Yuri Nikiforov
Researcher
Yuri Nikiforov 's AcademicInfluence.com Rankings

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Computer Science
Yuri Nikiforov 's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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Why Is Yuri Nikiforov Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Yuri Nikiforov is an American scientist who revolutionized the understanding of thyroid cancer, most recently winning a two-year battle in which the World Health Organization has agreed in 2017 to reclassify non-invasive thyroid tumors to non-cancerogenic liaisons. Those tumors typically have some, but not all, characteristics of cancer. The WHO has agreed to change the term for the tumors from Encapsulated Follicular Variant of Papillary Thyroid Carcinoma to Noninvasive Follicular Thyroid Neoplasm With Papillary-like Nuclear Features, or NIFTP. About 45,000 people a year are diagnosed with NIFTP in the world. The decision led to a change in protocol of medical treatment, which no longer required removal of the whole thyroid gland from such patients as well as ended the use of radioactive iodine, extending their life expectancy and quality of life. The patients still undergo surgery, in which their thyroid tumors are removed, typically with half, but not all, of the thyroid gland.
Yuri Nikiforov 's Published Works
Published Works
- 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. (2009) (7330)
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
- High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. (2003) (1488)
- Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors. (2016) (1065)
- BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. (2003) (1023)
- Molecular genetics and diagnosis of thyroid cancer (2011) (830)
- American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer. (2012) (711)
- RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. (2003) (680)
- Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. (1997) (633)
- MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. (2008) (581)
- Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples. (2011) (580)
- Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules. (2009) (528)
- Correlation Between Genetic Alterations and Microscopic Features, Clinical Manifestations, and Prognostic Characteristics of Thyroid Papillary Carcinomas (2006) (470)
- Poorly Differentiated Thyroid Carcinoma: The Turin Proposal for the Use of Uniform Diagnostic Criteria and an Algorithmic Diagnostic Approach (2007) (469)
- Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. (2000) (460)
- RET/PTC rearrangement in thyroid tumors (2002) (446)
- Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next‐generation sequencing assay (2014) (438)
- Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer. (2013) (419)
- Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. (2003) (411)
- Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. (2005) (411)
- Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis (2005) (379)
- Thyroid carcinoma: molecular pathways and therapeutic targets (2008) (351)
- Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. (2005) (346)
- PAX8-PPAR&ggr; Rearrangement in Thyroid Tumors: RT-PCR and Immunohistochemical Analyses (2002) (346)
- Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology (2015) (330)
- The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations. (2014) (324)
- Molecular diagnostics and predictors in thyroid cancer. (2009) (299)
- Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma. (2004) (278)
- Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis (2008) (271)
- Contribution of molecular testing to thyroid fine‐needle aspiration cytology of “follicular lesion of undetermined significance/atypia of undetermined significance” (2010) (254)
- RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis. (2007) (238)
- Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology (2018) (233)
- Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules (2018) (231)
- Molecular diagnostics of thyroid tumors. (2011) (225)
- Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer (2014) (223)
- Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. (1997) (221)
- MicroRNA Signature Distinguishes the Degree of Aggressiveness of Papillary Thyroid Carcinoma (2011) (221)
- ETV6‐NTRK3 is a common chromosomal rearrangement in radiation‐associated thyroid cancer (2014) (220)
- Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas (2004) (210)
- Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity. (2006) (207)
- Molecular analysis of thyroid tumors (2011) (197)
- Cytological features of "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" and their correlation with tumor histology. (2016) (190)
- Diagnostic pathology and molecular genetics of the thyroid (2012) (179)
- Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation. (2009) (171)
- Solid Variant of Papillary Thyroid Carcinoma: Incidence, Clinical–Pathologic Characteristics, Molecular Analysis, and Biologic Behavior (2001) (169)
- NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States (2016) (168)
- Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling (2011) (157)
- Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. (2004) (155)
- RAS mutations are the predominant molecular alteration in poorly differentiated thyroid carcinomas and bear prognostic impact. (2009) (148)
- 2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer. (2021) (141)
- Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes. (2018) (139)
- Cost Impact of Molecular Testing for Indeterminate Thyroid Nodule Fine-Needle Aspiration Biopsies (2012) (135)
- Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas (2009) (135)
- Delineation, Functional Validation, and Bioinformatic Evaluation of Gene Expression in Thyroid Follicular Carcinomas with the PAX8-PPARG Translocation (2006) (134)
- Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after the Chernobyl nuclear accident. (1996) (133)
- Thyroid lesions in children and adolescents after the Chernobyl disaster: implications for the study of radiation tumorigenesis. (1996) (131)
- Utilization of ancillary studies in thyroid fine needle aspirates: A synopsis of the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference (2008) (131)
- Increasing incidence of thyroid cancer: controversies explored (2013) (129)
- Prevalence of RET/PTC Rearrangements in Hashimoto's Thyroiditis and Papillary Thyroid Carcinomas (2002) (128)
- ROLE OF MOLECULAR MARKERS IN THYROID NODULE MANAGEMENT: THEN AND NOW. (2017) (126)
- Radiation-induced thyroid cancer: What we have learned from Chernobyl (2006) (124)
- Cytomorphological and molecular genetic findings in pediatric thyroid fine‐needle aspiration (2012) (123)
- RAS mutations in thyroid FNA specimens are highly predictive of predominantly low-risk follicular-pattern cancers. (2013) (122)
- Change in Diagnostic Criteria for Noninvasive Follicular Thyroid Neoplasm With Papillarylike Nuclear Features (2018) (122)
- MicroRNA Expression Profiles in Thyroid Tumors (2009) (122)
- Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation. (2005) (116)
- Alterations of the BRAF gene in thyroid tumors (2005) (114)
- Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma. (2013) (110)
- RET/PTC and PAX8/PPARγ chromosomal rearrangements in post‐Chernobyl thyroid cancer and their association with iodine‐131 radiation dose and other characteristics (2013) (109)
- Thyroid Transcription Factor-1, Thyroglobulin, Cytokeratin 7, and Cytokeratin 20 in Thyroid Neoplasms (2000) (109)
- A combined molecular‐pathologic score improves risk stratification of thyroid papillary microcarcinoma (2012) (108)
- MicroRNA expression array identifies novel diagnostic markers for conventional and oncocytic follicular thyroid carcinomas. (2013) (107)
- Overexpression of Insulin-Like Growth Factor-Binding Protein-4 (IGFBP-4) in Smooth Muscle Cells of Transgenic Mice through a Smooth Muscle α-Actin-IGFBP-4 Fusion Gene Induces Smooth Muscle Hypoplasia. (1998) (106)
- Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas (1999) (105)
- Proliferative activity of human thyroid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposure. (2006) (103)
- Noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP): A changing paradigm in thyroid surgical pathology and implications for thyroid cytopathology (2016) (103)
- Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: a review for pathologists (2018) (100)
- Thyroid Nodules (≥4 cm): Can Ultrasound and Cytology Reliably Exclude Cancer? (2014) (99)
- Molecular approaches to thyroid cancer diagnosis. (2014) (99)
- Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors. (2016) (96)
- Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients. (2015) (91)
- Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors. (2010) (91)
- New Strategies in Diagnosing Cancer in Thyroid Nodules: Impact of Molecular Markers (2013) (90)
- Pulmonary Langerhans cell histiocytosis: profiling of multifocal tumors using next-generation sequencing identifies concordant occurrence of BRAF V600E mutations. (2013) (87)
- DNA Breaks at Fragile Sites Generate Oncogenic RET/PTC Rearrangements in Human Thyroid Cells (2010) (86)
- Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies. (2010) (85)
- Interphase chromosome folding determines spatial proximity of genes participating in carcinogenic RET/PTC rearrangements (2006) (84)
- The Histopathology of BRAF-V600E–mutated Lung Adenocarcinoma (2008) (82)
- Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations. (2005) (82)
- MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights. (2014) (76)
- Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct. (2020) (74)
- HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma. (2007) (74)
- ret rearrangements in Japanese pediatric and adult papillary thyroid cancers. (1998) (73)
- A Novel Complex BRAF Mutation Detected in a Solid Variant of Papillary Thyroid Carcinoma (2009) (72)
- Next-Generation Sequencing Informatics: Challenges and Strategies for Implementation in a Clinical Environment. (2016) (69)
- PAX8/PPARγ rearrangement in thyroid nodules predicts follicular-pattern carcinomas, in particular the encapsulated follicular variant of papillary carcinoma. (2014) (69)
- Prevalence and phenotypic correlations of EIF1AX mutations in thyroid nodules. (2016) (69)
- BRAF mutation detection in indeterminate thyroid cytology specimens (2013) (68)
- Both BRAF V600E Mutation and Older Age (≥65 Years) are Associated with Recurrent Papillary Thyroid Cancer (2011) (67)
- A Clinical Algorithm for Fine-Needle Aspiration Molecular Testing Effectively Guides the Appropriate Extent of Initial Thyroidectomy (2014) (66)
- Poorly differentiated thyroid carcinoma of childhood and adolescence: A distinct entity characterized by DICER1 mutations (2020) (66)
- A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing. (2016) (62)
- Identification of a novel point mutation in the RET gene (Ala883Thr), which is associated with medullary thyroid carcinoma phenotype only in homozygous condition. (2004) (61)
- Protocol for the Examination of Specimens From Patients With Carcinomas of the Thyroid Gland (2009) (59)
- Consistency and reproducibility of next‐generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens (2017) (58)
- Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics (2014) (58)
- RET/PTC Rearrangement--a link between Hashimoto's thyroiditis and thyroid cancer...or not. (2006) (55)
- BRAF V600E Mutation Independently Predicts Central Compartment Lymph Node Metastasis in Patients with Papillary Thyroid Cancer (2012) (55)
- Molecular Analysis of Thyroid Tumors (2011) (55)
- Preoperative detection of RAS mutation may guide extent of thyroidectomy (2017) (54)
- Clinical and Morphologic Features of ETV6-NTRK3 Translocated Papillary Thyroid Carcinoma in an Adult Population Without Radiation Exposure (2017) (54)
- Regulation of p27Kip1 Protein Levels Contributes to Mitogenic Effects of the RET/PTC Kinase in Thyroid Carcinoma Cells (2004) (54)
- Follicular cell-derived thyroid cancer (2015) (53)
- Histopathologic and Clinical Characterization of Thyroid Tumors Carrying the BRAF(K601E) Mutation. (2016) (53)
- The evolving diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). (2018) (53)
- Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms. (2000) (52)
- Molecular Characterization of Sporadic Pediatric Thyroid Carcinoma with the DNA/RNA ThyroSeq v2 Next-Generation Sequencing Assay (2016) (51)
- Mechanisms of chromosomal rearrangements in solid tumors: The model of papillary thyroid carcinoma (2010) (50)
- Adequacy of surgeon-performed ultrasound-guided thyroid fine-needle aspiration biopsy (2008) (50)
- Is ionizing radiation responsible for the increasing incidence of thyroid cancer? (2010) (49)
- Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells (2012) (49)
- Can malignant thyroid nodules be distinguished from benign thyroid nodules in children and adolescents by clinical characteristics? A review of 89 pediatric patients with thyroid nodules. (2015) (48)
- Diagnosis and management of differentiated thyroid cancer using molecular biology (2013) (48)
- BRAF copy number gains in thyroid tumors detected by fluorescence In Situ hybridization (2005) (47)
- Suspicious ultrasound characteristics predict BRAF V600E-positive papillary thyroid carcinoma. (2012) (47)
- Clinical validation of the ThyroSeq v3 genomic classifier in thyroid nodules with indeterminate FNA cytology (2019) (47)
- Establishment of a non‐tumorigenic papillary thyroid cell line (FB‐2) carrying the RET/PTC1 rearrangement (2002) (46)
- THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer (2017) (45)
- Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (2017) (45)
- Changing the Cancer Diagnosis: The Case of Follicular Variant of Papillary Thyroid Cancer-Primum Non Nocere and NIFTP. (2016) (44)
- GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland. (2019) (44)
- Frequent loss of heterozygosity at chromosome 3p14.2–3p21 in human pancreatic islet cell tumours (1999) (43)
- Molecular and Histopathologic Characteristics of Multifocal Papillary Thyroid Carcinoma (2013) (42)
- Characteristics of follicular tumors and nonneoplastic thyroid lesions in children and adolescents exposed to radiation as a result of the chernobyl disaster (1995) (41)
- Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer. (2018) (40)
- Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer (2019) (40)
- The influence of the noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP) resection diagnosis on the false‐positive thyroid cytology rate relates to quality assurance thresholds and the application of NIFTP criteria (2017) (39)
- Comprar Diagnostic Pathology And Molecular Genetics Of The Thyroid. A Comprehensive Guide For Practicing Thyroid Pathology 2nd Ed. | Yuri E. Nikiforov | 9781451114553 | Lippincott Williams & Wilkins (2012) (39)
- Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP): Achieving Better Agreement By Refining Diagnostic Criteria (2018) (38)
- An International Interobserver Variability Reporting of the Nuclear Scoring Criteria to Diagnose Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: a Validation Study (2018) (38)
- Nodule size is an independent predictor of malignancy in mutation-negative nodules with follicular lesion of undetermined significance cytology. (2013) (38)
- Thyroid sclerosing mucoepidermoid carcinoma with eosinophilia: a clinicopathologic and molecular analysis of a distinct entity (2017) (37)
- Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon. (2002) (37)
- MicroRNA dysregulation in human thyroid cells following exposure to ionizing radiation. (2011) (37)
- Preoperative cytology with molecular analysis to help guide surgery for pediatric thyroid nodules. (2013) (35)
- Mutation in BRAF and Other Members of the MAPK Pathway in Papillary Thyroid Carcinoma in the Pediatric Population. (2016) (35)
- AHNS Series: Do you know your guidelines? AHNS Endocrine Section Consensus Statement: State‐of‐the‐art thyroid surgical recommendations in the era of noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (2018) (35)
- Neoadjuvant treatment of unresectable medullary thyroid cancer with sunitinib. (2010) (35)
- Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort (2015) (34)
- Prevalence of minisatellite and microsatellite instability in radiation-induced post-Chernobyl pediatric thyroid carcinomas (1998) (34)
- Benign call rate and molecular test result distribution of ThyroSeq v3 (2019) (34)
- RAS Mutation-Positive Follicular Variant of Papillary Thyroid Carcinoma Arising in a Struma Ovarii (2010) (33)
- Amiodarone-induced thyrotoxicosis and thyroid cancer: clinical, immunohistochemical, and molecular genetic studies of a case and review of the literature. (2004) (32)
- Erratum: American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer (Thyroid (2012) 22:11 (1104-1139)) (2012) (32)
- Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells (2009) (31)
- Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia. (1998) (30)
- Consistency and reproducibility of next‐generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens (2019) (29)
- Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: A report from the children's oncology group (2010) (28)
- Summary statement: utility of molecular marker testing in thyroid cancer. (2010) (28)
- Use of molecular biomarkers in FNA specimens to personalize treatment for thyroid surgery (2012) (28)
- SeqReporter: automating next-generation sequencing result interpretation and reporting workflow in a clinical laboratory. (2014) (28)
- Multiple Mutations Detected Preoperatively May Predict Aggressive Behavior of Papillary Thyroid Cancer and Guide Management--A Case Report. (2015) (27)
- Characterization of Thyroid Cancer Driven by Known and Novel ALK Fusions. (2019) (27)
- Noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP) in thyroid tumor classification (2018) (27)
- Pathologic Reporting of Tall-Cell Variant of Papillary Thyroid Cancer: Have We Reached a Consensus? (2017) (26)
- RET Rearrangements in Lung Adenocarcinoma and Radiation (2014) (26)
- Tumor-to-tumor Metastases to Follicular Variant of Papillary Thyroid Carcinoma: Histologic, Immunohistochemical, and Molecular Studies of Two Unusual Cases (2009) (25)
- Targeted mutation detection in breast cancer using MammaSeq™ (2018) (24)
- Ewing sarcoma of the thyroid: Report of 2 cases and review of the literature (2013) (24)
- DNA Topoisomerases Participate in Fragility of the Oncogene RET (2013) (24)
- Thyroid cancer in 2015: Molecular landscape of thyroid cancer continues to be deciphered (2016) (23)
- Chapter 7 – Thyroid and Parathyroid Glands (2009) (22)
- “Colloid‐Rich” follicular neoplasm/suspicious for follicular neoplasm thyroid fine‐needle aspiration specimens: Cytologic, histologic, and molecular basis for considering an alternate view (2013) (22)
- BRAF Kinase Activation via Chromosomal Rearrangement in Radiation-Induced and Sporadic Thyroid Cancer (2005) (21)
- THYROID CARCINOMA-ASSOCIATED GENETIC MUTATIONS ALSO OCCUR IN THYROID LYMPHOMAS (2012) (21)
- Cancer risk and clinicopathological characteristics of thyroid nodules harboring thyroid‐stimulating hormone receptor gene mutations (2018) (20)
- Editorial: anaplastic carcinoma of the thyroid--will aurora B light a path for treatment? (2005) (19)
- Pathomorphology of thyroid gland lesions associated with radiation exposure: the Chernobyl experience and review of the literature. (1999) (19)
- Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis. (2009) (18)
- Ramifications of New Terminology for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma-Reply. (2016) (17)
- Encapsulated Papillary Oncocytic Neoplasms of the Thyroid: Morphologic, Immunohistochemical, and Molecular Analysis of 18 Cases (2010) (17)
- Thyroid cytology smear slides: An untapped resource for ThyroSeq testing (2020) (17)
- Formation of carcinogenic chromosomal rearrangements in human thyroid cells after induction of double-strand DNA breaks by restriction endonucleases. (2012) (17)
- Loss of heterozygosity of selected tumor suppressor genes in parathyroid carcinoma. (2008) (17)
- Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma. (2019) (17)
- DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis. (2019) (17)
- Identification of Unique, Heterozygous Germline Mutation, STK11 (p.F354L), in a Child with an Encapsulated Follicular Variant of Papillary Thyroid Carcinoma within Six Months of Completing Treatment for Neuroblastoma (2015) (16)
- Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G₀-phase human cells (2013) (16)
- Intraoperative pathologic examination in the era of molecular testing for differentiated thyroid cancer. (2012) (15)
- Mutations of TSHR and TP53 Genes in an Aggressive Clear Cell Follicular Carcinoma of the Thyroid (2015) (15)
- Recent Developments in the Molecular Biology of the Thyroid (2010) (14)
- Risk Factors for Thyroid Cancer (1997) (14)
- Prevalence and spectrum of DICER1 mutations in adult-onset thyroid nodules with indeterminate cytology. (2021) (14)
- Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements (2018) (13)
- Follicular variant papillary thyroid carcinoma arising within an ovarian teratoma. (2007) (12)
- Risk assessment for distant metastasis in differentiated thyroid cancer using molecular profiling: A matched case‐control study (2021) (12)
- Targeted Next-Generation Sequencing Analysis of a Pendred Syndrome-Associated Thyroid Carcinoma (2016) (12)
- Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples (2020) (11)
- Clinical Implementation and Validation of Automated Human Genome Variation Society (HGVS) Nomenclature System for Next-Generation Sequencing-Based Assays for Cancer. (2018) (11)
- Frequency of close positioning of chromosomal loci detected by FRET correlates with their participation in carcinogenic rearrangements in human cells (2012) (11)
- GLIS rearrangements in thyroid nodules: A key to preoperative diagnosis of hyalinizing trabecular tumor (2019) (11)
- Molecular alterations in Hürthle cell nodules and preoperative cancer risk. (2021) (10)
- MiRNAs Are Involved in Tall Cell Morphology in Papillary Thyroid Carcinoma (2019) (10)
- Limitations of preoperative cytology for medullary thyroid cancer: Proposal for improved preoperative diagnosis for optimal initial medullary thyroid carcinoma specific surgery (2020) (10)
- Mouse Model of Poorly Differentiated Thyroid Carcinoma Driven by STRN-ALK Fusion. (2018) (10)
- American Head and Neck Society Endocrine Surgery Section and International Thyroid Oncology Group consensus statement on mutational testing in thyroid cancer: Defining advanced thyroid cancer and its targeted treatment (2022) (10)
- DNA fragile site breakage as a measure of chemical exposure and predictor of individual susceptibility to form oncogenic rearrangements (2017) (10)
- Clinicopathologic Characteristics of Thyroid Nodules Positive for the THADA-IGF2BP3 Fusion on Preoperative Molecular Analysis. (2021) (9)
- Nuclear Export of MicroRNA Precursors (2004) (9)
- Synchronous Independent Papillary Thyroid Carcinomas in Struma Ovarii and the Thyroid Gland With Different RAS Mutations (2018) (9)
- Thyroseq V3 Molecular Profiling for Tailoring the Surgical Management of Hürthle Cell Neoplasms (2018) (9)
- Do Ultrasound Patterns and Clinical Parameters Inform the Probability of Thyroid Cancer Predicted by Molecular Testing in Nodules with Indeterminate Cytology? (2021) (9)
- Template for Reporting Results of Biomarker Testing of Specimens From Patients With Thyroid Carcinoma. (2017) (9)
- On target cell numbers in radiation-induced H4-RET mediated papillary thyroid cancer (2001) (9)
- Tyrosine kinase expression is increased in papillary thyroid carcinoma of children and young adults. (2000) (9)
- Regulation of p 27 Kip 1 Protein Levels Contributes to Mitogenic Effects of the RET / PTC Kinase in Thyroid Carcinoma Cells (2004) (8)
- Detection of SYT-SSX Rearrangements in Synovial Sarcomas by Real-Time One-Step RT-PCR (2005) (8)
- Schistosomiasis of the cervix. (2003) (8)
- Multiple focal nodular hyperplasia of the liver in a 21-year-old woman (2004) (8)
- Spatial Positioning of RET and H4 Following Radiation Exposure Leads to Tumor Development (2001) (8)
- Non-invasive follicular thyroid neoplasm with papillary-like nuclei: reducing overtreatment by reclassifying an indolent variant of papillary thyroid cancer (2016) (8)
- Amplification-Based Methods (2015) (7)
- The oncocytic variant of poorly differentiated thyroid carcinoma shows a specific immune-related gene expression profile. (2020) (7)
- MOLECULAR PROFILE AND CLINICAL OUTCOMES IN DIFFERENTIATED THYROID CANCER PATIENTS PRESENTING WITH BONE METASTASIS. (2019) (6)
- Molecular Profile of Locally Aggressive Well Differentiated Thyroid Cancers (2020) (6)
- Characterizing Molecular Variants and Clinical Utilization of Next-generation Sequencing in Advanced Breast Cancer (2017) (6)
- Profi ling of Multifocal Tumors Using Next-Generation Sequencing Identifi es Concordant Occurrence of BRAF V600E Mutations (2015) (5)
- Suitability of animal models for studying radiation-induced thyroid cancer in humans: evidence from nuclear architecture. (2011) (5)
- Impact of molecular testing on detecting mimics of oncocytic neoplasms in thyroid fine‐needle aspirates diagnosed as follicular neoplasm of Hürthle cell (oncocytic) type (2021) (5)
- Diagnostic Surgical Pathology and Molecular Genetics of the Thyroid (2011) (5)
- Characterization of activating mutations of the MEK1 gene in papillary thyroid carcinomas. (2019) (5)
- Comprar Diagnostic Pathology and Molecular Genetics of the Thyroid | Yuri E. Nikiforov | 9780781774598 | Lippincott Williams & Wilkins (2009) (4)
- Spontaneous occurrence of an inhibitor of protein kinase C localization in a thyroid cancer cell line: role in thyroid tumorigenesis. (2001) (4)
- Evaluation of the Molecular Landscape of Pediatric Thyroid Nodules and Use of a Multigene Genomic Classifier in Children (2022) (4)
- Pharmacodynamic Effect of Iopanoic Acid on Free T3 and T4 Levels in Amiodarone-induced Thyrotoxicosis (2008) (3)
- Chapter 2 – Molecular Anatomic Pathology: Principles, Techniques, and Application to Immunohistologic Diagnosis (2011) (3)
- Autonomously functioning thyroid nodules are not associated with BRAF mutations (2004) (3)
- Pathologic Features of Thyroid Tumors (1998) (3)
- Performance of a Multigene Genomic Classifier in Thyroid Nodules with Suspicious for Malignancy Cytology (2022) (3)
- Radiation-Induced Thyroid Cancer: Lessons from Chernobyl (2006) (3)
- Prevalence, Significance, and Biological Behavior of ret/PTC Associated Papillary Thyroid Carcinoma— Author’s Response 1 (1997) (3)
- Prognostic of recurrence and survival in poorly differentiated thyroid cancer. (2022) (2)
- Advances in Brief High Prevalence of BRAF Mutations in Thyroid Cancer : Genetic Evidence for Constitutive Activation of the RET / PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carcinoma 1 (2003) (2)
- Application of Molecular Tests in Indeterminate Thyroid FNA (2019) (2)
- Association of comprehensive thyroid cancer molecular profiling with tumor phenotype and cancer-specific outcomes. (2022) (2)
- Mutations in Thyroid Tumorigenesis (2007) (2)
- Utilization of Molecular Markers in the Diagnosis and Management of Thyroid Nodules (2018) (2)
- Polymerase Chain Reaction (2001) (2)
- Chapter 8 Mechanisms of radiation-induced carcinogenesis: The thyroid model (1998) (2)
- BRAF Mutations in Papillary Thyroid Carcinoma: Diagnostic Role, Prognostic Implications, and a Guide for Clinical Management (2010) (2)
- Molecular Genetics and Diagnostics of Thyroid Cancer (2019) (2)
- Incidental Diagnosis of Parathyroid Lesions by Preoperative Use of Next-Generation Molecular Testing (2018) (2)
- Significance of what is not sampled: Characteristics of thyroid nonmicrocarcinomas (>1.0 cm) that were not targeted (2015) (2)
- The molecular pathways induced by radiation and leading to thyroid carcinogenesis. (2004) (2)
- Clinicopathologic Characteristics of Thyroid Nodules Positive for PTEN Mutations on Preoperative Molecular Testing (2021) (2)
- Can TP53-mutant follicular adenoma be a precursor of anaplastic thyroid carcinoma? (2021) (2)
- OR21-02 Impact of Nodule Size on the Probability of Hurthle Cell Carcinoma and Other Cancers in Thyroid Nodules with Multiple Chromosomal Copy Number Alterations (2020) (2)
- Thyroid: Papillary Carcinoma with inv(7)(q21q34) (2008) (1)
- A Case of Papillary Thyroid Carcinoma and Kostmann Syndrome: A Genomic Theranostic Approach for Comprehensive Treatment (2019) (1)
- Clinicopathologic features of thyroid nodules with PTEN mutations on preoperative testing. (2022) (1)
- Clinicopathological features and outcomes of thyroid nodules with EIF1AX mutations. (2022) (1)
- Genetic Events in Radiation-Induced Thyroid Cancer (2002) (1)
- Response to Letter to the Editor regarding follow‐up for NIFTP (2019) (1)
- What's in a Name? A Cost-Effectiveness Analysis of the Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Nomenclature Revision. (2021) (1)
- SUN-284 DICER1 Mutations in Adolescent Girls: Clinicopathological Findings and Genetic Correlation (2019) (1)
- MON-570 Clinical Utility of ThyroSeq v3 Genomic Classifier Test in Detecting Gene Fusions in Thyroid Nodules (2019) (1)
- Clinicopathologic Characteristics and Post-Surgical Follow-Up of NIFTP in the Post-Nomenclature Revision Era. (2022) (1)
- Abstract 2544: Associations between RET/PTC rearrangements, BRAF and RAS mutations and radiation dose, age at exposure, and latency in post-Chernobyl thyroid cancer (2012) (1)
- Editorial : RET / PTC Rearrangement — A Link between Hashimoto ’ s Thyroiditis and Thyroid Cancer (2006) (0)
- Neoplasms of Thyroid: Poorly differentiated thyroid carcinoma (2017) (0)
- Next-generation sequencing in a cohort of metastatic breast cancer (MBC) patients. (2015) (0)
- Abstract 3599: Prevalance and spectrum of chromosomal rearrangements in post-Chernobyl thyroid cancer. (2013) (0)
- Molecular Testing in Thyroid Cancer (2017) (0)
- The genomic, evolutionary and functional landscapes of anaplastic thyroid carcinoma (2023) (0)
- Unraveling the significance of TSHR mutations in indeterminate thyroid cytology specimens. (2023) (0)
- Different types of RET/PTC rearrangements are associated with different biological behavior of papillary thyroid carcinoma (2000) (0)
- Prevalence of WWP1 Gene Mutations in Patients with Thyroid Nodules. (2020) (0)
- MON-LB79 Do Ultrasound Patterns and Clinical Parameters Modify the Probability of Thyroid Cancer Predicted by Molecular Testing in Thyroid Nodules With Indeterminate Cytology? (2020) (0)
- Positive PIK3CA (P.H1047R) Mutation in a Benign Thyroid Nodule of a Patient With Men-1 Syndrome (2018) (0)
- Abstracts (2009) (0)
- Molecular profiling of papillary thyroid carcinomas in healthcare workers exposed to low dose radiation at the workplace (2022) (0)
- Benign Call Rate of ThyroSeq v3 Molecular Test (2018) (0)
- A thyroid EIF1AX story: how clinical, cytologic, and molecular surveillance led to appropriate management. (2022) (0)
- A preoperative molecular nomogram predicts central compartment lymph node metastasis in patients with papillary thyroid cancer (2014) (0)
- Molecular Testing Predicts Incomplete Response to Initial Therapy in Differentiated Thyroid Carcinoma without Lateral Neck or Distant Metastasis at Presentation: Retrospective Cohort Study. (2023) (0)
- 953 Loss of Heterozygosity Portends Poor Survival of Patients with Resected Periampullary Cancer (2008) (0)
- Identifying metastatic renal cell carcinoma in thyroid fine needle aspirates by molecular testing. (2022) (0)
- Chapter 1 Gene rearrangements in thyroid cancer (2006) (0)
- 10:58: Adequacy of Surgeon-Performed, Office-Based US Thyroid FNA (2007) (0)
- Targeted Mutation Detection in Advanced Breast Cancer Using MammaSeq Identifies RET as a Potential Contributor to Breast Cancer Metastasis (2018) (0)
- Molecular Profiles of Non-Invasive, Minimally Invasive and Invasive Follicular Patterned Thyroid Neoplasms with Papillary Nuclear Features. (2023) (0)
- DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis (2020) (0)
- 11:24: Correlation of Thyroid Microcarcinoma and Metastasis (2007) (0)
- Molecular Profile of Locally Aggressive Well Differentiated Thyroid Cancers (2020) (0)
- Targeted mutation detection in breast cancer using MammaSeq™ (2019) (0)
- Thyroid cancer molecular genetics: new oncogenes offer potential therapeutic targets (2004) (0)
- Coyne C, Johnson JT, Stewart AF, Nikiforova MN. Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective (2011) (0)
- AKAP9 (A kinase (PRKA) anchor protein (yotiao) 9) (2008) (0)
- Detecting Subtle Parathyroid Lesions from Thyroid Fine Needle Aspiration Specimens Using ThyroSeq v2 Targeted Next Generation Sequencing Assay (2015) (0)
- Abstract 2125: A new method for assessing fidelity of DSB repair shows involvement of different DNA repair mechanisms at specific sites in human genome (2012) (0)
- Significance of What is Not Sampled: Characteristics of Incidental Thyroid “Non-Microcarcinomas” (>1cm) (2013) (0)
- Neoplasms of Thyroid: Follicular thyroid carcinoma (2017) (0)
- Clinical Utility of GlioSeq Next-Generation Sequencing Test in Pediatric and Young Adult Patients With Brain Tumors. (2019) (0)
- Molecular Profiling of 50,734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management. (2023) (0)
- Colloid Content in Thyroid Follicular Neoplasm/Suspicious for Follicular Neoplasm Cytology Specimens (2012) (0)
- In Reply. (2015) (0)
- Estimation of Risk of Malignancy for Indeterminate Thyroid Cytology Diagnoses from Molecular Profiles (2019) (0)
- Prevalence and Spectrum of DICER1Mutations in Adult-Onset Thyroid Nodules (2021) (0)
- Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells. (2022) (0)
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