Yūichirō Kan'no
#191,195
Most Influential Person Now
Pharmaceutical scientist in Japan
Yūichirō Kan'no's AcademicInfluence.com Rankings
Yūichirō Kan'nomedical Degrees
Medical
#3896
World Rank
#4424
Historical Rank
Pharmacology
#512
World Rank
#574
Historical Rank
Yūichirō Kan'nochemistry Degrees
Chemistry
#5918
World Rank
#7187
Historical Rank
Organic Chemistry
#1103
World Rank
#1247
Historical Rank
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Medical Chemistry
Yūichirō Kan'no's Degrees
- PhD Pharmaceutical Sciences University of Tokyo
- Masters Pharmaceutical Sciences University of Tokyo
- Bachelors Pharmaceutical Sciences University of Tokyo
Why Is Yūichirō Kan'no Influential?
(Suggest an Edit or Addition)Yūichirō Kan'no's Published Works
Published Works
- Characterization of nuclear localization signals and cytoplasmic retention region in the nuclear receptor CAR. (2005) (40)
- A dihydrochalcone and several homoisoflavonoids from Polygonatum odoratum are activators of adenosine monophosphate-activated protein kinase. (2013) (40)
- Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells. (2012) (38)
- Primary structure and organ-specific expression of the rat aryl hydrocarbon receptor repressor gene. (2006) (33)
- Difference in nucleocytoplasmic shuttling sequences of rat and human constitutive active/androstane receptor. (2007) (32)
- A consecutive three alanine residue insertion mutant of human CAR: a novel CAR ligand screening system in HepG2 cells. (2010) (30)
- Diurnal difference in CAR mRNA expression (2004) (29)
- ent-Atisane diterpenoids from Euphorbia fischeriana inhibit mammosphere formation in MCF-7 cells (2015) (24)
- The inhibitory effect of aryl hydrocarbon receptor repressor (AhRR) on the growth of human breast cancer MCF-7 cells. (2006) (23)
- HER2 overexpression-mediated inflammatory signaling enhances mammosphere formation through up-regulation of aryl hydrocarbon receptor transcription. (2013) (23)
- Identification of intracellular localization signals and of mechanisms underlining the nucleocytoplasmic shuttling of human aryl hydrocarbon receptor repressor. (2007) (22)
- Suppressive effect of aryl hydrocarbon receptor repressor on transcriptional activity of estrogen receptor alpha by protein–protein interaction in stably and transiently expressing cell lines (2008) (22)
- Picrasidine G decreases viability of MDA-MB 468 EGFR-overexpressing triple-negative breast cancer cells through inhibition of EGFR/STAT3 signaling pathway. (2017) (21)
- Aryl hydrocarbon receptor counteracts pharmacological efficacy of doxorubicin via enhanced AKR1C3 expression in triple negative breast cancer cells. (2019) (20)
- Euphorins A–H: bioactive diterpenoids from Euphorbia fischeriana (2016) (20)
- Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. (2013) (20)
- Expression of constitutive androstane receptor splice variants in rat liver and lung and their functional properties. (2005) (19)
- Heregulin‐induced cell migration is promoted by aryl hydrocarbon receptor in HER2‐overexpressing breast cancer cells (2018) (17)
- DP97, a DEAD box DNA/RNA helicase, is a target gene-selective co-regulator of the constitutive androstane receptor. (2012) (17)
- TO901317, a potent LXR agonist, is an inverse agonist of CAR. (2013) (16)
- Picrasidine N Is a Subtype-Selective PPARβ/δ Agonist. (2016) (16)
- Alisol B 23-acetate from the rhizomes of Alisma orientale is a natural agonist of the human pregnane X receptor. (2017) (16)
- Identification of Picrasidine C as a Subtype-Selective PPARα Agonist. (2016) (15)
- Pd(II)-catalyzed ligand controlled synthesis of pyrazole-4-carboxylates and benzo[b]thiophene-3-carboxylates. (2014) (15)
- (17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor. (2011) (14)
- 5-aminoimidazole-4-carboxamide-1-beta-ribofuranoside (AICAR) prevents nuclear translocation of constitutive androstane receptor by AMP-activated protein kinase (AMPK) independent manner. (2010) (14)
- Dependence on the Microtubule Network and 90-kDa Heat Shock Protein of Phenobarbital-Induced Nuclear Translocation of the Rat Constitutive Androstane Receptor (2010) (14)
- Selective Androgen Receptor Modulator, YK11, Up-Regulates Osteoblastic Proliferation and Differentiation in MC3T3-E1 Cells. (2018) (13)
- Cycloartane-type triterpenes from Euphorbia fischeriana stimulate human CYP3A4 promoter activity. (2014) (12)
- Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor (2014) (11)
- The Differential Selectivity of Aryl Hydrocarbon Receptor (AHR) Agonists towards AHR-Dependent Suppression of Mammosphere Formation and Gene Transcription in Human Breast Cancer Cells. (2021) (10)
- Nigramide C Is a Natural Agonist of Human Pregnane X Receptor (2014) (10)
- The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems. (2010) (9)
- Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor (2021) (9)
- Antiepileptic Drug–Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator–Activated Receptor α and Peroxisome Proliferator–Activated Receptor γ Coactivator 1α–Dependent Gene Expression to Increase Blood Triglyceride Levels (2020) (8)
- Androgen receptor functions as a negative transcriptional regulator of DEPTOR, mTOR inhibitor. (2015) (8)
- Activation of the aryl hydrocarbon receptor by 3-methylcholanthrene, but not by indirubin, suppresses mammosphere formation via downregulation of CDC20 expression in breast cancer cells. (2021) (7)
- Role of the Defective Splicing of mRNA in the Lack of Pulmonary Expression of Constitutively Active Receptor in Rat (2003) (7)
- Identification of CAR/RXRα Hetero-dimer Binding Sites in the Human Genome by a Modified Yeast One-Hybrid Assay (2015) (6)
- Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR (2016) (6)
- Molecular Basis of the Intracellular Localization of the Constitutive Androstane Receptor (CAR) (2008) (5)
- Helix 12 stabilization contributes to basal transcriptional activity of PXR (2021) (5)
- Palladium(II) Catalyzed Cyclization-Carbonylation-Cyclization Coupling Reaction of (ortho-Alkynyl Phenyl) (Methoxymethyl) Sulfides Using Molecular Oxygen as the Terminal Oxidant (2016) (5)
- Protein arginine methyltransferase 5 (PRMT5) is a novel coactivator of constitutive androstane receptor (CAR). (2015) (5)
- Cell Cycle and Apoptosis Regulator 1, CCAR1, Regulates Enhancer-Dependent Nuclear Receptor CAR Transactivation (2018) (5)
- Biological Evaluation of the Pollution of the Tsurumi River with 7-Ethoxycoumarin O-Deethylase Activity Induced by River Sediment Extracts in HepG2 Cells (2003) (4)
- Polycyclic aromatic hydrocarbons induce CYP3A5 gene expression via aryl hydrocarbon receptor in HepG2 cells. (2021) (3)
- Improved Synthesis and Determination of the Biologically Active Diastereomer of YK11 (2020) (3)
- Tripartite Motif Containing 24 Acts as a Novel Coactivator of the Constitutive Active/Androstane Receptor (2018) (3)
- Identification of 10-dehydrooxyglycyuralin E as a selective human estrogen receptor alpha partial agonist. (2019) (2)
- Transcriptional Determination of Sexually Dimorphic Expression of Nuclear Receptor Constitutively Active Receptor (CAR) in Wistar Rats (2004) (2)
- Euphorins A–H: bioactive diterpenoids from Euphorbia fischeriana (2016) (2)
- Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance (2022) (1)
- Aryl Hydrocarbon Receptor Directly Regulates VTCN1 Gene Expression in MCF-7 Cells. (2022) (1)
- Chemical characterization of anemia-inducing aniline-related substances and their application to the construction of a decision tree-based anemia prediction model. (2021) (1)
- ent-Atisane diterpenoids from Euphorbia fischeriana inhibit mammosphere formation in MCF-7 cells (2015) (0)
- FDI-6, a FOXM1 inhibitor, activates the aryl hydrocarbon receptor and suppresses tumorsphere formation. (2022) (0)
- Exploration of nuclear receptor TR2 homodimer function by identification of its binding sites in human genome using modified Yeast One hybrid method (2015) (0)
- [Mechanism for subcellular localization of nuclear receptor CAR]. (2011) (0)
- Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor (2021) (0)
- BPB Reports (2018) (0)
- Development of a strategy to identify and evaluate direct and indirect activators of constitutive androstane receptor in rats. (2022) (0)
- Dependence on the microtubule network and heat shock protein 90 of phenobarbital-induced nuclear translocation of the rat constitutive androstane receptor (2009) (0)
- Involvement of the CYP1A1 inhibition-mediated activation of aryl hydrocarbon receptor in drug-induced hepatotoxicity. (2022) (0)
- Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453 cells. (2022) (0)
- Comparative Study of Different Epidermal Growth Factor Receptor (EGFR)-Tyrosine Kinase Inhibitors Affecting Lung Cancer Cell Lines Stably Overexpressing EGFR Mutations (2021) (0)
- Molecular Mechanism of the Effect of Gegen Qinlian Decoction on Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking (2022) (0)
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What Schools Are Affiliated With Yūichirō Kan'no?
Yūichirō Kan'no is affiliated with the following schools: