Yvan Vander Heyden

Yvan Vander Heyden's AcademicInfluence.com Rankings

Yvan Vander Heyden

Chemistry

#3357

World Rank

#4372

Historical Rank

Analytical Chemistry

#126

World Rank

#133

Historical Rank

chemistry Degrees

Download Badge

Chemistry

Why Is Yvan Vander Heyden Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Yvan Vander Heyden's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidance for robustness/ruggedness tests in method validation. (2001) (525)
Near-infrared spectroscopy applications in pharmaceutical analysis. (2007) (377)
Robust statistics in data analysis — A review: Basic concepts (2007) (320)
Chromatographic separation techniques and data handling methods for herbal fingerprints: a review. (2011) (277)
Experimental designs and their recent advances in set-up, data interpretation, and analytical applications. (2011) (265)
Ruggedness and robustness testing. (2007) (187)
Assessment of new constraints applied to the alternating least squares method (1997) (185)
HILIC methods in pharmaceutical analysis. (2010) (165)
A comparison of three algorithms for chromatograms alignment. (2006) (163)
Screening approach for chiral separation of pharmaceuticals. Part III. Supercritical fluid chromatography for analysis and purification in drug discovery. (2005) (158)
Supercritical fluid chromatography for the enantioseparation of pharmaceuticals. (2012) (153)
Raman spectroscopy as a process analytical technology (PAT) tool for the in-line monitoring and understanding of a powder blending process. (2008) (140)
Reappraisal of hypothesis testing for method validation : detection of systematic error by comparing the means of two methods or of two laboratories (1995) (139)
Screening approach for chiral separation of pharmaceuticals (2002) (138)
Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells. (2006) (136)
The occurrence of N-nitrosamines, residual nitrite and biogenic amines in commercial dry fermented sausages and evaluation of their occasional relation. (2014) (132)
Similarity analyses of chromatographic herbal fingerprints: a review. (2013) (132)
Automatic program for peak detection and deconvolution of multi-overlapped chromatographic signals part I: peak detection. (2005) (129)
Method development for HILIC assays. (2008) (128)
Screening approach for chiral separation of pharmaceuticals part II. Reversed-phase liquid chromatography. (2002) (126)
The use of CART and multivariate regression trees for supervised and unsupervised feature selection (2005) (120)
A performance comparison of modern statistical techniques for molecular descriptor selection and retention prediction in chromatographic QSRR studies (2005) (118)
Implementation of a process analytical technology system in a freeze-drying process using Raman spectroscopy for in-line process monitoring. (2007) (116)
Classification of drugs in absorption classes using the classification and regression trees (CART) methodology. (2005) (112)
Recent advancements in detecting sugar-based adulterants in honey – A challenge (2017) (112)
A review on the application of chromatographic methods, coupled to chemometrics, for food authentication (2018) (112)
Review on modelling aspects in reversed-phase liquid chromatographic quantitative structure-retention relationships. (2007) (112)
Polyphenols isolated from antiradical extracts of Mallotus metcalfianus. (2009) (111)
Ruggedness tests on the high-performance liquid chromatography assay of the United States Pharmacopeia xxii for tetracycline hydrochloride - a comparison of experimental-designs and statistical interpretations (1995) (109)
Pretreatments of chromatographic fingerprints for quality control of herbal medicines. (2006) (108)
Influence of putrescine, cadaverine, spermidine or spermine on the formation of N-nitrosamine in heated cured pork meat. (2011) (107)
HPTLC methods to assay active ingredients in pharmaceutical formulations: a review of the method development and validation steps. (2012) (103)
Development, optimization and validation of a fingerprint of Ginkgo biloba extracts by high-performance liquid chromatography. (2005) (94)
Automatic program for peak detection and deconvolution of multi-overlapped chromatographic signals part II: peak model and deconvolution algorithms. (2005) (92)
Feature selection methods in QSAR studies. (2012) (91)
Prediction of total green tea antioxidant capacity from chromatograms by multivariate modeling. (2005) (89)
The effect of preprocessing methods in reducing interfering variability from near-infrared measurements of creams. (2004) (89)
Chiral separations in sub- and supercritical fluid chromatography. (2008) (89)
Prediction of peptide retention at different HPLC conditions from multiple linear regression models. (2005) (89)
Analytical techniques for metabolomic studies: a review. (2019) (88)
Multivariate adaptive regression splines (MARS) in chromatographic quantitative structure-retention relationship studies. (2004) (88)
Classification of Chinese honeys according to their floral origin by near infrared spectroscopy. (2012) (85)
Determination of system suitability limits with a robustness test (1999) (85)
Rapid screening for chiral separations by short‐end injection capillary electrophoresis using highly sulfated cyclodextrins as chiral selectors (2001) (80)
Screening approach for chiral separation of pharmaceuticals IV. Polar organic solvent chromatography. (2006) (80)
Classification and regression tree analysis for molecular descriptor selection and retention prediction in chromatographic quantitative structure-retention relationship studies. (2003) (79)
Exploration of linear multivariate calibration techniques to predict the total antioxidant capacity of green tea from chromatographic fingerprints. (2008) (78)
Gas-chromatographic fatty-acid fingerprints and partial least squares modeling as a basis for the simultaneous determination of edible oil mixtures. (2005) (78)
Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Evaluation of 36 test parameters: repeatability, reproducibility and correlation. (2002) (77)
Chiral separations in polar organic solvent chromatography: updating a screening strategy with new chlorine-containing polysaccharide-based selectors. (2008) (75)
Ruggedness tests for a high-performance liquid Chromatographic assay: Comparison of an evaluation at two and three levels by using two-level Plackett-Burman designs (1995) (72)
Benchmarking of QSAR Models for Blood-Brain Barrier Permeation (2007) (71)
Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Rational column classification by a minimal number of column test parameters. (2003) (70)
Definition and system implementation of strategies for method development of chiral separations in normal- or reversed-phase liquid chromatography using polysaccharide-based stationary phases. (2004) (67)
Minimal number of chromatographic test parameters for the characterisation of reversed-phase liquid chromatographic stationary phases. (2002) (67)
Development of a ginkgo biloba fingerprint chromatogram with UV and evaporative light scattering detection and optimization of the evaporative light scattering detector operating conditions. (2005) (67)
Determining orthogonal chromatographic systems prior to the development of methods to characterise impurities in drug substances. (2003) (65)
Enantioselective capillary electrochromatography: Recent developments and new trends (2011) (62)
Quantitative structure-retention and retention-activity relationships of beta-blocking agents by micellar liquid chromatography. (2001) (62)
Chiral separations of cathinone and amphetamine-derivatives: Comparative study between capillary electrochromatography, supercritical fluid chromatography and three liquid chromatographic modes. (2016) (62)
Electrophoretic separation strategy for chiral pharmaceuticals using highly-sulfated and neutral cyclodextrins based dual selector systems (2004) (61)
Robust Cross-Validation of Linear Regression QSAR Models (2008) (60)
Selection of reversed-phase liquid chromatographic columns with diverse selectivity towards the potential separation of impurities in drugs. (2004) (58)
Evaluation of dissolution profiles using principal component analysis. (2001) (58)
Classification Tree Models for the Prediction of Blood-Brain Barrier Passage of Drugs (2006) (58)
Exploratory chemometric analysis of the classification of pharmaceutical substances based on chromatographic data. (2000) (58)
Similarity analyses of chromatographic fingerprints as tools for identification and quality control of green tea. (2012) (57)
Chromatographic fingerprint development for herbal extracts: a screening and optimization methodology on monolithic columns. (2007) (57)
Enantioseparations of pharmaceuticals with capillary electrochromatography: A review. (2016) (56)
Characterisation of reversed-phase liquid-chromatographic columns by chromatographic tests comparing column classification based on chromatographic parameters and column performance for the separation of acetylsalicylic acid and related compounds. (2004) (56)
Sequential uniform designs for fingerprints development of Ginkgo biloba extracts by capillary electrophoresis. (2006) (55)
Determining orthogonal and similar chromatographic systems from the injection of mixtures in liquid chromatography-diode array detection and the interpretation of correlation coefficients color maps. (2004) (54)
Potential antioxidant compounds in Mallotus species fingerprints. Part I: Indication, using linear multivariate calibration techniques. (2009) (54)
Chemometric treatment of vanillin fingerprint chromatograms. Effect of different signal alignments on principal component analysis plots. (2006) (54)
Robust partial least squares model for prediction of green tea antioxidant capacity from chromatograms. (2007) (54)
Development of HPLC fingerprints for Mallotus species extracts and evaluation of the peaks responsible for their antioxidant activity. (2009) (54)
Characterization and classification of stationary phases in HPLC and SFC – a review. (2015) (53)
Fast separations on monolithic silica columns: method transfer, robustness and column ageing for some case studies. (2003) (53)
Advanced QSRR modeling of peptides behavior in RPLC. (2010) (52)
Towards better understanding of feature-selection or reduction techniques for Quantitative Structure–Activity Relationship models (2013) (52)
Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography. (2012) (52)
Lawsone accumulation in normal and transformed cultures of henna, Lawsonia inermis (1997) (52)
Chiral separations in normal phase liquid chromatography: enantioselectivity of recently commercialized polysaccharide-based selectors. Part I: enantioselectivity under generic screening conditions. (2011) (51)
Robustness testing of a reversed-phase high-performance liquid chromatographic assay: comparison of fractional and asymmetrical factorial designs. (2000) (51)
Recent developments in chromatographic fingerprints from herbal products: set-up and data analysis. (2010) (50)
Future of high pressure liquid chromatography: do we need porosity or do we need pressure? (2006) (50)
QSRR modeling for diverse drugs using different feature selection methods coupled with linear and nonlinear regressions. (2012) (50)
Enantioselectivity of polysaccharide-based chiral stationary phases in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases. (2012) (48)
Orthogonality and similarity within silica-based reversed-phased chromatographic systems. (2005) (48)
The use of experimental design in separation science (2009) (48)
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. (2007) (48)
Recent advances in untargeted and targeted approaches applied in herbal-extracts and essential-oils fingerprinting - A review. (2020) (48)
Evaluation of size-exclusion chromatography and size-exclusion electrochromatography calibration curves. (2002) (47)
Set-up and evaluation of interlaboratory studies. (2007) (47)
Rapid development of the enantiomeric separation of beta-blockers by capillary electrophoresis using an experimental design approach. (1999) (47)
Determination of the enantiomeric purity of dexfenfluramine by capillary electrophoresis: use of a Plackett—Burman design for the optimization of the separation (1996) (47)
Seasonal, gender and regional variations in total phenolic, flavonoid, and condensed tannins contents and in antioxidant properties from Pistacia atlantica ssp. leaves (2017) (46)
Chiral separation strategy in polar organic solvent chromatography and performance comparison with normal-phase liquid and supercritical-fluid chromatography. (2006) (46)
Mallotus species from Vietnamese mountainous areas: phytochemistry and pharmacological activities (2010) (46)
Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer (2018) (45)
Knowledge-based system for method development of chiral separations with capillary electrophoresis using highly-sulphated cyclodextrins. (2002) (45)
Chromatographic analysis of salicylic compounds in different species of the genus Salix. (2007) (44)
Validation of an HPLC method on short columns to assay ketoconazole and formaldehyde in shampoo. (2003) (44)
Retention prediction of peptides based on uninformative variable elimination by partial least squares. (2006) (44)
Antioxidant activity of Vitis vinifera, Punica granatum, Citrus aurantium and Opuntia ficus indica fruits cultivated in Algeria (2019) (43)
Ruggedness testing of chromatographic methods: selection of factors and levels. (1998) (43)
A separation strategy combining three HPLC modes and polysaccharide-based chiral stationary phases. (2013) (43)
Optimisation by experimental design of a capillary electrophoretic method for the separation of several inhibitors of angiotensin-converting enzyme using alkylsulphonates. (2002) (43)
Improved variable reduction in partial least squares modelling based on predictive-property-ranked variables and adaptation of partial least squares complexity. (2011) (43)
Near-infrared spectroscopy for in-line monitoring of protein unfolding and its interactions with lyoprotectants during freeze-drying. (2012) (43)
Three-level screening designs for the optimisation or the ruggedness testing of analytical procedures (1993) (43)
Estimating Uncertainty (42)
Exploration of linear modelling techniques and their combination with multivariate adaptive regression splines to predict gastro-intestinal absorption of drugs. (2007) (41)
Generic chiral method development in supercritical fluid chromatography and ultra-performance supercritical fluid chromatography. (2014) (41)
Exploratory analysis of chromatographic fingerprints to distinguish rhizoma Chuanxiong and rhizoma Ligustici. (2010) (40)
Automated alignment of one-dimensional chromatographic fingerprints. (2010) (40)
High Enantioselective Novozym 435-Catalyzed Esterification of (R,S)-Flurbiprofen Monitored with a Chiral Stationary Phase (2015) (40)
First inter‐laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities (2018) (40)
Validation of a fluorimetric assay for 4-aminophenol in paracetamol formulations. (2008) (40)
Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat. (2010) (40)
Development of a fluid bed granulation process control strategy based on real-time process and product measurements. (2012) (40)
Chemometric comparison of recent chromatographic and electrophoretic methods in a quantitative structure-retention and retention-activity relationship context. (2003) (40)
Robust SIMCA-bounding influence of outliers (2007) (39)
Pharmaceutical-enantiomers resolution using immobilized polysaccharide-based chiral stationary phases in supercritical fluid chromatography. (2014) (38)
Improved sensitivity of the nano ultra-high performance liquid chromatography-tandem mass spectrometric analysis of low-concentrated neuropeptides by reducing aspecific adsorption and optimizing the injection solvent. (2014) (38)
Robustness testing of chiral separations by capillary electrophoresis using highly-sulfated cyclodextrins. (2003) (38)
Antidiabetic, dermatoprotective, antioxidant and chemical functionalities in Zizyphus lotus leaves and fruits (2019) (38)
Exploration and classification of chromatographic fingerprints as additional tool for identification and quality control of several Artemisia species. (2014) (38)
Prediction of enantioselectivity using chirality codes and Classification and Regression Trees (2005) (38)
Xanthones and Cancer: from Natural Sources to Mechanisms of Action (2019) (38)
Classification and authentication of Iranian walnuts according to their geographical origin based on gas chromatographic fatty acid fingerprint analysis using pattern recognition methods (2017) (37)
Evaluation of chromatographic descriptors for the prediction of gastro-intestinal absorption of drugs. (2007) (37)
Characterization and classification of PGI Moroccan Argan oils based on their FTIR fingerprints and chemical composition (2017) (37)
Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases (2005) (36)
Randomization tests to identify significant effects in experimental designs for robustness testing (2006) (36)
A ruggedness test strategy for procedure related factors: experimental set-up and interpretation. (1998) (36)
Enantioseparations of basic and bifunctional pharmaceuticals by capillary electrochromatography using polysaccharide stationary phases (2003) (36)
Potential antioxidant compounds in Mallotus species fingerprints. Part II: fingerprint alignment, data analysis and peak identification. (2012) (36)
Optimization of a reversed-phase-high-performance thin-layer chromatography method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculosis tablets. (2012) (35)
Chapter 3 Review of the use of robustness and ruggedness in analytical chemistry (1996) (34)
Facilitated Column Ranking and Selection in Reversed-Phase Liquid Chromatographic Analysis (2004) (34)
Raman spectroscopy and multivariate analysis for the rapid discrimination between native-like and non-native states in freeze-dried protein formulations. (2013) (34)
Chiral separations in normal-phase liquid chromatography: Enantioselectivity of recently commercialized polysaccharide-based selectors. Part II. Optimization of enantioselectivity. (2011) (33)
Improving method capability of a drug substance HPLC assay. (2006) (33)
In silico predictions of ADME-Tox properties: drug absorption. (2011) (33)
Statistical Confidence for Variable Selection in QSAR Models via Monte Carlo Cross-Validation (2008) (33)
Chemometric analysis of soil pollution data using the Tucker N-way method (2006) (33)
Fast development of separation methods for the chiral analysis of amino acid derivatives using capillary electrophoresis and experimental designs. (2000) (33)
Microfluidics in macro-biomolecules analysis: macro inside in a nano world (2010) (32)
Quality control of Citri reticulatae pericarpium: exploratory analysis and discrimination. (2011) (32)
Prediction of gastro-intestinal absorption using multivariate adaptive regression splines. (2005) (32)
Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology (2016) (32)
Enlarging the bottleneck in the analysis of alkaloids: A review on sample preparation in herbal matrices (2016) (32)
Antioxidant activities of Pistacia atlantica extracts modeled as a function of chromatographic fingerprints in order to identify antioxidant markers (2016) (31)
Capillary electrochromatographic chiral separations with potential for pharmaceutical analysis. (2005) (31)
Qualitative and quantitative analysis of peanut adulteration in almond powder samples using multi-elemental fingerprinting combined with multivariate data analysis methods (2017) (31)
Chiral separations in reversed-phase liquid chromatography: evaluation of several polysaccharide-based chiral stationary phases for a separation strategy update. (2012) (31)
Batch-to-batch N-glycosylation study of infliximab, trastuzumab and bevacizumab, and stability study of bevacizumab (2016) (31)
Application of tetraoxadiaza-crown ether derivatives as chiral selector modifiers in capillary electrophoresis. (2004) (30)
Boosted regression trees, multivariate adaptive regression splines and their two-step combinations with multiple linear regression or partial least squares to predict blood-brain barrier passage: a case study. (2008) (30)
Enantioselectivity of polysaccharide-based chiral selectors in polar organic solvents chromatography: implementation of chlorinated selectors in a separation strategy. (2013) (30)
Method development for impurity profiling in SFC: The selection of a dissimilar set of stationary phases. (2015) (30)
Selected-ion flow-tube mass-spectrometry (SIFT-MS) fingerprinting versus chemical profiling for geographic traceability of Moroccan Argan oils. (2018) (30)
HPLC analysis of polyphenols in the fruits of Rubus idaeus L. (Rosaceae) (2010) (29)
Comparison of Plackett-Burman and supersaturated designs in robustness testing. (2007) (29)
Influence of particle size on the quantitative determination of salicylic acid in a pharmaceutical ointment using FT-Raman spectroscopy. (2007) (29)
Development and validation of a normal-phase HPTLC method for the simultaneous analysis of lamivudine, stavudine and nevirapine in fixed-dose combination tablets. (2011) (29)
Fast generic chiral separation strategies using electrophoretic and liquid chromatographic techniques. (2008) (28)
Updating a generic screening approach in sub- or supercritical fluid chromatography for the enantioresolution of pharmaceuticals (2013) (28)
Increasing conclusiveness of metabonomic studies by chem-informatic preprocessing of capillary electrophoretic data on urinary nucleoside profiles. (2007) (28)
Evaluation of different warping methods for the analysis of CE profiles of urinary nucleosides (2007) (28)
Cyclodextrin-based ultrasonic-assisted microwave extraction and HPLC-PDA-ESI-ITMSn separation and identification of hydrophilic and hydrophobic components of Polygonum cuspidatum: A green, rapid and effective process (2016) (28)
Evaluation of chemometric techniques to select orthogonal chromatographic systems. (2006) (28)
Selection of orthogonal chromatographic systems based on parametric and non-parametric statistical tests (2005) (28)
Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology. (2020) (28)
Comparison of several criteria to decide on the significance of effects in a robustness test with an asymmetrical factorial design (2000) (28)
Modelling heterocyclic azo dye affinities for cellulose fibres by computational approaches (2012) (28)
Fatty-acid profiling vs UV-Visible fingerprints for geographical classification of Moroccan Argan oils (2019) (27)
Determination of uncertainty in analytical measurements from collaborative study results on the analysis of a phenoxymethylpenicillin sample (2003) (27)
Enantiomeric impurity determination in capillary electrophoresis using a highly-sulfated cyclodextrins-based method. (2006) (27)
Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis. (2017) (27)
Enantioselective capillary electrophoretic separation of tryptophane- and tyrosine-methylesters in a dual system with a tetra-oxadiaza-crown-ether derivative and a cyclodextrin. (2005) (27)
Development and validation of a normal-phase high-performance thin layer chromatographic method for the analysis of sulfamethoxazole and trimethoprim in co-trimoxazole tablets. (2009) (27)
Characterization of different olive pulp and kernel oils (2012) (27)
Study of method validation criteria in a capillary electrophoresis method for the separation of non-steroidal anti-inflammatory drugs (2000) (26)
The application of Kohonen neural networks to diagnose calibration problems in atomic absorption spectrometry. (2000) (26)
Two new c-glucosyl benzoic acids and flavonoids from Mallotus nanus and their antioxidant activity (2010) (26)
Isotopic ratios to detect infringements of patents or proprietary processes of pharmaceuticals: two case studies. (2008) (26)
Nested designs in ruggedness testing. (1999) (25)
Development of a generic flow injection analysis method for compounds with a secondary amine or amide function, using an experimental design approach: I. Selection and evaluation of the FIA system parameters (2001) (25)
Phytotoxic activities of essential oils and hydrosols of Haplophyllum tuberculatum. (2017) (25)
In vitro antileishmanial and cytotoxicity activities of essential oils from Haplophyllum tuberculatum A. Juss leaves, stems and aerial parts (2018) (25)
Robustness testing of a chiral NACE method for R-timolol determination in S-timolol maleate and uncertainty assessment from quantitative data. (2007) (24)
Influence of the sequence of experiments in a ruggedness test when drift occurs (1997) (24)
Strategy for the chiral separation of non‐acidic pharmaceuticals using capillary electrochromatography (2005) (24)
Prediction and interpretation of the antioxidant capacity of green tea from dissimilar chromatographic fingerprints. (2010) (24)
Improved variable reduction in partial least squares modelling by Global-Minimum Error Uninformative-Variable Elimination. (2017) (24)
Interlaboratory study of a liquid chromatography method for erythromycin: determination of uncertainty. (2003) (24)
Development and validation of a high-performance liquid chromatographic method for the determination of gamma-hydroxybutyric acid in rat plasma. (2001) (24)
Comparative enantioseparations of pharmaceuticals in capillary electrochromatography on polysaccharide‐based chiral stationary phases containing selectors with or without chlorinated derivatives (2010) (24)
Interlaboratory study of a NACE method for the determination of R‐timolol content in S‐timolol maleate: Assessment of uncertainty (2006) (23)
Ruggedness tests on the high performance liquid chromatography assay of the United States Pharmacopoeia 23 for tetracycline.HCl: comparison of different columns in an interlaboratory approach. (1996) (23)
A strategy for the development of UV-ELS fingerprints for Ginkgo biloba extracts (2006) (23)
Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy. (2017) (23)
Potentially antidiabetic and antihypertensive compounds identified from Pistacia atlantica leaf extracts by LC fingerprinting (2018) (23)
Detection of adulteration in Chinese monofloral honey using 1H nuclear magnetic resonance and chemometrics (2020) (22)
Accuracy profiles assessing the validity for routine use of high-performance thin-layer chromatographic assays for drug formulations. (2013) (22)
Predictive-property-ranked variable reduction in partial least squares modelling with final complexity adapted models: comparison of properties for ranking. (2013) (22)
Classification models for neocryptolepine derivatives as inhibitors of the β-haematin formation. (2011) (22)
Derivation of system suitability test limits from a robustness test on an LC assay with complex antibiotic samples. (2002) (21)
Monolithic silica capillary columns with immobilized cellulose tris(3,5‐dimethylphenylcarbamate) for enantiomer separations in CEC (2009) (21)
Contribution of the polymer standards' polydispersity to the observed band broadening in size-exclusion chromatography. (2003) (21)
Improving the capillary electrophoretic analysis of poliovirus using a Plackett-Burman design. (2009) (21)
Discrimination and classification techniques applied on Mallotus and Phyllanthus high performance liquid chromatography fingerprints. (2015) (21)
Analysis of erythromycin and benzoylperoxide in topical gels by liquid chromatography. (2003) (21)
Polyphenolic contents, antioxidant activities and UPLC-ESI-MS analysis of Haplophyllum tuberculatum A. Juss leaves extracts. (2018) (21)
Fatty Acids-Based Quality Index to Differentiate Worldwide Commercial Pistachio Cultivars (2018) (21)
Stationary phases in the screening of drug/impurity profiles and in their separation method development: identification of columns with different and similar selectivities. (2006) (20)
Chemical Composition, Antioxidant Properties and Antimicrobial Activity of the Essential Oil of Murraya Paniculata Leaves from the Mountains of Central Cuba (2012) (20)
Interlaboratory studies on two high-performance liquid chromatographic assays for tylosin (tartrate) (1999) (20)
Evaluation of anti-inflammatory activity of the methanolic extract from Jungia rugosa leaves in rodents. (2015) (20)
Predictive-property-ranked variable reduction with final complexity adapted models in partial least squares modeling for multiple responses. (2013) (20)
Binary classification of chalcone derivatives with LDA or KNN based on their antileishmanial activity and molecular descriptors selected using the Successive Projections Algorithm feature-selection technique. (2014) (20)
Potentially antioxidant compounds indicated from Mallotus and Phyllanthus species fingerprints. (2012) (20)
First characterizations by capillary electrophoresis of human Chorionic Gonadotropin at the intact level. (2019) (20)
Bilinear decomposition based alignment of chromatographic profiles. (2012) (19)
Strategy for reduced calibration sets to develop quantitative structure-retention relationships in high-performance liquid chromatography. (2009) (19)
Chapter 6 Optimization strategies for HPLC and CZE (2000) (19)
Quantitative determination of p-aminosalicylic acid and its degradation product m-aminophenol in pellets by ion-pair high-performance liquid chromatography applying the monolithic Chromolith Speedrod RP-18e column. (2004) (19)
Dissimilar chromatographic systems to indicate and identify antioxidants from Mallotus species. (2011) (18)
Study of different criteria for the selection of a rugged optimum in high performance liquid chromatography optimisation (1997) (18)
Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: effect of the incubation medium. (2005) (18)
An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples. (2016) (18)
Dissimilar or orthogonal reversed-phase chromatographic systems: A comparison of selection techniques. (2008) (18)
Inclusion Complexation of Lorazepam with Different Cyclodextrins Suitable for Parenteral Use (2005) (18)
Preparation and in-vitro release rate of fentanyl-cyclodextrin complexes for prolonged action in epidural analgesia. (2003) (18)
Exploring and modelling the responses of electrospray and atmospheric pressure chemical ionization techniques based on molecular descriptors (2005) (18)
Direct orthogonal signal correction as data pretreatment in the classification of clinical lots of creams from near infrared spectroscopy data. (2007) (18)
The use of chemometrics to study multifunctional indole alkaloids from Psychotria nemorosa (Palicourea comb. nov.). Part I: Extraction and fractionation optimization based on metabolic profiling. (2016) (18)
Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice. (2009) (18)
Chemical Analysis and Antioxidant Activity of the Essential Oils of Three Piperaceae Species Growing in the Central Region of Cuba (2013) (17)
The use of chemometrics to study multifunctional indole alkaloids from Psychotria nemorosa (Palicourea comb. nov.). Part II: Indication of peaks related to the inhibition of butyrylcholinesterase and monoamine oxidase-A. (2016) (17)
Robust calibrations on reduced sample sets for API content prediction in tablets: definition of a cost-effective NIR model development strategy. (2013) (17)
Multivariate data analysis to evaluate the fingerprint peaks responsible for the cytotoxic activity of Mallotus species. (2012) (17)
Linear and nonlinear quantitative structure-activity relationship modeling of the HIV-1 reverse transcriptase inhibiting activities of thiocarbamates. (2011) (17)
Enantioseparations by capillary electro‐chromatography: Differences exhibited by normal‐ and reversed‐phase versions of polysaccharide stationary phases (2004) (17)
Quality Control of Herbal Medicines: From Traditional Techniques to State-of-the-art Approaches (2021) (17)
Emerging analytical separation techniques with high throughput potential for pharmaceutical analysis, part I: Stationary phase and instrumental developments in LC. (2010) (17)
Investigation of the effect of mobile phase composition on selectivity using a solvent‐triangle based approach in achiral SFC (2017) (17)
DEVELOPMENT AND VALIDATION OF AN HPLC METHOD WITH POST-COLUMN DERIVATISATION FOR ASSAY OF N-ACETYLCYSTEINE IN PLASMA (2004) (17)
Evaluating "fast" micellar monolithic liquid chromatography for high-throughput quantitative structure-retention relationship screening. (2004) (17)
Statistical method comparison: short- and long-column liquid chromatography assays of ketoconazole and formaldehyde in shampoo (2004) (16)
The molecular descriptor logSumAA and its alternatives in QSRR models to predict the retention of peptides. (2009) (16)
LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins (2016) (16)
Recognizing paracetamol formulations with the same synthesis pathway based on their trace-enriched chromatographic impurity profiles. (2009) (16)
Fast monolithic micellar liquid chromatography: an alternative drug permeability assessing method for high-throughput screening. (2004) (16)
Support Vector Regression Based QSPR for the Prediction of Retention Time of Peptides in Reversed-Phase Liquid Chromatography (2014) (16)
RTS, a computer program for the experimental set-up and interpretation of ruggedness tests. (1998) (16)
Chemical constituents of Mallotus macrostachyus growing in Vietnam and cytotoxic activity of some cycloartane derivatives (2011) (16)
Ultrasound-assisted extraction optimization and validation of an HPLC-DAD method for the quantification of polyphenols in leaf extracts of Cecropia species (2019) (16)
Optimisation of the chlorthalidone chiral separation by capillary electrochromatography using an achiral stationary phase and cyclodextrin in the mobile phase (2004) (16)
Capillary methods for drug analysis. (2011) (16)
Anti-Cancer Activity of Curcumin on Multiple Myeloma. (2020) (16)
Monolithic stationary phases in classic and chiral pharmaceutical analysis with CEC and pCEC. (2009) (16)
Antiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids (2017) (16)
Method optimization for drug impurity profiling in supercritical fluid chromatography: Application to a pharmaceutical mixture. (2017) (15)
Pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves. (2018) (15)
Characterizing and optimizing magnetosome production of Magnetospirillum sp. XM-1 isolated from Xi'an City Moat, China. (2015) (15)
Exploratory data analysis as a tool for similarity assessment and clustering of chiral polysaccharide-based systems used to separate pharmaceuticals in supercritical fluid chromatography. (2014) (15)
Supersaturated designs: set-ups, data interpretation, and analytical applications (2008) (15)
Experimental design methodologies in the optimization of chiral CE or CEC separations: an overview. (2013) (15)
Influence of peak measurement parameters on the quality of chiral electrophoretic separations (2003) (15)
Particle swarm optimization and genetic algorithm as feature selection techniques for the QSAR modeling of imidazo[1,5‐a]pyrido[3,2‐e]pyrazines, inhibitors of phosphodiesterase 10A (2013) (15)
Updating a chiral separation strategy for non‐acidic drugs with capillary electrochromatography applicable for both chlorinated and non‐chlorinated polysaccharide selectors (2011) (15)
Identification of poliovirions and subviral particles by capillary electrophoresis (2010) (15)
Aqueous size-exclusion chromatographic separations of intact proteins under native conditions: Effect of pressure on selectivity and efficiency. (2016) (15)
The evaluation of two‐step multivariate adaptive regression splines for chromatographic retention prediction of peptides (2007) (15)
Optimization of the chiral separation of some 2-arylpropionic acids on an avidin column by modeling a combined response. (2001) (15)
Enantioselectivity of monolithic silica stationary phases immobilized with different concentrations cellulose tris (3,5‐dimethylphenylcarbamate), analyzed with different mobile phases in capillary electrochromatography (2011) (14)
Robustness tests on the United States Pharmacopoeia XXVI HPLC assay for ginsenosides in Asian and American ginseng using an experimental design (2005) (14)
Collaborative study of an liquid chromatographic method for the determination of R-timolol and other related substances in S-timolol maleate (2005) (14)
Evaluation of boosted regression trees (BRTs) and two‐step BRT procedures to model and predict blood‐brain barrier passage (2007) (14)
In vivo anti-inflammatory response and bioactive compounds' profile of polyphenolic extracts from edible Argan oil (Argania spinosa L.), obtained by two extraction methods. (2019) (14)
Development and optimisation of a flow injection assay for fluticasone propionate using an asymmetrical design and the variable-size simplex algorithm. (2000) (14)
Direct profiling of endogenous metabolites in rat brain microdialysis samples by capillary electrophoresis-mass spectrometry with on-line preconcentration (2020) (14)
Uncertainty assessment from robustness testing applied on an LC assay for R-timolol and other related substances in S-timolol maleate (2005) (14)
The variance of screening and supersaturated design results as a measure for method robustness (2005) (13)
Precision evaluation of chiral capillary electrophoretic methods in the context of inter-instrumental transfer: constant current versus constant voltage application. (2014) (13)
Modelling approaches for chiral chromatography on polysaccharide-based and macrocyclic antibiotic chiral selectors: A review. (2021) (13)
Extra virgin Argan oils’ shelf-life monitoring and prediction based on chemical properties or FTIR fingerprints and chemometrics (2021) (13)
Comparison of a triple-quadrupole and a quadrupole time-of-flight mass analyzer to quantify 16 opioids in human plasma. (2016) (13)
Micellar liquid chromatography for lipophilicity determination of new biologically active 1,3-purinodiones. (2010) (13)
Resolution of spectrally rank‐deficient multivariate curve resolution: alternating least squares components in comprehensive two‐dimensional liquid chromatographic analysis (2012) (13)
Investigation of the effect of column temperature and back-pressure in achiral supercritical fluid chromatography within the context of drug impurity profiling. (2017) (13)
Efficient recovery of electrophoretic profiles of nucleoside metabolites from urine samples by multivariate curve resolution (2009) (12)
Drug impurity profiling: Method optimization on dissimilar chromatographic systems: Part I: pH optimization of the aqueous phase. (2009) (12)
Experimental Design in Method Optimization and Robustness Testing (2009) (12)
Ruggedness testing of a size-exclusion chromatographic assay for low-molecular-mass polymers (1996) (12)
Chemometrical exploration of an isotopic ratio data set of acetylsalicylic acid (2005) (12)
Identification of some Bioactive Metabolites in a Fractionated Methanol Extract from Ipomoea aquatica (Aerial Parts) through TLC, HPLC, UPLC-ESI-QTOF-MS and LC-SPE-NMR Fingerprints Analyses. (2018) (12)
Evaluation of polymeric methacrylate-based monoliths in capillary electrochromatography for their potential to separate pharmaceutical compounds. (2007) (12)
Preparation and evaluation of paclitaxel-containing liposomes. (2007) (12)
Enantiomeric impurity determination of levetiracetam using capillary electrochromatography. (2006) (12)
Modelling the quality of enantiomeric separations based on molecular descriptors (2006) (12)
Poliovirus separation from cell extracts using capillary electrophoresis: potential use in vaccine production and control? (2012) (12)
Inclusion complexation of diazepam with different cyclodextrins in formulations for parenteral use. (2005) (12)
Screening approaches for chiral separations. (2008) (12)
Use of experimental design to optimise a flow injection analysis assay for L-N-monomethylarginine. (1999) (12)
Assessing the suitability of capillary electrophoresis‐mass spectrometry for biomarker discovery in plasma‐based metabolomics (2019) (12)
Is the solvation parameter model or its adaptations adequate to account for ionic interactions when characterizing stationary phases for drug impurity profiling with supercritical fluid chromatography? (2016) (12)
A comprehensive strategy using chromatographic profiles combined with chemometric methods: Application to quality control of Polygonum cuspidatum Sieb. et Zucc. (2016) (11)
Critical analysis of the SCCNFP/SCCP safety assessment of cosmetic ingredients (2000-2006). (2009) (11)
Sensitive targeted methods for brain metabolomic studies in microdialysis samples. (2018) (11)
Agglomeration of mesoporous silica by melt and steam granulation. part II: screening of steam granulation process variables using a factorial design. (2013) (11)
Evaluation of data preprocessings for the comparison of GC-MS chemical profiles of seized cannabis samples. (2020) (11)
Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa. (2020) (11)
Identification of significant effects from an experimental screening design in the absence of effect sparsity. (2009) (11)
Selection of orthogonal reversed-phase HPLC systems by univariate and auto-associative multivariate regression trees. (2005) (11)
Development and validation of an ion-exchange chromatography method for heparin and its impurities in heparin products. (2014) (10)
Precision study on capillary electrophoresis methods for metacycline (2006) (10)
Flavonoids from Boldoa purpurascens inhibit proinflammatory cytokines (TNF‐α and IL‐6) and the expression of COX‐2 (2018) (10)
Screening designs: Part 2 - Data analysis (2008) (10)
Modelling the quality of enantiomeric separations using Mutual Information as an alternative variable selection technique. (2007) (10)
UPLC–PDA‐ESI–QTOF–MS/MS and GC‐MS analysis of Iranian Dracocephalum moldavica L. (2021) (10)
Influence of preparation method on itraconazole oral solutions using cyclodextrins as complexing agents. (2007) (10)
Multivariate statistical process control in product quality review assessment - A case study. (2017) (9)
Evaluation of the identification power of RPLC analyses in the screening for drug compounds. (2010) (9)
Raman model development for the protein conformational state classification in different freeze-dried formulations. (2014) (9)
Emerging analytical separation techniques with high-throughput potential for pharmaceutical analysis, part II: Novel chromatographic modes. (2010) (9)
New insights into the Argan oil categories characterization: Chemical descriptors, FTIR fingerprints, and chemometric approaches. (2021) (9)
Rational use of stacking principles for signal enhancement in capillary electrophoretic separations of poliovirus samples. (2011) (9)
Influence of the polymerization-mixture composition for monolithic methacrylate-based columns on the electrochromatographic performance of drug molecules. (2008) (9)
Screening of an enterovirus specific RT-PCR ELISA method for the quantification of enterovirus genomes in human body fluids by means of a three-level experimental design. (2001) (8)
Optimisation of the reversed phase liquid chromatographic separation of atovaquone, proguanil and related substances. (1997) (8)
Chemometrics in Chromatography (2018) (8)
High-throughput screening and optimization approaches for chiral compounds by means of microfluidic devices. (2007) (8)
A new flavone sulfonic acid from Phyllanthus urinaria (2014) (8)
Fixing Effects and Adding Rows (FEAR) method to estimate factor effects in supersaturated designs constructed from Plackett–Burman designs (2007) (8)
Broad-spectrum separations in metabolomics using enhanced polar LC stationary phases: a dedicated evaluation using plant metabolites. (2007) (8)
CE-MS metabolic profiling of volume-restricted plasma samples from an acute mouse model for epileptic seizures to discover potentially involved metabolomic features. (2020) (8)
Study of the antioxidant activity of Pistacia atlantica Desf. Gall extracts and evaluation of the responsible compounds (2022) (8)
Comparison of the miniaturised techniques capillary electrochromatography and capillary liquid chromatography for the chiral separation of chlorthalidone. (2004) (7)
Inter-instrumental method transfer of chiral capillary electrophoretic methods using robustness test information. (2014) (7)
Natural plant toxins in honey: An ignored threat to human health. (2021) (7)
Antioxidant and anticandidal activities of the Tunisian Haplophyllum tuberculatum (Forssk.) A. Juss. essential oils (2017) (7)
Development and Validation of a Normal-Phase HPTLC-Densitometric Method for the Quantitative Analysis of Fluconazole in Tablets (2011) (7)
Affinity capillary electrophoresis to evaluate the complex formation between poliovirus and nanobodies. (2014) (7)
Potential antioxidant compounds in Mallotus species fingerprints. Part I: indication, using linear multivariate calibration techniques. (2009) (7)
Three promising antimycobacterial medicinal plants reviewed as potential sources of drug hit candidates against multidrug-resistant tuberculosis. (2020) (6)
Anti-inflammatory and sedative activities of Peperomia galioides: in vivo studies in mice (2019) (6)
Newly synthesized tetraoxa-diaza crown ether derivatives versus commercialized crown ethers in the separation of positional isomers with capillary electrophoresis. (2006) (6)
Detection, interpretation and correction of changes in the instrumental response of near-infrared monochromator instruments over time (1997) (6)
Fast and Simultaneous Analysis of Combined Anti-Diabetic Drugs by Capillary Zone Electrophoresis. (2015) (6)
Method development for drug impurity profiling: Part 2 (2010) (6)
Feasibility study on exhaled-breath analysis by untargeted Selected-Ion Flow-Tube Mass Spectrometry in children with cystic fibrosis, asthma, and healthy controls: Comparison of data pretreatment and classification techniques. (2021) (6)
A new potential anti‐cancer beta‐carboline derivative decreases the expression levels of key proteins involved in glioma aggressiveness: A proteomic investigation (2020) (6)
Two New Megastigmane Sulphonoglucosides from Mallotus anisopodus (2009) (6)
Recent developments in liquid and supercritical fluid chromatographic enantioseparations (2020) (6)
A New Lignan Dimer from Mallotus philippensis (2010) (6)
Screening and optimisation of an ELISA method for the quantitative detection of enterovirus specific RT-PCR products by means of a two-level experimental design. (2002) (6)
Evaluation of a generalized use of the log Sum(k+1)AA descriptor in a QSRR model to predict peptide retention on RPLC systems. (2009) (6)
Detection Systems for Microfluidic Devices with a Major Focus on Pharmaceutical and Chiral Analysis (2009) (6)
Modeling of Peak Shape and Asymmetry (2018) (6)
Application of Rank Annihilation Factor Analysis for Antibacterial Drugs Determination by Means of pH Gradual Change-UV Spectral Data (2020) (6)
Pressure‐assisted CEC versus CEC using methacrylate‐based monolithic columns: Influence of the polymerization‐mixture composition (2008) (6)
Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. (2017) (6)
Interinstrumental method transfer of a capillary electrophoretic separation of angiotensin II and five derivatives: Evaluation and update of earlier developed guidelines (2015) (6)
Screening designs: Part 1 - Types and properties (2007) (6)
N-methyl-5-carboxamide-2-pyridone from Mallotus barbatus: A chemosystematic marker of the Euphorbiaceae genus Mallotus (2012) (6)
Interinstrumental Transfer of a Chiral Capillary Electrophoretic Method: The Use of Robustness Test Information to Overcome Differences in Detector and Data-Handling Specifications (2018) (6)
A Study of the Effects of pH and Water Activity on the N-Nitrosopiperidine Formation in a Protein-Based Liquid System (2014) (6)
Parallel co-ordinate geometry and principal component analysis for the interpretation of large multi-response experimental designs (2002) (6)
Three versus five micrometer chlorinated polysaccharide-based packings in chiral capillary electrochromatography: efficiency and precision evaluation. (2014) (6)
Experimental Design Methodologies for the Optimization of Chiral Separations: An Overview. (2019) (6)
18 – Chiral Separations (2005) (5)
Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability. (2012) (5)
Impact of the sample matrix composition on the signal enhancement in the capillary electrophoretic separation of poliovirus samples. (2012) (5)
Response surface designs: Part 1 - Types and properties (2009) (5)
Pressurized capillary electrochromatography in a screening for possible antioxidant molecules in Mallotus fingerprints: challenges, potentials and prospects. (2011) (5)
Chemical stability of artemisinin derivatives (2012) (5)
Rendering A Chiral Screening Step In Supercritical Fluid Chromatography Mass-Spectrometry Compatible. (2020) (5)
Identification by LC-ESIMS of Flavonoids Responsible for the Antioxidant Properties of Mallotus Species from Vietnam (2011) (5)
Test-set reduction in the screening step definition of a chiral separation strategy in polar organic solvents chromatography. (2012) (5)
Improvement of quantitative structure-retention relationship models for chromatographic retention prediction of peptides applying individual local partial least squares models. (2020) (5)
9 Robustness testing of CE methods (2008) (5)
Pressurized capillary electrochromatographic assay of trimethoprim impurities using 1 microm particle-based columns. (2007) (5)
Development of an Omeprazole Parenteral Formulation with Hydroxypropyl-β-Cyclodextrin (2007) (5)
Separation from related compounds and assay of calcipotriol by high-performance liquid chromatography. (1998) (5)
LC separation of calcipotriol from its photodegradation products and protection possibilities using adjuvants. (2001) (5)
Investigation of the chiral separation of cisapride on Chiralcel OJ and OJ-R columns (2003) (5)
Defining a standardized methodology for the determination of the antioxidant capacity: case study of Pistacia atlantica leaves. (2019) (5)
Fingerprint development for Ginkgo biloba extracts by pressurized capillary electrochromatography: comparison of column types. (2010) (5)
Sequential Optimization Methods (2020) (5)
MODELLING OF SOLUTE RETENTION IN THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY SYSTEM WITH THE CHEMICALLY BONDED 3-CYANOPROPYL STATIONARY PHASE (1999) (5)
Kinetic study of niobium and tantalum hexameric forms and their substituted ions by capillary electrophoresis in alkaline medium. (2017) (5)
All that glitters is not gold: Panning cytotoxic natural products and derivatives with a fused tricyclic backbone by the estimation of their leadlikeness for cancer treatment. (2019) (5)
Cytotoxicity and Antiviral Activities of Haplophyllum tuberculatum Essential Oils, Pure Compounds, and Their Combinations against Coxsackievirus B3 and B4 (2021) (5)
N-acetylcysteine and cardiac dysfunction in human septic shock (2002) (5)
Modeling of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one derivatives by several conformational searching tools and molecular docking. (2013) (5)
Chemometric selection of a small set of pharmaceutical active substances used in determining the orthogonality and similarity of chromatographic systems (2006) (5)
In vitro antimycobacterial activity of medicinal plants Lantana camara, Cryptolepis sanguinolenta, and Zanthoxylum leprieurii (2022) (5)
Gallium-67 Citrate Whole Body Scanning for the Localization of Infected Vascular Synthetic Grafts (1985) (5)
Authentication of extra virgin Argan oil by selected-ion flow-tube mass-spectrometry fingerprinting and chemometrics. (2022) (4)
Improved modelling for low-correlated multiple responses by common-subset-of-independent-variables partial-least-squares. (2021) (4)
Three versus five micrometer chlorinated polysaccharide-based packings in chiral capillary electrochromatography: performance evaluation. (2014) (4)
Separation of Stereoisomers (2017) (4)
Effects of growing region and maturity stages on oil yield, fatty acid profile and tocopherols of Pistacia atlantica Desf. fruit and their implications on resulting biodiesel (2022) (4)
Pharmaceutical analysis combined with in-silico therapeutic and toxicological profiling on zileuton and its impurities to assist in modern drug discovery. (2019) (4)
The effect of anionic surfactant on poliovirus particles during capillary electrophoresis. (2012) (4)
Generalized FEAR method to estimate factor effects in two‐level supersaturated designs (2007) (4)
Validation of Thin Layer Chromatographic Methods (2014) (4)
Role of cadaverine and piperidine in the formation of N-nitrosopiperidine in heated cured meat (2010) (4)
Assessing mixtures of supercharging agents to increase the abundance of a specific charge state of Neuromedin U. (2019) (4)
Characterisation of reversed phase liquid chromatographic columns by chromatographic tests. Preliminary experiments and development of the protocol (2002) (4)
LC‐method development for the quantification of neuromedin‐like peptides. Emphasis on column choice and mobile phase composition (2017) (4)
Improved multi-class discrimination by Common-Subset-of-Independent-Variables Partial-Least-Squares Discriminant Analysis. (2021) (3)
Multifunctional Monoamine Oxidases and Cholinesterases Inhibitory Effects, as well as UPLC-DAD-MS Chemical Profile of Alkaloid Fractions Obtained from Species of the Palicoureeae Tribe (2016) (3)
High‐Throughput Screening and Method Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE (2010) (3)
Evaluation of orthogonal/dissimilar RP-HPLC systems sets for their suitability as method-development starting points for drug impurity profiles. (2008) (3)
A label-free detector for liquid chromatography systems using mm-wave technology: First proof of concept. (2017) (3)
Modelling of solute retention in normal-phase HPLC with the chemically bonded 3-cyanopropyl stationary phase (1998) (3)
Secondary-metabolites fingerprinting of Argania spinosa kernels using liquid chromatography-mass spectrometry and chemometrics, for metabolite identification and quantification as well as for geographic classification. (2022) (3)
Capillary electrochromatographic testing of monolithic silica columns synthesized according to an experimental design approach. (2011) (3)
Interinstrumental transfer of a fast short‐end injection capillary electrophoresis method: Application to the separation of niobium, tantalum, and their substituted ions (2017) (3)
Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide-based chiral stationary phases. (2014) (3)
Data handling software for a GLP environment: development and validation requirements (2006) (3)
POSTER: Validation and comparison of Plackett-Burman and supersaturated designs in robustness testing of a FIA assay (2006) (3)
Stationary-phase optimized selectivity in supercritical fluid chromatography using a customized Phase OPtimized Liquid Chromatography kit: comparison of different prediction approaches (2020) (3)
Chemometrics and Modeling (2001) (3)
In Vitro & In Vivo Anti-Hyperglycemic Potential of Saponins Cake and Argan Oil from Argania spinosa (2021) (3)
Predicting skin permeability of pharmaceutical and cosmetic compounds using retention on octadecyl, cholesterol-bonded and immobilized artificial membrane columns. (2022) (3)
Capillary Electrophoresis in Chiral Separations (2013) (2)
Comparison of in-silico modelling and reversed-phase liquid chromatographic retention on an octadecyl silica column to predict skin permeability of pharmaceutical and cosmetic compounds. (2021) (2)
Fabrication of A Molecularly Imprinted Monolithic Column Via the Epitope Approach For the Selective Capillary Microextraction of Neuropeptides In Human Plasma (2022) (2)
Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: actual status and the way forward (2021) (2)
Total Error-Based Validation Including the Experimental Design-Based Robustness Evaluation of a Stability-Indicating Method for the Simultaneous Quantification of Hydrochlorothiazide and Valsartan in Tablet Formulations (2015) (2)
Phenolic Compounds Profile from Algerian Pomegranate Fruit Extract (Punica Granatum L.) by UPLC-DAD-ESI-MS (2022) (2)
Fabrication of a molecularly imprinted monolithic column via the epitope approach for the selective capillary microextraction of neuropeptides in human plasma. (2022) (2)
Application of Zebrafish embryos toxicity test to evaluate the alkaloid fraction of Psychotria deflexa (2015) (2)
Gas Chromatographic Fingerprint Analysis for the Comparison of Seized Cannabis Samples (2021) (2)
Response surface designs: Part 2 - Data analysis and Multiresponse optimisation (2009) (2)
Normal‐Phase and Polar Organic Solvents Chromatography (2015) (2)
Cytotoxic, Antioxidant, and Antidiabetic Activities versus UPLC-ESI-QTOF-MS Chemical-Profile Analysis of Ipomoea aquatica Fractions (2021) (2)
Evaluating micellar liquid chromatographic methods on octadecyl particle-based and monolithic columns to predict the skin permeation of drug and cosmetic molecules (2021) (2)
Skills development by project-based education in the food and diet course of a pharmacy program (2007) (2)
Composition and antioxidant activities of the essential oil of Murraya paniculata leaves growing wild in Cubans mountain (2011) (2)
CHAPTER IN BOOK: Experimental design in method optimization an robustness testing (2010) (2)
Chemometric modelling of the catalytic hydrogenation of bicarbonate to formate in aqueous media (2004) (2)
What can chemometrics do for separation science (2004) (1)
Validation of gas chromatographic methods (2021) (1)
Chemical stability of artemisinin derivatives (2012) (1)
Coupling of chiral and achiral stationary phases in supercritical fluid chromatography: Evaluating and improving retention prediction. (2022) (1)
Statistics in Validation of Quantitative Chromatographic Methods (2018) (1)
Experimental design in chromatographic method development and validation. (2018) (1)
CHAPTER IN BOOK: Sequential optimization methods (2009) (1)
Assessment of accuracy in chromatographic analysis (2008) (1)
Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans (2022) (1)
Defining a system suitability limit to decide on column deterioration and to facilitate column transfers in chiral supercritical fluid chromatography (2019) (1)
Recent trends in pharmaceutical analysis to foster modern drug discovery by comparative in-silico profiling of drugs and related substances (2022) (1)
Pharmaceutical and Herbal Fingerprinting by Means of Chromatographic Techniques (2012) (1)
Impact of proline, hydroxyproline, and pyrrolidine on the N-nitrosopyrrolidine formation in heated cured meat products (2009) (1)
Development of an adverse outcome pathway network for breast cancer: a comprehensive representation of the pathogenesis, complexity and diversity of the disease (2022) (1)
CHAPTER IN BOOK: Chromatographic development, validation, and data handling of tea fingerprints (2013) (1)
Direct Orthogonal Signal Correction as Preprocessing Technique for near Infrared Applications (2008) (1)
Column selection in pharmaceutical analysis based on column classification using 4 test parameters (2005) (1)
Chromatography: Supercritical Fluid Chromatography (2016) (1)
Development of a capillary electrophoresis method for the separation of flavonolignans in silymarin complex (2021) (1)
Cleaning validation of biologicals: Determination of a worst-case product for RTH 258 (2021) (1)
Kopsanone and N(4)-oxide-kopsanone: two β-carbolinic indole alkaloids with monoamine oxidase A inhibitory activity (2015) (1)
Optimized mobile phase for CEC of acetylsalicylic acid and its impurities using a methacrylate-based monolithic column. (2011) (1)
Mutual Information for the selection of variables to model enantioselectivity (2006) (1)
POSTER: Comparing different descriptor selection strategies in QSRR to predict the chromatographic retention of diverse drugs (2010) (0)
ORAL PRES.: Herbal fingerprints: development and extraction of information (2011) (0)
POSTER: FEAR method to estimate factor effects in supersaturated designs constructed from Plackett-Burman designs (2006) (0)
Discrimination and classification study of Mallotus and Phyllanthus genera and species based on their HPLC-UV fingerprints (2014) (0)
Determination of uncertainty in a liquid chromatographic method for erythromycin from Interlaboratory study results (2003) (0)
POSTER: Tools for semi-supervised classification (2012) (0)
POSTER: Pressurized capillary electrochromatography, a useful technique to screen for antioxidant compounds in Mallotus fingerprints? (2009) (0)
ORAL PRES.: Identification of peaks from HPLC fingerprints responsible for the antioxidant activity of Mallotus species (2008) (0)
POSTER: Screening for antioxidant compounds in Mallotus species using partial least squares regression models built on pressurized capillary electrochromatography fingerprints (2009) (0)
POSTER: Effects of growing region and maturity stages on lipid yield, fatty acid profile and tocopherols of Pistacia atlantica fruit and implications on resulting biodiesel (2014) (0)
POSTER: Chiral separations in supercritical fluid chromatography: update of a generic screening step. (2012) (0)
INTERNATIONAL LECTURE/COURSE/ORAL PRES. ON INVITATION: Introductory Course to Chemometrics: Experimental Design and Multivariate Data Analysis (2010) (0)
Improving the LC-MS/MS analysis of neuromedin U-8 and neuromedin S by minimizing their adsorption behavior and optimizing UHPLC and MS parameters. (2023) (0)
Optimization of extraction conditions for total flavonoids, chlorogenic acid and flavolignans contents from Cecropia sp. leaves using design-of-experiments methodology (2017) (0)
POSTER: Understanding the pharmaceutical freeze-drying process: a stepping stone towards quality by design (2010) (0)
POSTER: Uniform designs in method optimization (2011) (0)
ORAL PRES.: Multivariate Data Handling in Pharmaceutical Sciences (2015) (0)
POSTER: Evaluation of sample matrix components affecting the separation efficiency of poliovirus particles in capillary electrophoresis (2008) (0)
ORAL PRES.: HPLC fingerprints from a set of Mallotus and Phyllantus samples for discrimination and classification purposes (2013) (0)
Classification Tree Models for the Prediction of Blood—Brain Barrier Passage of Drugs. (2006) (0)
ORAL PRES.: Development and optimisation of separation methods for viral particles (2010) (0)
Chiral Separations by Capillary Electrophoresis (2010) (0)
ORAL PRES.: Indication and identification of potential antioxidant compounds in Mallotus species fingerprints (2009) (0)
Biophysical Assessment of Skin Desquamation and Scaliness Using Tape Strips and Adhesive Discs (2014) (0)
POSTER: Signal increase using experimental design for a capillary electrophoresis separation of poliovirus particles (2009) (0)
POSTER: Comparing different descriptor selection strategies in QSRR model building to predict the chromatographic retention of diverse drugs (2011) (0)
POSTER: Quality control of Citri reticulatae pericarpium based on chemometrically treated HPLC fingerprints (2010) (0)
International lecture/course: Introductory course on Data Analysis, Optimization Techniques and Chemometrics. (2010) (0)
Constituents and quality control parameters of the vegetable oil from Cucurbita moschata, Duchesne, cultivated in Cuba (2009) (0)
ORAL PRES. ON INVITATION: Multivariate Data Handling in Pharmaceutical Sciences (2015) (0)
Short Lecture “From in silico to in vivo: Psychotria nemorosa alkaloids counter protein toxicity in Caenorhabditis elegans” (2022) (0)
Quality Control and Authentication of Argan Oils: Application of Advanced Analytical Techniques (2023) (0)
POSTER: Separation of poliovirus particles using capillary electrophoresis (2008) (0)
ORAL PRES.: Factors influencing poliovirus focusing during a capillary electrophoresis separation (2009) (0)
POSTER: Plant extracts as antioxidant and antimicrobial agents. (2015) (0)
Analysing mixtures with Curve Resolution: applications of OPA (2003) (0)
POSTER: Coupling columns in SFC under isocratic conditions and retention prediction - 'PRISMA' approach. (2016) (0)
POSTER: Precision optimisation of chiral capillary electrophoretic methods: constant current mode (2013) (0)
[Tests for robustness of biomedical and pharmaceutical analytic methods]. (2003) (0)
Determination of uncertainty in a LC method for erythromycin from interlaboratory results (2003) (0)
Recent Applications in Capillary Electrochromatography (2009) (0)
Chemical studies and biological investigations of Vietnamese plants and herbal medicines from the Euphorbiaceae family to develop high-value healthcare materials and their quality control : final report (2016) (0)
Liquid Chromatography for Plant Metabolite Profiling in the Field of Drug Discovery (2018) (0)
Characterisation and classification of reversed-phase liquid chromatographic columns (2004) (0)
Ultrasound-assisted extraction optimization and validation of an HPLC-DAD method for the quantification of polyphenols in leaf extracts of Cecropia species (2019) (0)
Identification of polyphenols responsible for antioxidant properties and cytotoxic properties of Mallotus species from Vietnam (2010) (0)
LC-MS analysis combined with PCA and SIMCA for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins (2017) (0)
POSTER: Robust modeling of the antioxidant capacity of green tea based on chromatographic fingerprints. (2008) (0)
POSTER: Quality control of Citri reticulatae: exploratory analysis and discrimination (2011) (0)
ORAL PRES.: Robustness testing of HPLC methods (2007) (0)
POSTER: Department Analytical Chemistry and Pharmaceutical Technology (FABI) (2013) (0)
ORAL PRES.: Selection of an orthogonal subset of reversed phase HPLC columns on LC-MS-DAD. (2004) (0)
POSTER: Screening for antioxidant compounds in pressurized capillary electrochromatographic fingerprints from Mallotus species using partial least squares algorithms (2009) (0)
ORAL PRES.: Herbal Fingerprints: Development and Data Analysis. (2013) (0)
POSTER: Chromatographic fingerprints to model the antioxidant activity of Pistacia atlantica leaves extracts in order to identify potential antioxidant markers (2014) (0)
Assessing the actual utility of capillary electrophoresis-mass spectrometry for metabolic profiling of human plasma. (2018) (0)
Exploratory Data Analysis and Classification of Capillary Electrophoretic Data (2009) (0)
Collaborative study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities (2018) (0)
Column classification system, Part 1 : Development (2007) (0)
POSTER: Experimental design optimization of the chiral separation of chlorthalidone by Capillary Electrochromatography using an achiral stationary phase and cyclodextrin in the mobile phase (2002) (0)
ORAL PRES.: Multivariate Statistical Tools applied in Product Quality Review assessment. (2015) (0)
POSTER: Study of the Polygonum influencing PLS discrimination models for Polygonum cuspidatum and Polygonum multiflorum chromatographic fingerprints (2015) (0)
RP-LC column classification study. Part I : Comparing column classification and column performance for seven different separations (2005) (0)
Effects of Growing Region and Maturity Stages on Oil Yield and Fatty Acid Profile of Pistacia Atlantica Desf. Fruit and Their Implications on Resulting Biodiesel (0)
POSTER: Determination of antioxidative compounds in Mallotus species fingerprints using linear multivariate calibration techniques (2008) (0)
POSTER: Inter-instrumental transfer of a chiral CE method using precision studies and robustness testing data, (2013) (0)
CHAPTER IN BOOK: Experimental design methodologies in the optimization of chiral CE or CEC separations (2013) (0)
ORAL PRES.: Pressurized capillary electrochromatography as an alternative technique to high-performance liquid chromatography for the indication of active compounds in Mallotus species (2009) (0)
POSTER: Investigations on the stability of poliovirus in the presence of chemical interfering agents (2010) (0)
POSTER: Screening for critical process parameters in a pharmaceutical freeze-drying process using a Plackett-Burman design and PAT tools (2010) (0)
ORAL PRES.: Comparison of different approaches for the optimization of two parameters of Radial Basis Function – Support Vector Machines for Classification (2012) (0)
ORAL PRES.: Improving MS identification of Bacillus Subtilis delta-prpE and 168 proteins with the use of QSRR-based peptides retention times prediction in RP-HPLC (2010) (0)
Determination of uncertainty in analytical measurements: Collaborative study of the analysis of phenoxymethylpenicillin (2002) (0)
POSTER: Fused-core stationary phases for fingerprint development of Phyllanthus and Mallotus species (2012) (0)
POSTER: Dissimilar chromatographic fingerprints to indicate compounds with antioxidant activity (2009) (0)
Investigation on the photostability of calcipotriol in selected solvents and in the presence of a sunscreen (1998) (0)
ORAL PRES.: Data handling of chromatographic herbal fingerprints (2010) (0)
POSTER: Capillary electrophoresis of poliovirus particles (2008) (0)
POSTER: Chromatographic screening strategies for chiral pharmaceuticals inplemented in a Knowledge-Based System: RPLC and NPLC. (2001) (0)
Antioxidant activities of polyphenols isolated from Mallotus metcalfianus Croizat (2008) (0)
POSTER: Data handling of chromatographic herbal fingerprints (2011) (0)
ORAL PRES.: Precision optimisation of chiral capillary electrophoretic methods: constant current versus constant voltage (2013) (0)
ORAL PRES.: Data analysis of HPLC fingerprints from Mallotus and Phyllanthus samples (2011) (0)
Feature Selection Methods in Qsar Studies Table 1. Different Wrapper and Filter Methods (2012) (0)
ORAL PRES.: Chromatographic fingerprints for herbal extracts as tools for identification or quality control (2012) (0)
harmaceutical-enantiomers resolution using immobilized olysaccharide-based chiral stationary phases in supercritical fluid hromatography (2014) (0)
POSTER: Identification of antioxidative compounds in Mallotus species combining chemometrical treated fingerprints with HPLC-MS (2010) (0)
POSTER : Determination of optimal extraction conditions for Pistacia atlantica leaves using response surface methodology (2015) (0)
POSTER : Potentially antidiabetic compounds identified from Pistacia atlantica leaf extracts by HPLC-MS fingerprints (2015) (0)
ORAL PRES.: Citri reticulatae pericarpium: exploratory analysis and discrimination amongst Citrus species. (2011) (0)
Trends in Pharmaceutical Analysis to Foster Modern Drug Discovery by Comparative In-Silico Profiling of Drugs and Related Substances (2022) (0)
ORAL PRES.: Challenges in capillary electrophoretic analysis of viral particles (2009) (0)
Prediction of antioxidant activity of Mallotus species form HPLC fingerprints (2008) (0)
POSTER: Fluorescent poliovirus analysis with laser induced fluorescent capillary electrophoresis: Labeling efficiency versus viral properties, (2010) (0)
Supersaturated designs in robustness testing: FEAR method to estimate factor effects in two-level supersaturated designs (2008) (0)
POSTER: Transfer of a chiral CE method using precision and robustness testing data (2013) (0)
POSTER: Fluorescence labelling of poliovirus and analysis with laser induced fluorescence capillary electrophoresis (2010) (0)
ORAL PRES.: Experimental Design-Based Method Development and its Translation to Chromatographic Methods (2011) (0)
POSTER: Clean-up of poliovirus samples for capillary electrophoresis analysis using off-line spin-column size-exclusion chromatography (2010) (0)
ORAL PRES.: Capillary electrophoresis of poliovirus particles (2007) (0)
ORAL PRES. ON INVITATION : Analytical applications of experimental designs (2014) (0)
Determination of antioxidative compounds in Mallotus species using linear multivariate calibration techniques (2008) (0)
POSTER: Antioxidant properties of Mallotus species from Vietnamese mountainous areas (2009) (0)
xploratory data analysis as a tool for similarity assessment and lustering of chiral polysaccharide-based systems used to separate harmaceuticals in supercritical fluid chromatography (2014) (0)
POSTER: Process Analytical Technologies: an investment in understanding the pharmaceutical freeze-drying process (2010) (0)
Comparison of supercritical fluid chromatographic methods to predict the skin permeability of pharmaceutical and cosmetic compounds. (2023) (0)
Comparison of Unispray and Electrospray for the ionization of neuropeptides. (2018) (0)
ORAL PRES.: Chromatographic herbal fingerprints: Development, Validation and Data Handling (2011) (0)
ORAL PRES. ON INVITATION : Data handling of chromatographic herbal fingerprints (2012) (0)
POSTER: Fuzzy Rough Set as feature selection for QSAR modeling of 2,4,5-trisubstituted imidazoles, nontoxic modulators of P-glycoprotein mediated multidrug resistance (2011) (0)
POSTER: Fluorescence labeling of Poliovirus and analysis with laser induced capillary electrophoresis (2010) (0)
Chemometric Strategies in Analysis of Chromatographic–Mass Spectrometry Data (2018) (0)
Common Problems with Method Optimisation in Pharmaceutical Analysis (2011) (0)
CHAPTER IN BOOK: Robustness testing of capillary electrophoretic methods (2008) (0)
ORAL PRES.: Assessment of different methods for cleaning up a fluorescent labelled poliovirus sample and analysis with laser induced fluorescent capillary electrophoresis (2010) (0)
ORAL PRES.: Alternative methods for multi-objective optimization of Radial Basis Function - Support Vector Machines for Classification (2013) (0)
ORAL PRES.: Experimental designs for the optimization of analytical techniques (2012) (0)
Analytical strategies for herbal Cannabis samples in forensic applications: A comprehensive review (2023) (0)
POSTER: Development of a quantitative structure-activity relationship: estrogen receptor B ligands (2010) (0)
POSTER: Determination of antioxidative compounds in Mallotus species using multivariate linear calibration techniques (2008) (0)
POSTER: Identification, discrimination and classification of Curcuma samples using their chromatographic fingerprints (2013) (0)
Corrigendum to “Potentially antioxidant compounds indicated from Mallotus and Phyllanthus species fingerprints” [J. Chromatogr. B 910 (2012) 114–121]☆ (2014) (0)
POSTER: Influence of sample matrix composition on the separation efficiency of poliovirus particles in capillary electrophoresis (2008) (0)
16 CE as an orthogonal technique to chromatography (2008) (0)
ORAL PRES.: Signal increase for a capillary electrophoresis separation of poliovirus particles (2009) (0)
Modelling the enantiorecognition of structurally diverse pharmaceuticals on O-substituted polysaccharide-based stationary phases. (2023) (0)
CHAPTER IN BOOK: Validation of gas chromatographic methods (2012) (0)
POSTER: Estimation of factor effects in supersaturated designs - Preliminary Results (2004) (0)
POSTER: Modelling of antioxidant activities of Pistacia atlantica leaves extracts from chromatographic fingerprints and prediction of interesting peaks, (2014) (0)
POSTER: On-line sample preconcentration of poliovirus particles in a capillary electrophoresis method (2008) (0)
ORAL PRES. ON INVITATION : Chromatographic herbal fingerprints: Development, Validation, and Data Handling (2010) (0)
INTERNATIONAL LECTURE/COURSE/ORAL PRES. ON INVITATION : Basic unsupervised and supervised multivariate data analysis (2011) (0)
ORAL PRES. : Quantitation of opioids in human plasma by means of UPLC-MS: triple quadrupole (QqQ) versus quadrupole-time of flight (Q-tof) mass analyzer, (2015) (0)
ORAL PRES.: Herbal Fingerprints: Extraction of Information (2012) (0)
POSTER: Exploring 2D and 3D QSAR models of thiocarbamates, a new class of potent non-nucleosides HIV-1 reverse transcriptase inhibitors (2010) (0)
ORAL PRES.: Chromatographic fingerprints for herbal extracts: set-up and data analysis (2010) (0)
Book of Abstracts CHEMOMETRICS IN ANALYTICAL CHEMISTRY (2013) (0)
ORAL PRES.: Herbal Fingerprints: Extraction of Information, Focussing on Similarity Analyses (2012) (0)
ORAL PRES.: The variance of screening- and supersaturated- design results as a measure for the robustness of a method (2004) (0)
POSTER: Process Understanding and Process Efficiency Increase of Freeze Drying (2008) (0)
POSTER: Identifying significant effects in experimental designs for robustness testing (2005) (0)
ORAL PRES.: Seasonal Discrepancies in Total Phenolic, Flavonoid, Condensed Tannins Contents and in Antioxidant Properties from Pistacia Atlantica Leaves (2013) (0)
ORAL PRES. ON INVITATION : Experimental designs for the optimization of analytical techniques (2011) (0)
Classification of HPLC fingerprints for a set of Mallotus and Phyllanthus samples (2011) (0)
ORAL PRES.: Sample matrix, friend or foe when CE applications are desinged for virus particles ? (2013) (0)
POSTER: Dissimilar chromatographic systems to identify peaks responsible for the antioxidant activity of Mallotus species (2009) (0)
Study of the influence of outliers on discrimination and classification models in a small set of multi-class herbal fingerprints" (2015) (0)

This paper list is powered by the following services:

Other Resources About Yvan Vander Heyden

cris.vub.be

What Schools Are Affiliated With Yvan Vander Heyden?

Yvan Vander Heyden is affiliated with the following schools: