Farshid Guilak
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American engineer and orthopedist
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Farshid Guilak's Degrees
- Bachelors Mechanical Engineering University of California, Berkeley
- Masters Mechanical Engineering Stanford University
- PhD Mechanical Engineering Stanford University
- Masters Medicine Stanford University
Why Is Farshid Guilak Influential?
(Suggest an Edit or Addition)According to Wikipedia, Farshid Guilak is an American engineer and orthopedic researcher. He is the Mildred B. Simon Professor of Orthopaedic Surgery at Washington University in St. Louis and director of research at Shriners Hospitals for Children. He is also on the faculty of the departments of Biomedical Engineering, Mechanical Engineering & Materials Science, and Developmental Biology at Washington University.
Farshid Guilak's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Control of stem cell fate by physical interactions with the extracellular matrix. (2009) (1735)
- Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. (2003) (1120)
- RNA-guided gene activation by CRISPR-Cas9-based transcription factors (2013) (1116)
- Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds. (2004) (794)
- 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures (2015) (736)
- Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo. (2002) (686)
- A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. (2007) (660)
- Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. (2010) (642)
- Functional tissue engineering: the role of biomechanics. (2000) (636)
- Post‐traumatic osteoarthritis: Improved understanding and opportunities for early intervention (2011) (555)
- Viscoelastic properties of the cell nucleus. (2000) (548)
- Clonal analysis of the differentiation potential of human adipose‐derived adult stem cells (2006) (502)
- Chondrocyte deformation and local tissue strain in articular cartilage: A confocal microscopy study (1995) (500)
- The mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions in articular cartilage. (2000) (475)
- Biomechanical factors in osteoarthritis. (2011) (434)
- Multipotent Stromal Cells Derived From the Infrapatellar Fat Pad of the Knee (2003) (419)
- Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype (2010) (406)
- The Role of Mechanical Loading in the Onset and Progression of Osteoarthritis (2005) (405)
- Compression-induced changes in the shape and volume of the chondrocyte nucleus. (1995) (400)
- Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration. (1999) (371)
- Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis (1994) (342)
- TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading (2014) (342)
- Tissue engineering for articular cartilage repair--the state of the art. (2013) (338)
- The Pericellular Matrix as a Transducer of Biomechanical and Biochemical Signals in Articular Cartilage (2006) (336)
- Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes. (2008) (336)
- Viscoelastic properties of zonal articular chondrocytes measured by atomic force microscopy. (2006) (317)
- The role of biomechanics and inflammation in cartilage injury and repair. (2004) (310)
- Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage. (1999) (301)
- Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. (2006) (300)
- A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential? (2007) (296)
- Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. (2006) (293)
- Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. (2006) (292)
- Differentiation potential of adipose derived adult stem (ADAS) cells. (2003) (273)
- Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix. (2009) (272)
- Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage (2014) (271)
- Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes. (2009) (270)
- The structure and function of the pericellular matrix of articular cartilage. (2014) (254)
- The effects of osmotic stress on the viscoelastic and physical properties of articular chondrocytes. (1999) (252)
- Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix. (2010) (249)
- Viscoelastic properties of chondrocytes from normal and osteoarthritic human cartilage (2000) (245)
- The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes. (2004) (242)
- The deformation behavior and mechanical properties of chondrocytes in articular cartilage. (1999) (242)
- Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells (2012) (241)
- Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells (2010) (240)
- Concise Review: Adipose‐Derived Stromal Vascular Fraction Cells and Stem Cells: Let's Not Get Lost in Translation (2011) (235)
- Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration. (2006) (235)
- Synergistic and tunable human gene activation by combinations of synthetic transcription factors (2013) (234)
- Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis. (2006) (234)
- Adipose-derived adult stem cells for cartilage tissue engineering. (2004) (231)
- Osteoarthritis as a disease of the cartilage pericellular matrix. (2018) (231)
- Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition. (1994) (228)
- The effects of matrix compression on proteoglycan metabolism in articular cartilage explants. (1994) (226)
- Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells (2005) (224)
- Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci. (2001) (222)
- The Mechanobiology of Articular Cartilage: Bearing the Burden of Osteoarthritis (2014) (220)
- Composite Three‐Dimensional Woven Scaffolds with Interpenetrating Network Hydrogels to Create Functional Synthetic Articular Cartilage (2013) (209)
- Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis. (2003) (204)
- Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise. (2012) (198)
- Functional tissue engineering: the role of biomechanics in articular cartilage repair. (2001) (194)
- Effects of Transforming Growth Factor β1 and Dexamethasone on the Growth and Chondrogenic Differentiation of Adipose-Derived Stromal Cells (2003) (193)
- Advanced Material Strategies for Tissue Engineering Scaffolds (2009) (193)
- Regional material properties of the human hip joint capsule ligaments (2001) (192)
- The biomechanical role of the chondrocyte pericellular matrix in articular cartilage. (2005) (191)
- Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis. (2009) (189)
- Biomechanics: Cell Research and Applications for the Next Decade (2009) (189)
- Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage. (2005) (184)
- Biomechanics and mechanobiology in functional tissue engineering. (2014) (183)
- Physical regulation of cartilage metabolism (2005) (179)
- Developmental and osteoarthritic changes in Col6a1-knockout mice: biomechanics of type VI collagen in the cartilage pericellular matrix. (2009) (178)
- Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage. (2007) (176)
- Mechanically induced calcium waves in articular chondrocytes are inhibited by gadolinium and amiloride (1999) (174)
- Site-Specific Molecular Diffusion in Articular Cartilage Measured using Fluorescence Recovery after Photobleaching (2003) (173)
- Joint degeneration following closed intraarticular fracture in the mouse knee: A model of posttraumatic arthritis (2007) (172)
- The mechanical properties of the human hip capsule ligaments. (2002) (171)
- Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee. (2011) (167)
- Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. (2010) (163)
- Functional Tissue Engineering (2001) (160)
- The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs. (2013) (157)
- The effects of static and intermittent compression on nitric oxide production in articular cartilage explants (2001) (156)
- Volume and surface area measurement of viable chondrocytes in situ using geometric modelling of serial confocal sections (1994) (156)
- Human adipose-derived cells: an update on the transition to clinical translation. (2012) (155)
- The deformation behavior and viscoelastic properties of chondrocytes in articular cartilage. (2000) (153)
- 2010 Nicolas Andry Award: Multipotent Adult Stem Cells from Adipose Tissue for Musculoskeletal Tissue Engineering (2010) (153)
- Mechanical regulation of chondrogenesis (2013) (149)
- Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering. (2015) (149)
- Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: A randomized controlled study (2012) (148)
- Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. (2004) (146)
- Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy (2000) (143)
- Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. (2008) (143)
- Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis (2014) (138)
- Mechanical signals as regulators of stem cell fate. (2004) (137)
- Spatial mapping of the biomechanical properties of the pericellular matrix of articular cartilage measured in situ via atomic force microscopy. (2010) (137)
- Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways. (2001) (136)
- Mechanical regulation of nuclear structure and function. (2012) (134)
- The effects of osmotic stress on the structure and function of the cell nucleus (2009) (134)
- Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen. (2006) (134)
- The Development of Posttraumatic Arthritis After Articular Fracture (2006) (134)
- Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice (2010) (134)
- Differentiation of the Bone-Tissue Remodeling Response to Axial and Torsional Loading in the Turkey Ulna*† (1996) (132)
- Biomechanical factors in tissue engineered meniscal repair. (1999) (131)
- Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4 (2010) (131)
- Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. (2015) (131)
- Incompressibility of the solid matrix of articular cartilage under high hydrostatic pressures. (1998) (130)
- Composite scaffolds for cartilage tissue engineering. (2008) (128)
- Zonal variations in the three-dimensional morphology of the chondron measured in situ using confocal microscopy. (2006) (128)
- Conformational mechanics, adsorption, and normal force interactions of lubricin and hyaluronic acid on model surfaces. (2008) (128)
- Functional properties of cell-seeded three-dimensionally woven poly(epsilon-caprolactone) scaffolds for cartilage tissue engineering. (2010) (126)
- Stem cell-based therapies for osteoarthritis: challenges and opportunities (2013) (124)
- Synovial fluid concentrations and relative potency of interleukin‐1 alpha and beta in cartilage and meniscus degradation (2013) (123)
- Intra-articular Delivery of Purified Mesenchymal Stem Cells from C57BL/6 or MRL/MpJ Superhealer Mice Prevents Posttraumatic Arthritis (2013) (122)
- Differentiation of adipose stem cells. (2008) (120)
- In vitro Differentiation Potential of Mesenchymal Stem Cells (2008) (120)
- Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis (1999) (119)
- Collagenase in the treatment of Dupuytren's disease: an in vitro study. (1996) (118)
- Viscoelastic properties of intervertebral disc cells. Identification of two biomechanically distinct cell populations. (1999) (118)
- Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage (2014) (116)
- Large Deformation Finite Element Analysis of Micropipette Aspiration to Determine the Mechanical Properties of the Chondrocyte (2005) (115)
- Extended passaging, but not aldehyde dehydrogenase activity, increases the chondrogenic potential of human adipose‐derived adult stem cells (2006) (114)
- Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury (2014) (113)
- Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage (2015) (113)
- Friction Force Microscopy of Lubricin and Hyaluronic Acid between Hydrophobic and Hydrophilic Surfaces. (2009) (112)
- In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(epsilon-caprolactone) scaffolds. (2010) (110)
- Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse. (2008) (110)
- Tendon mechanobiology: Current knowledge and future research opportunities (2015) (108)
- The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. (2003) (107)
- Diurnal variations in articular cartilage thickness and strain in the human knee. (2013) (106)
- Differential effects of static and dynamic compression on meniscal cell gene expression (2003) (106)
- Micromechanical mapping of early osteoarthritic changes in the pericellular matrix of human articular cartilage. (2013) (104)
- Effects of transforming growth factor beta1 and dexamethasone on the growth and chondrogenic differentiation of adipose-derived stromal cells. (2003) (104)
- Hypo-osmotic stress induces calcium-dependent actin reorganization in articular chondrocytes. (2003) (104)
- Zonal Uniformity in Mechanical Properties of the Chondrocyte Pericellular Matrix: Micropipette Aspiration of Canine Chondrons Isolated by Cartilage Homogenization (2005) (104)
- Temporomandibular joint pain: A critical role for Trpv4 in the trigeminal ganglion (2013) (102)
- Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model (2011) (102)
- Mechanobiology of the Meniscus (2015) (102)
- Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche. (2011) (101)
- Why is obesity associated with osteoarthritis? Insights from mouse models of obesity. (2008) (101)
- Fabrication of anatomically-shaped cartilage constructs using decellularized cartilage-derived matrix scaffolds. (2016) (100)
- Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. (2013) (100)
- Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model. (2006) (97)
- The Role of Macrophages in Osteoarthritis and Cartilage Repair. (2020) (97)
- Genipin-crosslinked cartilage-derived matrix as a scaffold for human adipose-derived stem cell chondrogenesis. (2013) (97)
- Circadian Oscillation of Gene Expression in Murine Calvarial Bone (2007) (96)
- Non-invasive mouse models of post-traumatic osteoarthritis. (2015) (95)
- Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis (2016) (95)
- Induction of cyclooxygenase-2 by mechanical stress through a nitric oxide-regulated pathway. (2002) (95)
- Multifunctional hybrid three-dimensionally woven scaffolds for cartilage tissue engineering. (2010) (94)
- Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia. (2005) (94)
- Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing (2016) (93)
- Multilayered electrospun scaffolds for tendon tissue engineering. (2013) (92)
- Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering. (2014) (91)
- Emerging roles for long noncoding RNAs in skeletal biology and disease (2017) (89)
- The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. (2005) (89)
- Transient receptor potential vanilloid 4 (2010) (89)
- Depth-dependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy. (2013) (88)
- Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice. (2012) (87)
- Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. (2014) (87)
- Regulation of matrix turnover in meniscal explants: role of mechanical stress, interleukin-1, and nitric oxide. (2003) (87)
- 3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures (Adv. Mater. 27/2015) (2015) (87)
- Diffusional anisotropy in collagenous tissues: fluorescence imaging of continuous point photobleaching. (2006) (86)
- Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice. (2013) (85)
- Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas‐Induced Apoptosis–Transgenic Mice (2017) (84)
- A biomechanical role for perlecan in the pericellular matrix of articular cartilage. (2012) (84)
- Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds. (2010) (83)
- Chondropathy after meniscal tear or partial meniscectomy in a canine model (2002) (83)
- Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha. (2007) (83)
- Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis (2000) (82)
- Inhibition of integrative repair of the meniscus following acute exposure to interleukin‐1 in vitro (2008) (82)
- Chondrocytes isolated from mature articular cartilage retain the capacity to form functional gap junctions (1995) (82)
- Stress, Strain, Pressure and Flow Fields in Articular Cartilage and Chondrocytes (1994) (81)
- Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet (2012) (80)
- Urea as a passive transport marker for arthritis biomarker studies. (2002) (80)
- Adjacent tissues (cartilage, bone) affect the functional integration of engineered calf cartilage in vitro. (2005) (78)
- Multiscale Mechanics of Articular Cartilage: Potentials and Challenges of Coupling Musculoskeletal, Joint, and Microscale Computational Models (2012) (78)
- Hyperosmotically induced volume change and calcium signaling in intervertebral disk cells: the role of the actin cytoskeleton. (2002) (78)
- The dynamic mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions under cyclic compressive loading. (2008) (77)
- Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice. (2005) (76)
- Monolayer cell expansion conditions affect the chondrogenic potential of adipose‐derived stem cells (2008) (75)
- The effect of dynamic mechanical compression on nitric oxide production in the meniscus. (2001) (75)
- Engineered cartilage using primary chondrocytes cultured in a porous cartilage-derived matrix. (2011) (75)
- Design of a free-floating polycarbonate-urethane meniscal implant using finite element modeling and experimental validation. (2010) (74)
- Repair Response of the Inner and Outer Regions of the Porcine Meniscus in Vitro (2007) (73)
- An axisymmetric boundary integral model for assessing elastic cell properties in the micropipette aspiration contact problem. (2002) (73)
- Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. (2015) (72)
- Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee (2002) (72)
- In situ friction measurement on murine cartilage by atomic force microscopy. (2008) (71)
- Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue, and infrapatellar fad pad: The effects of free fatty acids (2012) (71)
- High body mass index is associated with increased diurnal strains in the articular cartilage of the knee. (2013) (71)
- Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes. (2006) (71)
- In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity. (2015) (70)
- Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage. (2002) (70)
- Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. (2008) (68)
- Inhibition of Matrix Metalloproteinases Enhances In Vitro Repair of the Meniscus (2009) (68)
- Cell migration: implications for repair and regeneration in joint disease (2019) (67)
- TRPV4 as a therapeutic target for joint diseases (2015) (67)
- Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source. (2015) (66)
- Age‐associated increases in the size of the infrapatellar fat pad in knee osteoarthritis as measured by 3T MRI (2010) (66)
- A vision on the future of articular cartilage repair. (2014) (65)
- The Effects of Adipokines on Cartilage and Meniscus Catabolism (2011) (65)
- The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds. (2012) (64)
- Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis (2021) (64)
- Interleukin-1 and tumor necrosis factor alpha inhibit repair of the porcine meniscus in vitro. (2007) (64)
- An axisymmetric boundary integral model for incompressible linear viscoelasticity: application to the micropipette aspiration contact problem. (2000) (64)
- The Role of Cytokines in Posttraumatic Arthritis (2014) (63)
- Atomic force microscopy reveals regional variations in the micromechanical properties of the pericellular and extracellular matrices of the meniscus (2013) (63)
- Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma. (2007) (62)
- Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice. (2008) (62)
- Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs (2017) (61)
- Nonlinear Osmotic Properties of the Cell Nucleus (2009) (61)
- Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells. (2011) (61)
- The Role of F-Actin in Hypo-Osmotically Induced Cell Volume Change and Calcium Signaling in Anulus Fibrosus Cells (2004) (61)
- Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells (2018) (60)
- Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis (2021) (60)
- A method for quantifying cell size from differential interference contrast images: validation and application to osmotically stressed chondrocytes (2002) (59)
- Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1. (2010) (57)
- Therapeutic opportunities to prevent post‐traumatic arthritis: Lessons from the natural history of arthritis after articular fracture (2015) (57)
- Adipose tissue as a stem cell source for musculoskeletal regeneration. (2011) (56)
- International Expert Consensus on a Cell Therapy Communication Tool: DOSES (2019) (56)
- Integrative repair of the meniscus: lessons from in vitro studies. (2008) (56)
- Measurement of intracellular strain on deformable substrates with texture correlation. (2007) (55)
- Cartilage degeneration in post‐collapse cases of osteonecrosis of the human femoral head: Altered mechanical properties in tension, compression, and shear (2005) (55)
- Altered Trabecular Bone Structure and Delayed Cartilage Degeneration in the Knees of Collagen VI Null Mice (2012) (54)
- Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage (2012) (54)
- The relationship of self-reported pain and functional impairment to gait mechanics in overweight and obese persons with knee osteoarthritis. (2009) (54)
- Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation. (2014) (53)
- Regulation of Decellularized Tissue Remodeling via Scaffold-Mediated Lentiviral Delivery in Anatomically-Shaped Osteochondral Constructs (2018) (53)
- Quantitative phase microscopy of articular chondrocyte dynamics by wide-field digital interferometry. (2010) (53)
- The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors. (2009) (53)
- * CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. (2017) (52)
- Composition and transport properties of human ankle and knee cartilage (2006) (52)
- Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture (2011) (52)
- Adipose tissue is a critical regulator of osteoarthritis (2020) (52)
- Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain (2016) (52)
- Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing (2018) (52)
- Stem Cell Therapies for Knee Cartilage Repair (2014) (51)
- Proteomic Differences between Male and Female Anterior Cruciate Ligament and Patellar Tendon (2014) (50)
- Stem cell‐derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair (2020) (50)
- CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation‐Resistant Tissues (2017) (50)
- Comparison of Soccer Shin Guards in Preventing Tibia Fracture* (1999) (50)
- The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus. (2004) (50)
- Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration (2011) (50)
- A Mechano-chemical Model for the Passive Swelling Response of an Isolated Chondron under Osmotic Loading (2006) (49)
- Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair (2017) (47)
- Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers (2013) (47)
- Mechanical Properties and Gene Expression of Chondrocytes on Micropatterned Substrates Following Dedifferentiation in Monolayer (2009) (47)
- TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension (2019) (47)
- Viscoelastic properties of a synthetic meniscus implant. (2014) (46)
- Regional structure-function relationships in mouse aortic valve tissue. (2011) (45)
- Site-specific effects of compression on macromolecular diffusion in articular cartilage. (2008) (45)
- Genome Engineering for Personalized Arthritis Therapeutics. (2017) (45)
- Finite Element Modeling Predictions of Region-specific Cell-matrix Mechanics in the Meniscus (2006) (45)
- Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair. (2007) (45)
- Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble-induced jetting flow (2017) (44)
- Correlation of bony ingrowth to the distribution of stress and strain parameters surrounding a porous‐coated implant (1996) (44)
- Comparison of several digital and stereological methods for estimating surface area and volume of cells studied by confocal microscopy. (1999) (44)
- Use of Cartilage Derived From Murine Induced Pluripotent Stem Cells for Osteoarthritis Drug Screening (2014) (44)
- Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage. (2017) (44)
- Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. (2010) (44)
- The effect of hip stem material modulus on surface strain in human femora. (1998) (43)
- Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts. (2002) (43)
- N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions (2016) (43)
- Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. (2008) (43)
- Obesity alters the in vivo mechanical response and biochemical properties of cartilage as measured by MRI (2018) (42)
- Osmotic stress alters chromatin condensation and nucleocytoplasmic transport. (2011) (42)
- An axisymmetric boundary element model for determination of articular cartilage pericellular matrix properties in situ via inverse analysis of chondron deformation. (2010) (42)
- Three-dimensional finite element modeling of pericellular matrix and cell mechanics in the nucleus pulposus of the intervertebral disk based on in situ morphology (2011) (42)
- Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage. (2002) (41)
- Role of Piezo Channels in Joint Health and Injury. (2017) (41)
- Biaxial Strain Effects on Cells from the Inner and Outer Regions of the Meniscus (2006) (41)
- Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification during murine embryonic limb development (2019) (41)
- Interaction of lubricin with type II collagen surfaces: adsorption, friction, and normal forces. (2014) (41)
- Joint degeneration following meniscal allograft transplantation in a canine model: mechanical properties and semiquantitative histology of articular cartilage (2002) (40)
- Viscoelastic properties of the aortic valve interstitial cell. (2009) (40)
- Brief Report: Articular Ankle Fracture Results in Increased Synovitis, Synovial Macrophage Infiltration, and Synovial Fluid Concentrations of Inflammatory Cytokines and Chemokines (2015) (40)
- Matrix metalloproteinase activity and prostaglandin E2 are elevated in the synovial fluid of meniscus tear patients (2017) (39)
- A novel quantitative approach for evaluating contact mechanics of meniscal replacements. (2010) (39)
- High‐depth transcriptomic profiling reveals the temporal gene signature of human mesenchymal stem cells during chondrogenesis (2018) (38)
- Three‐dimensional morphology of the pericellular matrix of intervertebral disc cells in the rat (2007) (38)
- Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus. (2016) (37)
- Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter (2019) (37)
- IL-1β decreases the elastic modulus of human tenocytes (2006) (36)
- Sex Differences in Biomechanics Associated with Knee Osteoarthritis (2009) (35)
- Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip (2018) (35)
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- The influence of oxygen tension on the induction of nitric oxide and prostaglandin E2 by mechanical stress in articular cartilage. (2005) (33)
- Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations (2014) (33)
- Interleukin-1 inhibits osmotically induced calcium signaling and volume regulation in articular chondrocytes. (2008) (32)
- Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum. (2016) (32)
- Functional tissue engineering: the role of biomechanics in reparative medicine. (2002) (32)
- Pericellular Matrix Mechanics in the Anulus Fibrosus Predicted by a Three-Dimensional Finite Element Model and In Situ Morphology (2009) (32)
- Deformation-Induced Calcium Signaling in Articular Chondrocytes (1994) (31)
- From articular fracture to posttraumatic arthritis: a black box that needs to be opened. (2006) (30)
- Articular cartilage degeneration in post-collapse osteonecrosis of the femoral head. Radiographic staging, macroscopic grading, and histologic changes. (2005) (29)
- Regulation of human nucleus pulposus cells by peptide-coupled substrates. (2017) (29)
- Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain (2014) (28)
- An In Vitro System to Evaluate the Effects of Ischemia on Survival of Cells Used for Cell Therapy (2007) (28)
- A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues (2020) (28)
- MRI-based characterization of bone anatomy in the human knee for size matching of a medial meniscal implant. (2010) (28)
- Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression. (2007) (28)
- The sixth sense of the musculoskeletal system (2010) (28)
- Microscale diffusion properties of the cartilage pericellular matrix measured using 3D scanning microphotolysis. (2008) (28)
- Individual and Organizational Influences to the Use of Fire and Fuels Research by Federal Agency Managers (2008) (27)
- Dedifferentiated Human Articular Chondrocytes Redifferentiate to a Cartilage-Like Tissue Phenotype in a Poly(ε-Caprolactone)/Self-Assembling Peptide Composite Scaffold (2016) (27)
- Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity (2020) (27)
- High resistance of the mechanical properties of the chondrocyte pericellular matrix to proteoglycan digestion by chondroitinase, aggrecanase, or hyaluronidase. (2014) (27)
- Viscoelastic Properties of Intervertebral Disc Cells (1999) (26)
- IL-1beta decreases the elastic modulus of human tenocytes. (2006) (26)
- Selective Enzymatic Digestion of Proteoglycans and Collagens Alters Cartilage T1rho and T2 Relaxation Times (2018) (25)
- Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss. (2017) (25)
- Application of a Three-Dimensional Poroelastic BEM to Modeling the Biphasic Mechanics of Cell-Matrix Interactions in Articular Cartilage (REVISION). (2007) (25)
- Functional outcome measures in a surgical model of hip osteoarthritis in dogs (2016) (24)
- Intra-articular Depletion of Macrophages Increases Acute Synovitis and Alters Macrophage Polarity in the Injured Mouse Knee. (2020) (24)
- Computational Modeling in Biomechanics (2010) (24)
- Precision and Accuracy of a Transportable Dual-Energy X-ray Absorptiometry Unit for Bone Mineral Measurements in Guinea Pigs (2002) (23)
- Cell mechanics. (2000) (23)
- A neural network model for cell classification based on single-cell biomechanical properties. (2008) (22)
- Intergenerational Transmission of Diet‐Induced Obesity, Metabolic Imbalance, and Osteoarthritis in Mice (2020) (22)
- Mechanical stress and nitric oxide influence leukotriene production in cartilage. (2001) (22)
- Post-traumatic arthritis: Pathogenesis, diagnosis and management (2015) (22)
- The Effect of Intermittent Pneumatic Compression on Fracture Healing (2005) (22)
- Life-long caloric restriction does not alter the severity of age-related osteoarthritis (2014) (21)
- Meniscus-Derived Matrix Scaffolds Promote the Integrative Repair of Meniscal Defects (2019) (21)
- Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage. (2007) (21)
- A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues. (2019) (20)
- Designer Stem Cells: Genome Engineering and the Next Generation of Cell‐Based Therapies (2019) (20)
- Racial differences in gait mechanics associated with knee osteoarthritis (2009) (20)
- Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias (2014) (20)
- Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues (2021) (20)
- The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis. (2012) (20)
- Locomotor activity and gait in aged mice deficient for type IX collagen. (2010) (19)
- Composite Cellularized Structures Created from an Interpenetrating Polymer Network Hydrogel Reinforced by a 3D Woven Scaffold. (2018) (19)
- Comparison of Fixation Techniques of 3D-Woven Poly(ϵ-Caprolactone) Scaffolds for Cartilage Repair in a Weightbearing Porcine Large Animal Model (2018) (18)
- Chondrogenic, hypertrophic, and osteochondral differentiation of human mesenchymal stem cells on three‐dimensionally woven scaffolds (2019) (18)
- Universally Conserved Relationships between Nuclear Shape and Cytoplasmic Mechanical Properties in Human Stem Cells (2016) (18)
- Formation of Osteochondral Organoids from Murine Induced Pluripotent Stem Cells. (2020) (18)
- Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung (2015) (18)
- Taking stem cells beyond discovery: a milestone in the reporting of regulatory requirements for cell therapy. (2011) (17)
- Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. (2018) (17)
- Physiologic and pathologic effects of dietary free fatty acids on cells of the joint (2019) (17)
- The H-index: Use and overuse (2011) (16)
- Use of an insulating mask for controlling anisotropy in multilayer electrospun scaffolds for tissue engineering. (2010) (16)
- Multiphasic models in cell mechanics (2006) (16)
- Genome Engineering for Osteoarthritis: From Designer Cells to Disease-Modifying Drugs (2019) (15)
- Is Obesity a Disease of Stem Cells? (2020) (15)
- Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. (2015) (15)
- Immunoengineering the Next Generation of Arthritis Therapies (2020) (15)
- Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research. (2018) (15)
- Proteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury. (2019) (15)
- Single‐cell RNA sequencing reveals the induction of novel myeloid and myeloid‐associated cell populations in visceral fat with long‐term obesity (2021) (14)
- The slippery slope of arthritis. (2005) (14)
- On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach. (2017) (14)
- Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation. (2016) (14)
- Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels (2021) (13)
- Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis (2020) (13)
- A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery (2019) (13)
- Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease. (2019) (13)
- Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer. (2018) (13)
- The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes (2004) (13)
- Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway (2019) (12)
- Joint Injury and Post-Traumatic Arthritis (2012) (12)
- Effects of coronally slotted femoral prostheses on cortical bone strain. (1997) (12)
- CXCL10 is upregulated in synovium and cartilage following articular fracture (2017) (12)
- Functional tissue engineering: Ten more years of progress. (2014) (11)
- Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells (2021) (11)
- Tissue Engineering: Composite Three-Dimensional Woven Scaffolds with Interpenetrating Network Hydrogels to Create Functional Synthetic Articular Cartilage (Adv. Funct. Mater. 47/2013) (2013) (11)
- Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway (2020) (11)
- Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine (2018) (11)
- NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis. (2020) (11)
- Effects of myocardial infarction on the distribution and transport of nutrients and oxygen in porcine myocardium. (2012) (11)
- Energy recovery in individuals with knee osteoarthritis. (2014) (11)
- Chapter Eleven – Engineering Functional Tissues (2007) (11)
- Corrigendum to “Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice” [Osteoarthritis and Cartilage 2008;16(12): 1532–1538 (2012) (11)
- Biological resurfacing in a canine model of hip osteoarthritis (2021) (10)
- Functional Tissue Engineering and the Role of Biomechanical Signaling in Articular Cartilage Repair (2003) (10)
- Factors influencing the long-term behavior of extracellular matrix-derived scaffolds for musculoskeletal soft tissue repair. (2012) (10)
- Effects of dietary fatty acid content on humeral cartilage and bone structure in a mouse model of diet‐induced obesity (2019) (10)
- Isolation and Growth of Stem Cells (2011) (9)
- Transcriptomic analysis of bone and fibrous tissue morphogenesis during digit tip regeneration in the adult mouse (2019) (9)
- Engineering functional tissues: in vitro culture parameters (2020) (9)
- The miRNA‐mRNA interactome of murine induced pluripotent stem cell‐derived chondrocytes in response to inflammatory cytokines (2020) (9)
- Mapping the musculoskeletal system one cell at a time (2021) (9)
- Homing in on a biological joint replacement (2010) (8)
- On the mechanism of extremely low frequency (ELF) electric field interactions with living tissue (1992) (8)
- A6 FUNCTIONAL CHARACTERIZATION OF TRPV4 AS AN OSMOTICALLY SENSITIVE ION CHANNEL IN ARTICULAR CHONDROCYTES (2008) (7)
- Transient receptor potential vanilloid 4 as a regulator of induced pluripotent stem cell chondrogenesis (2021) (7)
- Chondroprotective role of the osmotically-sensitive ion channel TRPV4: Age- and sex-dependent progression of osteoarthritis in Trpv4 deficient mice (2011) (7)
- LONG TERM OUTCOMES OF BIOMATERIAL-MEDIATED REPAIR OF FOCAL CARTILAGE DEFECTS IN A LARGE ANIMAL MODEL (2021) (7)
- Deformation of Chondrocytes within the Extracellular Matrix of Articular Cartilage (1993) (7)
- Taxonomic changes in the gut microbiota are associated with cartilage damage independent of adiposity, high fat diet, and joint injury (2021) (6)
- miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells (2019) (6)
- The Current Status of Preclinical and Clinical Studies (2014) (6)
- Three-Dimensional Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures (2015) (6)
- 318. Targeted Genome Editing of Human Induced Pluripotent Stem Cells Using CRISPR/CAS9 to Generate a Knock-in Type II Collagen Reporter for the Purification of Chondrogenic Cells (2016) (6)
- Cell and tissue engineering (2000) (6)
- Observations on the growth of loose bodies in joints. (2002) (6)
- Single Cell Omics for Musculoskeletal Research (2021) (6)
- High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II (2021) (5)
- Functional Assessment of Engineered Tissues and Elements of Tissue Design (2002) (5)
- MOLECULAR DIFFUSION IN TISSUE-ENGINEERED CARTILAGE CONSTRUCTS : EFFECTS OF TIME AND CULTURE CONDITIONS (5)
- Biomechanical Factors in Tissue Engineering of Articular Cartilage (2004) (5)
- Mechanogenetics: harnessing mechanobiology for cellular engineering. (2021) (5)
- Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity. (2019) (5)
- An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties. (2020) (5)
- Mechanical properties of chondrocytes and chondrons (1996) (5)
- Lysyl hydroxylase (2015) (5)
- Increased Ca 2 + signaling through CaV 1 . 2 promotes bone formation and prevents estrogen deficiency – induced bone loss (2017) (5)
- In vivo biochemical and biomechanical properties of cartilage are affected by obesity. (2017) (4)
- Diet-Induced Obesity Significantly Increases the Severity of Post-Traumatic Arthritis in Mice (2012) (4)
- A Novel Polycarbonate-Urethane Meniscal Implant: From Bench to First Clinical Experience (2012) (4)
- Prolonged local delivery of IL-1Ra prevents post-traumatic arthritis in mice (2013) (4)
- Leptin mediates the regulation of muscle mass and strength by adipose tissue (2022) (4)
- New tools for Content Innovation and data sharing: Enhancing reproducibility and rigor in biomechanics research. (2017) (4)
- Gene Therapy for Follistatin Mitigates Systemic Metabolic Inflammation and Post-Traumatic Osteoarthritis in High-Fat Diet-Induced Obese Mice (2019) (4)
- Journal of Orthopaedic Research: Special Issue on Stem Cells (2019) (4)
- Adipose-Derived Adult Stem Cells for Cartilage Repair: 148 (2007) (3)
- TRPV4-mediated trigeminal pain: behavior assessments and mechanisms (2014) (3)
- Engineering Hyaluronic Acid for the Development of New Treatment Strategies for Osteoarthritis (2022) (3)
- Tissue Engineering: Advanced Material Strategies for Tissue Engineering Scaffolds (Adv. Mater. 32‐33/2009) (2009) (3)
- Biomechanical and Biochemical Cellular Response Due to Shock Waves (2008) (3)
- Osteoarthritis in a dish: the effects of pro-inflammatory cytokines on cartilage derived from induced pluripotent stem cells (2013) (3)
- The Use of Biomarkers in the Early Diagnosis of Septic Arthritis and Osteomyelitis—A Pilot Study (2022) (3)
- Nanotherapy Targeting NF-κB Attenuates Acute Pain After Joint Injury. (2019) (3)
- Fresh Osteochondral and Chondral Allograft Preservation and Storage Media: A Systematic Review of the Literature (2021) (2)
- Single Cell RNA Sequencing Reveals Heterogeneity of Human MSC Chondrogenesis: Lasso Regularized Logistic Regression to Identify Gene and Regulatory Signatures (2019) (2)
- Mechanical Signals as Regulators of Cartilage Degeneration and Regeneration. (2017) (2)
- CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation- resistant tissues Running head: Genome edited iPSCs for IL-1-resistant cartilage (2016) (2)
- Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks (2021) (2)
- 122 ASSESSMENT OF SERUM AND SYNOVIAL FLUID LEVELS OF IL-1α AND IL-1β IN A MOUSE MODEL OF POST-TRAUMATIC ARTHRITIS (2009) (2)
- Biphasic finite element predictions for region-specific meniscus cell-matrix mechanics (2006) (2)
- Adult Stem (ADAS) Cells (2003) (2)
- Design of a Polycarbonate-Urethane Meniscal Implant: Finite Element Approach (2009) (2)
- DEVELOPMENTAL AND OSTEOARTHRITIC CHANGES IN Col6a1 KNOCKOUT MICE: THE BIOMECHANICS OF COLLAGEN VI IN THE CARTILAGE PERICELLULAR MATRIX (2011) (2)
- A24 INHIBITION OF MATRIX METALLOPROTEINASES ENHANCES IN VITRO REPAIR OF THE MENISCUS (2008) (2)
- The Journal of Biomechanics: evolving with electronic publishing. (2013) (2)
- Meniscal Implant Biomechanical Performance: A Novel Quantitative Approach (2009) (2)
- Synthetic gene circuits for preventing disruption of the circadian clock due to interleukin-1–induced inflammation (2022) (2)
- Joint incongruity and biomarkers of bone metabolism as predictors of post-traumatic arthritis in mice (2015) (2)
- The Inhomogeneous Mechanical Properties of the Pericellular Matrix of Articular Cartilage Measured In Situ by Atomic Force Microscopy (2009) (1)
- Mechanical regulation of chondrogenesis (2013) (1)
- SEVERITY OF KNEE OSTEOARTHRITIS AND ITS EFFECT ON GAIT MECHANICS IN WALKING (2006) (1)
- Static compression inhibits matrix protein gene expression and increases collagenase gene expression in the meniscus (2002) (1)
- Articular Fracture in the Ankle Results in Increased Acute Local Inflammation (2014) (1)
- Biology of Adipose Tissue Stem Cells (2010) (1)
- Chondroprotective Effects of a Polycarbonate-Urethane Meniscal Implant: Semi-Quantitative Results in a Sheep Model (2010) (1)
- Strategies to Enhance Repair of the Meniscus: 149 (2007) (1)
- A TRP that makes us feel hyper (2012) (1)
- Inflammatory biomarkers of OA, IL-6 and leptin are modifiable in overweight/obese OA patients with a protocol that combines training in pain coping skills and weight management (2012) (1)
- The Role of PIEZO Ion Channels in the Musculoskeletal System. (2023) (1)
- Articular fracture upregulates lipid metabolites in human synovial fluid (2017) (1)
- Response to Dr. Schachar (2006) (1)
- Acute inflammatory response after severe joint injury potentially involved in the development of post-traumatic arthritis (2016) (1)
- 4.1 Genetically engineered elastin-like polypeptides for cartilage tissue regeneration (2007) (1)
- Computational Modeling of Cell Mechanics in Articular Cartilage (2010) (1)
- Arthritis That Develops After Joint Injury: Is It Post-Traumatic Arthritis or Post-Traumatic Osteoarthritis? (2015) (1)
- Highly efficient chondrogenic differentiation of human iPSCs and purification via a reporter allele generated by CRISPR-Cas9 genome editing (2018) (1)
- Pilot Study Analysis of Serum Cytokines to Differentiate Pediatric Septic Arthritis and Transient Synovitis (2021) (1)
- Cryogel Scaffold-Mediated Delivery of Adipose-Derived Stem Cells Promotes Healing in Murine Model of Atrophic Non-Union (2022) (1)
- Chondrogenesis and mineralization during in vitro culture of human stem cells on 3D-woven scaffolds (2010) (1)
- Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes (2021) (1)
- Design Optimization of a Polycarbonate-Urethane Meniscal Implant in the Sheep Knee: In-Vitro Study (2010) (1)
- Viscoelastic properties of a synthetic meniscus implant (2013) (1)
- Survey of Animal Models in Post-Traumatic Arthritis: Choosing the Right Model to Answer the Right Question (2015) (1)
- Bone Morphological Changes Correlate with Reduction in PTA after Articular Fracture in the MRL/MpJ Mouse (2015) (1)
- Aortic Valve Interstitial Cell Viscoelasticity (2007) (1)
- An Axisymmetric Elastic Layered Half-Space Model for Micropipette Aspiration of the Chondrocyte Pericellular Matrix (2001) (1)
- Reply to “Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?” by Wei et al. (2016) (1)
- TRPV4 activation enhances compressive properties and glycosaminoglycan deposition of equine neocartilage sheets (2022) (1)
- Fat implantation in lipodystrophic mice restores susceptibility to joint injury and osteoarthritis independent of body weight (2021) (1)
- Stem Cell Therapies for Post-Traumatic Arthritis (2015) (0)
- Corrigendum to “Exploring translational gaps between basic scientists, clinical researchers, clinicians, and consumers: Proceedings and recommendations arising from the 2020 mine the gap online workshop” [Osteoarthritis Cartilage Open 29 (2021) 100163] (2021) (0)
- Determination of In Situ Articular Cartilage Pericellular Matrix Properties via Inverse BEM Analysis of Chondron Deformation (2010) (0)
- Serum free fatty acid levels as predictors of the severity of obesity-associated osteoarthritis (2016) (0)
- 47 RACIAL DIFFERENCES IN GAIT MECHANICS, PAIN, AND SELF-REPORTED DISABILITY ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE (2007) (0)
- OSTEOARTHRITIS-RISK MUTATION IN PERICELLULAR MATRIX COL6A3 FIBRILS ALTERS BIOLOGIC RESPONSE OF CHONDROCYTES TO HYPER-PHYSIOLOGIC MECHANICAL LOADING CONDITIONS (2022) (0)
- The Role of Biomechanics in Articular Cartilage Repair (2001) (0)
- Osmotic Stress Affects Nuclear Morphology and Genome Architecture (2009) (0)
- 170 ADIPOKINES AND OSTEOARTHRITIS: SYNERGISTIC EFFECTS OF LEPTIN, FATTY ACIDS AND INTERLEUKIN-1 ON PROTEOGLYCAN BREAKDOWN (2007) (0)
- Characterization of a disease-inducible interleukin-4 gene therapy in murine articular chondrocytes (2020) (0)
- 209 THE ASSOCIATION OF CHONDROCYTE MECHANICAL PROPERTIES AND PHENOTYPIC EXPRESSION DURING CELLULAR EXPANSION ON MICROPATTERNED SUBSTRATES (2009) (0)
- Selective Enzymatic Digestion of Proteoglycans and Collagens Alters Cartilage T1rho and T2 Relaxation Times (2018) (0)
- BIPHASIC PROPERTIES OF NORMAL AND OSTEOARTHRITIC HUMAN CHONDRONS (0)
- 91 A PRECISE AND SCALABLE METHOD OF MICE KNEE SYNOVIAL FLUID COLLECTION FOR USE IN BIOMARKER ANALYSES (2007) (0)
- Dietary fatty acids differentially affect the development of injury-induced osteoarthritis with diet-induced obesity in mice (2013) (0)
- 2011: A Novel Polycarbonate-Urethane Meniscal Implant: From Bench to First Clinical Experience (2010) (0)
- 33 EXTREME OBESITY DUE TO IMPAIRED LEPTIN SIGNALING DOES NOT CAUSE OSTEOARTHRITIS IN MICE (2007) (0)
- A Novel Role for TRPV4 in Articular Cartilage Homeostasis (2010) (0)
- Adipose Tissue-Derived Stromal Cells Grown in Three-Dimensional Aliginate Constructs Display a Chondrogenic Phenotype (2000) (0)
- Targeted genome and epigenome editing for OA research and therapy (2018) (0)
- Voluntary Exercise and the Development of Osteoarthritis in Mice Fed a High-fat Diet (2006) (0)
- 504. Targeted Genome Engineering of Induced Pluripotent Stem Cells To Produce Auto-Regulated Inflammation Resistance for Musculoskeletal Regenerative Medicine (2015) (0)
- Taxonomic changes in the microbiota are associated with cartilage damage in a mouse model of high-fat diet and OA (2021) (0)
- Adipose Tissue-Derived Adult Stem Cells (2019) (0)
- Hyper-Physiologic Mechanical Loading Conditions Cause A Shift In The Epigenetic Landscape In Neo-Cartilage Organoids (2023) (0)
- Electronic publishing and the Journal of Biomechanics (2005) (0)
- Faculty Opinions recommendation of Chondroitin sulfate reduces the friction coefficient of articular cartilage. (2007) (0)
- Loughborough University Institutional Repository Myoelectric stimulation on peroneal muscles with electrodes of the muscle belly size attached to the upper shank gives the best e ect in resisting simulated ankle sprain motion (2016) (0)
- Unanswered Questions and Future Directions in Post-Traumatic Arthritis (2015) (0)
- Inflammatory Cytokine Il-1α Up-Regulates Piezo1 and Hyper-Sensitizes Chondrocytes to Compression (2016) (0)
- 1-17 INTRA-ARTICULAR INJECTION OF PURIFIED MESENCHYMAL STEM CELLS FROM C57BL/6 OR MRL/MPJ “SUPERHEALER” MICE PREVENTS POSTTRAUMATIC ARTHRITIS (2011) (0)
- Chondrogenic Differentiation of Human-Induced Pluripotent Stem Cells. (2023) (0)
- Development of Intra-Articular Drug Delivery to Alter Progression of Arthritis Following Joint Injury (2013) (0)
- THE ROLE OF ADIPOSE-CARTILAGE CROSSTALK IN OSTEOARTHRITIS (2023) (0)
- Injectable laminin-functionalized hydrogel for cell delivery to the intervertebral disc (2013) (0)
- The effect of conditional macrophage depletion on development of injury-induced knee OA in obese transgenic MAFIA mice (2015) (0)
- Supplemental Information miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells (2019) (0)
- The transient receptor potential vanilloid 4 ion channel regulates the biosynthetic response of chondrocytes to dynamic loading (2013) (0)
- Acknowledgement to referees (2005) (0)
- Life-long caloric restriction does not alter the severity of age-related osteoarthritis (2014) (0)
- Corrigendum to “In situ friction measurement on murine cartilage by atomic force microscopy” [J. Biomech. 41(3) (2008) 541–548] (2010) (0)
- Assessment of Biomarkers Associated with Joint Injury and Subsequent Post-Traumatic Arthritis (2014) (0)
- The Relationship Between Gait Mechanics and Radiographic Disease Severity in Knee Osteoarthritis (2012) (0)
- Form and function of the knee meniscus (2018) (0)
- BIOMECHANICS AND MECHANOBIOLOGY OF OSTEOARTHRITIS: THE YEAR IN REVIEW (2007) (0)
- Special Issue on Computational Bioengineering (2007) (0)
- capacity and resistance against diet-induced obesity TRPV4 deficiency increases skeletal muscle metabolic (2015) (0)
- Intracellular measurements of strain transfer using texture correlation (2006) (0)
- Osmotic or Chemical Activation of the TRPV4 Ion Channel Enhances the Development of Chondrocyte-Based Tissue Engineered Cartilage (2013) (0)
- Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction (2022) (0)
- Relationship between Quantitative T1ρ and T2 Relaxation Times and the Biochemical and Biomechanical Properties of Osteoarthritic Cartilage (2015) (0)
- A disease-risk mutation in COL6A3 alters the biologic response of chondrocytes to hyper-physiologic mechanical loading (2021) (0)
- In vitro analysis of genome‐engineered muscle‐derived stem cells for autoregulated anti‐inflammatory and antifibrotic activity (2022) (0)
- Identification of biomarkers indicative of synovitis in the mouse articular fracture model of PTA (2017) (0)
- Author response: Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway (2020) (0)
- Optimization of Meniscus Cell Transduction Using Lentivirus and Adeno-Associated Virus for Gene Editing and Tissue Engineering Applications (2019) (0)
- Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward mechanism (2020) (0)
- Biomechanical Versus Clinical Considerations in the Development of a Novel Polycarbonate-Urethane Meniscus Implant (2013) (0)
- Modulation of TRPV4 Protects against Degeneration Induced by Sustained Loading and Promotes Matrix Synthesis in the Intervertebral Disc (2022) (0)
- Multiscale Mechanics of Articular Cartilage: Potentials and Challenges of Coupling Musculoskeletal, Joint, and Microscale Computational Models (2012) (0)
- Nano-Scale and Micro-Scale Substrate Architectures Direct Collagen Alignment in Tendon Neo-Tissue Formation (2013) (0)
- Characterization of the extremely low frequency (ELF) electric field interactions with living tissue (1992) (0)
- Interaction of Lubricin with Collagen II Surfaces: Adsorption, Friction, and Normal Forces (2014) (0)
- Novel approaches to joint repair (2014) (0)
- Three-Dimensional Woven Composite Materials for Impact Protection: Application to Soccer Shin Guards (2000) (0)
- Anterior Cruciate Transection/Disruption Models of Post-Traumatic Arthritis (2015) (0)
- Fat stem cells (2008) (0)
- Oxygen, nitric oxide, and osteoarthritis (2006) (0)
- Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis (2021) (0)
- Keynote - Biomechanical Factors in Osteoarthritis: From Organism to Organelle (2007) (0)
- M-5 Can A Polycarbonate-Urethane Meniscal Provide Chondroprotection? Results in a Sheep Model (2010) (0)
- Inhalt Band 35, Heft 3, June 2008 (2008) (0)
- The Transient Receptor Potential Vanilloid 4 Ion Channel Regulates The Physiologic Response Of Chondrocytes To Dynamic Loading (2014) (0)
- Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter (2020) (0)
- Initial displacement of the intra‐articular surface after articular fracture correlates with PTA in C57BL/6 mice but not “superhealer” MRL/MpJ mice (2020) (0)
- Heart valve interstitial cell mechanical properties: Effects of right and left side heart transvalvular pressures (2005) (0)
- Trimming the fat - is leptin crosstalk the link between obesity and osteoarthritis? (2022) (0)
- A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading (2023) (0)
- FUNCTIONAL PROPERTIES OF BIOMATERIALS FOR CARTILAGE TISSUE ENGINEERING USING ADIPOSE DERIVED ADULT STEM CELLS (0)
- Tunable expression of IL-1Ra in genetically modified mesenchymal stem cells for cartilage tissue engineering (2013) (0)
- Genome Engineering for Personalized Arthritis Therapeutics A Diseases of (2017) (0)
- Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy (2023) (0)
- Functional tissue engineering of articular cartilage for biological joint resurfacing—The 2021 Elizabeth Winston Lanier Kappa Delta Award (2021) (0)
- Meniscus-Derived Matrix Scaffolds Promote the Integrative Repair of Meniscal Defects (2019) (0)
- Altered cartilage mechanics in knee joints of type IX collagen deficient mice (2006) (0)
- Genome Engineering for Osteoarthritis: From Designer Cells to Disease-Modifying Drugs (2019) (0)
- The Journal of Biomechanics thanks Professor Rik Huiskes (2009) (0)
- 3D hybrid scaffolds for engineering functional tissue replacements (2013) (0)
- FORCE AND ENERGY DISSIPATION OF SOCCER SHIN GUARDS (1998) (0)
- Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells (2018) (0)
- Evaluation Of The Compositional And Functional Properties Of Articular Cartilage Using T1rho And T2 Relaxation Imaging (2015) (0)
- Podium Presentations S 23 A 22 WHOLE DEGRADOME EXPRESSION PROFILING IN NORMAL AND OSTEOARTHRITIC CARTILAGE (2008) (0)
- Gene therapy for follistatin decreases systemic inflammation and pain sensitivity following knee injury in high-fat diet induced obese mice (2017) (0)
- Characterization of Mechanotransensitivity of Articular Chondrocytes (2014) (0)
- Post-traumatic Arthritis: An Update (2013) (0)
- Pattern of synovial fluid cytokine biomarkers in the knee after anterior cruciate ligament tear suggests an initial repair response (2018) (0)
- In Memoriam: Charles H. Turner (2010) (0)
- B cells drive tertiary lymphoid organ formation in ileal inflammation (2022) (0)
- Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds (2018) (0)
- International Cartilage Repair Society Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis 1 (0)
- Osmotic Stress Initiates Intracellular Calcium Waves in Chondrocytes Through Extracellular Influx and the Inositol Phosphate Pathway (1999) (0)
- In situ chondrocyte calcium signaling in response to osmotic stress: The role of TRPV4 ion channel (2002) (0)
- Exploring translational gaps between basic scientists, clinical researchers, clinicians, and consumers: Proceedings and recommendations arising from the 2020 mine the gap online workshop (2021) (0)
- TRPV4 as a therapeutic target for joint diseases (2014) (0)
- 502. Biomaterial-Mediated Lentiviral Delivery of Anti-Inflammatory Genes in Cartilage-Derived Matrix Hemispheres (2016) (0)
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