Yossef Av-Gay
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Biology
Why Is Yossef Av-Gay Influential?
(Suggest an Edit or Addition)According to Wikipedia, Yossef Av-Gay, born in 1961, is a Canadian microbiologist of Israeli origin. He is a professor of Infectious Diseases in the Faculty of Medicine at University of British Columbia, Vancouver, BC, Canada. He is also an associate member of the department of microbiology and immunology and holds an adjunct professorship at the medical school of Ben-Gurion University of the Negev, Israel.
Yossef Av-Gay's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA-Based Diagnostic Approaches for Identification of Burkholderia cepacia Complex, Burkholderia vietnamiensis, Burkholderia multivorans,Burkholderia stabilis, and Burkholderia cepacia Genomovars I and III (2000) (502)
- Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles. (2010) (420)
- The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. (2000) (376)
- Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+–ATPase to inhibit phagosome acidification (2011) (312)
- Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles. (2012) (276)
- Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B. (2008) (268)
- The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo (2004) (241)
- Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis (2015) (199)
- Mycothiol-Deficient Mycobacterium smegmatis Mutants Are Hypersensitive to Alkylating Agents, Free Radicals, and Antibiotics (2002) (193)
- Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis (2008) (162)
- A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase. (2000) (156)
- Species identification and phylogenetic relationships based on partial HSP60 gene sequences within the genus Staphylococcus. (1999) (151)
- Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. (2002) (128)
- Deletion of the Mycobacterium tuberculosis pknH Gene Confers a Higher Bacillary Load during the Chronic Phase of Infection in BALB/c Mice (2005) (125)
- Protein kinase and phosphatase signaling in Mycobacterium tuberculosis physiology and pathogenesis. (2010) (119)
- Synergistic Drug Combinations for Tuberculosis Therapy Identified by a Novel High-Throughput Screen (2011) (118)
- Expression and Characterization of the Mycobacterium tuberculosis Serine/Threonine Protein Kinase PknB (1999) (118)
- Mycobacterial manipulation of the host cell. (2005) (117)
- Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis (2012) (116)
- Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. (2016) (108)
- N-Acetyl-1-d-myo-Inosityl-2-Amino-2-Deoxy-α-d-Glucopyranoside Deacetylase (MshB) Is a Key Enzyme in Mycothiol Biosynthesis (2000) (105)
- Mycobacterium bovis BCG Attenuates Surface Expression of Mature Class II Molecules through IL-10-Dependent Inhibition of Cathepsin S1 (2005) (101)
- Convergence of Ser/Thr and Two-component Signaling to Coordinate Expression of the Dormancy Regulon in Mycobacterium tuberculosis* (2010) (99)
- The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence (2004) (98)
- Mycothiol-dependent proteins in actinomycetes. (2007) (96)
- Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis. (1999) (95)
- The Mycobacterial Transcriptional Regulator whiB7 Gene Links Redox Homeostasis and Intrinsic Antibiotic Resistance* (2011) (94)
- Gaseous nitric oxide bactericidal activity retained during intermittent high-dose short duration exposure. (2009) (94)
- Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity (2013) (86)
- Slow Release of Nitric Oxide from Charged Catheters and Its Effect on Biofilm Formation by Escherichia coli (2009) (86)
- The Glycosyltransferase Gene Encoding the Enzyme Catalyzing the First Step of Mycothiol Biosynthesis (mshA) (2003) (80)
- Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation (2007) (79)
- Mycobacterium tuberculosis PtkA is a novel protein tyrosine kinase whose substrate is PtpA. (2009) (75)
- Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth. (2010) (75)
- Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. (2002) (72)
- The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold* (2003) (70)
- Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD. (2006) (70)
- Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development. (2013) (70)
- Mycothiol‐dependent mycobacterial response to oxidative stress (2006) (69)
- MmpS4 promotes glycopeptidolipids biosynthesis and export in Mycobacterium smegmatis (2010) (66)
- Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis. (2003) (66)
- Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase. (2003) (65)
- Mycobacterium bovis Bacillus Calmette-Guérin Secreting Active Cathepsin S Stimulates Expression of Mature MHC Class II Molecules and Antigen Presentation in Human Macrophages1 (2007) (61)
- Thiol specific oxidative stress response in Mycobacteria. (2005) (57)
- Targeted Mutagenesis of the Mycobacterium smegmatis mca Gene, Encoding a Mycothiol-Dependent Detoxification Protein (2004) (56)
- Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis. (2007) (56)
- Microbial Protein-tyrosine Kinases* (2014) (54)
- Monitoring promoter activity and protein localization in Mycobacterium spp. using green fluorescent protein. (2001) (53)
- The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. (2009) (50)
- A protein kinase inhibitor as an antimycobacterial agent. (2001) (49)
- Antimicrobial, anti-inflammatory, antiparasitic, and cytotoxic activities of Galium mexicanum. (2011) (49)
- Cholesterol is accumulated by mycobacteria but its degradation is limited to non-pathogenic fast-growing mycobacteria. (2000) (49)
- Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase. (2007) (48)
- Mycobacterium tuberculosis Promotes Anti-apoptotic Activity of the Macrophage by PtpA Protein-dependent Dephosphorylation of Host GSK3α* (2014) (47)
- Precise Null Deletion Mutations of the Mycothiol Synthesis Genes Reveal Their Role in Isoniazid and Ethionamide Resistance in Mycobacterium smegmatis (2011) (47)
- Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages (2015) (47)
- Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme. (2006) (46)
- Streptomyces contain a 7.0 kDa cold shock like protein. (1992) (45)
- Comparative efficacy of commercially available and emerging antimicrobial urinary catheters against bacteriuria caused by E. coli in vitro. (2011) (45)
- Mycobacterium smegmatis biofilm formation and sliding motility are affected by the serine/threonine protein kinase PknF. (2008) (45)
- A phase I clinical study of inhaled nitric oxide in healthy adults. (2012) (43)
- Innate Protection of Mycobacterium smegmatis against the Antimicrobial Activity of Nitric Oxide Is Provided by Mycothiol (2007) (43)
- Antibacterial and Cytotoxic Activities of the Sesquiterpene Lactones Cnicin and Onopordopicrin (2011) (43)
- Mycobacterium avium subsp. paratuberculosis PtpA Is an Endogenous Tyrosine Phosphatase Secreted during Infection (2006) (43)
- Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis (2019) (42)
- Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity* (2015) (41)
- Signalling inhibitors against Mycobacterium tuberculosis--early days of a new therapeutic concept in tuberculosis. (2008) (41)
- Mycobacterium tuberculosis modulators of the macrophage's cellular events. (2012) (41)
- Screening of Compounds Toxicity against Human Monocytic cell line-THP-1 by Flow Cytometry (2004) (40)
- Kinome Analysis of Host Response to Mycobacterial Infection: a Novel Technique in Proteomics (2003) (38)
- Gaseous nitric oxide reduces influenza infectivity in vitro (2013) (37)
- Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: sequences, expression, and organization of the genes (1993) (35)
- Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages (2018) (33)
- Antimycobacterial activity of UDP-galactopyranose mutase inhibitors. (2010) (30)
- Coresistance to Isoniazid and Ethionamide Maps to Mycothiol Biosynthetic Genes in Mycobacterium bovis (2011) (29)
- Glutathione disulfide and S‐nitrosoglutathione detoxification by Mycobacterium tuberculosis thioredoxin system (2009) (29)
- Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in beta-lactam antibiotic biosynthesis (1993) (29)
- Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis (2013) (28)
- Phosphorylation control of protein tyrosine phosphatase A activity in Mycobacterium tuberculosis (2015) (28)
- Components of Eukaryotic-like Protein Signaling Pathways in Mycobacterium tuberculosis (1997) (27)
- Sydowiols A–C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii (2013) (27)
- Aminorifamycins and Sporalactams Produced in Culture by a Micromonospora sp. Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics. (2017) (26)
- Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis (2010) (26)
- Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria. (1998) (23)
- Antimicrobial activities of sesquiterpene lactones and inositol derivatives from Hymenoxys robusta. (2011) (23)
- Molecular cloning and biochemical characterization of a serine threonine protein kinase, PknL, from Mycobacterium tuberculosis. (2008) (21)
- Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery (2018) (18)
- Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence. (2017) (17)
- In vitro properties of antimicrobial bromotyrosine alkaloids. (2006) (17)
- Two-Component Systems, Protein Kinases, and Signal Transduction in Mycobacterium tuberculosis (2005) (16)
- Antimicrobial activity, cytotoxicity and inflammatory response of novel plastics embedded with silver nanoparticles. (2013) (16)
- High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies. (1991) (16)
- Development of a Liposome Formulation of Ethambutol (2004) (16)
- Nitric oxide charged catheters as a potential strategy for prevention of hospital acquired infections (2016) (16)
- DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular Mycobacteria (2020) (14)
- High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosis (2020) (14)
- Antimicrobial, Anti-Inflammatory, Antiparasitic, and Cytotoxic Activities of Laennecia confusa (2012) (13)
- System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis. (2017) (12)
- Phosphorylation of Mycobacterium tuberculosis protein tyrosine kinase A PtkA by Ser/Thr protein kinases. (2015) (12)
- Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms. (2015) (12)
- S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination (2019) (12)
- Chemical constituents, anti-inflammatory and antioxidant activities of bark extracts from Prunus tucumanensis Lillo (2013) (11)
- Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747. (2018) (11)
- BCG immunomodulation: From the ‘hygiene hypothesis’ to COVID-19 (2020) (11)
- From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis (2021) (10)
- Nitric oxide inhalations in bronchiolitis: A pilot, randomized, double‐blinded, controlled trial (2018) (10)
- Identification and characterization of a diamide sensitive mutant of Mycobacterium smegmatis. (2003) (9)
- Roles for phthiocerol dimycocerosate lipids in Mycobacterium tuberculosis pathogenesis. (2021) (9)
- THP-1 and Dictyostelium Infection Models for Screening and Characterization of Anti-Mycobacterium abscessus Hit Compounds (2019) (9)
- A MymA bioactivated thioalkyl-benzoxazole prodrug family active against Mycobacterium tuberculosis. (2020) (9)
- New Era of TB Drug Discovery and Its Impact on Disease Management (2016) (7)
- Prospects for TB Therapeutics Targeting Mycobacterium tuberculosis Phosphosignaling Networks (2011) (5)
- Uncontrolled Release of Harmful Microorganisms (1999) (5)
- Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation (2007) (4)
- Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis (2021) (4)
- Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1. (2021) (3)
- Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain (2017) (3)
- Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. (2018) (2)
- Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication (2022) (1)
- Apoptosis assessment in high-content and high-throughput screening assays. (2021) (1)
- CAT PETR: A Graphical User Interface for Differential Analysis of ProteinPhosphorylation Data (2023) (0)
- The ΔCysK2 mutant of Mycobacterium tuberculosis is sensitive to vancomycin associated with changes in cell wall phospholipid profile. (2022) (0)
- Mycobacterium tuberculosis dephosphorylation of human GSK3α (2015) (0)
- Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis (2022) (0)
- Intracellular Drug Targets In Mycobacterium Tuberculosis Revealed By A Chemo-Genetic Approach (2021) (0)
- Mycobacteriumsmegmatis bio¢lmformationand slidingmotility area¡ected by the serine/threonineprotein kinasePknF (2007) (0)
- Insights into whiB 7 activation and action (2011) (0)
- Screening of diverse marine invertebrate extracts identified Lissoclinotoxin F, Discodermin B, and other anti-Mycobacterium tuberculosis active compounds (2022) (0)
- Biophysical Characterizat ion of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv 1747 Graphical (2018) (0)
- Backbone 1H, 13C, and 15N Chemical Shift Assignments for FHA-1 domain of Rv1747 from Mycobacterium tuberculosis (2018) (0)
- The Crystal Structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) (2003) (0)
- Whole blood RNA-seq demonstrates an increased host immune response in individuals with cystic fibrosis who develop nontuberculous mycobacterial pulmonary disease (2022) (0)
- Front Cover: Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis (ChemMedChem 6/2022) (2022) (0)
- Insights into whiB 7 activation and action 1 The mycobacterial transcriptional regulator whiB 7 links redox homeostasis and intrinsic antibiotic resistance (2011) (0)
- Cathepsin S through IL-10-Dependent Inhibition of Expression of Mature Class II Molecules BCG Attenuates Surface Mycobacterium bovis (2005) (0)
- Detection of the pathogenicity factor PtpA in Mycobacterium bovis BCG (2018) (0)
- Screening for modulators of pkng activity (2003) (0)
- Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages (2018) (0)
- Mycobacterium tuberculosis Infection of THP-1 Cells: A Model for High Content Analysis of Intracellular Growth and Drug Susceptibility. (2022) (0)
- Global Proteomic Analyses of Macrophage Response to Mycobacterium tuberculosis Infection (2017) (0)
- Polymeric Nanofibers Co-loaded with Fusidic Acid & Rifampicin for the Prevention of Implant Associated Infections (2012) (0)
- Fernandez Lab - Publications (2017) (0)
- Editorial: New Approaches Against Drug-Resistant M. tuberculosis (2021) (0)
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