Zaverio M Ruggeri
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Computer Science
Zaverio M Ruggeri's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Zaverio M Ruggeri's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Platelets in atherothrombosis (2002) (1603)
- Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor (1996) (1233)
- Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor (2006) (1060)
- Specific Synergy of Multiple Substrate–Receptor Interactions in Platelet Thrombus Formation under Flow (1998) (850)
- Adhesion Mechanisms in Platelet Function (2007) (625)
- Integrin activation controls metastasis in human breast cancer. (2001) (585)
- 1-DEAMINO-8-D-ARGININE VASOPRESSIN: A NEW PHARMACOLOGICAL APPROACH TO THE MANAGEMENT OF HAEMOPHILIA AND VON WILLEBRAND'S DISEASE (1977) (548)
- Variant von Willebrand's disease: characterization of two subtypes by analysis of multimeric composition of factor VIII/von Willebrand factor in plasma and platelets. (1980) (534)
- Von Willebrand factor, platelets and endothelial cell interactions (2003) (441)
- Platelets have more than one binding site for von Willebrand factor. (1983) (434)
- Heightened interaction between platelets and factor VIII/von Willebrand factor in a new subtype of von Willebrand's disease. (1980) (395)
- Activation-independent platelet adhesion and aggregation under elevated shear stress. (2005) (391)
- The complex multimeric composition of factor VIII/von Willebrand factor. (1981) (371)
- Mechanisms Initiating Platelet Thrombus Formation (1997) (368)
- Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor. (1990) (355)
- Structure and Function of von Willebrand Factor (1992) (348)
- Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. (2006) (348)
- Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells (1989) (329)
- Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. (1992) (325)
- Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. (2000) (320)
- Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. (1998) (316)
- Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress. (2006) (315)
- The role of von Willebrand factor in thrombus formation. (2007) (314)
- Cell damage evaluation of thermal inkjet printed Chinese hamster ovary cells (2010) (303)
- The complex multimeric composition of factor VIII/von Willebrand factor (1981) (303)
- Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets. (1993) (296)
- The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. (2003) (293)
- Characterization of the Unique Mechanism Mediating the Shear-dependent Binding of Soluble von Willebrand Factor to Platelets (*) (1995) (290)
- Contribution of distinct adhesive interactions to platelet aggregation in flowing blood. (1999) (289)
- Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets. (1991) (280)
- von Willebrand factor and von Willebrand disease. (1987) (279)
- Talin is required for integrin-mediated platelet function in hemostasis and thrombosis (2007) (278)
- Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B (2012) (278)
- Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome. (2000) (273)
- Platelets mediate cytotoxic T lymphocyte–induced liver damage (2005) (273)
- Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate. (1989) (266)
- Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet activation. Relationship to the binding of fibrinogen and platelet aggregation. (1987) (260)
- Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells (1996) (255)
- von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib. (1986) (249)
- Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: implications for pathophysiology and therapy of von Willebrand's disease subtypes (1982) (247)
- Immunosurveillance of the Liver by Intravascular Effector CD8+ T Cells (2015) (240)
- Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets. (1982) (231)
- von Willebrand factor. (1997) (226)
- Nucleotide Polymorphisms in the α2 Gene Define Multiple Alleles That Are Associated With Differences in Platelet α2β1 Density (1998) (226)
- Functional self-association of von Willebrand factor during platelet adhesion under flow (2001) (225)
- A Role of the Fast ATP-gated P2X1 Cation Channel in Thrombosis of Small Arteries In Vivo (2003) (222)
- Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE). (1986) (215)
- Platelet Adhesion under Flow (2009) (215)
- Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. (1990) (213)
- Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit. (1991) (211)
- The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments. (1986) (209)
- Structure of the von Willebrand factor domain interacting with glycoprotein Ib. (1988) (205)
- The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis (2006) (200)
- Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding (2003) (196)
- Elevated platelet count as a cause of abnormal von Willebrand factor multimer distribution in plasma. (1993) (191)
- Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III. (1987) (191)
- Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibalpha mechanoreceptor. (2002) (188)
- Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon. (1988) (182)
- Structure of von Willebrand factor and its function in platelet adhesion and thrombus formation. (2001) (177)
- Mechanisms of Shear-induced Platelet Adhesion and Aggregation (1993) (177)
- Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: implications for pathophysiology and therapy of von Willebrand's disease subtypes. (1982) (176)
- von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia. (1986) (176)
- Transmembrane Calcium Influx Associated with von Willebrand Factor Binding to GP Ib in the Initiation of Shear-Induced Platelet Aggregation (1993) (176)
- Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding. (1990) (174)
- Signaling Through GP Ib-IX-V Activates αIIbβ3 Independently of Other Receptors (2004) (174)
- Modulation of α-Thrombin Function by Distinct Interactions with Platelet Glycoprotein Ibα (2003) (170)
- Laminin stimulates spreading of platelets through integrin α6β1–dependent activation of GPVI (2006) (169)
- Studies on the prolonged bleeding time in von Willebrand's disease. (1976) (168)
- Topography of Ligand-induced Binding Sites, Including a Novel Cation-sensitive Epitope (AP5) at the Amino Terminus, of the Human Integrin Subunit (*) (1995) (168)
- DDAVP enhances platelet adherence and platelet aggregate growth on human artery subendothelium. (1984) (167)
- Activation of platelets in blood perfusing angioplasty-damaged coronary arteries. Flow cytometric detection. (1992) (166)
- Mechanisms of platelet aggregation. (2001) (165)
- Role of 3 Integrins in Melanoma Cell Adhesion to Activated Platelets under Flow (*) (1996) (165)
- Unique Pathway of Thrombin-induced Platelet Aggregation Mediated by Glycoprotein Ib* (2001) (163)
- A heparin-binding domain of human von Willebrand factor. Characterization and localization to a tryptic fragment extending from amino acid residue Val-449 to Lys-728. (1987) (162)
- Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. (2005) (159)
- Proteolysis of von Willebrand Factor and Shear Stress–Induced Platelet Aggregation in Patients With Aortic Valve Stenosis (2000) (156)
- P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. (2011) (154)
- Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation. (1985) (153)
- Isolation of the von Willebrand factor domain interacting with platelet glycoprotein Ib, heparin, and collagen and characterization of its three distinct functional sites. (1989) (146)
- New insights into the mechanisms of platelet adhesion and aggregation. (1994) (145)
- Immunoradiometric Assay of Factor VIII Related Antigen, with Observations in 32 Patients with von Willebrand's Disease (1976) (142)
- Localization and characterization of an alpha-thrombin-binding site on platelet glycoprotein Ib alpha. (1994) (136)
- Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC). (1982) (136)
- Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa. (1993) (130)
- Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin. A model for the regulation of von Willebrand factor binding to platelet glycoprotein Ib. (1991) (129)
- Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome. (1993) (128)
- Old concepts and new developments in the study of platelet aggregation. (2000) (123)
- Function of glycoprotein Ib alpha in platelet activation induced by alpha-thrombin. (1991) (123)
- Acquired von Willebrand's disease in the myeloproliferative syndrome. (1984) (122)
- Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. (2012) (121)
- Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca. (1991) (119)
- Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow. (1999) (119)
- The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi. (2013) (118)
- Subunit composition of plasma von Willebrand factor in patients with the myeloproliferative syndrome. (1986) (116)
- Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites. (1990) (114)
- Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. (1987) (114)
- Identification of Three Tyrosine Residues of Glycoprotein Ib with Distinct Roles in von Willebrand Factor and -Thrombin Binding (*) (1995) (114)
- Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage. (2009) (114)
- Luminographic Detection of von Willebrand Factor Multimers in Agarose Gels and on Nitrocellulose Membranes (1990) (112)
- Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. (2004) (111)
- Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus (2008) (110)
- Multimeric structure of platelet factor VIII/von Willebrand factor: the presence of larger multimers and their reassociation with thrombin-stimulated platelets. (1982) (110)
- Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor binding. (1991) (108)
- Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly- Asp-dependent mechanism (1989) (107)
- Interaction of purified type IIB von Willebrand factor with the platelet membrane glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and initiates aggregation. (1985) (105)
- Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab (1998) (105)
- Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets. (1986) (104)
- Enhanced shear-induced platelet aggregation in acute myocardial infarction. (1999) (102)
- Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling. (2006) (101)
- Distinct antithrombotic consequences of platelet glycoprotein Ibα and VI deficiency in a mouse model of arterial thrombosis (2006) (101)
- Nonsense mutation in the glycoprotein Ib alpha coding sequence associated with Bernard-Soulier syndrome. (1990) (99)
- Binding of the snake venom-derived proteins applaggin and echistatin to the arginine-glycine-aspartic acid recognition site(s) on platelet glycoprotein IIb.IIIa complex inhibits receptor function. (1990) (99)
- Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2. (2017) (99)
- Homozygous and heterozygous deletions of the von Willebrand factor gene in patients and carriers of severe von Willebrand disease. (1988) (98)
- Isolation and characterization of a collagen binding domain in human von Willebrand factor. (1986) (98)
- HBV pathogenesis in animal models: recent advances on the role of platelets. (2007) (98)
- The platelet glycoprotein Ib-IX complex. (1991) (98)
- Platelet Mimetic Particles for Targeting Thrombi in Flowing Blood (2012) (97)
- Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody. (1985) (96)
- A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ibalpha for the diagnosis of patients with low von Willebrand factor levels. (2004) (95)
- Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease. (1996) (95)
- Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. (2006) (95)
- High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. (2011) (94)
- von Willebrand factor (1993) (93)
- Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ib alpha involved in platelet transfusion refractoriness. (1992) (92)
- Von Willebrand factor: Looking back and looking forward (2007) (92)
- Asymptomatic liver disease in haemophiliacs. (1975) (92)
- Different effects of various anti‐GPIIb‐IIIa agents on shear‐induced platelet activation and expression of procoagulant activity (2003) (91)
- Acquired von Willebrand's disease in the myeloproliferative syndrome. (1985) (91)
- Expression and characterization of von Willebrand factor dimerization defects in different types of von Willebrand disease. (2001) (89)
- Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. (1998) (87)
- von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease. (1983) (86)
- Conformational Changes in the A1 Domain of von Willebrand Factor Modulating the Interaction with Platelet Glycoprotein Ib (*) (1996) (86)
- Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. (2015) (86)
- The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies. (2011) (85)
- Induction of platelet thrombi by bacteria and antibodies. (2002) (85)
- Reversible activation defect of the platelet glycoprotein IIb-IIIa complex in patients with uremia. (1993) (85)
- Functional modulation of the isolated glycoprotein Ib binding domain of von Willebrand factor expressed in Escherichia coli. (1991) (85)
- Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension (2017) (84)
- Lateral Clustering of Platelet GP Ib-IX Complexes Leads to Up-regulation of the Adhesive Function of Integrin αIIbβ3 * (2002) (82)
- Molecular Imaging of Inflammation and Platelet Adhesion in Advanced Atherosclerosis Effects of Antioxidant Therapy With NADPH Oxidase Inhibition (2013) (81)
- von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure. (1993) (81)
- Regulation of von Willebrand Factor Binding to the Platelet Glycoprotein Ib-IX by a Membrane Skeleton-dependent Inside-out Signal* (2001) (80)
- Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin. (1987) (80)
- Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. (2003) (80)
- Distinct biological consequences of integrin alpha v beta 3-mediated melanoma cell adhesion to fibrinogen and its plasmic fragments. (1992) (80)
- Isolation and functional characterization of the von Willebrand factor-binding domain located between residues His1-Arg293 of the alpha-chain of glycoprotein Ib. (1988) (78)
- Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradation. (1984) (77)
- Size regulation of von Willebrand factor-mediated platelet thrombi by ADAMTS13 in flowing blood. (2006) (75)
- Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant. (2009) (75)
- The Role of Platelet Adhesion Receptor GPIb α Far Exceeds That of Its Main Ligand von Willebrand Factor in Arterial Thrombosis. (2006) (75)
- Von Willebrand factor (2003) (75)
- Factor VIII-related properties in platelets from patients with von Willebrand's disease. (1978) (74)
- Factor XI Interacts with the Leucine-rich Repeats of Glycoprotein Ibα on the Activated Platelet* (2004) (73)
- In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura (2006) (71)
- Leptin Enhances the Potency of Circulating Angiogenic Cells Via Src Kinase and Integrin &agr;v&bgr;5: Implications for Angiogenesis in Human Obesity (2010) (71)
- Precipitating antibodies to factor VIII/von Willebrand factor in von Willebrand's disease: effects on replacement therapy. (1981) (71)
- Von Willebrand's disease. (1976) (70)
- Increased thrombogenesis and embolus formation in mice lacking glycoprotein V. (2001) (70)
- Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746. (1988) (69)
- Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow. (2004) (69)
- von Willebrand factor conformation and adhesive function is modulated by an internalized water molecule (2000) (69)
- Characterization of the Initial α-Thrombin Interaction with Glycoprotein Ibα in Relation to Platelet Activation* (1998) (66)
- Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptor. (1991) (65)
- New perspectives on von Willebrand factor functions in hemostasis and thrombosis. (2005) (64)
- Variant Bernard-Soulier syndrome type bolzano. A congenital bleeding disorder due to a structural and functional abnormality of the platelet glycoprotein Ib-IX complex. (1990) (64)
- Distinct Structural Attributes Regulating von Willebrand Factor A1 Domain Interaction with Platelet Glycoprotein Ibα under Flow* (1999) (64)
- Factor VIII antigen in the vessel walls in von Willebrand's disease and haemophilia A. (2009) (63)
- High-resolution analysis of von Willebrand factor multimeric composition defines a new variant of type I von Willebrand disease with aberrant structure but presence of all size multimers (type IC). (1985) (62)
- Type IIB von Willebrand's disease: differential clearance of endogenous versus transfused large multimer von willebrand factor. (1982) (62)
- A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3. (1992) (62)
- Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants. (1993) (61)
- Affinity modulation of the allbl33 integrin (platelet GPIlb-lila) is an intrinsic property of the receptor* (61)
- Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4 (2015) (59)
- Proteolysis of von Willebrand factor in therapeutic plasma concentrates. (1994) (59)
- Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. (2016) (58)
- Antiplatelet Drug Therapy Moderates Immune-Mediated Liver Disease and Inhibits Viral Clearance in Mice Infected with a Replication-Deficient Adenovirus (2007) (57)
- Bernard‐Soulier syndrome: quantitative characterization of megakaryocytes and platelets by flow cytometric and platelet kinetic measurements (1994) (57)
- Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis (2018) (57)
- Type IIB Tampa: a variant of von Willebrand disease with chronic thrombocytopenia, circulating platelet aggregates, and spontaneous platelet aggregation (1985) (57)
- Type I interferon is a therapeutic target for virus-induced lethal vascular damage (2014) (55)
- ADAP is required for normal αIIbβ3 activation by VWF/GP Ib-IX-V and other agonists (2007) (55)
- The Activation State of the Integrin Affects Outside-in Signals Leading to Cell Spreading and Focal Adhesion Kinase Phosphorylation (*) (1995) (55)
- Platelets Mediate Cytotoxic T Lymphocyte-Induced Liver Damage. (2005) (54)
- Crystal structure of the von Willebrand factor modulator botrocetin. (2001) (54)
- von Willebrand factor. (2003) (54)
- Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation. (2016) (54)
- Role of von Willebrand factor in platelet thrombus formation. (2000) (52)
- Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex. (2017) (52)
- Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib. (2019) (51)
- Interaction of Integrin αIIbβ3 with Multiple Fibrinogen Domains during Platelet Adhesion * (1995) (51)
- A molecular approach to the classification of von Willebrand disease. (2001) (51)
- Structure and function of von Willebrand factor: relationship to von Willebrand's disease. (1991) (51)
- The von willebrand factor domain-mediating botrocetin-induced binding to glycoprotein IB lies between Val449 and Lys728. (1987) (50)
- The heterogeneity of type IIA von Willebrand's disease: studies with protease inhibitors. (1986) (50)
- The Structure and Function of von Willebrand Factor (1992) (50)
- A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis (2017) (50)
- Platelets and von Willebrand disease. (1985) (50)
- Heparin-associated thrombocytopenia: observations on the mechanism of platelet aggregation. (1989) (49)
- Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin. Role of platelet activation, fibrinogen, and two distinct membrane receptors. (1987) (49)
- Precipitating antibodies in von Willebrand's disease (1976) (49)
- Molecular Imaging of Platelet–Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis (2015) (49)
- Interaction of von Willebrand factor with platelets and the vessel wall (2015) (49)
- Expression of human platelet glycoprotein Ib alpha in transgenic mice. (1993) (48)
- GPIbα is required for platelet-mediated hepatic thrombopoietin generation. (2018) (48)
- The Role of von Willebrand Factor and Fibrinogen in the Initiation of Platelet Adhesion to Thrombogenic Surfaces (1995) (48)
- Increased Fragmentation of von Willebrand Factor, Due to Abnormal Cleavage of the Subunit, Parallels Disease Activity in Recurrent Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and Discloses Predisposition in Families (1999) (48)
- Comparison of VerifyNow-P2Y12 test and Flow Cytometry for monitoring individual platelet response to clopidogrel. What is the cut-off value for identifying patients who are low responders to clopidogrel therapy? (2009) (48)
- Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. (2002) (48)
- PROTEOLYTIC DEGRADATION OF VON WILLEBRAND FACTOR AFTER DDAVP ADMINISTRATION IN NORMAL INDIVIDUALS (1987) (47)
- Perspectives series: Cell adhesion in vascular biology (1997) (47)
- Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ibalpha in a flow field. (1999) (47)
- Separation of human megakaryocytes by state of differentiation on continuous gradients of Percoll: size and ploidy analysis of cells identified by monoclonal antibody to glycoprotein IIb/IIIa. (1986) (47)
- Neutrophils release brakes of coagulation (2010) (46)
- Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function (2009) (46)
- A Role for von Willebrand Factor Proline Residues 702-704 in Ristocetin-Mediated Binding to Platelet Glycoprotein Ib (1993) (45)
- Type IIB von Willebrand disease: a paradox explains how von Willebrand factor works (2004) (44)
- Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa. (1990) (43)
- A new variant of type II von Willebrand disease with aberrant multimeric structure of plasma but not platelet von Willebrand factor (type IIF). (1986) (43)
- Familial incidence of precipitating antibodies in von Willebrand's disease: a study of four cases. (1979) (42)
- Modeling and Functional Analysis of the Interaction between von Willebrand Factor A1 Domain and Glycoprotein Ibα* (2000) (42)
- Binding of α-thrombin to surface-anchored platelet glycoprotein Ibα sulfotyrosines through a two-site mechanism involving exosite I (2011) (41)
- Unravelling the mechanism and significance of thrombin binding to platelet glycoprotein Ib (2010) (41)
- Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment. (1993) (40)
- Cloning of the murine platelet glycoprotein Ibalpha gene highlighting species-specific platelet adhesion. (1997) (40)
- Molecular Imaging Reveals Rapid Reduction of Endothelial Activation in Early Atherosclerosis With Apocynin Independent of Antioxidative Properties (2013) (39)
- ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. (2007) (39)
- Platelet and von Willebrand factor interactions at the vessel wall (2004) (39)
- Distinct spatio-temporal Ca2+ signaling elicited by integrin alpha2beta1 and glycoprotein VI under flow. (2009) (39)
- A new congenital platelet abnormality characterized by spontaneous platelet aggregation, enhanced von Willebrand factor platelet interaction, and the presence of all von Willebrand factor multimers in plasma. (1989) (39)
- A Type 2b von Willebrand Disease Mutation (lle546→Val) Associated with an Unusual Phenotype (1997) (38)
- Role for ADAP in shear flow-induced platelet mechanotransduction. (2010) (38)
- Disulfide bond requirements for assembly of the platelet glycoprotein Ib-binding domain of von Willebrand factor. (1993) (38)
- Type IIB Tampa: a variant of von Willebrand disease with chronic thrombocytopenia, circulating platelet aggregates, and spontaneous platelet aggregation. (1985) (37)
- von Willebrand disease. (1987) (37)
- Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking (2017) (37)
- von willebrand disease type IIC with different abnormalities of von willebrand factor in the same sibship (1986) (36)
- von Willebrand factor and fibrinogen. (1993) (35)
- Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries. (2018) (34)
- Independent assembly and secretion of a dimeric adhesive domain of von Willebrand factor containing the glycoprotein Ib-binding site. (1991) (34)
- The heterogeneity of type IIA von Willebrand's disease: studies with protease inhibitors (1986) (33)
- The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice. (2008) (33)
- Variable effect of P2Y12 inhibition on platelet thrombus volume in flowing blood (2011) (33)
- Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia (2018) (33)
- Contributions of thrombin targets to tissue factor‐dependent metastasis in hyperthrombotic mice (2014) (32)
- Anti-idiotypic antibodies against an antibody to the platelet glycoprotein (GP) IIb-IIIa complex mimic GP IIb-IIIa by recognizing fibrinogen. (1992) (32)
- Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va. (2016) (32)
- Glycoprotein Ib and von Willebrand Factor in the Process of Thrombus Formation (1994) (31)
- Factor VIII and chronic renal failure. (1977) (31)
- Platelet Aggregation on Extracellular Matrix: Effect of a Recombinant GPIb-Binding Fragment of von Willebrand Factor (1993) (31)
- von Willebrand factor as a target for antithrombotic intervention. (1992) (31)
- Nervous Regulation of Factor‐VIII Levels in Man (1971) (30)
- The effect of DDAVP on plasma levels of von Willebrand antigen II in normal individuals and patients with von Willebrand's disease. (1984) (30)
- CHAPTER 18 – Platelet Thrombus Formation in Flowing Blood (2007) (28)
- Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics (2018) (28)
- Classification of von willebrand disease (1987) (28)
- Chapter 20 – Platelet Thrombus Formation in Flowing Blood (2013) (28)
- The role of the porcine von willebrand factor: baboon platelet interactions in pulmonary xenotransplantation (2002) (28)
- Developing Basic and Clinical Research on von Willebrand Factor and von Willebrand Disease (2000) (27)
- Further characterization of platelet-type von Willebrand's disease in Japan (1984) (26)
- Pathogenesis and classification of von Willebrand disease. (1994) (26)
- Divalent cations regulate the organization of integrins αvβ3 and αvβ5 on the cell surface (1996) (26)
- 14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling. (2018) (25)
- Platelet interactions with vessel wall components during thrombogenesis. (2006) (24)
- Correlation between circulating levels of von Willebrand's antigen II and von Willebrand factor: discrimination between type I and type II von Willebrand's disease. (1984) (24)
- The activation state of the integrin alpha IIb beta 3 affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation. (1995) (23)
- Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis (2014) (23)
- Platelet collagen receptors and risk prediction in stroke and coronary artery disease. (2001) (22)
- Development of factor VIII antibody in haemophilic monozygotic twins. European Study Group of Factor VIII Antibody. (2009) (22)
- Contribution of leptin receptor N-linked glycans to leptin binding. (2008) (22)
- Immunological Heterogeneity of Haemophilia B: a Multicentre Study of 98 Kindreds (1978) (21)
- Evaluation of the Abnormal Platelet Function in von Willebrand Disease by the Blood Filtration Test (1996) (20)
- Increased fragmentation of von Willebrand factor, due to abnormal cleavage of the subunit, parallels disease activity in recurrent hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and discloses predisposition in families. The Italian Registry of Familial and Recurrent HUS/TTP. (1999) (19)
- Evidence that the arg1744 gly1745 asp1746 sequence in the GPIIb-IIIa-binding domain of von Willebrand factor is involved in platelet adhesion and thrombus formation on subendothelium. (1993) (19)
- Altered von Willebrand factor subunit proteolysis and multimer processing associated with the Cys2362Phe mutation in the B2 domain (2006) (19)
- Fine Mapping of Monoclonal Antibody Epitopes on Human von Willebrand Factor Using a Recombinant Peptide Library (1992) (19)
- CONCENTRATES OF CLOTTING-FACTOR IX (1976) (19)
- von Willebrand factor competes with fibrin for occupancy of GPIIb:IIIa on thrombin-stimulated platelets (1990) (19)
- Receptor-specific antiplatelet therapy. (1989) (18)
- von Willebrand's Disease. (1983) (18)
- Mechanisms of anti-GPIbα antibody-induced thrombocytopenia in mice. (2020) (17)
- Optimization of a Recombinant von Willebrand Factor Fragment as an Antagonist of the Platelet Glycoprotein Ib Receptor (1993) (17)
- VON WILLEBRAND FACTOR, NOW CLONED (1986) (16)
- Further characterization of platelet-type von Willebrand's disease in Japan. (1984) (16)
- Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain. (2004) (16)
- Molecular Imaging of VWF (von Willebrand Factor) and Platelet Adhesion in Postischemic Impaired Microvascular Reflow (2018) (15)
- Selective Interaction of a Conformationally-constrained Arg-Gly- Asp (RGD) Motif with the Integrin Receptor αvβ3 Expressed on Human Tumor Cells (1997) (14)
- Conditional Knockout of Integrin α2β1 in Murine Megakaryocytes Leads to Reduced Mean Platelet Volume (2013) (14)
- Interruption of vascular thrombosis by bolus anti-platelet glycoprotein IIb/IIIa monoclonal antibodies in baboons. (1993) (14)
- Unique interactions of asialo von Willebrand factor with platelets in platelet-type von Willebrand disease. (1987) (14)
- Differences Between Heterozygous Dominant and Recessive von Willebrand’s Disease Type I Expressed by Bleeding Symptoms and Combinations of Factor VIII Variables (1983) (13)
- Inhibition of platelet-vessel wall interaction. Platelet receptors, monoclonal antibodies, and synthetic peptides. (1990) (13)
- Isoelectric focusing of human von Willebrand factor in urea-agarose gels (1983) (12)
- Letter: Enhanced factor VIII activity in von Willebrand's disease. (1974) (12)
- von Willebrand factor binding to platelet glycoprotein Ib complex. (1992) (12)
- Assessment of Novel Antioxidant Therapy in Atherosclerosis by Contrast Ultrasound Molecular Imaging (2018) (12)
- CLASSIFICATION OF VARIANT von WILLEBRAND'S DISEASE SUBTYPES BY ANALYSIS OF FUNCTIONAL CHARACTERISTICS AND MULTIMERIC COMPOSITION OF FACTOR VIII/von WILLEBRAND FACTOR * (1981) (11)
- Cell adhesion in vascular biology: series introductin. (1996) (11)
- Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain. (1997) (11)
- PRELIMINARY TRIAL OF CYCLOPHOSPHAMIDE IN THE MANAGEMENT OF HEMOPHILIACS WITH FACTOR VIII INHIBITORS * (1975) (11)
- Enhanced botrocetin‐induced type iib von willebrand factor binding to platelet glycoprotein ib initiates hyperagglutination of normal platelets (1990) (11)
- Humanized GPIbα-von Willebrand factor interaction in the mouse. (2018) (11)
- Isoelectric focusing of human von Willebrand factor in urea-agarose gels. (1983) (11)
- von Willebrand factor competes with fibrin for occupancy of GPIIb:IIIa on thrombin-stimulated platelets. (1990) (10)
- Effect of shear stress on fibrinogen adsorption and its conformational change. (1995) (10)
- Factor VIII/von Willebrand factor in glomerular nephropathies. (1981) (10)
- Endothelial cells: they only look all alike (2001) (10)
- Functional domains of von Willebrand factor involved in interactions with platelets and the subendothelium. (1988) (9)
- Structure and function of the von Willebrand factor A1 domain. (2002) (9)
- Tensile destruction test as an estimation of partial proteolysis in fibrin clots (2002) (9)
- Platelet GPIb: sensing force and responding. (2015) (8)
- Divalent cations regulate the organization of integrins alpha v beta 3 and alpha v beta 5 on the cell surface. (1996) (8)
- Platelet deposition on severely damaged vessel wall at flow conditions typical of stenotic vessel is inhibited by LJ-CP3. (antiplatelet glycoprotein GPIIB/IIIA monoclonal antibody) (1990) (7)
- CHARACTERIZATION OF THE VON WILLEBRAND FACTOR-BINDING DOMAIN OF PLATELET MEMBRANE GLYCOPROTEIN Ib (1987) (7)
- Synthetic peptides inhibit the interaction of von Willebrand factor-platelet membrane glycoproteins (1993) (7)
- Indications for a protective function of beta2‐glycoprotein I in thrombotic thrombocytopenic purpura (2012) (7)
- Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo (2020) (7)
- CLOTTING FACTORS IN VON WILLEBRAND'S DISEASE (1974) (6)
- CIRCULATING ANTICOAGULANTS IN HÆMOPHILIA (1970) (6)
- Spontaneous platelet aggregation in type IIB tampa von willebrand disease is inhibited by the 52/48‐kDa fragment of normal von willebrand factor, which contains the GPIb binding domain (1989) (6)
- [Factor VIII inhibitors]. (1977) (6)
- In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS 13 in thrombotic thrombocytopenic purpura (2018) (6)
- Case report: 1‐deamino‐8‐D‐arginine vasopressin and cryoprecipitate in variant von Willebrand disease (1985) (5)
- Platelet adhesion receptors and their participation in hemostasis and thrombosis. (2001) (5)
- Acquired abnormalities of von Willebrand factor: facts to consider in patients with unexpected bleeding. (1993) (5)
- Complement Component C3 Binds to the A3 Domain of von Willebrand Factor (2018) (5)
- Engineered idiotypes. Immunochemical analysis of antigenized antibodies expressing a conformationally constrained Arg-Gly-Asp motif. (1995) (5)
- Immunoradiometric Assay of Factor VIII Related Antigen (1975) (5)
- Two antipeptide monoclonal antibodies that recognize adhesive sequences in fibrinogen: identification of antigenic determinants and unrelated sequences using synthetic combinatorial libraries. (1995) (4)
- [21] Secretion of von Willebrand factor from platelets (1989) (4)
- Is VITT really a HIT (2021) (4)
- PATHOGENESIS OF VON WILLEBRAND'S DISEASE (1976) (4)
- Platelet function and arterial thrombosis. (2001) (4)
- Progress in vascular biology, hemostasis, and thrombosis (1991) (4)
- Proteolysis of Von Willebrand Factor Influences Inflammatory Endothelial Activation and Vascular Compliance in Atherosclerosis (2020) (4)
- Binding of Erythrocyte ICAM–4 to the Platelet Activated Integrin α IIb β 3 leads to a Direct Erythrocyte-Platelet Adhesion Under Venous Flow Shear Rate (2012) (4)
- Generation and characterization of specific antibodies directed to the binding domain of adhesive molecules. (1988) (4)
- Distinct spatio-temporal Ca 2 (cid:1) signaling elicited by integrin (cid:2) 2 (cid:3) 1 and glycoprotein VI under flow (2009) (4)
- Hemophilia Care in Italy (1976) (4)
- Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions (2017) (3)
- Von Willebrand's disease and the mechanisms of platelet function. (1995) (3)
- Abstract 499: Development of a Novel Antithrombotic Therapy Targeting Platelet GPIbα: Assessment of Anfibatide In Vitro and in Phase I Clinical Trial (2014) (3)
- Varied immunological reactivity of factor VIII from animal plasmas. (1980) (3)
- Urinary excretion of factor VIII after renal transplantation. (1979) (3)
- multimer distribution in plasma Elevated platelet count as a cause of abnormal von Willebrand factor (2011) (3)
- Von Willebrand factor: a matrix protein that tries to be soluble (2003) (3)
- Mechanism of the Prolonged Bleeding Time in yon Willebrand’s Disease (vWd) (1975) (2)
- Diverse Functional Implications of ADAMTS13 Gene Mutations in Patients with TTP and Congenital Deficiency. (2004) (2)
- Selective interaction of a conformationally-constrained Arg-Gly-Asp (RGD) motif with the integrin receptor alphavbeta3 expressed on human tumor cells. (1997) (2)
- Nonsense mutation in the glycoprotein Iba coding sequence associated with Bernard-Soulier syndrome (platelet receptor/thrombosis/bleeding disorder/platelet adhesion/thrombocytopenia) (2016) (2)
- A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure. (2004) (2)
- Tailored antiplatelet therapy in a patient with ITP and clopidogrel resistance (2014) (2)
- Platelets in Thrombotic and Non-thrombotic Disorders: Platelet receptors: von Willebrand factor (2002) (2)
- Heterogeneity in von Willebrand's disease. (1981) (2)
- IDENTIFICATION OF A SECOND COLLAGEN-BINDING DOMAIN IN HUMAN VON WILLEBRAND FACTOR (1987) (2)
- Secretion of von Willebrand factor from platelets. (1989) (2)
- Author Index/Subject Index (2018) (2)
- Increased Ristocetin Induced Binding of Factor VIII to Platelets in Von Willebrand’s Disease (vWd) (1979) (2)
- Urinary excretion of factor-VIII-related antigen and fibrin(ogen) degradation fragments D and E after kidney transplantation. (1979) (2)
- Extracellular tyrosyl‐tRNA synthetase cleaved by plasma proteinases and stored in platelet α‐granules: Potential role in monocyte activation (2020) (2)
- Proceedings: Mechanisms of the prolonged bleeding time in von Willebrand's disease (vWd). (1975) (2)
- Structure-function relationships of platelet glycoprotein Ib as a receptor for von Willebrand factor. (1986) (2)
- Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe (2014) (1)
- Sca-1 As a Marker of Stress-Induced Thrombopoiesis in Mice (2019) (1)
- CHARACTERIZATION OF A 40 kDa FRAGMENT OF VON WILLEBRAND FACTOR THAT CONTAINS THE GLYCOPROTEIN IIb/IIIa-BINDING DOMAIN (1987) (1)
- Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis (2016) (1)
- Letter: Concentrates of clotting-factor IX. (1976) (1)
- Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition (2014) (1)
- Clinico-Pharmacological Studies of Factor VIII Response After DDAVP (1979) (1)
- Factor VIII Related Properties in Platelets of Patients with von Willebrand’s Disease (VWD) (1977) (1)
- Abstract B19: Brain metastasis depends on tumor cell initiated coagulation (2014) (1)
- Platelet glycoprotein V spatio-temporally controls fibrin formation (2023) (1)
- Alterations in fibrinolysis and blood coagulation. (1969) (1)
- Heterogeneity of type IIA von Willebrand Disease: Studies with protease inhibitor (1986) (1)
- Dysfunctional Platelet Aggregation in Patients with Acute Lassa Fever (2017) (1)
- A key role of the fast ATP-gated P2X1cation channel in the thrombosis of small arteriesin vivo (2003) (1)
- P2×7 Signaling Triggers Tissue Factor Activation and Protein Disulfide Isomerase-Dependent Release of TF+ Microparticles In Thrombosis (2010) (1)
- Platelets HaveMoreThanOneBinding Site forvon Willebrand Factor (1983) (1)
- The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse (2022) (1)
- [Multimeric structure of factor VIII/von Willebrand factor released from human platelets by ADP, collagen and thrombin]. (1983) (1)
- Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets (2017) (1)
- Letter: Clotting factors in von Willebrand's disease. (1974) (1)
- Multiple epitope specificity of monoclonal antibodies to a single synthetic peptide: use in the characterization of the GP IIb-IIIa binding domain of von Willebrand factor. (1990) (1)
- Role of platelet adhesion and aggregation in antithrombotic therapy. (1993) (1)
- Formation of procoagulant platelet derived microparticles through platelet GPIb-interaction with von Willebrand factor under high shear stress. (2005) (1)
- Contribution of Intrinsic and Extrinsic Coagulation Pathways to Thrombus Formation in the Mouse Carotid Artery. (2008) (1)
- Modulation of von Willebrand Factor A1 Domain-Mediated Platelet Aggregation/Agglutination by α-Thrombin. (2004) (1)
- Circulating anticoagulants in haemophilia. (1970) (1)
- Correction and Clarification: Identification of a Cleavage Site Directing the Immunochemical Detection of Molecular Abnormalities in Type IIA von Willebrand Factor (1990) (1)
- Role of Platelet Adhesion and Aggregation in Thrombus Formation: Response (1998) (1)
- Elevated Threshold Shear Rate for the Dependence of Glycoprotein Ibα-Mediated Platelet Thrombus Formation onto Immobilized von Willebrand Factor in Mouse Blood. (2004) (1)
- Novel RGD analogs as antithrombotic agents (1991) (1)
- Different Types of von Wiilebrand’s Disease (vWd): A Study of 101 Cases (1975) (1)
- Deamino d arginine vasopressin (DDAVP): effects on factor VIII related properties in von Willebrand's disease (vWd) (1974) (1)
- Functional modulation of the isolated glycoprotein Ib binding domain of von Willebrand factor expressed in Escherichia coli [Erratum to document cited in CA114(23):226555u] (1991) (0)
- fibrinogen and platelet aggregation complex induced by platelet activation. Relationship to the binding of Increased surface expression of the membrane glycoprotein IIb/IIIa (2011) (0)
- Urinary Excretion of Factor VIII Related Antigen after Renal Transplantation (1977) (0)
- P231Molecular and cellular components of human carotid artery plaque related to thrombogenicity (2014) (0)
- Inside-Out Signaling through ADAP Is Required for VWF-GPIb-IX-V Mediated Integrin AIibb3 Activation. (2005) (0)
- Treatment of Congenital Factor VII Deficiency with a New Concentrate (1977) (0)
- Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin (2003) (0)
- Platelet Membrane Glycoproteins (2002) (0)
- Abstract 894: Leptin Potentiates the Angiogenic Properties of Endothelial Progenitor Cells In Vitro and In Vivo (2007) (0)
- THE FUNCTION OF GLYCOPROTEIN IB (2007) (0)
- Target for Antithrombotic Intervention (2005) (0)
- Abstract 5300: Targeting Ongoing Arterial Thrombosis With Platelet-Specific Microparticles (2009) (0)
- elevated shear stress Activation-independent platelet adhesion and aggregation under (2013) (0)
- C0347 Thrombin binding to platelets of young patients with a history of acute myocardial infarction (2012) (0)
- Melanoma cell-platelet interaction is required for melanoma cell arrest under flow (1995) (0)
- The Thrombosis Phenotype of GPVI-Knockout Mice Is Dependent upon Modifier Gene Loci. (2005) (0)
- Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution (2004) (0)
- Thrombus Formation in a Flow Field with Varying Linear Shear Stress (1994) (0)
- A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice (2018) (0)
- 1-Deamino-8-D-arginine vasopressin and cryoprecipitate in variant von Willebrand disease. (1985) (0)
- Cooperative Calcium Signaling Mediated by Glycoprotein (GP) Ib-IX-V, GPVI and Integrin α 2 β 1 during Platelet Adhesion to Collagen under Flow. (2007) (0)
- Distinct Roles of the Extrinsic and the Intrinsic Coagulation Pathways In Different Murine Thrombosis Models (2011) (0)
- Mechanism of α-Thrombin Binding to Platelet Glycoprotein Ibα (2008) (0)
- Letter: Pathogenesis of von Willebrand's disease. (1976) (0)
- Abstract 5884: Efficacy Assessment of Antiplatelet Therapy in Acute Coronary Syndrome by Time-Volume Analysis of Platelet Thrombus Formation (2009) (0)
- Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets (2022) (0)
- TWO-DIMENSIONAL MULTIMERIC ANALYSIS OF PLASMA AND PLATELET VON WILLEBRAND FACTOR (VWF) WITH IDENTIFICATION OF PLATELET VWF FRAGMENTS EXPRESSING A NEO-ANTIGEN (1987) (0)
- Oral Surgery in Hemophilia with Cryoprecipitate Associated with EACA and Conjugated Estrogens (1972) (0)
- Talin is a master regulator of platelet integrin activation in vivo (2008) (0)
- Murine Model of Fetal and Neonatal Alloimmune Thrombocytopenia Mediated by Anti-GPIb α Versus Anti-β3 Integrin Antibodies. (2006) (0)
- Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection (2022) (0)
- GPIbα Is Essential for Platelet Adhesion during Thrombus Formation: Studies with Mutant Mice Deficient in the Extracellular Domain of GPIbα. (2004) (0)
- THE PLATELET AGGREGATING PROPERTIES OF TYPE IIB VON WILLEBRAND FACTOR (vWF): THE ROLE OF PLATELET ACTIVATION, FIBRINOGEN AND TWO DISTINCT MEMBRANE RECEPTORS (1987) (0)
- Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution (2003) (0)
- Effect of New Direct Oral Anticoagulants on Ex Vivo Platelet and Fibrin Thrombus Formation in Blood Flowing Over Fibrillar Type I Collagen (2011) (0)
- PLATELETS AND THROMBOPOIESIS The CXCR 1 / 2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi (2013) (0)
- Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation (2015) (0)
- STIMULUS-DEPENDENT CHANGES IN THE SURFACE EXPRESSION OF GPIIb/IIIa AND FIBRINOGEN RECEPTORS. RELATIONSHIP TO PLATELET AGGREGATION (1987) (0)
- Ddavp-Induced Alterations In The Multimeric Composition Of Factor Viii/Von Willebrand Factor In Normal And Von Willebrand’S Disease Plasma (1981) (0)
- Maternal Immune Response to Fetal Platelet GPIbα Causes More Frequent Miscarriage in An Animal Model: A Potential Explanation for Low Reported Incidence of Fetal and Neonatal Immune Thrombocytopenia Mediated by Anti-GPIbα Antibodies. (2008) (0)
- GPIbα As a Selective Bidirectional Modulator Of α-Thrombin Prothrombotic Functions Influencing Fibrin Deposition and PAR-Dependent Platelet Activation (2013) (0)
- Mechanism and Functional Consequences of Thrombin Binding to Glycoprotein Ib. (2009) (0)
- Antithrombotic activity of a linear conformationally flexible RGD mimic (1993) (0)
- Platelets, Endothelial Cells and von Willebrand Factor (1977) (0)
- Von Willebrand Disease (vWd) Characterized by Increased Ristocetin Aggregation: A Study of Eleven Cases (1975) (0)
- Which of the Collagen Receptors Is Then the Most Relevant With Regard to Risk for Thrombotic Disease ? (2001) (0)
- Nanogel Drug Carriers Presenting Platelet GPIbα Mimic and Enhance Platelet Adhesion (2016) (0)
- Biomechanical Properties of Bonds Mediated by the von Willebrand Factor A1 Domain during Platelet Adhesion under Flow Conditions. (2004) (0)
- Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo (2019) (0)
- Another Look at Thrombin-GPIba Interaction in Solution Phaseα (2005) (0)
- Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection (2019) (0)
- Distinct Functional Conformations of von Willebrand Factor A1 Domain in Support of Platelet-Surface or Platelet-Platelet Interactions. (2007) (0)
- [Further evaluation of GPIb binding domain of vWf by synthetic peptides]. (1992) (0)
- Tu-W26:2 Endothelial cells and the regulation of thrombosis (2006) (0)
- Molecular Properties of Human Platelet Integrin αIIbβ3 (1994) (0)
- Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis (2018) (0)
- HOMOZYGOUS AND HETEROZYGOUS COMPLETE DELETIONS OF THE VON WILLEBRAND FACTOR GENE CODING REGION IN SEVERE VON WILLEBRAND DISEASE AND CARRIERS (1987) (0)
- microparticle formation under high shear stress Mechanism of platelet adhesion to von Willebrand factor and (2012) (0)
- Activation of Platelet Function Through G Protein–Coupled Receptors Platelets As Immune Cells: Bridging Inflammation and Cardiovascular Disease In Vivo Thrombus Formation in Murine Models Clinical Aspects of Platelet Inhibitors and Thrombus Formation Adhesion Mechanisms in Platelet Function (2007) (0)
- Platelets Mediate Clearance of Lymphocytic Choriomeningitis Virus Infection Preventing Lethal Hemorrhage. (2006) (0)
- ADAP is required for normal (cid:1) IIb (cid:2) 3 activation by VWF/GP Ib-IX-V and other agonists (2007) (0)
- A NEW PLATELET DISFUNCTION CHARACTERIZED BY SPONTANEOUS PLATELET AGGREGATION AND ENHANCED von WILLEBRAND FACT0R-PLATELET INTERACTION (1987) (0)
- Perivascular Adipose Tissue and Thrombus Formation: ex-vivo Study on Internal Mammary Artery (2018) (0)
- In Vivo Anti-Thrombotic Potency of Engineered Activated Protein C Variants. (2007) (0)
- Variable Reduction Of Thrombus Formation In The Blood Of Patients Treated With Oral Factor Xa and Thrombin Inhibitors: Pathophysiologic and Therapeutic Implications (2013) (0)
- Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis (2016) (0)
- Platelet Aggregation and Fibrin Deposition: The Yin and Yang of Thrombin Activity Regulation By Platelet Glycoprotein Ibα (2014) (0)
- PLATELETS AND THROMBOPOIESIS Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation (2016) (0)
- Abstract 5885: Biomechanical Properties of the Glycoprotein Ib-von Willebrand Factor Interaction Under Flow (2009) (0)
- Apolipoprotein A-IV is an Endogenous Protective Factor for Atherothrombosis (2018) (0)
- Peptides that inhibit von Willebrand Factor binding to the platelet SPIB receptor (1994) (0)
- Nucleotide Polymorphisms in the (cid:97) 2 Gene Define Multiple Alleles That Are Associated With Differences in Platelet (cid:97) 2 (cid:98) 1 Density (1998) (0)
- Abstract 148: Cardiac Myosin Promotes Thrombin Generation and Attenuates Tissue Plasminogen Activator-induced Plasma Clot Lysis (2018) (0)
- Factor VIII/Von Willebrand factor (2015) (0)
- von Willebrand Factor: A Prima Ballerina on Two Different Stages P.M. Mannucci New Perspectives on von Willebrand Factor Functions in Hemostasis and Thrombosis (2005) (0)
- Abstract 58: Delayed Atherosclerosis in a Mouse Model of Bernard-Soulier Syndrome is Independent of Glycoprotein Ibα Extracytoplasmic Domain Deficiency (2014) (0)
- Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor. (2012) (0)
- [Factor VIII and glomerular nephropathy]. (1981) (0)
- glycoprotein IB lies between Val449 and Lys728 The von willebrand factor domain-mediating botrocetin-induced binding to (2013) (0)
- Significance of Abnormal Liver Function Tests in Hemophiliacs: A Follow-Up Study (1977) (0)
- Factor VIII/Von Willibrand Factor Is An Integral Component Of The Platelet Surface (1981) (0)
- Peptides that inhibit binding of von Willebrand factor. (1987) (0)
- The Crystal Structure of α-Thrombin in Complex with Platelet Glycoprotein (GP) Ibα (2004) (0)
- Regulation of High Shear Rate Induced von Willebrand Factor Mediated Platelet Thrombi by ADAMTS-13 . (2004) (0)
- Current Therapy of von Willebrand’s Disease (1994) (0)
- A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release (2014) (0)
- Factor-VIII/von Willebrand factor (2018) (0)
- Abstract 70: P2X7-Induced Thiol-Disulfide Exchange is Critical for the Coupling of Coagulation and Inflammation. (2013) (0)
- Structural and Functional Evidence on the Role of Sulfated Tyrosine Residues In Glycoprotein Ib Binding to α-Thrombin Exosites (2010) (0)
- The Role of Botrocetin on von Willebrand Factor Binding to Glycoprotein Ib (1991) (0)
- Untitled (2018) (0)
- Quiescent platelets circulate in the blood-Flow dynamics and haemostasis (0)
- CRYSTAL STRUCTURE OF BOTROCETIN (2001) (0)
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