Ze'ev Ronai
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Ze'ev Ronaibiology Degrees
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Philosophy Biology
Ze'ev Ronai's Degrees
- PhD Biochemistry Weizmann Institute of Science
Why Is Ze'ev Ronai Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ze’ev Ronai is an Israeli-American cancer research scientist and Chief Scientific Advisor at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla. Education Ze’ev Ronai was born in Haifa in 1956. He attended Hugim High School in Haifa, and received his B.S. and Ph.D. from the Hebrew University of Jerusalem.
Ze'ev Ronai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulation of JNK signaling by GSTp (1999) (1073)
- ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. (2001) (782)
- Role of redox potential and reactive oxygen species in stress signaling (1999) (732)
- UPR, autophagy, and mitochondria crosstalk underlies the ER stress response. (2015) (692)
- MEKK1/JNK signaling stabilizes and activates p53. (1998) (528)
- The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults (2002) (435)
- Siah2 Regulates Stability of Prolyl-Hydroxylases, Controls HIF1α Abundance, and Modulates Physiological Responses to Hypoxia (2004) (406)
- JNK targets p53 ubiquitination and degradation in nonstressed cells. (1998) (366)
- Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. (2009) (358)
- Cellular thiols and reactive oxygen species in drug-induced apoptosis. (2001) (347)
- Recruitment of a ROC1–CUL1 Ubiquitin Ligase by Skp1 and HOS to Catalyze the Ubiquitination of IκBα (1999) (341)
- Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. (2004) (313)
- Jun NH2-Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress (2001) (310)
- BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. (2003) (308)
- Comparative Metabolic Flux Profiling of Melanoma Cell Lines (2011) (302)
- ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation (2001) (296)
- SUMO-1 Modification of Mdm2 Prevents Its Self-Ubiquitination and Increases Mdm2 Ability to Ubiquitinate p53 (2000) (292)
- Glutathione S-transferase P1–1 (GSTP1–1) Inhibits c-Jun N-terminal Kinase (JNK1) Signaling through Interaction with the C Terminus* (2001) (287)
- Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. (2000) (282)
- Rewired ERK-JNK signaling pathways in melanoma. (2007) (280)
- Ubiquitin ligases in oncogenic transformation and cancer therapy (2017) (277)
- Cooperation between STAT3 and c-jun suppresses Fas transcription. (2001) (256)
- Mdm2 association with p53 targets its ubiquitination (1998) (256)
- p53-Mdm2--the affair that never ends. (2002) (242)
- UV Irradiation and Heat Shock Mediate JNK Activation via Alternate Pathways (*) (1995) (242)
- Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF‐κB (2004) (223)
- Emerging roles of ATF2 and the dynamic AP1 network in cancer (2010) (223)
- Death receptors and melanoma resistance to apoptosis (2003) (220)
- Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors. (2010) (212)
- Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. (2011) (210)
- Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification. (1991) (202)
- Regulators of mitochondrial dynamics in cancer. (2016) (193)
- Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma (2017) (179)
- Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase. (1996) (177)
- Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. (2001) (176)
- Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells (2012) (167)
- ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. (2005) (166)
- CREB and Its Associated Proteins Act as Survival Factors for Human Melanoma Cells* (1998) (164)
- Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. (2015) (161)
- Stress-activated kinases regulate protein stability (1998) (161)
- Translational homeostasis via the mRNA cap-binding protein, eIF4E. (2012) (160)
- G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents. (1993) (159)
- Receptor for RACK1 Mediates Activation of JNK by Protein Kinase C (2005) (157)
- Wnt/β-Catenin Signaling Induces the Expression and Activity of βTrCP Ubiquitin Ligase Receptor (2000) (154)
- c-Jun NH2-terminal Kinases Target the Ubiquitination of Their Associated Transcription Factors* (1997) (153)
- Small Ubiquitin-related Modifier (SUMO)-specific Proteases (2007) (150)
- K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers--a review. (2000) (147)
- HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IκB and β-catenin (1999) (145)
- ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis (2003) (133)
- The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. (2013) (130)
- p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-κB activity and Fas expression (2000) (130)
- REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase (2009) (130)
- Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. (1999) (129)
- Identification of New JNK Substrate Using ATP Pocket Mutant JNK and a Corresponding ATP Analogue* (2001) (129)
- Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1 (2007) (126)
- Conformation-dependent phosphorylation of p53. (1997) (126)
- FAP-1 Association with Fas (Apo-1) Inhibits Fas Expression on the Cell Surface (2003) (123)
- Stress‐induced decrease in TRAF2 stability is mediated by Siah2 (2002) (121)
- Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells (1997) (121)
- Metabolic rewiring in melanoma (2016) (120)
- The Ubiquitin Ligase Siah2 and the Hypoxia Response (2009) (117)
- GST function in drug and stress response. (1999) (117)
- Functional Specialization in Proline Biosynthesis of Melanoma (2012) (116)
- RACK1 mediates activation of JNK by protein kinase C [corrected]. (2005) (116)
- Environmental factors as regulators and effectors of multistep carcinogenesis. (1999) (115)
- Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. (2003) (115)
- Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses (2007) (114)
- Precision Oncology: The Road Ahead. (2017) (113)
- RACK1 Recruits STAT3 Specifically to Insulin and Insulin-Like Growth Factor 1 Receptors for Activation, Which Is Important for Regulating Anchorage-Independent Growth (2006) (113)
- Stability of the ATF2 Transcription Factor Is Regulated by Phosphorylation and Dephosphorylation* (2000) (112)
- The SCFHOS/β-TRCP-ROC1 E3 Ubiquitin Ligase Utilizes Two Distinct Domains within CUL1 for Substrate Targeting and Ubiquitin Ligation (2000) (112)
- ATF2 – at the crossroad of nuclear and cytosolic functions (2012) (112)
- Glycolytic enzymes as DNA binding proteins. (1993) (108)
- RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization (2003) (107)
- Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma. (1994) (105)
- ATF2: A transcription factor that elicits oncogenic or tumor suppressor activities (2008) (101)
- Regulation of p53 Localization and Activity by Ubc13 (2006) (100)
- The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways (2008) (99)
- Preclinical Studies of Celastrol and Acetyl Isogambogic Acid in Melanoma (2007) (99)
- Emerging roles of E3 ubiquitin ligases in autophagy. (2013) (98)
- Regulation of Fas Expression by STAT3 and c-Jun Is Mediated by Phosphatidylinositol 3-Kinase-AKT Signaling* (2002) (98)
- Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. (2000) (97)
- Distinct pattern of p53 phosphorylation in human tumors (2001) (96)
- Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons (2017) (94)
- Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection (2012) (94)
- Regulation of the Ring Finger E3 Ligase Siah2 by p38 MAPK* (2006) (93)
- ATF2 on the double - activating transcription factor and DNA damage response protein. (2007) (92)
- High frequency of K‐ras mutations in normal appearing lung tissues and sputum of patients with lung cancer (1995) (87)
- Inhibition of Siah ubiquitin ligase function (2009) (86)
- ATF2, a paradigm of the multifaceted regulation of transcription factors in biology and disease (2017) (86)
- Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice (2019) (85)
- TIP49b, a Regulator of Activating Transcription Factor 2 Response to Stress and DNA Damage (2001) (84)
- The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans. (2004) (83)
- Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase (2004) (83)
- Understanding Signaling Cascades in Melanoma † (2008) (83)
- ATF2 confers radiation resistance to human melanoma cells (1998) (82)
- The Mdm-2 Amino Terminus Is Required for Mdm2 Binding and SUMO-1 Conjugation by the E2 SUMO-1 Conjugating Enzyme Ubc9* (2001) (80)
- HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. (1999) (79)
- The state of melanoma: challenges and opportunities (2016) (79)
- Contribution of phosphatidylinositol 3‐kinase to radiation resistance in human melanoma cells (1999) (79)
- Suppressor role of activating transcription factor 2 (ATF2) in skin cancer (2008) (78)
- Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells. (1988) (78)
- Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival (2018) (77)
- Activation of c-Jun-NH2-Kinase by UV Irradiation Is Dependent on p21ras* (1996) (76)
- An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis. (2002) (74)
- p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation. (2000) (74)
- Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis (2009) (74)
- JNK-mediated Phosphorylation of Cdc25C Regulates Cell Cycle Entry and G2/M DNA Damage Checkpoint* (2010) (73)
- A Role for ATF2 in Regulating MITF and Melanoma Development (2010) (73)
- PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria (2012) (70)
- jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells. (1995) (70)
- Opposite Roles of FAP-1 and Dynamin in the Regulation of Fas (CD95) Translocation to the Cell Surface and Susceptibility to Fas Ligand-mediated Apoptosis* (2006) (69)
- Ubiquitin Chains in the Ladder of MAPK Signaling (2005) (68)
- Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2. (2007) (68)
- Effects of organic and inorganic selenium compounds on rat mammary tumor cells (1995) (68)
- Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB* (2001) (67)
- c-Jun-NH2 Kinase (JNK) Contributes to the Regulation of c-Myc Protein Stability* (2004) (66)
- RACK1 Function in Cell Motility and Protein Synthesis. (2013) (66)
- Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth (2020) (66)
- Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control (2011) (66)
- Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma (2015) (65)
- Mdm2: A regulator of cell growth and death. (2003) (65)
- Regulation of TIP60 by ATF2 Modulates ATM Activation* (2008) (64)
- β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors (2013) (64)
- Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity (2004) (62)
- Complexes of p21RAS with JUN N-terminal kinase and JUN proteins. (1995) (62)
- Ubiquitin and SUMO systems in the regulation of mitotic checkpoints. (2006) (61)
- PRMT5 function and targeting in cancer (2020) (61)
- PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity (2020) (61)
- Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity. (2019) (59)
- The ER-Bound RING Finger Protein 5 (RNF5/RMA1) Causes Degenerative Myopathy in Transgenic Mice and Is Deregulated in Inclusion Body Myositis (2008) (58)
- Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. (2006) (58)
- Regulators and Effectors of Siah Ubiquitin Ligases (2013) (58)
- Roquin-2 Promotes Ubiquitin-Mediated Degradation of ASK1 to Regulate Stress Responses (2014) (58)
- SUMO in Cancer - Wrestlers Wanted (2002) (57)
- Interplay between Cdh1 and JNK activity during the cell cycle (2010) (57)
- Degradation of Newly Synthesized Polypeptides by Ribosome-Associated RACK1/c-Jun N-Terminal Kinase/Eukaryotic Elongation Factor 1A2 Complex (2013) (57)
- Ubiquitination and Degradation of ATF2 Are Dimerization Dependent (1999) (57)
- Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation (2015) (55)
- Regulation of 2-Oxoglutarate (α-Ketoglutarate) Dehydrogenase Stability by the RING Finger Ubiquitin Ligase Siah* (2004) (55)
- USP13 Enzyme Regulates Siah2 Ligase Stability and Activity via Noncatalytic Ubiquitin-binding Domains* (2011) (55)
- The LIM domain protein UNC-95 is required for the assembly of muscle attachment structures and is regulated by the RING finger protein RNF-5 in C. elegans (2004) (54)
- Inhibition of Melanoma Growth and Metastasis by ATF2-Derived Peptides (2004) (54)
- Emerging roles of ATF2 and the dynamic AP1 network in cancer (2010) (54)
- Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation (2006) (53)
- Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy. (2012) (53)
- Amino-terminal-derived JNK Fragment Alters Expression and Activity of c-Jun, ATF2, and p53 and Increases H2O2-induced Cell Death* (2000) (53)
- Adaptive Stress Responses During Tumor Metastasis and Dormancy. (2016) (52)
- SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells (2020) (52)
- Mutant K‐ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis (1995) (51)
- Down-regulation of Tumor Necrosis Factor α Expression by Activating Transcription Factor 2 Increases UVC-induced Apoptosis of Late-stage Melanoma Cells* (1999) (51)
- Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer. (2007) (50)
- Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of BrafV600E::Pten−/− melanoma (2013) (49)
- Translational Reprogramming Marks Adaptation to Asparagine Restriction in Cancer (2019) (49)
- The Cytoprotective Aminothiol WR1065 Activates p53 through a Non-genotoxic Signaling Pathway Involving c-Jun N-terminal Kinase* (2003) (49)
- Siah: New Players in the Cellular Response to Hypoxia (2004) (49)
- Melanoma models for the next generation of therapies. (2021) (49)
- Control of p53 multimerization by Ubc13 is JNK-regulated (2009) (46)
- Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment. (2001) (46)
- MEKK 1 / JNK signaling stabilizes and activates p 53 (1998) (45)
- Analysis of JNK, Mdm2 and p14(ARF) contribution to the regulation of mutant p53 stability. (2000) (45)
- Stabilization and Activation of p53 by the Coactivator Protein TAFII31* (2001) (45)
- Expression of dominant negative CREB reduces resistance to radiation of human melanoma cells. (1996) (45)
- Expression and transcriptional activity of Ap‐1, CRE, and URE binding proteins in B16 mouse melanoma subclones (1994) (45)
- Regulation of Endoplasmic Reticulum-associated Degradation by RNF5-dependent Ubiquitination of JNK-associated Membrane Protein (JAMP)* (2009) (43)
- Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137. (2004) (42)
- The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation (2015) (42)
- Structure-based design of covalent Siah inhibitors. (2013) (41)
- Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation (2015) (41)
- Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase. (2000) (41)
- PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. (2015) (41)
- c-Jun Regulates Phosphoinositide-dependent Kinase 1 Transcription (2009) (40)
- Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication (1988) (39)
- Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFα and suppression of NF-κB activities (2001) (39)
- Inhibition of homologue of Slimb (HOS) function sensitizes human melanoma cells for apoptosis. (1999) (39)
- SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. (2000) (38)
- Immunogenic, cellular, and angiogenic drivers of tumor dormancy‐a melanoma view (2016) (37)
- Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis (2000) (37)
- Detection of k-ras mutation in normal and malignant colonic tissues by an enriched PCR method. (1994) (37)
- Dysregulation of ubiquitin ligases in cancer. (2015) (36)
- Regulation of MAP Kinases by the VHR Dual-Specific Phosphatase – Implications for Cell Growth and Differentiation (2006) (36)
- Enhancement of major histocompatibility class I protein synthesis by DNA damage in cultured human fibroblasts and keratinocytes (1989) (35)
- Dose rate and mode of exposure are key factors in JNK activation by UV irradiation. (1996) (34)
- Synthetic lethality-mediated precision oncology via the tumor transcriptome (2021) (34)
- Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127–189 of c-myc (2002) (34)
- Aldolase-DNA interactions in a SEWA cell system. (1992) (33)
- Effects of chemopreventive selenium compounds on Jun N-kinase activities. (1996) (33)
- Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB. (2001) (33)
- Identification of a Glutathione-S-Transferase Effector Domain for Inhibition of jun Kinase, by Molecular Dynamics (1999) (33)
- The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities (2010) (33)
- SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation (2019) (32)
- Identification of ultraviolet-inducible proteins that bind to a TGACAACA sequence in the polyoma virus regulatory region. (1990) (32)
- Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2 (2014) (32)
- Siah1/SIP regulates p27kip1 stability and cell migration under metabolic stress (2011) (32)
- Rapid activation of JNK1 in UV-B irradiated epidermal keratinocytes (1998) (31)
- Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis (2018) (30)
- Deciphering the mammalian stress response – a stressful task (1999) (30)
- SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth (2017) (30)
- Ubiquitin Ligases in Cancer Immunotherapy - Balancing Antitumor and Autoimmunity. (2019) (29)
- Adaptive Stress Responses During Tumor Metastasis and Dormancy. (2016) (29)
- Detection of ki-ras mutation in nonneoplastic mucosa of Japanese patients with colorectal cancers. (1994) (28)
- Fbx8 makes Arf6 refractory to function via ubiquitination. (2007) (28)
- Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate. (1994) (28)
- Selective in vivo stimulation of stress-activated protein kinase in different rat tissues by immobilization stress. (1998) (27)
- Induction of asynchronous replication of polyoma DNA in rat cells by ultraviolet irradiation and the effects of various inhibitors. (1987) (27)
- Reciprocal Relationships between the Resistance to Stresses and Cellular Aging a (1998) (27)
- Requirements for PKC-augmented JNK activation by MKK4/7. (2008) (27)
- Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide. (1994) (27)
- SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. (2015) (26)
- Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents (1997) (24)
- UV‐responsive element (TGACAACA) from rat fibroblasts to human melanomas (1994) (24)
- Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy (2015) (24)
- Inhibition of pkc and pka by chemopreventive organoselenium compounds. (1995) (24)
- Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities. (2001) (23)
- Effects of linoleic-Acid on mammary-tumor cell-proliferation are associated with changes in p53 protein expression. (1993) (23)
- Functional role of the ultraviolet light responsive element (URE; TGACAACA) in the transcription and replication of polyoma DNA. (1992) (23)
- Effects of 8-methoxypsoralen and ultraviolet light A on EGF receptor (HER-1) expression. (1988) (22)
- Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability (2013) (22)
- K‐ras mutation in sputum of patients with or without lung cancer (1996) (22)
- Evidence that oocyte maturation induced by an oncogenic ras-p21 protein and insulin is mediated by overlapping yet distinct mechanisms. (1992) (22)
- Balancing Mdm2 — a Daxx–HAUSP matter (2006) (22)
- Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice. (2010) (21)
- Monoubiquitination in proteasomal degradation (2016) (21)
- Transformation/Transcription Domain-Associated Protein (TRRAP)-Mediated Regulation of Wee1 (2010) (21)
- BI‐69A11‐mediated inhibition of AKT leads to effective regression of xenograft melanoma (2009) (21)
- The gut microbiome: an unexpected player in cancer immunity (2019) (20)
- JNKing Revealed. (2004) (20)
- Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK-MAP kinase signal transduction pathway (2000) (20)
- Dietary N‐3 fatty acids do not affect induction of Ha‐ras mutations in mammary glands of NMU‐treated rats (1991) (19)
- The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes (2018) (18)
- JAMP, a Jun N-Terminal Kinase 1 (JNK1)-Associated Membrane Protein, Regulates Duration of JNK Activity (2005) (18)
- JAMP optimizes ERAD to protect cells from unfolded proteins. (2008) (18)
- Inducible cellular responses to ultraviolet light irradiation and other mediators of DNA damage in mammalian cells (2004) (18)
- Synthesis and SAR Studies of Dual AKT/NF‐κB Inhibitors Against Melanoma (2013) (17)
- Phosphorylation of MdmX by CDK2/Cdc2p34 is required for nuclear export of Mdm2 (2005) (17)
- Melanoma biology and progression. (2001) (17)
- Melanoma‐initiating cells: a compass needed (2009) (17)
- Analysis of mutagenic activity and ability to induce replication of polyoma DNA sequences by different model metabolites of the carcinogenic tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. (1992) (17)
- Inhibition of Melanoma Growth by Small Molecules That Promote the Mitochondrial Localization of ATF2 (2013) (17)
- Inhibition of melanoma development in the Nras(Q61K)::Ink4a−/− mouse model by the small molecule BI‐69A11 (2013) (16)
- Quantitative enriched PCR (QEPCR), a highly sensitive method for detection of K‐ras oncogene mutation (1997) (16)
- A comparison of techniques for introducing macromolecules into living cells. (1993) (16)
- Autophosphorylation Properties of Inactive and Active JNK2 (2007) (15)
- (Auto)antibodies in human breast cancer sera against antigens associated with breast cancer cells, detected by immunoblotting. (1986) (15)
- A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis. (2016) (15)
- Fusarium moniliforme metabolites: genotoxicity of culture extracts. (1988) (14)
- Right on TARGET: glutamine metabolism in cancer (2015) (14)
- Gene mutation as a target for early detection in cancer diagnosis. (2001) (14)
- A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing (2021) (14)
- p73 transcriptional activity increases upon cooperation between its spliced forms (2000) (13)
- Impaired jun-NH2-terminal kinase activation by ultraviolet irradiation in fibroblasts of patients with Cockayne syndrome complementation group B. (1996) (13)
- Identification of an intracellular protein that specifically interacts with photoaffinity-labeled oncogenic p21 protein. (1989) (13)
- A transcriptional inhibitor induced in human melanoma cells upon ultraviolet irradiation. (1993) (12)
- A simple and efficient method for the purification of specific DNA binding proteins. (1992) (12)
- ras oncogene detection in pre-neoplastic lesions: possible applications for diagnosis and prevention. (1992) (12)
- Combined analysis of microsatellite instability and K-ras mutation increases detection incidence of normal samples from colorectal cancer patients. (1997) (12)
- Inhibition of ras-oncogene-encoded p21 protein-induced maturation of oocytes by p21 peptide sequences predicted to be effector domain sites by molecular modelling (1992) (12)
- Siah2 control of T-regulatory cells limits anti-tumor immunity (2020) (12)
- Muscle–epidermis interactions affect exoskeleton patterning in Caenorhabditis elegans (2007) (12)
- Complexes of ras-p21 with jun-N-kinase (1996) (12)
- The masters talk: the PGC‐1α–MITF axis as a melanoma energizer (2013) (11)
- IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells (2021) (11)
- Rewired Notch/p53 by Numb’ing Mdm2 (2018) (11)
- Inhibition of ras oncogene-encoded P21 protein-induced pinocytotic activity by a synthetic peptide corresponding to an effector domain of the protein (1990) (11)
- Identification and Characterization of IMD-0354 as a Glutamine Carrier Protein Inhibitor in Melanoma (2021) (11)
- A New Function for p53 Ubiquitination (2006) (11)
- Unfolded Protein Response in Leukemia: From Basic Understanding to Therapeutic Opportunities. (2020) (11)
- Effective inhibition of melanoma by BI‐69A11 is mediated by dual targeting of the AKT and NF‐κB pathways (2011) (11)
- Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells. (2019) (10)
- SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth (2020) (10)
- Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway. (2000) (10)
- Sampling method as a key factor in identifying K-ras oncogene mutations in preneoplastic colorectal lesions. (1995) (10)
- The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors (2021) (10)
- Harnessing the Co-vulnerabilities of Amino Acid-Restricted Cancers. (2021) (10)
- The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion. (2017) (9)
- MAPK signaling regulates c‐MYC for melanoma cell adaptation to asparagine restriction (2021) (9)
- Regulation of eIF2α by RNF4 promotes melanoma tumorigenesis and therapy resistance. (2020) (9)
- Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax (2020) (9)
- An ATF 2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis (2002) (9)
- Increased Expression of the E 3 Ubiquitin Ligase RNF 5 Is Associated with Decreased Survival in Breast Cancer (2007) (9)
- Track record? (2012) (9)
- Advances in Brief Glutathione S-Transferase p Elicits Protection against H 2 O 2-induced Cell Death via Coordinated Regulation of Stress Kinases 1 (2000) (8)
- Expression pattern of proteins that bind to the ultraviolet‐responsive element (TGACAACA) in human keratinocytes (1993) (8)
- Changes in jun N‐terminal kinase activation by stress during aging of cultured normal human fibroblasts (1996) (8)
- The Mdm2 Amino Terminus Is Required for Mdm 2 Binding and SUMO-1 Conjugation by the E 2 SUMO-1 Conjugating Enzyme Ubc 9 * (2001) (7)
- Phosphorylation of MdmX by CDK2/Cdc2p34 is required for nuclear export of Mdm2 (2005) (6)
- The Anaphase-Promoting Complex or Cyclosome Supports Cell Survival in Response to Endoplasmic Reticulum Stress (2012) (6)
- Distinct pattern of p53 phosphorylation in human cancers (2003) (6)
- Comparative mouse skin tumorigenicity and induction of Ha-ras mutations by bay region diol epoxides of 5-methylchrysene and 5,6-dimethylchrysene. (1998) (6)
- Analysis of mutant K-ras in multiple sites of normal appearing mucosa of colorectal cancer patients. (1996) (5)
- Ubiquitin-Conjugating Enzyme Ubc13 Is a Critical Component of TRAF-Mediated Inflammatory Responses. (2006) (5)
- Ultraviolet light‐responsive element (TGACAACA,) ‐binding proteins in cells of xeroderma pigmentosum patients (1995) (5)
- The SCF-ROC1 E3 Ubiquitin Ligase Utilizes Two Distinct Domains within CUL1 for Substrate Targeting and Ubiquitin Ligation (2000) (5)
- RACK 1 Function in Cell Motility and Protein Synthesis (2013) (5)
- Modulation of carcinogen-induced polyoma DNA-replication by organoselenium and organosulfur chemopreventive agents. (1993) (5)
- Roadmap for new opportunities in melanoma research. (2007) (5)
- Metabolism in melanoma metastasis (2016) (5)
- MUTUAL DEPENDENCE OF JUN-N-TERMINAL KINASE AND PROTEIN KINASE C ON THE ONCOGENIC RAS-P21 PROTEIN-INDUCED MITOGENIC SIGNALLING PATHWAY (1998) (5)
- Regulation of c-jun by lung carcinogens in Clara cells of hamsters. (1994) (4)
- A 43 kDa protein (p43) that interacts with the ras-oncogene-encoded p21 protein strongly induces maturation of oocytes (1992) (4)
- Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice (2019) (4)
- Anti-red blood cell autoantibodies induced in rat by Plasmodium berghei infection bind to a cross-reacting determinant present also in other cell types. (1983) (4)
- PEBP2--a modulator of polyoma DNA replication. (1994) (4)
- Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome (2022) (4)
- Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing (2018) (4)
- A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML (2020) (3)
- HIV Drug to Aid Melanoma Therapies? (2016) (3)
- Ultraviolet irradiation and c-jun over-expression regulates replication of polyoma sequences in WOP cells through a PEBP2 binding site. (1995) (3)
- Altered Signal Transduction in Melanoma (2006) (3)
- Effect of dietary fatty acids on gene expression in breast cells. (1995) (3)
- Abstract 2440: RNF5 mediates ER stress-induced degradation of SLC1A5 in breast cancer (2014) (3)
- PKC ε regulates ATF 2 availability to alter mitochondrial permeability following genotoxic stress (2013) (3)
- EVIDENCE THAT SIGNAL TRANSDUCTION BY ONCOGENIC RAS-P21 PROTEIN DEPENDS ON ITS INTERACTION WITH JUN KINASE AND JUN PROTEINS (1996) (3)
- Autoantibodies to red blood cells in rats infected with Plasmodium berghei. (1981) (3)
- Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance (2021) (3)
- Tricking melanoma to self-digest: a deal of a meal! (2009) (2)
- NRF2 mediates melanoma addiction to GCDH by modulating apoptotic signalling (2022) (2)
- Correction for Zhang et al., RACK1 Recruits STAT3 Specifically to Insulin and Insulin-Like Growth Factor 1 Receptors for Activation, Which Is Important for Regulating Anchorage-Independent Growth (2017) (2)
- ATF2 alters melanocyte response and macrophage recruitment in UV‐irradiated neonatal mouse skin (2015) (2)
- Serial circulating immune complex values and development of metastatic disease in breast cancer and malignant melanoma patients (2004) (2)
- Interaction of SEWA sarcoma cell proteins with the intracisternal A‐type particle long terminal repeat dna sequence (1992) (2)
- Expression of a 32 kDa protein in rat mammary tumors induced by anti‐benzo[c]phenanthrene‐3,4‐diol‐1,2‐epoxide (1996) (2)
- Induction of b-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-kB* (2001) (2)
- GENERAL PURPOSE LAMPS INDUCE POLYOMA DNA REPLICATION IN H3 CELLS (1993) (2)
- The pigmented road ahead – success through collaboration (2010) (2)
- [Detection of mast cells in bronchoalveolar lavage with various stains]. (1993) (2)
- Mice enhance their image (2011) (2)
- Abstract 69: Functional metabolomic profiling of human melanocyte and melanoma cells during hypoxic adaptation (2010) (1)
- A JAK/STAT-MEDIATED INFLAMMATORY SIGNALING CASCADE DRIVES ONCOGENESIS IN AF10-REARRANGED AML. (2021) (1)
- Faculty Opinions recommendation of Stat3 dimerization regulated by reversible acetylation of a single lysine residue. (2005) (1)
- Lipid metabolism: new twists to the Yin and Yang of PKM2 in cancer (2021) (1)
- RAF-isotype switching: from B to C through PDE (2011) (1)
- RNF5-deficiency inhibits CD8+ T cell exhaustion in chronic antigen stimulation (2021) (1)
- Elevated binding to URE/PEBP2 during the late stages of NNK and benzo[a]pyrene-induced carcinogenesis in A/J mice. (1996) (1)
- Abstract 59: PDK1 in melanoma development and metastasis (2014) (1)
- Erratum to The E3Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity [Cancer Cell 23, (2013) 332-346] (2013) (1)
- Expression of ring ® nger-deleted TRAF 2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p 38 , TNF a and suppression of NFk B activities (2001) (1)
- Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing (2022) (1)
- The UPs and DOWNs of MITF in melanoma resistance (2015) (1)
- SIAH2 (seven in absentia homolog 2 (Drosophila)) (2012) (1)
- Altered Signal Transduction Pathways in Melanoma (2011) (1)
- Advances in Brief p 53 Phosphorylation and Association with Murine Double Minute 2 , c-Jun NH 2-Terminal Kinase , p 14 ARF , and p 300 / CBP during the Cell Cycle and after Exposure to Ultraviolet Irradiation 1 (2000) (1)
- Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function (2021) (0)
- RNF5 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors (2020) (0)
- Advances in Brief Inhibition of Homologue of Slimb ( HOS ) Function Sensitizes Human Melanoma Cells for Apoptosis 1 (1999) (0)
- [Ubiquitin system in hypoxia response]. (2006) (0)
- Regulators and Effectors of Siah Ubiquitin Ligases (2013) (0)
- Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer (2015) (0)
- E-101 UPR in coordinated regulation of microbiome and anti-tumor immunity (2019) (0)
- Apoptosis: Cell Death in Response to Genotoxic Stress and DNA Damage (2011) (0)
- A complex but promising therapy (2010) (0)
- Flipping or scrolling (2010) (0)
- Stability of mutant p53 proteins (2003) (0)
- Abstract 957: Prediction of patient response to targeted and immunotherapies from the tumor transcriptome in a wide set of indications and clinical trials (2023) (0)
- Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR (2013) (0)
- It’s a small (integrated multidisciplinary) world (2012) (0)
- Control of alveolar macrophage differentiation by Siah1a/2 ubiquitin ligases limits carcinogen-induced lung adenocarcinoma (2022) (0)
- Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex (2022) (0)
- Faculty Opinions recommendation of Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. (2010) (0)
- A Unique Crosstalk between Tumor Cells and Hematopoietic Stem Cells Reveals a Myeloid Differentiation Pattern Signature Contributing to Metastasis (2019) (0)
- Faculty Opinions recommendation of XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. (2014) (0)
- Translational reprogramming marks adaptation to asparagine restriction in cancer (2019) (0)
- MITF – past, present and future (2010) (0)
- Siah1/2 Ubiquitin Ligases in ER Stress Signaling in Melanoma (2015) (0)
- Abstract 1886: A novel inhibitor of eIF4F protein translation complex sensitizes DLBCL cells to BCL-2 targeted therapy (2018) (0)
- Faculty of 1000 evaluation for Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS(+)/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy. (2013) (0)
- Faculty Opinions recommendation of Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation. (2013) (0)
- Casper: A phase I, open-label, dose finding study of calaspargase pegol-mnkl (cala) in combination with cobimetinib (cobi) in locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC). (2023) (0)
- Research – endure! (2011) (0)
- Takashi Sugimura (1926-2020). (2020) (0)
- Faculty of 1000 evaluation for Chromosomal instability drives metastasis through a cytosolic DNA response. (2018) (0)
- Siah1 bound to synthetic peptide (ACE)KLRPVAMVRP(PRK)VR (2013) (0)
- Faculty Opinions recommendation of Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy. (2014) (0)
- Faculty Opinions recommendation of A direct role for Met endocytosis in tumorigenesis. (2011) (0)
- Downregulating FUK to Get Unstuck: Altered Fucosylation in Melanoma Promotes Tumor Development and Metastasis (2016) (0)
- Abstract PR18: Comparative screening of skin-derived NCSCs, melanocytes, and melanoma developmental programs reveals LPAR1 in MAPKi resistance (2020) (0)
- Chapter 19 Oxidative stress signaling (2001) (0)
- The rush to publish (2011) (0)
- Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR (2013) (0)
- Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development (2020) (0)
- Antibodies and immune complexes in sera of breast cancer patients (1986) (0)
- 502 Low GRP78 protein level predicts response to PD1 therapy and good prognosis in melanoma (2019) (0)
- Faculty Opinions recommendation of Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size. (2018) (0)
- CALPA-IN NF1 (2018) (0)
- Abstract 4520: Inhibition of melanoma growth by small molecules that attenuate PI3K/PDK1 signaling and promote ATF2 mitochondrial localization (2014) (0)
- Arginyl‐tRNA‐protein transferase 1 (ATE1) promotes melanoma cell growth and migration (2022) (0)
- Faculty Opinions recommendation of Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. (2005) (0)
- AWARD NUMBER: W81XWH-14-1-0551 TITLE: Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer PRINCIPAL INVESTIGATOR: Ze’ev Ronai RECIPIENT: Sanford-Burnham-Prebys Medical Discovery Institute (2016) (0)
- Faculty Opinions recommendation of The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC. (2020) (0)
- RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors (2020) (0)
- Heath education for asthmatic children — 2 years of experience (1994) (0)
- Melanoma initiating cells – easy as ABC? (2008) (0)
- Faculty Opinions recommendation of Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms. (2006) (0)
- 1154 RNF125 CONTROL OF THE HISTONE DEACETYLASE HDAC2 SUPPORTS ACINAR IDENTITY AND INHIBITS THE PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA (2020) (0)
- The Role of the Ubiquitin–Proteasome Pathway in the Regulation of the Cellular Hypoxia Response (2007) (0)
- Faculty Opinions recommendation of Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. (2009) (0)
- It’s in our roots (2011) (0)
- Siah2 control of T-regulatory cells limits anti-tumor immunity (2020) (0)
- Carcinogen-Inducible Proteins as Mediators of Asynchronous Replication of DNA Tumor Viruses (2020) (0)
- A darker side to p53. (2007) (0)
- 1155 CO-TARGETING MAPK SIGNALING AND ASPARAGINE METABOLISM BY MEK INHIBITOR + L-ASPARAGINASE COMBINATION IN PANCREATIC CANCER (2020) (0)
- Effects of peptides from oncogene-related proteins on replication of polyoma DNA sequences (1994) (0)
- Abstract P291: The Ubiquitin Ligase Siah2 in Cardiac Response to Ischemia (2011) (0)
- Effect of Specific Fatty Acids on p53 Expression in Rat Mammary Tumor Cells (1994) (0)
- Polyoma DNA replication dependent upon growth condition of SEWA sarcoma cells (1990) (0)
- Tumor-educated monocyte-dendritic progenitors promote a metastatic switch (2020) (0)
- 1207 RNF4 ubiquitin ligase drives melanoma progression (2018) (0)
- Faculty Opinions recommendation of AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. (2009) (0)
- I. Bernard Weinstein September 9, 1930–November 3, 2008 (2008) (0)
- Abstract 1795: Small molecule SBI-601 inhibits Siah1/2 ubiquitin ligases, attenuates HIF1α expression and growth of melanoma and prostate cancer cells (2014) (0)
- Faculty Opinions recommendation of Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. (2007) (0)
- Faculty Opinions recommendation of Gene expression and cell identity controlled by anaphase-promoting complex. (2020) (0)
- AWARD NUMBER: W81XWH-14-1-0551 TITLE: Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer PRINCIPAL INVESTIGATOR: (2015) (0)
- Ubiquitin ligases Siah1a/2 control alveolar macrophage functions to limit carcinogen-induced lung adenocarcinoma. (2023) (0)
- Abstract 5456: The E3 ubiquitin ligase Siah2 regulates the androgen receptor activity and contributes to castration-resistant prostate cancer. (2013) (0)
- Tumor-educated uncommitted hematopoietic stem cells promote a metastatic switch (2020) (0)
- Faculty Opinions recommendation of Central role of p53 in the suntan response and pathologic hyperpigmentation. (2007) (0)
- Mouse models as drivers in defining new targets for therapies-Examples from prostate cancer melanoma studies (2014) (0)
- Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection (2020) (0)
- Faculty Opinions recommendation of The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation. (2012) (0)
- Faculty Opinions recommendation of A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. (2005) (0)
- Abstract 4091: Interfering with interferon: An axis of ATF2-mediated chemoresistance (2014) (0)
- Educational tools for the health education of asthmatic children (1994) (0)
- Faculty Opinions recommendation of O2 regulates stem cells through Wnt/β-catenin signalling. (2010) (0)
- Faculty Opinions recommendation of mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. (2005) (0)
- SLC1A5 to predict outcome with chemotherapy in early triple-negative breast cancer. (2015) (0)
- Faculty Opinions recommendation of Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. (2017) (0)
- Abstract IA17: Strategies to target the mTORC1/eIF4F axis in B-cell leukemia and lymphoma (2020) (0)
- Faculty Opinions recommendation of Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. (2022) (0)
- Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunity (2022) (0)
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