Yuet W Kan

Q: What Schools Are Affiliated With Yuet W Kan

Yuet W Kan is affiliated with the following schools: University of Alabama, California Institute of Technology, Tufts University, Stanford University, Johns Hopkins University, University of California, San Francisco, Harvard University

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Yuet W Kan

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Electrical Engineering

#750

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Yuet W Kan

Computer Science

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#4612

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#838

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#850

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Engineering
Computer Science

Yuet W Kan's Degrees

PhD Electrical Engineering Stanford University

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Yuet W Kan's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. (1994) (1397)
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling (1985) (1224)
Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis* (2003) (754)
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen (2001) (740)
Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation. (1978) (712)
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. (1996) (621)
Nrf2 is essential for protection against acute pulmonary injury in mice. (1999) (584)
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte (2009) (542)
Rapid duplication and loss of genes coding for the alpha chains of hemoglobin. (1980) (516)
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. (1994) (430)
Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac (2014) (389)
Nrf2 Transcription Factor, a Novel Target of Keratinocyte Growth Factor Action Which Regulates Gene Expression and Inflammation in the Healing Skin Wound (2002) (380)
Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. (1993) (329)
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection (2014) (306)
ANTENATAL DIAGNOSIS OF SICKLE-CELL ANÆMIA BY D.N.A. ANALYSIS OF AMNIOTIC-FLUID CELLS (1978) (273)
Targeted disruption of the ubiquitous CNC‐bZIP transcription factor, Nrf‐1, results in anemia and embryonic lethality in mice (1998) (263)
Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood (1996) (258)
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. (2005) (249)
Impaired liver regeneration in Nrf2 knockout mice: role of ROS‐mediated insulin/IGF‐1 resistance (2008) (248)
beta 0 thalassemia, a nonsense mutation in man. (1979) (231)
Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice (2010) (228)
Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype. (1980) (222)
Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice (2010) (216)
High-resolution chromosome sorting and DNA spot-blot analysis assign McArdle's syndrome to chromosome 11. (1984) (212)
Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases (2009) (210)
Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduc (2004) (210)
Transcription Factor Nrf2 Protects the Brain From Damage Produced by Intracerebral Hemorrhage (2007) (205)
Concurrent Sickle-Cell Anemia and α-Thalassemia: Effect on Severity of Anemia (1982) (201)
Triplicated alpha-globin loci in humans. (1980) (193)
A sensitive new prenatal test for sickle-cell anemia. (1982) (190)
The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis (2008) (179)
Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats (2003) (178)
The CNC Basic Leucine Zipper Factor, Nrf1, Is Essential for Cell Survival in Response to Oxidative Stress-inducing Agents (1999) (178)
Molecular cloning of protein 4.1, a major structural element of the human erythrocyte membrane skeleton. (1986) (176)
Detection of sickle cell anaemia and thalassaemias (1987) (174)
Globin chain synthesis in the alpha thalassemia syndromes. (1968) (171)
Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart. (2000) (171)
Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA. (1985) (168)
Rapid and simultaneous typing of hemoglobin S, hemoglobin C, and seven Mediterranean beta-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily. (1993) (165)
Polymorphism of DNA Sequence in the β-Globin Gene Region (1980) (162)
Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis) (1974) (159)
Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart (2011) (158)
beta zero thalassemia in Sardinia is caused by a nonsense mutation. (1981) (153)
cDNA sequence for human erythrocyte ankyrin. (1990) (150)
Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia (2016) (144)
Homology and concerted evolution at the α1 and α2 loci of human α-globin (1981) (142)
Tissue- and development-specific alternative RNA splicing regulates expression of multiple isoforms of erythroid membrane protein 4.1. (1991) (141)
Deletion of α-globin genes in haemoglobin-H disease demonstrates multiple α-globin structural loci (1975) (140)
Evolution of the hemoglobin S and C genes in world populations. (1980) (139)
Ligand-directed retroviral targeting of human breast cancer cells. (1995) (136)
Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice. (1993) (136)
Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model (2002) (135)
Identification of a nondeletion defect in α-thalassemia. (1977) (133)
Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes. (1979) (133)
hMAF, a Small Human Transcription Factor That Heterodimerizes Specifically with Nrf1 and Nrf2* (1997) (125)
Isolation of cDNA encoding the human NF-E2 protein. (1993) (123)
Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. (2004) (118)
Cloning of a cDNA for steroid sulfatase: frequent occurrence of gene deletions in patients with recessive X chromosome-linked ichthyosis. (1987) (116)
Construction of a functional human suppressor tRNA gene: an approach to gene therapy for β-thalassaemia (1982) (116)
Multiple protein 4.1 isoforms produced by alternative splicing in human erythroid cells. (1988) (113)
Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa. (1986) (111)
Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts. (2004) (111)
The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis (1987) (111)
The prevention of thalassemia. (2013) (110)
Initiation codon mutation as a cause of alpha thalassemia. (1984) (109)
Versatile cosmid vectors for the isolation, expression, and rescue of gene sequences: studies with the human alpha-globin gene cluster. (1983) (107)
Mild thalassemia: the result of interactions of alpha and beta thalassemia genes. (1970) (107)
Prenatal diagnosis of α-thalassemia: clinical application of molecular hybridization. (1976) (105)
The effect of adeno-associated virus mediated brain derived neurotrophic factor in an animal model of neurogenic impotence. (2001) (104)
Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia. (1982) (104)
Nrf2 Induces Interleukin-6 (IL-6) Expression via an Antioxidant Response Element within the IL-6 Promoter* (2010) (103)
Nrf2 in health and disease: current and future clinical implications. (2015) (103)
Accelerated Ovarian Failure Induced by 4-Vinyl Cyclohexene Diepoxide in Nrf2 Null Mice (2006) (101)
Differentiation of the mRNA transcripts originating from the alpha 1- and alpha 2-globin loci in normals and alpha-thalassemics. (1981) (101)
Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type 1: epidemiology and molecular analysis. (1992) (101)
Neuronal sensitivity to kainic acid is dependent on the Nrf2‐mediated actions of the antioxidant response element (2006) (100)
Globin structural mutant α125Leu→Pro is a novel cause of α-thalassaemia (1982) (99)
A RAPID SCREENING TEST FOR ANTENATAL SEX DETERMINATION (1984) (98)
A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy. (2001) (95)
Molecular characterization of beta-thalassemia in the Sardinian population. (1992) (95)
Reverse dot blot probes for the screening of β‐thalassernia mutationsin Asians and American blacks (1994) (93)
Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene. (1996) (92)
Differentiation-associated switches in protein 4.1 expression. Synthesis of multiple structural isoforms during normal human erythropoiesis. (1993) (92)
Antenatal Diagnosis of Sickle-Cell Anaemia by D. N. A. Analysis of Amniotic-Fluid Cells (1979) (92)
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site. (1989) (86)
Platelet glycoprotein IIb. Chromosomal localization and tissue expression. (1987) (84)
Synergistic enhancement of globin gene expression by activator protein-1-like proteins. (1990) (82)
Comparative chromosome mapping of a conserved homoeo box region in mouse and human (1985) (81)
Successful application of prenatal diagnosis in a pregnancy at risk for homozygous beta-thalassemia. (1975) (80)
A distant gene deletion affects beta-globin gene function in an atypical gamma delta beta-thalassemia. (1985) (80)
Detection of the sickle gene in the human fetus. Potential for intrauterine diagnosis of sickle-cell anemia. (1972) (80)
Two types of triplicated a -globin loci in humans (1981) (79)
Cloning and complete nucleotide sequence of human 5'-alpha-globin gene. (1980) (79)
Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice. (1992) (76)
Molecular basis of hereditary elliptocytosis due to protein 4.1 deficiency. (1986) (75)
Prenatal diagnosis of beta-thalassemia. Detection of a single nucleotide mutation in DNA. (1983) (73)
Antibodies to human fetal erythroid cells from a nonimmune phage antibody library (2001) (72)
Assignment of human beta-, gamma-, and delta-globin genes to the short arm of chromosome 11 by chromosome sorting and DNA restriction enzyme analysis. (1979) (71)
Genetic lesion in homozygous alpha thalassaemia (hydrops fetalis). (1974) (70)
PRENATAL DIAGNOSIS OF β-THALASSÆMIA AND SICKLE-CELL ANÆMIA Experience with 24 Cases (1977) (68)
A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression. (1992) (66)
Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes. (1998) (66)
Fetal blood-sampling in utero. (1974) (65)
Hydrops fetalis due to an unusual form of Hb H disease. (1985) (65)
Gamma-beta thalassemia: a cause of hemolytic disease of the newborn. (1972) (62)
Blood Cell‐Derived Induced Pluripotent Stem Cells Free of Reprogramming Factors Generated by Sendai Viral Vectors (2013) (62)
Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice. (1997) (61)
The same beta-globin gene mutation is present on nine different beta-thalassemia chromosomes in a Sardinian population. (1987) (57)
Demonstration of non-functional beta-globin mRNA in homozygous beta (0) thalassemia. (1975) (57)
Hb Bart's level in cord blood and deletions of alpha-globin genes. (1982) (56)
Evidence implicating heterozygous deletion of chromosome 7 in the pathogenesis of familial leukemia associated with monosomy 7. (1992) (55)
Construction of human chromosome 21-specific yeast artificial chromosomes. (1989) (54)
Beta thalassemia and translation of globin messenger RNA. (1971) (53)
Correction of the sickle cell mutation in embryonic stem cells. (2006) (53)
Combining angiogenic gene and stem cell therapies for myocardial infarction (2009) (53)
Nrf2 augments skeletal muscle regeneration after ischaemia–reperfusion injury (2014) (52)
Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb. (2003) (52)
AAV Serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect (2006) (51)
Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses. (1999) (50)
Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor (2018) (50)
Survival of a hydropic infant with homozygous α-thalassemia-1 (1986) (50)
Further observations on polycythemia in hepatocellular carcinoma. (1961) (50)
Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector. (1984) (48)
Alpha-thalassemia in two Mediterranean populations. (1982) (48)
Prenatal Diagnosis of Homozygous α-Thalassemia (1979) (48)
Relation of Beta to Gamma Synthesis During the First Trimester: An Approach to Prenatal Diagnosis of Thalassemia (1974) (47)
A novel beta-thalassemia frameshift mutation (codon 14/15), detectable by direct visualization of abnormal restriction fragment in amplified genomic DNA. (1988) (47)
PRENATAL DIAGNOSIS OF HEMOGLOBINOPATHIES * (1980) (46)
Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization (1995) (46)
Rapid prenatal diagnosis of beta thalassemia using DNA amplification and nonradioactive probes. (1989) (45)
Generation of induced pluripotent stem cells using site-specific integration with phage integrase (2010) (45)
alpha-Globin gene organisation in blacks precludes the severe form of alpha-thalassaemia. (1979) (45)
Reverse dot blot probes for the screening of beta-thalassemia mutations in Asians and American blacks. (1994) (45)
Multiple mutations produce delta beta 0 thalassemia in Sardinia. (1984) (44)
Molecular basis of beta thalassemia in south China. Strategy for DNA analysis. (1988) (44)
Spot-blot analysis of sorted chromosomes assigns a fructose intolerance disease locus to chromosome 9. (1985) (43)
Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase (1989) (43)
Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia. (1977) (43)
alpha-Thalassemia caused by an unstable alpha-globin mutant. (1983) (42)
In vivo aminoacylation of human and Xenopus suppressor tRNAs constructed by site-specific mutagenesis. (1987) (42)
Polymorphism of DNA sequence in the beta-globin gene region. Application to prenatal diagnosis of beta 0 thalassemia in Sardinia. (1980) (41)
An isoform-specific mutation in the protein 4.1 gene results in hereditary elliptocytosis and complete deficiency of protein 4.1 in erythrocytes but not in nonerythroid cells. (1993) (41)
Prenatal diagnosis of homozygous β-thalassæmia (1975) (41)
Alpha globin gene number: population and restriction endonuclease studies. (1980) (40)
TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs (2016) (40)
Nrf2 Deficiency Impairs Fracture Healing in Mice (2014) (39)
Globin Gene Switching (1996) (39)
Equal synthesis of - and -globin chains in erythroid precursors in heterozygous -thalassemia. (1972) (38)
Additive effect of AAV-mediated angiopoietin-1 and VEGF expression on the therapy of infarcted heart. (2009) (38)
Suppression of the nonsense mutation in homozygous β0 thalassaemia (1979) (37)
In utero diagnosis of: hemoglobinopathies. Hemoglobin synthesis in fetal red cells. (1974) (37)
Hemoglobin Long Island is caused by a single mutation (adenine to cytosine) resulting in a failure to cleave amino-terminal methionine. (1986) (36)
Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemia. (1998) (36)
Molecular basis of hemoglobin-H disease in the Mediterranean population (1979) (36)
Prenatal diagnosis of sickle-cell anemia. (1976) (35)
Localization of the gene for coagulation factor XIII a-chain to chromosome 6 and identification of sites of synthesis. (1987) (34)
Molecular Pathology of α‐Thalassemia (1985) (34)
Concentration of fetal red blood cells from a mixture of maternal and fetal blood by anti-i serum--an aid to prenatal diagnosis of hemoglobinopathies. (1974) (34)
Recombinant adeno-associated viral vector encoding human VEGF165 induces neomicrovessel formation in the adult mouse brain. (2006) (34)
Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin. (1981) (33)
The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes. (2005) (33)
Molecular characterization of erythrocyte glycophorin C variants. (1991) (32)
Silent delta-globin gene in Old World monkeys. (1980) (31)
A β-thalassemia ledon abolishes the same Mst II site as the sickle mutation (1983) (31)
Cosmid vectors for high efficiency DNA-mediated transformation and gene amplification in mammalian cells: studies with the human growth hormone gene. (1986) (31)
Hydrops fetalis with alpha thalassemia. (1967) (30)
Fetal gene therapy of α-thalassemia in a mouse model (2007) (30)
The untranslated regions of β-globin mRNA evolve at a functional rate in higher primates (1981) (29)
Haemoglobin Constant Spring Synthesis in Red Cell Precursors (1974) (29)
Molecular analysis of insertion/deletion mutations in protein 4.1 in elliptocytosis. II. Determination of molecular genetic origins of rearrangements. (1990) (28)
Prenatal diagnosis of hemoglobin disorders. (1977) (28)
Isolation and characterization of cDNA clones for human erythrocyte beta-spectrin. (1987) (27)
The nucleotide sequences of the untranslated 5' regions of human alpha- and beta-globin mRNAs. (1977) (27)
Two cloned β thalassemia genes are associated with amber mutations at codon 39 (1981) (27)
Effects of cyanate and 2,3-diphosphoglycerate on sickling. Relationship to oxygenation. (1973) (26)
Hemolytic disease of the newborn caused by a new deletion of the entire beta-globin cluster. (1983) (26)
Chromosomal localization of the human apolipoprotein B gene and detection of homologous RNA in monkey intestine. (1986) (26)
Human placental Na+,K+-ATPase alpha subunit: cDNA cloning, tissue expression, DNA polymorphism, and chromosomal localization. (1987) (25)
Delta +-thalassemia in Sardinia. (1983) (25)
Identification of a nondeletion defect in alpha-thalassemia. (1977) (25)
Diagnosis of Homozygous α-Thalassemia in Cultured Amniotic-Fluid Fibroblasts (1978) (25)
Modification of hemoglobin H disease by sickle trait. (1979) (25)
Signalling molecules involved in mouse bladder smooth muscle cellular differentiation. (2010) (24)
Different rates of mRNA translation balance the expression of the two human alpha-globin loci. (1982) (24)
A simple approach to prenatal diagnosis of beta-thalassemia in a geographic area where multiple mutations occur. (1988) (24)
Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene. (1993) (24)
The alpha-globin gene adjacent to the gene for HbQ-alpha 74 Asp replaced by His is deleted, but not that adjacent to the gene for HbG-alpha 30 Glu replaced by Gln; three-fourths of the alpha-globin genes are deleted in HbQ-alpha-thalassemia. (1979) (23)
Molecular basis of β thalassemia in South China (2004) (23)
Nrf2 Protects Against TWEAK-mediated Skeletal Muscle Wasting (2014) (23)
Isolation of a differentially regulated splicing isoform of human NF-E2. (1995) (23)
Prospects for research in hematologic disorders: sickle cell disease and thalassemia. (2001) (23)
Adeno-associated viral-mediated gene transfer to hepatoma: thymidine kinase/interleukin 2 is more effective in tumor killing in non-ganciclovir (GCV)-treated than in GCV-treated animals. (2000) (22)
Beta Thalassemia Trait: Detection at Birth (1968) (22)
Fetal blood sampling in midtrimester pregnancies. (1976) (21)
Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation. (2002) (20)
Prenatal diagnosis of beta-thalassaemia and sickle-cell anaemia. Experience with 24 cases. (1977) (19)
Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model. (2008) (19)
Toxic effects of high-dose cyanate administration in rodents. (1974) (19)
The inactive beta globin gene on a gamma delta beta thalassemia chromosome has a normal structure and functions normally in vitro. (1988) (19)
Molecular basis of hemoglobin-H disease in the Mediterranean population. (1979) (17)
Chromosomal Localization and Tissue Expression (1987) (17)
Characterization of a spontaneous mutation in beta-thalassemia associated with advanced paternal age. (1989) (17)
Dominant negative down-regulation of endotoxin-induced tumor necrosis factor α production by Lpsd/Ran (2000) (17)
Reticulocyte survival in sickle cell anemia: effect of cyanate. (1972) (16)
Mapping parathyroid hormone, β-globin, insulin, and LDH-A genes within the human chromosome 11 short arm by spot blotting sorted chromosomes (2004) (16)
Fetal gene therapy of alpha-thalassemia in a mouse model. (2007) (16)
[Antenatal diagnosis of sickle-cell anaemia by DNA analysis of amniotic fluid cells. A preliminary study in the French West-Indies (author's transl)]. (1981) (16)
Characteristics and distribution of β thalassemia haplotypes in South China (1986) (16)
Sequence of the 3'-noncoding and adjacent coding regions of human gamma-globin mRNA. (1978) (16)
Newborn screening by DNA analysis of dried blood spots (1989) (16)
Development of DNA analysis for human diseases. Sickle cell anemia and thalassemia as a paradigm. (1992) (15)
Prenatal diagnosis of alpha-thalassemia. Clinical application of molecular hybridization. (1976) (15)
The William Allan Memorial Award address: Thalassemia: molecular mechanism and detection. (1986) (14)
Alpha-thalassemia in blacks is due to gene deletion. (1979) (14)
Origin of “fused” glucose-6-phosphate dehydrogenase (1990) (14)
INTRAUTERINE DIAGNOSIS OF THALASSEMIA (1974) (13)
Survival of a hydropic infant with homozygous alpha-thalassemia-1. (1986) (13)
The nucleotide sequence of the 5′ untranslated region of human γ-globin mRNA (1978) (13)
Assignment of the human casein kinase II β-subunit gene to 6p12→p21 (1990) (12)
Stopping the Biologic Clock for Globin Gene Switching a (1990) (12)
Inhibition of hemoglobin synthesis by cyanate in vitro. (1974) (12)
Suppression of the nonsense mutation in homozygous beta 0 thalassaemia. (1979) (12)
Globin Gene Switching IN VIVO PROTEIN-DNA INTERACTIONS OF THE HUMAN (cid:98) -GLOBIN LOCUS IN ERYTHROID CELLS EXPRESSING THE FETAL OR THE ADULT GLOBIN GENE PROGRAM* (1996) (12)
Interplay between nuclear factor erythroid 2-related factor 2 and amphiregulin during mechanical ventilation. (2014) (12)
Adeno-associated viral vector-delivered hypoxia-inducible gene expression in ischemic hearts. (2007) (11)
of the mRNA Transcripts Originating from the al- and a2-Globin Loci in Normals and a-Thalassemics (1981) (11)
Amplification and expression of human alpha-globin genes in Chinese hamster ovary cells (1984) (11)
Two types of triplicated alpha-globin loci in humans. (1981) (11)
5' nucleotide sequence of a putative human placental alkaline phosphatase-like gene. (1988) (11)
ANTENATAL DIAGNOSIS OF SICKLE CELL ANAEMIA BY SENSITIVE DNA ASSAY (1982) (11)
Deletion of alpha-globin genes in haemoglobin-H disease demonstrates multiple alpha-globin structural loci. (1975) (11)
Expression and function of suppressor tRNA genes in mammalian cells. (1986) (10)
Human ferritin light chain gene sequences mapped to several sorted chromosomes (2004) (10)
Flow-sorting analysis of normal and abnormal human genomes. (1986) (10)
Demonstration of non-functional j3-globin mRNA in homozygous 3O-thalassemia (10)
In vivo protein-DNA interactions at the f8-globin gene locus (9)
The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis. (1987) (9)
Hemoglobin abnormalities: molecular and evolutionary studies. (1980) (9)
A sensitive test for prenatal diagnosis of sickle cell anemia: direct analysis of amniocyte DNA with MstII. (1982) (9)
A beta-thalassemia lesion abolishes the same Mst II site as the sickle mutation. (1983) (9)
Characteristics and distribution of beta thalassemia haplotypes in South China. (1986) (9)
Prenatal diagnosis of hemoglobin H disease. (1978) (9)
Thymic epithelial neoplasms in transgenic mice expressing SV40 T antigen under the control of an erythroid‐specific enhancer (1995) (8)
Characterization of β‐thalassemia mutations by denaturing gradient gel electrophoresis: patterns in the Mediterranean mutations (1994) (8)
Cellular regulation of fetal hemoglobin synthesis in man. Investigation of gamma and beta mRNA accumulation in clonal erythroid cultures initiated from erythroid progenitors derived from fetuses, neonates, and adult individuals. (1980) (8)
New application for DNA polymorphism. (1987) (8)
Molecular pathology of alpha-thalassemia. (1985) (8)
Organization of the zeta-alpha genes in Chinese. (1986) (8)
Prenatal diagnosis of homozygous beta-thalassaemia. (1975) (8)
Globin structural mutant alpha 125Leu leads to Pro is a novel cause of alpha-thalassaemia. (1982) (8)
A rapid and simple electrophoretic method for the detection of mutations involving small insertion or deletion: application to β-thalassemia (1991) (7)
Dominant negative down-regulation of endotoxin-induced tumor necrosis factor alpha production by Lps(d)/Ran. (2000) (7)
Male-enhanced expression and genetic conservation of a gene isolated with an anti-H-Y antibody. (1987) (7)
Assigning the polymorphic human insulin gene to the short arm of chromosome 11 by chromosome sorting (2004) (7)
High oxygen environment during pregnancy rescues sickle cell anemia mice from prenatal death. (2008) (7)
Long survival in sickle cell anemia (1982) (7)
Genetically-edited iPSCs derived from HIV-1 infected patients on therapy can give rise to immune cells resistant to HIV-1 infection. (2020) (7)
BamH I polymorphism in the Chinese: its potential usefulness in prenatal diagnosis of beta thalassaemia. (1984) (6)
Ferrara β0 thalassaemia caused by the β39 nonsense mutation (1984) (6)
A new protein synthesis factor from Escherichia coli. (1970) (6)
Organization of the a-Globin Genes in the Chinese a-Thalassemia Syndromes (2013) (6)
Tissue-specific targeting of retroviral vectors via ligand-receptor interactions (1995) (6)
beta (+)-Thalassaemia in the Po river delta region (northern Italy): genotype and beta globin synthesis. (1985) (6)
Induction of therapeutic levels of HbF in genome‐edited primary β039‐thalassaemia haematopoietic stem and progenitor cells (2020) (6)
Hemoglobin constant spring defined by specific oligonucleotide hybridization and hemoglobin D Punjab (β121→Gln) in a Batak Indonesian family (1988) (6)
Molecular biology of hemoglobin: its application to sickle cell anemia and thalassemia. (1991) (5)
MOLECULAR MECHANISMS IN α THALASSEMIA: RACIAL DIFFERENCES IN α‐GLOBIN GENE ORGANIZATION * (1980) (5)
Prenatal Diagnosis of Thalassemia in South China a (1990) (5)
SV40 T antigen directed by a powerful erythroid enhancer-promoter produced sarcomas and pancreatic tumors but not erythroid-specific tumors in transgenic mice. (1994) (5)
Beta thalassemia in Sardinia in the result of a nonsense mutation. (1981) (5)
Diagnosis of homozygous alpha-thalassemia in cultured amniotic-fluid fibroblasts. (1978) (5)
Prenatal diagnosis of homozygous alpha-thalassemia. (1979) (4)
Versatile cosmid vectors for the isolation , expression , and rescue of gene sequences : Studies with the human a-globin gene cluster ( human recombinant DNA library / selectable gene marker ) (4)
Assignment of the human casein kinase II beta-subunit gene to 6p12----p21. (1990) (4)
Regional gene mapping of human chromosomes purified by flow sorting. (1981) (4)
A Distant Gene Deletion Affects , 8-Globin Gene Function in an Atypical ' 6 y 5-Thalassemia (2013) (4)
Reversible Immortalization Enables Seamless Transdifferentiation of Primary Fibroblasts into Other Lineage Cells. (2016) (3)
Globin chain synthesis in haemoglobin New York (beta 113 replaced by glutamic acid). (1980) (3)
The Use of Direct Gene Analysis to Define β‐Thalassemia a (1990) (3)
Molecular Analysis of Insertion / Deletion Mutations in Protein 4 . 1 in Elliptocytosis I 1 (3)
The Molecular Defects of α-Thalassemia in the Filipino (1977) (3)
Genetically edited CD34+ cells derived from human iPS cells in vivo but not in vitro engraft and differentiate into HIV-resistant cells (2021) (3)
Two cloned beta thalassemia genes are associated with amber mutations at codon 39. (1981) (3)
The frequent occurrence of alpha thalassemia in blacks. (1979) (2)
Triplicated a-globin loci in humans (restriction endonuclease mapping/unequal crossing-over/ai thalassemia/polymorphism) (2016) (2)
Isolation of hybrid cell clones that contain deletion and non-deletion defects of alpha-thalassemia in man. (1980) (2)
Introductory Speech for Sir David Weatherall (2004) (2)
Development of Human Single-Chain Antibodies against SARS-Associated Coronavirus (2008) (2)
Authentic f-globin mRNA sequences in homozygous #0-thalassemia (2)
Molecular basis on HbH disease in the Mediterranean population (1980) (2)
CRISPR/Cas9-mediated gene deletion efficiently retards the progression of Philadelphia-positive acute lymphoblastic leukemia in a p210 BCR-ABL1T315I mutation mouse model (2020) (2)
The Molecular Genetics of Hemoglobin a (1989) (2)
EXPRESSION OF HUMAN α-Globin GENES IN HYBRID MOUSE ERYTHROLEUKEMIA CELLS (1980) (1)
Molecular mechanisms in alpha thalassemia: racial differences in alpha-globin gene organization. (1980) (1)
f 0 thalassemia , a nonsense mutation in man ( cDNA / reverse transcriptase / nucleic acid sequencing / amber mutation ) (1)
Yuet Wai Kan, MD: sickle cell and thalassemia pioneer. Interview by Tracy Hampton. (2006) (1)
Prenatal diagnosis by DNA analysis. (1982) (1)
Molecular characterization of b̃-thalassemia in Sardinian polulation (1992) (1)
Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector (0)
Prediction of severity of disease in homozygous β thalassemia (β thal) (1971) (0)
Targeting retroviral vectors to specific cells. Authors' reply (1995) (0)
Nonsense mutation as a cause of beta 0 thalassemia. (1980) (0)
Treatment of sickle cell anemia using the murine embryonic stem cell model (2007) (0)
cDNA sequence for human erythrocyte ankyrin ( skeletal protein / erythrocyte membrane ) (0)
Amplification of a SV40 T antigen transgene is associated with sarcomagenesis in mice. (1994) (0)
228. AAV Mediated Hypoxia-Inducible VEGF Expression and Neovascular Formation in Ischemic Pig Myocardium (2006) (0)
Thalassemia and abnormal hemoglobins. (1982) (0)
The nucleotide sequence of the 5' untranslated region of human gamma-globin mRNA. (1978) (0)
Hemoglobins in Development and Differentiation (1982) (0)
In vivo aminoacylation of human and Xenopus suppressor tRNAs constructed by site-specific mutagenesis (2003) (0)
alpha-Thalassemia caused by an unstable alpha-globin mutant (2018) (0)
Synergistic enhancement of globin gene expression by activator protein-i-like proteins (2004) (0)
The use of fetal red blood cells for the diagnosis of single gene disorders (1998) (0)
PRENATAL DIAGNOSIS OF HEMOCLOBIN-H DISEASE BY MOLECULAR HYBRIDIZATION (1977) (0)
Mechanisms of growth factor signaling in the control of cell growth and differentiation of vascular cells (2017) (0)
343. Vascular Endothelial Growth Factor Prevents Bone Marrow Derived-Mesenchymal Stem Cell Senescence In Vitro (2006) (0)
SUBCUTANEOUS VACCINATION WITH TUMOR CELLS PRODUCING IL-2 PREVENTS SUBSEQUENT DEVELOPMENT OF HEPATOCELLULAR CARCINOMA (1999) (0)
Molecular pathology of alpha-thalassemia. (1982) (0)
High Oxygen Environment during Pregnancy Rescues Sickle Cell Animia Mouse from Prenatal Death. (2006) (0)
The same 13-globin gene mutation is present on nine different fi-thalassemia chromosomes in a Sardinian population (polymorphic restriction endonuclease sites/haplotypes/oligonucleotide probes/crossing over/gene conversion) (0)
Response : Targeting Retroviral Vectors to Specific Cells (1995) (0)
The molecular defects of alpha-thalassemia in the Filipino. (1977) (0)
Chromosomal localization of the human apolipoprotein B gene and detection of homologous RNA in monkey intestine (molecular hybridization/sorted chromosomes/metaphase cells/tissue specificity) (2016) (0)
619. Co-Expression of AAV Mediated Angiopoietin-1 and VEGF in Ischemic Hearts Yield Leakage-Resistant Blood Vessels and Better Therapeutic Effect Than VEGF Alone (2005) (0)
926. Recombinant AAV Vectors Pseudotyped with Serotype-1 Capsid Mediates Early Onset of Gene Expression in Mouse Hearts (2005) (0)
Nucleic Acids Research (2003) (0)
A 36-base-pair core sequence of locus control region enhances retrovirally transferred human fl-globin gene expression (hypersensitive sites/NFE-2/AP-1/N2A vector/+,-2 and PA317 packaging cell lines) (2016) (0)
332. Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells (2016) (0)
192. Cardiac-Specific and Hypoxia-Responsive Vascular Endothelial Growth Factor Expression in Ischemic Hearts (2004) (0)
NONSENSE MUTATION AS A CAUSE OF β THALASSEMIA * (1980) (0)
Prenatal prediction of alpha-thalassemia phenotype by endonuclease mapping of parental DNA. (1982) (0)
Prospects for Research in Hematologic Disorders (2017) (0)
Amplification of the human alpha-globin gene enhances its expression. (1983) (0)
Abstract 1415: Tumorgenicity of Long-Term Cultured Mouse Bone Marrow-Derived Mesenchymal Stem Cells (2008) (0)
Lpsd y Ran of endotoxin-resistant C 3 H y HeJ mice is defective in mediating lipopolysaccharide endotoxin responses ( gene therapy y septic shock y GTPase y retrovirus y adenovirus ) (1999) (0)
Abstracts of papers presented at the 1994 meeting on gene therapy, September 21-25, 1994 (1994) (0)
Ferrara beta 0 thalassaemia caused by the beta 39 nonsense mutation. (1984) (0)
Polymorphism of DNA sequence adjacent to human f-globin structural gene : Relationship to sickle mutation ( sickle cell anemia / cDNA / restriction endonuclease / gene mapping ) (2004) (0)
Localization oftheGeneforCoagulation FactorXIII a-Chain toChromosome6andIdentification ofSites ofSynthesis (1987) (0)
Luang Eng Lie-Injo, M.D., Ph.D., D.T.M. & H. (1918–89) (1989) (0)

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