Cynthia Kenyon | Academic Influence

Cynthia Kenyon's AcademicInfluence.com Rankings

Cynthia Kenyon

Biology

#394

World Rank

#705

Historical Rank

#235

USA Rank

Molecular Biology

#93

World Rank

#96

Historical Rank

#58

USA Rank

Genetics

#88

World Rank

#123

Historical Rank

#57

USA Rank

Biochemistry

#148

World Rank

#189

Historical Rank

#80

USA Rank

biology Degrees

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Biology

Cynthia Kenyon's Degrees

Bachelors Chemistry University of Georgia

Why Is Cynthia Kenyon Influential?

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According to Wikipedia, Cynthia Jane Kenyon is an American molecular biologist and biogerontologist known for her genetic dissection of aging in a widely used model organism, the roundworm Caenorhabditis elegans. She is the vice president of aging research at Calico Research Labs, and emeritus professor of biochemistry and biophysics at the University of California, San Francisco .

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Cynthia Kenyon's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A C. elegans mutant that lives twice as long as wild type (1993) (3119)
The genetics of ageing (2010) (2446)
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans (2003) (2118)
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. (1997) (1501)
Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor (2003) (1407)
Genetic pathways that regulate ageing in model organisms (2000) (1318)
The Plasticity of Aging: Insights from Long-Lived Mutants (2005) (1315)
The nematode Caenorhabditis elegans. (1988) (1199)
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling (2001) (1017)
Rates of Behavior and Aging Specified by Mitochondrial Function During Development (2002) (977)
Signals from the reproductive system regulate the lifespan of C. elegans (1999) (912)
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans (2007) (819)
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. (2002) (774)
Tissue-Specific Activities of C. elegans DAF-16 in the Regulation of Lifespan (2003) (737)
A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans (2008) (705)
Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans (2010) (558)
Regulation of lifespan by sensory perception in Caenorhabditis elegans (1999) (526)
New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen (2005) (506)
A Conserved Regulatory System for Aging (2001) (503)
Regulation of Life-Span by Germ-Line Stem Cells in Caenorhabditis elegans (2002) (485)
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. (1980) (481)
Timing Requirements for Insulin/IGF-1 Signaling in C. elegans (2002) (464)
Interventions to Slow Aging in Humans: Are We Ready? (2015) (462)
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging (2004) (455)
Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity (2010) (445)
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. (1995) (442)
Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of Diapause and Life Span (1998) (354)
Regulation of C. elegans Longevity by Specific Gustatory and Olfactory Neurons (2004) (344)
A homeotic gene cluster patterns the anteroposterior body axis of C. elegans (1993) (323)
A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans (1995) (321)
Germ-Cell Loss Extends C. elegans Life Span through Regulation of DAF-16 by kri-1 and Lipophilic-Hormone Signaling (2006) (309)
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. (2009) (304)
The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing (2011) (298)
Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli. (1981) (269)
The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development. (1998) (265)
A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. (1999) (260)
Role of a New Rho Family Member in Cell Migration and Axon Guidance in C. elegans (1997) (258)
A gene involved in the development of the posterior body region of C. elegans (1986) (242)
Mutations That Increase the Life Span of C. elegans Inhibit Tumor Growth (2006) (231)
Spatial and Temporal Controls Target pal-1 Blastomere-Specification Activity to a Single Blastomere Lineage in C. elegans Embryos (1996) (216)
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity (2010) (215)
Characterization of beta pat-3 heterodimers, a family of essential integrin receptors in C. elegans (1995) (212)
Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning. (1998) (184)
Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position. (1996) (180)
A Wnt signaling system that specifies two patterns of cell migration in C. elegans. (1999) (178)
Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of migration (1992) (177)
Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans (2007) (175)
The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling. (1998) (173)
Expression of the E. coli uvrA gene is inducible (1981) (173)
Healthy Animals with Extreme Longevity (2003) (173)
Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators. (2013) (172)
A pathway that links reproductive status to lifespan in Caenorhabditis elegans (2010) (165)
DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans (2007) (160)
A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans (2009) (155)
Spontaneous Age-Related Neurite Branching in Caenorhabditis elegans (2011) (148)
New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals (2012) (127)
Multiple HOM-C gene interactions specify cell fates in the nematode central nervous system. (1993) (126)
Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex (2007) (122)
The Two Isoforms of the Caenorhabditis elegans Leukocyte-Common Antigen Related Receptor Tyrosine Phosphatase PTP-3 Function Independently in Axon Guidance and Synapse Formation (2005) (117)
If birds can fly, why can't we? Homeotic genes and evolution (1994) (113)
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells (2011) (113)
A Transcription Elongation Factor That Links Signals from the Reproductive System to Lifespan Extension in Caenorhabditis elegans (2009) (112)
A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis. (1996) (112)
Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox (1988) (110)
Identification of genes from pattern formation, tyrosine kinase, and potassium channel families by DNA amplification. (1989) (106)
A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (2017) (102)
Establishment of left/right asymmetry in neuroblast migration by UNC-40/DCC, UNC-73/Trio and DPY-19 proteins in C. elegans. (2000) (101)
Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans (2009) (95)
Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans (2016) (95)
Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans (2009) (93)
A cluster of Antennapedia-class homeobox genes in a nonsegmented animal. (1991) (92)
The Somatic Reproductive Tissues of C. elegans Promote Longevity through Steroid Hormone Signaling (2010) (90)
How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude. (2017) (81)
Deep Proteome Analysis Identifies Age-Related Processes in C. elegans (2016) (81)
Genes affecting sensitivity to serotonin in Caenorhabditis elegans. (1996) (81)
EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans. (1999) (80)
Identification of genes that regulate a left-right asymmetric neuronal migration in Caenorhabditis elegans. (2003) (78)
MIG-13 Positions Migrating Cells along the Anteroposterior Body Axis of C. elegans (1999) (77)
The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans (2013) (74)
Caenorhabditis elegans integrates food and reproductive signals in lifespan determination (2007) (71)
The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans. (1997) (71)
Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system (1991) (70)
Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling. (1999) (68)
Selective silencing of cell communication influences anteroposterior pattern formation in C. elegans (1990) (68)
A steroid hormone that extends the lifespan of Caenorhabditis elegans (2007) (65)
Distinct Activities of the Germline and Somatic Reproductive Tissues in the Regulation of Caenorhabditis elegans' Longevity (2008) (65)
Patterning C. elegans: homeotic cluster genes, cell fates and cell migrations. (1994) (64)
The dance of the Hox genes: patterning the anteroposterior body axis of Caenorhabditis elegans. (1997) (60)
egl-27 generates anteroposterior patterns of cell fusion in C. elegans by regulating Hox gene expression and Hox protein function. (1999) (60)
Ponce d'elegans: Genetic Quest for the Fountain of Youth (1996) (57)
Regulation of damage-inducible genes in Escherichia coli. (1982) (56)
A perfect vulva every time: Gradients and signaling cascades in C. elegans (1995) (54)
Stimulation of Movement in a Quiescent, Hibernation-Like Form of Caenorhabditis elegans by Dopamine Signaling (2009) (53)
Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans. (2016) (52)
Cell contact regulates neuroblast formation in the Caenorhabditis elegans lateral epidermis. (1994) (51)
Specification of anteroposterior cell fates in Caenorhabditis elegans by Drosophila Hox proteins (1995) (50)
Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans. (2000) (50)
The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development (2005) (47)
Environmental Factors and Gene Activities That Influence Life Span (1997) (46)
REF-1, a protein with two bHLH domains, alters the pattern of cell fusion in C. elegans by regulating Hox protein activity. (2001) (45)
Expression of the homeotic gene mab-5 during Caenorhabditis elegans embryogenesis. (1992) (45)
Isolation of actin‐associated proteins from Caenorhabditis elegans oocytes and their localization in the early embryo (1997) (44)
Correct Hox gene expression established independently of position in Caenorhabditis elegans (1996) (44)
The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole‐rat biology (2021) (42)
The zinc finger protein REF-2 functions with the Hox genes to inhibit cell fusion in the ventral epidermis of C. elegans. (2002) (42)
Impact papers on aging in 2009 (2010) (40)
Two wnt genes in Caenorhabditis elegans. (1993) (39)
A Shift to Organismal Stress Resistance in Programmed Cell Death Mutants (2013) (36)
The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts. (2012) (32)
Analysis of mRNA synthesis following induction of the Escherichia coli SOS system. (1984) (30)
Micro‐proteomics with iterative data analysis: Proteome analysis in C. elegans at the single worm level (2016) (27)
Genes That Act Downstream of Sensory Neurons to Influence Longevity, Dauer Formation, and Pathogen Responses in Caenorhabditis elegans (2012) (26)
X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation. (2019) (26)
The bacterial response to DNA damage (1983) (24)
Cell signals allow the expression of a pre-existent neural pattern in C. elegans. (1992) (24)
Enrichment of regulatory motifs upstream of predicted DAF-16 targets (2006) (24)
Pediatric emergency care capacity in a low-resource setting: An assessment of district hospitals in Rwanda (2017) (22)
The genetics of ageing (2010) (21)
A Role for Autophagy Genes in the Extension of Lifespan by Dietary Restriction in C. elegans (2005) (21)
Some signal developments (1990) (21)
Regulation and functions of Escherichia coli genes induced by DNA damage. (1982) (20)
Correlates of Performance of Healthcare Workers in Emergency, Triage, Assessment and Treatment plus Admission Care (ETAT+) Course in Rwanda: Context Matters (2016) (20)
Cell lineage and the control of Caenorhabditis elegans development (1985) (19)
Mutagenesis and other responses induced by DNA damage in Escherichia coli. (1982) (18)
Developing Workforce Capacity in Public Health Informatics: Core Competencies and Curriculum Design (2018) (16)
Novel insights from a multiomics dissection of the Hayflick limit (2022) (13)
Regulation and function of cellular gene products involved in UV and chemical mutagenesis in E. coli. (1983) (11)
Impact papers on aging in 2009 - eScholarship (2010) (11)
Ras proteins. Some signal developments. (1990) (11)
Split-wrmScarlet and split-sfGFP: tools for faster, easier fluorescent labeling of endogenous proteins in Caenorhabditis elegans (2020) (10)
Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans’ Gene Expression Data (2020) (9)
Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan (2019) (9)
Partial reprogramming restores youthful gene expression through transient suppression of cell identity (2021) (9)
Mutagenesis and cellular responses to DNA damage. (1982) (7)
Cellular dialogs during development (1989) (7)
The complete cell atlas of an aging multicellular organism (2022) (7)
Could a hormone point the way to life extension? (2012) (6)
Developmental Timekeeping: Marking time with antisense (1994) (6)
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. 1980. (2005) (6)
My adventures with genes from the fountain of youth. (2004) (6)
Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity. (2022) (6)
Developing and implementing a novel mentorship model (4+ 1) for maternal, newborn and child health in Rwanda (2020) (6)
A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage (2020) (6)
Pattern, symmetry and surprises in the development of Caenorhabditis elegans (1983) (4)
Sydney Brenner (1927–2019) (2019) (3)
The mTOR Target S6 Kinase Arrests Development in Caenorhabditis elegans When the Heat-Shock Transcription Factor Is Impaired (2018) (3)
Addendum: A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (2020) (3)
The C. elegans Observatory: High-throughput exploration of behavioral aging (2022) (3)
Myeloperoxidase, a Leukocyte-Derived Vascular (2002) (3)
Inducibility ofageneproduct required forUV andchemical mutagenesis inEscherichia coli (1981) (3)
Impact of a Multifaceted Intervention to Improve Emergency Care on Newborn and Child Health Outcomes in Rwanda. (2021) (3)
A Conserved Regulatory System Minireview for Aging (2001) (2)
Developing and implementing a model of equitable distribution of mentorship in districts with spatial inequities and maldistribution of human resources for maternal and newborn care in Rwanda (2021) (2)
Revisiting the Hayflick Limit: Insights from an Integrated Analysis of Changing Transcripts, Proteins, Metabolites and Chromatin (2021) (2)
Reframed teacher leadership: A narrative inquiry (2008) (2)
Regulation of Longevity by Insulin/Igf-1 Signaling, Sensory Neurons and the Germline in the Nematode C. Elegans (2001) (2)
Sexist ads (1986) (1)
Mentors’ perspectives on strengths and weaknesses of a novel clinical mentorship programme in Rwanda: a qualitative study (2021) (1)
QnAs with Cynthia Kenyon. (2011) (1)
A Genetic Control Circuit for Aging (2011) (1)
Silencing the ASI gustatory neuron pair extends lifespan (2018) (1)
REGULATION AND FUNCTIONS OF Escherichia coli GENES (1982) (0)
MY FAVOURITE PAPER (2005) (0)
FOX-O and Aging across Organisms (2010) (0)
Inferring weighted gene annotations from expression data (2016) (0)
A Well-Studied Worm: The Nematode Caenorhabditis elegans. (1989) (0)
In Brief (2006) (0)
The 2002 Genetics Society of America Medal Andrew Fire (2003) (0)
A genetic screen identifies processes that couple oocyte maturation to proteostasis in the immortal C. elegans germ lineage (2020) (0)
Long-Lived Worms (2002) (0)
Genes From the Fountain of Youth (2008) (0)
Rescue of a developmental arrest caused by a C. elegans heat-shock transcription-factor mutation by loss of ribosomal S6-kinase activity (2018) (0)
A resource for analyzing C. elegans’ gene expression data using transcriptional gene modules and module-weighted annotations (2019) (0)
K Faculty (2017) (0)
Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of movement (1992) (0)
Step by step guide to tag endogenous genes with split-wrmScarlet and/or split-sfGFP in C. elegans v2 (2022) (0)
Angiotensinogen; the key to programming female hypertension? (2003) (0)
Step by step guide to tag endogenous genes with split-wrmScarlet and/or split-sfGFP in C. elegans v1 (2019) (0)
Heterochronic mutations of Caenorhabditis elegans their developmental and evolutionary significance (1985) (0)
Effects of glucose feeding on C. elegans lifespan and its implication in metabolic syndrome (2009) (0)
Thehomeoboxgene Phox 2 b is essential for the developmentof autonomic neural crest derivatives (1999) (0)
(din gene/recA/lexA regulation/operon fusion/SOS functions/uvrA) (0)
Silencing the ASI gustatory neuron pair increases expression of the stress-resistance gene sod-3 in a daf-16 and daf-3 independent manner (2018) (0)
pathway for ageing The first long-lived mutants : discovery of the insulin / IGF-1 (2010) (0)
Contents: Proteomics 3'16. (2016) (0)
Regulation de l'expression genetique conditionnelle par arn interference (2003) (0)
Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules that Affect Aging Pathways and Extend C. elegans’ Lifespan (2019) (0)

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