Zbyszek Darzynkiewicz | Academic Influence

Zbyszek Darzynkiewicz's AcademicInfluence.com Rankings

Zbyszek Darzynkiewicz

Computer Science

#2329

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#2427

Historical Rank

Data Science

#9

World Rank

#9

Historical Rank

Computational Linguistics

#35

World Rank

#35

Historical Rank

Machine Learning

#154

World Rank

#155

Historical Rank

computer-science Degrees

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Computer Science

Zbyszek Darzynkiewicz's Degrees

PhD Computer Science University of Warsaw
Masters Computer Science University of Warsaw
Bachelors Computer Science University of Warsaw

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Why Is Zbyszek Darzynkiewicz Influential?

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According to Wikipedia, Zbigniew Darzynkiewicz was a Polish-American cell biologist active in cancer research and in developing new methods in histochemistry for flow cytometry. Early life and education From 1945 to 1949, Darzynkiewicz attended a primary school in Dzierżoniów, Poland. He spent his high school years in Skarżysko-Kamienna, Poland. His application to the University of Warsaw's Department of Physics was denied by the communist Social Justice Committee, who viewed him as a "enemy of the people." However, following the intervention of Regina Uszyńska, his high school principal, Darzynkiewicz was permitted to submit an application to the Medical University of Warsaw in the fall of 1953.

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Zbyszek Darzynkiewicz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Features of apoptotic cells measured by flow cytometry. (1992) (2006)
Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). (1997) (1156)
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. (1993) (1073)
Relation of mammalian sperm chromatin heterogeneity to fertility. (1980) (819)
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. (1994) (677)
Current Protocols In Cytometry (1997) (592)
Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells. (1993) (477)
Analysis of cell cycle by flow cytometry. (2004) (464)
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. (1993) (432)
Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. (1977) (409)
Assays of cell viability: discrimination of cells dying by apoptosis. (1994) (389)
Lymphocyte stimulation: a rapid multiparameter analysis. (1976) (367)
Cell cycle dependent expression and stability of the nuclear protein detected by Ki‐67 antibody in HL‐60 cells (1992) (365)
Apoptosis and beyond: cytometry in studies of programmed cell death. (2011) (363)
Apoptosis in adult retinal ganglion cells after axotomy. (1994) (347)
New cell cycle compartments identified by multiparameter flow cytometry. (1980) (323)
Laser-scanning cytometry: A new instrumentation with many applications. (1999) (318)
Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. (1993) (312)
Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells (1989) (307)
Cell cycle-specific effects of lovastatin. (1991) (306)
Discrimination of human leukemia subtypes by flow cytometric analysis of cellular DNA and RNA. (1980) (287)
Analysis of apoptosis by laser scanning cytometry. (1999) (285)
Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2. (1999) (277)
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. (2000) (269)
Accessibility of DNA in situ to various fluorochromes: relationship to chromatin changes during erythroid differentiation of Friend leukemia cells. (1984) (261)
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis. (1998) (255)
Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete “sub‐G1” peaks on DNA content histograms (2007) (253)
Thermal denaturation of DNA in situ as studied by acridine orange staining and automated cytofluorometry. (1975) (251)
DNA strand breaks occurring during apoptosis - their early insitu detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. (1992) (249)
Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. (1994) (239)
Simultaneous measurement by flow cytometry of sperm cell viability and mitochondrial membrane potential related to cell motility. (1982) (234)
Flow cytometry in analysis of cell cycle and apoptosis. (2001) (233)
Interaction of rhodamine 123 with living cells studied by flow cytometry. (1982) (230)
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis. (2000) (225)
Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. (2004) (221)
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. (2002) (219)
Cytometry of cyclin proteins. (1996) (218)
Analysis of apoptosis by cytometry using TUNEL assay. (2008) (216)
Increased mitochondrial uptake of rhodamine 123 during lymphocyte stimulation. (1981) (212)
Differential staining of DNA and RNA in intact cells and isolated cell nuclei with acridine orange. (1990) (211)
Cell cycle-specific effects of tumor necrosis factor. (1984) (210)
Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise (2011) (209)
Constitutive Histone H2AX Phosphorylation and ATM Activation, the Reporters of DNA Damage by Endogenous Oxidants (2006) (208)
Flow cytometry-based apoptosis detection. (2009) (207)
Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents (2007) (204)
Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross‐linking agent cisplatin (2004) (203)
Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation (1995) (203)
Subcompartments of the G1 phase of cell cycle detected by flow cytometry. (1980) (198)
The S-phase cytotoxicity of camptothecin. (1991) (195)
Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. (1994) (195)
Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. (1995) (192)
Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. (1992) (189)
Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis (2005) (188)
BUBR1 deficiency results in abnormal megakaryopoiesis. (2003) (187)
Conformation of RNA in situ as studied by acridine orange staining and automated cytofluorometry. (1975) (187)
Human epidermal cell cultures: growth and differentiation in the absence of differentiation in the absence of dermal components or medium supplements. (1979) (179)
Changes in accessibility of DNA to various fluorochromes during spermatogenesis. (1986) (178)
Flow cytometry of breast carcinoma: I. Relation of DNA ploidy level to histology and estrogen receptor (1981) (175)
Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. (2007) (165)
Heme Oxygenase-1 Attenuates Glucose-Mediated Cell Growth Arrest and Apoptosis in Human Microvessel Endothelial Cells (2003) (157)
Analysis of cellular DNA content by flow and laser scanning cytometry. (2010) (157)
Correlated measurements of DNA, RNA, and protein in individual cells by flow cytometry. (1985) (155)
Apoptosis in anititumor strategies: Modulation of cell cycle or differentiation (1995) (154)
Activation-induced expression of human programmed death-1 gene in T-lymphocytes. (1997) (153)
Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. (1995) (150)
Correlation between cell cycle duration and RNA content (1979) (147)
Interactions of fluorochrome‐labeled caspase inhibitors with apoptotic cells: A caution in data interpretation (2003) (147)
Cytostatic and Cytotoxic Effects of Pannon (P‐30 Protein), A Novel Anticancer Agent (1988) (145)
Detection of 5-bromodeoxyuridine (BrdUrd) incorporation by monoclonal antibodies: role of the DNA denaturation step. (1985) (143)
DNA Damage Induced by DNA Topoisomerase I- and Topoisomerase II- Inhibitors Detected by Histone H2AXphosphorylation in Relation to the Cell Cycle Phase and Apoptosis (2003) (142)
Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication. (1995) (142)
Cell heterogeneity during the cell cycle (1982) (141)
Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage. (2006) (139)
Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids. (1981) (138)
Cell Cycle Arrest and Apoptosis Induced by Human Polo-Like Kinase 3 Is Mediated through Perturbation of Microtubule Integrity (2002) (136)
Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry. (2001) (135)
Telomere shortening is an in vivo marker of myocyte replication and aging. (2000) (133)
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes. (1992) (133)
Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. (1994) (132)
Histone H2AX Phosphorylation after Cell Irradiation with UV-B: Relationship to Cell Cycle Phase and Induction of Apoptosis (2005) (131)
Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis. (2000) (130)
Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation. (2000) (130)
sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. (2008) (128)
An approach to diagnosis of T-cell lymphoproliferative disorders by flow cytometry. (2002) (125)
Camptothecin, teniposide, or 4'-(9-acridinylamino)-3-methanesulfon-m-anisidide, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S phase of HL-60 cells. (1991) (124)
Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials. (1999) (124)
Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. (1996) (124)
Flow cytofluorimetry: discrimination between single cells and cell aggregates by direct size measurements. (1975) (122)
Two‐chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5 (2000) (122)
ER-Golgi network--a future target for anti-cancer therapy. (2009) (122)
Interactions of antitumor agents Ametantrone and Mitoxantrone (Novatrone) with double-stranded DNA. (1985) (119)
Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. (1994) (118)
Ribonucleases as potential modalities in anticancer therapy. (2009) (115)
Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone. (2008) (114)
Action of dihydroxyanthraquinone on cell cycle progression and survival of a variety of cultured mammalian cells. (1980) (111)
Induction of ATM Activation, Histone H2AX Phosphorylation and Apoptosis by Etoposide: Relation to Cell Cycle Phase (2007) (111)
DNA Content Measurement for DNA Ploidy and Cell Cycle Analysis (1997) (108)
Comparison of methods based on annexin‐V binding, DNA content or TUNEL for evaluating cell death in HL‐60 and adherent MCF‐7 cells (1999) (107)
Cell cycle-related changes in nuclear chromatin of stimulated lymphocytes as measured by flow cytometry. (1977) (106)
Caffeine modulates the effects of DNA-intercalating drugs in vitro: a flow cytometric and spectrophotometric analysis of caffeine interaction with novantrone, doxorubicin, ellipticine, and the doxorubicin analogue AD198. (1991) (106)
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart (2001) (105)
Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53. (2006) (105)
CD4 engagement induces Fas antigen‐dependent apoptosis of T cells in vivo (1994) (104)
Relationship between RNA content and progression of lymphocytes through S phase of cell cycle. (1979) (103)
Diverse effects of camptothecin, an inhibitor of topoisomerase I, on the cell cycle of lymphocytic (L1210, MOLT-4) and myelogenous (HL-60, KG1) leukemic cells. (1990) (103)
Flow cytometry of colorectal carcinoma with three-year follow-up (1986) (103)
Luminescence of the solid complexes of acridine orange with RNA. (2005) (102)
Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. (1992) (100)
Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids. (1986) (100)
Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines (2001) (99)
The concentration-dependent diversity of effects of DNA topoisomerase I and II inhibitors on the cell cycle of HL-60 cells. (1991) (98)
The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. (2005) (98)
Determining Cell Cycle Stages by Flow Cytometry (1999) (97)
Different sensitivity of chromatin to acid denaturation in quiescent and cycling cells as revealed by flow cytometry. (1979) (97)
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes. (2008) (97)
Inhibitors of proteases prevent endonucleolysis accompanying apoptotic death of HL-60 leukemic cells and normal thymocytes. (1992) (96)
Activation of nuclear factor kappa B (NF-kappaB) assayed by laser scanning cytometry (LSC). (1998) (96)
Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis. (2002) (94)
Apoptotic cell death during treatment of leukemias. (1994) (93)
Analysis of apoptotic cells by flow and laser scanning cytometry. (2000) (91)
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling (2012) (91)
Measurement of apoptosis. (1998) (91)
Cytometry of the cell cycle: Cycling through history (2004) (90)
Detection of apoptosis-associated DNA strand breaks in fine-needle aspiration biopsies by in situ end labeling of fragmented DNA. (1994) (90)
Handbook of Flow Cytometry Methods (1993) (89)
Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation (1992) (88)
Effect of connective tissue intercellular matrix on lymphocyte stimulation. (1971) (87)
BubR1 is involved in regulation of DNA damage responses (2006) (86)
Cyclotherapy: Protection of Normal Cells and Unshielding of Cancer Cells (2002) (86)
Apoptosis of rat thymocytes triggered by prednisolone, camptothecin, or teniposide is selective to G0 cells and is prevented by inhibitors of proteases. (1992) (86)
Induction of H2AX Phosphorylation in Pulmonary Cells by Tobacco Smoke: A New Assay for Carcinogens (2004) (84)
Cytometry in cell necrobiology revisited. Recent advances and new vistas (2010) (84)
Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs). (2009) (84)
Techniques in Cell Cycle Analysis (1987) (84)
Flow cytometry of breast carcinoma: II. Relation of tumor cell cycle distribution to histology and estrogen receptor (1981) (84)
Effect of n-butyrate on cell cycle progression and in situ chromatin structure of L1210 cells. (1981) (84)
Paclitaxel Induces Primary and Postmitotic G1 Arrest in Human Arterial Smooth Muscle Cells (2004) (84)
Assessment of ATM phosphorylation on Ser‐1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser‐139‐histone H2AX phosphorylation, cell cycle phase, and apoptosis (2005) (83)
ASB-2 Inhibits Growth and Promotes Commitment in Myeloid Leukemia Cells* (2002) (83)
Different patterns of apoptosis of HL‐60 cells induced by cycloheximide and camptothecin (1993) (83)
Induction of apoptosis by 5-azacytidine: drug concentration-dependent differences in cell cycle specificity. (1995) (82)
Bladder cancer diagnosis by flow cytometry. Correlation between cell samples from biopsy and bladder irrigation fluid (1980) (81)
Critical aspects in the analysis of apoptosis and necrosis. (1998) (80)
Chapter 24 Difficulties and pitfalls in analysis of apoptosis (2001) (80)
Exposure of cells to static magnetic field accelerates loss of integrity of plasma membrane during apoptosis. (2002) (79)
Analysis of Cellular DNA Content by Flow Cytometry (2004) (78)
Flow cytometry in bladder cancer detection and evaluation using acridine orange metachromatic nucleic acid staining of irrigation cytology specimens. (1980) (78)
Intercalating agents with covalent bond forming capability. A novel type of potential anticancer agents. 2. Derivatives of chrysophanol and emodin. (1989) (77)
Practical flow cytometry (3rd edn): by Howard M. Shapiro, Wiley-Liss 1995. £49.95 (542 pages) ISBN 0 471 303763 (1995) (76)
Laser scanning cytometry: principles and applications. (2006) (75)
Impaired DNA damage response--an Achilles' heel sensitizing cancer to chemotherapy and radiotherapy. (2009) (75)
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging‐related processes (2007) (74)
Interactions of acridine orange with nucleic acids. Properties of complexes of acridine orange with single stranded ribonucleic acid. (1983) (74)
Cytometry of apoptosis. Historical perspective and new advances. (2012) (74)
Changes in deoxyribonucleoprotein during spermiogenesis in the bull. Sensitivity of DNA to heat denaturation. (1970) (73)
Flow cytometry of low stage bladder tumors: Correlation with cytologic and cystoscopic diagnosis (1982) (73)
Critical Aspects in Analysis of Cellular DNA Content (2010) (72)
2-Deoxy-D-glucose enhances sensitivity of human histiocytic lymphoma U937 cells to apoptosis induced by tumor necrosis factor. (1995) (71)
Simultaneous analysis of cellular RNA and DNA content. (1994) (70)
Nucleoprotein changes and initiation of RNA synthesis in PHA stimulated lymphocytes. (1969) (69)
G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation (1998) (69)
Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function. (2016) (69)
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia. (1997) (68)
Actinomycin binding properties of stimulated human lymphocytes. (1969) (68)
Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage (2006) (68)
Changes in deoxyribonucleo-protein during spermiogenesis in the bull. 3 H-Actinomycin D binding capacity. (1969) (68)
Effects of organic and inorganic selenium compounds on rat mammary tumor cells (1995) (68)
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes (2007) (67)
Polo Box Domain of Plk3 Functions as a Centrosome Localization Signal, Overexpression of Which Causes Mitotic Arrest, Cytokinesis Defects, and Apoptosis* (2006) (67)
Translocation of Bax to mitochondria during apoptosis measured by laser scanning cytometry. (2000) (67)
Changes in cell nuclei during S phase: progressive chromatin condensation and altered expression of the proliferation-associated nuclear proteins Ki-67, cyclin (PCNA), p105, and p34. (1991) (67)
Immunological studies of aging. IX. Impaired proliferation of T lymphocytes detected in elderly humans by flow cytometry. (1984) (67)
Chromatin condensation and sensitivity of DNA in situ to denaturation during cell cycle and apoptosis--a confocal microscopy study. (2001) (67)
Induction of DNA damage response by the supravital probes of nucleic acids (2009) (67)
Expression of G1 and G2 cyclins measured in individual cells by multiparameter flow cytometry: a new tool in the analysis of the cell cycle (1994) (66)
Increased sensitivity of lymphocytes from people over 65 to cell cycle arrest and chromosomal damage. (1983) (65)
Analysis of a cell cycle model based on unequal division of metabolic constituents to daughter cells during cytokinesis. (1984) (65)
Laser scanning cytometry distinguishes lymphocytes, monocytes, and granulocytes by differences in their chromatin structure. (1997) (65)
Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements. (1993) (65)
Difficulties and pitfalls in analysis of apoptosis. (2001) (65)
Ventricular loading is coupled with DNA synthesis in adult cardiac myocytes after acute and chronic myocardial infarction in rats. (1992) (65)
Cytometry of DNA replication and RNA synthesis: Historical perspective and recent advances based on “click chemistry” (2011) (64)
Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species. (2006) (64)
ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis (2006) (63)
Chinese herbal mixture PC SPES in treatment of prostate cancer (review). (2000) (63)
Acid-induced denaturation of DNA in situ as a probe of chromatin structure. (1994) (63)
Condensation of nucleic acids by intercalating aromatic cations. (1984) (62)
Analysis of apoptosis by flow cytometry. (1998) (62)
SYTO probes in the cytometry of tumor cell death (2008) (62)
Flow Cytometry of Apoptosis (2003) (62)
Cytometric methods to detect apoptosis. (2004) (61)
Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry (2015) (61)
During apoptosis of HL-60 and U-937 cells caspases are activated independently of dissipation of mitochondrial electrochemical potential. (2000) (61)
Phosphorylation of p53 on Ser15 during cell cycle and caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation (2008) (60)
Cytotoxic Ribonucleases and RNA Interference (RNAi) (2003) (60)
Direct Inhibition of MmpL3 by Novel Antitubercular Compounds (2019) (59)
Rapid analysis of drug effects on the cell cycle. (1981) (59)
Application of pyronin Y(G) in cytochemistry of nucleic acids. (1987) (58)
Discrimination of cycling and non-cycling lymphocytes by BUdR-suppressed acridine orange fluorescence in a flow cytometric system. (1978) (58)
Constitutive expression of p53 protein in enriched normal human marrow blast cell populations. (1992) (58)
Interactions of acridine orange with double stranded nucleic acids. Spectral and affinity studies. (1987) (58)
Assay of Cell Cycle Kinetics by Multivariate Flow Cytometry Using the Principle of Stathmokinesis (1987) (58)
Effects of extracts of Coriolus versicolor (I'm-Yunity) on cell-cycle progression and expression of interleukins-1 beta,-6, and -8 in promyelocytic HL-60 leukemic cells and mitogenically stimulated and nonstimulated human lymphocytes. (2002) (57)
Upregulation of PD-L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300-mediated NF-κB signaling (2018) (57)
Effect of protease inhibitors on early events of apoptosis. (1996) (56)
The ratio of RNA to total nucleic acid content as a quantitative measure of unbalanced cell growth. (2005) (56)
Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis (2006) (56)
Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry. (2001) (56)
DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry (2009) (56)
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. (1992) (56)
Actinomycin binding of normal and phytohaemagglutinin stimulated lymphocytes. (1969) (55)
Recognition of cells in mitosis by flow cytofluormetry. (1977) (55)
Nuclear chromatin changes during erythroid differentiation of friend virus induced leukemic cells. (1976) (55)
Normal and perturbed Chinese hamster ovary cells: correlation of DNA, RNA, and protein content by flow cytometry (1985) (55)
Human keratinocyte culture. Identification and staging of epidermal cell subpopulations. (1986) (55)
Kinetics of HL-60 cell entry to apoptosis during treatment with TNF-alpha or camptothecin assayed by the stathmo-apoptosis method. (2002) (54)
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells. (1993) (54)
Apoptosis and cell cycle effects induced by extracts of the Chinese herbal preparation PC SPES. (1997) (54)
Berberine suppresses gero-conversion from cell cycle arrest to senescence (2013) (54)
DNA damage signaling, impairment of cell cycle progression, and apoptosis triggered by 5‐ethynyl‐2′‐deoxyuridine incorporated into DNA (2013) (54)
The Schrödinger's cat quandary in cell biology: integration of live cell functional assays with measurements of fixed cells in analysis of apoptosis. (1999) (54)
Specific Proteases of the Rat Mast Cell (1967) (54)
Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1. (1995) (53)
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3 (2012) (53)
Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle. (2004) (53)
Kinetics of the UV‐induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication (2009) (53)
QUANTITATIVE STUDIES ON ENZYMES IN STRUCTURES IN STRIATED MUSCLES BY LABELED INHIBITOR METHODS (1969) (52)
Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin. (1999) (52)
Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells (2011) (52)
ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke (2007) (52)
Differential Staining of DNA and RNA (1997) (51)
High affinity binding of fluorescein isothiocyanate to eosinophils detected by laser scanning cytometry: a potential source of error in analysis of blood samples utilizing fluorescein-conjugated reagents in flow cytometry. (1999) (51)
Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells. (2009) (51)
Comparison of human and mouse sperm chromatin structure by flow cytometry (2004) (51)
Rationale for the real‐time and dynamic cell death assays using propidium iodide (2010) (51)
A comparison of cell cycle-related changes in postmitotic and quiescent AF8 cells as measured by cytofluorometry after acridine orange staining. (1978) (50)
Correlation between DNA replication and expression of cyclins A and B1 in individual MOLT-4 cells. (1997) (50)
RIα influences cellular proliferation in cancer cells by transporting RFC40 into the nucleus (2005) (50)
Potentiation of tumor necrosis factor induced apoptosis by onconase. (1998) (50)
Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase). (2002) (49)
Sequential phosphorylation of Ser‐10 on histone H3 and ser‐139 on histone H2AX and ATM activation during premature chromosome condensation: Relationship to cell‐cycle phase and apoptosis (2006) (49)
Different sensitivity of DNA in situ in interphase and metaphase chromatin to heat denaturation (1977) (48)
NF‐κB inhibitor sesquiterpene parthenolide induces concurrently atypical apoptosis and cell necrosis: Difficulties in identification of dead cells in such cultures (2003) (48)
A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. (2013) (48)
Laser scanning cytometry in pathology of solid tumors. A review. (1997) (48)
Enzyme kinetic reactions and fluorochrome uptake rates measured in individual cells by laser scanning cytometry. (1998) (47)
Cell Cycle Effects and Caspase-Dependent and Independent Death of HL-60 and Jurkat Cells Treated with the Inhibitor of NF-6B Parthenolide (2003) (46)
Enzymatically stable 5' mRNA cap analogs: synthesis and binding studies with human DcpS decapping enzyme. (2006) (46)
DNA damage signaling is activated during cancer progression in human colorectal carcinoma (2010) (46)
Cell concentration and the staining properties of nuclear deoxyribonucleoprotein. (1970) (46)
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes (2014) (46)
Interphase and metaphase chromatin. Different stainability of DNA with acridine orange after treatment at low pH. (1977) (46)
Analysis of DNA Content and BrdU Incorporation (1997) (46)
Phosphorylation of retinoblastoma susceptibility gene protein assayed in individual lymphocytes during their mitogenic stimulation. (1998) (45)
Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling (2011) (45)
Laser scanning cytometry: principles and applications-an update. (2013) (45)
Cytostatic and cytotoxic properties of pyronin Y: relation to mitochondrial localization of the dye and its interaction with RNA. (1986) (45)
DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis (2012) (45)
Dynamic analysis of apoptosis using cyanine SYTO probes: from classical to microfluidic cytometry. (2009) (44)
Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence (2012) (44)
Effect of recombinant tumor necrosis factor on HL‐60 cells: Cell‐cycle specificity and synergism with actinomycin D (1987) (44)
Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes (1995) (44)
Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals. (2006) (44)
Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs. (1994) (43)
Effects of herbal preparation Equiguard on hormone-responsive and hormone-refractory prostate carcinoma cells: mechanistic studies. (2002) (43)
Failure of accumulation of cellular RNA in hamster cells stimulated to synthesize DNA by infection with adenovirus 2. (1980) (43)
Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase (2008) (43)
The Cell Cycle Effects of Camptothecin a (1996) (43)
Simultaneous analysis of DNA replication and apoptosis during treatment of HL-60 cells with camptothecin and hyperthermia and mitogen stimulation of human lymphocytes. (1994) (43)
The cytotoxic ribonuclease onconase targets RNA interference (siRNA) (2008) (43)
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis. (2012) (43)
Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure–function relationship (1999) (43)
Relationship of DNA damage signaling to DNA replication following treatment with DNA topoisomerase inhibitors camptothecin/topotecan, mitoxantrone, or etoposide (2012) (42)
Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification. (2009) (42)
Number and Location of Acetylcholinesterase Molecules at Motor Endplates of the Mouse (1966) (42)
Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks (2016) (42)
Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation, and the cell cycle. (1994) (42)
Staurosporine blocks cell progression through G1 between the cyclin D and cyclin E restriction points. (1994) (42)
Oxidative stress induces cell cycle-dependent Mre11 recruitment, ATM and Chk2 activation and histone H2AX phosphorylation (2008) (42)
Histone H3 phosphorylation in human monocytes and during HL-60 cell differentiation. (1999) (41)
Real‐time cell viability assays using a new anthracycline derivative DRAQ7® (2013) (41)
New Biomarkers Probing Depth of Cell Senescence Assessed by Laser Scanning Cytometry (2010) (41)
Denaturation of RNA and DNA in situ induced by acridine orange. (1983) (41)
Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry. (2011) (41)
Photosensitizing effects of the tricyclic heteroaromatic cationic dyes pyronin Y and toluidine blue O (tolonium chloride). (1988) (41)
Unscheduled synthesis of DNA during mammalian spermatogenesis in response to UV irradiation. (1973) (41)
Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia (2016) (41)
Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation (2008) (41)
Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-Cysteine (2006) (41)
Cytofluorometric studies on conformation of nucleic acids in situ. I. Restriction of acridine orange binding by chromatin proteins. (1976) (40)
Arachidonate 5 lipoxygenase expression in papillary thyroid carcinoma promotes invasion via MMP‐9 induction (2012) (40)
Arsenic Trioxide Arrests Cells Early in Mitosis Leading to Apoptosis (2002) (40)
Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukemic cells. (1992) (40)
Interactions of pyronin Y(G) with nucleic acids. (1987) (40)
Protective effect of hyaluronate on oxidative DNA damage in WI-38 and A549 cells. (1992) (40)
Threshold expression of cyclin E but not D type cyclins characterizes normal and tumour cells entering S phase (1995) (40)
Radiation-induced DNA synthesis in normal and stimulated human lymphocytes. (1971) (40)
Analysis of Cell Death by Flow Cytometry (1996) (39)
Caffeine reverses the cytotoxic and cell kinetic effects of Novantrone (mitoxantrone) (1991) (39)
Apoptosis of S-phase HL-60 cells induced by DNA topoisomerase inhibitors: detection of DNA strand breaks by flow cytometry using the in situ nick translation assay. (1993) (39)
Fluorochrome-labeled inhibitors of caspases: convenient in vitro and in vivo markers of apoptotic cells for cytometric analysis. (2011) (39)
Induction of DNA damage signaling by oxidative stress in relation to DNA replication as detected using “click chemistry” (2011) (39)
Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines (2008) (39)
Erythroid differentiation of Friend leukemia cells as studied by acridine orange staining and flow cytometry. (1979) (38)
Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging (2017) (38)
Detection of DNA strand breaks by flow and laser scanning cytometry in studies of apoptosis and cell proliferation (DNA replication). (2006) (38)
In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors. (2002) (38)
Changes in deoxyribonucleoprotein during spermiogenesis in the bull: increased (3H)actinomycin D binding to nuclear chromatin of morphologically abnormal spermatozoa. (1971) (38)
Model for intermediate steps in monocytic differentiation: c-myc, c-fms, and ferritin as markers. (1987) (37)
Induction of cell differentiation potentiates apoptosis triggered by prior exposure to DNA-damaging drugs. (1995) (37)
Growth of hen erythrocyte nuclei undergoing reactivation in heterokaryons. (1969) (37)
Phosphorylation of retinoblastoma protein assayed in individual HL-60 cells during their proliferation and differentiation. (1998) (37)
Molecular interactions and cellular changes during the cell cycle. (1983) (37)
The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells. (2007) (37)
Use of flow and laser-scanning cytometry in analysis of cell death. (2001) (37)
Suppression of RNA synthesis in lymphocytes by inhibitors of proteolytic enzymes. (1974) (37)
Use of fluorescently labeled caspase inhibitors as affinity labels to detect activated caspases (2002) (37)
Effect of ionic strength in immunocytochemical detection of the proliferation associated nuclear antigens p120, PCNA, and the protein reacting with Ki-67 antibody. (1992) (36)
DNA segments sensitive to single-strand-specific nucleases are present in chromatin of mitotic cells. (1996) (36)
gammaH2AX: A potential DNA damage response biomarker for assessing toxicological risk of tobacco products. (2009) (36)
Denaturation of nucleic acids induced by intercalating agents. Biochemical and biophysical properties of acridine orange-DNA complexes. (1984) (36)
Biomarkers of cell senescence assessed by imaging cytometry. (2013) (36)
Identification of polymorphonuclear leukocytes in cytologic samples for flow cytometry. (1979) (36)
Cell cycle specificity of apoptosis during treatment of leukaemias (2004) (36)
Selective displacement of nuclear proteins by antitumor drugs having affinity for nucleic acids. (1989) (35)
In search of antiaging modalities: Evaluation of mTOR‐ and ROS/DNA damage‐signaling by cytometry (2014) (35)
Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis (2013) (35)
Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage (2012) (35)
DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes (2010) (35)
Laser scanning cytometry for automation of the micronucleus assay. (2012) (35)
Isolation of chondrocytes from calf cartilage. (1965) (35)
Micronuclei assay by laser scanning cytometry. (2001) (35)
Unscheduled expression of cyclins D1 and D3 in human tumour cell lines (1996) (35)
Thermally-induced changes in chromatin of isolated nuclei and of intact cells as revealed by acridine orange staining. (1974) (34)
Genome integrity, stem cells and hyaluronan (2012) (34)
Detection of Histone H2AX Phosphorylation on Ser‐139 as an Indicator of DNA Damage (DNA Double‐Strand Breaks) (2004) (34)
RNA content in human lymphocyte subpopulations. (1978) (33)
Apoptosis goes on a chip: advances in the microfluidic analysis of programmed cell death. (2011) (33)
Flavopiridol Inversely Affects p21WAF1/CIP1 and p53 and Protects p21-Sensitive Cells from Paclitaxel (2002) (33)
Effects of 9,10-anthracenedione, 1,4-bis[(2-[(2-hydroxyethyl)amino]-ethyl)amino]-diacetate on cell survival and cell cycle progression in cultured mammalian cells. (1979) (33)
Use of flow and laser scanning cytometry to study mechanisms regulating cell cycle and controlling cell death. (2001) (33)
Laser scanning cytometric analysis of cyclin B1 in primary human malignancies. (1997) (33)
The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine. (2002) (32)
Interactions of chlorophyllin with acridine orange, quinacrine mustard and doxorubicin analyzed by light absorption and fluorescence spectroscopy. (2003) (32)
Cytology automation by flow cytometry. (1977) (32)
Analysis of Cellular DNA Content by Flow Cytometry (2017) (32)
Relative abundance and patterns of correlation among six cytokines in pleural fluid measured by cytometric bead array. (2003) (32)
Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1γ1 and PP1α, respectively (2005) (31)
MODIFICATION OF THE GELATIN SUBSTRATE PROCEDURE FOR DEMONSTRATION OF ACROSOMAL PROTEOLYTIC ACTIVITY (1972) (31)
Fenretinide-induced caspase 3 activity involves increased protein stability in a mechanism distinct from reactive oxygen species elevation. (2000) (31)
Nucleic acid content and cell cycle distribution of five human bladder cell lines analysed by flow cytofluorometry (1977) (31)
The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression (2014) (31)
Effects of resveratrol on the G0-G1 transition and cell cycle progression of mitogenically stimulated human lymphocytes (2002) (31)
Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry. (1995) (31)
Laser scanning cytometer (LSC) analysis of fraction of labelled mitoses (FLM) (1996) (31)
Cell death goes LIVE: Technological advances in real-time tracking of cell death (2010) (31)
Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor. (2002) (31)
Cell cycle effects and induction of apoptosis caused by infection of HL-60 cells with human granulocytic ehrlichiosis pathogen measured by flow and laser scanning cytometry. (1998) (31)
Evaluation of in vivo induction of apoptosis in patients with acute leukemia treated on a phase I study of paclitaxel. (1995) (31)
Flow cytometry of lung carcinoma: a comparison of DNA stemline and cell cycle distribution with histology. (1982) (31)
Rise of the micromachines: microfluidics and the future of cytometry. (2011) (31)
DNA stainability in aneuploid breast tumors: comparison of four DNA fluorochromes differing in binding properties. (1992) (30)
Effect of Phytohaemagglutinin on Synthesis of ‘Rapidly-labelled’ Ribonucleic Acid in Human Lymphocytes (1965) (30)
Nucleic Acid Analysis (2004) (30)
Denaturation and condensation of DNA in situ induced by acridine orange in relation to chromatin changes during growth and differentiation of Friend erythroleukemia cells. (1985) (30)
Phosphorylation of Histone H2AX on Ser 139 and Activation of ATM During Oxidative Burst in Phorbol Ester-Treated Human Leukocytes (2006) (30)
Increased accessibility of bases in DNA upon binding of acridine orange. (1983) (30)
Multiparameter detection of apoptosis using red‐excitable SYTO probes (2008) (30)
Onconase, an anti-tumor ribonuclease suppresses intracellular oxidative stress. (2007) (30)
Application of biotin, digoxigenin or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry. (1995) (30)
In situ factors affecting stability of the DNA helix in interphase nuclei and metaphase chromosomes. (1987) (30)
In vitro model of “wound healing” analyzed by laser scanning cytometry: Accelerated healing of epithelial cell monolayers in the presence of hyaluronate (2003) (30)
2-Deoxy-D-glucose Reduces the Level of Constitutive Activation of ATM and Phosphorylation of Histone H2AX (2006) (30)
Cell cycle-related expression of p120 nucleolar antigen in normal human lymphocytes and in cells of HL-60 and MOLT-4 leukemic lines: effects of methotrexate, camptothecin, and teniposide. (1992) (29)
Purine nucleotides modulate proliferation of brown fat preadipocytes (1999) (29)
Cellular RNA content, a feature correlated with cell kinetics and tumor prognosis. (1988) (29)
Detection of in situ activation of transglutaminase during apoptosis: correlation with the cell cycle phase by multiparameter flow and laser scanning cytometry. (2002) (29)
Cytofluorometric studies on conformation of nucleic acids in situ. II. Denaturation of deoxyribonucleic acid. (1976) (29)
Specific Proteases of the Rat Mast Cell: Intracellular Localization of Specific Proteases in Rat Mast Cells (1967) (29)
DEVDase detection in intact apoptotic cells using the cell permeant fluorogenic substrate, (z-DEVD)2-cresyl violet. (2003) (29)
Unscheduled DNA synthesis in hen erythrocyte nuclei reactivated in heterokaryons. (1972) (29)
Flow cytometry for followup examinations of conservatively treated low stage bladder tumors. (1981) (29)
Autoradiography with Tritiated Methotrexate and the Cellular Distribution of Folate Reductase (1966) (28)
Rhodamine 123 alters the mitochondrial ultrastructure of cultured L1210 cells. (1985) (28)
Serum cytokine concentrations and acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation: concurrent measurement of ten cytokines and their respective ratios using cytometric bead array. (2006) (28)
PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2 (2013) (28)
Nitrogen Oxide-Releasing Aspirin Induces Histone H2AX Phosphorylation, ATM Activation and Apoptosis Preferentially in S-Phase Cells: Involvement of Reactive Oxygen Species (2006) (28)
mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib (2015) (28)
Induction of Apoptosis by Camptothecin and Topotecan (1996) (27)
Effects of ellipticine on cell survival and cell cycle progression in cultured mammalian cells. (1980) (27)
TREATMENT OF MOUSE MUSCULAR DYSTROPHY WITH THE PROTEASE INHIBITOR PEPSTATIN (1978) (27)
Effect of staurosporine on MOLT‐4 cell progression through G2 and on cytokinesis (1994) (27)
Monitoring intravesical bacillus Calmette-Guerin treatment of bladder carcinoma with flow cytometry. (1985) (27)
HEPES-Buffered Media in Lymphocyte Cultures 1 (1971) (27)
Apoptosis of peripheral blood lymphocytes in patients with juvenile idiopathic arthritis (2003) (26)
Stathmo-apoptosis: arresting apoptosis by fluorochrome-labeled inhibitor of caspases. (2001) (26)
Caspase-mediated Cell Death in Hematological Malignancies: Theoretical Considerations, Methods of Assessment, and Clinical Implications (2003) (26)
Rapid multiparameter analysis of cell stimulation in mixed lymphocyte culture reactions. (1977) (26)
Metabolic and Kinetic Compartments of the Cell Cycle Distinguished by Multiparameter Flow Cytometry (1984) (26)
Guidelines for the presentation of flow cytometric data. (2004) (26)
Effects of aclacinomycin on cell survival and cell cycle progression of cultured mammalian cells. (1981) (26)
Detection of caspases activation in situ by fluorochrome-labeled inhibitors of caspases (FLICA). (2002) (26)
Attenuation of the oxidative burst-induced DNA damage in human leukocytes by hyaluronan. (2009) (25)
Acid-induced denaturation of DNA in situ as a probe of chromatin structure. (1990) (25)
DNA synthesis and cell division in a mammalian cell mutant temperature sensitive for the processing of ribosomal RNA. (1980) (25)
Col‐F, a fluorescent probe for ex vivo confocal imaging of collagen and elastin in animal tissues (2013) (25)
Dual Functionality of Cyclooxygenase-2 as a Regulator of Tumor Necrosis Factor–Mediated G1 Shortening and Nitric Oxide–Mediated Inhibition of Vascular Smooth Muscle Cell Proliferation (2003) (25)
Immunoseparation and immunodetection of nucleic acids labeled with halogenated nucleotides. (1997) (25)
DNA denaturation in situ. Effect of divalent cations and alcohols (1976) (25)
Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry. (2011) (25)
Induction of differentiation of leukaemic (HL‐60) or prostate cancer (LNCaP, JCA‐1) cells potentiates apoptosis triggered by onconase (2000) (24)
Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor. (2001) (24)
The c‐myc gene regulates the polyamine pathway in DMSO‐induced apoptosis. (1999) (24)
Selective killing of adriamycin-resistant (G2 checkpoint-deficient and MRP1-expressing) cancer cells by docetaxel. (2005) (24)
All that glitters is not gold: All that FLICA binds is not caspase. A caution in data interpretation—and new opportunities (2007) (24)
RNA and DNA content of isolated cell nuclei measured by multiparameter flow cytometry. (1983) (24)
Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin. (2008) (24)
How Diet Intervention via Modulation of DNA Damage Response through MicroRNAs May Have an Effect on Cancer Prevention and Aging, an in Silico Study (2016) (24)
Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB. (2004) (24)
DNA damage detected with γH2AX in endometrioid adenocarcinoma cell lines (2010) (24)
Extent of constitutive histone H2AX phosphorylation on Ser‐139 varies in cells with different TP53 status (2006) (24)
Changes in DNA content of human blood mononuclear cells with senescence. (1982) (23)
The effects of transforming growth factor β3 on the growth of highly enriched hematopoietic progenitor cells derived from normal human bone marrow and peripheral blood (1991) (23)
Unique analytical capabilities of laser scanning cytometry (LSC) that complement flow cytometry. (2001) (23)
Secretion of albumin and alpha-foetoprotein by dimethylsulphoxide-stimulated hepatocellular carcinoma cells. (1983) (23)
Microtransponders, the miniature RFID electronic chips, as platforms for cell growth in cytotoxicity assays (2006) (23)
Detection of 5-bromo-2-deoxyuridine incorporated into DNA by labeling strand breaks induced by photolysis (sbip). (1994) (23)
The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin. (2006) (23)
Multiparameter flow cytometry. Part I: application in analysis of the cell cycle. (1981) (23)
Laser scanning cytometry quantification of estrogen receptors in breast cancer. (1998) (23)
Cytometric detection of chromatin relaxation, an early reporter of DNA damage response (2009) (23)
Differential diagnosis of malignant lymphomas and related disorders by specific pattern of expression of immunophenotypic markers revealed by multiparameter flow cytometry (Review). (2000) (23)
Analysis of Cellular DNA Content by Flow Cytometry (2017) (23)
Real-time cytotoxicity assays. (2011) (23)
Effects of linoleic-Acid on mammary-tumor cell-proliferation are associated with changes in p53 protein expression. (1993) (23)
Characterization of lineage-negative blast subpopulations derived from normal and chronic myelogenous leukemia bone marrows and determination of their responsiveness to human c-kit ligand. (1993) (22)
Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease onconase (Ranpirnase). (2002) (22)
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor. (1998) (22)
Staining with pyronin Y detects changes in conformation of RNA during mitosis and hyperthermia of CHO cells. (1988) (22)
Multiparameter analysis of progeny of individual cells by laser scanning cytometry. (2000) (22)
Novel Assay Utilizing Fluorochrome-Tagged Physostigmine (Ph-F) to In Situ Detect Active Acetylcholinesterase (AChE) Induced during Apoptosis (2005) (22)
Chapter 15 Methods to identify mitotic cells by flow cytometry (2001) (22)
Characterization of bladder papilloma by two-parameter DNA-RNA flow cytometry. (1982) (21)
Four Birds with One Stone: RAPA as Potential Anticancer (2002) (21)
Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells. (2011) (21)
Analysis of apoptosis in solid tumors by laser-scanning cytometry. (1998) (21)
4 – RNA Content and Chromatin Structure in Cycling and Noncycling Cell Populations Studied by Flow Cytometry (1982) (21)
Identification and characterization of endothelial glycoprotein Ib using viper venom proteins modulating cell adhesion. (1999) (21)
Identification of Binding Sites for Efflux Pump Inhibitors of the AcrAB-TolC Component AcrA. (2019) (21)
Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle. (1993) (21)
High frequency of allele-specific down-regulation of HLA class I expression in lung cancer cell lines. (2004) (21)
Effects of inhibition of RNA or protein synthesis on CHO cell cycle progression (1987) (20)
Upregulation of PDL1 Expression by Resveratrol and Piceatannol in Breast and Colorectal Cancer Cells Occurs Via HDAC3/p300-Mediated NFkappaB Signaling (2020) (20)
Unstainable DNA in cell nuclei. Comparison of ten different fluorochromes. (1988) (20)
Effects of the L isomer (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane on cell survival and cell cycle progression of cultured mammalian cells. (1981) (20)
Clinical and laboratory evaluation of all‐trans retinoic acid modulation of chemotherapy in patients with acute myelogenous leukaemia (2000) (20)
Methods to identify mitotic cells by flow cytometry. (2001) (20)
Effect of prednisolone on thymus lymphocytes. 1. Autoradiographic studies on 3 H-actinomycin D binding and 3 H-uridine incorporation. (1971) (20)
Stathmokinetic Analysis of Human Epidermal Cells in vitro (1986) (20)
Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide (2009) (20)
Myocyte DNA synthesis with aging: Correlation with ventricular loading in rats (1993) (20)
NFAT5 Is Protective Against Ischemic Acute Kidney Injury (2014) (20)
Biscoclaurine alkaloid cepharanthine protects DNA in TK6 lymphoblastoid cells from constitutive oxidative damage. (2008) (20)
Do all daughter cells enter the "indeterminate" ("A") state of the cell cycle? Analysis of stathmokinetic experiments on L1210 cells. (1983) (20)
Why Iressa Failed: Toward a Novel Use of Kinase Inhibitors (2003) (19)
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase. (2007) (19)
Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21WAF1, Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells (2014) (19)
Radiation-induced DNA synthesis in nuclei of hen erythrocytes reactivated in heterokaryons. (1971) (19)
Contribution of p 16 INK 4 a and p 21 CIP 1 pathways to induction of premature senescence of human endothelial cells : permissive role of p 53 (2005) (19)
Bivariate analysis of cellular DNA versus RNA content by laser scanning cytometry using the product of signal subtraction (differential fluorescence) as a separate parameter. (2001) (19)
Effects of dihydro-5-azacytidine on cell survival and cell cycle progression of cultured mammalian cells. (1981) (19)
Urinary cytology automation. Preliminary studies with acridine orange stain and flow-through cytofluorometry. (1976) (19)
Effect of prednisolone on thymus lymphocytes. II. Studies on 3 H-actinomycin D Binding and RNA polymerase activity of isolate nuclei. (1971) (19)
Macrophage-mediated cytostasis of neoplastic hemopoietic cells: cytofluorometric analysis of the reversible cell cycle block. (1978) (19)
The interdependence between catalytic activity, Conformational stability and cytotoxicity of onconase (2007) (18)
Flow cytometry of breast carcinoma. III. Possible altered kinetics in axillary lymph node metastases. (1982) (18)
AUTORADIOGRAPHIC METHODS IN ENZYME CYTOCHEMISTRY. I. LOCALISATION OF ACETYLCHOLINESTERASE ACTIVITY USING A 3-H LABELED IRREVERSIBLE INHIBITOR. (1964) (18)
Acridine orange-induced precipitation of mouse testicular sperm cell DNA reveals new patterns of chromatin structure. (1990) (18)
Pro- and Anti-Apoptotic Effects of an Inhibitor of Chymotrypsin-Like Serine Proteases (2004) (18)
Caffeine increases sensitivity of DNA to denaturation in chromatin of L1210 cells (1990) (18)
Detection of cyclins in individual cells by flow and laser scanning cytometry. (1998) (18)
Analysis of human tumors by laser scanning cytometry. (2001) (18)
Cytostatic and Cytotoxic Properties of Amphinase: A Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes (2007) (18)
Induction of apoptosis and cell cycle-specific change in expression of p53 in normal lymphocytes and MOLT-4 leukemic cells by nitrogen mustard. (1995) (18)
Microfluidics: Emerging prospects for anti-cancer drug screening. (2010) (18)
A reversible carnitine palmitoyltransferase (CPT1) inhibitor offsets the proliferation of chronic lymphocytic leukemia cells (2018) (18)
Down-regulation of androgen-receptor and PSA by phytochemicals. (2008) (18)
Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells (2016) (17)
Multiparameter flow cytometric analysis of hepatic nuclear RNA and DNA of normal and hepatotoxin-treated mice. (1984) (17)
Histone H2AX phosphorylation induced by selective photolysis of BrdU‐labeled DNA with UV light: Relation to cell cycle phase (2004) (17)
Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer (2007) (17)
Cytochemical evidence of nucleoprotein changes in rat adrenal cortex following hypophysectomy or dexamethasone suppression. (1972) (17)
DNA damage response as a biomarker in treatment of leukemias (2009) (17)
Effect of swainsonine on stimulation and cell cycle progression of human lymphocytes. (1989) (17)
Another "Janus paradox" of p53: induction of cell senescence versus quiescence (2010) (17)
Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species. (2002) (17)
Monitoring uptake of ellipticine and its fluorescence lifetime in relation to the cell cycle phase by flow cytometry. (1997) (17)
Effects of retinoic acid versus dimethyl sulfoxide on Friend erythroleukemia cell growth. II. Induction of quiescent, nonproliferating cells. (1984) (17)
Spectral properties of fluorochromes used in flow cytometry. (1990) (16)
AUTORADIOGRAPHIC METHODS IN ENZYME CYTOCHEMISTRY. 3. MEASUREMENTS ON ESTERASES IN THE CELLS OF MOUSE KIDNEY. (1964) (16)
Of Cytometry, Stem Cells and Fountain of Youth (2017) (16)
Flow cytometry of apoptosis. (2003) (16)
Combined effects of onconase and IFN-beta on proliferation, macromolecular syntheses and expression of STAT-1 in JCA-1 cancer cells. (2002) (16)
p53 content in relation to cell growth and proliferation in murine L1210 leukemia and normal lymphocytes. (1986) (16)
Morphometry of nucleoli and expression of nucleolin analyzed by laser scanning cytometry in mitogenically stimulated lymphocytes. (2001) (16)
Simple, semiautomatic assay of cytostatic and cytotoxic effects of antitumor drugs by laser scanning cytometry: Effects of the bis‐intercalator WP631 on growth and cell cycle of T‐24 cells (2004) (16)
Detection of DNA polymerase activity in fixed cells. (1973) (16)
Chromium induces chromosomal instability, which is partly due to deregulation of BubR1 and Emi1, two APC/C inhibitors (2011) (15)
Expression of Ca antigen in relation to cell cycle in cultured human tumor cells. (1984) (15)
Detection of DNA strand breaks in apoptotic cells by flow- and image-cytometry. (2011) (15)
Cell-cycle distribution of urothelial tumour cells as measured by flow cytometry. (1979) (15)
Effect of camptothecin on mitogenic stimulation of human lymphocytes: Involvement of DNA topoisomerase I in cell transition from G0 to G1 phase of the cell cycle and in DNA replication (1992) (15)
Simultaneous fluorescent labeling of DNA, RNA, and protein. (1990) (15)
The cell cycle effects and induction of apoptosis by 5‐bromouridine in cultures of human leukaemic MOLT‐4 and HL‐60 cell lines and mitogen‐stimulated normal lymphocytes (1994) (15)
Relation of P-glycoprotein expression with spontaneous in vitro apoptosis in B-cell chronic lymphocytic leukemia. (2004) (15)
Distinct patterns of MCM protein binding in nuclei of S phase and rereplicating SV40‐infected monkey kidney cells (2005) (15)
Cytotoxic activity of the amphibian ribonucleases onconase and r-amphinase on tumor cells from B cell lymphoproliferative disorders. (2014) (15)
Dry Mass of Lymphocytes during Transformation after Stimulation by Phytohaemagglutinin (1967) (15)
Distinction between 5-bromodeoxyuridine labeled and unlabeled mitotic cells by flow cytometry. (1983) (15)
When senescence masquerades as DNA damage: Is DNA replication stress the culprit? (2009) (15)
Detection of Mitotic Cells (2004) (14)
Two forms of human DNA polymerase δ: Who does what and why? (2019) (14)
Why Iressa failed: toward novel use of kinase inhibitors (outlook). (2003) (14)
Condensation of DNA in situ in metaphase chromosomes induced by intercalating ligands and its relationship to chromosome banding. (1988) (14)
Direct evidence that Bcr-Abl tyrosine kinase activity disrupts normal synergistic interactions between Kit ligand and cytokines in primary primitive progenitor cells. (2003) (14)
Cytochemical Probes of Cycling and Quiescent Cells Applicable to Flow Cytometry (1987) (14)
DNA in situ sensitivity to denaturation: a new parameter for flow cytometry of normal human colonic epithelium and colon carcinoma. (1987) (14)
Apoptotic death of lymphocytes upon treatment with 2-chloro-2'-deoxyadenosine (2-CdA). (1994) (14)
Rapid quantification of cell viability and apoptosis in B-cell lymphoma cultures using cyanine SYTO probes. (2011) (14)
Effects of resveratrol on the G(0)-G(1) transition and cell cycle progression of mitogenically stimulated human lymphocytes. (2002) (14)
Effects of 9,10-anthracenedione, 1,4-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-, diacetate on cell morphology and nucleic acids of friend leukemia cells. (1980) (13)
Presence of typical neuronal markers in serially cultured cells from adult human brain (1992) (13)
Phosphorylation of RIα by Cyclin-Dependent Kinase CDK 2/Cyclin E Modulates the Dissociation of the RIα-RFC40 Complex (2006) (13)
Proliferation and apoptosis in solid tumors. Analysis by laser scanning cytometry. (2000) (13)
Chick-erythrocyte nucleus reactivation in heterokaryons: suppression by inhibitors of proteolytic enzymes. (1974) (13)
Enforced Adhesion of Hematopoietic Cells to Culture Dish Induces Endomitosis and Polyploidy (2005) (12)
The protein-kinase-C inhibitor h7 blocks normal human lymphocyte stimulation and induces apoptosis of both normal lymphocytes and leukemia molt-4 cells. (1993) (12)
Detection of Histone H2AX Phosphorylation on Ser‐139 as an Indicator of DNA Damage (2019) (12)
THE NUMBER OF ACETYLCHOLINESTERASE MOLECULES IN THE RAT MEGAKARYOCYTE (1966) (12)
Presence of neuronal proteins in serially cultured cells from autopsy human brain (1994) (12)
Different rates of degradation of the proliferation-associated nuclear and nucleolar antigens during apoptosis of hl-60 cells induced by DNA topoisomerase inhibitors. (1993) (12)
The role of the E‐cadherin complex in gastrointestinal cell differentiation (1999) (12)
Differences in the composition and in the efficiency of red cell production of normal and CML erythroid progenitor populations are highlighted by response to human c-kit ligand. (1993) (12)
Kinetic Viability Assays Using DRAQ7 Probe (2013) (12)
The butler did it: search for killer(s) of Kaposi's sarcoma cells in preparations of human chorionic gonadotropin. (1999) (12)
Bivariate Analysis of DNA Content and Expression of Cyclin Proteins (1998) (12)
Retention of the mitochondrial probe rhodamine 123 in normal lymphocytes and leukemic cells in relation to the cell cycle. (1991) (11)
Effect of derivatives of chrysophanol, a new type of potential antitumor agents of anthraquinone family, on growth and cell cycle of L1210 leukemic cells. (1989) (11)
Binding of anti-Z-DNA antibodies in quiescent and activated lymphocytes: relationship to cell cycle progression and chromatin changes (1985) (11)
Different rates of DNA replication at early versus late S‐phase sections: Multiscale modeling of stochastic events related to DNA content/EdU (5‐ethynyl‐2′deoxyuridine) incorporation distributions (2014) (11)
Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells (2009) (11)
Suppressive effect of protease inhibitors on heterokaryons containing chick erythrocyte nuclei. (1974) (11)
Critical Aspects in Analysis of Cellular DNA Content (2011) (11)
Physical and Functional Interactions between Mitotic Kinases during Polyploidization and Megakaryocytic Differentiation (2004) (11)
Cytometric assessment of DNA damage induced by DNA topoisomerase inhibitors. (2009) (11)
Effects of retinoic acid versus dimethyl sulfoxide on Friend erythroleukemia cell growth. I. Cell proliferation, RNA content, and protein content. (1984) (11)
Re: preclinical and clinical development of cyclin-dependent kinase modulators. (2000) (11)
Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy (2016) (11)
Cultured human keratinocytes: discrimination of different cell cycle compartments based upon measurement of nuclear RNA or total cellular RNA content (1989) (11)
Cycling into future: Mass cytometry for the cell‐cycle analysis (2012) (11)
Autoradiographic study of DNA synthesis by epidermal cells in epidermodysplasia verruciformis. (1968) (10)
Cytometry of cell cycle regulatory proteins. (2003) (10)
Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells (2015) (10)
Studies on the origin of the mucin in mucinosis follicularis. (1969) (10)
Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate (2020) (10)
Chlorophyllin protects cells from the cytostatic and cytotoxic effects of quinacrine mustard but not of nitrogen mustard. (2001) (10)
Analysis of spatial correlations between patterns of DNA damage response and DNA replication in nuclei of cells subjected to replication stress or oxidative damage (2013) (10)
Novel strategies of protecting non-cancer cells during chemotherapy: Are they ready for clinical testing? (2011) (10)
Manipulating ovarian aging: A new frontier in fertility preservation (2011) (10)
Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients (2020) (10)
Synergy of 2-deoxy-d-glucose combined with berberine in inducing the lysosome/autophagy and transglutaminase activation-facilitated apoptosis (2017) (10)
Association of pS2 (TFF1) release with breast tumour proliferative rate: in vitro and in vivo studies (1999) (10)
In vitro cytotoxicity of ranpirnase (onconase) in combination with components of R-CHOP regimen against diffuse large B cell lymphoma (DLBCL) cell line. (2013) (10)
Interaction of human decapping scavenger with 5′ mRNA cap analogues: structural requirements for catalytic activity (2007) (10)
Nucleic acid content and nuclear chromatin structure of human bladder cell culture lines as studied by flow cytofluorometry. (1977) (10)
DNA damage detected with gammaH2AX in endometrioid adenocarcinoma cell lines. (2010) (9)
Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1gamma1 and PP1alpha, respectively. (2005) (9)
Subpopulations of human peripheral blood cells: Analysis of granulocytic progenitor cells by flow cytometry and immunologic surface markers (1979) (9)
Flow cytometry in cytopathology. Overview and perspectives. (1988) (9)
Please do not disturb: Destruction of chromatin structure by supravital nucleic acid probes revealed by a novel assay of DNA‐histone interaction (2008) (9)
Altered Sensitivity of DNA in Situ to Denaturation in Apoptotic Cells a (1993) (9)
Compound 48/80 impairs cytokinesis in murine leukemiccells (1984) (9)
Effects of a new amsacrine derivative, N-5-dimethyl-9-(2-methoxy-4-methylsulfonylamino)phenylamino-4- acridinecarboxamide, on cultured mammalian cells. (1987) (9)
A Novel Function of CRL4Cdt2 (2013) (9)
"Liquidless" cell staining by dye diffusion from gels and analysis by laser scanning cytometry: potential application at microgravity conditions in space. (2001) (9)
Flow cytometry in clinical oncology: cell cycle and DNA ploidy in assessing tumor behavior. (1989) (8)
In vitro effects and clinical evaluation of a human chorionic gonadotrophin preparation in acute leukemia (1998) (8)
BUBR 1-deficiency Results In Abnormal (2003) (8)
Effect of prednisolone on RNA synthesis in human lymphocytes stimulated by phytohaemagglutinin. (1969) (8)
In vivo effects of adriamycin or N-trifluoroacetyladriamycin-14-valerate on a mouse lymphoma. (1983) (8)
Phase II Evaluation of a High-Dose Mitoxantrone Based Induction Regimen in Untreated Adults with Acute Myeloid Leukemia (2000) (8)
Flow cytometric methods for RNA content analysis (1991) (8)
In situ detection of DNA strand breaks in analysis of apoptosis by flow- and laser-scanning cytometry. (2002) (8)
Multiparameter flow cytometry. Part II. application in hematology. (1981) (8)
DNA in situ sensitivity to denaturation in bladder cancer and its correlation with tumor stage. (1990) (8)
DNA Damage Response Resulting from Replication Stress Induced by Synchronization of Cells by Inhibitors of DNA Replication: Analysis by Flow Cytometry. (2017) (8)
Affinity of Dinucleotide Cap Analogues for Human Decapping Scavenger (hDcpS) (2007) (8)
QUANTITATIVE ANALYSIS OF THE ESTERASES IN RAT MEGAKARYOCYTES BY A RADIO-ISOTOPE CYTOCHEMICAL TECHNIQUE (1966) (8)
Use of the cyclin e restriction point to map cell arrest in g(1)-induced by N-butyrate, cycloheximide, staurosporine, lovastatin, mimosine and quercetin. (1994) (8)
Quantum dots use both LUMO and surface trap electrons in photoreduction process (2017) (8)
Autoradiographic studies on the stability of ribonucleic acid in phytohaemagglutinin stimulated lymphocytes. (1969) (7)
Nuclear Gene 33/Mig6 regulates the DNA damage response through an ATM serine/threonine kinase–dependent mechanism (2017) (7)
Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties (2018) (7)
Effect of swainsonine on interleukin-2 alpha chain receptor expression and proliferation of human lymphocytes. (1991) (7)
[Programmed death of cells (apoptosis)]. (1993) (7)
Cell fixation in zinc salt solution is compatible with DNA damage response detection by phospho‐specific antibodies (2011) (7)
NFAT 5 Is Protective Against Ischemic Acute Kidney Injury (7)
Regulation of peripheral blood and synovial fluid lymphocyte apoptosis in juvenile idiopathic arthritis (2004) (7)
Disruption of mutated BRAF signaling modulates thyroid cancer phenotype (2014) (7)
Cell Cycle Analysis by Flow and Laser-Scanning Cytometry (2006) (7)
Lipid‐induced changes in vascular smooth muscle cell membrane fluidity are associated with DNA synthesis (1999) (7)
Cell and Nuclear Growth During G1: Kinetic and Clinical Implications a (1986) (7)
Strategies of Protection of Normal Cells During Chemo- and Radio-Therapy Based on Modulation of Cell Cycle and Apoptotic Pathways (2005) (7)
Multivariate analysis of apoptotic markers versus cell cycle phase in living human cancer cells by microfluidic cytometry (2013) (7)
Fluorochrome-Labeled Inhibitors of Caspases: Expedient In Vitro and In Vivo Markers of Apoptotic Cells for Rapid Cytometric Analysis. (2017) (6)
Regional lymph node reactivity in explanted bladder cancer of mice as measured by flow cytometry. (1979) (6)
Kinetic analysis of IFIT1 and IFIT5 interactions with different native and engineered RNAs and its consequences for designing mRNA-based therapeutics (2019) (6)
RNA and DNA content of isolated nuclei from bladder irrigation specimens as measured by flow cytometry. (1984) (6)
DNA in situ sensitivity to denaturation as a marker of human breast tumors. (1989) (6)
Selective extraction of fragmented DNA from apoptotic cells for analysis by gel electrophoresis and identification of apoptotic cells by flow cytometry. (1999) (6)
Thermal stability of nucleosomes studied in situ by flow cytometry: effect of ionic strength and n-butyrate. (1989) (6)
Expression of Neuronal Proteins in Cells from Normal Adult Rat Brain Propagated in Serial Culture (1994) (6)
Cyclic AMP regulates the expression and nuclear translocation of RFC40 in MCF7 cells. (2006) (6)
Effects of [3H]Udr On the Cell‐Cycle Progression of L1210 Cells (1984) (6)
Recent advances in cytometry (2011) (6)
The effects of transforming growth factor beta 3 on the growth of highly enriched hematopoietic progenitor cells derived from normal human bone marrow and peripheral blood. (1991) (6)
5E, 8Z, 11Z, 14Z-eicosatetraenoic acid, a novel trans isomer of arachidonic acid, causes G1 phase arrest and induces apoptosis of HL-60 cells. (2005) (6)
ATM Activation and H2AX Phosphorylation Induced by Genotoxic Agents Assessed by Flow- and Laser Scanning Cytometry. (2017) (6)
Detergent treatment as an alternative to cell fixation for flow cytometry. (1981) (6)
Differential Staining of DNA and RNA (1997) (6)
Cytokinetic effects of bifunctional antitumor intercalator ditercalinium on Friend erythroleukemia cells. (1987) (6)
Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence (2013) (5)
There's more than one way to skin a cat: Yet another way to assess mitotic index by cytometry (2008) (5)
Attenuation of Replication Stress–Induced Premature Cellular Senescence to Assess Anti‐Aging Modalities (2014) (5)
Redundancy in response to DNA damage (2011) (5)
Cytometry : new developments (2004) (5)
Effect of 0.25 n sodium chloride treatment on DNA denaturation in situ in thymus lymphocytes. (1976) (5)
Biguanides and targeted anti-cancer treatments (2015) (5)
Differential expression of human topoisomerase IIIalpha during the cell cycle progression in HL-60 leukemia cells and human peripheral blood lymphocytes. (2000) (5)
Phosphorylation of RIalpha by cyclin-dependent kinase CDK 2/cyclin E modulates the dissociation of the RIalpha-RFC40 complex. (2006) (5)
Versatility of analytical capabilities of laser scanning cytometry (LSC) (2002) (5)
UV-induced DNA synthesis in Xeroderma pigmentosum nuclei in heterokaryons. (1972) (5)
The first examples of mRNA cap analogs bearing boranophosphate modification. (2008) (5)
Nucleoprotein changes and uridine incorporation in rat thymus lymphocytes. I. Cellular characterization of age-dependent thymus involution. (1972) (5)
Effect of different N7 substitution of dinucleotide cap analogs on the hydrolytic susceptibility towards scavenger decapping enzymes (DcpS). (2015) (5)
Cell cycle synchronizing properties of staurosporine (1996) (5)
Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status. (2009) (4)
Overview of Nucleic Acid Analysis (1997) (4)
Cell-cycle analysis of drug-treated cells. (2001) (4)
MicroRNA-133a-Dependent Inhibition of Proximal Tubule Angiotensinogen by Renal TNF (Tumor Necrosis Factor) (2020) (4)
Cell Cycle Analysis by Flow Cytometry (2014) (4)
RNA content and chromatin structure of CHO cells arrested in metaphase by colcemid. (1985) (4)
Constitutive histone H 2 AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species (4)
UPTAKE OF TRITIUM-LABELED ADENOSINE TRIPHOSPHATE BY THE CYTOPLASM OF FIXED INTERSTITIAL CELLS FROM RAT TESTES (1973) (4)
Nuclear cytometry and chromatin organization (2018) (4)
Proliferation and differentiation of normal and leukemic lymphocytes as analyzed by flow cytometry (1981) (4)
Effects of a prospective antitumor agent, 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane diperchlorate, on cultured mammalian cells. (1984) (4)
Increase in cellular RNA in cells infected with DNA oncogenic viruses. (1980) (4)
Human epidermal cell cultures: Growth and differentiation in the absence of dermal components or medium supplements (2016) (3)
Effects of PC-SPES on proliferation and expression of AR/PSA in androgen-responsive LNCaP cells are independent of estradiol. (2002) (3)
Proliferating cell nuclear antigen in archival surgical specimens of malignant lymphoma and metastatic carcinoma: immunohistochemical and flow cytometric analysis. (1993) (3)
Ex Vivo Cytotoxic Activity of Endoribonucleases, Onconase (ranpirnase) and R-Amphinase, against Acute Myeloblastic Leukemia Cells (2008) (3)
POLYVINYL CHLORIDE PROTECTIVE FILMS IN AUTORADIOGRAPHY (1963) (3)
Flow Cytometric Analysis of Cell Death : A Critical Review (1995) (3)
40 Years of My Venture with CYTOMETRY (2020) (3)
Interactions of antitumor drug ditercalinium with nucleic acids in solutions and in situ. (1988) (3)
Assaying drug-induced apoptosis. (2001) (3)
Running m(o)TOR with the brakes on leads to catastrophe at mitosis (2012) (3)
Effects of prospidine on survival and growth of mammalian cells in culture. (1980) (3)
Concurrent detection of lysosome and tissue transglutaminase activation in relation to cell cycle position during apoptosis induced by different anticancer drugs (2018) (3)
The antitumor intercalating drug ditercalinium binds preferentially to RNA in Friend erythroleukemia cells. (1989) (3)
Cytometry of the cell cycle: In search for perfect methodology for DNA content analysis in tissue specimens (2010) (3)
Cortisol-induced changes in U.V. absorption spectra of isolated nuclei from rat liver and thymus. (1973) (3)
Forever young, slim and fit: Rapamycin to the rescue (2009) (3)
One More Reason to Get Arrested (in G1) (2002) (3)
Release of specific proteins from nuclei of HL-60 and MOLT-4 cells by antitumor drugs having affinity to nucleic acids. (1991) (3)
Detection of DNA strand breakage in the analysis of apoptosis and cell proliferation by flow and laser scanning cytometry. (1999) (2)
Activity of Anti-Tumor Endoribonucleases, Onconase (ranpirnase) and R-Amphinase in Chronic Lymphocytic Leukemia (2008) (2)
Abstracts of Poster Presentations (2001) (2)
Pro- and Anti-Apoptotic Effects of an Inhibitor of Chymotrypsin-Like (2004) (2)
Ellipticine-induced changes in cell growth and nuclear morphology. (1980) (2)
Gene 33 / Mig 6 Inhibits Hexavalent Chromium-Induced DNA Damage and Cell Transformation in Human Lung Epithelial Cells (2018) (2)
Pushing cancer cells to commit suicide: Is 072RB, the new BH3 mimetic, up to the job? (2008) (2)
Attenuation of constitutive ATM activation and H2AX phosphorylation in human leukemic TK6 cells by their exposure to static magnetic field (2009) (2)
Rapamycin, Inhibitor of Mtor Kinase, Sensitizes Leukemia Cells to Fludarabine-Induced Apoptosis, but Protects Survival of Normal Lymphocytes. (2004) (2)
Nuclear Gene 33/Mig6 Regulates the DNA Damage Response Through an ATM-dependent Mechanism (2020) (2)
Heme Oxygenase-1 Attenuates Glucose-Mediated Cell Growth Arrest and Apoptosis in (2003) (2)
Phosphorylation of retinoblastoma protein (pRb) assayed in individual cells by multilaser flow cytometry (1998) (2)
Sensitivity to X‐irradiation in relation to cell size of CHO cells synchronized in early G1 (1987) (2)
Synthesis and properties of boranophosphate mRNA cap analogues (2008) (2)
Nucleoprotein changes and uridine incorporation in rat thymocytes. II. Effect of treatment with anti-thymocyte serum in vitro. (1972) (2)
Analysis of DNA Denaturation (1998) (2)
Differential regulation of NFAT 5 by NKCC 2 isoforms in medullary thick ascending limb 3 ( mTAL ) cells 4 5 (2011) (2)
Lymph node reactivity to experimental bladder tumor in preimmunized animals as measured by two parameter flow cytometry. (1979) (2)
Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies. (2020) (1)
Stimulating effect of phytohaemagglutinin upon "rapidly labelled" ribonucleic acid synthesis in human lymphocytes. (1965) (1)
Altered nucleic acid contents of mononuclear cells in blood of renal allograft recipients. (1988) (1)
Male mice show significant age-induced decline in sperm DNA integrity (2013) (1)
Rapid Detection of DNA Strand Breaks in Apoptotic Cells by Flow- and Image-Cytometry. (2017) (1)
Original Articles Translocation of Bax to Mitochondria During Apoptosis Measured by Laser Scanning Cytometry (2000) (1)
Broken beyond repair: Damaging DNA in glioblastoma cells with radiation and camptothecin (2008) (1)
Disruption of mutated BRAF signaling modulates thyroid cancer phenotype (2014) (1)
Chromatin structure in leukaemia: Classification of subtypes and cell kinetics during induction therapy (1982) (1)
Malignancy: A New Approach to the Analysis of Apoptosis in the Leukemic Subpopulation by Flow Cytometry Using a CD45 Gating Strategy. (1999) (1)
Abstract 734: Synergistic antitumor effect of vemurafenib and metformin in thyroid cancer (2015) (1)
AUTORADIOGRAPHIC DETECTION OF SODIUM 24 IN SINGLE CELLS (1967) (1)
Flow cytometric characterization of proliferation-associated nuclear antigen (p105) during the cell cycle in normal lymphocytes and promyelocytic leukemia cells (HL-60). (1995) (1)
Upregulation of PD ‐ L 1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC 3 / p 300 ‐ mediated NF ‐ κ B signaling (2018) (1)
Guarding genome integrity in stem cells (2010) (1)
Rapid and simple detection of gero-suppressive agents (2015) (1)
DNA Damage Induced by DNA Topoisomerase I- and Topoisomerase II- Inhibitors Detected by Histone H2AX Phosphorylation in Leukemic Cells. (2004) (0)
Gene 33 mediates Cr(VI)‐induced DNA damage response (2015) (0)
Differential roles for ARC in apoptosis (2001) (0)
Abstract LB-336: High-content, high-throughput imaging cytometry for fully automated DNA damage analysis (2011) (0)
Ventricular Loading IsCoupled WithDNA Synthesis inAdultCardiac MyocytesAfterAcute andChronic Myocardial Infarction inRats (1992) (0)
[Mechanism of lymphocyte stimulation]. (1971) (0)
Antitumor Activity of Amphibian Ribonucleases, Onconase and R-Amhinase, on Tumor Cells From B-Cell Lymphoproliferative Disorders (2010) (0)
Patent Number : 45 Date of Patent : 4 , 559 , 309 Dec . 17 , 1985 (2017) (0)
Abstract 708: Androgen receptor activation inhibits papillary thyroid carcinoma cell cycle progression (2015) (0)
Zinc supplementation activates Nfe2l2/ARE‐MT2‐antioxidant pathway in a model of diabetic nephropathy (2016) (0)
Assessment of DNA Susceptibility to Denaturation as a Marker of Chromatin Structure (2019) (0)
Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer (2008) (0)
Quantitative Analysis of Spatial Association between Discrete Events Represented by Small Foci in Multicolor 3 D Confocal Microscopy (2012) (0)
Pilot Study of the Feasibility of Assessing DNA Damage and Apoptosis Induced by Chemotherapy in Children with Acute Leukemias. (2005) (0)
7th annual San Antonio flow cytometry forum (2004) (0)
Declining DNA double strand break repair results in male reproductive aging (2014) (0)
Of Cytometry, Stem Cells and Fountain of Youth (2017) (0)
Chronic Myocardial Infarction in Rats (2005) (0)
Advances in Brief Unscheduled Expression of Cyclin Bl and Cyclin E in Several Leukemic and Solid Tumor Cell Lines 1 (2006) (0)
Abstract 1406: Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling, and induces senescence in papillary thyroid carcinoma cells (2011) (0)
Nucleic Acid Analysis (2010) (0)
Abstract 4356: Methylation and expression of androgen receptor in Papillary Thyroid Cancer (2017) (0)
Effect of penicillin on ribonucleic acid synthesis in lymphocytes of sensitized individuals (1967) (0)
Mediated Inhibition of Vascular Smooth − Shortening and Nitric Oxide 1 Mediated G − Dual Functionality of Cyclooxygenase-2 as a Regulator of Tumor Necrosis Factor (2003) (0)
Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging (2017) (0)
Flow cytometry in service of a pathologist (2007) (0)
Cell cycle analysis of activated mononuclear blood cells of renal allograft recipients. (1987) (0)
Cell Cycle Arrest and Apoptosis of Melanoma Cells by Docosahexaenoic Acid : Association with Decreased pRb Phosphorylation 1 (2000) (0)
Acridine Orange with RNA (1982) (0)
Real-Time Fluorescent Imaging of Apoptosis using Chip-Based Technologies (2011) (0)
Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells (2023) (0)
Reviewer acknowledgment (2006) (0)
Synthesis and biochemical properties of the novel, enzymatically stable mRNA cap analogues with versatile potential applications (2005) (0)
AUTORADIOGRAPHIC STUDIES OF CELLS FROM LYMPH NODES DRAINING THE TISSUE GRAFT AREA. (1965) (0)
Renal miR‐195 mediates TNF‐dependent inhibition of NKCC2 (2020) (0)
Insight from photoluminescence into mechanism of heme and iron-sulfur cluster photoreduction mediated by CdTe quantum dots (2016) (0)
Chick-Erythrocyte Nucleus Reactivation ii by Inhibitors of Proteolytic Enzymes (2016) (0)
Polo Box Domain of Plk 3 Functions as a Centrosome Localization Signal , Overexpression of Which Causes (2006) (0)
Na+‐K+‐2Cl‐ cotransporter type 2 (NKCC2) isoform A regulates NFAT5 in medullary thick ascending limb (mTAL) cells (2011) (0)
Nucleic Acid Analysis (2004) (0)
MS3-4 Use of fluorochrome-labeled inhibitors of caspases and serine (Ser) proteases to detect in situ activation of these enzymes during apoptosis (2002) (0)
Tribute to Nils R. Ringertz (1932-2002): Personal Memories (2002) (0)
Nucleic Acid Analysis (2006) (0)
Nucleic Acid Analysis (2004) (0)
Ciprofloxacin-Induced G2 Arrest and Apoptosis in TK6 Lymphoblastoid Cells Is Not Dependent on Double-Strand Break Formation. (2007) (0)
In Situ Activation of Caspases Revealed by Affinity Labeling Their Enzymatic Sites (2013) (0)
Preface to Fifth Edition (2011) (0)
Heat denaturation of DNA in situ, in unbroken cells, was studied in relation to the cell cycle. DNA in metaphase cells denatured at lower temperatures (8~176 lower) than DNA in interphase cells. Among interphase cells, small differences (2003) (0)
To Cycle or Not to Cycle? The Role of Checkpoints in Maintenance of Genome Integrity and Cancer (2002) (0)
New cell cycle compartments distinguished by multiparameter flow cytometry. (1983) (0)
2-1-2017 microRNA-494 and ATF 3 the Targets of Onconase ( ? ) (2019) (0)
Use of interference microscopy for quantitative estimation of alkaline phosphatase activity in Ehrlich ascites tumour cells. (1965) (0)
Narrowing-Induced Cardiomyopathy in Rats (2005) (0)
Rapid Communication Detection of In Situ Activation of Transglutaminase During Apoptosis: Correlation With the Cell Cycle Phase by Multiparameter Flow and Laser Scanning Cytometry (2002) (0)
New insights into cell cycle and DNA damage response machineries through high‐resolution AMICO quantitative imaging cytometry (2013) (0)
Leukemic Lymphocytes Kinases , on the Cell Cycle and Chromatin Structure of Normal Different Effects of Staurosporine , an Inhibitor of Protein Updated (2006) (0)
Teniposide Leukemic Lines : Effects of Methotrexate , Camptothecin , and Normal Human Lymphocytes and in Cells of HL-60 and MOLT-4 Cell Cycle-related Expression of p 120 Nucleolar Antigen in Updated (2006) (0)
marrow blast cell populations (see comments) Constitutive expression of p53 protein in enriched normal human (2012) (0)
Analysis of nuclear chromatine by flow cytometry (1992) (0)
578 SURFACE MARKERS AND RNA CONTENT OF LEUKEMIC BLASTS IN ACUTE MYELOID LEUKEMIA OF CHILDHOOD AS A MEASURE OF STAGE OF MATURATION (1978) (0)
Simultaneous Measurement of Cytokines in Pleural Fluids using Cytometric Beads Array (2017) (0)
ZIP10 mediates renal MT2 production and attenuates oxidative stress (2017) (0)
Cell apoptosis and necrosis studied by flow cytometry (1992) (0)
cellular DNA and RNA Discrimination of human leukemia subtypes by flow cytometric analysis of (2011) (0)
DNA damage and cell kinetics detected by cytometry : using phosphorylated histone H2AX as a marker of DNA double strand breaks (2007) (0)
Nucleic Acid Analysis (2004) (0)
List of Referees, 2009 (2010) (0)
Studies on the kinetic of alkaline phosphatase reaction in ehrlich ascites tumour cells with the use of interference microscopy (1965) (0)
An Autoradiographic Study of the Developing Parietal Cell Population In Neonatal Pigs (1988) (0)
Nucleic Acid Content and Nuclear Chromatin Structure of Human Bladder Cell Culture Lines as Studied by Flow Cytofluorometry 1 (2006) (0)
Abstract 30: Nuclear Factor of Activated T Cells-5(NFAT5) Plays a Protective Role in Renal Ischemia Reperfusion Injury(IRI) (2013) (0)
Synergism between a novelamphibian oocyte ribonuclease andlovastatin ininducing cytostatic andcytotoxic effects inhumanlungandpancreatic carcinoma celllines (1992) (0)
Editorial (1991) (0)
Abstract 2122: Androgen decreases proliferation of thyroid cancer cells (2014) (0)
Assessing DNA Damage Ex Vivo Induced by Chemotherapy Targeting Topoisomerase Inhibitors in Acute Leukemias. (2006) (0)
Plenary lectures MORPHOLOGY AND MOLECULAR ORGANIZATION OF AMPHOTERICIN B AND ITS COPPER COMPLEX IN MODEL MEMBRANE SYSTEM STUDIED BY BREWSTER ANGLE MICROSCOPY (2016) (0)
Abstract 2654: Resveratrol and piceatannol synergistically induce PDL1 expression (2017) (0)
Effect of magnetic field on cell structure and function (2006) (0)
P-3-255 Analysis of cyclin expression on malignant brain tumo (1997) (0)
Chromatin Changes Accompanying Apoptosis Detected by Flow Cytometry (1993) (0)
Abstract 2841: Continuous androgen receptor stimulation in thyroid cancer cells induces irreversible senescence (2016) (0)
Cell Cycle-related Expression of p120 NucÃ- colar Antigen in Normal Human Lymphocytes and in Cells of HL-60 and MOLT-4 Leukemic Lines: Effects of Methotrexate, Camptothecin, and Teniposide1 (2006) (0)
microRNA-494 and ATF3 the targets of onconase(?) (2016) (0)
A and B1 in Individual MOLT-4 Cells Correlation between DNA Replication and Expression of Cyclins (2013) (0)
NFAT5 attenuates damage in the thick ascending limb (TAL) (2013) (0)
Abstract 5524: Gene 33/Mig6 regulates apoptosis and the DNA damage response through independent mechanisms (2017) (0)
Dinucleotide 5' mRNA cap analogues with modified triphosphate bridge: useful tools to study decapping and translation (2006) (0)
Nucleic Acid Analysis (2008) (0)
ascending limb (mTAL) cells Expression and function of NFAT5 in medullary thick (2016) (0)
WS5-2 Unique analytical capabilities of laser scanning cytometry that complement flow cytometry (2002) (0)
An interview with Dr. Zbigniew Darzynkiewicz on his highly cited paper published in Cell Cycle (2009) (0)
XIth International Conference of the Society for Analytical Cytology (1986) (0)
Abstract 3709: Resistance mechanisms to targeted molecular therapy in thyroid cancer (2014) (0)
Synthesis and properties of phosphorothioate 5' mRNA cap dinucleotides (2005) (0)
Synergy of 2-deoxy-d-glucose combined with berberine in inducing the lysosome/autophagy and transglutaminase activation-facilitated apoptosis (2016) (0)
Interferometric measurement of the alkaline phosphatase activity in epithelial cells from the vagina of mice in the course of the keratinization process. (1965) (0)
High-content DNA damage assay: Simultaneous measurement of H2AX phosphorylation, ATM activation, and DNA content (2007) (0)

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