Anthony A. Kossiakoff

Anthony A. Kossiakoff's AcademicInfluence.com Rankings

Physics

#7778

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#9832

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Biophysics

#340

World Rank

#352

Historical Rank

physics Degrees

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Physics

Anthony A. Kossiakoff's Degrees

PhD Biophysics University of California, Berkeley
Masters Biophysics University of California, Berkeley
Bachelors Physics University of California, Berkeley

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Anthony A. Kossiakoff's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. (1992) (2076)
Visualization of arrestin recruitment by a G Protein-Coupled Receptor (2014) (421)
Structure of active β-arrestin1 bound to a G protein-coupled receptor phosphopeptide (2013) (367)
The X-ray structure of a growth hormoneprolactin receptor complex (1994) (360)
High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries. (2007) (315)
Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin. (1981) (233)
Crystal structure of full-length KcsA in its closed conformation (2009) (223)
Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain (2013) (211)
X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers. (2008) (200)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (191)
X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. (1993) (180)
Protein dynamics investigated by the neutron diffraction–hydrogen exchange technique (1982) (159)
The crystallographically determined structures of atypical strained disulfides engineered into subtilisin. (1986) (157)
The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation. (1991) (149)
Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of alzheimer's amyloid β‐protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specificities (1997) (131)
Comprehensive and Quantitative Mapping of Energy Landscapes for Protein-Protein Interactions by Rapid Combinatorial Scanning*♦ (2006) (119)
The crystal structure of a quercetin 2,3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site(s). (2005) (119)
Neutron diffraction identifies His 57 as the catalytic base in trypsin (1980) (116)
X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants. (1991) (116)
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. (2006) (114)
Synthetic antibodies for specific recognition and crystallization of structured RNA (2008) (111)
The crystal structure of affinity-matured human growth hormone at 2 A resolution. (1994) (109)
Architecture of the fungal nuclear pore inner ring complex (2015) (106)
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation (2015) (104)
X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor. (1990) (102)
Structure of the Get3 targeting factor in complex with its membrane protein cargo (2015) (97)
Total chemical synthesis and X-ray crystal structure of a protein diastereomer: [D-Gln 35]ubiquitin. (2005) (95)
Solvent structure in crystals of trypsin determined by X‐ray and neutron diffraction (1992) (92)
Architecture of the nuclear pore complex coat (2015) (92)
Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT (2019) (88)
Generating conformation-specific synthetic antibodies to trap proteins in selected functional states. (2013) (88)
A High Through-put Platform for Recombinant Antibodies to Folded Proteins* (2015) (87)
Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A. (1990) (86)
Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. (1992) (85)
Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor (2000) (81)
Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors (1994) (79)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme (2018) (74)
Toward chaperone‐assisted crystallography: Protein engineering enhancement of crystal packing and X‐ray phasing capabilities of a camelid single‐domain antibody (VHH) scaffold (2008) (71)
Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope. (2007) (71)
Racemic crystallography of synthetic protein enantiomers used to determine the X‐ray structure of plectasin by direct methods (2009) (69)
Variability of conformations at crystal contacts in BPTI represent true low‐energy structures: Correspondence among lattice packing and molecular dynamics structures (1992) (68)
Mechanism of activation gating in the full-length KcsA K+ channel (2011) (66)
Analysis of solvent structure in proteins using neutron D2OH2O solvent maps: Pattern of primary and secondary hydration of trypsin (1992) (65)
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation. (2014) (64)
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination (2010) (63)
Allosteric Control of Ligand Binding Affinity Using Engineered Conformation-Specific Effector Proteins (2010) (60)
A YidC-like Protein in the Archaeal Plasma Membrane. (2015) (59)
Crystals of the complex between human growth hormone and the extracellular domain of its receptor. (1991) (57)
The application of neutron crystallography to the study of dynamic and and hydration properties of proteins. (1985) (57)
Dissecting the energetics of protein α-helix C-cap termination through chemical protein synthesis (2006) (55)
Structural basis for cytokine hormone-receptor recognition and receptor activation. (1998) (54)
Exploring and designing protein function with restricted diversity. (2007) (53)
Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. (2016) (50)
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1 (2021) (50)
Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity. (2000) (46)
Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization (2003) (45)
The Structure and Activity of a Monomeric Interferon-γ:α-Chain Receptor Signaling Complex (2001) (43)
An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells (2009) (43)
Site2 binding energetics of the regulatory step of growth hormone–induced receptor homodimerization (2003) (42)
The structural basis for biological signaling, regulation, and specificity in the growth hormone-prolactin system of hormones and receptors. (2004) (41)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. (2017) (40)
Phage display selections for affinity reagents to membrane proteins in nanodiscs. (2015) (40)
Shotgun Alanine Scanning Shows That Growth Hormone Can Bind Productively to Its Receptor through a Drastically Minimized Interface* (2005) (39)
Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins (2020) (38)
X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods. (2009) (38)
Structural effects induced by mutagenesis affected by crystal packing factors: The structure of a 30–51 disulfide mutant of basic pancreatic trypsin inhibitor (1992) (38)
Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis (2005) (37)
The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry. (2006) (37)
The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity. (2003) (37)
The production and X-ray structure determination of perdeuterated Staphylococcal nuclease. (1994) (36)
Neutron protein crystallography: advances in methods and applications. (1983) (35)
Structural basis for activation of voltage sensor domains in an ion channel TPC1 (2018) (35)
Crystal structure of subtilisin BPN′ variants containing disulfide bonds and cavities: Concerted structural rearrangements induced by mutagenesis (1990) (34)
Structure and mechanism of the ER-based glucosyltransferase ALG6 (2020) (33)
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling (2020) (32)
The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled. (2004) (32)
X-ray structure of human relaxin at 1·5Å (1991) (32)
Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2 (2018) (31)
Deciphering the role of the electrostatic interactions involving Gly70 in eglin C by total chemical protein synthesis. (2000) (31)
Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling (2015) (31)
Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces. (2008) (30)
Scalable high throughput selection from phage-displayed synthetic antibody libraries. (2015) (29)
Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites. (2002) (28)
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins (2015) (27)
Crystal structure and site 1 binding energetics of human placental lactogen. (2006) (27)
Structural basis of omega-3 fatty acid transport across the blood–brain barrier (2021) (27)
Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries. (2004) (27)
Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones. (2002) (27)
Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis. (2005) (26)
Architecture of the cytoplasmic face of the nuclear pore (2021) (26)
The 1.38 Å crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway (2008) (25)
Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes. (1999) (25)
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. (2014) (25)
Hydroxyl hydrogen conformations in trypsin determined by the neutron diffraction solvent difference map method: relative importance of steric and electrostatic factors in defining hydrogen-bonding geometries. (1990) (24)
High affinity RNase S-peptide variants obtained by phage display have a novel "hot-spot" of binding energy. (2001) (22)
The 2.0 A structure of bovine interferon-gamma; assessment of the structural differences between species. (2000) (21)
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle (2020) (20)
Principal determinants leading to transition state formation of a protein–protein complex, orientation trumps side-chain interactions (2009) (20)
Effect of protein packing structure on side-chain methyl rotor conformations (1984) (18)
An automated peak fitting procedure for processing protein diffraction data from a linear position‐sensitive detector (1980) (18)
Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins (2018) (18)
A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction. (2015) (18)
Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor. (1998) (17)
Neutron structure of subtilisin BPN': effects of chemical environment on hydrogen-bonding geometries and the pattern of hydrogen-deuterium exchange in secondary structure elements. (1991) (16)
Structure of an AMPK complex in an inactive, ATP-bound state (2021) (15)
The Neutron Structure of the Hydrophobic Plant Protein Crambin (1982) (15)
Generating Conformation and Complex-Specific Synthetic Antibodies. (2017) (15)
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM. (2019) (15)
A comparison of neutron diffraction and molecular dynamics structures: hydroxyl group and water molecule orientations in trypsin. (1995) (15)
Receptor action and interaction (1992) (14)
Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide. (2009) (14)
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins (2021) (13)
Protein dynamics investigated by neutron diffraction. (1986) (13)
The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold (2005) (13)
Structures of ABCB4 provide insight into phosphatidylcholine translocation (2021) (12)
Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin. (1988) (11)
The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex. (2001) (11)
Structural basis of lipopolysaccharide maturation by the O-antigen ligase (2022) (10)
A polar ring endows improved specificity to an antibody fragment (2016) (10)
Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. (2016) (10)
Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo. (2012) (9)
Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure (2010) (8)
Structure of bistramide A-actin complex at a 1.35 angstroms resolution. (2006) (8)
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel (2022) (8)
Engineered Ultra-High Affinity Synthetic Antibodies for SARS-CoV-2 Neutralization and Detection (2021) (8)
Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin. (2015) (8)
Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity. (2017) (8)
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver (2022) (8)
Probing the Functions of the Paramyxovirus Glycoproteins F and HN with a Panel of Synthetic Antibodies (2014) (8)
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias (2022) (8)
The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. (2018) (8)
A method of solvent structure analysis for proteins using D2O-H2O neutron difference maps. (1986) (7)
Molecular recognition in biological systems: from activation to inhibition. (1993) (7)
Structure of the growth hormone-receptor complex and mechanism of receptor signaling. (1995) (7)
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers (2022) (6)
New Tricks for an Old Dimer (2014) (6)
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin. (2019) (5)
The first semi-synthetic serine protease made by native chemical ligation. (2003) (5)
Architecture of the nuclear pore inner ring complex (2016) (5)
Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody (2017) (4)
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical. (2016) (4)
An engineered ultra‐high affinity Fab‐Protein G pair enables a modular antibody platform with multifunctional capability (2020) (4)
Structural consequences of mutation. (1992) (4)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment. (2020) (3)
Crystal structure of YxaG, a dioxygenase from Bacillus subtilis (2005) (3)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (3)
Protein engineering. Editorial overview (1993) (3)
CryoEM Structures of the Human HIV-1 Restriction Factor SERINC3 and Function as a Lipid Transporter (2022) (3)
X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution. (2006) (3)
Structural Insights into Phospholipase Cε (2022) (3)
X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin (2005) (2)
Crystal Structure of the Snow Flea Antifreeze Protein (2008) (2)
X-ray Crystal Structure of a Chemically Synthesized Ubiquitin (2005) (2)
Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder (2022) (2)
assessment of the structural differences between species (2000) (2)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits (2021) (2)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody That Targets Two Distinct Epitopes on αv Integrins. (2021) (1)
Advances in Methods and Applications (1983) (1)
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase (2023) (1)
Targeting a proteolytic neo-epitope of CUB-domain containing protein 1 in RAS-driven cancer (2021) (1)
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes (2022) (1)
Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum. (2023) (1)
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels (2022) (1)
Growth Hormone and Prolactin Family of Hormones and Receptors: The Structural Basis for Receptor Activation and Regulation (2003) (1)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (1)
PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR (2002) (1)
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin (2017) (0)
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform (2019) (0)
Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) (2018) (0)
BASIC PANCREATIC TRYPSIN INHIBITOR (MET 52 OXIDIZED) (1992) (0)
Keeping signaling in check. (2010) (0)
Structural Insights into PLCε: Discovery of an Integrated RA1 Domain and Novel Regulatory Elements (2021) (0)
Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 1 (2018) (0)
Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab (2020) (0)
Probing the functions of the paramyxovirus glycoproteins F and HN 3 with a panel of synthetic antibodies ( sABs ) 4 5 (2014) (0)
Interaction Landscape of K29-Linked Ubiquitin Signaling Revealed by a Linkage-Specific Synthetic Antigen-Binding Fragment (2020) (0)
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.1A resolution: SE5B-ORTHO-1 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. (2008) (0)
Snow Flea Antifreeze Protein Racemate (2008) (0)
Cryo-EM structure of human insulin degrading enzyme in complex with insulin (2017) (0)
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB) (2011) (0)
Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment (2016) (0)
Structural determination of an protein complex of a Fab with increased solubility (2016) (0)
Supplementary Materials for Architecture of the nuclear pore complex coat (2015) (0)
Generation of Synthetic Antibody Fragments to Detergent Solubilized Membrane Proteins (2017) (0)
X-ray Crystal Structure of L-Plectasin (2009) (0)
Crystal structure of human paxillin LD4 motif in complex with Fab fragment (2015) (0)
Crystal Structure Of Full-length Kcsa Trapped In Open Conformation Reveals That C-terminal Domain Fine Tunes Activation And Coupled Inactivation (2009) (0)
Crystal structure of Chaetomium thermophilum Nup188 TAIL domain (2015) (0)
Rhodopsin-Gi complex (2018) (0)
BOVINE CHYMOTRYPSIN COMPLEXED TO APPI (1997) (0)
Structure of antigen-Fab 12E complex with Histone chaperone ASF1 (2018) (0)
Structure of the yeast coat nucleoporin complex, space group P212121 (2015) (0)
The structural consequences of site-directed mutations (1987) (0)
Hydroxyl and water molecule orientations in trypsin: comparison to molecular dynamic structures. (1994) (0)
The D2O structure of crambin by neutron diffraction at 1.5 Å (1984) (0)
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel (2022) (0)
Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment (2018) (0)
Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2 (2018) (0)
Structure of antigen-Fab complex with engineered switch residue region. (2017) (0)
Crystal Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583 at 2.4 A Resolution, Probable N-Acyltransferase (2006) (0)
Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site (2015) (0)
Crystal structure of Chaetomium thermophilum Nup192 TAIL domain (2015) (0)
BOVINE INTERFERON-GAMMA AT 2.0 ANGSTROMS (1999) (0)
Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy (2013) (0)
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5 (2020) (0)
The Role of Molecular Recognition in Activation and Regulation in the Growth Hormone-Prolactin Family of Hormones and Receptors (1998) (0)
X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin with a Cubic Space Group (2006) (0)
Synthetic Antigen Binders: Novel applications for Structural and Cell Biology (2011) (0)
, Zachary with a Panel of Synthetic Antibodies Paramyxovirus Glycoproteins F and HN Probing the Functions of the (2014) (0)
X-ray Crystal Structure of Chemically Synthesized Crambin-{alpha}carboxamide (2007) (0)
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline (2020) (0)
Structural basis of lipopolysaccharide maturation by the O-antigen ligase (2022) (0)
The crystal structure of the cytoplasmic domain of KcsA (2009) (0)
Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling (2015) (0)
BOVINE TRYPSIN COMPLEXED TO APPI (1997) (0)
High resolution structure of a specific synthetic FAB bound to P4-P6 RNA ribozyme domain (2007) (0)
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain (2018) (0)
Molecular Modeling and Simulations of the Transmembrane Domain of Human Growth Hormone Receptor (2010) (0)
A T cell redirection platform for co-targeting dual antigens on solid tumors (2021) (0)
Visualizing Conformational Changes of the Magnesium Channel Cora using Synthetic Antibodies (2020) (0)
Structural basis for CorA channel gating using conformation-specific synthetic antigen binders and single-particle cryo-EM. (2023) (0)
Cryo-EM structures of human claudin-4 in complex with its bacterial toxin antagonist enabled by synthetic antibody fragments reveal targeting mechanisms and therapeutic potential (2022) (0)
Synthetic Antibody Binders Detect Distinct Cellular States of Chromosome Passenger Complex Proteins (2022) (0)
Author response: Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling (2020) (0)
2.4A X-ray structure of Urocanase protein complexed with NAD (2004) (0)
Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias (2022) (0)
Neutron crystallography: methods and information content (2006) (0)
Using synthetic affinity binders (sABs) as biological tools to study the chromosome passenger complex proteins (2015) (0)
BOVINE INTERFERON-GAMMA AT 2.9 ANGSTROMS (1999) (0)
3.1 A X-ray structure of putative Oligoendopeptidase F: Crystals grown by microfluidic seeding (2006) (0)
Probing and Designing Growth Hormone-Receptor Interactions (1995) (0)
Validation of Recombinant Antibodies Against Human Transcription Factors (2015) (0)
Crystal structure of an engineered ultra-high affinity Fab-Protein G complex (2019) (0)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (0)
Structure and mechanism of the ER-based glucosyltransferase ALG6 (2020) (0)
Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc (2020) (0)
Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins (2020) (0)
Dynamical properties of proteins by hydrogen exchange and neutron diffraction (1981) (0)
CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR (2000) (0)
The structural basis for activation of voltage sensor domains in an ion channel TPC1 (2018) (0)
X-ray Crystal Structure of Chemically Synthesized Crambin (2007) (0)
Atomic structure of a putative anaerobic dehydrogenase component (2004) (0)
Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody (2017) (0)
2.3A crystal structure of phospho-beta-glucosidase (2004) (0)
The crystal structure of hypothetical UPF0244 protein yjjX at resolution 1.68 Angstrom (2004) (0)
1:1 COMPLEX BETWEEN AN INTERFERON GAMMA SINGLE-CHAIN VARIANT AND ITS RECEPTOR (2000) (0)
Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels (2022) (0)
Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment (2010) (0)
1.7 A Crystal Structure of Protein of Unknown Function SA2161 from Meticillin-Resistant Staphylococcus aureus, Probable Acetyltransferase (2005) (0)
Structure of Get3 bound to the transmembrane domain of Pep12 (2015) (0)
1.9A crystal structure of protein AQ328 from Aquifex aeolicus (2004) (0)
Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution: native mono_1 crystal form (2007) (0)
Structure of the rhodopsin–rhodopsin kinase complex defines the rules of engagement between G protein‐coupled receptors (GPCRs) and GPCR kinases (2021) (0)
Synthetic antibody binders detect distinct cellular states of Chromosome Passenger Complex proteins. (2022) (0)
Crystal structure of human paxillin LD2 motif in complex with Fab fragment (2015) (0)
Author response: Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme (2018) (0)
3.0 A X-ray structure of putative oligoendopeptidase F: crystals grown by vapor diffusion technique (2006) (0)
Cryo-EM structure of human insulin degrading enzyme (2017) (0)
Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex (2015) (0)
Generation of a De Novo Actin Pointed-End Binding Protein (2010) (0)
Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody (2018) (0)
Crystal Structure of Human Placental Lactogen (2006) (0)
Abstract SY06-01: Intracellular antibody therapy: Specific delivery of synthetic antibodies to cytoplasmic targets in cancer cells (2012) (0)
Reply to Kang and Brooks: Comment on the calculations in protein thermodynamics (2018) (0)
Crystal Structure of a Protein of Unknown Function AQ1966 from Aquifex aeolicus VF5 (2005) (0)
Use of Synthetic Antibodies Targeted to the Jak/Stat Pathway in Breast Cancer (2010) (0)
BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI (1997) (0)
X-ray Crystal Structure of Racemic Plectasin (2009) (0)
Automated peak fitting procedure for processing data from an area detector and its application to the neutron structure of trypsin. (1985) (0)
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT (2019) (0)
Association of Thromboxane A2 Receptor with Endoplasmic Reticulum-Membrane Spanning Proteins (2013) (0)
Snow Flea Antifreeze Protein Quasi-racemate (2008) (0)
Structural studies of an ecotin variant (2000) (0)
Hydroxyl and Water Molecule Orientations in Trypsin (1996) (0)
Crystal structure of BRIL bound to an affinity matured synthetic antibody. (2019) (0)
Xray structure of scorpion toxin BmBKTx1 (2009) (0)
Crystal structure of Asf1-Fab 12E complex (2018) (0)
CONTROLLING CONFORMATIONAL DYNAMICS TO MODULATE PROTEIN FUNCTION (2013) (0)

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What Schools Are Affiliated With Anthony A. Kossiakoff?

Anthony A. Kossiakoff is affiliated with the following schools:

University of California, Berkeley
University of Delaware
University of Chicago
Johns Hopkins University
University of California, San Francisco
Davis & Elkins College

Anthony A. Kossiakoff's Academic­Influence.com Rankings