Phase III Trial of Selegiline Monotherapy for Early Parkinson Disease (2017) (19)
- α-Synuclein overexpression model (2006) (19)
- Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease (2008) (19)
- Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice (2011) (18)
- Pseudo-autosomal dominant inheritance of PARK2: two families with parkin gene mutations (2003) (18)
- An apparently sporadic case with parkin gene mutation in a Korean woman. (2001) (18)
- Genotype–phenotype correlation: Familial Parkinson disease (2003) (18)
- [Validation of the Japanese version of the Parkinson's Disease Questionnaire]. (2003) (17)
- Developmental changes in the expression of parkin and UbcR7, a parkin‐interacting and ubiquitin‐conjugating enzyme, in rat brain (2001) (17)
- Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase activities in early stages of development in dystrophic chickens (1985) (17)
- Mitochondrial energy crisis in Parkinson's disease. (1993) (17)
- Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain (2006) (16)
- Familial Parkinsonism with Apathy, Depression and Central Hypoventilation (Perry’s Syndrome) (2002) (16)
- Neurosarcoidosis Associated with Interferon Therapy (2001) (16)
- The L-DOPA story - an early Japanese contribution (2000) (15)
- Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. (2005) (15)
- EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population. (2014) (15)
- Parkin gene therapy for α-synucleinopathy: A rat model of Parkinson's disease (2006) (15)
- Characterization of multimetric variants of ubiquitin carboxyl-terminal hydrolase L1 in water by small-angle neutron scattering. (2006) (15)
- Analysis of eighteen deletion breakpoints in the parkin gene. (2009) (15)
- An Autopsy Case of Schilder’s Variant of Multiple Sclerosis (Schilder’s Disease) (2006) (14)
- Tau accumulation in a patient with pallidonigroluysian atrophy (2001) (14)
- [Excessive daytime sleepiness and low CSF orexin-A/hypocretin-I levels in a patient with probable progressive supranuclear palsy]. (2003) (14)
- Inhibition of ATP synthesis by 1-methyl-4-phenylpyridinium ion (MPP+) in mouse brain in vitro and in vivo. (1990) (13)
- Capgras syndrome in Parkinson's disease (2001) (13)
- Clinical and genetic studies on familial parkinsonism: The first report on a parkin gene mutation in a Taiwanese family (2001) (13)
- Mutation analysis for DJ-1 in sporadic and familial parkinsonism: Screening strategy in parkinsonism (2009) (13)
- A new mutation in the GCH1 gene presents as early-onset Parkinsonism. (2009) (13)
- Phosphorylated IκBα is a component of Lewy body of Parkinson’s disease (2005) (12)
- Dopamine deficiency may lead to capgras syndrome in Parkinson's disease with dementia. (2010) (12)
- Rapid screening of ATP13A2 variant with high‐resolution melting analysis (2010) (12)
- Effect of long-term administration of 1,2,3,4-tetrahydroisoquinoline (TIQ) on striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) content in mice (1988) (12)
- Early Addition of Selegiline to L-Dopa Treatment is Beneficial for Patients With Parkinson Disease (2010) (12)
- Comprehensive mutational analysis of LRRK2 reveals variants supporting association with autosomal dominant Parkinson's disease (2011) (12)
- The isolation of neural stem cells from the olfactory bulb of Parkinson's disease model (2007) (12)
- Blepharospasm associated with multiple system atrophy: a case report and review of the literature. (2004) (12)
- Success rate, efficacy, and safety/tolerability of overnight switching from immediate‐ to extended‐release pramipexole in advanced Parkinson's disease (2013) (12)
- A multi‐center, double‐blind study on slow‐release bromocriptine in the treatment of Parkinson's disease (1991) (12)
- Nuclear localization of the 20S proteasome subunit in Parkinson's disease (2006) (12)
- Effects of blockade of metabotropic glutamate receptors in the subthalamic nucleus on haloperidol-induced Parkinsonism in rats (2000) (12)
- Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations. (1999) (11)
- Practical Guidelines for the Drug Treatment of Parkinson’s Disease (1994) (11)
- Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse (1998) (11)
- Genetic aspects of Parkinson's disease. (1999) (11)
- Geographic and ethnic differences in frequencies of two polymorphisms (D/N394 and L/I272) of the parkin gene in sporadic Parkinson's disease. (2005) (11)
- Loss of DARPP-32 and calbindin in multiple system atrophy (2013) (11)
- Refinement of the gene locus for autosomal recessive juvenile parkinsonism (AR-JP) on chromosome 6q25.2-27 and identification of markers exhibiting linkage disequilibrium (1998) (11)
- A case of frontotemporal dementia with tau P301L mutation in the Far East (2000) (11)
- [Amyotrophic lateral sclerosis presented with alexia of kanji and word meaning aphasia]. (2002) (11)
- [A case of brainstem vascular malformation with isolated trochlear nerve palsy as the initial symptom]. (1991) (10)
- Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature. (2007) (10)
- Absence of linkage to 8q24 in a European family with familial adult myoclonic epilepsy (FAME). (2002) (10)
- I 2020 T mutant LRRK 2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT / GSK-3 β signaling pathway (2015) (10)
- Drug therapy of Parkinson's disease. An overview. (1992) (10)
- Effects of the globus pallidus lesion on the induction of c-Fos by dopaminergic drugs in the striatum possibly via pallidostriatal feedback loops (1998) (10)
- Structural Dimorphism in the Mitochondrial Targeting Sequence in the Human Manganese Superoxide Dismutase Gene: A Predictive Evidence for Conformational Change to Influence Mitochondrial Transport and a Study of Allelic Association in Parkinson's Disease: Volume226,Number 2 (1996), pages 561–565: (1996) (10)
- Mixed multiple system atrophy and progressive supranuclear palsy: a clinical and pathological report of one case (2014) (10)
- Glial localization of four‐repeat tau in atypical progressive supranuclear palsy (2004) (10)
- Postural effects of unilateral blockade of glutamatergic neurotransmission in the subthalamic nucleus on haloperidol-induced akinesia in rats (1998) (10)
- [Chronic inflammatory demyelinating polyneuropathy followed by systemic lupus erythematosus and Sjögren syndrome: a case report]. (2006) (10)
- Anticoagulant Therapy with a Selective Thrombin Inhibitor for Acute Cerebral Infarction: Usefulness of Coagulation Markers for Evaluation of Efficacy (2002) (10)
- Analyzer workshop on the treatment of Parkinson's disease. (1997) (9)
- Dystonic posturing and circling behaviors induced by dopaminergic agents in rats with unilateral globus pallidus lesions (1998) (9)
- A clue to the pathogenesis of dopa‐responsive dystonia (1995) (9)
- Gene therapy for Parkinson's disease. (2013) (9)
- Juvenile parkinsonism: ventricular CSF biopterin levels and clinical features (1992) (9)
- Mutation Analysis of the PINK 1 Gene in 391 Patients With Parkinson Disease (2008) (9)
- Propriospinal Negative Myoclonus (2001) (8)
- Phosphorylated IkappaBalpha is a component of Lewy body of Parkinson's disease. (2005) (8)
- Neurophysiological analysis of ataxia in capsular ataxic hemiparesis (1987) (8)
- Effects of donepezil dose escalation in Parkinson's patients with dementia receiving long‐term donepezil treatment: an exploratory study (2014) (8)
- Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins. (2006) (8)
- Clustering of Risk Factors Increases the Incidence of Echolucent Carotid Plaque in Stroke Patients (2006) (8)
- Where do we stand in the treatment of Parkinson's disease? (2007) (7)
- Role of mitrochondria in the etiology and pathogenesis of Parkinson's disease (1995) (7)
- No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients (2010) (7)
- Blind source separation and chaotic analysis of EEG for judgment of brain death (2001) (7)
- Specific detection of deleted mitochondrial DNA by in situ hybridization using a chimera probe. (1996) (7)
- Adeno-associated viral vector-mediated gene transduction in mesencephalic slice culture (2011) (7)
- [A long-term clinical effect of selegiline hydrochloride on Parkinson's disease]. (1996) (6)
- A large Japanese family with Machado–Joseph disease: clinical and genetic analysis (1999) (6)
- Autosomal Recessive Juvenile Parkinsonism (AR-JP): Genetic Diagnosis. (2001) (6)
- Pathological and biochemical studies on a case of Pick disease with severe white matter atrophy (2006) (6)
- Four-repeat tau-positive Pick body-like inclusions are distinct from classic Pick bodies (2005) (6)
- What Does Apoptosis Have To Do With Parkinson ’ s Disease ? (6)
- Effects of test H-reflex size on reciprocal inhibition in forearm muscles (1999) (5)
- More than 20 years of the discovery of Park2 (2020) (5)
- Bilateral Hypoglossal Nerve Involvement in Chronic Inflammatory Demyelinating Polyneuropathy (2004) (5)
- Globus pallidus lesions inhibit the induction of c-Fos by haloperidol in the basal ganglia output nuclei in rats (1998) (5)
- Parkin and Parkinson disease. (2012) (5)
- L-threo-3, 4-dihydroxyphenylserine Treatment for Dementia of Various Etiologies (1986) (5)
- Eyelid motor extinction (2001) (5)
- [Diagnostic criteria for brain death]. (1993) (5)
- [Molecular pathogenesis of familial Parkinson's disease]. (2000) (5)
- Myoclonic tremor in patients with parkinsonian‐type multiple system atrophy (2001) (5)
- Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation (2005) (4)
- Studies on the pathogenesis of Parkinson's disease in Japan. (1994) (4)
- A Histochemical Study of Iron and Ferritin in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Hemiparkinsonian Monkeys (1996) (4)
- Cortical myoclonus due to hypocalcemia 12 years after thyroidectomy (2006) (4)
- [Progress in the basic and clinical aspects of Parkinson's disease]. (2004) (4)
- Mitochondrial abnormalities in Parkinson's disease (1992) (4)
- Clinical manifestations and etiology in stroke patients with cancer: usefulness of coagulation and fibrinolytic markers (2006) (4)
- The unrelated communication interlude (UCI)--an automatic behavior phenomenon in Parkinson's disease. (2012) (4)
- No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients. (2010) (3)
- Mitochondrial energy crisis as a mechanism for nigral cell death (1991) (3)
- Long-Term Selegiline Monotherapy for the Treatment of Early Parkinson Disease (2019) (3)
- Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. (1993) (3)
- Ubiquitination of a Novel form of α-Synuclein by Parkin (2002) (3)
- [A case of neuralgic amyotrophy in the lower extremity (lumbosacral radiculoplexus neuropathy)]. (2007) (3)
- Cortical Reflex Action Myoclonus in Neurosyphilis (2001) (3)
- [Phase 2 clinical study of 123I-IBF, a dopamine D2 receptor imaging agent, to evaluate clinical efficacy and safety in Parkinson's disease and Parkinson syndromes]. (1999) (3)
- Second International Symposium on the Treatment of Parkinson's Disease (1998) (3)
- Impaired glucose tolerance and insulin resistance in patients with stroke (2006) (3)
- [An 81-year-old man with personality change, dementia, and gait disturbance with diffuse leukoaraiosis of the cerebral white matter]. (2006) (3)
- INCREASED DENSITY OF MITOCHONDRIA ISOLATED FROM THE SKELETAL MUSCLE OF A PATIENT WITH MITOCHONDRIAL MYOPATHY (1988) (3)
- [Japanese contribution to the understanding of frontotemporal dementia and parkinsonism linked to chromosome 17(FTDP-17)]. (2003) (3)
- [31P magnetic resonance spectroscopy(MRS) study in basal ganglia of patients with Parkinson's disease]. (1997) (3)
- [Parkin gene and its function; a key to understand nigral degeneration]. (1999) (2)
- [Concept and diagnostic criteria of Parkinson's disease and parkinsonism]. (1997) (2)
- [The role of oxygen free radicals in the aging of the brain]. (1990) (2)
- Isolated Deep Cerebral Venous Thrombosis: An Important Cause for Isolated Mental Impairment (2004) (2)
- Contents Vol. 45, 2001 (2001) (2)
- Pathophysiology of Parkinson’s Disease, Neurochemical Pathology: Other Neurotransmitters (2004) (2)
- Tetrahydrobiopterin Therapy for Juvenile Parkinsonism (1990) (2)
- 5th International Symposium on the Treatment of Parkinson's Disease (2001) (2)
- Dopamine cell death by a single genetic mechanism: phenotypic analysis and linkage study of autosomal recessive juvenile parkinsonism. (1999) (2)
- Interaction between parkin and alpha‐synuclein (2008) (2)
- Seventeenth Annual Symposia on Etiology, Pathogenesis, and Treatment of Parkinson's Disease and Other Movement Disorders (2003) (2)
- P2.159 Efflcacy and safety of once-daily (qd) pramipexole extended-release for advanced Parkinson's disease (2009) (2)
- Parkin binds the Rpn10 subunit of 26S proteasomes with the ubiquitin-like domain (2003) (2)
- Pseudoathetosis caused by migrated cervical disc. (2007) (2)
- Mortality Associated with Selegiline in Parkinson’s Disease (1997) (2)
- Piroheptine prevents loss of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced striatal loss of dopamine in mice. (1986) (2)
- [Studies on pathogenesis of muscular dystrophy: levels of thiobarbituric acid-reactive products in avian muscular dystrophy]. (1984) (2)
- [A patient with Hashimoto's encephalopathy showing subacute global cognitive dysfunction]. (2003) (1)
- Neuroimaging, Parkinson’s Disease (2010) (1)
- Dizziness and Vertigo (1992) (1)
- The Effect of Tetrahydroisoquinoline on the Mitochondrial Respiration (1990) (1)
- Pathogenesis of Parkinson’s disease: iron and mitochondrial DNA deletion (1993) (1)
- Evaluation of cerebral infarction using B-mode ultrasonic and doppler flowmeter. (1992) (1)
- Treatment of Parkinson's Disease after the Wearing Off Sets in (2019) (1)
- Familial Parkinson^|^apos;s disease based on the single gene defects (2001) (1)
- [A case of brachial plexus neuropathy who presented with acute paralysis of the hand after sleep]. (2002) (1)
- Colocalization of Parkin with α-Synuclein in the Lewy Bodies of Parkinson Disease (2002) (1)
- [Clinical characteristics and linkage analysis of autosomal recessive form of juvenile parkinsonism(AR-JP)]. (1997) (1)
- [Posterior leukoencephalopathy syndrome presenting with bilateral ataxie optique: a case report]. (2005) (1)
- Total Biopterin and Neopterin Levels in the Ventricular CSF Patients with Parkinson’s Disease (1990) (1)
- [A 59-year-old woman with personality change and abnormal behavior followed by amyotrophy and dementia]. (2005) (1)
- Corrigendum to “Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells” [Biochem. Biophys. Res. Commun. 332 (2005) 233–240] (2005) (1)
- Definition and Classification of Parkinsonian Drugs (2019) (1)
- Sustained efficacy and tolerability of pramipexole extended-release as adjunctive treatment in advanced Parkinson's disease (2010) (1)
- [Autosomal recessive juvenile parkinsonism: its pathogenesis is involved in the ubiquitin-proteasome pathway]. (2000) (1)
- P2.155 Simple overnight switching from immediate- to extended-release pramipexole in early Parkinson's disease at the same daily dosage (2009) (1)
- Generalized Convulsions After Consuming a Large Amount of Gingko Nuts (2001) (1)
- [Familial amyotrophic lateral sclerosis with rapid progression]. (2005) (1)
- Parkin as ubiquitin ligase (2001) (1)
- An update on the management of juvenile and young-onset Parkinson’s disease (2012) (1)
- Pathogenesis of Nigral Cell Death in Parkinson’s Disease (1995) (1)
- 1091 Possibility for neurogenesis in substantia nigra of Parkinsonian brain (2005) (1)
- Movement Disorders in Neurologic and Systemic Disease: Movement disorders in neoplastic brain disease (2014) (1)
- Parkin Mutations (Park 2) (2003) (1)
- Neurology and clinical neuroscience - a textbook of neurology (2007) (1)
- 2.265 LONG-TERM SAFETY AND SUSTAINED EFFICACY OF EXTENDED-RELEASE PRAMIPEXOLE IN EARLY AND ADVANCED PARKINSON'S DISEASE (2012) (0)
- Distribution of gamma amino butyric acid glutamate and aspartate in the thalamus of patients with basal ganglia disorders (1982) (0)
- Autosomal Recessive Juvenile Parkinsonism and the Ubiquitin Pathway (2002) (0)
- Comparisons among responses to pramipexole extended-release as adjunctive treatment in Japanese and non-Japanese studies of advanced Parkinson's disease (2010) (0)
- [Parkinson's disease]. (1994) (0)
- Author/Subject Indexes (1993) (0)
- Contents Vol. 22, 2006 (2006) (0)
- Small-angle neutron scattering (SANS) and dynamic light scattering (DLS) analyses of the initial aggregation process of tau by oxidative stress (2007) (0)
- [The Parkin gene and its product in AR-JP]. (1999) (0)
- Sustained off-time decrease in patients using pramipexole extended-release as adjunctive treatment in advanced Parkinson's disease (2010) (0)
- P2.153 Once-daily pramipexole extended-release (ER) demonstrated non-inferiority compared to immediate release (IR) tid dosing in early Parkinson's disease (2009) (0)
- P4-157 Accumulation of phosphorylated alpha-synuclein and tau in Alzheimer’s disease and dementia with Lewy bodies (2006) (0)
- [Japanese clinical statistical data of patients with parkinson's disease]. (1992) (0)
- Solution structure of ubiquitin-like domain of human parkin (2003) (0)
- [A study on long-term levodopa therapy in Parkinson's disease]. (1982) (0)
- Comparison between the efficacy of prostacyclin analogue (beraprost) with low-dose aspirin and aspirin alone to platelet aggregation and serum prostanoids (thromboxane B2 and 6-ketoPGF1.ALPHA.). (1995) (0)
- [Progress in studies of Parkinson's disease]. (2000) (0)
- Determination of platelet function in patients with cerebral infarction on antiplatelet therapy (1993) (0)
- Electrophysiological and other auxiliary investigations in patients with Parkinson’s disease dementia (2010) (0)
- [Discovery of the parkin gene; the gene for young onset autosomal recessive parkinsonism (AR)]. (2007) (0)
- Etiology, Pathogenesis, and Genetics of Parkinson’s Disease (2002) (0)
- Neurophysiology of blepharospasm in multiple system atrophy (2005) (0)
- 244. New Gene Therapy for Parkinson's Disease by Down Regulation of α-Synuclein (2006) (0)
- Chapter 13 – Neuroprotection in Parkinson's Disease (2005) (0)
- Meeting details (2005) (0)
- [Mitochondrial dysfunction in Parkinson's disease]. (2002) (0)
- The hallmark of Parkinson’s disease (PD) is a specific degeneration of dopaminergic neurons in the substantia nigra (SN). The cause of nigral dopaminergic neuronal cell death in PD and its underlying mechanisms (2017) (0)
- [Studies on Lewy bodies on their 100th year: a discussion]. (2012) (0)
- 2.263 PATIENT-REPORTED CONVENIENCE OF ONCE-DAILY VS TID DOSING DURING LONG-TERM STUDIES OF PRAMIPEXOLE IN EARLY AND ADVANCED PARKINSON'S DISEASE (2012) (0)
- Somatosensory evoked potentials in striatonigral degeneration and olivopontocerebellar atrophy (2005) (0)
- [A 76-year-old woman with personality change, dementia and parkinsonism]. (2005) (0)
- Advances in parkin gene therapy—A primate study (2007) (0)
- Proteine parkine utilisee comme ubiquitine ligase (2001) (0)
- P2.089 Efflcacy of pramipexole extended release (ER) and switching from pramipexole immediate release (IR) to ER in Japanese advanced PD patients (2009) (0)
- In memoriam, Professor Hirotaro Narabayashi (September 4, 1922–March 18, 2001) (2002) (0)
- Investigation of Carotid Stenosis and Blood Flow in Patients with Middle Cerebral Artery Thrombosis and Embolism by Duplex Ultrasonography (1993) (0)
- Up to what extent has the etiology of Parkinson^|^apos;s disease been elucidated? (1995) (0)
- The parkin protein-as a ubiquitin ligase (2001) (0)
- Subject Index Vol. 32, 1992 (1992) (0)
- [Late onset hemiparkinsonism-hemiatrophy syndrome: a case report]. (2005) (0)
- 949. AAV-Parkin Gene Therapy for Alpha-Synucleinopathy as Parkinson's Diseased Model (2005) (0)
- Chapter 2 Neurogenetics in Parkinson ’ s Disease (0)
- [Etiology and pathogenesis of parkinson's disease]. (1996) (0)
- Effect of Lymphocytapheresis on Steroid-Resistant Patients with Polymyositis(Neurological Disease,General Presentation) (1996) (0)
- S.27.04 Genetic aetiopathogenesis of Parkinson's disease (2004) (0)
- Subject Index Vol 38, Suppl. 1, 1997 (1997) (0)
- PS-5-4 The somatosensory evoked blink response: observation in neurological disorders (1995) (0)
- Inhibitory Effects of Endogenous Tetrahydroisoquinolines on Mitochondrial Respiration in Mouse Brain (1995) (0)
- P4-334 Chronic oral lithium administration attenuates motor disturbance through reducing tau phosphorylation in a tauopathy model mice (2006) (0)
- Review Inflammation and infection in Parkinson's disease (2006) (0)
- Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson's disease (vol 4, pg 195, 2002) (2002) (0)
- [Parkinson's disease; etiology and animal model]. (1991) (0)
- [Malignant migraine]. (2002) (0)
- Subject Index Vol. 45, 2001 (2001) (0)
- The cause of Parkinson disease is followed. (2005) (0)
- Parkinson's disease.Advance in diagnosis and treatments.2.Advance in pathosis and diagnosis.2.3 main syndromes in Parkinson's disease and the pathophysiology. (1994) (0)
- Evaluation ofthesomatosensory evokedblink responseinpatients withneurological disorders (1996) (0)
- Treatment of Parkinson's Disease: 1st Sandoz Symposium, Tokyo, October 1992 (1993) (0)
- Editorial Board (2007) (0)
- 1328 Neurotoxicities of MPP+ and tiq derivatives on dopaminergic neurons in ventral mesencephalic striatal co-culture (1993) (0)
- Apoptosis in MPP+-Treated Mesencephalic-Striatal Co-Culture and MPTP-Induced Hemiparkinsonian Monkeys (1996) (0)
- [Juvenile parkinsonism]. (2003) (0)
- [Progress in diagnosis and therapy for Parkinson's disease]. (2002) (0)
- A pharmacological analysis of circling behavior by chemical stimulation of pedunculopontine nucleus (1985) (0)
- Neurogenetics in Parkinson's Disease (2008) (0)
- Ubiquitin-Proteasome Pathway is a Key to Understanding of Nigral Degeneration in Autosomal Recessive Juvenile Parkinson’s Disease (2002) (0)
- [In pursuit of the causes for Parkinson disease]. (2005) (0)
- Dns or genes, which are involved in Parkinson's disease (1999) (0)
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue (2012) (0)
- Mitochondrial abnormalities in Parkinson^|^apos;s disease and MPTP-induced Parkinsonism (1990) (0)
- Mutant ubiquitin accumulate in CA1 pyramidal cells after transient global ischemia in gerbil (2005) (0)
- Molecular Biology of α-Synuclein (2002) (0)
- Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies (2015) (0)
- P3.132 Alpha-synuclein in stem cells (2009) (0)
- Erythropoietin regulated by hypoxia-inducible factor-1 and recombinant human erythropoietin protect cultured neurons from hypoxic and reoxygenic injury (2005) (0)
- Neuroprotective role of Fc gamma receptor in ischemia-reperfusion injury using Fc gamma receptor knockout mice (2005) (0)
- Correction (2004) (0)
- 16th Symposium on the Treatment of Parkinson's Disease, September 15, 2007, Tokyo, Japan. Preface. (2008) (0)
- [A long-term clinical effect of selegiline hydrochloride on Parkinson's disease]. (1994) (0)
- 1556 Differential expression of c-Fos immunoreactivity in the inferior olive under the harmaline-induced tremor in rats (1997) (0)
- [A 61-year-old man with rapidly progressing dementia and gait disturbance]. (1993) (0)
- 3.205 NECDIN PREVENTS LOSS OF DOPAMINERGIC NEURONS IN ANIMAL MODELS OF PARKINSON'S DISEASE (2012) (0)
- Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson's disease [Parkinsonism Relat Disord 6 (4) (2000) 195–197] (2002) (0)
- Chairman's remark (2003) (0)
- Quantitative Evaluation of Vocal Changes in Parkinson’s Disease: Intercorrelation among Voice Parameters and Monoamine Systems (1990) (0)
- [Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment]. (2002) (0)
- A case of transcortical motor aphasia caused by a frontal subcortical lesion (1992) (0)
- Subject Index Vol. 22, 2006 (2006) (0)
- A COMPREHENSIVE STUDY ON THE MECHANISM UNDERLYING THE PATHOGENESIS OF PARKINSON'S DISEASE AND ITS TREATMENT (1998) (0)
- 60-year-old female with SLE complicated by progressive ataxia (1991) (0)
- [The 3 major symptoms and their physiopathology in Parkinson disease]. (1994) (0)
- 1st Sandoz Symposium on the Treatment of Parkinson’s Disease, Vol. 33(suppl 1), 1993 (1993) (0)
- Parkinsonian Drugs: Guidelines for Japan (2020) (0)
- Etiology and pathogenesis of Parkinson^|^apos;s disease (2006) (0)
- [Effects and side effects of levodopa in parkinsonism - results of a collaborative study. (3) Side effects of levodopa]. (1976) (0)
- 59-year-old male with Parkinsonism died with malignant syndrome-like terminal (1991) (0)
- [Studies on pathogenesis of Parkinson's disease]. (2005) (0)
- [A patient with focal bi-parietal atrophy presenting motor clumsiness and cortical sensory loss]. (1998) (0)
- [Gene abnormalities in Parkinson disease]. (2005) (0)
- Complex I Deficiency in Parkinson’s Disease and MPTP-Induced Experimental Parkinsonism (1990) (0)
- Subject Index Vol. 38, Suppl. 2, 1997 (1997) (0)
- Parkin and Synuclein in Parkinson's Disease (2003) (0)
- 2K1545 Parkin binds the Rpn10 subunit of 26S proteasomes with the ubiquitin-like domain (2002) (0)
- Discussion: 8—11 A.M. - February 9, 1993 (1994) (0)
- [Effects of the "drug holiday" on problems of long-term levodopa therapy against Parkinson's disease]. (1984) (0)
- I2020T LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3beta signaling pathway (2016) (0)
- Parkinson Symptoms in Dementia with Lewy Bodies (2017) (0)
- a Chromosome 6q-Linked Parkinsonism (1998) (0)
- Anti-Apoptotic Therapy for Parkinson’s Disease: Overexpression of an APAF-1-Dominant-Negative Inhibitor Can Block MPTP Toxicity (2002) (0)
- Accumulation of 4-hydroxy-2-nonenal-modified proteins in the white matter damage in chronic cerebral hypo-perfusion rat mode (2005) (0)
- Progress in and Future Perspective on Treatment of Parkinson ’ s Disease (2014) (0)
- 242. Neuronal Specificity of α-Synuclein Toxicity and the Effect of Parkin Co-Expression in Primates (2006) (0)
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What Schools Are Affiliated With Yoshikuni Mizuno?
Yoshikuni Mizuno is affiliated with the following schools: