Zoi Lygerou
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Italian biologist
Zoi Lygerou's AcademicInfluence.com Rankings
Zoi Lygeroubiology Degrees
Biology
#9844
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#13095
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Cell Biology
#876
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#898
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Molecular Biology
#2372
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#2409
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Biology
Zoi Lygerou's Degrees
- Bachelors Biology University of Milan
- PhD Cell Biology University of Florence
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Why Is Zoi Lygerou Influential?
(Suggest an Edit or Addition)According to Wikipedia, Zoi Lygerou is a Greek molecular biologist and associate professor at Patras Medical School. Lygerou's works have been published in such journals as the European Journal of Biochemistry, Journal of Cell Science, the Molecular and Cellular Biology journal, Journal of Biological Chemistry, and both Science and Nature journals among others. She is especially known for her work on cell cycle control mechanisms in eukaryotic organisms, and has done research at the University of Patras since 1999. Lygerou has also held positions at the European Molecular Biology Laboratory and at the Imperial Cancer Research Fund in London under Paul Nurse.
Zoi Lygerou's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Cdt1 protein is required to license DNA for replication in fission yeast (2000) (507)
- Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis (2006) (395)
- The Human Licensing Factor for DNA Replication Cdt1 Accumulates in G1 and Is Destabilized after Initiation of S-phase* (2001) (274)
- Control of DNA replication licensing in a cell cycle (2002) (272)
- Accurate Processing of a Eukaryotic Precursor Ribosomal RNA by Ribonuclease MRP in Vitro (1996) (271)
- Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. (2007) (204)
- The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. (1994) (195)
- Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1. (2004) (183)
- easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data (2012) (152)
- Proteolysis of DNA Replication Licensing Factor Cdt1 in S-phase Is Performed Independently of Geminin through Its N-terminal Region* (2004) (146)
- Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines. (2004) (123)
- Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication (2001) (110)
- hPop1: an autoantigenic protein subunit shared by the human RNase P and RNase MRP ribonucleoproteins. (1996) (96)
- Stochastic hybrid modeling of DNA replication across a complete genome (2008) (85)
- Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche (2015) (85)
- The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs. (1994) (82)
- Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin (2007) (79)
- Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing (2009) (79)
- EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data (2018) (79)
- Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world? (2014) (77)
- DNA replication licensing. (2004) (75)
- GemC1 controls multiciliogenesis in the airway epithelium (2016) (68)
- The fission yeast origin recognition complex is constitutively associated with chromatin and is differentially modified through the cell cycle. (1999) (66)
- Control over DNA replication in time and space (2012) (65)
- A Novel Genetic Screen for snRNP Assembly Factors in Yeast Identifies a Conserved Protein, Sad1p, Also Required for Pre-mRNA Splicing (1999) (62)
- Replication Licensing Aberrations, Replication Stress, and Genomic Instability. (2019) (59)
- Geminin Regulates Cortical Progenitor Proliferation and Differentiation (2011) (55)
- Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle (2007) (49)
- Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (2017) (48)
- Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression* (2011) (46)
- Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage (2011) (46)
- License Withheld--Geminin Blocks DNA Replication (2000) (43)
- Cdt1 Interactions in the Licensing Process: A Model for Dynamic Spatio-temporal Control of Licensing (2007) (37)
- Differential Geminin Requirement for Proliferation of Thymocytes and Mature T Cells (2010) (35)
- Cell cycle. License withheld--geminin blocks DNA replication. (2000) (35)
- Multi-step Loading of Human Minichromosome Maintenance Proteins in Live Human Cells* (2013) (33)
- Geminin Cleavage during Apoptosis by Caspase-3 Alters Its Binding Ability to the SWI/SNF Subunit Brahma* (2007) (32)
- A Custom Ultra-Low-Cost 3D Bioprinter Supports Cell Growth and Differentiation (2020) (29)
- Cdt1 Is Differentially Targeted for Degradation by Anticancer Chemotherapeutic Drugs (2012) (29)
- Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors (2015) (29)
- Geminin ablation in vivo enhances tumorigenesis through increased genomic instability (2018) (29)
- DNA replication in the fission yeast: robustness in the face of uncertainty (2006) (27)
- CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation (2015) (27)
- The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing* (2013) (24)
- How a radial glial cell decides to become a multiciliated ependymal cell (2017) (23)
- GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73 (2019) (20)
- Life without geminin (2010) (19)
- The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins (2015) (19)
- Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis (2018) (19)
- Concise Review: Geminin—A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells (2017) (18)
- CRL4Cdt2: Coupling Genome Stability to Ubiquitination. (2020) (18)
- Reduced Geminin levels promote cellular senescence (2013) (14)
- Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1 (2018) (14)
- GemC1 is a critical switch for neural stem cell generation in the postnatal brain (2019) (14)
- The Licensing Factor Cdt1 Links Cell Cycle Progression to the DNA Damage Response (2020) (13)
- IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover. (2016) (12)
- Analysis of Protein Kinetics Using Fluorescence Recovery After Photobleaching (FRAP). (2017) (12)
- T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin. (2011) (12)
- Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments (2014) (11)
- Cell Cycle-dependent Subcellular Translocation of the Human DNA Licensing Inhibitor Geminin* (2013) (11)
- Mcidas and GemC1/Lynkeas specify embryonic radial glial cells (2016) (10)
- Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival (2020) (9)
- Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. (2016) (9)
- IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover. (2016) (8)
- Controlling S-phase onset in fission yeast. (2000) (8)
- Chromatin and Nuclear Architecture: Shaping DNA Replication in 3D. (2020) (7)
- The Cdt 1 protein is required to license DNA for replication in ® ssion yeast (7)
- Expression of α-Defensins, CD20+ B-lymphocytes, and Intraepithelial CD3+ T-lymphocytes in the Intestinal Mucosa of Patients with Liver Cirrhosis: Emerging Mediators of Intestinal Barrier Function (2018) (7)
- Numerical analysis of FRAP experiments for DNA replication and repair (2008) (6)
- Cortical Development and Brain Malformations: Insights From the Differential Regulation of Early Events of DNA Replication (2019) (6)
- Integrin-Linked-Kinase Overexpression Is Implicated in Mechanisms of Genomic Instability in Human Colorectal Cancer (2020) (6)
- Mismatch repair regulates Cdt1 after UV damage (2017) (6)
- Ribosomal DNA and the nucleolus at the heart of aging. (2022) (6)
- Fine‐tuning multiciliated cell differentiation at the post‐transcriptional level: contribution of miR‐34/449 family members (2021) (5)
- Fanconi anemia proteins and genome fragility: unraveling replication defects for cancer therapy. (2022) (5)
- Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma (2021) (5)
- Parameter Identification for a DNA replication model (2008) (3)
- Whole transcriptome data analysis of mouse embryonic hematopoietic stem and progenitor cells that lack Geminin expression (2016) (3)
- Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells (2022) (2)
- 3D Reconstitution of the Neural Stem Cell Niche: Connecting the Dots (2021) (2)
- Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (2018) (2)
- Geminin Participates in Differentiation Decisions of Adult Neural Stem Cells Transplanted in the Hemiparkinsonian Mouse Brain. (2017) (2)
- Visualizing the dynamics of histone variants in the S-phase nucleus (2018) (2)
- Ιn vivo imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex (2020) (2)
- A stochastic hybrid model of DNA replication incorporating 3D protein mobility dynamics (2019) (2)
- 53BP1‐mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling (2022) (2)
- Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress (2022) (1)
- Ras suppressor-1 (RSU1) exerts a tumor suppressive role with prognostic significance in lung adenocarcinoma (2022) (1)
- Title: Mcidas and GemC1/Lynkeas are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. (2015) (1)
- Metabolic regulation of the neural stem cell fate: Unraveling new connections, establishing new concepts (2022) (1)
- In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity (2020) (1)
- Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage (2022) (1)
- Visualizing the dynamics of histone variants in the S-phase nucleus (2018) (0)
- Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis (2017) (0)
- McIdas localizes at centrioles and controls centriole numbers through PLK4-dependent phosphorylation (2022) (0)
- Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (2022) (0)
- Maximal loading of MCM 2 / 4 in late G 1 1 Multi-step loading of human Mini Chromosome Maintenance proteins in live human cells * (2013) (0)
- RNA-seq and microarray Data Analysis related to skin psoriasis, Overview of Optimal Methods for RNA-seq Analysis and Application for Biomarker Discovery for Skin-related Disorders (2019) (0)
- Alterations in the spatiotemporal expression pattern of geminin during human epidermal morphogenesis. (2023) (0)
- Aberrant replication licensing drives Copy Number Gains across species (2020) (0)
- Oral Presentations (2008) (0)
- GEMININ IS ESSENTIAL FOR THE GENERATION AND DIFFERENTIATION OF ENTERIC NERVOUS SYSTEM PROGENITOR CELLS (2011) (0)
- DNA Replication Control: Liquid-liquid Phase Separation Comes Into Play. (2020) (0)
- TISSUE-SPECIFIC STEM CELLS Geminin Regulates Cortical Progenitor Proliferation and Differentiation (2011) (0)
- Focal adhesion proteins in hepatocellular carcinoma: RSU1 a novel tumour suppressor with prognostic significance. (2022) (0)
- Author Correction: Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (2022) (0)
- Running title : Geminin ablation in vivo enhances tumorigenesis Conflicts of Interest (2018) (0)
- Mature T Cells Proliferation of Thymocytes and Differential Geminin Requirement for (2010) (0)
- Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival (2020) (0)
- DNA for replication in ® ssion yeast (0)
- Geminin regulates self-renewal and fate commitment decisions in fetal hematopoietic stem cells (2014) (0)
- 53BP1 mediated recruitment of RASSF1A at ribosomal DNA breaks facilitates local ATM signal amplification (2021) (0)
- In silico analysis of DNA re-replication across a complete genome points to genome plasticity (2020) (0)
- Proliferation and differentiation defects of lymphoid lineage cells in mice that lack geminin (2008) (0)
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