Yukiko Yamashita
American developmental biologist
Yukiko Yamashita's AcademicInfluence.com Rankings
Download Badge
Biology
Yukiko Yamashita's Degrees
- PhD Developmental Biology University of California, San Francisco
- Bachelors Biology Stanford University
Similar Degrees You Can Earn
Why Is Yukiko Yamashita Influential?
(Suggest an Edit or Addition)According to Wikipedia, Yukiko Yamashita is an American developmental biologist. She joined the Whitehead Institute in September 2020 and has been appointed a Professor of Biology at the Massachusetts Institute of Technology . She is the inaugural incumbent of the Susan Lindquist Chair for Women in Science at Whitehead Institute. She was previously a faculty member of the University of Michigan Life Sciences Institute and a professor in the Department of Cell and Developmental Biology at the University of Michigan Medical School. She was appointed an HHMI Investigator in 2013. In November 2013 she received a 5-year appointment as the James Playfair McMurrich Collegiate Professor of the Life Sciences at the University of Michigan Medical School. Her current research at the Whitehead Institute and MIT focuses on how germline immortality is maintained by germline stem cell behavior .
Yukiko Yamashita's Published Works
Published Works
- Orientation of Asymmetric Stem Cell Division by the APC Tumor Suppressor and Centrosome (2003) (754)
- Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division (2007) (520)
- Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover (2005) (467)
- Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. (1994) (327)
- Centrosome misorientation reduces stem cell division during ageing (2008) (323)
- Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy (2010) (316)
- Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle. (1998) (316)
- Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells (1999) (296)
- Regulation of Interneuron Function in the C. elegans Thermoregulatory Pathway by the ttx-3 LIM Homeobox Gene (1997) (266)
- Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis. (2005) (234)
- Signaling in stem cell niches: lessons from the Drosophila germline (2005) (209)
- 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway (1996) (174)
- A Misexpression Screen Reveals Effects of bag-of-marbles and TGFβ Class Signaling on the Drosophila Male Germ-Line Stem Cell Lineage (2004) (173)
- Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse. (2016) (169)
- Homologous DNA recombination in vertebrate cells (2001) (162)
- Nanotubes mediate niche-stem cell signaling in the Drosophila testis (2015) (158)
- Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation (2007) (157)
- UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. (2004) (151)
- Asymmetric stem cell division: precision for robustness. (2012) (142)
- RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells (2002) (140)
- Asymmetric centrosome behavior and the mechanisms of stem cell division (2008) (138)
- Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM (2005) (133)
- E-Cadherin Is Required for Centrosome and Spindle Orientation in Drosophila Male Germline Stem Cells (2010) (130)
- Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. (2002) (125)
- Polarity in stem cell division: asymmetric stem cell division in tissue homeostasis. (2010) (124)
- Chromosome-specific non-random sister chromatid segregation during stem cell division (2013) (124)
- Emerging mechanisms of asymmetric stem cell division (2018) (105)
- Aberrant mitosis in fission yeast mutants defective in fatty acid synthetase and acetyl CoA carboxylase (1996) (102)
- Centrosome-dependent asymmetric inheritance of the midbody ring in Drosophila germline stem cell division (2014) (102)
- Involvement of Vertebrate Polκ in Rad18-independent Postreplication Repair of UV Damage* 210 (2002) (89)
- Somatic cell reprogramming-free generation of genetically modified pigs (2016) (88)
- Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning (2011) (76)
- A conserved function for pericentromeric satellite DNA (2018) (76)
- Piwi Is Required in Multiple Cell Types to Control Germline Stem Cell Lineage Development in the Drosophila Ovary (2014) (75)
- Centrosome asymmetry and inheritance during animal development. (2012) (73)
- A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster (2016) (65)
- Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40. (2001) (60)
- Specialized Intercellular Communications via Cytonemes and Nanotubes. (2018) (57)
- Drosophila male germline stem cells do not asymmetrically segregate chromosome strands (2011) (54)
- Signaling by Cellular Protrusions: Keeping the Conversation Private. (2016) (53)
- Comparative Analysis of Satellite DNA in the Drosophila melanogaster Species Complex (2016) (53)
- Control of metaphase-anaphase progression by proteolysis: cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization. (1999) (49)
- Asymmetric Stem Cell Division and function of the Niche in the Drosophila Male Germ Line (2005) (49)
- Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells. (2012) (49)
- The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline (2015) (48)
- String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis (2011) (47)
- Fission yeast APC/cyclosome subunits, Cut20/Apc4 and Cut23/Apc8, in regulating metaphase‐anaphase progression and cellular stress responses (1999) (47)
- Cell adhesion in regulation of asymmetric stem cell division. (2010) (46)
- Fly meets yeast: checking the correct orientation of cell division. (2011) (46)
- The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells (2014) (43)
- The ins(ide) and outs(ide) of asymmetric stem cell division. (2016) (43)
- Stay Connected: A Germ Cell Strategy. (2017) (42)
- The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in Drosophila testis (2015) (42)
- Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells (2017) (41)
- Mechanisms of rDNA Copy Number Maintenance. (2019) (40)
- Subcellular Specialization and Organelle Behavior in Germ Cells (2017) (39)
- The modular mechanism of chromocenter formation in Drosophila (2018) (35)
- The centrosome and asymmetric cell division (2009) (33)
- Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis (2018) (32)
- Centrosome misorientation mediates slowing of the cell cycle under limited nutrient conditions in Drosophila male germline stem cells (2012) (29)
- Lineage Tracing Quantification Reveals Symmetric Stem Cell Division in Drosophila Male Germline Stem Cells (2013) (28)
- Germline stem cells: stems of the next generation. (2010) (26)
- Klp10A, a stem cell centrosome-enriched kinesin, balances asymmetries in Drosophila male germline stem cell division (2016) (25)
- The centrosome orientation checkpoint is germline stem cell specific and operates prior to the spindle assembly checkpoint in Drosophila testis (2015) (23)
- Regulation of asymmetric stem cell division: spindle orientation and the centrosome. (2009) (22)
- Germ cell connectivity enhances cell death in response to DNA damage in the Drosophila testis (2017) (22)
- mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis (2020) (20)
- The Hybrid Incompatibility Genes Lhr and Hmr Are Required for Sister Chromatid Detachment During Anaphase but Not for Centromere Function (2017) (20)
- Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells. (2007) (18)
- Asymmetric stem cell division and pathology: insights from Drosophila stem cell systems (2009) (17)
- DNA repair studies: experimental evidence in support of chicken DT40 cell line as a unique model. (2001) (16)
- Defective Satellite DNA Clustering into Chromocenters Underlies Hybrid Incompatibility in Drosophila (2021) (15)
- Function of Junk: Pericentromeric Satellite DNA in Chromosome Maintenance. (2017) (15)
- Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning (2011) (15)
- spict, a cyst cell-specific gene, regulates starvation-induced spermatogonial cell death in the Drosophila testis (2017) (15)
- A Misexpression Screen Reveals Effects of bagofmarbles bagofmarbles bagofmarbles ofmarbles ofmarbles and TGF Class Signaling on the Drosophila Male GermLine GermLine GermLine Stem Cell Lineage (2004) (12)
- Centrosome-centric view of asymmetric stem cell division (2020) (12)
- Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division (2017) (12)
- Keeping stem cells under control: New insights into the mechanisms that limit niche‐stem cell signaling within the reproductive system (2016) (11)
- DNA asymmetry in stem cells – immortal or mortal? (2013) (11)
- Nonrandom sister chromatid segregation of sex chromosomes in Drosophila male germline stem cells (2013) (11)
- Stem Cells and Aging: What's Next? (2015) (9)
- Regulation of Nucleolar Dominance in Drosophila melanogaster (2019) (9)
- Regulation of stem cell self-renewal versus differentiation by a support cell niche: Lessons from the Drosophila male germ line (2004) (9)
- Merlin is required for coordinating proliferation of two stem cell lineages in the Drosophila testis (2017) (9)
- Rheology of polystyrene solutions around the coil overlapping concentration: A phenomenological description of stresses in simple shear flow (2002) (8)
- The retrotransposon R2 maintains Drosophila ribosomal DNA repeats (2021) (6)
- Spindle positioning in the stem cell niche (2012) (6)
- Biased DNA segregation in Drosophila male germline stem cells. (2013) (6)
- Germline stem cell homeostasis. (2019) (6)
- Evaluation of the Asymmetric Division of Drosophila Male Germline Stem Cells. (2017) (5)
- Selfish stem cells compete with each other. (2008) (4)
- A new member of the spindle orientation club: mammalian intestinal stem cells. (2010) (4)
- me31B regulates stem cell homeostasis by preventing excess dedifferentiation in the Drosophila male germline (2021) (4)
- Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis (2020) (4)
- Stem cells and their niche in homeostasis/regeneration and disease (2014) (4)
- Cell biology of stem cells: studying stem cells at the level of cell biology and studying cell biology using stem cells (2018) (3)
- A Tale of Mother and Daughter (2010) (3)
- Reply to: Overlooked areas need attention for sound evaluation of DNA strand inheritance patterns in Drosophila male germline stem cells (2011) (3)
- The regulation and potential functions of intronic satellite DNA. (2022) (3)
- Non-random sister chromatid segregation mediates rDNA copy number maintenance in 1 Drosophila 2 3 (2021) (2)
- Localized mRNA translation mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis (2020) (2)
- Molding immortality from a plastic germline. (2021) (2)
- Stem cell niche signaling goes both ways. (2021) (2)
- Faculty Opinions recommendation of Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division. (2014) (2)
- Some Consequences of Having Too Little (2012) (2)
- Hierarchical Response Surface Methodology for Parameter Optimization: Efficiency of a Hierarchical RSM with a Hessian Matrix (2007) (2)
- A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage (2018) (2)
- Nonrandom template segregation: A way to break the symmetry of stem cells (2013) (2)
- Faculty Opinions recommendation of Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. (2008) (2)
- Asymmetric centrosome behavior in stem cell divisions (2012) (2)
- Author response: The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline (2015) (2)
- Stem Cell Niches in Drosophila (2009) (2)
- Nonrandom sister chromatid segregation of sex chromosomes in Drosophila male germline stem cells (2013) (1)
- Nonrandom sister chromatid segregation mediates rDNA copy number maintenance in Drosophila (2022) (1)
- Faculty Opinions recommendation of A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. (2010) (1)
- Faculty Opinions recommendation of Insulin levels control female germline stem cell maintenance via the niche in Drosophila. (2009) (1)
- Drosophila male germline stem cells do not asymmetrically segregate chromosome strands (2011) (1)
- Faculty Opinions recommendation of NUMB controls p53 tumour suppressor activity. (2008) (1)
- Author response: A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster (2016) (1)
- Ribosomal DNA and the rDNA-binding protein Indra mediate non-random sister chromatid segregation in Drosophila male germline stem cells (2018) (1)
- Ribosomal DNA Instability as a Potential Cause of Karyotype Evolution (2022) (1)
- Improved Hierarchical Parameter Optimization Technique - Application for a cardiac myocyte model (2006) (1)
- Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes (2023) (1)
- [Mechanisms of asymmetric stem cell division in the Drosophila male germ line]. (2007) (1)
- Heavy carrier doping by hydrogen in the spin-orbit coupled Mott insulator Sr2IrO4 (2021) (0)
- Homologous DNA recombina (2016) (0)
- Faculty Opinions recommendation of Primary cilia regulate mTORC1 activity and cell size through Lkb1. (2010) (0)
- Decision letter: Fatty acid β-oxidation is required for the differentiation of larval hematopoietic progenitors in Drosophila (2020) (0)
- A conserved function for pericentromeric satellite DNA 1 (2018) (0)
- Faculty Opinions recommendation of Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest. (2007) (0)
- Faculty Opinions recommendation of Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation. (2010) (0)
- Decision letter: PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN (2018) (0)
- Decision letter: Competition between kinesin-1 and myosin-V defines Drosophila posterior determination (2020) (0)
- Faculty Opinions recommendation of Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline. (2016) (0)
- Faculty Opinions recommendation of A Kinesin-14 Motor Activates Neocentromeres to Promote Meiotic Drive in Maize. (2018) (0)
- Faculty Opinions recommendation of Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. (2008) (0)
- Decision letter: Drosophila seminal sex peptide associates with rival as well as own sperm, providing SP function in polyandrous females (2020) (0)
- Faculty Opinions recommendation of Mitofusin 2 tethers endoplasmic reticulum to mitochondria. (2009) (0)
- Author response: A conserved function for pericentromeric satellite DNA (2018) (0)
- Author response: Klp10A, a stem cell centrosome-enriched kinesin, balances asymmetries in Drosophila male germline stem cell division (2016) (0)
- Fusome topology and inheritance during insect gametogenesis (2023) (0)
- Author response for "Centrosome-centric view of asymmetric stem cell division" (2020) (0)
- When the Family Treasure Is a Doormat. (2020) (0)
- Author response: Germ cell connectivity enhances cell death in response to DNA damage in the Drosophila testis (2017) (0)
- Author response: Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis (2020) (0)
- Faculty Opinions recommendation of sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. (2008) (0)
- Lhr and Hmr are required for sister chromatid detachment during anaphase but not for centromere function (2017) (0)
- Construction of Nbs1 knockout cell line using chicken DT40 (2000) (0)
- Decision letter: Region-specific regulation of stem cell-driven regeneration in tapeworms (2019) (0)
- Satellite DNA. (2022) (0)
- Derepression of Y-linked multicopy protamine-like genes interferes with sperm nuclear compaction in D. melanogaster (2023) (0)
- Lineage Tracing Quantification Reveals Symmetric Stem Cell Division in Drosophila Male Germline Stem Cells (2013) (0)
- Faculty Opinions recommendation of Lysosomal positioning coordinates cellular nutrient responses. (2011) (0)
- Decision letter: Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans (2019) (0)
- Evolution Repeats Itself in Building a Species Barrier. (2018) (0)
- Asymmetric stem cell division ensured by anaphase spindle repositioning (2009) (0)
- Faculty Opinions recommendation of Spindle asymmetry drives non-Mendelian chromosome segregation. (2017) (0)
- Faculty Opinions recommendation of An organelle-exclusion envelope assists mitosis and underlies distinct molecular crowding in the spindle region. (2015) (0)
- Faculty Opinions recommendation of Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. (2008) (0)
- Decision letter: Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle (2021) (0)
- Germ cell connectivity enhances cell death in response to DNA damage in Drosophila testis (2017) (0)
- Faculty Opinions recommendation of Cleavage of cohesin rings coordinates the separation of centrioles and chromatids. (2011) (0)
- Drosophila Males Use 5′-to-3′ Phased Biogenesis to Make Stellate-silencing piRNAs that Lack Homology to Maternally Deposited piRNA Guides (2022) (0)
- [Homologous DNA recombination is essential for the proliferation of vertebrate cells]. (2001) (0)
- Decision letter: Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis (2019) (0)
- Deregulation of Y-linked protamine-like genes in sex chromosome-biased spermatid demise (2022) (0)
- Editor's evaluation: Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle (2021) (0)
- Merlin is required for coordinating proliferation of two stem cell lineages in the Drosophila testis (2017) (0)
- Yukiko Yamashita: the centrosomes get there first. Interview by Caitlin Sedwick. (2013) (0)
- Author response: Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division (2018) (0)
- Decision letter: Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche (2020) (0)
- Decision letter: Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle (2019) (0)
- Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila (2018) (0)
- Decision letter: Cytoplasmic sharing through apical membrane remodeling (2020) (0)
- ASCB AWARD ESSAY A Tale of Mother and Daughter (2010) (0)
- Decision letter: RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster (2019) (0)
- Sex-specific topological differences in germline cell lineage trees (2022) (0)
- Faculty Opinions recommendation of LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. (2013) (0)
- Faculty Opinions recommendation of The adult Drosophila malpighian tubules are maintained by multipotent stem cells. (2007) (0)
- [Cellular mechanisms of asymmetric stem cell divisions in the stem cell niche]. (2006) (0)
- Cellular fingers take hold (2016) (0)
- Regulation of centrosome orientation in asymmetric division of the Drosophila male germ line stem cells (2010) (0)
- Stem Cells and Stem Cell Niches in Tissue Homeostasis: Lessons from the Expanding Stem Cell Populations of Drosophila (2009) (0)
- Investigating ChIP-seq derived candidate cis-regulatory regions in two different developmental systems (2010) (0)
- Cytokine receptor-Eb 1 interaction couples cell polarity and fate during asymmetric 1 cell division (2018) (0)
- Decision letter: Neuronal octopamine signaling regulates mating-induced germline stem cell increase in female Drosophila melanogaster (2020) (0)
- Detection of Hydrogen in Vacancies and Voids in Nickel by Positron Annihilation Lifetime Measurement (2008) (0)
- Decision letter: Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization (2019) (0)
This paper list is powered by the following services:
Other Resources About Yukiko Yamashita
What Schools Are Affiliated With Yukiko Yamashita?
Yukiko Yamashita is affiliated with the following schools: