Zemin Wang
#186,480
Most Influential Person Now
Researcher ORCID 0000-0002-8784-8105
Zemin Wang's AcademicInfluence.com Rankings
Zemin Wangengineering Degrees
Engineering
#8867
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#10496
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Electrical Engineering
#2785
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#2928
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Zemin Wangcomputer-science Degrees
Computer Science
#12135
World Rank
#12934
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Computational Linguistics
#3053
World Rank
#3089
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Machine Learning
#5564
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#5638
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Artificial Intelligence
#6007
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#6099
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Engineering Computer Science
Zemin Wang's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Electrical Engineering Tsinghua University
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Why Is Zemin Wang Influential?
(Suggest an Edit or Addition)Zemin Wang's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Control of Peripheral Nerve Myelination by the ß-Secretase BACE1 (2006) (708)
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis (2014) (580)
- A γ‐secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish (2002) (515)
- Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. (2001) (463)
- η-Secretase processing of APP inhibits neuronal activity in the hippocampus (2015) (306)
- Loss of TREM2 function increases amyloid seeding but reduces plaque associated ApoE (2018) (291)
- A Critical Function of the Pial Basement Membrane in Cortical Histogenesis (2002) (284)
- Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons (2012) (284)
- Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. (2012) (272)
- Phosphorylation Regulates Intracellular Trafficking of β-Secretase* (2001) (257)
- Maturation and Pro-peptide Cleavage of β-Secretase* (2000) (234)
- Insulin-degrading Enzyme Rapidly Removes the β-Amyloid Precursor Protein Intracellular Domain (AICD)* (2002) (216)
- The β-Secretase BACE1 in Alzheimer’s Disease (2020) (202)
- Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development. (2002) (201)
- Amyloid Precursor Protein and Notch Intracellular Domains are Generated after Transport of their Precursors to the Cell Surface (2006) (158)
- Impaired Axonal Regeneration in α7 Integrin-Deficient Mice (2000) (157)
- Gene transfer into CD4+ T lymphocytes: Green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses (1999) (154)
- Phosphorylation regulates intracellular trafficking of beta-secretase. (2001) (150)
- Rescue of Progranulin Deficiency Associated with Frontotemporal Lobar Degeneration by Alkalizing Reagents and Inhibition of Vacuolar ATPase (2011) (141)
- Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles (2013) (127)
- A non‐amyloidogenic function of BACE‐2 in the secretory pathway (2002) (127)
- Neuronal FasL Induces Cell Death of Encephalitogenic T Lymphocytes (2000) (120)
- Young microglia restore amyloid plaque clearance of aged microglia (2017) (113)
- Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions (2013) (110)
- Dual Cleavage of Neuregulin 1 Type III by BACE1 and ADAM17 Liberates Its EGF-Like Domain and Allows Paracrine Signaling (2013) (108)
- Maturation and pro-peptide cleavage of beta-secretase. (2000) (105)
- Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region (2020) (100)
- Impaired axonal regeneration in alpha7 integrin-deficient mice. (2000) (99)
- Dimerization of β-Site β-Amyloid Precursor Protein-cleaving Enzyme* (2004) (98)
- Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy. (2006) (95)
- PPARγ co-activator-1α (PGC-1α) reduces amyloid-β generation through a PPARγ-dependent mechanism. (2011) (93)
- Deficiency of Aph1B/C-γ-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment (2008) (90)
- Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. (2016) (86)
- Function, regulation and therapeutic properties of beta-secretase (BACE1). (2009) (83)
- Constitutive properties, not molecular adaptations, mediate extraocular muscle sparing in dystrophic mdx mice (2003) (80)
- Basement membrane-dependent survival of retinal ganglion cells. (2005) (77)
- Translational Repression of the Disintegrin and Metalloprotease ADAM10 by a Stable G-quadruplex Secondary Structure in Its 5′-Untranslated Region* (2011) (73)
- Organization of the myotendinous junction is dependent on the presence of alpha7beta1 integrin. (1999) (73)
- BACE1 Processing of NRG1 Type III Produces a Myelin-Inducing Signal but Is Not Essential for the Stimulation of Myelination (2011) (71)
- Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer’s disease brain (2018) (69)
- Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content (2007) (68)
- Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein (2019) (64)
- BACE1 dependent neuregulin processing: review. (2012) (64)
- Identification of a β-Secretase Activity, Which Truncates Amyloid β-Peptide after Its Presenilin-dependent Generation* (2003) (61)
- Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models (2019) (60)
- Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes (2013) (60)
- Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases (2021) (53)
- Defective integrin switch and matrix composition at alpha 7-deficient myotendinous junctions precede the onset of muscular dystrophy in mice. (2003) (52)
- beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice. (2004) (50)
- Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme. (2004) (45)
- Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases (2015) (37)
- Proteolytic processing of Neuregulin-1 (2016) (35)
- Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein. (2017) (23)
- Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation (2018) (23)
- Macrocyclic Statine‐Based Inhibitors of BACE‐1 (2007) (21)
- Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein (2017) (20)
- Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models (2020) (18)
- Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation (2020) (12)
- Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice (2020) (12)
- Secreted APP Modulates Synaptic Activity: A Novel Target for Therapeutic Intervention? (2019) (11)
- Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease (2021) (11)
- -Site Amyloid Precursor Protein Cleaving Enzyme 1 Increases Amyloid Deposition in Brain Parenchyma but Reduces Cerebrovascular Amyloid Angiopathy in Aging BACE APP[V717I] Double-Transgenic Mice (2004) (10)
- The b-Secretase BACE1 in Alzheimer’s Disease (2020) (10)
- Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor (2009) (9)
- BACE1 Dependent Neuregulin Proteolysis. (2011) (9)
- Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis (2018) (9)
- Analysis of Age-Dependent Alterations in Excitability Properties of CA1 Pyramidal Neurons in an APPPS1 Model of Alzheimer’s Disease (2021) (7)
- Lack of β-amyloid cleaving enzyme-1 (BACE1) impairs long-term synaptic plasticity but enhances granule cell excitability and oscillatory activity in the dentate gyrus in vivo (2019) (7)
- Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease (2021) (7)
- Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation (2021) (6)
- University of Groningen Controlled Gene Expression Systems for Lactococcus lactis with the Food-Grade Inducer (1996) (6)
- Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia (2022) (5)
- Identification of a rare presenilin 1 single amino acid deletion mutation (F175del) with unusual amyloid-β processing effects (2019) (5)
- PHOSPHORYLATION REGULATES INTRACELLULAR TRAFFICKING OF ß-SECRETASE ( BACE ) (2001) (4)
- Specific Inhibition of b-Se cretase Processing of the Alzheimer Disease Amyloid Precursor Protein (2016) (3)
- Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition (2021) (3)
- A molecular view of human amyloid-β folds. (2022) (3)
- Specific Inhibition of bSe cretase Processing of the Alzheimer Disease Amyloid Precursor Protein Graphical (2016) (2)
- [Mechanisms of Alzheimer's disease : Neuronal hyperactivity and hypoactivity as new therapeutic targets]. (2016) (2)
- Glitter in the darkness? Non‐fibrillar β‐amyloid plaque components significantly impact the β‐amyloid PET signal (2021) (2)
- P3-259 Neuregulin-1 is a BACE1 substrate (2006) (1)
- Author response: Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein (2017) (1)
- Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo (2021) (1)
- P3-257: BACE1 cleavage and release of neuregulin-1 determines the ensheathment fate of axons (2006) (1)
- Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo (2021) (0)
- Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease. (2022) (0)
- Inhibition of b-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein (2016) (0)
- Therapeutic potential of BACE1/beta-secretase: Proteome-wide identification of physiological BACE1 substrates in primary neurons and mouse brain (2012) (0)
- Cyclic statine-based peptides as inhibitors of β-secretase (2006) (0)
- Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model (2022) (0)
- for Donor Counterselection R2f φ Bacteria in Soil by Using Bacteriophage Pseudomonas fluorescens to Indigenous Detection of Plasmid Transfer from (2013) (0)
- P1-032: BACE1 dependent proteolysis of neuregulin in vitro and in vivo (2008) (0)
- P3-260 BACE1 regulation in down syndrome (2006) (0)
- Distinct functions of BACE1 and BACE2 in neuregulin processing and melanocyte migration (2013) (0)
- O4-04-06 β-Amyloid precursor protein intracellular domain (AICD) strongly enhances resting free cytosolic calcium levels (2004) (0)
- Biological consequences of BACE1-dependent processing of neuregulin (2011) (0)
- Chapter V New immunoassay for the detection of Helicobacter pylori infection compared with urease test , 13 C breath test and histology : validation in the primary care setting (2002) (0)
- P2-371: Characterization of cell-permeable BACE-1 inhibitors in primary neurons and mice (2008) (0)
- University of Groningen Improvement of Solubility and Stability of the Antimicrobial Peptide Nisin by Protein Engineering Rollema, (1995) (0)
- Neuropathological characteristics associated with a recently identified rare PSEN1 deletion mutation (F175del) (2020) (0)
- Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice (2023) (0)
- Subject Index Vol. 6, 2009 (2010) (0)
- Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation (2020) (0)
- Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE (2019) (0)
- Identification of an alternative APP processing pathway (2013) (0)
- Contents Vol. 6, 2009 (2010) (0)
- Lack of β-amyloid cleaving enzyme-1 (BACE1) impairs long-term synaptic plasticity but enhances granule cell excitability and oscillatory activity in the dentate gyrus in vivo (2019) (0)
- Expression , and Diversity Gram-Positive Cocci : Complementation , and Other Lactococcus lactis Genes from Functional Analysis of Glycosyltransferase (1999) (0)
- Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia (2022) (0)
- Impact of the presence of AβN3pE and AβpSer8 in Aβ aggregates on the induction of Aβ seeding and spreading in the brains of APP23 mice (2020) (0)
- Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein (2022) (0)
- Isolation and characterization of plasmids from different strains of Methanobacterium thermo formicicum (2008) (0)
- Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis (2018) (0)
- Functions of the protease bace1 in the maturation of the nervous system (2006) (0)
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Zemin Wang is affiliated with the following schools: