Yusaku Nakabeppu
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Molecular Biology
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Biochemistry
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Biology
Yusaku Nakabeppu's Degrees
- PhD Biochemistry University of Tokyo
- Bachelors Chemistry University of Tokyo
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(Suggest an Edit or Addition)Yusaku Nakabeppu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA binding activities of three murine Jun proteins: Stimulation by Fos (1988) (726)
- Regulation and expression of the adaptive response to alkylating agents. (1988) (582)
- Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments (1994) (573)
- Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. (1989) (550)
- Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy (2006) (447)
- A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity (1991) (396)
- Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs. (1999) (395)
- Chronic Fos-Related Antigens: Stable Variants of ΔFosB Induced in Brain by Chronic Treatments (1997) (317)
- Constitutive expression of zif268 in neocortex is regulated by synaptic activity. (1991) (304)
- Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase (2001) (292)
- JSAP1, a Novel Jun N-Terminal Protein Kinase (JNK)-Binding Protein That Functions as a Scaffold Factor in the JNK Signaling Pathway (1999) (274)
- Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids (2006) (252)
- Oxidative damage in nucleic acids and Parkinson's disease (2007) (250)
- Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study (2013) (245)
- Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption. (2003) (226)
- Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs (2008) (204)
- Intracellular Localization of 8-Oxo-dGTPase in Human Cells, with Special Reference to the Role of the Enzyme in Mitochondria (*) (1995) (204)
- DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1 (2010) (193)
- Chronic Alterations in Dopaminergic Neurotransmission Produce a Persistent Elevation of ΔFosB‐like Protein(s) in both the Rodent and Primate Striatum (1996) (190)
- Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide. (2001) (188)
- The Oxidized Forms of dATP Are Substrates for the Human MutT Homologue, the hMTH1 Protein* (1999) (186)
- XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. (2005) (179)
- Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease (2009) (165)
- Increased 8‐oxo‐dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease (1999) (160)
- Cellular Levels of 8-Oxoguanine in either DNA or the Nucleotide Pool Play Pivotal Roles in Carcinogenesis and Survival of Cancer Cells (2014) (155)
- Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage. (2001) (151)
- A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. (1997) (151)
- Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. (1995) (146)
- The Oxidized Deoxynucleoside Triphosphate Pool Is a Significant Contributor to Genetic Instability in Mismatch Repair-Deficient Cells (2004) (142)
- Metabolic fate of oxidized guanine ribonucleotides in mammalian cells. (1999) (142)
- Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion. (1994) (134)
- MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis. (2007) (134)
- Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer (2003) (132)
- An Oxidized Purine Nucleoside Triphosphatase, MTH1, Suppresses Cell Death Caused by Oxidative Stress* (2003) (129)
- 8-oxoguanine causes spontaneous de novo germline mutations in mice (2014) (127)
- The dopamine D1 receptor is a critical mediator for cocaine‐induced gene expression (2002) (124)
- 8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis. (2005) (124)
- Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson’s disease and related neurodegenerative disorders (2005) (120)
- Molecular genetics and structural biology of human MutT homolog, MTH1. (2001) (119)
- APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (2007) (119)
- Three-Dimensional Structure of a DNA Repair Enzyme, 3-Methyladenine DNA Glycosylase II, from Escherichia coli (1996) (119)
- Stress response gene ATF3 is a target of c‐myc in serum‐induced cell proliferation (2005) (117)
- 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction (2012) (114)
- The basic region of Fos mediates specific DNA binding. (1989) (110)
- Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines. (2008) (107)
- 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair. (2012) (104)
- Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors. (2001) (103)
- Replication-Associated Repair of Adenine:8-Oxoguanine Mispairs by MYH (2002) (102)
- Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation (2017) (100)
- Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria (2000) (95)
- Physical association of pyrimidine dimer DNA glycosylase and apurinic/apyrimidinic DNA endonuclease essential for repair of ultraviolet-damaged DNA. (1981) (95)
- Significance of error‐avoiding mechanisms for oxidative DNA damage in carcinogenesis (2007) (94)
- Regulatory mechanisms for induction of synthesis of repair enzymes in response to alkylating agents: ada protein acts as a transcriptional regulator. (1986) (92)
- Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain (2017) (92)
- A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. (2006) (91)
- Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis (2002) (91)
- Mutator Phenotype of MUTYH-null Mouse Embryonic Stem Cells* (2003) (90)
- Purification and structure of the intact Ada regulatory protein of Escherichia coli K12, O6-methylguanine-DNA methyltransferase. (1985) (86)
- MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides. (2006) (83)
- Cyclic AMP-regulated synthesis of the tissue inhibitors of metalloproteinases suppresses the invasive potential of the human fibrosarcoma cell line HT1080. (1995) (79)
- Proliferative activation of quiescent Rat-1A cells by delta FosB (1993) (79)
- RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS. (2007) (79)
- Synaptic regulation of immediate-early genes in brain. (1990) (78)
- APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (2007) (78)
- Purification and characterization of normal and mutant forms of T4 endonuclease V. (1982) (77)
- Molecular cloning of AtMMH, an Arabidopsis thaliana ortholog of the Escherichia coli mutM gene, and analysis of functional domains of its product (1998) (75)
- Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain (2002) (74)
- Cloning and characterization of the alkA gene of Escherichia coli that encodes 3-methyladenine DNA glycosylase II. (1984) (74)
- Structure and expression of the alkA gene of Escherichia coli involved in adaptive response to alkylating agents. (1984) (71)
- DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis (2011) (70)
- Genomic response to growth factors. (1988) (69)
- Induction of c‐Fos‐like and FosB‐like immunoreactivity reveals forebrain neuronal populations involved differentially in pup‐mediated maternal behavior in juvenile and adult rats (2000) (69)
- A Molecular Basis for the Selective Recognition of 2-Hydroxy-dATP and 8-Oxo-dGTP by Human MTH1* (2002) (68)
- Selective increase in cellular Aβ42 is related to apoptosis but not necrosis (2000) (67)
- ReviewThe Defense Mechanisms in Mammalian Cells against Oxidative Damage in Nucleic Acids and their Involvement in the Suppression of Mutagenesis and Cell Death (2004) (65)
- 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions (2016) (65)
- Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. (2003) (64)
- Synaptic Regulation of Immediate Early Gene Expression in Primary Cultures of Cortical Neurons (1991) (64)
- Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons (2006) (64)
- Regulation of Expression of the Human MTH1 Gene Encoding 8-Oxo-dGTPase (1997) (64)
- CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection (2003) (64)
- Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein. (2005) (64)
- Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: from mitochondria to nuclei. (2004) (63)
- Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase. (2010) (63)
- NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals (2010) (62)
- Transfer of the E. coli O6-methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N′-nitro-N-nitrosoguanidine (1986) (62)
- Narrow-band UVB induces more carcinogenic skin tumors than broad-band UVB through the formation of cyclobutane pyrimidine dimer. (2007) (62)
- Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death. (2008) (60)
- Structure and expression of the alkB gene of Escherichia coli related to the repair of alkylated DNA. (1986) (59)
- A Role for Oxidized DNA Precursors in Huntington's Disease–Like Striatal Neurodegeneration (2008) (57)
- Characterization of human polymorphic DNA repair methyltransferase. (2000) (56)
- Targeted disruption of one allele of the Y‐box binding protein‐1 (YB‐1) gene in mouse embryonic stem cells and increased sensitivity to cisplatin and mitomycin C (2004) (56)
- Futile short-patch DNA base excision repair of adenine:8-oxoguanine mispair. (2004) (55)
- Differential expression of cytokeratin after orthotopic implantation of newly established human tongue cancer cell lines of defined metastatic ability. (2000) (55)
- FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression (1995) (54)
- MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?☆ (2017) (54)
- Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. (2016) (54)
- Adaptive response: induced synthesis of DNA repair enzymes by alkylating agents (1987) (53)
- Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis. (2014) (51)
- Expression of hMTH1 in the hippocampi of control and Alzheimer's disease (2001) (51)
- MTH1, an Oxidized Purine Nucleoside Triphosphatase, Suppresses the Accumulation of Oxidative Damage of Nucleic Acids in the Hippocampal Microglia during Kainate-Induced Excitotoxicity (2006) (51)
- Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease (2016) (51)
- Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson’s disease (2006) (50)
- Celecoxib and 2,5‐dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β‐catenin signaling pathway (2016) (50)
- Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice. (2004) (50)
- Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation (2014) (50)
- Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism. (1999) (50)
- Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method. (2009) (50)
- Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia (2014) (49)
- Biochemical and physicochemical characterization of normal and variant forms of human MTH1 protein with antimutagenic activity. (1997) (49)
- Structure of Human MTH1, a Nudix Family Hydrolase That Selectively Degrades Oxidized Purine Nucleoside Triphosphates* (2004) (48)
- Functional sites of the Ada regulatory protein of Escherichia coli. Analysis by amino acid substitutions. (1988) (47)
- Oral ‘hydrogen water' induces neuroprotective ghrelin secretion in mice (2013) (47)
- A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice. (2000) (45)
- Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts. (2004) (44)
- Expression and Prognostic Significance ofO6-Methylguanine-DNA Methyltransferase in Hepatocellular, Gastric, and Breast Cancers (2001) (44)
- NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest (2010) (44)
- Contrasting Effects of Chronic Clozapine, SeroquelTM (ICI 204,636) and Haloperidol Administration on ΔFosB‐like Immunoreactivity in the Rodent Forebrain (1996) (44)
- Adenine DNA Glycosylase Activity of 14 Human MutY Homolog (MUTYH) Variant Proteins Found in Patients with Colorectal Polyposis and Cancer (2010) (43)
- MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. (2004) (42)
- ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells. (2010) (42)
- Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes. (2009) (42)
- Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis. (2006) (41)
- Therapeutic Approach to Neurodegenerative Diseases by Medical Gases: Focusing on Redox Signaling and Related Antioxidant Enzymes (2012) (41)
- Increased expression of versican in the inflammatory response to UVB- and reactive oxygen species-induced skin tumorigenesis. (2011) (40)
- Sensitivity of Escherichia coli (MutT) and human (MTH1) 8-oxo-dGTPases to in vitro inhibition by the carcinogenic metals, nickel(II), copper(II), cobalt(II) and cadmium(II). (1997) (40)
- Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis (2008) (38)
- GDNF promotes neurite outgrowth and upregulates galectin-1 through the RET/PI3K signaling in cultured adult rat dorsal root ganglion neurons (2013) (38)
- Expression of the ada gene of Escherichia coli in response to alkylating agents. Identification of transcriptional regulatory elements. (1988) (37)
- Functional Significance of the Conserved Residues for the 23-Residue Module among MTH1 and MutT Family Proteins* (1999) (37)
- A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae. (2004) (36)
- Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice. (2015) (36)
- Polymorphism in the human O6-methylguanine-DNA methyltransferase gene detected by PCR-SSCP analysis. (1996) (36)
- Contribution of Estrogen Receptor α to Oncogenic K-Ras-mediated NIH3T3 Cell Transformation and Its Implication for Escape from Senescence by Modulating the p53 Pathway* (2002) (36)
- Isoforms of JSAP1 scaffold protein generated through alternative splicing. (2000) (36)
- Intracellular localization and function of DNA repair methyltransferase in human cells. (1994) (35)
- Purification and structure of 3-methyladenine-DNA glycosylase I of Escherichia coli. (1986) (34)
- Altered expression of MUTYH and an increase in 8‐hydroxydeoxyguanosine are early events in ulcerative colitis‐associated carcinogenesis (2009) (34)
- Cloning and sequence of the gene encoding the major structural component of mannose-resistant fimbriae of Serratia marcescens (1988) (34)
- FosB Is Essential for the Enhancement of Stress Tolerance and Antagonizes Locomotor Sensitization by ΔFosB (2011) (34)
- A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA (2005) (32)
- fosB-Null Mice Display Impaired Adult Hippocampal Neurogenesis and Spontaneous Epilepsy with Depressive Behavior (2013) (32)
- Biological Significance of the Defense Mechanisms against Oxidative Damage in Nucleic Acids Caused by Reactive Oxygen Species: From Mitochondria to Nuclei (2004) (32)
- In Vitro Development of Mouse Embryonic Stem Cells Lacking JNK/Stress-activated Protein Kinase-associated Protein 1 (JSAP1) Scaffold Protein Revealed Its Requirement during Early Embryonic Neurogenesis* (2003) (32)
- Characterization of the genomic structure and expression of the mouse Apex2 gene. (2003) (32)
- Regulation of expression of the cloned ada gene in Escherichia coli. (1985) (32)
- Deficient Expression of O 6-Methylguanine-DNA Methyltransferase Combined With Mismatch-Repair Proteins hMLH 1 and hMSH 2 Is Related to Poor Prognosis in Human Biliary Tract Carcinoma (31)
- The conjunctive stimuli that cause long-term desensitization also predominantly induce c-Fos and Jun-B in cerebellar Purkinje cells. (1993) (31)
- Chronic atypical antipsychotics, but not haloperidol, increase neurogenesis in the hippocampus of adult mouse (2017) (30)
- Ability of various alkylating agents to induce adaptive and SOS responses: a study with lacZ fusion. (1985) (30)
- Artificial control of nuclear translocation of DNA repair methyltransferase. (1994) (30)
- Prognostic impact of MutT homolog‐1 expression on esophageal squamous cell carcinoma (2016) (30)
- MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration. (2012) (30)
- Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein. (2000) (30)
- Association of adipocyte enhancer‐binding protein 1 with Alzheimer's disease pathology in human hippocampi (2018) (29)
- Expression of adipose differentiation-related protein (ADRP) is conjointly regulated by PU.1 and AP-1 in macrophages. (2005) (29)
- D1-Receptor-related priming is attenuated by antisense-meditated 'knockdown' of fosB expression. (1998) (29)
- Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs. (2004) (28)
- Ischemia-induced CA1 neuronal death is preceded by elevated FosB and Jun expression and reduced NGFI-A and JunB levels. (1998) (28)
- Mice Heterozygous for the Xanthine Oxidoreductase Gene Facilitate Lipid Accumulation in Adipocytes (2014) (28)
- DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3β and expressions of cyclin D1 and TCF7L2 in cancer model mice. (2014) (27)
- Apurinic/Apyrimidinic Endonuclease 2 Is Necessary for Normal B Cell Development and Recovery of Lymphoid Progenitors after Chemotherapeutic Challenge (2011) (27)
- DNA-repair methyltransferase as a molecular device for preventing mutation and cancer (2005) (27)
- Clozapine‐, but not haloperidol‐, induced increases in ΔFosB‐like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors (2004) (26)
- Structure and function of dnaQ and mutD mutators of Escherichia coli. (1986) (25)
- Activation of Ada protein as a transcriptional regulator by direct alkylation with methylating agents. (1988) (25)
- Expression of the truncated E. coli O6-methylguanine methyltransferase gene in repair-deficient human cells and restoration of cellular resistance to alkylating agents. (1987) (25)
- Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. (2016) (25)
- MUTYH promotes oxidative microglial activation and inherited retinal degeneration. (2016) (25)
- 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle (2017) (25)
- Deficient expression ofO6-Methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma (2002) (25)
- Nucleotides function as endogenous chemical sensors for oxidative stress signaling (2010) (24)
- Defense mechanism to oxidative DNA damage in glial cells (2004) (24)
- The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice. (2006) (24)
- A comparative immunohistochemistry of O6‐methylguanine–DNA methyltransferase and p53 in diffusely infiltrating astrocytomas (2003) (24)
- fosB-Null Mice Display Impaired Adult Hippocampal Neurogenesis and Spontaneous Epilepsy with Depressive Behavior (2013) (24)
- Identification and Biochemical Characterization of a Novel Transcription Elongation Factor, Elongin A3* (2002) (24)
- Significance of the conserved amino acid sequence for human MTH1 protein with antimutator activity. (1997) (24)
- Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension. (2007) (23)
- FosB in rat striatum: Normal regional distribution and enhanced expression after 6‐month haloperidol administration (2001) (23)
- Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity* (2016) (22)
- Stabilization of cyclin E and cdk2 mRNAs at G1/S transition in Rat-1A cells emerging from the G0 state. (1995) (22)
- Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome. (2005) (22)
- Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer. (1995) (22)
- Neonatal Ventral Hippocampal Lesions Produce an Elevation of ΔFosB-Like Protein(s) in the Rodent Neocortex (2006) (22)
- Expression and prognostic significance of O6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers. (2001) (22)
- Down‐regulation of MET in hippocampal neurons of Alzheimer's disease brains (2014) (22)
- Mammalian Elongin A Is Not Essential for Cell Viability but Is Required for Proper Cell Cycle Progression with Limited Alteration of Gene Expression* 210 (2003) (22)
- Oxidative Stress and Microglial Response in Retinitis Pigmentosa (2020) (21)
- Cancer-Related PRUNE2 Protein Is Associated with Nucleotides and Is Highly Expressed in Mature Nerve Tissues (2011) (21)
- Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice. (2008) (21)
- The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice (2018) (21)
- Role of c-jun in the inhibition of erythropoietin receptor-mediated apoptosis. (1996) (21)
- Skin tumours induced by narrowband UVB have higher frequency of p53 mutations than tumours induced by broadband UVB independent of Ogg1 genotype. (2012) (20)
- Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines. (2012) (20)
- Association of MTH1 expression with the tumor malignant potential and poor prognosis in patients with resected lung cancer. (2017) (20)
- Selective increase in cellular A beta 42 is related to apoptosis but not necrosis. (2000) (20)
- Mutagenic target for hydroxyl radicals generated in Escherichia coli mutant deficient in Mn- and Fe- superoxide dismutases and Fur, a repressor for iron-uptake systems. (2002) (19)
- A variant form of hMTH1, a human homologue of the E coli mutT gene, correlates with somatic mutation in the p53 tumour suppressor gene in gastric cancer patients (2004) (19)
- Mouse RS21‐C6 is a mammalian 2′‐deoxycytidine 5′‐triphosphate pyrophosphohydrolase that prefers 5‐iodocytosine (2009) (19)
- Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria. (2000) (19)
- APE 1-and APE 2-dependent DNA breaks in immunoglobulin class switch recombination (18)
- Cloning and expression of the Bacillus subtilis methyltransferase gene in Escherichia coli ada- cells. (1989) (18)
- Regulation of the Neuronal Fate by ΔFosB and its Downstream Target, Galectin-1 (2005) (18)
- FosB gene products trigger cell proliferation and morphological alteration with an increased expression of a novel processed form of galectin-1 in the rat 3Y1 embryo cell line. (2002) (18)
- Antagonistic regulation of cell-matrix adhesion by FosB and DeltaFosB/Delta2DeltaFosB encoded by alternatively spliced forms of fosB transcripts. (2008) (17)
- Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformant. (2005) (17)
- Galectin‐1 deficiency improves axonal swelling of motor neurones in SOD1G93A transgenic mice (2015) (17)
- Abnormality in Wnt Signaling is Causatively Associated with Oxidative Stress-Induced Intestinal Tumorigenesis in MUTYH-Null Mice (2014) (17)
- Complexity of Stomach–Brain Interaction Induced by Molecular Hydrogen in Parkinson’s Disease Model Mice (2017) (16)
- Serum galectin-3, but not galectin-1, levels are elevated in schizophrenia: implications for the role of inflammation (2017) (16)
- OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model (2020) (16)
- Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo. (2015) (16)
- Proteolytic cleavage of Ada protein that carries methyltransferase and transcriptional regulator activities. (1988) (16)
- Molecular Pathophysiology of Insulin Depletion, Mitochondrial Dysfunction, and Oxidative Stress in Alzheimer's Disease Brain. (2019) (15)
- Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice (2016) (14)
- 8‐Chloro‐dGTP, a hypochlorous acid‐modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog (2002) (14)
- Apurinic/Apyrimidinic Endonuclease 2 Regulates the Expansion of Germinal Centers by Protecting against Activation-Induced Cytidine Deaminase–Independent DNA Damage in B Cells (2014) (14)
- A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain (2018) (14)
- Transfer of the E. coli O6-methylguanine methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N'-nitro-N-nitrosoguanidine. (1986) (14)
- MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease (2021) (14)
- PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions (2020) (13)
- Impairment of cardiomyogenesis in embryonic stem cells lacking scaffold protein JSAP1. (2005) (13)
- Fenton reaction‐induced renal carcinogenesis in Mutyh‐deficient mice exhibits less chromosomal aberrations than the rat model (2017) (13)
- Prevention of the Mutagenecity and Cytotoxicity of Oxidized Purine Nucleotides (2007) (13)
- MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis (2021) (13)
- Therapeutic Effects of Hydrogen in Animal Models of Parkinson's Disease (2011) (13)
- The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal (2006) (12)
- Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells (2016) (12)
- Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage. (2014) (12)
- Accumulation of Adenine DNA Glycosylase-sensitive Sites in Human Mitochondrial DNA* (2000) (12)
- Enhancement of Laminar FosB Expression in Frontal Cortex of Rats Receiving Long Chronic Clozapine Administration (2001) (12)
- Origins of Brain Insulin and Its Function. (2019) (11)
- Oxidative stress induces different tissue dependent effects on Mutyh-deficient mice. (2019) (11)
- A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App NL−F/NL−F knock‐in mouse model (2021) (10)
- Intracellular distribution of the antimutagenic enzyme MTH1 in the liver, kidney and testis of F344 rats and its modulation by cadmium. (2001) (10)
- 8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes (2019) (10)
- Immediate-early gene expression in the brain of the thiamine-deficient rat (2007) (10)
- Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes. (2017) (10)
- A unique structural feature of rabbit DNA repair methyltransferase as revealed by cDNA cloning. (1994) (10)
- Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer (2021) (9)
- Crystallization and preliminary X-ray diffraction studies of 3-methyladenine-DNA glycosylase II from Escherichia coli. (1988) (9)
- Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus. (2008) (9)
- Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein. (2006) (9)
- Role of tryptophan residues in the recognition of mutagenic oxidized nucleotides by human antimutator MTH1 protein. (2002) (9)
- A comprehensive screening system for damaged nucleotide-binding proteins. (2010) (9)
- A Role for SNX1 in the Regulation of EGF-Dependent Phosphorylated EGFR Endocytosis Via the Early/Late Endocytic Pathway in a Gefitinib-Sensitive Human Lung Cancer Cells (2011) (9)
- Regulation of the neuronal fate by DeltaFosB and its downstream target, galectin-1. (2005) (9)
- Structure and function ofdnaQ andmutD mutators ofEscherichia coli (1986) (9)
- Characterization of galectin-1-positive cells in the mouse hippocampus (2014) (9)
- Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury (2020) (8)
- Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1–/– mice (2020) (8)
- Changes in expression of delta FosB and the Fos family proteins following NMDA receptor activation in the rat striatum. (1997) (8)
- Neuroendocrine phenotypes in a boy with 5q14 deletion syndrome implicate the regulatory roles of myocyte-specific enhancer factor 2C in the postnatal hypothalamus. (2013) (7)
- Knockout-associated Lung Tumorigenesis and Its Suppression by Mth 1 Gene Disruption 1 (2003) (7)
- Angiotensin I-converting enzyme gene polymorphism modifies the smoking–cancer association: the Hisayama Study (2006) (7)
- DNA Replication and Transcription (2006) (7)
- Neurodegeneration caused by accumulation of an oxidized base lesion, 8-oxoguanine, in nuclear and mitochondrial DNA: from animal models to human diseases. (2017) (6)
- MUTYH prevents OGG 1 or APEX 1 from inappropriately processing its substrate or reaction product with its C-terminal domain (2004) (6)
- Expression of CRYM in different rat organs during development and its decreased expression in degenerating pyramidal tracts in amyotrophic lateral sclerosis (2018) (6)
- GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons (2020) (6)
- Erratum: MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death (Oncogenesis (2015) 4 (e121) DOI:doi:10.1038/oncsis.2014.35) (2015) (6)
- Purification and Characterization of Normal and Mutant Forms of T 4 Endonuclease V * (2001) (5)
- APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity in Pancreatic Cancer Cells (2021) (5)
- Mechanisms protecting genomic integrity from damage caused by reactive oxygen species: Implications for carcinogenesis and neurodegeneration (第12回公開シンポジウム「活性酸素の分子病態学」) (2001) (5)
- Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis. (2017) (5)
- Detection of angiotensin-converting enzyme gene insertion/deletion polymorphism from paraffin-embedded tissues: the Hisayama study. (2002) (5)
- Crystallization and preliminary X-ray analysis of human MTH1 complexed with two oxidized nucleotides, 8-oxo-dGMP and 2-oxo-dATP. (2006) (5)
- Erratum: Human Oggl, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide (Cancer Research (September 1, 2001) (6388-6393)) (2001) (5)
- An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV‐induced hepatocellular carcinoma (2018) (5)
- Action of T4 endonuclease V on polydeoxyribonucleotides with apyrimidinic or apurinic sites. (1982) (5)
- Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage. (2009) (4)
- Presence of potential nickel-responsive element(s) in the mouse MTH1 promoter. (2001) (4)
- Silencing of SNX 1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines (2012) (4)
- PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E‐deficient mice (2016) (4)
- Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus. (2013) (3)
- Mth1 deficiency provides longer survival upon intraperitoneal crocidolite injection in female mice (2020) (3)
- Molecular mechanism of adaptive response to alkylating agents. (1986) (3)
- The genes involved in the repair of alkylated DNA in Escherichia coli K-12 (1983) (3)
- Erratum: FosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior (Neuropsychopharmacology (2013) 38 (1374-1375) DOI: 10.1038/npp.2013.56) (2013) (3)
- Transcriptome Analysis in Hippocampus of Rats Prenatally Exposed to Valproic Acid and Effects of Intranasal Treatment of Oxytocin (2022) (3)
- Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation (2017) (3)
- Oxidative stress-induced tumorigenesis in the small intestines of DNA repair-deficient mice. (2011) (3)
- Neural stem cell–specific ITPA deficiency causes neural depolarization and epilepsy (2020) (3)
- PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions. (2020) (3)
- Requirement for two conserved cysteine residues in the Ada protein ofEscherichia coli for transactivation of theada promoter (1996) (2)
- MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model (2020) (2)
- Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions (2016) (2)
- Serum Anti-oligodendrocyte Autoantibodies in Patients With Multiple Sclerosis Detected by a Tissue-Based Immunofluorescence Assay (2021) (2)
- Nature of nontargeted radiation effects observed during fractionated irradiation-induced thymic lymphomagenesis in mice (2013) (2)
- Erratum: Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice (Scientific Reports (2016) 6 (22991) DOI: 10.1038/srep22991) (2016) (2)
- Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration (2016) (2)
- MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model (2021) (2)
- [MTH1, an oxidized purine nucleoside triphosphatase suppresses mitochondrial dysfunction and cell death caused by oxidative stress]. (2005) (2)
- A variant form of hMTH 1 , a human homologue of the E coli mutT gene , correlates with somatic mutation in the p 53 tumour suppressor gene in gastric cancer patients (2004) (2)
- Mutyh deficiency downregulates mitochondrial fusion proteins and causes cardiac dysfunction via α-ketoglutaric acid reduction with oxidative stress (2022) (2)
- Transcription Factors Induced by Growth-Stimulating Agents (1991) (2)
- REGlTLATION AND EXPRESSION OF THE i\DAPTIVE RESPONSE TO (1988) (2)
- 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Exacerbates Doxorubicin-Induced Cardiac Dysfunction (2022) (1)
- 2-Oxoadenosine induces cytotoxicity through intracellular accumulation of 2-oxo-ATP and depletion of ATP but not via the p38 MAPK pathway (2017) (1)
- [Biological significance of base damage and its repair in brain and neurons]. (2001) (1)
- Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation (2021) (1)
- 2115 The conjunctive stimuli that cause long-term desensitization also predominantly induce c-fos/jun-b in cerebellar purkinje cells (1993) (1)
- [Regulation of cyclin E and Cdk2 expression at G1/S transition: post-transcriptional reguration mediated by delta FosB]. (1996) (1)
- Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome (2015) (1)
- Shank3a/b isoforms regulate the susceptibility to seizures and thalamocortical development in the early postnatal period of mice (2023) (0)
- Neural stem cell specific ITPA deficiency causes depolarization of neurons, resulting in epileptic seizure and early death in mice (2019) (0)
- Mutagenesis induced by X-irradiation and its avoidance mechanism (2004) (0)
- Influence of ITPA-deficiency on mammalian cells and mouse central nerve system (2016) (0)
- 2-Oxoadenosine induces cytotoxicity through intracellular accumulation of 2-oxo-ATP and depletion of ATP but not via the p38 MAPK pathway (2017) (0)
- The oxidative DNA damage and germline mutation (2009) (0)
- Defective Base Excision Repair Associated with MUTYH (2018) (0)
- Isolation and Identification of E. coli MutT Homologues in Saccharomyces cerevisiae (2002) (0)
- Mutator Mutation in Carcinogenesis. (1996) (0)
- Positive regulation of adaptive response by direct methylation of Ada protein (1988) (0)
- pH-dependent substrate recognition in human MTH1 (2011) (0)
- fosB-null mice exhibit impaired adult hippocampal neurogenesis and spontaneous epileptic seizures (2010) (0)
- Poor proliferation of neural progenitors in the dentate gyrus of hippocampus in adult fosB-null mice exhibiting increased susceptibility for spontaneous epileptic seizures (2009) (0)
- Tokuda Akihiro Tomida Shinya Toyokuni Hitoshi Tsuda Shoichiro Tsugane Tatsuhiko Tsunoda Heiichiro Udono Koji Ueda Yoshimasa Uehara Hiroo Ueno Kazuo Umezawa Toshikazu Ushijima Toshihiko Wakabayashi Kenji Wakai Tetsuro Watabe (2016) (0)
- Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor , Elongin A Running title : Targeted disruption of Elongin A gene in mice (0)
- Deficiency of MTH1 and/or OGG1 increases the accumulation of 8-oxoguanine in the brain of the App NL-G-F/NL-G-F knock-in mouse model of Alzheimer’s disease, accompanied by accelerated microgliosis and reduced anxiety-like behavior (2021) (0)
- Comprehensive analysis of gene expression profiles regulated by fosB gene in brain (2011) (0)
- Cloning andSequence oftheGeneEncoding theMajorStructural Component ofMannose-Resistant Fimbriae ofSerratia marcescens (1988) (0)
- Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II) (2021) (0)
- AO-01-1 A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse ○ (2018) (0)
- Region specific expression of the defense enzymes MTH1, OGG1 and MUTYH against oxidative damage in nucleic acids in the substantia nigra of mouse (2011) (0)
- Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP (2017) (0)
- Proliferative Activation ofQuiescent Rat-lACells byAFosB (1993) (0)
- High-resolution X-ray diffraction study of the hMTH1 mutant (2008) (0)
- 2P013 Crystal structure of hMTH1-8-oxo-dGTP complex and its active site (2005) (0)
- O3-13-02 CHRONIC TREATMENT WITH A CNTF-DERIVED PEPTIDE REVERSES DENDRITIC AND SYNAPTIC PLASTICITY DEFICITS, COGNITIVE IMPAIRMENTAND TAU PATHOLOGY IN AN ALZHEIMER’S DISEASE MOUSE MODEL (2013) (0)
- 3P022 Crystal structure of 8-oxo-dATP-hMTH1 complex reveals a diversity of substrate recognition by hMTH1(Proteins-structure and structure-function relationship,Poster Presentations) (2007) (0)
- [Impact of damaged genes: effects on replication and transcription]. (1999) (0)
- A study of de novo germline mutation due to oxidative DNA damage (II) (2013) (0)
- Spontaneous tumorigenesis in mice with a targeted disruption of the MYH gene. (2002) (0)
- T-type calcium channel enhancer SAK3 improves cognition and inhibits amyloid beta accumulation in AppNL-F knock-in mice (2018) (0)
- Mitochondrial MUTYH-dependent striatal degeneration (2010) (0)
- Solution structure of the hMTH1, a nucleotide pool sanitization enzyme (2003) (0)
- The 4th International Symposium on 3R; DNA replication, recombination and repair. (2004) (0)
- ＜Symposium III＞Oxidative damage in brain genome and neuroprotection (2010) (0)
- Complexity of Stomach–Brain Interaction Induced by Molecular Hydrogen in Parkinson’s Disease Model Mice (2017) (0)
- Structure and function of the DNA repair enzyme 3-methyladenine DNA glycosylase II (1996) (0)
- Results Reduction in XOR Gene Expression Facilitates an Increase in Body Weight With Aging (0)
- Corrigendum to “MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease” (2023) (0)
- Crystal structure of hMTH1 in complex with its reaction product, 8-oxo-dGMP (2005) (0)
- Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition. (2023) (0)
- Correction: PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions (2021) (0)
- A new and rapid sensitive luciferase-based method for evaluating the activity of ITPase enzyme (2008) (0)
- Defense Mechanisms against Oxidative Damages of Nucleic Acids in Mitochondria : Implication in Neural Cell Death (1998) (0)
- Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1-/- mice (2021) (0)
- Substrate recognition by the human MTH1 protein. (2002) (0)
- Oxidative damage in nucleic acids in Huntington's disease model (2007) (0)
- Deficient expression of O6-methylguanine-DNA methyltransferase correlates with the prognosis of hepatocellular carcinoma (2000) (0)
- Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA (2021) (0)
- in APEX2-null mice Growth retardation and dyslymphopoiesis accompanied by G2/M arrest (2013) (0)
- Galectin-1 promotes neurogenesis in the dentate gyrus of mouse hippocampus after brain damage caused by excitotoxicity (2007) (0)
- APE2 Promotes AID-Dependent Somatic Hypermutation in Primary B Cell Cultures That Is Suppressed by APE1. (2023) (0)
- Mitochondrial toxin, 3-nitropropionic acid induces MUTYH-dependent striatal degeneration (2009) (0)
- Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 6.5 (2018) (0)
- Chemotherapeutic Challenge and Recovery of Lymphoid Progenitors after Necessary for Normal B Cell Development Apurinic/Apyrimidinic Endonuclease 2 Is (2011) (0)
- DNA repair byproduct 8-oxoguanine base promotes myoblast differentiation (2023) (0)
- Molecular mechanisms of repair of dna damaged by radiation (1981) (0)
- Identification of a new transfer rna gene in escherichia coli (1985) (0)
- Diabetes Mellitus, A risk factor for Alzheimer's Disease (2019) (0)
- Oxidative DNA Damage in Microglia Exacerbates Retinal Inflammation and Degeneration through MUTYH-mediated Base Excision Repair in a Mouse Model of Retinitis Pigmentosa (2016) (0)
- ΔFosB and/or Δ2ΔFosB regulate proliferation of adult hippocampal neural progenitor cells and suppress spontaneous epileptic seizures (2011) (0)
- [Defense mechanisms against oxidative damage in mitochondrial genome]. (2005) (0)
- Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer's disease model mice (2013) (0)
- P-9-3 Similar effects of chronic clozapine and ‘Seroquel’ (ICI 204,636) administration on 1FosB expression in the forebrain (1996) (0)
- Ionizing radiation-induced mutagenesis in Ogg1 knockout mice (2005) (0)
- Developmental profiles of CRYM in rat newborn brains and its decreased expression in pyramidal tract degeneration of amyotrophic lateral sclerosis (2017) (0)
- Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP (2017) (0)
- Analysis of gene expression regulation in mouse brain by FOSB isoforms (2016) (0)
- Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0 (2017) (0)
- Co-regulation of Cxcl1 and versican in inflammatory response in UVB induced reactive oxygen species in the skin (2017) (0)
- Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP (2017) (0)
- Oxidative stress boosts intestinal tumor incidence and a unique mutational signature in Mutyh deficient mice (2016) (0)
- Expression of human mitochondrial transcriptional factor A (hTFAM) improves cognitive function in Alzheimer?s disease model mice (2014) (0)
- Cloning and Characterization of the aZkA Gene of Escherichia coli That Encodes 3-Methyladenine DNA Glycosylase 11" (2001) (0)
- International Symposium on "Germline mutagenesis and biodiversification". (2014) (0)
- Serum galectin-3, but not galectin-1, levels are elevated in schizophrenia: implications for the role of inflammation (2017) (0)
- NMR studies of the human MTH1 enzyme, a nucleoside triphosphate pyrophosphohydrolase (1999) (0)
- Requirement for two conserved cysteine residues in the Ada protein of (1996) (0)
- Oxidative damage in brain genome and neuroprotection (2010) (0)
- Possible target gene abnormality in 06-methyl-guanine-DNA methyltransferase (MGMT) deficient phenotype in gall bladder carcinoma (2000) (0)
- Corrigendum: Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice (2016) (0)
- Role of 8-oxoguanine accumulated in nuclear or mitochondrial DNA in the development of Alzheimer’s disease (2016) (0)
- Damage in B Cells Independent DNA − ytidine Deaminase by Protecting against Activation-Induced C Regulates the Expansion of Germinal Centers Apurinic / Apyrimidinic Endonuclease 2 (2014) (0)
- ΔFosB promotes neurogenesis in the dentate gyrus of mouse hippocampus after brain damage caused by excitotoxicity (2007) (0)
- Impaired hippocampal neurogenesis in App-knock-in model mice of Alzheimer’s disease (2016) (0)
- Quantitative detection of oxidative DNA damage in brains of the triple transgenic Alzheimer's disease mouse model (2013) (0)
- Erratum: Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome (DNA Research (2015) 12:1 (39-51) DOI: 10.1093/dnares/12.1.39) (2015) (0)
- What have we learned from cultured adult dorsal root ganglion neurons (2014) (0)
- [Cell growth regulation and early response genes]. (1994) (0)
- Mutator mouse as a spontaneous genetic disease model animal (2017) (0)
- MUTYH, a Base Excision Repair Enzyme against Oxidative DNA Damage, Induces Single-strand Break Formation and Mediates Photoreceptor Cell Death in a Mouse Model of Retinitis Pigmentosa (2015) (0)
- 191 Mutagenesis induced by X-irradiation in Mth1 knockout mice(Mutation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society) (2003) (0)
- Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I) (2021) (0)
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What Schools Are Affiliated With Yusaku Nakabeppu?
Yusaku Nakabeppu is affiliated with the following schools:
